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Current Diabetes Reports

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https://www.readbyqxmd.com/read/28942594/keeping-up-with-the-diabetes-technology-2016-endocrine-society-guidelines-of-insulin-pump-therapy-and-continuous-glucose-monitor-management-of-diabetes
#1
REVIEW
Alfonso Galderisi, Elise Schlissel, Eda Cengiz
PURPOSE OF REVIEW: Decades after the invention of insulin pump, diabetes management has encountered a technology revolution with the introduction of continuous glucose monitoring, sensor-augmented insulin pump therapy and closed-loop/artificial pancreas systems. In this review, we discuss the significance of the 2016 Endocrine Society Guidelines for insulin pump therapy and continuous glucose monitoring and summarize findings from relevant diabetes technology studies that were conducted after the publication of the 2016 Endocrine Society Guidelines...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28942581/minimally-disruptive-medicine-for-patients-with-diabetes
#2
REVIEW
Valentina Serrano, Gabriela Spencer-Bonilla, Kasey R Boehmer, Victor M Montori
PURPOSE OF REVIEW: Patients with diabetes must deal with the burden of symptoms and complications (burden of illness). Simultaneously, diabetes care demands practical and emotional work from patients and their families, work to access and use healthcare and to enact self-care (burden of treatment). Patient work must compete with the demands of family, job, and community life. Overwhelmed patients may not have the capacity to access care or enact self-care and will thus experience suboptimal diabetes outcomes...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28942537/a-review-of-technology-assisted-interventions-for-diabetes-prevention
#3
REVIEW
Shira Grock, Jeong-Hee Ku, Julie Kim, Tannaz Moin
PURPOSE OF REVIEW: The high prevalence of prediabetes and success of the diabetes prevention program (DPP) has led to increasing efforts to provide readily accessible, cost-effective DPP interventions to the general public. Technology-assisted DPP interventions are of particular interest since they may be easier to widely distribute and sustain as compared to traditional in-person DPP. The purpose of this article is to provide an overview of currently available technology-assisted DPP interventions...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28942533/the-time-is-now-diabetes-fellowships-in-the-united-states
#4
REVIEW
Archana R Sadhu, Amber M Healy, Shivajirao P Patil, Doyle M Cummings, Jay H Shubrook, Robert J Tanenberg
PURPOSE OF REVIEW: Diabetes is a complex and costly chronic disease that is growing at an alarming rate. In the USA, we have a shortage of physicians who are experts in the care of patients with diabetes, traditionally endocrinologists. Therefore, the majority of patients with diabetes are managed by primary care physicians. With the rapid evolution in new diabetes medications and technologies, primary care physicians would benefit from additional focused and intensive training to manage the many aspects of this disease...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28942509/technology-interventions-to-manage-food-intake-where-are-we-now
#5
REVIEW
Margaret Allman-Farinelli, Luke Gemming
PURPOSE OF REVIEW: This review describes the state-of-the-art for dietary assessment using smartphone apps and digital technology and provides an update on the efficacy of technology-mediated interventions for dietary change. RECENT FINDINGS: Technology has progressed from apps requiring entry of foods consumed, to digital imaging to provide food intake data. However, these methods rely on patients being active in data collection. The automated estimation of the volume and composition of every meal consumed globally is years away...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28942507/physical-exercise-improves-heart-rate-variability-in-patients-with-type-2-diabetes-a-systematic-review
#6
REVIEW
Santos Villafaina, Daniel Collado-Mateo, Juan Pedro Fuentes, Eugenio Merellano-Navarro, Narcis Gusi
PURPOSE OF REVIEW: The aim of the present systematic review is to provide an up-to-date analysis of the research on the effects of exercise programs on heart rate variability (HRV) in individuals with type 2 diabetes mellitus (T2DM). An electronic search of the literature (PubMed, PEDro and Web of Science) was performed. "HRV", "heart rate variability", "exercise", "physical" and "diabetes" were the terms used for article retrieval. Lastly, 15 articles were selected. PRISMA methodology was employed and data were extracted according to the PICOS approach...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28942491/modulation-of-type-1-diabetes-risk-by-the-intestinal-microbiome
#7
REVIEW
Mikael Knip, Jarno Honkanen
PURPOSE OF REVIEW: The purpose of this review is to summarize potential modulations of the intestinal microbiome aimed at preventing or delaying progression to overt type 1 diabetes in the light of recently identified perturbations of the gut microbiota associated with the development of type 1 diabetes. RECENT FINDINGS: Accumulated data suggest that the gut microbiota is involved at two different steps in the evolution of type 1 diabetes. At the first step, the intestinal tract is colonized by a microbial community unable to provide an adequate education of the immune system...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28942488/psychological-and-biomechanical-aspects-of-patient-adaptation-to-diabetic-neuropathy-and-foot-ulceration
#8
REVIEW
Loretta Vileikyte, Ryan T Crews, Neil D Reeves
PURPOSE OF REVIEW: The purpose of this review was to elucidate how psychological and biomechanical factors interrelate in shaping patients' experience with diabetic symmetric polyneuropathy (DSPN) and its sequela-diabetic foot ulceration (DFU). RECENT FINDINGS: Recent findings emphasize the importance not only of neuropathic pain but also of other DSPN symptoms, such as unsteadiness. We highlight the negative spiral between unsteadiness, falls, and psychological distress...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28942485/crowdsourcing-and-automated-retinal-image-analysis-for-diabetic-retinopathy
#9
REVIEW
Lucy I Mudie, Xueyang Wang, David S Friedman, Christopher J Brady
PURPOSE OF REVIEW: As the number of people with diabetic retinopathy (DR) in the USA is expected to increase threefold by 2050, the need to reduce health care costs associated with screening for this treatable disease is ever present. Crowdsourcing and automated retinal image analysis (ARIA) are two areas where new technology has been applied to reduce costs in screening for DR. This paper reviews the current literature surrounding these new technologies. RECENT FINDINGS: Crowdsourcing has high sensitivity for normal vs abnormal images; however, when multiple categories for severity of DR are added, specificity is reduced...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28940145/pharmacological-properties-of-faster-acting-insulin-aspart
#10
REVIEW
Torben Biester, Olga Kordonouri, Thomas Danne
PURPOSE OF REVIEW: Faster aspart is a new formulation of insulin aspart (IAsp) produced by adding the excipients niacinamide and L-arginine. As this new, "ultra-rapid insulin" is available in the EU-market and Canada, the pharmacokinetic and pharmacodynamics data is summarized. RECENT FINDINGS: Faster aspart shows an earlier onset of appearance of insulin in the bloodstream after subcutaneous administration and an earlier onset of glucose-lowering action and a higher glycemic effect within the first 30 min...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28940103/metabolomics-of-diabetic-retinopathy
#11
REVIEW
Gerald Liew, Zhou Lei, Gavin Tan, Nichole Joachim, I-Van Ho, Tien Y Wong, Paul Mitchell, Bamini Gopinath, Ben Crossett
PURPOSE OF REVIEW: Metabolomics is the study of dysregulated metabolites in biological materials. We reviewed the use of the technique to elucidate the genetic and environmental factors that contribute to the development of diabetic retinopathy. RECENT FINDINGS: With regard to metabolomic studies of diabetic retinopathy, the field remains in its infancy with few studies published to date and little replication of results. Vitreous and serum samples are the main tissues examined, and dysregulation in pathways such as the pentose phosphate pathway, arginine to proline pathway, polyol pathway, and ascorbic acidic pathways have been reported...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28920146/cardiovascular-and-mortality-risks-in-migrant-south-asians-with-type-2-diabetes-are-we-winning-the-battle
#12
REVIEW
Emma Johns, Naveed Sattar
PURPOSE OF REVIEW: We seek to describe the relationship between diabetes mellitus and cardiovascular risk in migrant South Asians compared to native white Europeans, and to determine the temporal change in this relationship over recent years. RECENT FINDINGS: Recent evidence suggests that the excess mortality risk associated with diabetes is lower in the migrant South Asian population compared with white Europeans. By contrast, South Asians continue to demonstrate elevated cardiovascular morbidity compared to white Europeans, although to a lesser extent than was observed in previous decades...
September 18, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28913816/re-visiting-the-endocannabinoid-system-and-its-therapeutic-potential-in-obesity-and-associated-diseases
#13
REVIEW
Joyce M Richey, Orison Woolcott
PURPOSE OF REVIEW: The purpose of the review was to revisit the possibility of the endocannabinoid system being a therapeutic target for the treatment of obesity by focusing on the peripheral roles in regulating appetite and energy metabolism. RECENT FINDINGS: Previous studies with the global cannabinoid receptor blocker rimonabant, which has both central and peripheral properties, showed that this drug has beneficial effects on cardiometabolic function but severe adverse psychiatric side effects...
September 14, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28913745/management-of-type-1-diabetes-in-the-hospital-setting
#14
REVIEW
Carlos E Mendez, Guillermo E Umpierrez
PURPOSE OF REVIEW: The purpose of this article was to review recent guideline recommendations on glycemic target, glucose monitoring, and therapeutic strategies, while providing practical recommendations for the management of medical and surgical patients with type 1 diabetes (T1D) admitted to critical and non-critical care settings. RECENT FINDINGS: Studies evaluating safety and efficacy of insulin pump therapy, continuous glucose monitoring, electronic glucose management systems, and closed loop systems for the inpatient management of hyperglycemia are described...
September 14, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28900818/the-effects-of-chronic-aerobic-exercise-on-cardiovascular-risk-factors-in-persons-with-diabetes-mellitus
#15
REVIEW
Emily M Miele, Samuel A E Headley
PURPOSE OF REVIEW: Aerobic exercise training is a component of diabetes mellitus (DM) care guidelines due to its favorable effects on glycemic control and cardiovascular disease (CVD) risk factors. The purpose of this review is to outline the recent evidence regarding the clinical effects of chronic aerobic exercise on CVD risk factors in persons with DM and to compare the effects of varying intensities and types of exercise. RECENT FINDINGS: Among individuals with DM, all types of aerobic exercise training can impact positively on some traditional and non-traditional risk factors for CVD...
September 12, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28875458/screening-intervals-for-diabetic-retinopathy-and-implications-for-care
#16
REVIEW
Peter H Scanlon
PURPOSE OF REVIEW: The purpose of this study is to review the evidence that lower risk groups who could safely be screened less frequently for sight-threatening diabetic retinopathy (DR) than annually. RECENT FINDINGS: Data have demonstrated that people with no DR in either eye are at a low risk of progression to sight-threatening DR over a 2-year period (event rate 4.8 per 1000 person years), irrespective of whether the screening method is one-field non-mydriatic or two-field mydriatic digital photography...
September 5, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28864875/deciphering-the-pathogenesis-of-human-type-1-diabetes-t1d-by-interrogating-t-cells-from-the-scene-of-the-crime
#17
REVIEW
Sally C Kent, Stuart I Mannering, Aaron W Michels, Jenny Aurielle B Babon
PURPOSE OF REVIEW: Autoimmune-mediated destruction of insulin-producing β-cells within the pancreas results in type 1 diabetes (T1D), which is not yet preventable or curable. Previously, our understanding of the β-cell specific T cell repertoire was based on studies of autoreactive T cell responses in the peripheral blood of patients at risk for, or with, T1D; more recently, investigations have included immunohistochemical analysis of some T cell specificities in the pancreas from organ donors with T1D...
September 2, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28779366/t-cell-populations-and-functions-are-altered-in-human-obesity-and-type-2-diabetes
#18
REVIEW
Sothea Touch, Karine Clément, Sébastien André
PURPOSE OF THE REVIEW: Obesity and type 2 diabetes (T2D) are considered chronic inflammatory diseases. While early publications have reported the implication of innate immune cells such as macrophages to promote systemic inflammation and metabolic dysfunctions, recent publications underline the alterations of the T cell compartment in human obesity and type 2 diabetes. These recent findings are the focus of this review. RECENT FINDINGS: In humans, obesity and T2D induce the expansion of proinflammatory T cells such as CD4 Th1, Th17, and CD8 populations, whereas innate T cells such as MAIT and iNKT cells are decreased...
September 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28779365/progress-in-defining-the-genetic-basis-of-diabetic-complications
#19
REVIEW
Emma Dahlström, Niina Sandholm
PURPOSE OF REVIEW: Diabetic complications affecting the kidneys, retina, nerves, and the cardiovasculature are the major causes of morbidity and mortality in diabetes. This paper aims to review the current understanding of the genetic basis of these complications, based on recent findings especially from genome-wide association studies. RECENT FINDINGS: Variants in or near AFF3, RGMA-MCTP2, SP3-CDCA7, GLRA3, CNKSR3, and UMOD have reached genome-wide significance (p value <5 × 10(-8)) for association with diabetic kidney disease, and recently, GRB2 was reported to be associated at genome-wide significance with diabetic retinopathy...
September 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28770542/process-based-treatment-of-diabetes-in-kaiser-permanente-southern-california-how-to-make-diabetes-care-complete
#20
REVIEW
John P Martin, Natalie Aboubechara
PURPOSE OF REVIEW: The purpose of this review was to provide an overview of the Kaiser Permanente Southern California (KPSC) Complete Care management strategy. RECENT FINDINGS: The KPSC Complete Care program allows members of care management teams to coordinate the administration of care for patients with diabetes. This program encompasses teams of physicians, physician assistants, pharmacists, nurse practitioners, registered nurse (RN) care managers, office-based RNs, health educators, and many others to contribute to the glycemic and overall health outcomes for our patients with diabetes...
September 2017: Current Diabetes Reports
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