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Transfusion and Apheresis Science

Hamit Sirri Keten, Oguz Isik, Celal Kus, Ozgur Ersoy, Soner Olmez, Fatis Yildirim, Mustafa Celik
The aim of the present study was to determine knowledge level, attitudes, and behaviors of Islamic religious officials toward blood donation. This study included 334 religious officials rendering service in the province of Kahramanmaras, located in the Mediterranean region of Turkey. A questionnaire was administered to gather sociodemographic data of the participants and their knowledge levels, attitudes, and behaviors toward blood donation. The questionnaire consisted of 11 questions that yielded a total of 11 points...
November 2, 2017: Transfusion and Apheresis Science
Sukhi Singh, Caroline Shams Hakimi, Anders Jeppsson, Camilla Hesse
Platelet storage lesion is characterized by morphological changes and impaired platelet function. The collection method and storage medium may influence the magnitude of the storage lesion. The aim of this study was to compare the newly introduced interim platelet unit (IPU) platelet concentrates (PCs) (additive solution SSP+, 40% residual plasma content) with the more established buffy-coat PCs (SSP, 20% residual plasma content) and apheresis PCs (autologous plasma) in terms of platelet storage lesions. Thirty PCs (n=10 for each type) were assessed by measuring metabolic parameters (lactate, glucose, and pH), platelet activation markers, and in vitro platelet aggregability on days 1, 4, and 7 after donation...
November 2, 2017: Transfusion and Apheresis Science
Mariasanta Napolitano, Sergio Siragusa
Aging with rare bleeding disorders such as factor VII (FVII) deficiency poses several challenges to treatment because of the occurrence of cerebral and cardiovascular age-related comorbidities and high bleeding risks. We report a case of long-term treatment with antiplatelet agents and contemporary prophylaxis of bleeding in a woman affected by severe FVII deficiency diagnosed with symptomatic coronary artery stenosis. Information on the management of antithrombotic treatment in rare bleeding disorders is lacking and mainly limited to anecdotal reports or side effects secondary to replacement therapy...
November 1, 2017: Transfusion and Apheresis Science
Ryan P Jajosky, Audrey N Jajosky, Philip G Jajosky
No abstract text is available yet for this article.
October 20, 2017: Transfusion and Apheresis Science
Olga Ciepiela, Anna Jaworska, Dominika Łacheta, Natalia Falkowska, Katarzyna Popko, Urszula Demkow
BACKGROUND: Transfusion of blood-derived products is often used as a life-saving treatment, and being a blood donor should be common, especially among medical professionals. Thus, an awareness of one's own blood type in medical students should be common. Our aim was to assess if students of the Medical University of Warsaw know their blood type and how many of them are registered blood donors. MATERIAL AND METHODS: A survey was conducted in a group of 1121 students...
October 18, 2017: Transfusion and Apheresis Science
Garrett S Booth
No abstract text is available yet for this article.
October 16, 2017: Transfusion and Apheresis Science
Shabnam Asfaram, Mahdi Fakhar, Masoud Soosaraei, Saeed Hosseini Teshnizi, Ahmad Mardani, Elham Sadat Banimostafavi, Hajar Ziaei Hezarjaribi
INTRODUCTION: Transmission of Leishmania through transfusion has been reported from various Visceral leishmaniasis (VL) endemic areas of the world. The true burden of Leishmania infection in blood donors remains generally unknown. Thus, the present systematic review attempted to determine the global prevalence of Leishmania infection among blood donors. METHODS: Data were extracted through five English and five Persian databases during the period from 1997 to 2016...
September 21, 2017: Transfusion and Apheresis Science
Sara Alfieri
BACKGROUND: Scientific literature on blood donation is prevalently concentrated on adults, leaving out adolescents almost completely. While the latter represents "ideal" candidates, they constitute, however, the segment of the population least present among blood donors. OBJECTIVES: The present work, composed of two studies, proposes looking into the representations that the adolescents have of blood donation and give voice to the motivations that could persuade them to becoming donors once they reach the legal age for donation...
September 20, 2017: Transfusion and Apheresis Science
Ryu Yanagisawa, Seiki Abe, Ikuko Fujihara, Kazutoshi Komori, Yoshiaki Kondo, Kazuo Sakashita, Tomohiko Nakamura
BACKGROUND: Although several types of transfusion-related adverse reactions (TRARs) have been reported, one of the most important involves respiratory features during and after blood transfusion. Transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO) are the most severe adverse events following blood transfusion, whereas transfusion-associated dyspnea (TAD) is a less severe respiratory distress. However, there exists little evidence of these factors in pediatric populations...
September 20, 2017: Transfusion and Apheresis Science
Gail Rock
No abstract text is available yet for this article.
September 20, 2017: Transfusion and Apheresis Science
Ryan P Jajosky, Audrey N Jajosky, James F Shikle, Roni J Bollag
No abstract text is available yet for this article.
September 14, 2017: Transfusion and Apheresis Science
Li-Xin Jiao, Jing-Ying Zhang, Lin Chen, Xiao-Li Yu, Yu Han, Fan Yang, Jiang-Hong Yu, Ling-Ling Liu, Yue Lang
OBJECTIVE: To study serologic and gene characteristics of the B(A) blood group of blood donation volunteers in Jilin Province, China. METHODS: ABO subgroups were identified by standard serologic techniques in ABO typing discrepancy samples from all donors at the Jilin Blood Center (410,354 non-repeat donors). DNA (deoxyribonucleic acid) was collected from each sample and PCR (polymerase chain reaction) was used to sequence exons 6 and 7 and intron 6, part 5 from the ABO subgroup samples...
September 11, 2017: Transfusion and Apheresis Science
Shin-Ichiro Fujiwara, Shuichi Kino, Asashi Tanaka, Yuichi Hasegawa, Akihiko Yokohama, Keizo Fujino, Makino Shigeyoshi, Mayumi Matsumoto, Akihiro Takeshita, Kazuo Muroi
BACKGROUND: Premedication before transfusion is commonly administered in clinical practice despite a lack of evidence for its efficacy. The aim of this study was to clarify the status of premedication and evaluate expert opinions regarding its use in Japanese medical institutions. METHOD: Between May and July 2016, we conducted a questionnaire survey on premedication before transfusion in 252 medical institutes that were certified by an academic society or employed transfusion experts...
September 11, 2017: Transfusion and Apheresis Science
Ayse Esra Karakoc, Rukiye Berkem, Hasan Irmak, Ali Pekcan Demiroz, Idil Yenicesu, Nigar Ertugrul, Önder Arslan, Sabri Kemahli, Sevinc Yilmaz, Osman Ozcebe, Abdurrahman Kara, Gulsum Ozet, Ziya Cibali Acikgoz, Tulin Acikgoz
PURPOSE: In this study we aimed to propose an algorithm for initial anti HCV EIA reactive blood donations in Turkey where nucleic acid amplification tests are not yet obligatory for donor screening. METHODS: A total of 416 anti HCV screening test reactive donor samples collected from 13 blood centers from three cities in Turkey were tested in duplicate by Ortho HCV Ab Version 3.0 and Radim HCV Ab. All the repeat reactive samples were tested by INNO-LIA HCV Ab 3...
September 8, 2017: Transfusion and Apheresis Science
M Blaha, M Lanska, H Tomsova, P Zak
INTRODUCTION: The WAA Registry allows detailed registration of hemapheresis data. Our center registers results there as well. We summarize our results as compared to those of the WAA Registry. MATERIALS AND METHODS: Hemapheresis results are registered in the WAA Registry in Umea, Sweden. The patients' identity is protected by coding. General data (age, gender, weight, procedure, technique used etc.) or special data (occurrence and type of adverse reactions, health condition, quality of life etc...
September 6, 2017: Transfusion and Apheresis Science
Hidenori Matsuo
Apheresis therapy was first introduced into Japan from the United State as plasmapheresis by a centrifuge method. However, the invention of hollow fiber has subsequently lead to a membrane plasma separation. Selective removal of the plasma or cell component has been improved and matured in clinical application. Therapeutic apheresis has progressed and diversified with the development of technology for membrane separation by hollow fiber and adsorption with a physicochemical adsorbent in Japan.
September 5, 2017: Transfusion and Apheresis Science
Wenjing Zhang, Jinling Liu, Wei Zhang, Yunlong Zhuang
Patients with AML may show ABO blood typing discrepancy, and the expression levels of the ABO antigens may show some alterations with the disease progression. To better understand this phenomenon, the blood samples of 25 AML patients and 25 healthy blood donors were examined. The serological ABO blood types of the patients were determined in different AML stages, and gene sequencing was performed to identify the precise ABO genotypes. Reverse transcription-polymerase chain reaction (RT-PCR) was carried out to detect the transcription levels of the antigens...
September 1, 2017: Transfusion and Apheresis Science
Carmen Vicente-Ayuso, Petros Papadopoulos, María Villa-Fajardo, Blanca Prieto, Ana María Álvarez-Carmona, Marta Mateo-Morales, Cristina Pérez-López, Ascensión Peña-Cortijo, Marta Polo-Zarzuela, Isabel Sáez, María Paz Martín, Celina Benavente-Cuesta, Ataúlfo González-Fernández, Rafael Martínez-Martínez, Jaap Jan Zwaginga, Jerard Seghatchian, Laura Gutiérrez
Hemato-oncologic patients with chemotherapy-induced thrombocytopenia are one of the populations receiving platelet transfusions. The general practice with these patients is to give prophylactic platelet transfusions when platelet counts fall below 10×10(9)PLT/L. However, in more than 40% of these patients, platelet transfusion does not prevent bleeding. The reason of the low efficacy of platelet transfusion in the context of chemotherapy patients is not entirely understood. We therefore aimed at immunophenotyping the expression of platelet surface and activation markers and thrombopoietin levels from hemato-oncologic patients before and after transfusion...
August 31, 2017: Transfusion and Apheresis Science
Hisashi Makino, Tamiko Tamanaha, Mariko Harada-Shiba
LDL apheresis has been developed as the treatment for refractory familial hypercholesterolemia (FH). Currently, plasma exchange, double membrane filtration, and selective LDL adsorption are available in Japan, and selective LDL adsorption is most common method. LDL apheresis can prevent atherosclerosis progression even in homozygous (HoFH). However, in our observational study, HoFH who started LDL apheresis from adulthood had poor prognosis compared with patients who started from childhood. Therefore, as far as possible, HoFH patients need to start LDL apheresis from childhood...
August 31, 2017: Transfusion and Apheresis Science
Tsung-Jen Wang, Ming-Sheng Chen, Ming-Li Chou, Hsiu-Chen Lin, Jerard Seghatchian, Thierry Burnouf
BACKGROUND: Human platelet lysates (HPLs) are emerging as the new gold standard supplement of growth media for ex vivo expansion of cells for transplant. However, variations do exist in the way how HPLs are prepared. In particular, uncertainties still exist regarding the type of HPL most suitable for corneal endothelium cells (CEC) expansion, especially as these cells have limited proliferative capacity. MATERIAL AND METHODS: Three distinct HPL preparations were produced, with or without calcium chloride/glass beads activation, and with or without heat treatment at 56°C for 30min...
August 31, 2017: Transfusion and Apheresis Science
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