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Advances in Gerontology, Uspekhi Gerontologii

A A Ursta, E I Kharkov, M M Petrova, O V Ursta, A R Kotikov, A N Kiselev
This review devoted to actual medical problem that exists at a crossroad of cardiology, nephrology and radiology. Contrast induced nephropathy (CIN) is an important medical issue and its frequency is increasing last years. This disease may account for severe complications, including renal failure and even fatal outcome. We investigated contemporary sources to present epidemiology, pathogenesis, diagnosis, treatment and prophylaxis of CIN.
2017: Advances in Gerontology, Uspekhi Gerontologii
T V Orlyk, N V Grygorieva, V V Povoroznyuk
We have analyzed the vertebral pain syndrome (VPS) rate in 2 844 women aged 40-89 years, divided into groups according to the period of life (reproductive, perimenopausal and postmenopausal (PMP)) and evaluated the relationship between VPS frequency and indices of bone mineral density (BMD). It was found that the frequency of VPS during different physiological periods of woman life ranges from 84,1 to 94,4 %, with significant increase when the PMP period is more than 20 years compared with women in reproductive and early postmenopausal periods...
2017: Advances in Gerontology, Uspekhi Gerontologii
M B Polyanskiy, D P Nazarenko, T A Ishunina
In the present study the analysis of dynamics of basic laboratory parameters of patients with acute cholecystitis (AC) in the four age groups subdivided according to the WHO classification into young, middle age, elderly and senile was carried out. The most pronounced changes were found in the senile age group in which the AC was accompanied by the decreased number of erythrocytes, low hemoglobin and total protein, leukocytosis, lower percentage of lymphocytes and the highest levels of ALT, AST, bilirubin and urea...
2017: Advances in Gerontology, Uspekhi Gerontologii
I B Antonov, K L Kozlov, N S Linkova, E M Paltseva, E O Kykanova
The review considers various aspects of myocardium aging in normal and dilated cardiomyopathy (DC). There is a partial fibrosis of the heart tissue due to accumulation of collagen type 1, and accumulation of amyloid during normal aging. Men myocardial aging is accompanied by loss of cardiomyocytes and increased volume of the remaining cells, whereas in women this effect is absent. There is an expression of nuclear proteins decrease (lamin A and C), the accumulation of lipofuscin, increased content of reactive oxygen species, reduction of protein synthesis Sirt1 in cardiomyocytes with aging...
2017: Advances in Gerontology, Uspekhi Gerontologii
A S Pushkin, A A Yakovlev, T A Akhmedov, S A Rukavishnikova, G A Ryzhak
Article is about troponin I testing by high sensitive method in healthy population group. 165 people (employees of hospital) were examined, 71 % - women and 29 % - men. Inclusion criteria were as follows: absence of active complaints at the time of health examination and during the previous 30 days. All the examinees were divided into three age groups: 18-34 years (middle age, I period), 35-54 years (middle age, II period), above 55 years (old age). Research of correlation between cardiac troponin I and age of healthy population group was the main aim of investigation...
2017: Advances in Gerontology, Uspekhi Gerontologii
V V Vnukov, R V Sidorov, N P Milutina, A A Ananyan, D Yu Gvaldin, A B Sagakyants, I F Shlyk, E P Talalaev
76 patients with coronary heart disease (who had undergone coronary artery bypass grafting) were examined to investigate the role of pro-inflammatory cytokines and enzymes involved in redox regulation, in the mechanisms of development of systemic inflammatory response syndrome. Patients were divided into 2 groups: 1st - patients with coronary heart disease, who as a result of clinical trials has not been set postpericardiotomy syndrome; 2nd - patients with coronary heart disease who have been diagnosed postpericardiotomy syndrome...
2017: Advances in Gerontology, Uspekhi Gerontologii
V E Pashkovskiy, A G Sofronov, A E Dobrovolskaya, G A Prokopovich
The aim of this study is to identify psychosocial characteristics of older people who attempted suicide by self-poisoning. A total of 44 older people with suicide attempts by self-poisoning was examined, 12 of whom were male and 32 were female, their average age was 71,9+10,8. The comparison group consisted of 53 young people - 19 males and 34 females, their average age was 26,6+4,4. In both groups dominated deliberate self-poisoning with antiepileptic, sedative, soporific, Antiparkinson and psychotropic drugs (40,9 % vs 47,2 %, p>0,05)...
2017: Advances in Gerontology, Uspekhi Gerontologii
U Bayer, O S Glazachev, R Likar, M Burtscher, W Kofler, G Pinter, H Stettner, S Demschar, B Trummer, S Neuwersch
For improvements in exercise tolerance and cognitive function in geriatric patients Multimodal training programs (MTP) are used as combination of physiotherapy, occupational therapy and cardiovascular training. Intermittent Hypoxic-Hyperoxic Training (IHHT), a modified type of intermittent hypoxic training (IHT) is proposed to be included in MTP to elicit more pronounced beneficial effects in exercise tolerance and cognitive functions of geriatric patients likely by an additional pathway than a single MTP. Thirty four patients of the Geriatric Day Clinic aged between 64 and 92 years participated in the placebo controlled clinical trial...
2017: Advances in Gerontology, Uspekhi Gerontologii
L Van Eijk, S A Zwijsen, D Keeser, J M Oosterman, O Pogarell, H J Engelbregt
This pilot study attempted to study the applicability of neurofeedback for elderly persons living in nursing homes. We hypothesized an improve of cognitive functioning and the independence in daily life (IDL) of elderly people by using low beta (12-15HZ) EEG neurofeedback training (E-NFT). The participants (active E-NFT group, n=10; control group, n=6) were community living elderly women without dementia. Neurofeedback training was adjusted ten times within 9 weeks, with a training duration of 21 minutes by use of a single electrode, which was centrally placed on the skull surface...
2017: Advances in Gerontology, Uspekhi Gerontologii
I A Grigoryeva, V N Kelasev
In the article we discussed the processes of awareness of the place of elderly people in modern society, elaboration of adequate relation to global aging and elderly themselves are still going in social sciences. These processes are expressed in a clash of archaic stereotypes and new approaches which changed social and age structure requires. Not only elderly people are providers of archaic stereotypes, but scientific institutions and practices as well. Reorientation of science, media and social policy towards study and realization of «postponed aging» opportunities is needed...
2017: Advances in Gerontology, Uspekhi Gerontologii
O N Tkacheva, N K Runikhina, V S Ostapenko, N V Sharashkina, E A Mkhitaryan, U S Onuchina, S N Lysenkov
For screening frailty in daily practice, we developed the questionnaire relating issues of weight loss, impaired vision and hearing, injuries related to falls, mood decline, cognitive impairment, urinary incontinence, and mobility difficulties. 356 outpatients from Moscow were included in the study (mean age 74,9±6,1 years, women - 80,4 %). Patients were interviewed using the questionnaire and underwent a comprehensive geriatric assessment. The phenotype model of frailty was determined by L. Fried criteria, the frailty index model - by K...
2017: Advances in Gerontology, Uspekhi Gerontologii
O N Tkacheva, N K Runikhina, V S Ostapenko, N V Sharashkina
Although geriatric syndromes are widespread, they often remain undiagnosed leading to the development of adverse outcomes. For the prompt detection of the most common geriatric syndromes in primary care we have created seven issues related to weight loss, vision and hearing impairments, falls, mood disorder, cognitive impairment, urinary incontinence, and the difficulties in walking. We believe that using of these questions will allow physicians to focus on addressing the important health problems associated with age and will produce the selection of patients for comprehensive geriatric assessment...
2017: Advances in Gerontology, Uspekhi Gerontologii
O A Shavlovskaya
Social activity of older people can be associated with deterioration as motor function (ability to stand on one leg, walk heel to toe), motor dexterity (grasping power, the tapping-test). At the same time, deterioration in motor functions is due to the fading of social activity, and as a result, deterioration of cognitive functions. Greater involvement in social life can slow the deterioration of motor functions and to maintain daily quality of life.
2017: Advances in Gerontology, Uspekhi Gerontologii
E V Karol, R K Каntemirova
The article presents data on the main desadaptive syndromes have disabilities due to cerebrovascular diseases in the elderly according to the results of analysis of medical expert documents the Bureau of medico-social examination of Saint-Petersburg in the period from 2010 to 2014. The characteristics of the level, structure, dynamics and distribution according to groups of disability due to cerebrovascular diseases in retirement were shown; clinical expert in the features of the population of older people with disabilities due to cerebrovascular diseases were analyzed...
2017: Advances in Gerontology, Uspekhi Gerontologii
V S Myakotnykh, T A Borovkova
The article presents the results of a comparative study of clinical symptoms of syndrome of emotional burnout among 84 working in the specialty physician of older women and 48 officially ceasing operations in this specialty. The findings suggest that burnout can take place among representatives of older age and more it is continued, provided professional activities. The cessation of the work activities leads to stress, often with the subsequent development post-traumatic stress disorder and stress-induced diseases...
2017: Advances in Gerontology, Uspekhi Gerontologii
V V Myakotnyh, L S Khodasevich
The analysis of the study results of remote training effect of physical training and sports in the age range including the later periods of human ontogenesis, from the point of oxidative stress theory. To study the characteristics of developmental variability of the functional state of the organism, a comparative study of the functional state of the body at different modes of physical activity in different age stages of development was carried out: from sports veterans, remain actively locomotor activity after the termination of sports career; former athletes, leading a sedentary lifestyle; persons engaged in improving the forms of physical exercise; as well as persons who had not engaged in regular physical activity...
2017: Advances in Gerontology, Uspekhi Gerontologii
N V Zemskaya, M V Shaposhnikov, A A Moskalev
In the present study, we investigated the relationship of lifespan with different characteristics of the life history (length of the developmental period, imago body weight, fecundity) and stress resistance (response to oxidative stress, hyperthermia, starvation, and ionizing radiation) in flies of 12 species of the Drosophila genus. It was shown, that D. virilis has the highest maximum lifespan, but the lifespan of D. kikkawai was lowest. The investigated features have a positive (length of the developmental period, imago body weight, stress resistance) or negative (fecundity) correlation with species lifespan...
2017: Advances in Gerontology, Uspekhi Gerontologii
L M Berstein
Processes important for hormone-mediated carcinogenesis are present on different, even very early, ontogenesis stages. Early shifts in hormone-metabolic status often display opposite correlations with the risk of most common age-associated non-communicable pathologies (namely, hormone-dependent cancers and cardiovascular diseases). Additional known contradiction is the raise of reproductive system tumors incidence in the age associated with lower production of mitogenic hormones. Consequently, one should take into account production of steroids in target tissues themselves, recognize the importance of progenotoxic effect, which, apart from mitogenic function, is characteristic for estrogens and their derivatives, as well as the role of endocrine-genotoxic switchings forming so called basic triad, which is born under the influence of age-associated endocrine shifts and environmental factors...
2017: Advances in Gerontology, Uspekhi Gerontologii
A A Viktorov, V D Gladkikh, E E Morozova
The aim of the study is to assess the adequacy of model representations, accepted in the kinetic theory of aging of living systems, the analysis of the experimental data obtained on dogs and fruit flies. The work is illustrated by applying the need to develop a mathematical model of the kinetic theory of aging to describe the probability density of death, probability of death, the average duration of life of the considered biological systems in the natural conditions of existence, as well as for dogs with limited time and chronic RA-diciannove impact, and for Drosophila - high external temperature...
2017: Advances in Gerontology, Uspekhi Gerontologii
V N Anisimov, V Yu Serpov, A V Finagentov, V Kh Khavinson
This article is a 1st part of the analytical review, focused on a new step in development of geriatrics in Russia. Creation of state system geriatric care as important part of state politics in the area of enhancement of quality of life was proved. General aspects of improvement of social support of disable elderly persons in condition of restricted budget and interagency separation was presented. Establishment of unified system of medical social support and gerotechnologies for the elderly was substantiated, as a mechanism facilitated life activity and decreasing of demographic loading on economic status of regions of Russian Federation...
2017: Advances in Gerontology, Uspekhi Gerontologii
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