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Journal of Musculoskeletal & Neuronal Interactions

I D Papanastassiou, M A Gerochristou, C P Zafeiris, I Patoulias, D Ntallas, D Isaakidis, G Papageorgiou
No abstract text is available yet for this article.
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
R Schleip, W Klingler, S Wearing, I Naylor, M Zuegel, K Hoppe
INTRODUCTION: While two laboratory techniques are commonly used to assess the tensile properties of muscle tissue, emerging evidence suggests that the fascial components of these tissues also serve an active role in force generation. Hence, we investigated whether these techniques are sensitive for assessment of fascial micromechanics. METHODS: Force measurements on dissected fascial tissue were performed either using the classical immersion organ bath or using an improved superfusion approach simulating pulsed pharmacological triggers...
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
D Manousaki, F Rauch, G Chabot, J Dubois, M Fiscaletti, N Alos
OBJECTIVES: Knowledge of physiological variations of bone mineral density (BMD) in newborns and infants is necessary to evaluate pathological changes associated with fractures. Limited reference data for children under 5 years old are available. This study provides normative data of lumbar BMD for the Lunar Prodigy in young children under 5 years old. SUBJECTS AND METHODS: We assessed cross-sectionally 155 healthy children (77 boys, 80% Caucasian), ranging in age from newborn to the age of 5 years...
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
A G Culvenor, H Boeth, G Diederichs, W Wirth, G Duda, F Eckstein
OBJECTIVES: To explore changes in bone, muscle and adipose tissue composition in athletes with high physical activity levels at different stages of life. METHODS: Thigh MRIs were acquired at baseline and 2-year follow-up for 20 young (16±1 years) and 20 mature (46±5 years) athletes (10 males, 10 females, respectively). Longitudinal changes in cross-sectional areas (CSAs) of femoral bone, quadriceps muscle, and thigh subcutaneous (SCF) and intermuscular (IMF) adipose tissue were evaluated...
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
M P Yavropoulou, J G Yovos
The skeleton has the ability to perfectly adapt to external forces of the operating environment, by altering its morphology and metabolism in order to meet different needs. This unique adaptive capacity of the skeleton creates an interesting range of biological questions concerning the perception of mechanical or other kinds of signals, the type of receptor, and the molecular pathways involved in this adaptation. Studies of the characteristics of the cellular engineering provide a host of new information that confers to osteocytes the role of the protagonist in the perception and regulation of mechanical effects on the skeleton...
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
A Benoit, T Mustafy, I Londono, G Grimard, C-E Aubin, I Villemure
Fusionless devices are currently designed to treat spinal deformities such as scoliosis by the application of a controlled mechanical loading. Growth modulation by dynamic compression was shown to preserve soft tissues. The objective of this in vivo study was to characterize the effect of static vs. dynamic loading on the bone formed during growth modulation. Controlled compression was applied during 15 days on the 7(th) caudal vertebra (Cd7) of rats during growth spurt. The load was sustained in the "static" group and sinusoidally oscillating in the "dynamic" group...
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
M T García-Gutiérrez, T J Hazell, P J Marín
OBJECTIVES: To evaluate the effects of whole-body vibration (WBV) on skeletal muscle activity and power performance of the upper body during decline bench press exercise at different loads. METHODS: Forty-seven healthy young and active male students volunteered. Each performed dynamic decline bench press repetitions with and without WBV (50 Hz, 2.2 mm) applied through a hamstring bridge exercise at three different loads of their 1-repetition maximum (1RM): 30%, 50%, and 70% 1RM...
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
C F Dionello, D Sá-Caputo, H Vfs Pereira, C R Sousa-Gonçalves, A I Maiworm, D S Morel, E Moreira-Marconi, L L Paineiras-Domingos, D Bemben, M Bernardo-Filho
OBJECTIVES: The aim of this study was to review the literature about the effect of whole body vibration exercise in the BMD in patients with postmenopausal osteoporosis without medications. METHODS: A systematic review was performed. RESULTS: The frequency of the mechanical vibration used in the protocols has varied from 12 to 90 Hz. The time used in the protocols varied from 2 up to 22 months. Techniques with X-rays were used in nine of the twelve publications analyzed, the Dual energy X-ray absorptiometry (DEXA) in eight studies and the High resolution peripheral quantitative computed tomography (HR-pQCT) in one publication...
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
C Stark, P Herkenrath, H Hollmann, S Waltz, I Becker, L Hoebing, O Semler, H Hoyer-Kuhn, I Duran, B Hero, M Hadders-Algra, E Schoenau
OBJECTIVES: to investigate feasibility, safety and efficacy of home-based side-alternating whole body vibration (sWBV) to improve motor function in toddlers with cerebral palsy (CP). METHODS: Randomized controlled trial including 24 toddlers with CP (mean age 19 months (SD±3.1); 13 boys). INTERVENTION: 14 weeks sWBV with ten 9-minute sessions weekly (non-individualized). Group A started with sWBV, followed by 14 weeks without; in group B this order was reversed...
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
S Judex, W Zhang, L R Donahue, E Ozcivici
Little is known about interactions between muscle and bone during the removal and application of mechanical signals. Here, we applied 3wk of hindlimb unloading followed by 3wk of reambulation to a genetically heterogeneous population of 352 adult mice and tested the hypothesis that changes in muscle are associated with changes in bone at the level of the tissue and the genome. During unloading and relative to normally ambulating control mice, most mice lost muscle and cortical bone with large variability across the population...
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
G Clément, W H Paloski, J Rittweger, D Linnarsson, M P Bareille, E Mulder, F L Wuyts, J Zange
OBJECTIVES: We review the studies that have evaluated intermittent short-radius centrifugation as a potential countermeasure for cardiovascular, musculoskeletal, and sensorimotor deconditioning in simulated weightlessness. METHODS: The findings from 18 experimental protocols that have used bed rest and dry immersion for comparing the protective effects of centrifugation versus standing upright or walking, and the effects of continuous vs. periodic exposure to centrifugation are discussed...
June 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
Z Wu, H Wu, H Wang, C Wu, W Xu, L Zhang, H Fan, J Cai, J Ma
No abstract text is available yet for this article.
June 1, 2016: Journal of Musculoskeletal & Neuronal Interactions
Y M Papamerkouriou, A Doulgeraki, Y Gyftodimou, H Athanasopoulou, E Tsiridis, J Anastasopoulos
No abstract text is available yet for this article.
June 1, 2016: Journal of Musculoskeletal & Neuronal Interactions
T Okiura, Y Oishi, A Takemura, A Ishihara
OBJECTIVES: Effects of collagen hydrolysate (CHD) on the oxidative capacity of the tibialis anterior muscle and the cortical and trabecular density of the femur were investigated in senescence-accelerated mouse prone 6 (SAMP6). METHODS: Sixteen-week-old male SAMP6 mice were divided into control (CON) and CHD groups. The CON group was given normal water, while the CHD group was given water containing CHD. Fibre cross-sectional areas (CSAs), fibre succinate dehydrogenase (SDH) staining intensity, and SDH activity of the tibialis anterior muscle were determined at 42 and 60 weeks of age...
June 1, 2016: Journal of Musculoskeletal & Neuronal Interactions
M Tanaka, K Tanaka, J Tategaki, H Fujino
OBJECTIVES: The present study sought to evaluate the effect of electrical stimulation (ES) by using kilohertz frequency on muscle atrophy induced by sepsis. METHODS: Seventeen male ICR mice were randomly divided into 3 groups: control, lipopolysaccharide (LPS)-injected for 4 days, LPS plus ES (LPS+ES). Sepsis was induced by 4 days of an intraperitoneal LPS injection (10 μg/g body weight/day). LPS+ES animals received the LPS injections and ES twice a day for 4 days...
June 1, 2016: Journal of Musculoskeletal & Neuronal Interactions
K Kanaya, K Iba, T Dohke, S Okazaki, T Yamashita
OBJECTIVES: Nociceptors are expressed at peripheral terminals of neurons. Recent studies have shown that TRPV1, a nociceptor, is expressed in bone tissue and regulates bone metabolism. We have demonstrated that a TRPV1 antagonist improved pain-like behavior in ovariectomized (OVX) mice. The aim of this study was to determine whether nociceptors, including TRPV1, acid-sensing ion channel (ASIC) and P2X2/3 are expressed in bone cells, and to examine the effects of nociceptor antagonists on bone metabolism...
June 1, 2016: Journal of Musculoskeletal & Neuronal Interactions
N Dm Jenkins, T J Housh, S L Buckner, H C Bergstrom, C M Smith, K C Cochrane, E C Hill, A A Miramonti, R J Schmidt, G O Johnson, J T Cramer
The purpose of this study was to investigate the effects of 4-weeks of high- versus low-load resistance training to failure on rate of torque development (RTD), electromechanical delay (EMD), and contractile twitch characteristics. Fifteen men (mean±SD; age=21.7±2.4 yrs) were randomly assigned to either a high- (80% 1RM; n=7) or low-load (30% 1RM; n=8) training group and completed elbow flexion resistance training to failure 3 times per week for 4 weeks. The participants were tested at baseline, 2-, and 4-weeks of training...
June 1, 2016: Journal of Musculoskeletal & Neuronal Interactions
B J Hurtgen, C L Ward, K Garg, B E Pollot, S M Goldman, T O McKinley, J C Wenke, B T Corona
OBJECTIVES: Complicated fracture healing is often associated with the severity of surrounding muscle tissue trauma. Since inflammation is a primary determinant of musculoskeletal health and regeneration, it is plausible that delayed healing and non-unions are partly caused by compounding local inflammation in response to concomitant muscle trauma. METHODS AND RESULTS: To investigate this possibility, a Lewis rat open fracture model [tibia osteotomy with adjacent tibialis anterior (TA) muscle volumetric muscle loss (VML) injury] was interrogated...
June 1, 2016: Journal of Musculoskeletal & Neuronal Interactions
K D Stathopoulos, A B Zoubos, N A Papaioannou, D Mastrokalos, A Galanos, P J Papagelopoulos, G Skarantavos
Menopause constitutes a significant cause of bone loss, and it is currently debated whether bone mass is preserved or begins to decline substantially before that time in women. We used pQCT of the tibia to estimate differences of bone mineral mass, bone geometry and derived strength between premenopausal and postmenopausal Caucasian women of different age-groups per decade of age (20-79y). For each individual, we assessed total, trabecular and cortical bone mineral content (BMC, mg) and volumetric bone mineral density (BMD, mg/cm3); total and cortical cross-sectional areas (CSA, mm2); periosteal circumference (PERI_C, mm); endosteal circumference (ENDO_C, mm); mean cortical thickness (CRT_THK, mm); and Stress-Strain Index (SSI) ...
June 1, 2016: Journal of Musculoskeletal & Neuronal Interactions
A J Bayliss, A M Weatherholt, T T Crandall, D L Farmer, J C McConnell, K M Crossley, S J Warden
PURPOSE: The Achilles tendon (AT) must adapt to meet changes in demands. This study explored AT adaptation by comparing properties within the jump and non-jump legs of jumping athletes. Non-jumping control athletes were included to control limb dominance effects. METHODS: AT properties were assessed in the preferred (jump) and non-preferred (lead) jumping legs of male collegiate-level long and/or high jump (jumpers; n=10) and cross-country (controls; n=10) athletes...
June 1, 2016: Journal of Musculoskeletal & Neuronal Interactions
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