Salome Rudin, Lilian Kriemler, Tolga D Dittrich, Annaelle Zietz, Juliane Schweizer, Markus Arnold, Nils Peters, Filip Barinka, Simon Jung, Marcel Arnold, Urs Fischer, Katharina Rentsch, Mirjam Christ-Crain, Mira Katan, Gian Marco De Marchis
BACKGROUND: Lipoprotein (a) [Lp(a)] serum levels are highly genetically determined and promote atherogenesis. High Lp(a) levels are associated with increased cardiovascular morbidity. Serum Lp(a) levels have recently been associated with large artery atherosclerosis (LAA) stroke. We aimed to externally validate this association in an independent cohort. METHODS: This study stems from the prospective multicentre CoRisk study (CoPeptin for Risk Stratification in Acute Stroke patients [NCT00878813]), conducted at the University Hospital Bern, Switzerland, between 2009 and 2011, in which Lp(a) plasma levels were measured within the first 24 hours after stroke onset...
April 2, 2024: Swiss Medical Weekly