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International Journal of Lower Extremity Wounds

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https://www.readbyqxmd.com/read/30334466/acellular-fish-skin-grafts-and-pig-urinary-bladder-matrix-assessed-in-the-collagen-induced-arthritis-mouse-model
#1
Skuli Magnusson, Hilmar Kjartansson, Baldur Tumi Baldursson, Katrin Astradsdottir, Magnus S Ågren, Hilmar Hilmarsson, Gudmundur Fertram Sigurjonsson
It is vital that cellular- and tissue-based products (CTPs) used for wound treatment do not provoke autoimmunity. In this study, the immunogenic response to extracts of 2 CTPs of piscine and porcine origin was assessed in the collagen-induced arthritis model. Male DBA/1J mice were divided into 4 groups, each composed of 7 to 9 animals. Each animal was injected with one of following to assess their immune responses: (1) bovine type II collagen (100 µg) in Freund's adjuvant, (2) extract of piscine skin (100 µg) in Freund's adjuvant, (3) extract of porcine urinary bladder matrix (100 µg) in Freund's adjuvant, or (4) Freund's adjuvant alone (control) at the beginning of the experiment and 3 weeks later...
October 18, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30282510/the-use-of-a-novel-super-oxidized-solution-on-top-of-standard-treatment-in-the-home-care-management-of-postsurgical-lesions-of-the-diabetic-foot-reduces-reinfections-and-shortens-healing-time
#2
Elisabetta Iacopi, Lorenza Abbruzzese, Chiara Goretti, Nicola Riitano, Alberto Piaggesi
There are still many unmet needs in the treatment of chronic wounds, especially regarding microenvironment modulation. Nexodyn is a novel super-oxidized solution capable of contrast bacterial proliferation. We aimed to evaluate if this solution, on top of standard of care, was safe and effective in improving diabetic foot outcome. We selected 50 patients admitted in our department to be submitted to surgery for acute diabetic foot infection. All patients were left open to heal for secondary intent. We divided patients into 2 groups: Group A (n = 25, male/female = 17/8, age = 67...
October 4, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30282495/future-of-biologics-in-healing-angiopathic-wounds
#3
Massimo Papi, Kittipan Rerkasem, Raj Mani
No abstract text is available yet for this article.
October 4, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30270692/a-rare-cause-of-leg-ulcer-calcinosis-cutis-as-a-part-of-crest-syndrome
#4
Evren Odyakmaz Demirsoy, Cansu Çatal, Ayten Yazıcı, Dilek Bayramgurler
Leg ulcers are not a disease themselves, they are a symptom of a disease. To manage them properly, finding the correct diagnosis of the disease is mandatory. Our case is a model to underline that leg ulcers are a significant burden for the patient, because leg ulcer got ahead of the patient's other serious complaints such as Raynaud's phenomenon or sclerodactyly. Furthermore, our patient is also a model, and an attentive clinical evaluation is inevitable to find the correct diagnosis. We present our case aiming to underline the significance of full dermatologic examination in each ulceration to discover underlying disease...
October 1, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30178693/improving-would-healing-ability-by-training-experiences-of-china
#5
Yufeng Jiang, Shuliang Lu, Bin Wen, Xiaobing Fu
In China, chronic wounds are an important issue. However, wound care knowledge and the skill of health care professionals varies among hospitals and cities. A training program in wound care in China was completed in 2015 and achieved great success. To facilitate expertise in wound healing in China, a sequential training project supported by the Wound Healing Union and the Chinese Medical Doctor Association was initiated. The aim of the training program was mainly to improve experience and skills in wound healing...
September 4, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30141366/common-pathogens-and-antibiotic-sensitivity-profiles-of-infected-diabetic-foot-ulcers-in-saudi-arabia
#6
Mousab Yousef Al Ayed, Mutasem Ababneh, Asirvatham Alwin Robert, Aus Alzaid, Rania Ahmed Ahmed, Ahmed Salman, Maha Ali Musallam, Mohamed Abdulaziz Al Dawish
We sought to define the type and antibiotic sensitivity response of pathogens isolated from diabetic foot ulcers based on ulcer location and Wagner classification. This retrospective analysis was done among 126 patients between 40 and 70 years of age at the Prince Sultan Military Medical City, Riyadh, Saudi Arabia, using the swab culture method for microbiological assessment. Data on demographic variables, ulcer sites (location), and depth of ulcer (Wagner classification) were also collected. A total of 134 pathogens were isolated from 126 patients...
August 24, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30141361/negative-pressure-wound-therapy-promotes-wound-healing-by-enhancing-angiogenesis-through-suppression-of-nlrx1-via-mir-195-upregulation
#7
Yu Liu, Ningning Tang, Ke Cao, Shaohua Wang, Sijie Tang, Honghui Su, Jianda Zhou
Negative-pressure wound therapy (NPWT) is one of the most advanced therapeutic methods in the treatment of various hard-to-heal acute and refractory chronic wounds. Recent emerging evidence points to a role of the microRNA-mediated regulation of angiogenesis in ischemic tissues, and a series of microRNAs associated with angiogenesis have been successively identified. In this study, we found that miR-195 expression was significantly upregulated and the microvessel density (MVD) was increased in granulation tissue collected 7 days after NPWT compared with those in the pre-NPWT tissue...
August 24, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30222082/horizon-scanning-in-lower-extremity-wound-management
#8
Kittipan Rerkasem, Massimo Papi, Raj Mani
No abstract text is available yet for this article.
September 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30222081/silver-sulfadiazine-and-cerium-nitrate-in-ischemic-skin-necrosis-of-the-leg-and-foot-results-of-a-prospective-randomized-controlled-study
#9
Julian Vitse, Huidi Tchero, Sylvie Meaume, Anne Dompmartin, Julie Malloizel-Delaunay, Chloé Géri, Christine Faure, Christian Herlin, Luc Teot
Flammacerium is a topical treatment composed of silver sulfadiazine and cerium nitrate initially used in burns. The objective was to assess the effectiveness of silver sulfadiazine and cerium nitrate on ischemic necrosis wounds of the lower limb as an alternative to amputation for a period of 12 weeks. Patients were prospectively randomized to receive silver sulfadiazine and cerium nitrate or standard care. Patients included adults with an ischemic wound of the lower limb, with necrosis covering over at least 50%...
September 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30222080/diabetic-foot-fungal-osteomyelitis-no-longer-unknown-and-hidden
#10
Prashanth R J Vas, Periklis Panagopoulos, Nikolaos Papanas
No abstract text is available yet for this article.
September 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30092692/fungal-osteomyelitis-in-diabetic-foot-infections-a-case-series-and-comparative-analysis
#11
Garneisha M Torrence, Brian M Schmidt
Fungal osteomyelitis (OM) is relatively rare. There is scarce literature discussing fungal OM in diabetic foot infections (DFIs). This case series explores the clinical characteristics of patients treated at a large tertiary academic center for DFI and found to have a causative agent of fungal origin in their bone on surgical intervention. Between July 2017 and March 2018, a prospective longitudinal analysis was performed of patients with diabetes admitted to our institution who underwent operative management of OM...
September 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30111220/prevalence-of-foot-complications-in-people-with-type-2-diabetes-mellitus-a-community-based-survey-in-rural-udupi
#12
Arun Gundmi Maiya, Shubha Gundmi, Prabhath Matpady, Radhika Jadhav, Ramachandra Lingadakai, Manjunatha Hande, Veena G Kamath, K N Shivashankar, P Chinmayee, Animesh Hazari, Nagarathna Shastri, Rohini Hande, Mads Mundt Loftager, Sundar Kumar Veluswamy, Edward Jude
The objective of the study was to determine the prevalence of foot complications among people with type 2 diabetes mellitus in the rural part of Udupi district, Karnataka, India. A cross-sectional observational study design was conducted in the rural area of Udupi district. In the study, accredited social health activists were trained to screen people with type 2 diabetes mellitus for diabetic foot complications at a community level. Adults over 35 years of age were screened for the presence of type 2 diabetes mellitus by accredited social health activists who reside in the rural part of Udupi district...
August 16, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30111204/therapeutic-intervention-of-aloe-gel-containing-nano-sized-and-micron-sized-silver-sulfadiazine-gel-on-second-degree-burn-a-comparative-study
#13
Md Abul Barkat, Harshita, Faheem Hyder Pottoo, Satya Prakash Singh, Farhan J Ahmad
The current work focuses on the formulation development, optimization, and in vivo assessment of nano-sized silver sulfadiazine ( nSSD) and micron-sized silver sulfadiazine ( mSSD) topical gel composed of Aloe vera gel ( Aloe gel) and Carbopol 940 for the management of second-degree burn wound. The optimized concentration of gel-forming agent (Carbopol 940) was chosen based on best possible consistency and spreadability of the gel. The second-degree burn infliction was developed in the posterior region of rats followed by anesthesia...
August 16, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30012032/challenges-for-migrant-and-cross-border-populations-with-diabetes-mellitus-at-mae-tao-clinic-in-the-mae-sot-myawaddy-border-region-of-thailand-and-myanmar
#14
Arkar Linn Naing, Menno Bakker
The Mae Tao Clinic was established by Dr Cynthia Maung in 1989 in Mae Sot, Thailand, close to the border with Myanmar. The clinic provides primary health care, education, and protection to vulnerable and displaced people living in the Thailand-Myanmar border area. The leading vision of the organization is that all people from Burma (Myanmar) will have access to quality, equitable, and affordable health care, education, and protection in respect of all human rights. On yearly basis, the Mae Tao Clinic consults more than 100 000 outpatients and admits more than 10 000 patients to receive inpatient care...
July 1, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30012070/pressure-ulcers-risk-stratification-and-prognostic-factors-that-promote-recurrence-after-reconstructive-surgery
#15
Wimon Sirimaharaj, Chirakan Charoenvicha
The aim of this study was to identify overall recurrence rates after reconstructive surgery in patients with pressure ulcers and to identify risk factors that associated with recurrence after reconstructive surgery. This study was done in Faculty of Medicine Chiang Mai University, including recurrence at the same site as well as on new sites, between January 1998 and December 2015. 165 patients with 272 pressure ulcers were retrospectively collected and analyzed. The overall pressure ulcer recurrence rate was 16...
June 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30012069/high-resolution-spectral-analysis-accurately-identifies-the-bacterial-signature-in-infected-chronic-foot-ulcers-in-people-with-diabetes
#16
Sridhar Poosapadi Arjunan, Aye Nyein Tint, Behzad Aliahmad, Dinesh Kant Kumar, Ravi Shukla, Julie Miller, Jeffrey D Zajac, Gayathiri Wang, Rekha Viswanathan, Elif Ilhan Ekinci
Diabetic foot infections are a major cause of hospitalization, and delayed treatment can lead to numerous complications. The aim of this research was to investigate high-resolution spectroscopy of the wound center and periwound area for real-time estimation of multispectral signature of bacteria at the base of diabetic foot ulcers. We investigated the spectrum of the reflected visual light from diabetic foot ulcers and developed a method that identifies the presence of bacteria in the wound infections. We undertook a prospective pilot study on 18 patients with type 1 and type 2 diabetes and chronic diabetic foot ulcers...
June 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30012068/speed-against-fidelity-of-communications-a-battle-for-editors
#17
Kittipan Rerkasem, Massimo Papi, Raj Mani
No abstract text is available yet for this article.
June 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30012067/evaluation-of-wound-dressing-made-from-spider-silk-protein-using-in-a-rabbit-model
#18
Zahra Setooni, Mostafa Mohammadi, Arman Hashemi, Mohammad Hashemi, Fateme Mozafari, Fateme Simi, Afshar Bargahi, Adel Daneshi, Mohammad Reza Hajiani-E-Asl, Parviz Farzadinia
The aim of the present article was to study the healing of wounds using spider silk. Eight New Zealand female rabbits were selected as animal model. First, 3 identical wounds with length of 15 mm and a depth of 4 mm on the back of each rabbit were created. The first group, as standard control, did not receive any special treatment, they were treated only with saline and Vaseline locally. The second group, as positive control, received a thin film of phenytoin 1% ointment locally. The third group, as treated group, received a thin film of spider silk protein...
June 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30012065/a-foreign-body-through-the-shoe-of-a-person-with-diabetic-peripheral-neuropathy-alters-contralateral-biomechanics-captured-through-innovative-plantar-pressure-technology
#19
Katie E Chatwin, Caroline A Abbott, Prabhav N Reddy, Frank L Bowling, Andrew J M Boulton, Neil D Reeves
High plantar pressure as a result of diabetic peripheral neuropathy is often reported as a major risk factor for ulceration. However, previous studies are confined to laboratories with equipment limited by cables, reducing the validity of measurements to daily life. The participant concerned in this case report was wearing an innovative plantar pressure feedback system as part of a wider study. The system allows for continuous plantar pressure monitoring and provides feedback throughout all activities of daily living...
June 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/29974798/malaysian-team-awarded-the-who-dr-lee-jong-wook-memorial-prize-for-public-health
#20
Harikrishna K R Nair
No abstract text is available yet for this article.
June 2018: International Journal of Lower Extremity Wounds
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