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BMC Complementary and Alternative Medicine

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https://www.readbyqxmd.com/read/30227851/paediatric-massage-for-treatment-of-acute-diarrhoea-in-children-a-meta-analysis
#1
Li Gao, Chunhua Jia, Huiwen Huang
BACKGROUND: Massage therapy has been used by many traditional Chinese medicine physicians to treat acute diarrhoea in children. Since no relevant systematic reviews assessed the clinical effectiveness or the risk of massage therapy, in this study, a meta-analysis was conducted to evaluate the efficacy of paediatric massage for the treatment of acute diarrhoea in children. METHODS: In this meta-analysis, paediatric patients who were diagnosed with acute diarrhoea were included...
September 18, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30223827/ameliorative-effect-of-taurine-chloramine-in-azathioprine-induced-testicular-damage-a-deeper-insight-into-the-mechanism-of-protection
#2
Mona F Schaalan, Basma K Ramadan, Azza H Abd Elwahab
BACKGROUND: The male reproductive system is a sensitive and intricate process that can be distressed following exposure to various toxicants. Therapeutic drugs, especially chemotherapeutics, can also adversely affect male fertility by instigating hormonal changes leading to testicular cells injury. Azathioprine (AZA) is an effective anticancer drug, but some cases of testicular toxicity have been reported. The aim of this work was to investigate the protective effects of taurine chloramine (TAU-Cl), a reported antioxidant and antiinflammtory peptide, against AZA-induced testicular dysfunction in male rats and ascertain the contributing mechanisms...
September 17, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30223811/identification-of-antitumoral-agents-against-human-pancreatic-cancer-cells-from-asteraceae-and-lamiaceae-plant-extracts
#3
Lamia Mouhid, Marta Gómez de Cedrón, Teodoro Vargas, Elena García-Carrascosa, Nieves Herranz, Mónica García-Risco, Guillermo Reglero, Tiziana Fornari, Ana Ramírez de Molina
BACKGROUND: Pancreatic cancer is one of the most aggressive and mortal cancers. Although several drugs have been proposed for its treatment, it remains resistant and new alternatives are needed. In this context, plants and their derivatives constitute a relevant source of bioactive components which might efficiently inhibit tumor cell progression. METHODS: In this study, we have analyzed the potential anti-carcinogenic effect of different Asteraceae (Achillea millefolium and Calendula officinalis) and Lamiaceae (Melissa officinalis and Origanum majorana) plant extracts obtained by different green technologies (Supercritical CO2 Extraction -SFE- and Ultrasonic Assisted Extraction -UAE-) to identify efficient plant extracts against human pancreatic cancer cells that could constitute the basis of novel treatment approaches...
September 17, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30223807/yiqihuoxue-decoction-protects-against-post-myocardial-infarction-injury-via-activation-of-cardiomyocytes-pgc-1%C3%AE-expression
#4
Fanghe Li, Shuwen Guo, Chunguo Wang, Xiaolou Huang, Hui Wang, Xiaobo Tan, Qian Cai, Jiani Wu, Yuqin Zhang, Xi Chen, Wangou Lin, Binyue Zhang
BACKGROUND: Mitochondrial dysfunction has been implicated in the pathogenesis of ischemic heart disease, exacerbating cardiomyocytes injury in myocardial infarction (MI). Peroxisome proliferator-activated receptor gamma co-activator (PGC-1α) has been recognized as the key regulator of mitochondrial biogenesis and energy metabolism. Yiqihuoxue decoction (YQHX), a Traditional Chinese Medicine (TCM) prescription, can prevent and treat ischemic heart disease. However, the mechanisms of YQHX on PGC-1α expression in the ischemic heart have remained unclear...
September 17, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30223806/antioxidant-and-skin-whitening-effects-of-aerial-part-of-euphorbia-supina-raf-extract
#5
Sa-Haeng Kang, Yong-Deok Jeon, Ji-Yoon Cha, Sung-Woo Hwang, Hoon-Yeon Lee, Min Park, Bo-Ri Lee, Min-Kyoung Shin, Su-Jeong Kim, Sang-Min Shin, Dae-Ki Kim, Jong-Sik Jin, Young-Mi Lee
BACKGROUND: Euphorbia supina (ES) has been widely used in folk medicine owing to its antibacterial, hemostatic, and anti-inflammatory properties. The aim of this study was to evaluate the antioxidant and skin-whitening effects of a 70% ethanol extract of ES. METHODS: The aerial parts of ES plant were extracted with 70% ethanol. The viability of B16F10 cells was evaluated by MTT assay to determine the non-toxic doses for further experiments. The tyrosinase and cellular tyrosinase activities were then measured using an enzyme-substrate assay...
September 17, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30219066/antimicrobial-activities-of-flavonoid-glycosides-from-graptophyllum-grandulosum-and-their-mechanism-of-antibacterial-action
#6
Cyrille Ngoufack Tagousop, Jean-de-Dieu Tamokou, Steve Endeguele Ekom, David Ngnokam, Laurence Voutquenne-Nazabadioko
BACKGROUND: The search for new antimicrobials should take into account drug resistance phenomenon. Medicinal plants are known as sources of potent antimicrobial compounds including flavonoids. The objective of this investigation was to evaluate the antimicrobial activities of flavonoid glycosides from Graptophyllum grandulosum, as well as to determine their mechanism of antibacterial action using lysis, leakage and osmotic stress assays. METHODS: The plant extracts were prepared by maceration in organic solvents...
September 15, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30208908/assessment-of-acute-14-day-and-13-week-repeated-oral-dose-toxicity-of-tiglium-seed-extract-in-rats
#7
Jun-Won Yun, Euna Kwon, Yun-Soon Kim, Seung-Hyun Kim, Ji-Ran You, Hyoung-Chin Kim, Jin-Sung Park, Jeong-Hwan Che, Sang-Koo Lee, Ja-June Jang, Hyeon Hoe Kim, Byeong-Cheol Kang
BACKGROUND: Seed of mature Croton tiglium Linne, also known as Tiglium seed (TS), has been widely used as a natural product due to its several health beneficial properties including anti-tumor and antifungal activities. Despite its ethnomedicinal beneficial properties, toxicological information regarding TS extract, especially its long-term toxicity, is currently limited. Therefore, the objective of the present study was to evaluate acute and subchronic toxicity of TS extract in rats after oral administration following test guidelines of the Organization for Economic Cooperation and Development (OECD)...
September 12, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30200963/sargassum-horneri-turner-c-agardh-ethanol-extract-inhibits-the-fine-dust-inflammation-response-via-activating-nrf2-ho-1-signaling-in-raw-264-7-cells
#8
Thilina U Jayawardena, K K Asanka Sanjeewa, I P Shanura Fernando, Bo Mi Ryu, Min-Cheol Kang, Youngheun Jee, Won Woo Lee, You-Jin Jeon
BACKGROUND: Among the different kinds of pollution, air pollution continues to increase globally. East Asia is considered to be significantly affected. As a result, the populations in these regions face serious health issues including respiratory disorders. This study investigated the impact of fine dust (FD) particles (CRM No. 28) on macrophage cells as a model for alveolar lung cells. METHODS: The research focused on inflammation and oxidative stress induced by FD and Sargassum horneri (Turner) C...
September 10, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30200948/weipixiao-attenuate-early-angiogenesis-in-rats-with-gastric-precancerous-lesions
#9
Jinhao Zeng, Ran Yan, Huafeng Pan, Fengming You, Tiantian Cai, Wei Liu, Chuan Zheng, Ziming Zhao, Daoyin Gong, Longhui Chen, Yi Zhang
BACKGROUND: Angiogenesis is a pathobiological hallmark of gastric cancer. However, rare studies focus on angiogenesis in gastric precancerous lesions (GPL). Weipixiao (WPX), a Chinese herbal preparation, is proved clinically effective in treating GPL. Here, we evaluated WPX's anti-angiogenic potential for GPL, and also investigated the possibility of its anti-angiogenic mechanisms. METHODS: HPLC analysis was applied to screen the major chemical components of WPX...
September 10, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30189898/epigallocatechin-gallate-inhibits-hepatitis-b-virus-infection-in-human-liver-chimeric-mice
#10
Yu-Heng Lai, Cheng-Pu Sun, Hsiu-Chen Huang, Jui-Chieh Chen, Hui-Kang Liu, Cheng Huang
BACKGROUND: Persistent hepatitis B virus (HBV) infection causes liver cirrhosis and hepatocellular carcinoma and constitutes a major worldwide health problem. Currently, anti-HBV drugs are limited to peginterferon and nucleos(t)ide analogs, which are costly and have considerable side effects; the development of novel, effective anti-HBV agents is crucial. METHODS: Catechins are a major group of compounds found in green tea extract and epigallocatechin gallate (EGCG) has been shown to have antiviral properties, including inhibition of cellular entry by HBV...
September 6, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30189873/efficacy-of-sida-pilosa-retz-aqueous-extract-against-schistosoma-mansoni-induced-granulomatous-inflammation-in-the-liver-and-the-intestine-of-mice-histomorphometry-and-gastrointestinal-motility-evaluation
#11
Hermine Boukeng Jatsa, Ulrich Membe Femoe, Joseph Njiaza, Daniel Simplice Tombe Tombe, Lohik Nguegan Mbolang, Emilienne Tienga Nkondo, Louis-Albert Tchuem Tchuente, Théophile Dimo, Pierre Kamtchouing
BACKGROUND: The macerate of Sida pilosa aerial parts is used empirically for the treatment of intestinal helminthiasis. Previous studies have shown that Sida pilosa aqueous extract (SpAE) has schistosomicidal, antioxidant, anti-inflammatory and anti-fibrotic activities in Schistosoma mansoni infection. This study was designed to evaluate the effect of SpAE on the granulomatous inflammation induced by S. mansoni in the liver and the intestine of mice by histomorphometry; as well as on the gastrointestinal motility...
September 6, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30185182/patterns-of-conventional-and-complementary-non-pharmacological-health-practice-use-by-us-military-veterans-a-cross-sectional-latent-class-analysis
#12
Melvin T Donaldson, Melissa A Polusny, Rich F MacLehose, Elizabeth S Goldsmith, Emily M Hagel Campbell, Lynsey R Miron, Paul D Thuras, Erin E Krebs
BACKGROUND: Non-pharmacological therapies and practices are commonly used for both health maintenance and management of chronic disease. Patterns and reasons for use of health practices may identify clinically meaningful subgroups of users. The objectives of this study were to identify classes of self-reported use of conventional and complementary non-pharmacological health practices using latent class analysis and estimate associations of participant characteristics with class membership...
September 5, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30176904/efficacy-of-andrographis-paniculata-against-extended-spectrum-%C3%AE-lactamase-esbl-producing-e-coli
#13
Ubaid Rasool, Priya S, Afsana Parveen, Saroj Kumar Sah, Hemalatha S
BACKGROUND: A. paniculata is widely known for its medicinal values and is traditionally used to treat a wide range of diseases such as cancer, diabetes, skin infections, influenza, diarrhoea, etc. The phytochemical constituents of this plant possess unique and interesting biological activities. The main focus of this study was to evaluate the antibacterial property of crude ethyl acetate (CEA) extract of A. paniculata against E. coli clinical isolates along with molecular docking of 10 different bioactive components from this plant with CTX-M-15...
September 3, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30176849/the-protective-effect-of-er-xian-decoction-against-myocardial-injury-in-menopausal-rat-model
#14
Zhiguo Zhang, Lihua Xiang, Lanping Zhao, Hong Jiao, Zhen Wang, Yubo Li, Yanjing Chen
BACKGROUND: Er-Xian decoction (EXD), a formula of Chinese medicine, is often used to treat menopausal syndrome in China. The aim of the present study was to explore the potential cardioprotective mechanism of EXD against myocardial injury in an ovariectomy-induced menopausal rat model. METHODS: We divided the female Wistar rats into ovariectomy group and sham operation group (SHAM group). The ovariectomized (OVX) rats received treatment of vehicle (OVX group), EXD (EXD group) or 17β-estradiol (E2 group)...
September 3, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30170584/efficacy-and-safety-of-tripterygium-wilfordii-hook-f-for-chronic-urticaria-a-systematic-review-and-meta-analysis
#15
REVIEW
Liu Liu, Huaibo Zhao, Xiaoying Sun, Qi Zheng, Ying Luo, Yi Ru, Ying Zhang, Xi Chen, Bo Zhu, Chengqian Yin, Bin Li, Xin Li
BACKGROUND: The first-line agents comprising antihistamines for chronic urticaria, are not completely satisfactory. Tripterygium wilfordii Hook F (TwHF), a Chinese herb, has been developed into several Tripterygium agents and have definite effects on autoimmune and inflammatory diseases. In chronic urticaria, however, their values of practical application remain unclear. The aim of this study was to investigate the efficacy and safety of TwHF in patients with chronic urticaria. METHODS: Several databases were systematically searched including PubMed, Embase, Cochrane Central Register of Controlled Trials, China Network Knowledge Infrastructure, Chinese Scientific Journals Database, Wan Fang Database, and Chinese Biomedicine...
August 31, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30165848/comparison-of-the-main-components-and-bioactivity-of-rhus-verniciflua-stokes-extracts-by-different-detoxification-processing-methods
#16
Seon-Ok Lee, Sung-Ji Kim, Ju-Sung Kim, Hyuk Ji, Eun-Ok Lee, Hyo-Jeong Lee
BACKGROUND: Rhus verniciflua Stokes is an Asian tree species that is used as a food supplement and traditional medicine in Korea. However, its use is restricted by its potential to cause allergy. Thus, allergen-free R. verniciflua extracts are currently being marketed as a functional health food in Korea. In the present study, three different allergen-free R. verniciflua extracts (DRVE, FRVE, and FFRVE) were produced by detoxification of R. verniciflua, and their properties and constituents were compared...
August 30, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30157825/complementary-and-alternative-medicine-use-among-children-with-mental-health-issues-results-from-the-national-health-interview-survey
#17
Claudia Wang, John Preisser, Yunro Chung, Kaigang Li
BACKGROUND: Mental health issues in children have become a serious public health concern in the U.S. within the past few decades. Emerging evidence suggests that Complementary and Alternative Medicine (CAM) can be beneficial for various mental health issues. However, little is known about the prevalence, reasons, and associated factors of CAM use among this population in the U.S. The purpose of this study is to examine the characteristics of CAM use among U.S. children with mental health issues...
August 29, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30134897/antioxidant-and-anticancer-activities-of-trigonella-foenum-graecum-cassia-acutifolia-and-rhazya-stricta
#18
Bayan Al-Dabbagh, Ismail A Elhaty, Ala'a Al Hrout, Reem Al Sakkaf, Raafat El-Awady, S Salman Ashraf, Amr Amin
BACKGROUND: Here, we determined in vitro antioxidant activity, total phenols and flavonoids and evaluated antiproliferative activity of three medicinal plant extracts: Trigonella foenum-graecum (Fenugreek), Cassia acutifolia (Senna) and Rhazya stricta (Harmal). METHODS: The leaves of the three medicinal plants were extracted with 70% ethanol. Antioxidant activities of the extracts were determined by using DPPH (1,1-diphenyl-2-picrylhydrazyl) assay. Total flavonoid and phenolic contents were determined using colorimetric assays...
August 22, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30107806/corylin-inhibits-lps-induced-inflammatory-response-and-attenuates-the-activation-of-nlrp3-inflammasome-in-microglia
#19
Ming-Yii Huang, Chia-En Tu, Shu-Chi Wang, Yung-Li Hung, Chia-Cheng Su, Shih-Hua Fang, Chi-Shuo Chen, Po-Len Liu, Wei-Chung Cheng, Yu-Wei Huang, Chia-Yang Li
BACKGROUND: Inflammation has been found to be associated with many neurodegenerative diseases, including Parkinson's and dementia. Attenuation of microglia-induced inflammation is a strategy that impedes the progression of neurodegenerative diseases. METHODS: We used lipopolysaccharide (LPS) to simulate murine microglia cells (BV2 cells) as an experimental model to mimic the inflammatory environment in the brain. In addition, we examined the anti-inflammatory ability of corylin, a main compound isolated from Psoralea corylifolia L...
August 15, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/30103722/an-assessment-of-the-use-of-complementary-and-alternative-medicine-by-korean-people-using-an-adapted-version-of-the-standardized-international-questionnaire-i-cam-qk-a-cross-sectional-study-of-an-internet-survey
#20
Ju Ah Lee, Yui Sasaki, Ichiro Arai, Ho-Yeon Go, Sunju Park, Keiko Yukawa, Yun Kung Nam, Seong-Gyu Ko, Yoshiharu Motoo, Kiichiro Tsutani, Myeong Soo Lee
BACKGROUND: In Korea, there are two types of medical doctors: one practises conventional medicine (hereafter called a physician), and the other practises traditional medicine (hereafter called a Korean medical doctor). This study aimed to compare the provision of complementary and alternative medicine (CAM) by these providers to CAM use per self-judgement in Korea. METHODS: We analysed 1668 Korean people via an internet survey with the Korean adopted version of the I-CAM-Q, namely, the International Questionnaire to measure use of CAM, to understand whether respondents used CAM based either on a prescription or advice from a physician or a Korean medical doctor or on self-judgement...
August 13, 2018: BMC Complementary and Alternative Medicine
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