journal
MENU ▼
Read by QxMD icon Read
search

Clinics in Colon and Rectal Surgery

journal
https://www.readbyqxmd.com/read/30397396/basic-science-epidemiology-and-screening-for-anal-intraepithelial-neoplasia-and-its-relationship-to-anal-squamous-cell-cancer
#1
REVIEW
Kurt G Davis, Guy R Orangio
Despite the progress made in the reduction of squamous cell carcinoma of the cervix, the incidence of anal squamous cell carcinoma (ASCC) has been increasing since 1992. While it remains an uncommon disease, the prevalence is climbing steadily. Among human immunodeficiency virus (HIV)-infected adults, especially men who have sex with men, ASCC is one of the more common non-AIDS-defining malignancies. The precursor lesion, anal intraepithelial neoplasia (AIN), is prevalent in the HIV-infected population. More than 90% of ASCCs are related to human papilloma virus (HPV), oncogenic types (HPV 16, 18)...
November 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30397395/multidisciplinary-approach-to-the-management-and-treatment-of-anal-dysplasia
#2
REVIEW
Jeffrey Douaiher, Sean J Langenfeld
The incidence of anal intraepithelial neoplasia (AIN) has been increasing over the years. AIN acts as a precursor lesion for anal squamous cell cancer. Factors leading to progression of AIN into malignancy are complex and involve grade of the lesion, human papillomavirus and HIV coinfection, as well as patient-related risk factors such as immunocompromised state and men who have sex with men. The multifaced aspects of this disease make its management challenging, as it involves several disciplines including pathology, primary care, infectious disease, and colorectal specialties...
November 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30397394/so-now-my-patient-has-squamous-cell-cancer-diagnosis-staging-and-treatment-of-squamous-cell-carcinoma-of-the-anal-canal-and-anal-margin
#3
REVIEW
Cindy Kin
Squamous cell carcinomas of the anal canal and the anal margin are rare malignancies that are increasing in incidence. Patients with these tumors often experience delayed treatment due to delay in diagnosis or misdiagnosis of the condition. Distinguishing between anal canal and anal margin tumors has implications for staging and treatment. Chemoradiation therapy is the mainstay of treatment for anal canal squamous cell, with abdominoperineal resection reserved for salvage treatment in cases of persistent or recurrent disease...
November 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30397393/anal-intraepithelial-neoplasia-and-squamous-cell-cancer-of-the-anus
#4
REVIEW
Rebecca E Hoedema
Anal intraepithelial neoplasia (AIN) is the premalignant condition of the anal squamous tissue. It is associated with the human papilloma virus and is considered the transition prior to the invasive anal squamous cell carcinoma. It is typically asymptomatic and can be either an incidental finding after anorectal surgery or identified when high-risk patient populations are screened. Once AIN is diagnosed, the optimal management remains controversial, partly because the natural history of the disease is unclear...
November 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30397392/anal-intraepithelial-neoplasia-from-a-pathologists-point-of-view
#5
REVIEW
Keegan M Lyons, Samantha L Butler
Anal squamous cell carcinoma is a relatively rare diagnosis, but its incidence has continued to rise. Anal squamous cell carcinoma and its precursor lesion, anal intraepithelial neoplasia (AIN), are human papillomavirus (HPV)-associated squamous neoplasias. High-risk HPV subtypes cause cellular proliferation in the anal transformation zone mucosa leading to similar dysplastic changes as seen in the cervix. Unified cytologic and histologic classification systems have emerged for all HPV-associated squamous lesions of the lower anogenital tract due to recent advancements in the understanding of these lesions...
November 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30397391/vaccinations-for-anal-squamous-cancer-current-and-emerging-therapies
#6
REVIEW
John Berry, Sean C Glasgow
Human papillomavirus (HPV) infection is responsible for 4.3% of the global cancer burden. Since 2006, current HPV vaccines have reduced the prevalence of the virus in adolescent girls, reduced the prevalence of genital warts, and been proven to reduce the progression of anal intraepithelial neoplasia in men. Herein, we review the epidemiology, virology, and immunology behind the prophylactic HPV vaccines and current recommendations for its use. We also review future immune therapies being trialed for use against HPV-related cancers including anal cancer...
November 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30397390/anal-intraepithelial-neoplasia-and-squamous-cell-cancer-of-the-anus-past-present-and-future
#7
Fia Yi
No abstract text is available yet for this article.
November 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30397389/fia-yi-md-facs-fascrs-ltcol
#8
Scott R Steele
No abstract text is available yet for this article.
November 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30186053/colorectal-lymphoma-a-review
#9
REVIEW
Nathan D Gay, Andy Chen, Craig Y Okada
Non-Hodgkin lymphoma (NHL) that primarily involves the colon is rare and should be distinguished from the more common systemic nodal lymphoma. It has unique clinical expectations and management consideration. Different histologic subtypes of NHL involve the colon, which varies in the clinical behavior and likelihood of obtaining durable remissions with treatment. This article will review the current understanding of the different histologic subtypes of primary colorectal lymphoma and propose management algorithms...
September 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30186052/small-bowel-and-colorectal-carcinoids
#10
REVIEW
Raphael M Byrne, Rodney F Pommier
Neuroendocrine tumors, or carcinoid tumors, of both the midgut and hindgut are quite rare, but their incidence is increasing. Surgery is the treatment of choice in patients who can tolerate an operation and have operable disease. Options for the treatment of metastatic disease include cytoreductive surgery, somatostatin analogues, interferon α, local liver therapies (hepatic arterial embolization, ablation), chemotherapy, Peptide-Receptor Radionucleotide Radiotherapy, angiogenesis inhibitors, and mammalian target of rapamycin inhibitors...
September 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30186051/gastrointestinal-stromal-tumors-of-the-distal-gastrointestinal-tract
#11
REVIEW
Katherine A Kelley, Raphael Byrne, Kim C Lu
Gastrointestinal stromal tumors (GISTs) are rare in occurrence, but comprise the most common mesenchymal tumors of the gastrointestinal tract and affect between 15 and 20 individuals per million per year. Due to recent advancements in molecular classification of these tumors, medical therapy has provided improved outcomes to a historically surgically managed disease. This review article briefly discusses the molecular characteristics, medical and surgical therapies, and future of GIST management.
September 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30186050/the-role-of-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy-for-appendiceal-tumors-and-colorectal-adenocarcinomas
#12
REVIEW
Michael Kuncewitch, Edward A Levine, Perry Shen, Konstantinos I Votanopoulos
Peritoneal surface disease (PSD) has historically been used interchangeably with the term peritoneal carcinomatosis (PC) and has a dismal natural history. A variety of malignant pathologies, including colorectal and appendiceal primary tumors, can disseminate throughout the peritoneal cavity, leading to bowel obstruction and death. In general, peritoneal spread from high-grade appendiceal and colorectal primaries has the potential of hepatic and distant spread and best classified as PC. Low-grade appendiceal tumors are better categorized as PSD, due to low cellularity, high mucin production, and lack of potential spread outside the peritoneal cavity...
September 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30186049/appendiceal-neoplasms
#13
REVIEW
Quinton M Hatch, Erin W Gilbert
Appendiceal neoplasms are identified in 0.9 to 1.4% of appendiceal specimens, and the incidence is increasing. It has long been professed that neuroendocrine tumors (formerly carcinoids) are the most common neoplastic process of the appendix; recent data, however, has suggested a shift in epidemiology. Our intent is to distill the complex into an algorithm, and, in doing so, enable the surgeon to seamlessly maneuver through operative decisions, treatment strategies, and patient counseling. The algorithm for evaluation and treatment is complex, often starts from the nonspecific presenting complaint of appendicitis, and relies heavily on often subtle histopathologic differences...
September 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30186048/small-bowel-adenocarcinoma
#14
REVIEW
Emerson Y Chen, Gina M Vaccaro
Small bowel adenocarcinoma is a clinically and anatomically distinct gastrointestinal cancer that lacks prospective data to support its optimal management. Patients with inflammatory bowel disease and inherited conditions that cause gastrointestinal polyps are at especially high risk. Due to a lack of effective surveillance programs resulting in missed or delayed diagnoses only when symptoms develop, this disease is generally discovered at an advanced stage. Surgical resection is the only treatment modality with a chance of cure...
September 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30186047/-miscellaneous-tumors-of-the-small-bowel-and-colon-and-rectum
#15
V Liana Tsikitis
No abstract text is available yet for this article.
September 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/30186046/vassiliki-liana-tsikitis-md-mcr-facs-fascrs
#16
Scott R Steele
No abstract text is available yet for this article.
September 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/29942217/uncommon-diverticular-disease
#17
REVIEW
Sanjay Mohanty, Shawn P Webb
This article describes the epidemiology, pathogenesis, diagnosis, and treatment of three rare variants of diverticular disease: cecal and right-sided colonic diverticula, giant colonic diverticula, and small bowel diverticula.
July 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/29942216/evaluation-of-quality-of-life-and-surgical-outcomes-for-treatment-of-diverticular-disease
#18
REVIEW
Mayin Lin, Shankar R Raman
The prevalence of diverticular disease in the Western and industrialized nations has increased over the last century, and our understanding of this disease and its management continues to evolve. In this article, we review the literature regarding the postoperative quality of life (QOL) and functional outcomes following surgical management of diverticulitis, including information regarding bowel function, recurrence of symptoms, and other postoperative sequelae. While objective parameters, such as attacks of diverticulitis, complications, and clinical episodes have been studied, there is a paucity of data on less objective factors, such as overall patient satisfaction after operative management of diverticular disease...
July 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/29942215/management-of-diverticular-bleeding-evaluation-stabilization-intervention-and-recurrence-of-bleeding-and-indications-for-resection-after-control-of-bleeding
#19
REVIEW
Mohammed Iyoob Mohammed Ilyas, Eric J Szilagy
Diverticular bleeding is the most common cause of lower gastrointestinal bleeding with nearly 200,000 admissions in the United States annually. Less than 5% of patients with diverticulosis present with diverticular bleeding and present usually as painless, intermittent, and large volume of lower gastrointestinal bleeding. Management algorithm for patients presenting with diverticular bleeding includes resuscitation followed by diagnostic evaluation. Colonoscopy is the recommended first-line investigation and helps in identifying the stigmata of recent hemorrhage and endoscopic management of the bleeding...
July 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/29942214/surgical-management-of-diverticular-disease-in-the-elective-setting
#20
REVIEW
Jeffrey A Neale
Diverticulosis is a common condition that has increased in prevalence in industrialized countries over the past century. Estimates of developing diverticular disease in the United states range from 5% by 40 years of age up, to over 80% by age 80. It is estimated that approximately 20% of patients with diverticulosis develop diverticulitis over the course of their lifetime. Diverticular disease can be divided into simple and chronic diverticulitis with various sub categories. There are various instances and circumstances where elective resection is indicated for both complex and simple forms of this disease process...
July 2018: Clinics in Colon and Rectal Surgery
journal
journal
38195
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"