journal
https://read.qxmd.com/read/38153610/a-review-of-pollen-counting-networks-from-the-nineteenth-century-into-the-twenty-first-century
#21
REVIEW
Richard W Lucas, Landon Bunderson
PURPOSE OF REVIEW: Pollen is enormously important to the human experience. As pollen became germane to human health in the late nineteenth century, methods for pollen collection and measurement were developed. Techniques were standardized and pollen counting networks were established in many parts of the world during the middle to late part of the twentieth century. With some notable exceptions, the technology of the 1950s and 1960s is presently employed to create the current pollen counting networks...
December 28, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/38085499/remission-in-type-2-inflammatory-diseases-current-evidence-unmet-needs-and-suggestions-for-defining-remission-in-chronic-rhinosinusitis-with-nasal-polyps
#22
REVIEW
Marco Caminati, Eugenio De Corso, Giancarlo Ottaviano, Carlotta Pipolo, Michele Schiappoli, Veronica Seccia, Francesca Romana Spinelli, Edoardo Vincenzo Savarino, Paolo Gisondi, Gianenrico Senna
PURPOSE OF REVIEW: The development of biological therapies for type 2 inflammatory diseases raises the possibility of addressing remission in those dis-immune conditions. No consensus exists for a definition of remission in chronic rhinosinusitis with nasal polyps (CRSwNP). This review aims to critically evaluate the published data to provide the basis for defining remission in CRSwNP. RECENT FINDINGS: The published evidence has yet to provide an unequivocal definition on remission in type 2 inflammatory diseases, in part reflecting differences in approaches to diagnosis and follow-up...
December 12, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/38064133/biomarkers-of-autoimmune-chronic-spontaneous-urticaria
#23
REVIEW
Désirée Larenas-Linnemann
PURPOSEOF REVIEW: Chronic spontaneous urticaria and chronic inducible urticaria (CSU/CindU) are caused by mast cell and basophil activation leading to degranulation and the release of histamine and several other mediators. Three kinds of factors can trigger mast cells in CSU: (1) activation of stimulating receptor(s) on the mast cell membrane, (2) upregulation of certain receptor(s), and (3) intracellular dysregulation in signaling with overexpression of the spleen tyrosine kinase (SYK) or reduced activation of the inhibitory Src homology 2 (SH2)-containing inositol phosphatases (SHIP)-related pathways...
December 8, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/38047993/the-impact-of-ambient-and-wildfire-air-pollution-on-rhinosinusitis-and-olfactory-dysfunction
#24
REVIEW
Sophie E Yu, Tejas S Athni, Margaret B Mitchell, Xiaodan Zhou, Simon Chiang, Stella E Lee
PURPOSE OF REVIEW: With increasing industrialization, exposure to ambient and wildfire air pollution is projected to increase, necessitating further research to elucidate the complex relationship between exposure and sinonasal disease. This review aims to summarize the role of ambient and wildfire air pollution in chronic rhinosinusitis (CRS) and olfactory dysfunction and provide a perspective on gaps in the literature. RECENT FINDINGS: Based on an emerging body of evidence, exposure to ambient air pollutants is correlated with the development of chronic rhinosinusitis in healthy individuals and increased symptom severity in CRS patients...
December 4, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/38038879/effects-of-endoscopic-sinus-surgery-on-olfactory-function
#25
REVIEW
L Stefano Ramirez-Gil, J J Ley-Tomas, J C Hernaiz-Leonardo, Isam Alobid, Joaquim Mullol, J C Ceballos-Cantu
PURPOSE OF REVIEW: To review the effects of endoscopic sinus surgery and endonasal approaches to the skull base on olfaction. RECENT FINDINGS: Advancements in endonasal endoscopic approaches to the sinuses and skull base allow for direct treatment of a variety of sinonasal and skull base diseases. However, these extended approaches will often require manipulation of normal anatomical structures and the olfactory neuroepithelium. Depending on the planned procedure and extent of disease, the prognosis of olfactory perception can vary significantly among patients...
December 1, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37995018/treatments-of-epistaxis-in-hereditary-hemorrhagic-telangiectasia-systematic-review-and-network-meta-analysis
#26
REVIEW
Wirach Chitsuthipakorn, Minh P Hoang, Dichapong Kanjanawasee, Kachorn Seresirikachorn, Kornkiat Snidvongs
PURPOSE OF REVIEW: To analyze and compare the effects of epistaxis treatments for Hereditary Hemorrhagic Telangiectasia (HHT) patients. RECENT FINDINGS: Of total of 21 randomized controlled trials (RCT), the data from 15 RCTs (697 patients, 7 treatments: timolol, propranolol, bevacizumab, doxycycline, tacrolimus, estriol/estradiol, and tranexamic acid) were pooled for the meta-analyses while the other 6 studies (treatments: electrosurgical plasma coagulation, KTP laser, postoperative packing, tamoxifen, sclerosing agent, and estriol) were reviewed qualitatively...
November 23, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37991673/endoscopic-extended-sinus-surgery-for-patients-with-severe-chronic-rhinosinusitis-with-nasal-polyps-the-choice-of-mucoplasty-a-systematic-review
#27
REVIEW
Daniel Martin-Jimenez, Ramon Moreno-Luna, Alfonso Cuvillo, Jaime Gonzalez-Garcia, Juan Maza-Solano, Serafin Sanchez-Gomez
PURPOSE OF REVIEW: The advances in the knowledge of the molecular basis of the inflammatory response in chronic rhinosinusitis with nasal polyps (CRSwNP) have led the management of these patients towards personalized and precision medicine. Surgery has been positioned as a suitable alternative in patients who do not achieve control with appropriate medical treatment, but polypoid recurrences remain a constraint. The emergence of new surgical approaches based on patient phenotyping and the poor disease control associated with type 2 inflammatory phenotype makes it necessary to review the role of personalized and precision surgery in managing the disease...
November 22, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37991672/expert-consensus-on-saba-use-for-asthma-clinical-decision-making-a-delphi-approach
#28
REVIEW
Njira Lugogo, Maeve O'Connor, Maureen George, Rajan Merchant, Greg Bensch, Jay Portnoy, John Oppenheimer, Mario Castro
PURPOSE OF REVIEW: A modified Delphi process was undertaken to provide a US expert-led consensus to guide clinical action on short-acting beta2 -agonist (SABA) use. This comprised an online survey (Phase 1), forum discussion and statement development (Phase 2), and statement adjudication (Phase 3). RECENT FINDINGS: In Phase 1 (n = 100 clinicians), 12% routinely provided patients with ≥4 SABA prescriptions/year, 73% solicited SABA use frequency at every patient visit, and 21% did not consult asthma guidelines/expert reports...
November 22, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37987873/type-2-biomarkers-for-the-indication-and-response-to-biologics-in-crswnp
#29
REVIEW
Cui-Lian Guo, Fei-Fan Liu, De-Yun Wang, Zheng Liu
PURPOSE OF REVIEW: Three biologics targeting type 2 inflammation have been approved for the treatment of severe and uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP). Nevertheless, around 40-60% of patients do not respond well to these biological treatments. Selecting appropriate patients is crucial to improve treatment outcome of biologics. This review summarizes the literature data on type 2 biomarkers, with a specific focus on the indication to biologics for severe CRSwNP...
November 21, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37934391/an-emerging-role-of-extracellular-traps-in-chronic-rhinosinusitis
#30
REVIEW
Siyuan Zhang, Zhenlin Wang
PURPOSE OF REVIEW: Chronic rhinosinusitis (CRS) is a complicated, heterogeneous disease likely caused by inflammatory and infectious factors. There is clear evidence that innate immune cells, including neutrophils and eosinophils, play a significant role in CRS. Multiple immune cells, including neutrophils and eosinophils, have been shown to release chromatin and granular proteins into the extracellular space in response to triggering extracellular traps (ETs). The formation of ETs remains controversial due to their critical function during pathogen clearance while being associated with harmful inflammatory illnesses...
November 7, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37889429/neuromyelitis-optica-pathogenesis-overlap-with-other-autoimmune-diseases
#31
REVIEW
Nadim Taheri, Julie Sarrand, Muhammad S Soyfoo
PURPOSE OF REVIEW: Neuromyelitis optica (NMO) is an auto-immune disease essentially depicted by optic neuritis and transverse myelitis. Per se, NMO was initially believed to be a sub-type of multiple sclerosis with typical demyelinating cerebral lesions and optic nerve inflammation. More recently, corroborating lignes of evidence have strengthened the concept of the spectrum of diseases associated with NMO and more specifically with the role of anti-aquaporin-4 antibodies in the pathogenesis of disease...
November 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37804376/overview-and-current-advances-in-dapsone-hypersensitivity-syndrome
#32
REVIEW
Zhen-Zhen Wang, Rui Zeng, Zi-Wei Wu, Chen Wang, Hai-Qin Jiang, Hong-Sheng Wang
PURPOSE OF REVIEW: As a sulfone antibacterial agent, dapsone has been widely used to treat leprosy. Moreover, dapsone is also used in many immune diseases such as herpetic dermatitis because of its anti-inflammatory and immunomodulatory effects. However, dapsone can cause several adverse effects, the most serious being dapsone hypersensitivity syndrome. Dapsone hypersensitivity syndrome is characterized by a triad of eruptions, fever, and organ involvement, which limits the application of dapsone to some extent...
October 7, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37644255/omalizumab-treatment-in-uncontrolled-asthma-and-crswnp-patients-with-previous-endoscopic-sinus-surgery-to-improve-quality-of-life-and-endoscopic-outcomes-a-two-year-real-life-study
#33
REVIEW
Juan Maza-Solano, Amparo Callejon-Leblic, Daniel Martin-Jimenez, Ramon Moreno-Luna, Jaime Gonzalez-Garcia, Alfonso Cuvillo, Serafin Sanchez-Gomez
PURPOSE OF REVIEW: Despite molecular underlying advances, limited and divergent data on monoclonal antibodies (mAb) therapy in chronic rhinosinusitis with nasal polyps (CRSwNP) make further analysis necessary. The objective of this study is to evaluate the effect of omalizumab as an adjunct to endoscopic sinus surgery (ESS) on the treatment of CRSwNP under real-life conditions. RECENT FINDINGS: Since the introduction of omalizumab, as the first biologic agent for the treatment of diseases such as severe allergic asthma, different studies have demonstrated an effect of omalizumab on CRSwNP, with significant improvements in sinonasal symptoms and endoscopic scores...
October 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37665560/allergen-stability-in-food-allergy-a-clinician-s-perspective
#34
REVIEW
Larissa Koidl, Salvatore Alessio Gentile, Eva Untersmayr
PURPOSE OF REVIEW: The globally rising food allergy prevalence is associated with the urgent need for new disease prevention methods, efficient treatment, and reliable risk assessment methods for characterization of food allergens. Due to inter-individual variations in the digestive system, food allergens are degraded to a different extent in each person. Food processing also influences allergen digestion. RECENT FINDINGS: In this review, we provide an overview of the digestive system with focus on relevance for food allergy...
September 4, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37402064/multiple-sclerosis-pathogenesis-and-updates-in-targeted-therapeutic-approaches
#35
REVIEW
Eleni S Vasileiou, Kathryn C Fitzgerald
PURPOSE OF REVIEW: In this review, we provide a comprehensive update on current scientific advances and emerging therapeutic approaches in the field of multiple sclerosis. RECENT FINDINGS: Multiple sclerosis (MS) is a common disorder characterized by inflammation and degeneration within the central nervous system (CNS). MS is the leading cause of non-traumatic disability in the young adult population. Through ongoing research, an improved understanding of the disease underlying mechanisms and contributing factors has been achieved...
September 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37651001/effects-of-allergen-exposure-and-environmental-risk-factors-in-schools-on-childhood-asthma
#36
REVIEW
Eva Yarsky, Tina M Banzon, Wanda Phipatanakul
PURPOSE OF REVIEW: This review aims to assess the prevalence of common allergen exposures and environmental risk factors for asthma in schools, examine the underlying mechanisms of these environmental risk factors, and explore possible prevention strategies. RECENT FINDINGS: Cockroach, mouse, dust mites, fungi, viral infections, ozone pollution, and cleaning products are common allergen exposures and environmental risk factors in schools which may affect asthma morbidity...
August 31, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37610671/the-role-of-iga-in-the-manifestation-and-prevention-of-allergic-immune-responses
#37
REVIEW
Stephan Scheurer, Ann-Christine Junker, Chaoqi He, Stefan Schülke, Masako Toda
PURPOSE OF REVIEW: Immunoglobulin A (IgA) mediates immune exclusion of antigens in the gut. Notably, IgA plays also a role in the prevention of IgE-mediated allergies and induction of immune tolerance. The present review addresses the role of IgA in the manifestation of IgE-mediated allergies, including allergen-specific immunotherapy (AIT), the regulation of IgA production, and the mechanism of IgA in immune cell activation. RECENT FINDINGS: The majority of studies report an association of IgA with the induction of immune tolerance in IgE-mediated allergies...
August 23, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37561310/management-of-mechanical-nasal-obstruction-isolated-or-associated-to-upper-airway-inflammatory-diseases-in-real-life-use-of-both-subjective-and-objective-criteria
#38
REVIEW
Carla Merma-Linares, M Dolores Martinez, Miriam Gonzalez, Isam Alobid, Enric Figuerola, Joaquim Mullol
PURPOSE OF REVIEW: Mechanical nasal obstruction (MNO) is a prevalent condition with a high impact on patient's quality-of-life (QoL) and socio-economic burden. The aim of this study was to determine the usefulness of both subjective and objective criteria in the appropriate management of MNO, either alone or associated to upper airway inflammatory diseases such as allergic rhinitis (AR) or chronic rhinosinusitis with nasal polyps (CRSwNP). RECENT FINDINGS: A long debate persists about the usefulness of subjective and objective methods for making decisions on the management of patients with nasal obstruction...
August 10, 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37436637/autoimmune-inflammatory-eye-disease-demystifying-clinical-presentations-for-the-internist
#39
REVIEW
Richmond Woodward, Sri Meghana Konda, Dilraj S Grewal
PURPOSE OF REVIEW: Provide a framework for recognizing key symptoms and clinical findings in patients with autoimmune inflammatory eye disease. RECENT FINDINGS: The most common manifestations of autoimmune inflammatory eye disease are episcleritis, scleritis, uveitis (anterior, intermediate, posterior, and panuveitis), and keratoconjunctivitis sicca. Etiologies can be idiopathic or in association with a systemic autoimmune condition. Referral of patients who may have scleritis is critical for patients presenting with red eyes...
August 2023: Current Allergy and Asthma Reports
https://read.qxmd.com/read/37452992/occupational-rhinitis-an-update
#40
REVIEW
Jose Zamora-Sifuentes, Jill A Poole
PURPOSE OF REVIEW: Occupational rhinitis is an underdiagnosed disease with significant morbidity and implications in the workplace. Multiple factors associated with this disease continue to pose a challenge to investigators. This review aims to summarize recent literature in occupational rhinitis, including classifications, pathogenesis, diagnosis, and treatment, as well as the impact of occupational rhinitis on individuals. Additionally, it identifies areas in need of further research and investigation...
July 15, 2023: Current Allergy and Asthma Reports
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