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Journal of Musculoskeletal & Neuronal Interactions

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https://www.readbyqxmd.com/read/28250250/establishment-of-heterotopic-ossification-via-sharp-instrument-injury-in-rats
#1
J-C Xu, G-H Wu, L-L Zhou, X-J Yang, J-T Liu
OBJECTIVE: To establish an animal model for heterotopic ossification (HO) induced by sharp instrument injury in Sprague-Dawley (SD) rat and to investigate its possible mechanism. MATERIALS AND METHODS: A total of 48 male SD rats were divided into 3 groups (n=16). In sham group, incision and suture were performed only in the left leg. Partial tenotomy was performed in the left Achilles tendons in the PAT group. In Achilles' tenotomy (AT) group, tenotomy was performed in the left Achilles tendons to establish animal model of EO...
March 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/28250249/one-stage-extreme-lateral-interbody-fusion-and-percutaneous-pedicle-screw-fixation-in-lumbar-spine-tuberculosis
#2
Q-Y Wang, M-G Huang, D-Q Ou, Y-C Xu, J-W Dong, H-D Yin, W Chen, L-M Rong
OBJECTIVES: We explored the efficacy of minimal invasive surgery including one-stage debridement and intervertebral fusion through extreme lateral channel (XLIF) combined with lateral or percutaneous posterior pedicle screw fixation for the treatment of lumbar spine tuberculosis. METHODS: Twenty two patients with lumbar tuberculosis who underwent surgery with XLIF technique and internal fixation were included in the study. Their data about operative time, intraoperative blood loss, bone fusion, kyphosis correction, and clinical recovery were retrospectively collected and analyzed...
March 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/28250248/comparative-effects-of-denosumab-or-bisphosphonate-treatment-on-bone-mineral-density-and-calcium-metabolism-in-postmenopausal-women
#3
A Augoulea, E Tsakonas, I Triantafyllopoulos, D Rizos, E Armeni, N Tsoltos, S Tournis, E Deligeoroglou, A Antoniou, I Lambrinoudaki
OBJECTIVES: To clarify potential differences between denosumab (DNS) and bisphosphonates (BIS) in terms of bone density and bone metabolism, in a sample of postmenopausal women. METHODS: A total of 113 postmenopausal women aged 53-66 years were treated with either DNS or BIS for 12 months. Bone densitometry and laboratory tests were compared between baseline and follow-up. RESULTS: Femoral neck BMD increased in both treatment-arms (FN-BMD, DNS: 0...
March 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/28250247/long-term-wheel-running-can-prevent-deterioration-of-bone-properties-in-diabetes-mellitus-model-rats
#4
A Minematsu, T Hanaoka, D Takeshita, Y Takada, S Okuda, H Imagita, S Sakata
OBJECTIVES: The purpose of this study was to examine the effects of long-term wheel-running on tibia bone properties in T2DM Otsuka Long-Evans Tokushima Fatty (OLETF) rats. METHODS: Ten five-week-old male OLETF rats were used as experimental animals and 5 Long-Evans Tokushima Otsuka (LETO) rats as controls. Half of OLETF rats performed daily voluntary wheel-running for 17 months (OLETF-EXE), while neither the remainder of OLETF nor LETO rats had exercise. At the end of experiment, in addition to serum biochemical and bone formation/resorption marker analyses, bone mass, trabecular bone microarchitecture and cortical bone geometry were analyzed in left tibia, and bone mechanical strength of right tibia was measured...
March 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/28250246/age-related-normative-values-for-handgrip-strength-and-grip-strength-s-usefulness-as-a-predictor-of-mortality-and-both-cognitive-and-physical-decline-in-older-adults-in-northwest-russia
#5
A Turusheva, E Frolova, J-M Degryse
OBJECTIVES: This paper sought to provide normative values for grip strength among older adults across different age groups in northwest Russia and to investigate their predictive value for adverse events. METHODS: A population-based prospective cohort study of 611 community-dwelling individuals 65+. Grip strength was measured using the standard protocol applied in the Groningen Elderly Tests. The cut-off thresholds for grip strength were defined separately for men and women of different ages using a weighted polynomial regression...
March 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/28250245/sex-differences-in-kinetic-and-neuromuscular-control-during-jumping-and-landing
#6
G Márquez, L M Alegre, D Jaén, L Martin-Casado, X Aguado
In the present study, we analysed the kinetic profile together with the lower limb EMG activation pattern during a countermovement jump and its respective landing phase in males and females. Twenty subjects (10 males and 10 females) took part in the study. One experimental session was conducted in order to record kinetic and electromyographic (EMG) parameters during a countermovement jump (CMJ) and the subsequent landing phase. During the CMJ, males recorded a higher (p<0.001) performance than females in terms of jump height and power production...
March 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/28250244/markers-of-bone-metabolism-during-14-days-of-bed-rest-in-young-and-older-men
#7
J Buehlmeier, P Frings-Meuthen, N Mohorko, P Lau, S Mazzucco, J L Ferretti, G Biolo, R Pisot, B Simunic, J Rittweger
OBJECTIVE: We aimed at comparing markers of bone metabolism during unloading in young and older men, and to assess countermeasure effectiveness. METHODS: 16 older (60±2 years) and 8 younger men (23±3 years) underwent bed rest (BR) for 14 days. A subgroup of the Older performed cognitive training during BR and supplemented protein and potassium bicarbonate afterwards. Biochemical markers of bone and calcium/phosphate metabolism were assessed. RESULTS: At baseline urinary NTX and CTX were greater in younger than in older subjects (P<0...
March 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/28250243/changes-in-body-composition-and-bone-of-female-collegiate-soccer-players-through-the-competitive-season-and-off-season
#8
M M Minett, T B Binkley, L A Weidauer, B L Specker
OBJECTIVES: To assess body composition and bone changes pre- to post-season (pre-post) and post- to off-season (post-off) in female soccer athletes (SC). METHODS: Outcomes were assessed using DXA and pQCT in 23 SC and 17 controls at three times throughout season. RESULTS: SC, non-starters in particular, lost lean mass pre-post (-0.9±0.2 kg, p<0.01; not different from controls, p=0.2) and gained fat mass post-off (1.4±0.3 kg, p<0.01; differed from controls, p=0...
March 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973390/effects-of-oncostatin-m-on-cell-proliferation-and-osteogenic-differentiation-in-c3h10t1-2
#9
F Zou, J-C Xu, G-H Wu, L-L Zhou, Q-D Wa, J-Q Peng, X-N Zou
OBJECTIVE: To explore the effects of protein factor Oncostatin M (OSM), a member of the Interleukin-6 (IL-6) family on cell proliferation, osteogenic differentiation and mineralization. MATERIALS AND METHODS: Basal nutrient solutions of different concentrations of OSM (0, 5, 10, 20, 40, 80 ng/ml) were used. In order to divide embryonic origin between mesenchymal stem cells C3H10T1/2 of in vitro cultured mice, and the effects of in vitro proliferation efficiencies of C3H10T1/2 cells of different concentrations of OSM, the C3H10T1/2 cells were divided into four groups: (1) Basal nutrient solution group (negative control); (2) Osteogenesis induced liquid group (positive control); (3) OSM (20 ng/ml) group; (4) Experimental group (osteogenesis induced liquid + OSM (20 ng/ml))...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973389/sodium-selenate-treatment-mitigates-reduction-of-bone-volume-following-traumatic-brain-injury-in-rats
#10
R D Brady, B L Grills, T Romano, J D Wark, T J O'Brien, S R Shultz, S J McDonald
OBJECTIVES: Administration of sodium selenate to rats given traumatic brain injury (TBI) attenuates brain damage and improves long-term behavioural outcomes. We have previously provided evidence that TBI causes bone loss in rats, however the effect of sodium selenate treatment on bone quantity following TBI is unknown. METHODS: Rats were randomly assigned into sham injury or fluid percussion injury (FPI) groups and administered saline or sodium selenate for 12 weeks post-injury...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973388/alterations-in-gene-expression-precede-sarcopenia-and-osteopenia-in-botulinum-toxin-immobilized-mice
#11
J B Vegger, A Brüel, A F Dahlgaard, J S Thomsen
OBJECTIVES: To investigate alteration of bone and muscle gene expression at different time points during 3 weeks of botulinum toxin (BTX) induced immobilization and how this correlate with conventional analysis of bone and muscle. METHODS: Thirty-five 16-week-old female C57BL/6-mice were investigated; 15 were injected with BTX, 15 served as age-matched controls, and 5 as baseline. 5 BTX-injected and 5 control mice were euthanized after 1, 2, and 3 weeks. Analysis included RT-qPCR, dynamic bone histomorphometry, DEXA, µCT, mechanical testing, and muscle cell cross-sectional-area (CSA)...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973387/functional-status-of-the-articularis-genus-muscle-in-individuals-with-knee-osteoarthritis
#12
A Saito, K Okada, I Saito, K Kinoshita, A Seto, Y Takahashi, K Shibata, H Sato, M Wakasa
OBJECTIVES: To clarify the functional status of the articularis genus muscle (AGM) in individuals with knee osteoarthritis (OA) and to analyze the muscle's relationship with knee OA. METHODS: Fifty-two individuals with knee OA (mean age, 73.4 years), 50 elderly individuals without knee OA changes (mean age, 71.2 years) and 75 young individuals (mean age, 20.2 years) were observed the AGM using ultrasonography. The thickness of the AGM, the anteroposterior distance of the suprapatellar bursa, and moving distance of the muscle insertion were measured both at rest and during isometric contraction, and values during contraction were expressed as percentages of the values at rest (%Muscle-Increase, %Bursa-Increase)...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973386/bone-health-measured-using-quantitative-ultrasonography-in-adult-males-with-muscular-dystrophy
#13
C I Morse, J Smith, A Denny, J Tweedale, N D Searle, K Winwood, G L Onambele-Pearson
OBJECTIVES: To compare muscle and bone health markers in adult males (aged 20-59 yrs) with and without muscular dystrophy (MD). METHODS: Participants included 11 Fascioscapulohumeral (FSH), 11 Becker's (Be), 9 limb girdle (LG), 11 Duchenne (DMD), and 14 non-dystrophic controls (CTRL). Physical activity was assessed using Bone (BPAQ) and disability specific (PASIPD) questionnaires. Bone QUS provided T- and Z scores from the Distal Radius (DR) and Mid-shaft tibia (MST)...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973385/acute-corticospinal-and-spinal-modulation-after-whole-body-vibration
#14
A Krause, A Gollhofer, K Freyler, L Jablonka, R Ritzmann
OBJECTIVES: The objective of this study was to investigate neural effects of acute whole body vibration (WBV) on lower limb muscles regarding corticospinal and spinal excitability. METHODS: In 44 healthy subjects (16 f/ 28 m), motor evoked potentials (MEP) and H-reflexes in m. soleus (SOL) and gastrocnemius medialis (GM) were elicited before (t1), immediately after (t2), 2 (t3), 4 (t4) and 10 min after (t5) WBV. RESULTS: After WBV, MEP amplitudes were significantly increased in SOL (t2+15±30%, t3+22±32%, t4+15±35%, t5+20±30%, P<0...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973384/effects-of-fatiguing-constant-versus-alternating-intensity-intermittent-isometric-muscle-actions-on-maximal-torque-and-neuromuscular-responses
#15
C M Smith, T J Housh, E C Hill, K C Cochrane, N Dm Jenkins, R J Schmidt, G O Johnson
OBJECTIVE: To determine the effects of constant versus alternating applications of torque during fatiguing, intermittent isometric muscle actions of the leg extensors on maximal voluntary isometric contraction (MVIC) torque and neuromuscular responses. METHODS: Sixteen subjects performed two protocols, each consisting of 50 intermittent isometric muscle actions of the leg extensors with equal average load at a constant 60% MVIC or alternating 40 then 80% (40/80%) MVIC with a work-to-rest ratio of 6-s on and 2-s off...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973383/effect-of-sex-on-torque-recovery-emg-and-mmg-responses-to-fatigue
#16
E C Hill, T J Housh, C M Smith, K C Cochrane, N Dm Jenkins, J T Cramer, R J Schmidt, G O Johnson
OBJECTIVE: The purpose of the present investigation was to examine the effect of sex on maximal voluntary isometric contraction (MVIC) torque and the EMG and MMG responses as a result of fatiguing, intermittent, submaximal (65% of MVIC), isometric elbow flexion muscle contractions. METHODS: Eighteen men and women performed MVIC trials before (pretest), after (posttest), and 5-min after (5-min recovery) performing 50 intermittent, submaximal isometric muscle contractions...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973382/lower-insulin-sensitivity-is-related-to-lower-relative-muscle-cross-sectional-area-lower-muscle-density-and-lower-handgrip-force-in-young-and-middle-aged-non-diabetic-men
#17
T Gysel, C Tonoli, S Pardaens, D Cambier, J-M Kaufman, H-G Zmierczak, S Goemaere, B Lapauw, P Calders
OBJECTIVES: This study investigated whether an association between insulin resistance (IR) and muscle parameters is appreciable in young healthy men, independent of obesity. Furthermore, markers of muscle metabolism and hormones/possible determinants, were explored. METHODS: 358 healthy young men were divided into a less and more insulin sensitive (LIS [age=33.2±5.4, BMI=23.4±2.3] and MIS [age=35.5±5.3, BMI=28.1±3.7]) group based on upper and lower quartile of HOMA-IR...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973381/forearm-muscle-quality-as-a-better-indicator-of-physical-performance-than-handgrip-strength-in-older-male-ground-golf-players-aged-70-to-89
#18
T Abe, R S Thiebaud, J P Loenneke
OBJECTIVES: To examine the associations between absolute and relative handgrip strength (HGS) and physical performance. METHODS: A total of 135 old men aged 70-89 years had muscle thickness (MT) measured by ultrasound at anterior forearm (MT-ulna). Maximum voluntary HGS was measured for the dominant hand. Relative HGS was calculated as ratios of HGS to MT-ulna (HGS/MT-ulna, kg/cm), HGS to forearm girth (HGS/forearm-girth, kg/cm), and HGS to body mass (HGS/body mass, kg/kg)...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973380/reference-data-for-jumping-mechanography-in-canadian-children-adolescents-and-young-adults
#19
L Gabel, H M Macdonald, L Nettlefold, D Race, H A McKay
OBJECTIVES: To provide age- and sex-specific reference data for mechanography-derived parameters of muscle function in Canadian children and youth using the single two-legged jump (S2LJ) with hands-on-waist. METHODS: Our sample included 2017 observations from 715 participants (9-21 years; 338 girls). Participants performed three S2LJ with hands-on-waist on a force platform (Leonardo Mechanograph, Novotec). Outcomes were maximum peak power (Pmax), Pmax/mass, peak force/body weight (Fmax/BW), force efficiency, maximum jump height (Hmax), and velocity (Vmax)...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27973379/a-comparison-of-peripheral-imaging-technologies-for-bone-and-muscle-quantification-a-technical-review-of-image-acquisition
#20
A K Wong
The choice of an appropriate imaging technique to quantify bone, muscle, or muscle adiposity needs to be guided by a thorough understanding of its competitive advantages over other modalities balanced by its limitations. This review details the technical machinery and methods behind peripheral quantitative computed tomography (pQCT), high-resolution (HR)-pQCT, and magnetic resonance imaging (MRI) that drive successful depiction of bone and muscle morphometry, densitometry, and structure. It discusses a number of image acquisition settings, the challenges associated with using one versus another, and compares the risk-benefits across the different modalities...
December 14, 2016: Journal of Musculoskeletal & Neuronal Interactions
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