journal
MENU ▼
Read by QxMD icon Read
search

Current Allergy and Asthma Reports

journal
https://www.readbyqxmd.com/read/29749587/newborn-screening-for-severe-combined-immunodeficiency
#1
REVIEW
John Routes, James Verbsky
PURPOSE OF REVIEW: This review provides a brief history of newborn screening (NBS) for severe combined immunodeficiency (SCID), discusses the theoretical basis for the T cell receptor excision circle (TREC) assay, highlights the results of recent studies using the TREC, and provides practical advice for the evaluation of infants with an abnormal TREC assay. RECENT FINDINGS: Currently, all but three states perform NBS for SCID in the USA. NBS using the TREC assay is highly sensitive in identifying infants with SCID and may also identify infants with T cell lymphopenia due to other causes such as congenital syndromes, multiple congenital anamolies, and some combined immunodeficiencies...
May 10, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29748919/severe-atopic-dermatitis-in-children
#2
REVIEW
Evie Huang, Peck Y Ong
PURPOSE OF REVIEW: Severe atopic dermatitis (AD) in childhood leads to significant morbidity including psychosocial problems and infectious complications. There are only a few approved treatment options for these patients. These include topical corticosteroids and tacrolimus ointment, which are associated with potential side effects. RECENT FINDINGS: In order to find better and safer treatments, further understanding of AD mechanisms is needed. Primary skin barrier defects play an important role in the pathogenesis of AD...
May 10, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29744661/update-on-omalizumab-for-urticaria-what-s-new-in-the-literature-from-mechanisms-to-clinic
#3
REVIEW
Désirée E S Larenas-Linnemann, Claudio A S Parisi, Carla Ritchie, Ricardo Cardona-Villa, Ivan Cherrez-Ojeda, Annia Cherrez, Luis Felipe Ensina, Elizabeth Garcia, Iris V Medina, Mónica Rodríguez-González, Jorge Mario Sánchez Caraballo
PURPOSE OF REVIEW: Since omalizumab has been approved for urticaria, numerous randomized and real-life observational trials have been published. We reviewed the period January 2017-February 2018. RECENT FINDINGS: Omalizumab is effective for the control of urticaria recalcitrant to antihistamines in different populations globally. The ratio of total serum IgE 4-week/baseline ≥2 can predict response with a high likelihood. In observational real-life trials, doses have been adjusted on an individual basis: in some populations, up to two-thirds of the patients can be controlled with 150 mg/month; however, others are still not controlled with 300 mg/month...
May 9, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29696417/sinus-and-upper-airway-surgery-in-children
#4
REVIEW
Chadi A Makary, Hassan H Ramadan
PURPOSE OF REVIEW: Chronic sinus and upper airway disease in children is a common health problem encountered every day. Its pathophysiology is complicated which leads to different treatment options and approaches. We seek to review the current literature and evidence to surgical treatments. RECENT FINDINGS: Medical treatment with antibiotics and topical nasal sprays continues to be the first-line treatment. Surgical interventions include adenoidectomy, balloon catheter sinuplasty (BCS), and endoscopic sinus surgery (ESS)...
April 25, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29680987/slit-s-prevention-of-the-allergic-march
#5
REVIEW
Federica Porcaro, Giovanni Corsello, Giovanni Battista Pajno
PURPOSE OF REVIEW: The progression of atopic disorders from atopic dermatitis in infants to allergic rhinitis and asthma in children, adolescents, and adults defines the allergy march. Allergen immunotherapy is the only causal treatment altering the immunological mechanism underlying the allergic diseases. The sublingual administration route is more acceptable than the subcutaneous one in pediatric age. RECENT FINDINGS: Several studies show the efficacy and safety profile of sublingual immunotherapy (SLIT) for the treatment of respiratory allergy diseases, but few data are available on its effect of primary and secondary prevention of allergic disease...
April 21, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29667026/mast-cell-interactions-and-crosstalk-in-regulating-allergic-inflammation
#6
REVIEW
Tania E Velez, Paul J Bryce, Kathryn E Hulse
PURPOSE OF REVIEW: This review summarizes recent findings on mast cell biology with a focus on IgE-independent roles of mast cells in regulating allergic responses. RECENT FINDINGS: Recent studies have described novel mast cell-derived molecules, both secreted and membrane-bound, that facilitate cross-talk with a variety of immune effector cells to mediate type 2 inflammatory responses. Mast cells are complex and dynamic cells that are persistent in allergy and are capable of providing signals that lead to the initiation and persistence of allergic mechanisms...
April 17, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29663154/ambient-air-pollution-and-asthma-related-outcomes-in-children-of-color-of-the-usa-a-scoping-review-of-literature-published-between-2013-and-2017
#7
REVIEW
Anthony Nardone, Andreas M Neophytou, John Balmes, Neeta Thakur
PURPOSE OF REVIEW: Given racial disparities in ambient air pollution (AAP) exposure and asthma risk, this review offers an overview of the literature investigating the ambient air pollution-asthma relationship in children of color between 2013 and 2017. RECENT FINDINGS: AAP is likely a key contributor to the excess burden of asthma in children of color due to pervasive exposure before birth, at home, and in school. Recent findings suggest that psychosocial stressors may modify the relationship between AAP and asthma...
April 16, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29623454/food-protein-induced-enterocolitis-syndrome-fpies-review-of-recent-guidelines
#8
REVIEW
Sheeba Cherian, Pooja Varshney
PURPOSE OF REVIEW: To increase understanding of food protein-induced enterocolitis syndrome (FPIES), a non-immunoglobulin E (IgE)-mediated reaction to food, by reviewing a growing body of literature, including recently published international consensus guidelines. RECENT FINDINGS: FPIES primarily affects infants and young children and is characterized by the delayed onset of gastrointestinal symptoms, predominantly repetitive vomiting, in response to a trigger food...
April 6, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29623445/role-of-the-microbiome-in-food-allergy
#9
REVIEW
Hsi-En Ho, Supinda Bunyavanich
PURPOSE OF REVIEW: Resident microbial communities likely modify risk for allergic disorders, including food allergy. We review epidemiologic studies linking microbial exposures to food allergy risk and discuss the mechanisms by which the microbiome may modulate oral tolerance. We additionally address ongoing translational efforts in human microbiome studies. RECENT FINDINGS: Epidemiologic studies and murine models support that altered microbial exposures and colonization in early life modify food allergy risk...
April 5, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29574605/climate-change-and-the-impact-on-respiratory-and-allergic-disease-2018
#10
REVIEW
Jeffrey G Demain
PURPOSE OF REVIEW: The purpose of this paper is to review allergic respiratory disease related to indoor and outdoor exposures and to examine the impact of known and projected changes in climate. The global burden of disease directly attributed to climate change is very difficult to measure and becomes more challenging when the capacity of humans to adapt to these changes is taken into consideration. Allergic respiratory disease, such as asthma, is quite heterogenous, though closely associated with environmental and consequently immunologic interaction...
March 24, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29574586/precision-medicine-in-chronic-rhinosinusitis-with-nasal-polyps
#11
REVIEW
Klementina Avdeeva, Wytske Fokkens
PURPOSE OF REVIEW: Chronic rhinosinusitis is a disease with high prevalence, significant impact on health-related quality of life (HRQoL) and it is associated with substantial healthcare and productivity costs. We face an urgent need to improve the level of disease control and achieve higher patient satisfaction and disease prevention. Precision medicine is increasingly recognized as the way forward in optimal patient care. The combination of personalized care, prevention of disease, prediction of success of treatment, and participation of the patient in the elaboration of the treatment plan is expected to guarantee the best possible therapeutic approach for individuals suffering from a chronic disabling condition...
March 24, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29574562/severe-cutaneous-adverse-drug-reactions-presentation-risk-factors-and-management
#12
REVIEW
S Shahzad Mustafa, David Ostrov, Daniel Yerly
PURPOSE OF STUDY: Immune-mediated adverse drug reactions occur commonly in clinical practice and include mild, self-limited cutaneous eruptions, IgE-mediated hypersensitivity, and severe cutaneous adverse drug reactions (SCAR). SCARs represent an uncommon but potentially life-threatening form of delayed T cell-mediated reaction. The spectrum of illness ranges from acute generalized exanthematous pustulosis (AGEP) to drug reaction with eosinophilia with systemic symptoms (DRESS), to the most severe form of illness, Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)...
March 24, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29574559/how-do-storms-affect-asthma
#13
REVIEW
Gennaro D'Amato, Isabella Annesi-Maesano, Adriano Vaghi, Lorenzo Cecchi, Maria D'Amato
PURPOSE OF REVIEW: There are observations in various geographical areas that thunderstorms occurring during pollen seasons can induce severe asthma attacks in pollinosis patients. RECENT FINDINGS: An accredited hypothesis explaining the association between thunderstorms and asthma suggests that storms can concentrate pollen grains at ground level, which may then release allergenic particles of respirable size in the atmosphere after their imbibition of water and rupture by osmotic shock...
March 24, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29574527/treatment-of-allergic-rhinitis-as-a-strategy-for-preventing-asthma
#14
REVIEW
Jaymin B Morjaria, Massimo Caruso, Rosalia Emma, Cristina Russo, Riccardo Polosa
PURPOSE OF REVIEW: To evaluate the impact of allergic rhinitis (AR) on the development of asthma and to update readers on recent literature suggesting that early treatment of allergic subjects with immunotherapy may prevent asthma onset. RECENT FINDINGS: AR is frequently associated with asthma, leading to the concept that these two conditions are different aspects of the same disease. There is increasing evidence that AR precedes the onset of asthmatic symptoms and current treatment strategies are beneficial in symptom control with no impact prevention...
March 24, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29574493/immigrant-respiratory-health-a-diverse-perspective-in-environmental-influences-on-respiratory-health
#15
REVIEW
Andrea A Pappalardo, Giselle Mosnaim
PURPOSE OF REVIEW: The aim of this review is to examine the prevalence of and impact of environmental exposures in the workplace and home on immigrant respiratory health in the USA. RECENT FINDINGS: Few studies report levels of workplace and home environmental exposures for immigrant children and adults, and documenting these findings is an important first step to addressing their respiratory health concerns. Rates of respiratory disease are lowest upon first arrival and increase with duration of residency in the USA...
March 24, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29557517/do-glutathione-s-transferase-genes-modify-the-link-between-indoor-air-pollution-and-asthma-allergies-and-lung-function-a-systematic-review
#16
REVIEW
Xin Dai, Gayan Bowatte, Adrian J Lowe, Melanie C Matheson, Lyle C Gurrin, John A Burgess, Shyamali C Dharmage, Caroline J Lodge
PURPOSE OF REVIEW: Glutathione S-transferase (GST) genes are involved in oxidative stress management and may modify the impact of indoor air pollution. We aimed to assess the influence of GST genes on the relationship between indoor air pollution and allergy/lung function. RECENT FINDINGS: Our systematic review identified 22 eligible studies, with 15 supporting a gene-environment interaction. Carriers of GSTM1/T1 null and GSTP1 val genotypes were more susceptible to indoor air pollution exposures, having a higher risk of asthma and lung function deficits...
March 20, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29470720/diagnostic-tools-for-inborn-errors-of-human-immunity-primary-immunodeficiencies-and-immune-dysregulatory-diseases
#17
REVIEW
Annely M Richardson, Ann M Moyer, Linda Hasadsri, Roshini S Abraham
PURPOSE OF REVIEW: The purpose of this review is to provide an overview of diagnostic testing in primary immunodeficiency and immune dysregulatory disorders (PIDDs), particularly focusing on flow cytometry and genetic techniques, utilizing specific examples of PIDDs. RECENT FINDINGS: Flow cytometry remains a vital tool in the diagnosis and monitoring of immunological diseases. Its utility ranges from cellular analysis and specific protein quantitation to functional assays and signaling pathway analysis...
February 22, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29470668/indoor-environmental-interventions-and-their-effect-on-asthma-outcomes
#18
REVIEW
Rebin Kader, Kevin Kennedy, Jay M Portnoy
PURPOSE OF REVIEW: The use of environmental interventions to improve outcomes in asthmatics has long been an elusive goal. While numerous interventions have been studied, the results of clinical trials have been mixed. This review aims to identify combinations of interventions that have been proven to be effective and to propose a model for using them in a clinical setting. RECENT FINDINGS: An NIH workshop emphasized a need for research to identify effective interventions for reducing indoor exposures and improving asthma outcomes...
February 22, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29470661/granulomatous-lymphocytic-interstitial-lung-disease-in-22q11-2-deletion-syndrome-a-case-report-and-literature-review
#19
REVIEW
Amika K Sood, William Funkhouser, Brian Handly, Brent Weston, Eveline Y Wu
PURPOSE OF REVIEW: Granulomatous-lymphocytic interstitial lung disease (GLILD) has classically been associated with common variable immune deficiency (CVID), but is increasingly being reported in other immunodeficiencies. We describe the second reported case of GLILD in a patient with 22q11.2 deletion syndrome (22q11.2DS) and review the recent literature surrounding GLILD. RECENT FINDINGS: GLILD is characterized by granulomata and lymphoproliferation. Consensus statements and retrospective and case-control studies have better elucidated the clinicopathological and radiographic manifestations of GLILD, allowing for its differentiation from similar conditions like sarcoidosis...
February 22, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29470660/the-effect-of-inhalant-organic-dust-on-bone-health
#20
REVIEW
Joseph M Carrington, Jill A Poole
PURPOSE OF REVIEW: Agriculture remains a major economic sector globally, and workers experience high rates of chronic inflammatory lung and musculoskeletal diseases. Whereas obstructive pulmonary diseases are known risk factors for bone loss, the underlying relationship between lung inflammation and bone health is not well known. RECENT FINDINGS: An agriculture organic dust extract inhalation animal model has recently linked lung injury-induced inflammation to systemic bone loss...
February 22, 2018: Current Allergy and Asthma Reports
journal
journal
39682
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"