journal
https://read.qxmd.com/read/38484958/phenotypic-and-molecular-characterization-of-multi-drug-resistant-klebsiella-spp-isolates-recovered-from-clinical-settings
#1
JOURNAL ARTICLE
Hassan Diab, Kelven Rahy, Tamima Jisr, Mira El Chaar, Edmond Abboud, Sima Tokajian
Klebsiella pneumoniae is a Gram-negative bacterium that colonizes the gastrointestinal tract and nasopharynx with many being linked to nosocomial infections. Extended-spectrum β-lactamases (ESBL)-producing and carbapenem-resistant K. pneumoniae is recognized by the World Health Organization (WHO) as a critical public health concern. In this study, whole-genome sequencing (WGS) - based analysis was performed to understand the molecular epidemiology of multi-drug resistant Klebsiella spp. clinical isolates...
March 12, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38467173/a-novel-metagenomic-approach-uncovers-phage-genes-as-markers-for-increased-disinfectant-tolerance-in-mixed-listeria-monocytogenes-communities
#2
JOURNAL ARTICLE
Agnete Kirstine Karlsmose, Mirena Ivanova, Martin Laage Kragh, Jette Sejer Kjeldgaard, Saria Otani, Christina Aaby Svendsen, Bojan Papić, Irena Zdovc, Taurai Tasara, Roger Stephan, Even Heir, Solveig Langsrud, Trond Møretrø, Paw Dalgaard, Annette Fagerlund, Lisbeth Truelstrup Hansen, Frank M Aarestrup, Pimlapas Leekitcharoenphon
Listeria monocytogenes is an important human pathogen with a high mortality rate. Consumption of contaminated ready-to-eat food is the main mode of transmission to humans. Disinfectant-tolerant L. monocytogenes have emerged, which are believed to have increased persistence potential. Elucidating the mechanisms of L. monocytogenes disinfectant tolerance has been the focus of previous studies using pure cultures. A limitation of such approach is the difficulty to identify strains with reduced susceptibility due to inter-strain variation and the need to screen large numbers of strains and genes...
March 9, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38432594/the-a2-haplotype-of-echinococcus-multilocularis-is-the-predominant-variant-infecting-humans-and-dogs-in-yili-prefecture-xinjiang
#3
JOURNAL ARTICLE
Baoping Guo, Cairen, Jianyong Wu, Wenli Wang, Bingjie Wang, Yuan Ren, Mayire Aizezi, Rongsheng Mi, Li Zhao, Hao Wen
Alveolar echinococcosis (AE), caused by Echinococcus multilocularis, is an important zoonotic disease. Yili Prefecture in Xinjiang is endemic for AE, however the molecular variability of E. multilocularis in this region is poorly understood. In this study, 127 samples were used for haplotypes analysis, including 79 tissues from humans, 43 liver tissues from small rodents, and 5 fecal samples from dogs. Genetic variability in E. multilocularis was studied using complete sequences of the mitochondrial (mt) genes of cytochrome b (cob), NADH dehydrogenase subunit 2 (nad2), and cytochrome c oxidase subunit 1 (cox1), using a total of 3558 bp per sample...
March 1, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38431092/revisiting-genetic-diversity-in-echinococcus-multilocularis-the-role-for-emsb-microsatellite-a-commentary
#4
LETTER
Mohammad Ali Mohammadi, Maid Fasihi Harandi
No abstract text is available yet for this article.
February 29, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38417639/whole-genome-sequence-based-characterization-of-campylobacter-isolated-from-broiler-carcasses-over-a-three-year-period-in-a-big-poultry-slaughterhouse-reveals-high-genetic-diversity-and-a-recurring-genomic-lineage-of-campylobacter-jejuni
#5
JOURNAL ARTICLE
Marc J A Stevens, Roger Stephan, Jule Anna Horlbog, Nicole Cernela, Magdalena Nüesch-Inderbinen
Campylobacter is among the most frequent agents of bacterial gastroenteritis in Europe and is primarily linked to the consumption of contaminated food. The aim of this study was to assess genomic diversity and to identify antimicrobial resistance and virulence genes of 155 Campylobacter isolated from broiler carcasses (neck skin samples) in a large-scale Swiss poultry abattoir over a three-year period. Samples originated from broilers from three different types of farming systems (particularly animal-friendly stabling (PAFS), free-range farms, and organic farms)...
February 26, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38417638/exploring-the-resistome-and-virulome-in-major-sequence-types-of-acinetobacter-baumannii-genomes-correlations-with-genome-divergence-and-sequence-types
#6
JOURNAL ARTICLE
Rachana Banerjee, Stephy Mol Robinson, Abhishake Lahiri, Prateek Verma, Ayushman Kumar Banerjee, Sohom Basak, Kausik Basak, Sandip Paul
The increasing global prevalence of antimicrobial resistance in Acinetobacter baumannii has led to concerns regarding the effectiveness of infection treatment. Moreover, the critical role of virulence factor genes in A. baumannii's pathogenesis and its propensity to cause severe disease is of particular importance. Comparative genomics, including multi-locus sequence typing (MLST), enhances our understanding of A. baumannii epidemiology. While there is substantial documentation on A. baumannii, a comprehensive study of the antibiotic-resistant mechanisms and the virulence factors contributing to pathogenesis, and their correlation with Sequence Types (STs) remains incompletely elucidated...
February 26, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38408586/assessment-of-the-genetic-diversity-of-lymnaeid-gastropoda-pulmonata-snails-and-their-infection-status-with-trematode-cercariae-in-different-regions-of-thailand
#7
JOURNAL ARTICLE
Abdulhakam Dumidae, Chanakan Subkrasae, Jiranun Ardpairin, Supawan Pansri, Chanatinat Homkaew, Chadaporn Nuchjangreed Gordon, Bandid Mangkit, Aunchalee Thanwisai, Apichat Vitta
Lymnaeid snails are some of the most widespread snails and are the first intermediate host of trematode parasites that affect human and livestock health. A full understanding of the genetic relationship of hosts and parasites is of paramount importance for effective parasite management. The present study assessed the prevalence of trematode larvae in lymnaeid snails and examined the genetic diversity of these snails collected across Thailand. We collected 672 lymnaeid snails from 39 locations in 22 provinces of six regions in Thailand...
February 24, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38403035/evolution-of-sars-cov-2-in-the-rhine-neckar-heidelberg-region-01-2021-07-2023
#8
JOURNAL ARTICLE
Christian Bundschuh, Niklas Weidner, Julian Klein, Tobias Rausch, Nayara Azevedo, Anja Telzerow, Jan-Philipp Mallm, Heeyoung Kim, Simon Steiger, Isabelle Seufert, Kathleen Börner, Katharina Bauer, Daniel Hübschmann, Katharina Laurence Jost, Sylvia Parthé, Paul Schnitzler, Michael Boutros, Karsten Rippe, Barbara Müller, Ralf Bartenschlager, Hans-Georg Kräusslich, Vladimir Benes
In January 2021, the monitoring of circulating variants of SARS-CoV-2 was initiated in Germany under the Corona Surveillance Act, which was discontinued after July 2023. This initiative aimed to enhance pandemic containment, as specific amino acid changes, particularly in the spike protein, were associated with increased transmission and reduced vaccine efficacy. Our group conducted whole genome sequencing using the ARTIC protocol (currently V4) on Illumina's NextSeq 500 platform (and, starting in May 2023, on the MiSeq DX platform) for SARS-CoV-2 positive specimen from patients at Heidelberg University Hospital, associated hospitals, and the public health office in the Rhine-Neckar/Heidelberg region...
February 23, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38403034/dissecting-the-genome-sequence-of-a-clinical-isolated-cunninghamella-bertholletiae-z2-strain-with-rich-cytochrome-p450-enzymes-article
#9
JOURNAL ARTICLE
En-Min Zhou, Xin-Ai Chen, Ming-Ming Zhou, Li-Yao Xu, Di Wang, He-Ping Shen, Wei-Qun Xu
Mucormycosis is receiving much more attention because of its high morbidity and extremely high mortality rate in immunosuppressed populations. In this study, we isolated a Cunnignhamella bertholletiae Z2 strain from a skin lesion of a 14 year, 9 months old girl with acute lymphoblastic leukemia who die of infection from the Z2 strain. Genome sequencing was performed after isolation and amplification of the Z2 strain to reveal potential virulence factors and pathogenic mechanisms. The results showed that the genome size of the Z2 strain is 30...
February 23, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38382768/metagenomic-next-generation-sequencing-for-diagnosis-of-fatal-balamuthia-amoebic-encephalitis
#10
JOURNAL ARTICLE
Lixia Qin, Yaqin Xiang, Ziwei Wu, Hainan Zhang, Xiaomei Wu, Qihua Chen
INTRODUCTION: Balamuthia amoebic encephalitis (BAE), caused by Balamuthia mandrillaris, is a rare and life-threatening infectious disease with no specific and effective treatments available. The diagnosis of BAE at an early stage is difficult because of the non-specific clinical manifestations and neuroimaging. CASE DESCRIPTION: A 52-year-old male patient, who had no previous history of skin lesions, presented to the emergency department with an acute headache, walking difficulties, and disturbance of consciousness...
February 19, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38373468/the-analysis-of-complete-genome-sequence-and-comparative-genomics-of-vibrio-parahaemolyticus-lf1113-in-hainan
#11
JOURNAL ARTICLE
Linlin Hu, Aiyun Meng, Zhigang Tu, Shuwen Jia, Qingming Liu, Fuxiao Chen
Vibrio parahaemolyticus is a Gram-negative, halophilic and polymorphic coccobacillus. It is world-widely distributed and has resulted in great economic losses since its first appearance. In this study, a pathogenic strain was isolated from diseased pearl gentian grouper and identified as V. parahaemolyticus based on the sequencing results of 16S rDNA gene. In order to gain a comprehensive understanding of this isolation, the whole genome sequencing was conducted. Phylogenetic analysis of the complete genomes of 16 Vibrio species showed that LF1113, ATCC17802, ATCC33787, 2210633, FORC 004, and 160807 were the most closely related...
February 18, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38367678/comprehensive-analysis-of-antigenic-variations-and-genomic-properties-of-hepatitis-b-virus-in-clinical-samples-in-the-mid-north-east-region-of-bangladesh
#12
JOURNAL ARTICLE
Md Golzar Hossain, Mahfuz Islam, Yusha Araf, Shyamal Kumar Paul, Sharmin Akter, Mohammad Kamruzzaman Khan, Muzahed Uddin Ahmed, Sakirul Khan, Sheikh Mohammad Fazle Akbar, Chitta Ranjan Debnath
This investigation delineates an exhaustive analysis of the clinical, immunological, and genomic landscapes of hepatitis B virus (HBV) infection across a cohort of 22 verified patients. The demographic analysis unveiled a pronounced male bias (77.27%), with patient ages spanning 20 to 85 years and durations of illness ranging from 10 days to 4 years. Predominant clinical manifestations included fever, fatigue, anorexia, abdominal discomfort, and arthralgia, alongside observed co-morbidities such as chronic renal disorders and hepatocellular carcinoma...
February 15, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38367677/polymorphisms-in-the-human-angiotensin-converting-enzyme-gene-ace-linked-to-susceptibility-of-covid-19-and-malaria-infections-in-the-ghanaian-population
#13
JOURNAL ARTICLE
Nancy O Duah-Quashie, Philip Opoku-Agyeman, Marta Lanza, Jose Miguel Rubio
Genetic variations in the human angiotensin converting enzyme gene (ACE) influence ACE enzyme expression levels in humans and subsequently influence both communicable and non-communicable disease outcomes. More recently, polymorphisms in this gene have been linked to susceptibility and outcomes of infectious diseases such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and malaria infections. This study is the first to investigate the genetic diversity of ACE and ACE2 polymorphisms in the Ghanaian population...
February 15, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38365128/epidemiology-and-genetic-diversity-of-theileria-equi-and-babesia-caballi-in-mongolian-horses
#14
JOURNAL ARTICLE
Davaajav Otgonsuren, Tovuu Amgalanbaatar, Sandagdorj Narantsatsral, Batsaikhan Enkhtaivan, Dalantai Munkhgerel, Myagmar Zoljargal, Batbold Davkharbayar, Punsantsogvoo Myagmarsuren, Banzrach Battur, Badgar Battsetseg, Thillaiampalam Sivakumar, Naoaki Yokoyama
Equine piroplasmosis is a tick-borne disease caused by Theileria equi and Babesia caballi in horses. Because of its impact on horse industry, control of this disease is crucial for endemic countries. The control of equine piroplasmosis may be influenced by the genotypic diversity of T. equi and B. caballi. Mongolia, a country with a thriving livestock industry, is endemic for T. equi and B. caballi. However, nationwide epidemiological surveys have not been conducted to determine the current status of infections and genetic diversity of these two parasite species...
February 14, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38354994/first-report-of-anaplasma-spp-ehrlichia-spp-and-rickettsia-spp-in-amblyomma-gervaisi-ticks-infesting-monitor-lizards-varanus-begalensis-of-pakistan
#15
JOURNAL ARTICLE
Shakir Ullah, Jing-Syuan Huang, Afshan Khan, Raquel Cossío-Bayúgar, Nasreen Nasreen, Sadaf Niaz, Adil Khan, Tsai-Ying Yen, Kun-Hsien Tsai, Mourad Ben Said
Ticks pose significant health risks to both wildlife and humans due to their role as vectors for various pathogens. In this study, we investigated tick infestation patterns, tick-associated pathogens, and genetic relationships within the tick species Amblyomma gervaisi, focusing on its prevalence in monitor lizards (Varanus bengalensis) across different districts in Pakistan. We examined 85 monitor lizards and identified an overall mean intensity of 19.59 ticks per infested lizard and an overall mean abundance of 11...
February 13, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38342162/genotypic-analysis-of-hepatitis-e-virus-hev-from-sporadic-symptomatic-cases-in-pakistan
#16
JOURNAL ARTICLE
Momina Ejaz, Ali Zohaib, Muhammad Usman, Muhammad Moaaz Anwar, Hafiz Sajid Khan, Muhammad Ammar, Muhammad Saqib, Sadia Ghani Khan, Muhammad Ammar Athar, Muhammad Khalid Mansoor, Ahsaan Ullah, Mehvish Naseem, Muhammad Hammad Hussain, Aneela Javed
Pakistan is the fifth most populous nation in the world and faces several challenges, including devastating floods, sub-optimal sanitary conditions, clustered accommodations, and unregulated cross-border movements. These drastic population shifts make it vulnerable to the efficient spread of the Hepatitis E virus (HEV). The current study analyzed the genotypic characteristics and variants of the Hepatitis E virus circulating in the population of Pakistan. A total of 75 ELISA-IgM positive samples were collected from three metropolitan cities: Lahore, Peshawar, and Karachi, and subjected to viral RNA extraction...
February 9, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38316245/genetic-diversity-of-g9-g3-g8-and-g1-rotavirus-group-a-strains-circulating-among-children-with-acute-gastroenteritis-in-vietnam-from-2016-to-2021
#17
JOURNAL ARTICLE
Ly Khanh Thi Le, Mai Ngoc Thi Chu, Jacqueline E Tate, Baoming Jiang, Michael D Bowen, Mathew D Esona, Rashi Gautam, Jose Jaimes, Thao Phuong Thi Pham, Huong Thuy Nguyen, Dang D Anh, Nguyen V Trang, Umesh Parashar
Rotavirus group A (RVA) is the most common cause of severe childhood diarrhea worldwide. The introduction of rotavirus vaccination programs has contributed to a reduction in hospitalizations and mortality caused by RVA. From 2016 to 21, we conducted surveillance to monitor RVA prevalence and genotype distribution in Nam Dinh and Thua Thien Hue (TT Hue) provinces where a pilot Rotavin-M1 vaccine (Vietnam) implementation took place from 2017 to 20. Out of 6626 stool samples, RVA was detected in 2164 (32.6%) by ELISA...
February 3, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38309607/detection-of-multiple-recombinations-of-avian-coronavirus-in-south-korea-by-whole-genome-analysis
#18
JOURNAL ARTICLE
Da-Won Kim, Ji-Yun Kim, Dong-Wook Lee, Hyuk-Chae Lee, Chang-Seon Song, Dong-Hun Lee, Jung-Hoon Kwon
Infectious bronchitis virus (IBV), an avian coronavirus, has caused considerable damage to the poultry industry. In Korea, indigenous KM91-like and newly introduced QX-like lineages belonging to the GI-19 lineage have been prevalent despite constant vaccination. In this study, complete genome sequences of 23 IBV isolates in Korea from 2010 to 2020 were obtained using next-generation sequencing, and their phylogenetic relationship and recombination events were analyzed. Phylogenetic analysis based on the S1 gene showed that all isolates belonged to the GI-19 lineage and were divided into five subgroups (KM91-like, K40/09-like, and QX-like II to IV)...
February 1, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38307396/host-genetics-and-the-profile-of-covid-19-in-indigenous-people-from-the-brazilian-amazon-a-pilot-study-with-variants-of-the-ace1-ace2-and-tmprss2-genes
#19
JOURNAL ARTICLE
Eliene Rodrigues Putira Sacuena, Carlos Neandro Cordeiro Lima, Isabella Nogueira Abreu, Lucas Matheus Cavalcante da Silva, Lilian Karen Goes Belleza, Renan Barbosa Lemes, Gilderlânio Santana de Araújo, Hilton Pereira da Silva, Antônio Carlos do Rosário Vallinoto, João Farias Guerreiro
This pilot study aimed to investigate genetic factors that may have contributed to the milder clinical outcomes of COVID-19 in Brazilian indigenous populations. 263 Indigenous from the Araweté, Kararaô, Parakanã, Xikrin do Bacajá, Kayapó and Munduruku peoples were analyzed, 55.2% women, ages ranging from 10 to 95 years (average 49.5 ± 20.7). Variants in genes involved in the entry of SARS-CoV-2 into the host cell (ACE1 rs1799752 I/D, ACE2 rs2285666 C/T, ACE2 rs73635825 A/G and TMPRSS2 rs123297605 C/T), were genotyped in indigenous peoples from the Brazilian Amazon, treated during the SARS-CoV-2 pandemic between 2020 and 2021...
January 31, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38307395/molecular-detection-of-coxiella-burnetii-in-ticks-collected-from-iran
#20
JOURNAL ARTICLE
Ahmad Enferadi, Saeedeh Sarani, Shirin Mohammadipour, Sayyed Jafar Hasani, Afshin Ajdari, Maryam Najafi Asl, Peyman Khademi
The present study was conducted with the aim of investigating the prevalence and genetic structure of Coxiella burnetii in tick samples collected from domestic animals in Hormozgan province146 tick samples were randomly collected from cattle, sheep, goat, camel and dog herds in seven cities of Hormozgan. After the DNA was extracted from each tick sample; Nested-PCR method was used to identify the presence of C. burnetii using IS1111 transposon gene and isocitrate dehydrogenase icd gene. In addition, phylogenetic analysis and tree diagram were constructed based on IS1111 and icd genes...
January 31, 2024: Infection, Genetics and Evolution
journal
journal
38193
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.