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Advances in Gerontology, Uspekhi Gerontologii

V A Byvaltsev, A A Kalinin, A K Okoneshnikova
The aim of the study was a comparative analysis of the clinical and radiographic effectiveness of the use of interbody fusion and open pedicle screw stabilization of simultaneous and new minimally invasive techniques facet fixation system «Facet Wedge» in the treatment of degenerative diseases of the lumbar spine in elderly patients. The study included 39 elderly patients (older than 60), which carries out the transforaminal interbody fusion Cage «T-pal»: open transpedicaular stabilization was used in 1st group (n=23), ipsilateral open transpedicular stabilization with contralateral transfaset installing titanium Cage «facet Wedge» -in 2nd group (n=16)...
2017: Advances in Gerontology, Uspekhi Gerontologii
V I Dolgova, N V Mamylina
Objective - to create and hold psychophysiological monitoring elderly organism female teachers in the school year dynamics. The study was conducted with the participation of 30 female teachers aged 60-61 years at the beginning of the year (background level) and 5, and 9 months of teaching in the school. We studied 5-minute recording portions of the electrocardiogram using a program «Poly-Spectrum-Rhythm» (the limited liability company «Neurosoft»); lung function - using the apparatus «Spirosoft-5000»; psycho-emotional state of teachers in the dynamics of the school year - on the method of SUN (state of health, activity, mood)...
2017: Advances in Gerontology, Uspekhi Gerontologii
T V Shuteeva, N K Gorshunova
In the formation of a common age-associated pathological process in patients with Parkinson's disease along with movement disorders so-called «non-motorized» clinical symptoms (including anxiety and depression) play an important role. These pathological manifestations can reduce the quality of life of the patient and require specific therapeutic measures. The picker is the use of drugs - antidepressants. The article discusses the opportunity for the effective and safe use of such drug - sertraline combined with basic therapy, which is widely used in Parkinson's disease...
2017: Advances in Gerontology, Uspekhi Gerontologii
V G Belov, Yu A Parfenov, M A Vasilevskaya, S A Parfenov, K V Sapozhnikov, A L Kovalenko, V A Zaplutanov
We conducted a study of 220 patients in polyclinic № 91 in St. Petersburg. It was revealed that elderly patients with osteochondrosis are characterized by a high prevalence and severity of osteochondrosis against the background of metabolic disorders in the structures of the spine. At the same time, the actual condition of the spine does not always determine the severity of the pain syndrome. The effect of osteochondrosis on the development of comorbid pathology has been clarified. The ways of correction of the clinical and psychophysiological status of elderly patients with osteochondrosis such as appointment of Cytoflavin, behavioral therapy and biofeed back therapy are suggested...
2017: Advances in Gerontology, Uspekhi Gerontologii
O B Asriyan, T V Kapustina, D S Lyukshina, R V Kadyrov
The aim of the work is to analyze the prevalence and severity of the psychological characteristics of the compliance of elderly women being at the social institution in comparison with the same age group living in the family and receiving support from relatives. The experimental group of the research consisted of 27 women at the age of 70-79 years being at the social institution, named Regional State Autonomous Institution Social Welfare «Sedankinsky nursing house for the disabled and aged people» of Vladivostok, from 6 to 12 months...
2017: Advances in Gerontology, Uspekhi Gerontologii
I L Bolshevidceva, A N Nekhoroshkova, I S Deputat
The article presents the results of studies of the direct current (DC) potential of the brain level distribution in elderly women with high anxiety. Analysis of the DC-potential of the brain level distribution was held by mapping obtained by measuring the monopolar values of the DC-potential of the brain and calculating deviations in each of the leads from the average records which were registrated in all areas of the head. The results of the study indicate an increase in the background level of the DC-potential in most parts of the brain and the peculiarity of its distribution in elderly women with a high level of anxiety...
2017: Advances in Gerontology, Uspekhi Gerontologii
V V Petrov, D L Tepliy
Nasal cavity - «the primary line of defense» and a major division of the respiratory tract. A variety of functional areas and regions, structural formations of the nasal cavity allows, at the present stage of development of biology and medicine, consider it as a complex functional subsystem in the structure of the respiratory system. The age transformations of morphological and functional parameters of the nasal cavity are polymorphic and specific. An important aspect of developmental physiology of the respiratory system is a study of the relationship of these changes with morphological and functional transformations of other systems of the body...
2017: Advances in Gerontology, Uspekhi Gerontologii
V V Petrov, D L Tepliy
The state of protective functions of the nasal cavity determines its homeostasis. At the stages of postnatal development and involution of functional parameters by endonasal homeostasis undergo a number of specific changes, the study of which has not only scientific value but also practical value for experimental physiology and clinical medicine. The article presents data on the age dynamics of functional indicators by endonasal homeostasis of human as buffer properties and morphological features of nasal secret...
2017: Advances in Gerontology, Uspekhi Gerontologii
V Yu Murylyov, P M Elizarov, Ya A Rukin, G G Rubin, G A Kukovenko
Hip arthroplasty outcomes for «difficult» eldery group of patient, aged 75-89 years, with femoral neck pseudarthrosis were analyzed. All patients were divided into 3 groups depending on the type of treatment (surgical or conservative) and terms of the removal of previously implanted metal constructions (before or during surgical procedure). Good and satisfactory results by Harris hip score were achieved in 94,8% of observations. The reasons of postoperative complications were considered for every group of patients...
2017: Advances in Gerontology, Uspekhi Gerontologii
G V Diachkova, N M Klyushin, K A Diachkov, T A Larionova
Radiography and multi-slice computed tomography (MSCT) were used to examine 30 patients with chronic osteomyelitis of lower limb whose age was over 60 years. There were more male patients with posttraumatic osteomyelitis of tibia. 16 patients were treated for chronic osteomyelitis for more than 5 years and 9 patients for more than 15 years. Control groups included 30 patients with chronic osteomyelitis of long bone aged 20 to 45 years and 30 patients aged 46 to 59 years. Radiographs of 19 patients of index group (63,3%) showed osteomyelitic cavities in the femur and tibia...
2017: Advances in Gerontology, Uspekhi Gerontologii
A A Garganeeva, O V Tukish, E A Kuzheleva
The paper presents the results of study 5-year survival of elderly patient after acute myocardial infarction. It is shown that this category of patients, used less invasive diagnostic and treatment strategy, compared with younger. In our study the effectiveness of primary percutaneous coronary intervention confirmed in patients with myocardial infarction with ST-segment elevation (STEMI) in relation to long-term survival. However, between the groups of successful thrombolytic therapy and pharmacoinvasive treatment strategy, no significant differences have been identified...
2017: Advances in Gerontology, Uspekhi Gerontologii
D Prudius, P Weber, H Matějovská Kubešová, H Meluzínová, V Polcarová, K Bieláková
The aim was to compare an occurrence of acute PE in hospitalized patients 65+ years old with diabetes mellitus (DM) with those without any DM. It was a retrospective analysis of data collected in documentation of patients who were hospitalized at the geriatric department in the years 2007-2015. In this period we had 11 947 patients of an average age of 79,9±8,5 years (min - 65, max - 103 years). Out of this number there were 4 069 diabetics. Acute PE was found in 344 patients of an average age 80,3±7,4 years...
2017: Advances in Gerontology, Uspekhi Gerontologii
N V Fridman, N S Linkova, V O Polyakova, A O Drobintseva, S V Тrofimova, I M Kvetnoy, V Kh Khavinson
Skin aging is one of the topical issues in modern gerontocosmetology. Application of cosmetic products with short peptides is a promising measure for retardation of skin aging. This research is aimed at investigation of KE (Lys-Glu, Vilon) dipeptide influence on the expression of markers of aging in human skin fibroblasts in vitro. Collagen type I and sirtuin-6 expression in «young» and «old» skin cell fibroblasts cultures was studied using immunofluorescence confocal microscopy method. The areas of expression of collagen type I and sirtuin-6 are known to decrease in skin fibroblasts with aging by 3,5 and 3,6 times accordingly...
2017: Advances in Gerontology, Uspekhi Gerontologii
V N Dmitriev
In the Belgorod region for 16 years of observation (2000-2015) number of persons who are annually recognized as recurrently disabled due to cancer increased by 113,4 %. Their specific weight increased from 6,9 up to 24,2 % and its average annual rate is 11,3%±5,9 of total number of recurrently disabled persons. In 2015 cancer as a reason of recurrent disability was on the 2d ranking place after cardiovascular system diseases. Cohort of persons recognized as recurrently disabled due to cancer include mainly persons of average (46,4%±9,9) and pension (27,7%±19,7) age, persons with disability groups II and III (37,2%±4,3 and 50,8%±4,1 respectively)...
2017: Advances in Gerontology, Uspekhi Gerontologii
D V Dumachev, K I Prashchayeu, E A Shcherban, A N Poltoratskiy, L I Kuzina
The article represents the results of a comparative analysis of the geriatric status, the Charlson comorbidity index and the geriatric variant of the cumulative illness rating scale for geriatrics (CIRS-G) in patients of different age groups with breast cancer, considering the concomitant pathology (CHF). It was revealed that the age classification of the WHO is more valid in determining the somatic and geriatric status of women with breast cancer. Also the evaluation of the severity of geriatric syndromes is given...
2017: Advances in Gerontology, Uspekhi Gerontologii
E L Gagarinskyi, N L Vekshin
This paper shows that the aging and death of nematodes, accompanied by the ignition of a blue glow under fluorescent microscopy, are not directly linked to any lipofuscin (aging pigment), nor with the anthranilic acid (a product of degradation of tryptophan residues of proteins). The main contribution in the blue flash of the dying nematodes belongs to parasitic light, scattered on the cuticle and bodies of the worm. The main contribution in the blue region at spectrofluorometry of homogenates, obtained from nematodes, really gives anthranilic acid...
2017: Advances in Gerontology, Uspekhi Gerontologii
I B Sokolova, G A Ryzhak, V Kh Khavinson
We investigated the influence of vascular peptide bioregulator on microcirculation in the brain cortex of spontaneously hypertensive rats of different ages and figured out whether there is functional cumulation during two-time application of the drug «Slavinorm» by above-mentioned animals. It was shown that a single course treatment with vascular peptide bioregulator had increased the density of microvascular network of the pia mater in young animals ca. 1,2-fold and had not affected the perfusion and oxygen saturation of sensorimotor cortex...
2017: Advances in Gerontology, Uspekhi Gerontologii
V V Nickel, V P Efremova
The study of paravasal connective tissue of the stomach was carried out on the preparations of 80 men corpses of three age groups: the first period of adulthood (n=20), the elderly (n=30) and senile (n=30) ages. With the help of standard histological and histochemical methods, the features of the age-related variability of the fiber composition were established; the level of apoptosis and proliferation in fibroblasts has been investigated with the help of immunohistochemical methods. The regularities of the structural organization of the paravasal connective tissue of the stomach during the period of biological stability (the first period of adulthood), as well as its age transformations at the stages of postnatal ontogeny (in the older age groups), were revealed...
2017: Advances in Gerontology, Uspekhi Gerontologii
G S Baturina, L E Katkova, N G Kolosova, E I Solenov
Senescence-associated alterations in structure and function of cornea make it more sensitive to traumas and disease. Trauma of cornea leads to edema and vision impairment and only corneal transplantation remains the effective for vision correction. Role of aquaporins for cornea endothelium function, as well as age-related changes of their activity, are not entirely understood. Herein, we studied changes with age the water permeability (Pf) of the plasma membranes of the corneal endothelial cells and the level of expression in them of the mRNA genes of the water channels of the aquaporins AQP1 and AQP3 in Wistar and senescence-accelerated OXYS rats...
2017: Advances in Gerontology, Uspekhi Gerontologii
N N Golubtsova, N K Kornilova, A G Gunin
The aim of our work was to examine content of serine-arginine protein kinase 1 (SRPK1) in human dermis at different ages (from 20 weeks of pregnancy to 85 years old). SRPK1, proliferating cells nuclear antigen (PCNA ), endothelial marker CD31 were detected in sections of the skin by indirect immunohistochemistry. Results showed, that content of SRPK1 in dermal fibroblasts was increased form antenatal period to 20 years of life followed by a decrease until 61-85 years period. SRPK1 content in dermal blood vessels is slowly gradually increased from antenatal period to 61-85 age interval...
2017: Advances in Gerontology, Uspekhi Gerontologii
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