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Integrative Cancer Therapies

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https://www.readbyqxmd.com/read/28381120/simultaneous-assessment-of-the-efficacy-and-toxicity-of-marine-mollusc-derived-brominated-indoles-in-an-in-vivo-model-for-early-stage-colon-cancer
#1
Babak Esmaeelian, Kirsten Benkendorff, Richard K Le Leu, Catherine A Abbott
The acute apoptotic response to genotoxic carcinogens animal model has been extensively used to assess the ability of drugs and natural products like dietary components to promote apoptosis in the colon and protect against colorectal cancer (CRC). This work aimed to use this model to identify the main chemopreventative agent in extracts from an Australian mollusc Dicathais orbita, while simultaneously providing information on their potential in vivo toxicity. After 2 weeks of daily oral gavage with bioactive extracts and purified brominated indoles, mice were injected with the chemical carcinogen azoxymethane (AOM; 10 mg/kg) and then killed 6 hours later...
April 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28150504/acupuncture-and-reflexology-for-chemotherapy-induced-peripheral-neuropathy-in-breast-cancer
#2
Idan Ben-Horin, Peretz Kahan, Larisa Ryvo, Moshe Inbar, Shahar Lev-Ari, Ravit Geva
BACKGROUND: Treatment of chemotherapy-induced peripheral neuropathy (CIPN), which affects approximately 30% to 40% of patients treated with neuropathy-causing agents, is mainly symptomatic. Currently available interventions are of little benefit. STUDY DESIGN: This study was conducted as a retrospective analysis of the efficacy of acupuncture and reflexology in alleviating CIPN in breast cancer patients. METHODS: Medical records of 30 consecutive breast cancer patients who received both chemotherapy and treatment for CIPN according to our Acupuncture and Reflexology Treatment for Neuropathy (ART-N) protocol between 2011 and 2012 were reviewed...
February 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28150503/yoga-program-for-high-grade-glioma-patients-undergoing-radiotherapy-and-their-family-caregivers
#3
Kathrin Milbury, Smitha Mallaiah, Anita Mahajan, Terri Armstrong, Shioa-Pei Weathers, Kathryn E Moss, Nazli Goktepe, Amy Spelman, Lorenzo Cohen
BACKGROUND: Despite their high symptom burden and poor prognosis, evidence-based supportive care interventions for adults with high-grade glioma (HGG) and their caregivers are lacking. Thus, we aimed to establish feasibility of a patient-caregiver dyadic yoga program (DYP) for newly diagnosed HGG patients and their family caregivers targeting quality-of-life (QOL) outcomes. METHOD: In this single-arm pilot trial, dyads participated in a 12-session DYP program across the course of patients' radiotherapy...
January 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28110564/recruitment-to-the-breast-activity-and-healthy-eating-after-diagnosis-b-ahead-randomized-controlled-trial
#4
Mary Pegington, Judith E Adams, Nigel J Bundred, Anna M Campbell, Anthony Howell, Sacha J Howell, Shaun Speed, Jane Wolstenholme, Michelle N Harvie
Excess weight at breast cancer diagnosis and weight gain during treatment are linked to increased breast cancer specific and all-cause mortality. The Breast-Activity and Healthy Eating After Diagnosis (B-AHEAD) trial tested 2 weight loss diet and exercise programmes versus a control receiving standard written advice during adjuvant treatment. This article identifies differences in characteristics between patients recruited from the main trial site to those of the whole population from that site during the recruitment period and identifies barriers to recruitment...
January 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28110563/the-hexane-fraction-of-bursera-microphylla-a-gray-induces-p21-mediated-antiproliferative-and-proapoptotic-effects-in-human-cancer-derived-cell-lines
#5
Sabrina Adorisio, Alessandra Fierabracci, Giulia Gigliarelli, Isabella Muscari, Lorenza Cannarile, Anna Marina Liberati, Maria Carla Marcotullio, Carlo Riccardi, Massimo Curini, Ramon Enrique Robles Zepeda, Domenico V Delfino
Bursera microphylla (BM), one of the common elephant trees, is widely distributed in the Sonoran desert in Mexico. The Seri ethnic group in the Sonoran desert uses BM as an anti-inflammatory and painkiller drug for the treatment of sore throat, herpes labialis, abscessed tooth, and wound healing. Dried stems and leaves of BM are used in a tea to relieve painful urination and to stimulate bronchial secretion. Furthermore, BM is used for fighting venereal diseases. To investigate the effects of the hexane fraction of resin methanol extract (BM-H) on cell growth, the acute myeloid cell line (OCI-AML3) was treated with 250, 25, or 2...
January 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28102098/a-randomized-double-blind-placebo-controlled-trial-of-fruit-and-vegetable-concentrates-on-intermediate-biomarkers-in-head-and-neck-cancer
#6
Mridul Datta, Edward G Shaw, Glenn J Lesser, L Douglas Case, Mara Z Vitolins, Charles Schneider, Bart Frizzell, Christopher Sullivan, Mark Lively, Elizabeth Franzmann, Jennifer J Hu
BACKGROUND: Head and neck cancer (HNC) patients are at an increased risk for developing second primary tumors (SPTs). Diets rich in fruits and vegetables (FVs) may lower HNC risk. FV concentrates may offer a potential alternative to increasing FV intake. METHODS: We conducted a randomized, double-blind, placebo-controlled trial to evaluate whether Juice PLUS+ (JP; a commercial product with multiple FV concentrates) has an effect on p27 and Ki-67, biomarkers associated with the risk of SPTs...
January 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28056563/a-survey-of-licensed-acupuncturists-in-the-san-francisco-bay-area
#7
Donald Abrams, Michael McCulloch, Misha Cohen, Mike Liaw, Deborah Silverman, Carla Wilson
BACKGROUND: Many cancer patients seek traditional Chinese medicine (TCM), the prevalence varying with diagnosis, comorbidities, and demographics. Interventions sought include acupuncture, massage, herbs, diet, and exercise, usually combined with conventional therapies. It is not known what proportion of TCM practitioners care for cancer patients, their cancer specific training or caseload, what interventions they employ, their outcomes, and their communication patterns with conventional oncologists...
January 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/27923905/%C3%AE-lapachone-inhibits-lung-metastasis-of-colorectal-cancer-by-inducing-apoptosis-of-ct26-cells
#8
Ji-Ye Kee, Yo-Han Han, Jinbong Park, Dae-Seung Kim, Jeong-Geon Mun, Kwang Seok Ahn, Hyun-Jung Kim, Jae-Young Um, Seung-Heon Hong
BACKGROUND: β-Lapachone is a quinone-containing compound found in red lapacho (Tabebuia impetiginosa, syn. T avellanedae) trees. Lapacho has been used in traditional medicine by several South and Central American indigenous people to treat various types of cancer. The purpose of this study was to investigate the antimetastatic properties of β-lapachone and the underlying mechanisms using colon cancer cells. METHODS: This research used metastatic murine colon cancer cell lines, colon 26 (CT26) and colon 38 (MC38)...
December 5, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/27923904/augmentation-of-cytolytic-activity-in-murine-natural-killer-cells-and-inhibition-of-tumor-growth-by-the-ethanol-fraction-of-oyster-extract
#9
Kaito Sakaguchi, Ming Zhong, Saeko Kawai, Yoshio Shimizu, Eiichi Gohda
A reduced number and/or reduced activity of natural killer (NK) cells, which are important for defense against a variety of cancers and viral infections, occur under various stress conditions and in patients with various diseases. In this article, we report that the 30% to 50% ethanol precipitate of oyster extract (EPOE50) dose-dependently enhanced the activity of mouse spleen NK cells in vitro and in vivo. The activity of EPOE50 was eluted with a molecular weight of about 2000 by gel filtration and was inactivated by periodate but not by proteinase K...
December 5, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28345362/mindfulness-based-movement
#10
Alexander R Lucas, Heidi D Klepin, Stephen W Porges, W Jack Rejeski
Compelling evidence suggests that physical activity is an effective intervention for cancer survivors, including for those undergoing active cancer treatments. However, to date most evidence has emerged from interventions that have promoted moderate to vigorous physical activity. In this conceptual review, we argue that attention should be given to the entire continuum of physical activity from reducing sedentary behavior to increasing higher levels of physical activity when possible. In addition, considerable evidence in the cancer literature supports the value of mindfulness-based interventions as a means of helping patients and survivors cope with the variety of threats that accompany this disease...
December 1, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28088871/herbal-medicine-practices-of-patients-with-liver-cancer-in-peru
#11
Teresa Rojas Rojas, Geneviève Bourdy, Eloy Ruiz, Juan-Pablo Cerapio, Pascal Pineau, Jacques Gardon, Franco Doimi, Xavier Deparis, Eric Deharo, Stéphane Bertani
RATIONALE: The highest burden of liver cancer occurs in developing countries, where the use of herbal medicine (HM) is still widespread. Despite this trend, few studies have been conducted to report HM practices of patients with a hepatic tumor in the developing world. Hence, this study aimed to document the use of HM among patients with liver cancer in Peru. STUDY DESIGN AND METHODS: A comparative behavioral epidemiological survey was conducted among liver cancer patients attending the National Cancer Institute of Peru...
December 1, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28050925/bone-mineral-density-balance-performance-balance-self-efficacy-and-falls-in-breast-cancer-survivors-with-and-without-qigong-training
#12
Shirley S M Fong, Anna W M Choi, W S Luk, Timothy T T Yam, Joyce C Y Leung, Joanne W Y Chung
PURPOSE: A deterioration in bone strength and balance performance after breast cancer treatment can result in injurious falls. Therefore, interventions need to be developed to improve the bone strength and balance ability of breast cancer survivors. This cross-sectional exploratory study aimed to compare the bone mineral density (BMD), balance performance, balance self-efficacy, and number of falls between breast cancer survivors who practiced qigong, breast cancer survivors who did not practice qigong, and healthy individuals...
December 1, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28050924/inpatient-acupuncture-at-a-major-cancer-center
#13
M Kay Garcia, Lorenzo Cohen, Michael Spano, Amy Spelman, Yousra Hashmi, Alejandro Chaoul, Qi Wei, Gabriel Lopez
BACKGROUND: Use of complementary and integrative therapies is increasing among cancer patients, but data regarding the impact treatments such as acupuncture have in an inpatient oncology setting are limited. METHODS: Patients who received acupuncture in an inpatient hospital environment between December 2014 and December 2015 were asked to complete a modified Edmonton Symptom Assessment Scale (ESAS; 0-10 scale) before and after each visit. Pre- and post-treatment scores were examined for each symptom using paired t tests...
December 1, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28024424/the-relationship-between-health-related-quality-of-life-and-survival-in-metastatic-colorectal-cancer-patients-treated-with-korean-medicine
#14
Sora Park, Wankyu Eo, Sookyung Lee
OBJECTIVES: This study aimed to identify the relationship between health-related quality of life (HRQoL) measured by the Functional Assessment Cancer Therapy-General (FACT-G) and survival in metastatic colorectal cancer (mCRC) patients. METHODS: The clinical characteristics and FACT-G scores were retrospectively reviewed in mCRC patients who visited the Cancer Center of Korean Medicine. The overall survival (OS) was calculated and compared using the Kaplan-Meier method and log-rank test...
December 1, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28024420/assessing-the-correlation-between-physical-activity-and-quality-of-life-in-advanced-lung-cancer
#15
Brett C Bade, Mary C Brooks, Sloan B Nietert, Ansley Ulmer, D David Thomas, Paul J Nietert, JoAnn B Scott, Gerard A Silvestri
BACKGROUND AND OBJECTIVE: Increasing physical activity (PA) is safe and beneficial in lung cancer (LC) patients. Advanced-stage LC patients are under-studied and have worse symptoms and quality of life (QoL). We evaluated the feasibility of monitoring step count in advanced LC as well as potential correlations between PA and QoL. METHODS: This is a prospective, observational study of 39 consecutive patients with advanced-stage LC. Daily step count over 1 week (via Fitbit Zip), QoL, dyspnea, and depression scores were collected...
December 1, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28008780/carnosine-inhibits-the-proliferation-of-human-cervical-gland-carcinoma-cells-through-inhibiting-both-mitochondrial-bioenergetics-and-glycolysis-pathways-and-retarding-cell-cycle-progression
#16
Yun Bao, Saidan Ding, Jiaoyan Cheng, Yuan Liu, Bingyu Wang, Huijuan Xu, Yao Shen, Jianxin Lyu
Carnosine has been demonstrated to play an antitumorigenic role in certain types of cancer. However, its underlying mechanism is unclear. In this study, the roles of carnosine in cell proliferation and its underlying mechanism were investigated in the cultured human cervical gland carcinoma cells HeLa and cervical squamous carcinoma cells SiHa. The results showed that carnosine exerted a significant inhibitory effect on the proliferation of HeLa cells, whereas its inhibitory action on the proliferation of SiHa cells was much weaker...
December 1, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28008779/the-effect-of-undaria-pinnatifida-fucoidan-on-the-pharmacokinetics-of-letrozole-and-tamoxifen-in-patients-with-breast-cancer
#17
Shreya Tocaciu, Lesley J Oliver, Ray M Lowenthal, Gregory M Peterson, Rahul Patel, Madhur Shastri, Georgia McGuinness, Inger Olesen, J Helen Fitton
BACKGROUND: Although the use of complementary and alternative medicines is widespread in cancer patients, clinical evidence of their benefits is sparse. Furthermore, while they are often assumed to be safe with regard to concurrent use of anticancer therapies, few studies have been carried out to investigate possible interactions. Fucoidans are a group of sulfated carbohydrates, derived from marine brown algae, which have long been used as dietary supplements due to their reported medicinal properties, including anticancer activity...
December 1, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28008778/physical-activity-during-and-after-adjuvant-treatment-for-breast-cancer
#18
Maria Browall, Sara Mijwel, Helen Rundqvist, Yvonne Wengström
BACKGROUND: In oncology, physical activity (PA) is recognized to improve psychological and physiological functions. Motivating women with breast cancer to sustain a physically active lifestyle is important for promoting positive health after diagnosis. To review and synthesize what is known about how women with breast cancer experience supervised and unsupervised PA during and after adjuvant treatment. PubMed, PsycINFO, and CINAHL were searched, yielding 994 citations. The final review included 17 articles published between 2004 and 2014 in English...
December 1, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/27856840/e-only-section
#19
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/27856839/celebrating-15-years-of-publication-of-integrative-cancer-therapies-with-positive-change
#20
EDITORIAL
Keith I Block
No abstract text is available yet for this article.
December 2016: Integrative Cancer Therapies
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