Filippo Bagnoli, Giuditta Pini, Bachisio Ziccheddu, Arturo Bonometti, Silvia Alberti-Violetti, Luigia Venegoni, Giuseppe Isimbaldi, Matteo Claudio Da Vià, Angela Ferrari, Luca Baldini, Antonino Neri, Francesco Onida, Niccolò Bolli, Emilio Berti
Intravascular large B-cell lymphoma (IVLBCL) is a rare aggressive extranodal non-Hodgkin lymphoma. The predominant, if not exclusive, growth of neoplastic cells within the lumina of small-sized vessels represents the hallmark of the disease. Diagnosis is challenging due to the absence of marked lymphadenopathy, the highly heterogeneous clinical presentation, and the rarity of the condition. Clinical presentation is characterized by variable combinations of nonspecific signs and symptoms (such as fever and weight loss), organ-specific focal manifestations due to altered perfusion, and hemophagocytic syndrome...
March 5, 2024: Clinical and Experimental Medicine