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Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology

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https://www.readbyqxmd.com/read/28260966/peptide-functionalized-iron-oxide-magnetic-nanoparticle-for-gold-mining
#1
Wei-Zheng Shen, Sibel Cetinel, Kumakshi Sharma, Elham Rafie Borujeny, Carlo Montemagno
Here, we present our work on preparing a novel nanomaterial composed of inorganic binding peptides and magnetic nanoparticles for inorganic mining. Two previously selected and well-characterized gold-binding peptides from cell surface display, AuBP1 and AuBP2, were exploited. This nanomaterial (AuBP-MNP) was designed to fulfill the following two significant functions: the surface conjugated gold-binding peptide will recognize and selectively bind to gold, while the magnetic nano-sized core will respond and migrate according to the applied external magnetic field...
2017: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/28260965/enhancement-of-temozolomide-stability-by-loading-in-chitosan-carboxylated-polylactide-based-nanoparticles
#2
Antonio Di Martino, Pavel Kucharczyk, Zdenka Capakova, Petr Humpolicek, Vladimir Sedlarik
In the presented work, amphiphilic nanoparticles based on chitosan and carboxy-enriched polylactic acid have been prepared to improve the stability of the pro-drug temozolomide in physiological media by encapsulation. The carrier, with a diameter in the range of 150-180 nm, was able to accommodate up to 800 μg of temozolomide per mg of polymer. The obtained formulation showed good stability in physiological condition and preparation media up to 1 month. Temozolomide loaded inside the carrier exhibited greater stability than the free drug, in particular in simulated physiological solution at pH 7...
2017: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/28250714/the-effect-of-core-and-lanthanide-ion-dopants-in-sodium-fluoride-based-nanocrystals-on-phagocytic-activity-of-human-blood-leukocytes
#3
Bartlomiej Sojka, Aurelia Liskova, Miroslava Kuricova, Mateusz Banski, Jan Misiewicz, Maria Dusinska, Mira Horvathova, Silvia Ilavska, Michaela Szabova, Eva Rollerova, Artur Podhorodecki, Jana Tulinska
Sodium fluoride-based β-NaLnF4 nanoparticles (NPs) doped with lanthanide ions are promising materials for application as luminescent markers in bio-imaging. In this work, the effect of NPs doped with yttrium (Y), gadolinium (Gd), europium (Eu), thulium (Tm), ytterbium (Yb) and terbium (Tb) ions on phagocytic activity of monocytes and granulocytes and the respiratory burst was examined. The surface functionalization of <10-nm NPs was performed according to our variation of patent pending ligand exchange method that resulted in meso-2,3-dimercaptosuccinic acid (DMSA) molecules on their surface...
2017: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/28250713/identification-and-visualization-of-the-intellectual-structure-and-the-main-research-lines-in-nanoscience-and-nanotechnology-at-the-worldwide-level
#4
Teresa Muñoz-Écija, Benjamín Vargas-Quesada, Zaida Chinchilla-Rodríguez
The aim of this paper is to make manifest the intellectual and cognitive structure of nanoscience and nanotechnology (NST) by means of visualization techniques. To this end, we used data from the Web of Science (WoS), delimiting the data to the category NST during the period of 2000-2013, retrieving a total of 198,275 documents. Through direct author citation of these works, we identified their origins and the seminal papers, and through word co-occurrence extracted from the titles and abstracts, the main lines of research were identified...
2017: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/28250712/reliable-nanomaterial-classification-of-powders-using-the-volume-specific-surface-area-method
#5
Wendel Wohlleben, Johannes Mielke, Alvise Bianchin, Antoine Ghanem, Harald Freiberger, Hubert Rauscher, Marion Gemeinert, Vasile-Dan Hodoroaba
The volume-specific surface area (VSSA) of a particulate material is one of two apparently very different metrics recommended by the European Commission for a definition of "nanomaterial" for regulatory purposes: specifically, the VSSA metric may classify nanomaterials and non-nanomaterials differently than the median size in number metrics, depending on the chemical composition, size, polydispersity, shape, porosity, and aggregation of the particles in the powder. Here we evaluate the extent of agreement between classification by electron microscopy (EM) and classification by VSSA on a large set of diverse particulate substances that represent all the anticipated challenges except mixtures of different substances...
2017: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/28163602/differential-pattern-of-deposition-of-nanoparticles-in-the-airways-of-exposed-workers
#6
Elizabeth Fireman, Rinat Edelheit, Moshe Stark, Amir Bar Shai
Ultrafine particles (UFP) have been postulated to significantly contribute to the adverse health effects associated with exposure to particulate matter (PM). Due to their extremely small size (aerodynamic diameter <100 nm), UFP are able to deposit deep within the lung after inhalation and evade many mechanisms responsible for the clearance of larger particles. There is a lack of biologically relevant personal exposure metrics for exposure to occupational- and environmental-related micro- and nano-sized PM...
2017: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27594804/taking-stock-of-the-occupational-safety-and-health-challenges-of-nanotechnology-2000-2015
#7
P A Schulte, G Roth, L L Hodson, V Murashov, M D Hoover, R Zumwalde, E D Kuempel, C L Geraci, A B Stefaniak, V Castranova, J Howard
Engineered nanomaterials significantly entered commerce at the beginning of the 21st century. Concerns about serious potential health effects of nanomaterials were widespread. Now, approximately 15 years later, it is worthwhile to take stock of research and efforts to protect nanomaterial workers from potential risks of adverse health effects. This article provides and examines timelines for major functional areas (toxicology, metrology, exposure assessment, engineering controls and personal protective equipment, risk assessment, risk management, medical surveillance, and epidemiology) to identify significant contributions to worker safety and health...
June 2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/28042282/facile-control-of-silica-nanoparticles-using-a-novel-solvent-varying-method-for-the-fabrication-of-artificial-opal-photonic-crystals
#8
Weihong Gao, Muriel Rigout, Huw Owens
In this work, the Stöber process was applied to produce uniform silica nanoparticles (SNPs) in the meso-scale size range. The novel aspect of this work was to control the produced silica particle size by only varying the volume of the solvent ethanol used, whilst fixing the other reaction conditions. Using this one-step Stöber-based solvent varying (SV) method, seven batches of SNPs with target diameters ranging from 70 to 400 nm were repeatedly reproduced, and the size distribution in terms of the polydispersity index (PDI) was well maintained (within 0...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/28003794/synthesis-of-indium-nanoparticles-at-ambient-temperature-simultaneous-phase-transfer-and-ripening
#9
Mohammad Aghazadeh Meshgi, Manfred Kriechbaum, Subhajit Biswas, Justin D Holmes, Christoph Marschner
The synthesis of size-monodispersed indium nanoparticles via an innovative simultaneous phase transfer and ripening method is reported. The formation of nanoparticles occurs in a one-step process instead of well-known two-step phase transfer approaches. The synthesis involves the reduction of InCl3 with LiBH4 at ambient temperature and although the reduction occurs at room temperature, fine indium nanoparticles, with a mean diameter of 6.4 ± 0.4 nm, were obtained directly in non-polar n-dodecane. The direct synthesis of indium nanoparticles in n-dodecane facilitates their fast formation and enhances their size-monodispersity...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27774037/uptake-of-silver-nanoparticles-by-monocytic-thp-1-cells-depends-on-particle-size-and-presence-of-serum-proteins
#10
Katja Kettler, Christina Giannakou, Wim H de Jong, A Jan Hendriks, Petra Krystek
Human health risks by silver nanoparticle (AgNP) exposure are likely to increase due to the increasing number of NP-containing products and demonstrated adverse effects in various cell lines. Unfortunately, results from (toxicity) studies are often based on exposure dose and are often measured only at a fixed time point. NP uptake kinetics and the time-dependent internal cellular concentration are often not considered. Macrophages are the first line of defense against invading foreign agents including NPs. How macrophages deal with the particles is essential for potential toxicity of the NPs...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27774036/effect-of-sonication-on-particle-dispersion-administered-dose-and-metal-release-of-non-functionalized-non-inert-metal-nanoparticles
#11
Sulena Pradhan, Jonas Hedberg, Eva Blomberg, Susanna Wold, Inger Odnevall Wallinder
ABSTRACT: In this study, we elucidate the effect of different sonication techniques to efficiently prepare particle dispersions from selected non-functionalized NPs (Cu, Al, Mn, ZnO), and corresponding consequences on the particle dose, surface charge and release of metals. Probe sonication was shown to be the preferred method for dispersing non-inert, non-functionalized metal NPs (Cu, Mn, Al). However, rapid sedimentation during sonication resulted in differences between the real and the administered doses in the order of 30-80 % when sonicating in 1 and 2...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27766020/determining-the-composition-of-gold-nanoparticles-a-compilation-of-shapes-sizes-and-calculations-using-geometric-considerations
#12
Taizo Mori, Torsten Hegmann
ABSTRACT: Size, shape, overall composition, and surface functionality largely determine the properties and applications of metal nanoparticles. Aside from well-defined metal clusters, their composition is often estimated assuming a quasi-spherical shape of the nanoparticle core. With decreasing diameter of the assumed circumscribed sphere, particularly in the range of only a few nanometers, the estimated nanoparticle composition increasingly deviates from the real composition, leading to significant discrepancies between anticipated and experimentally observed composition, properties, and characteristics...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27656105/graphene-enterprise-mapping-innovation-and-business-development-in-a-strategic-emerging-technology
#13
Philip Shapira, Abdullah Gök, Fatemeh Salehi
This paper explores enterprise development and commercialization in the field of graphene. Firm characteristics and relationships, value chain positioning, and factors associated with product entry are examined for a set of 65 graphene-oriented small and medium-sized enterprises located in 16 different countries. As well as secondary sources and bibliometric methods to profile developments in graphene, we use computerized data mining and analytical techniques, including cluster and regression modeling, to identify patterns from publicly available online information on enterprise web sites...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27642258/a-halogen-free-synthesis-of-gold-nanoparticles-using-gold-iii-oxide
#14
Volodymyr Sashuk, Konrad Rogaczewski
Gold nanoparticles are one of the most used nanomaterials. They are usually synthesized by the reduction of gold(III) chloride. However, the presence of halide ions in the reaction mixture is not always welcome. In some cases, these ions have detrimental influence on the morphology and structure of resulting nanoparticles. Here, we present a simple and halogen-free procedure to prepare gold nanoparticles by reduction of gold(III) oxide in neat oleylamine. The method provides the particles with an average size below 10 nm and dispersity of tens of percent...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27642257/new-rapid-method-to-measure-dissolved-silver-concentration-in-silver-nanoparticle-suspensions-by-aggregation-combined-with-centrifugation
#15
Feng Dong, Eugenia Valsami-Jones, Jan-Ulrich Kreft
It is unclear whether the antimicrobial activities of silver nanoparticles (AgNPs) are exclusively mediated by the release of silver ions (Ag(+)) or, instead, are due to combined nanoparticle and silver ion effects. Therefore, it is essential to quantify dissolved Ag in nanosilver suspensions for investigations of nanoparticle toxicity. We developed a method to measure dissolved Ag in Ag(+)/AgNPs mixtures by combining aggregation of AgNPs with centrifugation. We also describe the reproducible synthesis of stable, uncoated AgNPs...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27642256/optimization-of-a-transferred-arc-reactor-for-metal-nanoparticle-synthesis
#16
Matthias Stein, Frank Einar Kruis
The demand for metal nanoparticles is increasing strongly. Transferred arc synthesis is a promising process in this respect, as it shows high production rates, good quality particles and the ability of up-scaling. The influence of several process parameters on the performance of the process in terms of production rate and particle size is investigated. These parameters are the electrode design and adjustment, the gas flow rate and power input. A novel feeding mechanism allows process operation over an extended time period...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27642255/advantages-and-limitations-of-classic-and-3d-qsar-approaches-in-nano-qsar-studies-based-on-biological-activity-of-fullerene-derivatives
#17
Karolina Jagiello, Monika Grzonkowska, Marta Swirog, Lucky Ahmed, Bakhtiyor Rasulev, Aggelos Avramopoulos, Manthos G Papadopoulos, Jerzy Leszczynski, Tomasz Puzyn
In this contribution, the advantages and limitations of two computational techniques that can be used for the investigation of nanoparticles activity and toxicity: classic nano-QSAR (Quantitative Structure-Activity Relationships employed for nanomaterials) and 3D nano-QSAR (three-dimensional Quantitative Structure-Activity Relationships, such us Comparative Molecular Field Analysis, CoMFA/Comparative Molecular Similarity Indices Analysis, CoMSIA analysis employed for nanomaterials) have been briefly summarized...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27616935/comments-on-the-article-by-a-j-lecloux-j-nanopart-res-2015-17-447-regarding-the-use-of-volume-specific-surface-area-vssa-to-classify-nanomaterials
#18
Neil Gibson, Hubert Rauscher, Gert Roebben
In November 2015, an article by A. J. Lecloux was published in this journal (J Nanopart Res, 17:447, 2015). The article focused on the use of volume-specific surface area (VSSA) for the implementation of the European Commission's recommended definition of "nanomaterial". In that paper, VSSA values were calculated for polydisperse particulate materials using a particle number-based averaging method which do not agree with earlier results of VSSA simulations of polydisperse materials reported in 2014 by the Joint Research Centre (JRC) of the European Commission (EC)...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27478406/contact-mechanics-of-highly-porous-oxide-nanoparticle-agglomerates
#19
Andrea Fabre, Samir Salameh, Lucio Colombi Ciacchi, Michiel T Kreutzer, J Ruud van Ommen
Efficient nanopowder processing requires knowledge of the powder's mechanical properties. Due to the large surface area to volume ratio, nanoparticles experience relatively strong attractive interactions, leading to the formation of micron-size porous structures called agglomerates. Significant effort has been directed towards the development of models and experimental procedures to estimate the elasticity of porous objects such as nanoparticle agglomerates; however, none of the existing models has been validated for solid fractions below 0...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/27471426/can-control-banding-be-useful-for-the-safe-handling-of-nanomaterials-a-systematic-review
#20
Adrienne Eastlake, Ralph Zumwalde, Charles Geraci
OBJECTIVES: Control banding (CB) is a risk management strategy that has been used to identify and recommend exposure control measures to potentially hazardous substances for which toxicological information is limited. The application of CB and level of expertise required for implementation and management can differ depending on knowledge of the hazard potential, the likelihood of exposure, and the ability to verify the effectiveness of exposure control measures. A number of different strategies have been proposed for using CB in workplaces where exposure to engineered nanomaterials (ENMs) can occur...
2016: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
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