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American Journal of Alzheimer's Disease and Other Dementias

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https://www.readbyqxmd.com/read/30384769/delirium-and-antipsychotic-medications-at-hospital-intake-screening-to-decrease-likelihood-of-aggression-in-inpatient-settings-among-unknown-patients-with-dementia
#1
Tracy Wharton, Daniel Paulson, Kimberly Burcher, Heather Lesch
For individuals with dementia, disorientation and both external and internal stimuli may trigger behaviors that are difficult to manage or dangerous to health-care providers. Identification of correlational risk factors to aggressive behavior in patients who are unknown to the hospital can allow providers to adapt patient care quickly. Records for patients aged 60+ who spent at least 24 hours at the hospital other than in the psychiatric unit were used (N = 14 080). The first 4000 records and every 10th person who met criteria (N = 5008) were searched for documentation of dementia (n = 505)...
November 1, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30370782/cognitive-stimulating-play-intervention-for-dementia-a-feasibility-randomized-controlled-trial
#2
Daphne Sze Ki Cheung, Bingyu Li, Daniel Wing Leung Lai, Angela Yee Man Leung, Clare Tze Kiu Yu, Ka Tat Tsang
This study investigates the feasibility and the preliminary efficacy of a Cognitive Stimulating Play Intervention on cognitive functions. Thirty older people with early to moderate dementia were recruited from 2 day-care centers, which were randomized into intervention and control groups. The recruitment, attendance, completion rates, and the interview with staff showed that the intervention was feasible. Analysis of covariance results showed that there was a significant difference between groups on memory storage and retrieval functions...
October 28, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30352521/using-video-feedback-at-home-in-dementia-care-a-feasibility-study
#3
Debby L Gerritsen, Raymond T C M Koopmans, Veerle Walravens, Deliane van Vliet
Video feedback at home (VFH) aims to improve the well-being of informal caregivers and persons with dementia by training the caregiver to communicate successfully. This feasibility study had 2 aims: (1) to investigate possible effects regarding VFH, caregiver self-efficacy and the burden experienced, and the frequency of challenging behavior in persons with dementia, and (2) to perform a process evaluation of barriers and facilitators regarding the use of VFH. The respondents were caregivers of home-dwelling persons with dementia participating in VHF (N = 10), a group of caregivers who declined participating in VFH (N = 18), stakeholders (N = 6), and field experts (N = 55)...
October 23, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30343582/musical-features-and-affective-responses-to-personalized-playlists-in-people-with-probable-dementia
#4
Sandra Garrido, Catherine J Stevens, Esther Chang, Laura Dunne, Janette Perz
OBJECTIVES: Personalized music playlists are increasingly being utilized in aged care settings. This study aims to investigate how musical features influence the affective response to music of people with probable dementia. METHODS: A factorial experiment (2 × 2 × 3) was conducted to investigate the influence of tempo (fast, slow), mode (major, minor), and lyrics (none, negative, positive). Ninety-nine people with probable dementia were randomly assigned to 3 conditions, listening to 3 personalized playlists...
October 21, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30328357/reliability-and-validity-of-rowland-universal-dementia-assessment-scale-in-turkish-population
#5
Gizem Ayan, Ceyda Afacan, Burc Cagrı Poyraz, Onur Bilgic, Suna Avci, Hakan Yavuzer, Mehmet Yuruyen, Deniz Suna Erdincler, Burak Ayan, Alper Doventas
BACKGROUND: The aim is to validate Turkish version Rowland Universal Dementia Assessment Scale (RUDAS). METHODS: One hundred forty patients (>65 years) were included. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition -V was used in all patients. Rowland Universal Dementia Assessment Scale was applied for 2 days. Results were compared with Mini-Mental State Examination; reliability, validity, and statistical values were determined. RESULTS: Time validity was verified...
October 17, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30301358/effects-of-hand-exercise-on-eating-action-in-patients-with-alzheimer-s-disease
#6
Li-Li Chen, Hong Li, Xiao-Huan Chen, Shuang Jin, Qiu-Hua Chen, Mei-Rong Chen, Na Li
We aim to investigate whether a popular hand exercise could be used to improve the action of eating in patients with Alzheimer's disease (AD). A 6-month intervention was conducted in 60 patients with AD who live in a nursing home. They were divided into hand exercise and control groups. Patients of the control group maintained their daily routine. The improvement of Edinburgh Feeding Evaluation in Dementia scale in hand exercise group was significantly greater than in the control group ( P = .003). Significant differences in time of autonomous eating and time of simulated eating between patients in the hand exercise and control groups ( P < ...
October 9, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30295038/the-role-of-gender-in-shame-hostility-and-aggression-experienced-by-caregivers-for-patients-with-dementia
#7
Konstantina Avdikou, Charalampos Stefanatos, Marianna Tsatali, Mairy Gouva, Magda Tsolaki
The aim of this study was to investigate the differences between male and female caregivers for patients with dementia in the way they experience various psychosocial parameters such as shame, hostility, and aggression. The sample included 55 caregivers of patients with moderate and severe dementia, whereas the average age was 51 years. Female caregivers were found to experience significantly higher levels of external shame, measured by Other As Shamer scale, than male caregivers, t (53) = 2.54, P < .01...
October 7, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30295037/evaluating-the-benefits-of-the-timeslips-creative-storytelling-program-for-persons-with-varying-degrees-of-dementia-severity
#8
Alyssa A Vigliotti, Vernon M Chinchilli, Daniel R George
OBJECTIVES: To evaluate the benefits of TimeSlips, a group creative storytelling intervention used in residential care settings, on quality of life (QOL), interactions with caregivers, and Mini-Mental State Examination (MMSE) scores for persons with varying degrees of dementia severity. DESIGN: A mixed-methods approach was used weekly over a 6-month period to measure QOL and resident-caregiver relationships. SETTING: A dementia care unit in Pennsylvania...
October 7, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30286613/the-effectiveness-of-reality-orientation-therapy-in-the-treatment-of-parkinson-disease-dementia
#9
Carlos Henrique Ferreira Camargo, Marcelo Araújo Ladeira, Rafael Arthur Serpa, Vinicius Aguiar Jobbins, Carlos Rory Pucci Filho, Leonardo Christiaan Welling, Hélio Afonso Ghizoni Teive
Patients with Parkinson disease dementia (PDD) have deficits resulting mainly from frontostriatal dysfunction. The aim of this study was to assess the effectiveness of reality orientation therapy (ROT) combined with drug therapy (acetylcholinesterase inhibitors) in PDD treatment and compare it with that of drug therapy alone. Patients (n = 12) with a diagnosis of PDD were divided into 2 groups: group A-drug therapy and ROT; group B-drug therapy alone. Reality orientation therapy was applied weekly for 6 months, and patients were assessed during the same period...
October 4, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30278777/effect-of-exercise-on-behavioral-symptoms-and-pain-in-patients-with-dementia-living-in-nursing-homes
#10
Mathieu Maltais, Yves Rolland, Bruno Vellas, Paul-Emile Haÿ, Didier Armaingaud, Philippe Cestac, Laure Rouch, Matteo Cesari, Philipe de Souto Barreto
OBJECTIVES: Examine the effects of a 6-month exercise intervention on neuropsychiatric symptoms, pain, and medication consumption in older people with dementia (PWD) living in nursing homes (NH). METHODS: Ninety-one older PWD living in NH performed a 6-month structured exercise intervention (n = 44) or a social activity intervention (n = 47). Neuropsychiatric symptoms were measured by the neuropsychiatric inventory (NPI), pain was assessed using the Algoplus scale, and dementia-related drug prescriptions were obtained for all participants...
October 3, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30259758/the-cretan-aging-cohort-cohort-description-and-burden-of-dementia-and-mild-cognitive-impairment
#11
Ioannis V Zaganas, Panagiotis Simos, Maria Basta, Stefania Kapetanaki, Symeon Panagiotakis, Irini Koutentaki, Nikolaos Fountoulakis, Antonios Bertsias, George Duijker, Chariklia Tziraki, Nikolaos Scarmeas, Andreas Plaitakis, Dimitrios Boumpas, Christos Lionis, Alexandros N Vgontzas
Our aim was to explore the burden of dementia in the Cretan Aging Cohort, comprised of 3140 persons aged ≥60 years (56.8% women, 5.8 ± 3.3 years formal education, 86.2% living in rural areas) who attended selected primary health-care facilities on the island of Crete, Greece. In the first study phase, a formal diagnosis of dementia had been reached in 4.0% of the participants. However, when selected 505 participants underwent thorough neuropsychiatric evaluation in the second phase of this study (344 with Mini-Mental State Examination [MMSE] <24 and 161 with MMSE ≥24), and results were extrapolated to the entire cohort, the prevalence of dementia and mild cognitive impairment was estimated at 10...
September 27, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30259753/evaluation-of-cognitive-functions-of-individuals-older-than-65-with-diagnosis-of-diabetes
#12
Serap Gokce, Canan Demir Barutcu
This study was conducted in order to examine the level of cognitive function of individuals ≥65 years of age with diabetes. The cross-sectional descriptive design was used. The research was carried out in the diabetes polyclinic of a university hospital between June 2016 and January 2018. The study sample consisted of 91 patients. Data were collected with the scale of Montreal Cognitive Assessment (MoCA). The average score of the patients in the MoCA Scale was found to be 19.61 ± 1.70 (min: 15, max: 26)...
September 27, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30249114/dementia-related-results-of-costs-of-medication-in-older-patients-before-and-after-comprehensive-geriatric-assessment
#13
Ahmet Turan Isik, Pinar Soysal
Changes in the pharmacokinetics and pharmacodynamics of drugs in the presence of certain comorbidities and geriatric syndromes and reduced tolerability of potential drug side effects due to physiological changes with aging lead to difficulties in planning treatments in elderly adults, especially patients with dementia. The Comprehensive Geriatric Assessment has an important role in assessing polypharmacy and optimizing potentially inappropriate medications and potentially prescribing omissions in these patients...
September 24, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30134734/comparison-of-blood-lead-levels-in-patients-with-alzheimer-s-disease-and-healthy-people
#14
Babak Fathabadi, Mohammad Dehghanifiroozabadi, Jan Aaseth, Gholamreza Sharifzadeh, Samaneh Nakhaee, Ali Rajabpour-Sanati, Alireza Amirabadizadeh, Omid Mehrpour
BACKGROUND: It is argued that breakdown of β-amyloid in the brain causes deposition of senescent plaques and therefore Alzheimer's disease (AD). One of the influential factors for increasing level of this protein is exposure to lead. Our aim was to compare blood lead levels (BLLs) between patients with AD and healthy controls. METHODS: This case-control study was performed on all patients with cognitive impairment who were referred to the Neurological Clinic of Birjand in 2016 to 2017...
August 22, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30060670/women-s-pregnancy-life-history-and-alzheimer-s-risk-can-immunoregulation-explain-the-link
#15
Molly Fox, Carlo Berzuini, Leslie A Knapp, Laura M Glynn
BACKGROUND: Pregnancy is associated with improvement in immunoregulation that persists into the geriatric phase. Impaired immunoregulation is implicated in Alzheimer's disease (AD) pathogenesis. Hence, we investigate the relationship between pregnancy and AD. METHODS: Cross-sectional cohort of British women (N = 95). Cox proportional hazards modeling assessed the putative effects of cumulative months pregnant on AD risk and the mutually adjusted effects of counts of first and third trimesters on AD risk...
December 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/30058341/classification-of-alzheimer-s-disease-stages-an-approach-using-pca-based-algorithm
#16
Fayyaz Ahmad, Waqar Mahmood Dar
Early diagnosis of Alzheimer's disease (AD) allows individuals and their health managers to manage healthier medication. We proposed an approach for classification of AD stages, with respect to principal component analysis (PCA)-based algorithm. The PCA has been extensively applied as the most auspicious face-recognition algorithm. For the proposed algorithm, 100 images of 10 children were transformed for feature extraction and covariance matrix was constructed to obtain eigenvalues. The eigenvector provided a useful framework for face recognition...
November 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/29969907/sex-differences-in-the-neuropsychiatric-symptoms-of-patients-with-alzheimer-s-disease
#17
Ye Tao, Matthew E Peters, Lea T Drye, Davangere P Devanand, Jacobo E Mintzer, Bruce G Pollock, Anton P Porsteinsson, Paul B Rosenberg, Lon S Schneider, David M Shade, Daniel Weintraub, Jerome Yesavage, Constantine G Lyketsos, Cynthia A Munro
The aim of this study was to describe sex differences in neuropsychiatric symptoms (NPSs) in patients with Alzheimer's disease (AD). Baseline scores on the Cohen-Mansfield Agitation Inventory, Neurobehavioral Rating Scale-Agitation subscale, and the Neuropsychiatric Inventory from patients with AD enrolled in a multicenter trial of citalopram for the treatment of agitation were analyzed. We found not only that patients with AD having agitation were likely to exhibit many other NPSs but also that the women in this study were more likely to exhibit a broader range of NPS than were the men...
November 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/29772920/a-contagious-disorder-folie-%C3%A3-deux-and-dementia
#18
Gabriele Cipriani, Noha Abdel-Gawad, Sabrina Danti, Mario Di Fiorino
BACKGROUND: Folie à deux is a clinical condition that was first described in 19th century. It is a psychotic disorder in which two closely associated individuals share a similar delusional system. OBJECTIVES: The aim of this article is to review the nosological significance of folie à deux and to explore the disorder among patients with dementia. METHODS: Medline and Google Scholar searches were conducted for relevant articles, chapters, and books published before 2017...
November 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/29874918/danger-in-the-air-air-pollution-and-cognitive-dysfunction
#19
Gabriele Cipriani, Sabrina Danti, Cecilia Carlesi, Gemma Borin
BACKGROUND: Clean air is considered to be a basic requirement for human health and well-being. OBJECTIVE: To examine the relationship between cognitive performance and ambient pollution exposure. METHODS: Studies were identified through a systematic search of online scientific databases, in addition to a manual search of the reference lists from the identified papers. RESULTS: Air pollution is a multifaceted toxic chemical mixture capable of assaulting the central nervous system...
September 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/29847992/differentiated-regional-homogeneity-in-progressive-mild-cognitive-impairment-a-study-with-post-hoc-label
#20
Suping Cai, Yubo Wang, Yafei Kang, Haidong Wang, Hyejin Kim, Karen M von Deneen, Meiping Huang, Yuanyuan Jiang, Liyu Huang
PURPOSE: Mild cognitive impairment (MCI) is considered to be the clinical transition stage between patients with cognitively intact geriatrics and Alzheimer's disease (AD). When observed longitudinally, however, a certain proportion of patients with MCI are expected to revert to a cognitively intact state (MCI_R) while others either remain in the MCI state (MCI_S) or deteriorate into AD (MCI_P). It is worthwhile to investigate the divergence in the brain activities of these MCI groups with different post hoc labels...
September 2018: American Journal of Alzheimer's Disease and Other Dementias
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