journal
MENU ▼
Read by QxMD icon Read
search

Nature Reviews. Drug Discovery

journal
https://www.readbyqxmd.com/read/28799547/immunotherapy-car-t-cells-in-glioblastoma
#1
Crunkhorn Sarah
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28799546/antibacterial-agents-new-routes-to-tuberculosis-treatment
#2
Sarah Crunkhorn
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28799545/cancer-inhibiting-rock-in-neuroblastoma
#3
Crunkhorn Sarah
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28799544/cancer-immunotherapy-searching-in-the-immune-checkpoint-black-box
#4
M Teresa Villanueva
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28799543/systems-medicine-understanding-wellness-and-disease
#5
Crunkhorn Sarah
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28799542/regulatory-watch-structural-and-procedural-characteristics-of-international-regulatory-authorities
#6
Anand B Jain, Annette Mollet, Thomas D Szucs
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28799541/anticancer-agents-fighting-resistance
#7
Crunkhorn Sarah
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28775338/nih-centers-for-accelerated-innovations-program-principles-practices-successes-and-challenges
#8
Elliott M Antman, Paul E Di Corleto, Mason W Freeman, Tomas Ganz, David E Golan, Roger Kitterman, Joseph Loscalzo, Mark Low, Erin McKenna, Alan C O'Connor, Michael Palazzolo, John Parrish, Ofer Reizes, Robert S Ross, Cheryl Vaughan, D Geoffrey Vince, Lesley Watts
No abstract text is available yet for this article.
August 4, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28729727/senescent-cells-an-emerging-target-for-diseases-of-ageing
#9
REVIEW
Bennett G Childs, Martina Gluscevic, Darren J Baker, Remi-Martin Laberge, Dan Marquess, Jamie Dananberg, Jan M van Deursen
Chronological age represents the single greatest risk factor for human disease. One plausible explanation for this correlation is that mechanisms that drive ageing might also promote age-related diseases. Cellular senescence, which is a permanent state of cell cycle arrest induced by cellular stress, has recently emerged as a fundamental ageing mechanism that also contributes to diseases of late life, including cancer, atherosclerosis and osteoarthritis. Therapeutic strategies that safely interfere with the detrimental effects of cellular senescence, such as the selective elimination of senescent cells (SNCs) or the disruption of the SNC secretome, are gaining significant attention, with several programmes now nearing human clinical studies...
July 21, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28729726/heart-regeneration-and-repair-after-myocardial-infarction-translational-opportunities-for-novel-therapeutics
#10
REVIEW
Thomas J Cahill, Robin P Choudhury, Paul R Riley
Current therapies for heart failure after myocardial infarction are limited and non-curative. Although regenerative approaches are receiving significant attention, clinical efforts that involve transplantation of presumed stem and progenitor cells have largely failed to deliver. Recent studies of endogenous heart regeneration in model organisms, such as zebrafish and neonatal mice, are yielding mechanistic insights into the roles of cardiomyocyte proliferation, resident stem cell niches, neovascularization, the immune system and the extracellular matrix...
July 21, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28706220/opportunities-for-therapeutic-antibodies-directed-at-g-protein-coupled-receptors
#11
REVIEW
Catherine J Hutchings, Markus Koglin, William C Olson, Fiona H Marshall
G-protein-coupled receptors (GPCRs) are activated by a diverse range of ligands, from large proteins and proteases to small peptides, metabolites, neurotransmitters and ions. They are expressed on all cells in the body and have key roles in physiology and homeostasis. As such, GPCRs are one of the most important target classes for therapeutic drug discovery. The development of drugs targeting GPCRs has therapeutic value across a wide range of diseases, including cancer, immune and inflammatory disorders as well as neurological and metabolic diseases...
July 14, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28685764/market-watch-strategies-for-biosimilars-in-emerging-markets
#12
Ajay Gautam
No abstract text is available yet for this article.
July 7, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28685763/what-is-the-right-amount-to-spend-on-biopharma-r-d
#13
Michael S Ringel
No abstract text is available yet for this article.
July 7, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28685761/remyelination-therapies-a-new-direction-and-challenge-in-multiple-sclerosis
#14
REVIEW
Jason R Plemel, Wei-Qiao Liu, V Wee Yong
Multiple sclerosis is characterized by inflammatory activity that results in destruction of the myelin sheaths that enwrap axons. The currently available medications for multiple sclerosis are predominantly immune-modulating and do not directly promote repair. White matter regeneration, or remyelination, is a new and exciting potential approach to treating multiple sclerosis, as remyelination repairs the damaged regions of the central nervous system. A wealth of new strategies in animal models that promote remyelination, including the repopulation of oligodendrocytes that produce myelin, has led to several clinical trials to test new reparative therapies...
July 7, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28642610/the-multiple-sclerosis-market
#15
Anders Westad, Aditya Venugopal, Eric Snyder
No abstract text is available yet for this article.
June 23, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28620177/market-watch-upcoming-market-catalysts-in-q3-2017
#16
Sonny Nghiem
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28620176/g-protein-coupled-receptors-crystal-structure-of-glucagon-family-receptors
#17
Sarah Crunkhorn
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28620175/ageing-old-bone-removal
#18
M Teresa Villanueva
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28620173/cancer-targeting-myc-driven-translation
#19
Sarah Crunkhorn
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/28620172/endocrinology-reducing-fat-and-building-bone
#20
Sarah Crunkhorn
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Drug Discovery
journal
journal
39817
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"