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Advances in Gerontology, Uspekhi Gerontologii

N O Zakharova, S V Bulgakova, S E Katorkin, M A Melnikov, E V Treneva, A V Nikolaeva
The effectiveness of the inclusion of sulodexide in the pharmacotherapy of complex treatment of patients (n=52) elderly and senile with a combination of chronic diseases of the veins complicated by refractory trophic ulcers of the lower extremities, and type 2 diabetes mellitus was studied. Patients were randomly randomized in the 1st (n=26) and the 2nd (n=26) groups, the statistical differences between them in age (t1-2=0,2, p1-2=0,833), sex (χ21-2=0,008, p1-2=0,991), nosology (χ21-2=0,004, р1-2=0,993); the anamnesis of chronic diseases of veins (t1-2=0,14, p1-2=0,893); duration of trophic ulcers (t1-2=0,21, p1-2=0,827); planimetric parameters of trophic ulcers (t1-2=0,18, p1-2=0,865) were not recorded...
2017: Advances in Gerontology, Uspekhi Gerontologii
A G Soloviev, A A Shutova, M V Zlokazovа, E G Ichitovkina
Retrospective analysis of the dynamics of formation and nosological structure of mental disorders among the pensioners of the Ministry of internal Affairs (MIA) with the retirement on superannuation of mental disorder impeding further passage of service. All respondents were divided into two groups according to the criterion of participation in hostilities. It is shown that the ex-combatants, pensioners of MIA in the clinic dominated by organic disorder associated with the consequences of closed traumatic brain injury mine blast etiology, despite the rendered medical aid, the formation of personality disorders that violate social functioning and lead to disability...
2017: Advances in Gerontology, Uspekhi Gerontologii
I A Beltceva, N M Zalutskaya, T A Karavaeva, N G Neznanov
Phenomenon of hospitalism in elderly patients with mental disorders is an extremely important clinical, social and economic problem. 155 patients of the gerontopsychiatric hospital were examined, 75 of them showed signs of hospitalism, and 80 made up a control group. A subgroup of patients with signs and short duration of the disease was isolated, the duration of treatment in the hospital of these patients was 133,5±42,24 days (in the corresponding control subgroup 72,11±37,11 days, p<0,05). This subgroup was characterized by greater impulsiveness as a personality trait and less adaptive coping strategies...
2017: Advances in Gerontology, Uspekhi Gerontologii
B V Sigua, V P Zemlyanoy, C V Petrov, G M Rutenburg, A A Kozobin, A M Danilov
We analyzed the results of treatment of 80 patients of elderly and senile age with strangulated inguinal hernias, which were divided into two groups. From 2011 to 2014 were treated 58 patients (group 2) - in the treatment of this group used the traditional approach without the use of endovideosurgical technologies. From 2015 to 2016, it treated 22 patients (group 1) in the treatment of this group used individual diagnostic and treatment tactics with the use of diagnostic laparoscopy and laparoscopic hernioplasty...
2017: Advances in Gerontology, Uspekhi Gerontologii
E S Ostapchuk, V S Myakotnykh, T A Borovkova
In a sample of 116 patients aged 23 to 82 years was conducted study of the state of the cognitive sphere in the final stage of the acute period of ischemic and hemorrhagic stroke. Signs of cognitive deficits were detected in 80 (70%) of them, often over the age of 60 years and against the background of ischemic stroke. But only 8,6% of the representatives of elderly and senile patients disorders of cognitive functions are first diagnosed on a background of stroke. The majority of elderly patients they mentioned earlier, and the stroke only caused further progression of cognitive deficit...
2017: Advances in Gerontology, Uspekhi Gerontologii
E V Savelyev, D A Fedoryaka, N A Seliverstova, T N Reznikova
The article presents the results of psychological defense mechanism research of elderly persons group having mild cognitive impairments (51 persons). The leading defense mechanisms in this group were «reactive entity» and «denial». Reliable correlation between capacity of short-term memory, the MMSE test and «substitution», attention rate and «regression», leading psychological defense and indicators of anxiety, fear, depression and aggression of the studied group are found. The found correlation between defense tension and psychological parameters disclose features of intra personal adaptation of elderly persons having mild cognitive impairments...
2017: Advances in Gerontology, Uspekhi Gerontologii
R Negaresh, R Ranjbar, A Habibi, M Mokhtarzade, A Fokin, M M Gharibvand
Aging process is associated with loss of muscle mass, strength and growth factors dysfunction. Resistance training is one of the effective methods to overcome a decline in muscle mass, strength and also can modulate the level of myostatin, follistatin and insulin-like growth factor-1 (IGF-1) factors. The purpose of this study was to investigate the effect of 8 week resistance training on different anabolic factors which influence muscle hypertrophy in elderly and young men. Fifteen elderly and sixteen young men volunteered and participated in a periodized 3-day per week progressive resistance training program for a total of 8 weeks...
2017: Advances in Gerontology, Uspekhi Gerontologii
N G Platitsyna, T V Bolotnova
Vitamin D deficiency is an important risk factor for a number of chronic non-infectious diseases. The results of the study showed a high prevalence of vitamin D deficiency in patients with cardiovascular and bronchial obstruction diseases. Patients with coronary artery disease in association with hypertension were diagnosed with a vitamin D deficiency in 60% of cases, a pronounced deficiency in 40%; in patients with arterial hypertension - a vitamin D deficiency in 80%, and a pronounced deficit - in 20%; in patients with chronic obstructive pulmonary disease - vitamin D deficiency in 33%, and a pronounced deficit - in 67%; in patients with bronchial asthma - vitamin D deficiency in 75%, a severe deficit in 25%, and a vitamin D deficiency in 25% of the subjects...
2017: Advances in Gerontology, Uspekhi Gerontologii
N N Ilyinskikh, E N Ilyinskikh, E Yu Udartsev
It was studied the frequency of cells with cytogenetic abnormalities in the synovial fluid cells of the knee joint in patients of different age groups suffering from chronic arthritis associated with Lyme borreliosis (CAALB) or post-traumatic arthritis (PTA), depending on the polymorphism of the GSTM1 gene of glutathione-S-transferase. The study included 135 residents of the north of the Tomsk and Tyumen regions, 68 of whom suffered from CAALB, and the rest of the 67 patients who made up the control group were diagnosed with PTA...
2017: Advances in Gerontology, Uspekhi Gerontologii
V V Kostenko, N V Kolot
It was analyzed a comparative study of age-dependent changes in the parameters of reproductive function and embryonic development of offspring from adults w1c-s, w1Or mutant strains and Canton-S, Oregon-R wild-type strains D. melanogaster. In investigation three age groups of adult drosophila: 3, 10 and 20-days old were used. Reciprocal crosses between young and aging parents enable to define the influence of age of the maternal and/or paternal organism on the parameters of reproductive function. It is shown that the various features of reproductive function in F1 offspring of mutants and wild-type strains are forming differently by the different influence of the age of parents...
2017: Advances in Gerontology, Uspekhi Gerontologii
K V Derkach, V M Bondareva, A O Shpakov
The C-peptide, the product of proinsulin proteolysis, not only is a signal molecule, but also, forming a complex with insulin, is able to modulate the signaling functions of insulin. The signaling systems sensitive to insulin in the hypothalamus and other brain areas are among the targets of insulin. We hypothesized that in systemic deficiency of insulin and C-peptide in the type 1 diabetes mellitus (DM) and in severe forms of the type 2 DM, the increase in the level of C-peptide in the CNS will improve central effects of insulin, including its influence on peripheral metabolism...
2017: Advances in Gerontology, Uspekhi Gerontologii
V S Myakotnykh
No abstract text is available yet for this article.
2017: Advances in Gerontology, Uspekhi Gerontologii
A G Golubev
No abstract text is available yet for this article.
2017: Advances in Gerontology, Uspekhi Gerontologii
A A Moskalev
No abstract text is available yet for this article.
2017: Advances in Gerontology, Uspekhi Gerontologii
L A Gavrilov, N S Gavrilova
No abstract text is available yet for this article.
2017: Advances in Gerontology, Uspekhi Gerontologii
V M Novoselov
Recently, among gerontologists and the community, adjoining them for scientific interests, an acute discussion has arisen about the need to recognize the aging as a disease. The author discusses the philosophical, deontological, nosological, pathophysiological, clinical and biological aspects of this issue.
2017: Advances in Gerontology, Uspekhi Gerontologii
E K Papanova, V M Shkolnikov, E M Andreev, S A Timonin
Since the mid-2000s, after a few decades of negative trends and fluctuations, Russia has experienced the longest and most stable period of life expectancy increasing for the entire period of observation which was determined not only by a decrease in mortality at the middle ages, but also at the old ages. This period has been marked by a very fast increase in life expectancy of Muscovites. The paper shows that the mortality at old ages in Moscow systematically deviates from the patterns observed in economically developed countries with reliable mortality statistics...
2017: Advances in Gerontology, Uspekhi Gerontologii
V M Merabishvili
Malignant tumors have a particular specificity of the frequency of tumors in different age groups. The risk of cancer among people under 35 years of age is extremely low - 10-15 cases per 100 000 population of each age group. After 35 years of age with each age-related year the likelihood of cancer increases by 10% and for a five-year period by 50-70% reaching values of 2-5 thousand cases per 100 000 population in older groups. Knowing these patterns and details of localization structure for the each age it is possible to plan the implementation of a complex of anti-cancer measures correctly...
2017: Advances in Gerontology, Uspekhi Gerontologii
M A Paltsev, V A Zuev, E O Kozhevnikova, N S Linkova, T V Kvetnaia, V O Polyakova, I M Kvetnoy
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of elderly and old age people. For intravital diagnosis of the expression of signaling molecules - AD markers, cerebrospinal fluid (CSF) and peripheral tissues are used: lymphocytes and blood platelets, buccal and olfactory epithelium, skin fibroblasts. There are several changes in the production of hyper phosphorylated form of τ-protein, BACE1 and peptide Аβ42 in CSF in case of AD, but CSF taking may have a number of side effects. Less traumatic taking of sampling tissues for the diagnosis of AD is in use of epithelium biopsy and blood portion...
2017: Advances in Gerontology, Uspekhi Gerontologii
V B Voitenkov, E V Ekusheva, V N Komancev, N V Skripchenko, S G Grigoryev, A V Klimkin, A I Aksenova
Our aim was to present and evaluate age-related changes of peripheral nerves of limbs on a huge population of healthy subjects of different ages. In 2009-2016 subjects aged from 1months to 90 years were studied by nerve conduction velocity studies (NCV). Data of those confirmed healthy was included in our study. In total there were 372 healthy subjects. NCV for nn. Medianus et Ulnaris was registered, with NCV and amplitude of compound sensory action potential (CSAP) being analyzed. There were significant differences on both these parameters between different age groups...
2017: Advances in Gerontology, Uspekhi Gerontologii
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