Rainha Passi, Justyna Cholewa-Waclaw, Ryan Wereski, Matthew Bennett, Stefan Veizades, Bronwyn Berkeley, Andrea Caporali, Ziwen Li, Julie Rodor, Mieke Dewerchin, Nicholas L Mills, Abdelaziz Beqqali, Mairi Brittan, Andrew H Baker
BACKGROUND: COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can affect multiple organ systems, including the pulmonary vasculature. Endothelial cells (ECs) are thought to play a key role in the propagation of COVID-19, however, our understanding of the exact scale of dysregulation sustained by the pulmonary microvasculature (pMV) remains incomplete. Here we aim to identify transcriptional, phenotypic, and functional changes within the pMV induced by COVID-19...
January 22, 2024: Vascular Pharmacology