Ammara Saleem, Maira Javaid, Muhammad Furqan Akhtar, Ali Sharif, Bushra Akhtar, Muhammad Naveed, Uzma Saleem, Mirza Muhammad Faran Ashraf Baig, Hafiz Muhammad Zubair, Talha Bin Emran, Mohammad Saleem, Ghulam Md Ashraf
BACKGROUND: MicroRNAs (miRNA) are small noncoding RNAs that play a significant role in the regulation of gene expression. The literature has explored the key involvement of miRNAs in the diagnosis, prognosis, and treatment of various neurodegenerative diseases (NDD), such as Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD). The miRNA regulates various signalling pathways; its dysregulation is involved in the pathogenesis of NDD. OBJECTIVE: The present review is focused on the involvement of miRNAs in the pathogenesis of NDD and their role in the treatment or management of NDD...
October 12, 2023: Current Gene Therapy