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Journal of Musculoskeletal & Neuronal Interactions

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March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Sarah J Allison, Katherine Brooke-Wavell, Jonathan Folland
High impact exercise programmes can improve bone strength, but little is known about whether this type of training further benefits fracture risk by improving physical function in older people. OBJECTIVES: This study investigated the influence of high impact exercise on balance, muscle function and morphology in older men. METHODS: Fifty, healthy men (65-80 years) were assigned to a 6-month multidirectional hopping programme (TG) and twenty age and physical activity matched volunteers served as controls (CG)...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Xin Ye, Travis W Beck, Nathan P Wages, Joshua C Carr
OBJECTIVES: To examine non-local muscle fatigue (NLMF) in both contralateral homologous and non-related heterogonous muscles for both sexes. METHODS: Ten men and nine women participated in this study. After the familiarization visit, subjects completed four separate randomly sequenced experimental visits, during which the fatiguing interventions (six sets of 30-second maximal isometric contractions) were performed on either their right elbow flexors or knee extensors...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Rosa Kaviani, Irene Londono, Stefan Parent, Florina Moldovan, Isabelle Villemure
The objective of this study was to investigate the effects of mechanical modulation parameters on structural proteins biocomposition and mechanical properties of the growth plate. Establishing these parameters is a crucial step in the development of fusionless treatment of scoliosis. In this study, ulna explants from 4-weeks-old (pubertal) swines were used. The biocomposition was characterized using biochemical content evaluation and immunohistochemistry. Mechanical properties were characterized by fitting the data of the stress relaxation curves using a fibril reinforced biphasic model...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Pamela Trejo, Frank Rauch, Leanne Ward
Children with osteogenesis imperfecta (OI) type VI often have high fracture rates despite the current standard treatment with bisphosphonates. Subcutaneous injections of denosumab have been proposed as an alternative treatment approach, but safety data on denosumab in children are limited. Here we describe fluctuations in bone and mineral metabolism during denosumab treatment in four children with OI type VI who started denosumab (basic protocol: 1 mg per kg body mass every 3 months) between 1.9 and 9.0 years of age, after having received intravenous bisphosphonates previously...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Ahmad H Alghadir, Hamayun Zafar, Shahnawaz Anwer
OBJECTIVE: The present study aimed to evaluate the effect of footwear on standing balance in healthy young adult males. METHODS: Thirty healthy male participants aged 20-30 years were tested for standing balance on the Balance Master on three occasions, including wearing a sandal, standard shoe, or no footwear (barefoot). The tests of postural stability include; "Modified Clinical Test of Sensory Interaction on Balance" (mCTSIB), "Unilateral Stance" (US), and the "Limits of Stability" (LOS)...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Miguel Pishnamaz, Ulrike Schemmann, Christian Herren, Klemens Horst, Philipp Lichte, Frank Hildebrand, Hans-Christoph Pape, Philipp Kobbe
PURPOSE: This review addressed the question of whether minimally invasive surgery after traumatic thoracolumbar spine fractures can reduce paraspinal muscle injury, limit changes in muscular structure and function, and lead to better functional outcome. Special emphasis was given to studies using imaging techniques or electromyography to evaluate the lumbar multifidus muscle structure and function. METHODS: The authors searched the literature in the PubMed/Medline, EMBASE, by cross-referencing and additional hand search...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Baijun Hu, Dawei Gao, Yihe He
OBJECTIVES: The aim of this study is to investigate the efficacy of fibula fixation in the early treatment of osteonecrosis of the femoral head (ONFH). METHODS: 130 patients with ONFH were selected and randomly divided into control group and observation group. Patients in the control group received core decompression treatment, while patients in the observation group received fibula fixation. The local microcirculation was observed by dynamic contrast-enhanced MRI, necrotic volume was measured using MRI, articular surface collapse by using X-ray, McGill pain questionnaire was used to understand and compared the joint pain condition...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Ta-Wei Lai, Hsiao-Li Ma, Meng-Shiunn Lee, Po-Ming Chen, Ming-Chou Ku
OBJECTIVES: Extracorporeal shockwave therapy (ESWT) and corticosteroid injection (CSI) are treatment options for plantar fasciitis. Their clinical outcome comparison remains a debate. Also, the thickness changes of the plantar fascia on objective evaluation under the medium energy ESWT and CSI therapy are elusive. METHODS: A total of 97 patients with chronic plantar fasciitis were enrolled in the randomized prospective trial. Forty-seven patients received extracorporeal shock wave therapy (ESWT), and fifty patients received corticosteroid injection (CSI)...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Youqing Huang
OBJECTIVE: To detect the expression of brain-derived neurotrophic factor (BDNF) in dorsal root ganglion (DRG) of rats with bone cancer pain, and to explore the effects of BDNF and anti-BDNF on pain behavior. METHODS: 40 SD rats were randomly divided into Sham group and Cancer group (n=20). Rats in Sham were injected with PBS into the tibia, while rats in Cancer group were injected with Walker 256 cells to construct rat tibial bone cancer pain model. Rats in Cancer group were further divided into physiological saline (NS) group and anti-BDNF group (n=10) to observe the effects of anti-BDNF on pain behavior in rats with bone cancer pain...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Ricarda Seemann, Frank Graef, Anja Garbe, Johannes Keller, Fan Huang, Georg Duda, Kate Schmidt-Bleek, Klaus-Dieter Schaser, Serafeim Tsitsilonis
INTRODUCTION: The combination of traumatic brain injury (TBI) and long-bone fracture leads to increased formation of callus and mineral density in wild-type (WT) mice. However, this effect was not detected radiologically in leptin-deficient mice. Due to the complex interactions between hormonal and bone metabolism and the important role of leptin in this setting, our aim was to investigate morphologic properties and the tissue composition in the fracture callus comparing WT and leptin-deficient mice...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Maria P Yavropoulou, John G Yovos
Epigenetics, present a new discipline that attempts to explain significant differences in phenotypes among patients with the same disease. In contrast to the other epigenetic mechanisms that modulate gene transcription, non-coding RNAs act at the post-transcriptional level. They directly modulate the gene expression of mRNA genes leading to mRNA target cleavage and degradation and translation repression. Bioinformatic predictions indicate that non coding RNAs may be involved in the regulation of 60% of the coding genes and each non-coding RNA can have multiple target genes, and each gene may be regulated by more than one non-coding RNAs...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
David Scott, Catherine Shore-Lorenti, Lachlan B McMillan, Jakub Mesinovic, Ross A Clark, Alan Hayes, Kerrie M Sanders, Gustavo Duque, Peter R Ebeling
OBJECTIVES: To determine whether associations of calf muscle density with physical function are independent of other determinants of functional decline in overweight and obese older adults. METHODS: This was a secondary analysis of a cross-sectional study of 85 community-dwelling overweight and obese adults (mean±SD age 62.8±7.9 years; BMI 32.3±6.1 kg/m2; 58% women). Peripheral quantitative computed tomography assessed mid-calf muscle density (66% tibial length) and dual-energy X-ray absorptiometry determined visceral fat area...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
Tobias Vogt, Kouki Kato, Nils Flüthmann, Oliver Bloch, Hiroki Nakata, Kazuyuki Kanosue
OBJECTIVE: Motor-related cortical potentials (MRCP) often compared separated muscle activations; however, MRCP preceding combined contraction onsets and relaxation offsets of one consecutive motor task sequence remain to be elucidated. METHODS: Twelve healthy males (27.92±4.33 years, 181.83±7.15 cm, 84.58±7.15 kg) performed 40 submaximal isometric right-limb wrist flexions (i.e. motor task sequences). Each motor task sequence combined timed contractions to and relaxations from distinct torque levels, i...
March 1, 2018: Journal of Musculoskeletal & Neuronal Interactions
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
H Zafar, A H Alghadir, Z A Iqbal
OBJECTIVES: To investigate the effect of different induced head-neck-jaw postures on head-neck relocation error among healthy subjects. METHODS: 30 healthy adult male subjects participated in this study. Cervicocephalic kinesthetic sense was measured while standing, habitual sitting, habitual sitting with clenched jaw and habitual sitting with forward head posture during right rotation, left rotation, flexion and extension using kinesthetic sensibility test. RESULTS: Head-neck relocation error was least while standing, followed by habitual sitting, habitual sitting with forward head posture and habitual sitting with jaw clenched...
December 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
S J Kim, S-N Kim, Y-N Yang, I-S Lee, S-E Koh
BACKGROUND: Despite widespread clinical use of weight bearing exercises to manage low bone mineral density (BMD) in children and adolescents with cerebral palsy (CP), previous studies have reported heterogeneous results on the effect of weight bearing exercise on BMD. PURPOSE: We performed the current meta-analysis to assess the effects of weight bearing exercise on increasing BMD in children who have CP with low BMD. MATERIALS AND METHODS: We searched PubMed, Cochrane, and Embase from inception through to October 2016 for studies that aims to investigate the effect of weight bearing exercise on BMD in children with CP...
December 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
Y Chen, Y Cui, S Chen, Z Wu
OBJECTIVES: Poor sleep quality and short sleep duration are associated with an increased risk for muscle mass reduction. Thus, they may also influence muscle strength. This study aimed to investigate the association between sleep quality and duration, and muscle strength in university students. METHODS: This cross-sectional study comprised 10,125 university students aged 16-30 years. Handgrip strength was measured using a handheld digital dynamometer. Sleep quality and duration were measured using a self-reported questionnaire...
December 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
S El-Shamy, R Alsharif
OBJECTIVES: The objective was to evaluate the effects of virtual reality versus conventional physiotherapy on upper extremity function in children with obstetric brachial plexus injury. METHODS: Forty children with Erb's palsy were selected for this randomized controlled study. They were assigned randomly to either group A (conventional physiotherapy program) or group B (virtual reality program using Armeo® spring for 45 min three times/week for 12 successive weeks)...
December 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
A Gu, R Sellamuthu, E Himes, P J Childress, L M Pelus, C M Orschell, M A Kacena
OBJECTIVES: During the reproductive cycle, altered calcium homeostasis is observed due to variable demand for mineral requirements. This results in increased bone resorption during the time period leading up to parturition and subsequent lactation. During lactation, women will lose 1-3% of bone mineral density per month, which is comparable to the loss experienced on an annual basis post-menopausal. The purpose of this study was to determine the effect of parity on bone formation in middle-aged mice...
December 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
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