journal
MENU ▼
Read by QxMD icon Read
search

Current Diabetes Reports

journal
https://www.readbyqxmd.com/read/30008025/disparities-in-care-delivery-and-outcomes-in-young-adults-with-diabetes
#1
REVIEW
Shivani Agarwal, Marisa Hilliard, Ashley Butler
PURPOSE OF REVIEW: This review summarizes the literature on care and outcome disparities in young adults (YA) with type 1 and type 2 diabetes, and outlines remaining needs and suggestions to reduce disparities and improve care. RECENT FINDINGS: Despite well-documented disparities and data from large national and international diabetes populations, the role that social determinants of health play in disease management is largely unstudied. Further, mechanisms of how these risk factors interact with the unique developmental needs of racial-ethnic minority and economically vulnerable young adults with diabetes remain unknown...
July 14, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/30008022/should-metformin-remain-first-line-medical-therapy-for-patients-with-type-2-diabetes-mellitus-and-atherosclerotic-cardiovascular-disease-an-alternative-approach
#2
REVIEW
Josephine L Harrington, Natalia de Albuquerque Rocha, Kershaw V Patel, Subodh Verma, Darren K McGuire
PURPOSE OF REVIEW: With recent cardiovascular outcome trial (CVOT) results for antihyperglycemic medications, the treatment algorithm for patients with type 2 diabetes (T2DM) and atherosclerotic vascular disease (ASCVD) requires revision. RECENT FINDINGS: All completed CVOTs have demonstrated CV safety of the tested medications, with some trials demonstrating CV efficacy. While metformin remains the first-line recommended medication for T2DM, 18-37% of the patients enrolled in the completed CVOTs were not treated with metformin, providing substantial power to assess CV outcomes independent of metformin...
July 14, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29995252/neighborhood-environments-and-diabetes-risk-and-control
#3
REVIEW
Usama Bilal, Amy H Auchincloss, Ana V Diez-Roux
PURPOSE OF REVIEW: The objective of this review is to highlight the evidence on the association between contextual characteristics of residential environments and type 2 diabetes, to provide an overview of the methodological challenges and to outline potential topics for future research in this field. RECENT FINDINGS: The link between neighborhood socioeconomic status or deprivation and diabetes prevalence, incidence, and control is robust and has been replicated in numerous settings, including in experimental and quasi-experimental studies...
July 11, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29995242/sglt2-inhibitors-and-cardiovascular-outcomes-current-perspectives-and-future-potentials
#4
REVIEW
Xiaoming Jia, Paras B Mehta, Yumei Ye, Mahboob Alam, Yochai Birnbaum, Mandeep Bajaj
PURPOSE OF REVIEW: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have been shown to exert benefit on cardiac outcomes. In this review, we provide updates on available clinical data, studies on potential mechanisms for the CV effects, as well as discuss potential clinical implications of these new findings. RECENT FINDINGS: Since the publications of the EMPA-REG and CANVAS trials, large multi-national cohort studies have further shown the cardioprotective effects of SGLT2i...
July 11, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29995215/emerging-approaches-in-surveillance-of-type-1-diabetes
#5
REVIEW
Sharon Saydah, Giuseppina Imperatore
PURPOSE OF REVIEW: Surveillance of type 1 diabetes provides an opportunity to address public health needs, inform etiological research, and plan health care services. We present issues in type 1 diabetes surveillance, review previous and current methods, and present new initiatives. RECENT FINDINGS: Few diabetes surveillance systems distinguish between type 1 and type 2 diabetes. Most worldwide efforts have focused on registries and ages < 15 years, resulting in limited information among adults...
July 11, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29974263/diabetes-among-non-overweight-individuals-an-emerging-public-health-challenge
#6
REVIEW
Unjali P Gujral, Mary Beth Weber, Lisa R Staimez, K M Venkat Narayan
PURPOSE OF REVIEW: Overweight and obesity are well-established risk factors for type 2 diabetes. However, a substantial number of individuals develop the disease at underweight or normal weight. In this review, we discuss the epidemiology of type 2 diabetes in non-overweight adults; pose questions about etiology, pathophysiology, diagnosis, and prognosis; and examine implications for prevention and treatment. RECENT FINDINGS: In population-based studies, the prevalence of type 2 diabetes ranged from 1...
July 4, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29938349/shared-genetic-contribution-of-type-2-diabetes-and-cardiovascular-disease-implications-for-prognosis-and-treatment
#7
REVIEW
Rona J Strawbridge, Natalie R van Zuydam
PURPOSE OF REVIEW: The increased cardiovascular disease (CVD) risk in subjects with type 2 diabetes (T2D) is well established. This review collates the available evidence and assesses the shared genetic background between T2D and CVD: the causal contribution of common risk factors to T2D and CVD and how genetics can be used to improve drug development and clinical outcomes. RECENT FINDINGS: Large-scale genome-wide association studies (GWAS) of T2D and CVD support a shared genetic background but minimal individual locus overlap...
June 25, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29931562/monogenic-diabetes-in-children-and-adolescents-recognition-and-treatment-options
#8
REVIEW
May Sanyoura, Louis H Philipson, Rochelle Naylor
PURPOSE OF REVIEW: We provide a review of monogenic diabetes in young children and adolescents with a focus on recognition, management, and pharmacological treatment. RECENT FINDINGS: Monogenic forms of diabetes account for approximately 1-2% of diabetes in children and adolescents, and its incidence has increased in recent years due to greater awareness and wider availability of genetic testing. Monogenic diabetes is due to single gene defects that primarily affect beta cell function with more than 30 different genes reported...
June 22, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29931496/review-of-community-engaged-research-in-pediatric-diabetes
#9
REVIEW
Ashley M Butler, Marisa E Hilliard, DeLawnia Comer-HaGans
PURPOSE OF REVIEW: Community-engaged research (CER), which is characterized by collaborations between researchers and community partners, is a promising approach to bridge the gaps in translating research evidence into care settings and to address health disparities. This review describes CER in investigations focused on pediatric diabetes. RECENT FINDINGS: Studies were focused on African American, Hispanic, and Native American youth. Most studies aimed to develop and evaluate preventive interventions for type 2 diabetes...
June 22, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29931398/advances-in-the-genetics-of-youth-onset-type-2-diabetes
#10
REVIEW
Jennifer N Todd, Shylaja Srinivasan, Toni I Pollin
PURPOSE OF REVIEW: To provide an update on knowledge the role of genetics in youth-onset type 2 diabetes (T2D). RECENT FINDINGS: The prevalence in youth of T2D, once thought to be exclusively a disease of adults, has increased by over 35% since 2001. Youth with T2D tend to have higher rates of complications, more aggressive disease, with more rapid loss of beta-cell function and a less favorable response to treatment than adults. Obesity is the most important risk factor for T2D, and the rise in childhood overweight and obesity appears responsible for the dramatic increase in T2D in youth...
June 22, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29931613/the-gut-microbiome-as-a-target-for-the-treatment-of-type-2-diabetes
#11
REVIEW
Ömrüm Aydin, Max Nieuwdorp, Victor Gerdes
PURPOSE OF REVIEW: The objective of this review is to critically assess the contributing role of the gut microbiota in human obesity and type 2 diabetes (T2D). RECENT FINDINGS: Experiments in animal and human studies have produced growing evidence for the causality of the gut microbiome in developing obesity and T2D. The introduction of high-throughput sequencing technologies has provided novel insight into the interpersonal differences in microbiome composition and function...
June 21, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29931579/hypoglycemia-among-patients-with-type-2-diabetes-epidemiology-risk-factors-and-prevention-strategies
#12
REVIEW
Richard Silbert, Alejandro Salcido-Montenegro, Rene Rodriguez-Gutierrez, Abdulrahman Katabi, Rozalina G McCoy
PURPOSE OF REVIEW: Hypoglycemia is the most common and often treatment-limiting serious adverse effect of diabetes therapy. Despite being potentially preventable, hypoglycemia in type 2 diabetes incurs substantial personal and societal burden. We review the epidemiology of hypoglycemia in type 2 diabetes, discuss key risk factors, and introduce potential prevention strategies. RECENT FINDINGS: Reported rates of hypoglycemia in type 2 diabetes vary widely as there is marked heterogeneity in how hypoglycemia is defined, measured, and reported...
June 21, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29931547/strategies-to-prevent-readmission-in-high-risk-patients-with-diabetes-the-importance-of-an-interdisciplinary-approach
#13
REVIEW
Naina Sinha Gregory, Jane J Seley, Savira Kochhar Dargar, Naveen Galla, Linda M Gerber, Jennifer I Lee
PURPOSE OF REVIEW: Patients with diabetes are known to have higher 30-day readmission rates compared to the general inpatient population. A number of strategies have been shown to be effective in lowering readmission rates. RECENT FINDINGS: A review of the current literature revealed several strategies that have been associated with a decreased risk of readmission in high-risk patients with diabetes. These strategies include inpatient diabetes survival skills education and medication reconciliation prior to discharge to send the patient home with the "right" medications...
June 21, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29931457/impact-of-genetic-determinants-of-hba1c-on-type-2-diabetes-risk-and-diagnosis
#14
REVIEW
Chloé Sarnowski, Marie-France Hivert
PURPOSE OF REVIEW: Glycated hemoglobin (A1c) is used to diagnose type 2 diabetes and monitor glycemic control. Specific genetic variants interfere with A1c and effects/frequencies of some variants vary by ancestry. In this review, we summarize findings from large trans-ethnic meta-analyses of genome-wide association studies (GWAS) of A1c and describe some variants influencing erythrocyte biology and interfering with A1c. RECENT FINDINGS: Recent GWAS meta-analyses have revealed 60 loci associated with A1c in multi-ethnic populations...
June 21, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29909550/methods-for-measuring-risk-for-type-2-diabetes-in-youth-the-oral-glucose-tolerance-test-ogtt
#15
REVIEW
Melinda E Chen, Rebecca S Aguirre, Tamara S Hannon
PURPOSE OF REVIEW: The oral glucose tolerance test (OGTT) is used both in clinical practice and research to assess glucose tolerance. In addition, the OGTT is utilized for surrogate measures of insulin sensitivity and the insulin response to enteral glucose and has been widely applied in the evaluation of β-cell dysfunction in obesity, prediabetes, and type 2 diabetes. Here we review the use of the OGTT and the OGTT-derived indices for measurement of risk markers for type 2 diabetes in youth...
June 16, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29909496/transplantation-of-macroencapsulated-insulin-producing-cells
#16
REVIEW
Albert J Hwa, Gordon C Weir
PURPOSE OF REVIEW: There is considerable interest in using macroencapsulation devices as a delivery strategy for transplanting insulin-producing cells. This review aims to summarize recent advances, to highlight remaining challenges, and to provide recommendations for the field. RECENT FINDINGS: A variety of new device designs have been reported to improve biocompatibility and to provide protection for islet/beta cells from immune destruction while allowing continuous secretion of insulin...
June 16, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29907898/inpatient-glycemic-management-of-non-cardiac-cvd-focus-on-stroke-and-pvd
#17
REVIEW
Estelle Everett, Nestoras Mathioudakis
PURPOSE OF REVIEW: Hyperglycemia occurs frequently in hospitalized patients with stroke and peripheral vascular disease (PVD). Guidelines for inpatient glycemic management are not well established for this patient population. We will review the clinical impact of hyperglycemia in this acute setting and review the evidence for glycemic control. RECENT FINDINGS: Hyperglycemia in acute stroke is associated with poor short and long-term outcomes, and perioperative hyperglycemia in those undergoing revascularization for PVD is linked to increased post-surgical complications...
June 16, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29907884/availability-and-affordability-of-essential-medicines-implications-for-global-diabetes-treatment
#18
REVIEW
David Beran, Margaret Ewen, Kasia Lipska, Irl B Hirsch, John S Yudkin
PURPOSE OF REVIEW: The purpose of this review is to highlight the key issues with regard to the value, affordability, and availability of diabetes treatments. RECENT FINDINGS: Many of the medicines needed to manage diabetes are available as generics and, if purchased appropriately, can be made affordable to many individuals and systems. With new treatments for diabetes, additional costs to individuals and systems need to be assessed in terms of added clinical benefit and financial impact...
June 16, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29904886/type-1-diabetes-in-a-resource-poor-setting-malnutrition-related-malnutrition-modified-or-just-diabetes
#19
REVIEW
Shitaye Alemu Balcha, David I W Phillips, Elisabeth R Trimble
PURPOSE OF REVIEW: Very little is known about the occurrence of type 1 diabetes (T1DM) in resource-poor countries and particularly in their rural hinterlands. RECENT FINDINGS: Studies of the epidemiology of T1DM in Ethiopia and similar countries in sub-Saharan Africa show that the pattern of presenting disease differs substantially from that in the West. Typically, the peak age of onset of the disease is more than a decade later with a male excess and a low prevalence of indicators of islet-cell autoimmunity...
June 14, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29896650/congenital-diabetes-comprehensive-genetic-testing-allows-for-improved-diagnosis-and-treatment-of-diabetes-and-other-associated-features
#20
REVIEW
Lisa R Letourneau, Siri Atma W Greeley
PURPOSE OF REVIEW: The goal of this review is to provide updates on congenital (neonatal) diabetes from 2011 to present, with an emphasis on publications from 2015 to present. RECENT FINDINGS: There has been continued worldwide progress in uncovering the genetic causes of diabetes presenting within the first year of life, including the recognition of nine new causes since 2011. Management has continued to be refined based on underlying molecular cause, and longer-term experience has provided better understanding of the effectiveness, safety, and sustainability of treatment...
June 13, 2018: Current Diabetes Reports
journal
journal
39539
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"