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American Journal of Alzheimer's Disease and Other Dementias

Vishal Bali, Satabdi Chatterjee, Michael L Johnson, Hua Chen, Ryan M Carnahan, Rajender R Aparasu
OBJECTIVE: This study evaluated the risk of cognitive decline associated with paroxetine use in elderly nursing home patients with depression. METHODS: A retrospective cohort study was conducted using the 2007 to 2010 Medicare Part D claims and minimum data set (MDS) data involving new users of paroxetine and other selective serotonin reuptake inhibitors (SSRIs). The primary outcome was MDS Cognition Scale. The repeated-measures mixed model was used to examine the effect of paroxetine on cognition after controlling for other factors...
October 20, 2016: American Journal of Alzheimer's Disease and Other Dementias
Gabriele Cipriani, Cecilia Carlesi, Claudio Lucetti, Sabrina Danti, Angelo Nuti
BACKGROUND: Eating problems and dietary changes have been reported in patients with dementia. OBJECTIVES: The aim of this article is to explore the generalized problems with nutrition, diet, feeding, and eating reported among patients with dementia. METHODS: Medline and Google Scholar searches were conducted for relevant articles, chapters, and books published before 2016. Search terms used included behavioral and psychological symptoms of dementia, dementia, dietary changes, eating behavior...
October 18, 2016: American Journal of Alzheimer's Disease and Other Dementias
Charles Van Liew, Maya S Santoro, Jody Goldstein, Shea Gluhm, Paul E Gilbert, Jody Corey-Bloom
We sought to investigate whether the Montreal Cognitive Assessment (MoCA) could provide a brief assessment of recall and recognition using Huntington disease (HD) and Alzheimer disease (AD) as disorders characterized by different memory deficits. This study included 80 participants with HD, 64 participants with AD, and 183 community-dwelling control participants. Random-effects hierarchical logistic regressions were performed to assess the relative performance of the normal control (NC), participants with HD, and participants with AD on verbal free recall, cued recall, and multiple-choice recognition on the MoCA...
September 26, 2016: American Journal of Alzheimer's Disease and Other Dementias
Zhao Yang, Hunter K Holt, Jin-Hu Fan, Li Ma, Ying Liu, Wen Chen, Peter Como, Lin Zhang, You-Lin Qiao
To explore the optimal cutoff score for initial detection of Alzheimer's Disease (AD) through the Chinese version of Mini-Mental State Examination (CMMSE) in rural areas in China, we conducted a cross-sectional study within the Linxian General Population Nutritional Follow-up study. 16,488 eligible cohort members participated in the survey and 881 completed the CMMSE. Among 881 participants, the median age (Interquartile range) was 69.00 (10.00), 634 (71.92%) were female, 657 (74.57%) were illiterate, 35 (3...
September 22, 2016: American Journal of Alzheimer's Disease and Other Dementias
Lori Schindel Martin, Leslie Gillies, Esther Coker, Anne Pizzacalla, Maureen Montemuro, Grace Suva, Victoria McLelland
Education is needed for enhanced capacity of acute hospitals to provide dementia care. A nonrandomized controlled, repeated-measures design was used to evaluate a dementia education program delivered to an intervention group (IG, n = 468), compared to a wait-listed group (n = 277), representing separate sites of a multisite hospital. Participants completed self-efficacy for dementia and satisfaction measures and provided written descriptions of dementia care collected at baseline, postintervention (IG only), and at 8-week follow-up...
September 22, 2016: American Journal of Alzheimer's Disease and Other Dementias
Sandra Fitzler, Paul Raia, Fredrick O Buckley, Mei Wang
The purpose of the project, Centers for Medicare & Medicaid Services (CMS) Innovation study, was to evaluate the impact on 12 quality measures including 10 Minimum Data Set (MDS) publicly reported measures and 2 nursing home process measures using habilitation therapy techniques and a behavior team to manage dementia-related behaviors. A prospective design was used to assess the changes in the measures. A total of 30 Massachusetts nursing homes participated in the project over a 12-month period. Project participation required the creation of an interdisciplinary behavior team, habilitation therapy training, facility visit by the program coordinator, attendance at bimonthly support and sharing calls, and monthly collection of process measure data...
September 20, 2016: American Journal of Alzheimer's Disease and Other Dementias
Drew Hager, Andrew Kirk, Debra G Morgan, Chandima Karunanayake, Megan E O'Connell
To determine the predictors of cognitive decline in a rural and remote population with Alzheimer's disease (AD), we examined the association between cognitive change and sociodemographic, clinical, and functional data at the initial day of diagnosis. Simple linear regression analysis and multiple regression analysis were used to determine the predictors of cognitive decline as measured by the difference in the Mini-Mental State Examination over 1 year. Our sample included 72 patients with AD. Age at the clinic day appointment was 75...
August 28, 2016: American Journal of Alzheimer's Disease and Other Dementias
Howard K Butcher, Jean K Gordon, Ji Woon Ko, Yelena Perkhounkova, Jun Young Cho, Andrew Rinner, Susan Lutgendorf
This study tested the effect of written emotional expression on the ability to find meaning in caregiving and the effects of finding meaning on emotional state and psychological burden in 91 dementia family caregivers. In a pretest-posttest design, participants were randomly assigned to either an experimental or a comparison group. Experimental caregivers (n = 57) wrote about their deepest thoughts and feelings about caring for a family member with dementia, whereas those in the comparison group (n = 34) wrote about nonemotional topics...
August 28, 2016: American Journal of Alzheimer's Disease and Other Dementias
Barbara Resnick, Ann Kolanowski, Kimberly Van Haitsma, Marie Boltz, Elizabeth Galik, Alice Bonner, Erin Vigne, Lauren Holtzman, Paula M Mulhall
Behavioral and psychological symptoms of dementia are common in nursing home residents, and the Centers for Medicare and Medicaid Services now require that nonpharmacological interventions be used as a first-line treatment. Few staff know how to implement these interventions. The purpose of this study was to pilot test an implementation strategy, Evidence Integration Triangle for Behavioral and Psychological Symptoms of Dementia (EIT-4-BPSD), which was developed to help staff integrate behavioral interventions into routine care...
November 2016: American Journal of Alzheimer's Disease and Other Dementias
Ahmet Turan Isik, Pinar Soysal, Cansu Usarel
OBJECTIVE: The present study was designed to evaluate the effect of acetylcholinesterase inhibitor (AchEI) therapy on balance, gait, and orthostatic hypotension (OH) in elderly patients with Alzheimer's disease (AD). METHODS: A total of 102 elderly patients with AD have been recently diagnosed and were treated with AchEI and underwent comprehensive geriatric assessment at baseline and at the end of the sixth month. RESULTS: Timed Up and Go test and Tinetti Performance-Oriented Mobility Assessment values and the prevalence of OH were not different at the end of the sixth month versus baseline (P > ...
November 2016: American Journal of Alzheimer's Disease and Other Dementias
Cathleen D Zick, Ken R Smith, Robert N Mayer
BACKGROUND: We assess whether a family history of Alzheimer's disease (AD) is associated with the odds that healthy family members' engage in retirement planning activities. METHODS: This is a cross-sectional study utilizing individual-level data from the Utah Population Database that have been linked to Medicare records and to responses from a retirement planning survey. Engagement in 3 retirement planning activities was estimated as a function of the number of parents and grandparents diagnosed with AD along with a set of fundamental socioeconomic and demographic covariates...
September 2016: American Journal of Alzheimer's Disease and Other Dementias
Robin Tarter, George Demiris, Kenneth Pike, Karla Washington, Debra Parker Oliver
INTRODUCTION: At the end of life, patients with dementia often experience high levels of pain due to complex interplay of disease processes and numerous barriers to symptom management. In the hospice setting, informal caregivers play an essential role in pain management. This study describes their experience managing pain in hospice patients with dementia. METHODS: We conducted a qualitative analysis of audio-recorded interviews with informal caregivers of hospice patients with dementia who had chosen pain as the challenge they wanted to work on within a problem-solving therapy intervention...
September 2016: American Journal of Alzheimer's Disease and Other Dementias
Heehyul Moon, Aloen L Townsend, Peggye Dilworth-Anderson, Carol J Whitlatch
PURPOSE: The goal of this study was to explore predictors of discrepancy between reports of caregivers (CGs) and care recipients (CRs) with mild-to-moderate dementia about CRs' quality of life (QOL). DESIGN AND METHODS: This study was a secondary analysis of cross-sectional data drawn from a study of 200 care dyads of CRs with mild-to-moderate dementia and their primary family CGs. Paired t test, ordinary least squares multiple regression, and binary logistic regression were used for the analyses...
September 2016: American Journal of Alzheimer's Disease and Other Dementias
John Zeisel, Barry Reisberg, Peter Whitehouse, Robert Woods, Ad Verheul
Dementia is a major medical and social scourge. Neither pharmacological nor nonpharmacological interventions and treatments have received sufficient funding to be meaningful in combatting this tsunami. Because the term-"nonpharmacological"-refers to what these interventions are not, rather than what they are, nonpharmacological treatments face a special set of challenges to be recognized, accepted, funded, and implemented. In some ways, the current situation is analogous to using the term "nonhate" to mean "love...
September 2016: American Journal of Alzheimer's Disease and Other Dementias
Zoe Blake Samson, Monica Parker, Clinton Dye, Kenneth Hepburn
Dementia family caregivers display significant rates of psychological and physical symptoms. African Americans (AAs) are disproportionately affected by dementia. African American caregivers display unique patterns of symptomology and responses to interventions designed to promote caregiver well-being. This study analyzed qualitative focus group data from 32 AA caregivers to explore how issues of race and culture may be incorporated into a culturally sensitive intervention for AA dementia family caregivers. Caregivers were asked scripted questions about their caregiving experiences and to suggest alterations to an existing psychoeducation program...
September 2016: American Journal of Alzheimer's Disease and Other Dementias
Sung-In Jang, Hong-Chul Bae, Jaeyong Shin, Suk-Yong Jang, Seri Hong, Kyu-Tae Han, Eun-Cheol Park
INTRODUCTION: Dementia is the leading cause of disability worldwide in the elderly individuals. Although prior studies have examined psychiatric symptoms in dementia caregivers, few studies have examined physician-diagnosed depression in the family caregiver of a patient with dementia. METHODS: We used data from 457 864 respondents from the Korea Community Health Survey. We used logistic regression to examine the relationship between physician-diagnosed depression and cohabitation with a patient with dementia...
September 2016: American Journal of Alzheimer's Disease and Other Dementias
Tatjana Bulat, Michael V Kerrigan, Meredeth Rowe, William Kearns, Jeffrey D Craighead, Padmaja Ramaiah
BACKGROUND: Persons with dementia are at risk of a missing incident, which is defined as an instance in which a demented person's whereabouts are unknown to the caregiver and the individual is not in an expected location. Since it is critical to determine the missing person's location as quickly as possible, we evaluated whether commercially available tracking technologies can assist in a rapid recovery. METHODS: This study examined 7 commercially available tracking devices: 3 radio frequency (RF) based and 4 global positioning system (GPS) based, employing realistic tracking scenarios...
September 2016: American Journal of Alzheimer's Disease and Other Dementias
Marie Y Savundranayagam, Jovana Sibalija, Emma Scotchmer
Long-term care staff caregivers who are person centered incorporate the life history, preferences, and feelings of residents with dementia during care interactions. Communication is essential for person-centered care. However, little is known about residents' verbal reactions when staff use person-centered communication. Accordingly, this study investigated the impact of person-centered communication and missed opportunities for such communication by staff on resident reactions. Conversations (N = 46) between staff-resident dyads were audio-recorded during routine care tasks over 12 weeks...
September 2016: American Journal of Alzheimer's Disease and Other Dementias
Areum Han, Jeff Radel
This qualitative study explored spousal caregiver perspectives on the experience and impact of a person-centered social program for partners with dementia. Interviews with 5 caregivers and the spouses with dementia were conducted 7 to 8 months after the program ended to explore the sustained impact of the program. Interpretative phenomenological analysis was used to support in-depth exploration of interviews. Three themes emerged including benefits of the program for caregivers, initial expectations and later perspectives of caregivers about the program, and conflicting values and perspectives between caregivers and the spouses...
September 2016: American Journal of Alzheimer's Disease and Other Dementias
Stefano Colangeli, Maddalena Boccia, Paola Verde, Paola Guariglia, Filippo Bianchini, Laura Piccardi
Cognitive reserve (CR) has been defined as the ability to optimize or maximize performance through differential recruitment of brain networks. In the present study, we aimed at providing evidence for a consistent brain network underpinning CR in healthy and pathological aging. To pursue this aim, we performed a coordinate-based meta-analysis of 17 functional magnetic resonance imaging studies on CR proxies in healthy aging, Alzheimer's disease (AD), and mild cognitive impairment (MCI). We found that different brain areas were associated with CR proxies in healthy and pathological aging...
August 2016: American Journal of Alzheimer's Disease and Other Dementias
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