Xin Zhao, Chao Chen, Weina Han, Min Liang, Yuanyuan Cheng, Yingjie Chen, Defeng Pang, Haoqi Lei, Xuefei Feng, Shifeng Cao, Zhixiong Li, Jinhui Wang, Yan Zhang, Baofeng Yang
Lung cancer is a leading cause of cancer-related deaths worldwide. Recent studies have identified pyroptosis, a type of programmed cell death, as a critical process in the development and progression of lung cancer. In this study, we investigated the effect of EEBR, a new compound synthesized by our team, on pyroptosis in non-small cell lung cancer cells (NSCLC) and the underlying molecular mechanisms. Our results demonstrated that EEBR significantly reduced the proliferation and metastasis of NSCLC cells in vitro...
January 12, 2024: Journal of Cellular and Molecular Medicine