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JOP: Journal of the Pancreas

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https://www.readbyqxmd.com/read/29599665/management-of-gastroenteropancreatic-neuroendocrine-tumors-gep-nets-in-2017
#1
COMMENT
Muhammad Wasif Saif
No abstract text is available yet for this article.
November 2017: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/29731700/preventing-post-ercp-pancreatitis-the-role-of-prophylactic-pancreatic-duct-stenting-in-the-rectal-nsaid-era
#2
Noor-L-Houda Bekkali, Tom Thomas, Margaret Geraldine Keane, Sam Murray, Deepak Joshi, Ghassan Elsayed, Gavin James Johnson, Michael Huw Chapman, Stephen Paul Pereira, George John Mitchell Webster
Background: Rectal non-steroidal anti-inflammatory drug at endoscopic retrograde cholangiopancreatography is now the standard of care to reduce the risk of post-ERCP pancreatitis. Pancreatic duct stenting also reduces the risk of post- ERCP pancreatitis in high-risk patients, but failed pancreatic duct stenting carries an increased PEP rate (up to 35%). Study Aim: To assess the impact on post-ERCP pancreatitis of successful and unsuccessful pancreatic duct stent placement in the setting of universal rectal non-steroidal anti-inflammatory drug use...
July 2017: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/28824351/confocal-endomicroscopy-characteristics-of-different-intraductal-papillary-mucinous-neoplasm-subtypes
#3
Amrit K Kamboj, John M Dewitt, Rohan M Modi, Darwin L Conwell, Somashekar G Krishna
Intraductal papillary mucinous neoplasms are classified into gastric, intestinal, pancreatobiliary, and oncocytic subtypes where morphology portends disease prognosis. The study aim was to demonstrate EUS-guided needle-based confocal laser endomicroscopy imaging features of intraductal papillary mucinous neoplasm subtypes. Four subjects, each with a specific intraductal papillary mucinous neoplasm subtype were enrolled. An EUS-guided needle-based confocal laser endomicroscopy miniprobe was utilized for image acquisition...
May 2017: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/28966569/efficacy-of-endotherapy-in-the-treatment-of-pain-associated-with-chronic-pancreatitis-a-systematic-review-and-meta-analysis
#4
Mikram Jafri, Amit Sachdev, Javed Sadiq, David Lee, Ting Taur, Adam Goodman, Frank Gress
BACKGROUND: Endotherapy is a treatment modality that can be used to manage the pain associated with chronic pancreatitis. The aim of this systematic review and meta-analysis is to evaluate the efficacy of endotherapy in the management of pain associated with chronic pancreatitis. METHODS: A search of Medline, Pubmed, and Embase databases between 1988 to December 2014 was conducted to evaluate the use of endotherapy for pain relief in patients with chronic pancreatitis...
March 2017: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/29491829/the-burden-of-systemic-adiposity-on-pancreatic-disease-acute-pancreatitis-non-alcoholic-fatty-pancreas-disease-and-pancreatic-cancer
#5
Ahmad Malli, Feng Li, Darwin L Conwell, Zobeida Cruz-Monserrate, Hisham Hussan, Somashekar G Krishna
Obesity is a global epidemic as recognized by the World Health Organization. Obesity and its related comorbid conditions were recognized to have an important role in a multitude of acute, chronic, and critical illnesses including acute pancreatitis, nonalcoholic fatty pancreas disease, and pancreatic cancer. This review summarizes the impact of adiposity on a spectrum of pancreatic diseases.
2017: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/28912670/the-role-of-real-time-endoscopic-ultrasound-guided-elastography-for-targeting-eus-fna-of-suspicious-pancreatic-masses-a-review-of-the-literature-and-a-single-center-experience
#6
Mikram Jafri, Amit H Sachdev, Lauren Khanna, Frank G Gress
BACKGROUND: Endoscopic ultrasound guided elastography is an imaging modality that can be used to evaluate tissue stiffness and to assess solid pancreatic lesions. It can also assist in optimizing the diagnostic yield of endoscopic ultrasound guided fine needle aspiration biopsies. AIMS: To review the literature on solid pancreatic lesions, the use of EUS guided fine needle aspiration and endoscopic ultrasound guided elastography and to present a single center experience using elastography to direct fine needle aspiration biopsies of solid pancreatic lesions...
September 2016: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/29568247/diabetes-type-2-and-pancreatic-cancer-a-history-unfolding
#7
Andre De Souza, Khawaja Irfan, Faisal Masud, Muhammad Wasif Saif
Pancreatic Cancer is the fourth cause of cancer-related deaths in the United States. Up to 80% of pancreatic cancer patients present with either new-onset type 2 diabetes or impaired glucose tolerance at the time of diagnosis. Recent literature suggests that diabetes mellitus type 2 is a risk factor, a manifestation and a prognostic factor for pancreatic cancer. This article is intended to clarify the evidence about diabetes as a risk factor for pancreatic cancer.
March 2016: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791564/igg4-related-disease
#8
Hisanori Umehara, Mitsuhiro Kawano
No abstract text is available yet for this article.
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791562/acute-pancreatitis-induced-fluid-collections-the-naming-game
#9
Dana M Christopher, Kimberly J Chaput, Kimberly J Fairley, Andrew D Mowery, Christopher Valente, Blake A Stewart, Steven R Bonebrake, Harshit Khara, Amitpal S Johal
No abstract text is available yet for this article.
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791560/undifferentiated-spindle-cell-pancreatic-carcinoma-a-case-report-with-osteochondroid-differentiation
#10
Xing Wang, Yong-Hua Chen, Yun-Qiang Cai, Xu-Bao Liu
CONTEXT: Undifferentiated (spindle cell) carcinomas of the pancreas are rare anaplastic variants of pancreatic ductal adenocarcinoma with a frequency of 2% of pancreatic exocrine tumors. Their clinicopathological features are limited and obtained by few previously case reports. We report a case of undifferentiated pancreatic carcinoma with a rare focal osteochondroid differentiation. CASE REPORT: A sixty-six-year-old woman was admitted to our hospital for abdominal pain and nonspecific nausea for almost 40 days...
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791559/seventy-two-cycles-of-folfirinox-long-term-treatment-in-a-patient-with-metastatic-adenocarcinoma-of-the-pancreatic-tail
#11
Maximilian Tiller, Felix Gundling, Wolfgang Schepp, Martin Fuchs
CONTEXT: Pancreatic adenocarcinoma is one of the most lethal malignancies worldwide. In patients with unresectable tumor there are several strategies of palliative chemotherapy, either gemcitabine based regimens or FOLFIRINOX, which is supposed to be most efficient but also most toxic. Hence, management of toxicity is crucial to perform a therapy consisting of FOLFIRINOX. CASE REPORT: We report on a 69-year-old female patient suffering from adenocarcinoma of the pancreatic tail with multiple liver metastases...
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791558/acute-pancreatitis-secondary-to-diabetic-ketoacidosis-induced-hypertriglyceridemia-in-a-young-adult-with-undiagnosed-type-2-diabetes
#12
Animesh A Singla, Francis Ting, Apresh Singla
CONTEXT: The triad of acute pancreatitis, hypertriglyceridemia and diabetes is a rare occurrence. CASE REPORT: A previously well 19-year-old male presented to the emergency department with 24-hour history of epigastric pain, associated with polyuria and nausea. Biochemical markers showed the presence of hyperglycemia (blood sugar level 15 mmol/L) and ketonemia (5.3 mmol/L). Further investigation revealed severe hypertriglyceridemia (4,009 mg/dL) and elevated lipase (1,714 U/L)...
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791555/acute-pancreatitis-as-initial-presentation-of-cocaine-induced-vasculitis-a-case-report
#13
Ayorinde Ogunbameru, Mohammed Jandali, Amer Issa, Waleed Quwatli, Timothy Woodlock, Wajid Choudhry
CONTEXT: Levamisole-contaminated cocaine is an increasingly reported cause of vasculitis and immunologic abnormalities in cocaine abusers. The systemic effects of vasculitis are commonly seen in the dermatologic, hematologic and renal systems but rarely the gastrointestinal system. CASE REPORT: We present an atypical case of cocaine-induced vasculitis presenting initially as an acute pancreatitis and then rapidly progressing to involve multi-organ systems over the next couple of weeks...
March 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791553/small-bowel-perforation-caused-by-pancreaticojejunal-anastomotic-stent-migration-after-pancreaticoduodenectomy-for-periampullary-carcinoma
#14
Giulio Mari, Andrea Costanzi, Nicola Monzio, Angelo Miranda, Luca Rigamonti, Jacopo Crippa, Paola Sartori, Dario Maggioni
CONTEXT: Pancreaticoduodenectomy is the gold standard for patients with resectable periampullary carcinoma. The protection of the anastomosis by positioning of an intraluminal stent is a technique used to lower the frequency of anastomotic fistulas. However the use of anastomotic stents is still debated and stent related complications are reported. CASE REPORT: A fifty-three-year old male underwent pancreaticoduodenectomy (PD) for a T2N0 periampullary carcinoma with a pancreaticojejunal (duct to mucosa) anastomosis protected by a free floating 6 Fr Nelaton stent in the Wirsung duct...
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791551/does-etiology-of-acute-pancreatitis-matter-a-review-of-391-consecutive-episodes
#15
Gunther Weitz, Julia Woitalla, Peter Wellhöner, Klaus Schmidt, Jürgen Büning, Klaus Fellermann
CONTEXT: Acute pancreatitis can be triggered by a variety of factors ranging from short lasting to sustained disruptions. It is plausible that the characteristics and course of disease differ among etiologies. Data distinguishing characteristics of patients with pancreatitis of biliary, alcoholic, idiopathic or other origin are scarce and conflicting. OBJECTIVE: To compare patients' characteristics, baseline parameters on admission, and outcome in patients with an episode of acute pancreatitis in whom the etiology was thoroughly determined...
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791549/long-term-outcomes-after-acute-necrotizing-pancreatitis-what-happens-to-the-pancreas-and-to-the-patient
#16
Rafaela Cristina Goebel Winter Gasparoto, Marcelo De Castro Jorge Racy, Tercio De Campos
CONTEXT: Late consequences of acute pancreatitis have received little attention. It is controversial whether the pancreas fully recovers after an episode of acute pancreatitis, especially in the presence of necrosis. Therefore, the presence of late pancreatic dysfunction following acute necrotizing pancreatitis is uncertain and there are controversies about how it may affect long-term quality of life. OBJECTIVES: To evaluate pancreatic function and morphology, besides quality of life, in patients with prior acute necrotizing pancreatitis...
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791547/the-role-of-molecular-analysis-in-the-diagnosis-and-surveillance-of-pancreatic-cystic-neoplasms
#17
Megan Winner, Amrita Sethi, John M Poneros, Stavros N Stavropoulos, Peter Francisco, Charles J Lightdale, John D Allendorf, Peter D Stevens, Tamas A Gonda
CONTEXT: Molecular analysis of pancreatic cyst fluid obtained by EUS-FNA may increase diagnostic accuracy. We evaluated the utility of cyst-fluid molecular analysis, including mutational analysis of K-ras, loss of heterozygosity (LOH) at tumor suppressor loci, and DNA content in the diagnoses and surveillance of pancreatic cysts. METHODS: We retrospectively reviewed the Columbia University Pancreas Center database for all patients who underwent EUS/FNA for the evaluation of pancreatic cystic lesions followed by surgical resection or surveillance between 2006-2011...
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791546/crohn-s-disease-and-acute-pancreatitis-a-review-of-literature
#18
Sarfaraz Jasdanwala, Mark Babyatsky
Crohn's disease, a transmural inflammatory bowel disease, has many well-known extra-intestinal manifestations and complications. Although acute pancreatitis has a higher incidence in patients with Crohn's disease as compared to the general population, acute pancreatitis is still relatively uncommon in patients with Crohn's disease. Patients with Crohn's disease are at an approximately fourfold higher risk than the general population to develop acute pancreatitis. The risk of developing acute pancreatitis is higher in females as compared to males...
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791545/necrotizing-pancreatitis-a-review-of-multidisciplinary-management
#19
Anthony Sabo, Naeem Goussous, Neeraj Sardana, Shirali Patel, Steven C Cunningham
The objective of this review is to summarize the current state of the art of the management of necrotizing pancreatitis, and to clarify some confusing points regarding the terminology and diagnosis of necrotizing pancreatitis, as these points are essential for management decisions and communication between providers and within the literature. Acute pancreatitis varies widely in its clinical presentation. Despite the publication of the Atlanta guidelines, misuse of pancreatitis terminology continues in the literature and in clinical practice, especially regarding the local complications associated with severe acute pancreatitis...
March 20, 2015: JOP: Journal of the Pancreas
https://www.readbyqxmd.com/read/25791543/neoadjuvant-therapy-in-pancreatic-cancer-review-article
#20
Moritz Pross, Ulrich F Wellner, Kim C Honselmann, Carlo Jung, Steffen Deichmann, Tobias Keck, Dirk Bausch
CONTEXT: Pancreatic cancer is still associated with a high mortality and morbidity for affected patients. To this date the role of neoadjuvant therapy in the standard treatment of pancreatic cancer remains elusive. The aim of our study was to review the latest results and current approaches in neoadjuvant therapy of pancreatic cancer. METHODS: We performed a literature review for neoadjuvant therapy in pancreatic cancer. We divided the results into resectable disease and local advanced pancreatic cancer...
March 20, 2015: JOP: Journal of the Pancreas
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