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Biochemistry and Molecular Biology Education

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https://www.readbyqxmd.com/read/28627731/cell-migration-analysis-a-low-cost-laboratory-experiment-for-cell-and-developmental-biology-courses-using-keratocytes-from-fish-scales
#1
Daniel Prieto, Gonzalo Aparicio, Jose R Sotelo-Silveira
Cell and developmental processes are complex, and profoundly dependent on spatial relationships that change over time. Innovative educational or teaching strategies are always needed to foster deep comprehension of these processes and their dynamic features. However, laboratory exercises in cell and developmental biology at the undergraduate level do not often take into account the time dimension. In this article, we provide a laboratory exercise focused in cell migration, aiming to stimulate thinking in time and space dimensions through a simplification of more complex processes occurring in cell or developmental biology...
June 19, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28621449/a-flexible-e-learning-resource-promoting-the-critical-reading-of-scientific-papers-for-science-undergraduates
#2
Julie Letchford, Hazel Corradi, Trevor Day
An important aim of undergraduate science education is to develop student skills in reading and evaluating research papers. We have designed, developed, and implemented an on-line interactive resource entitled "Evaluating Scientific Research literature" (ESRL) aimed at students from the first 2 years of the undergraduate program. In this article, we describe the resource, then use student data collected from questionnaire surveys to evaluate the resource within 2 years of its launch. Our results add to those reported previously and indicate that ESRL can enable students to start evaluating research articles when used during their undergraduate program...
June 16, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28581156/the-usability-of-wechat-as-a-mobile-and-interactive-medium-in-student-centered-medical-teaching
#3
Juan Wang, Furong Gao, Jiao Li, Jieping Zhang, Siguang Li, Guo-Tong Xu, Lei Xu, Jianjun Chen, Lixia Lu
Biochemistry and cellular biology courses for medical students at Tongji University include the assessment that provides students with feedback to enhance their learning, which is a type of formative assessment. However, frequent instant feedback and guidance for students is often absent or inconsistently included in the teaching process. WeChat, the most popular Chinese social media, was introduced in biochemistry and cellular biology course. A WeChat official account (OA) was set up as an instant interactive platform...
June 5, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28544448/using-pymol-to-explore-the-effects-of-ph-on-noncovalent-interactions-between-immunoglobulin-g-and-protein-a-a-guided-inquiry-biochemistry-activity
#4
Zahilyn D Roche Allred, Heeyoung Tai, Stacey Lowery Bretz, Richard C Page
Students' understandings of foundational concepts such as noncovalent interactions, pH and pKa are crucial for success in undergraduate biochemistry courses. We developed a guided-inquiry activity to aid students in making connections between noncovalent interactions and pH/pKa . Students explore these concepts by examining the primary and tertiary structures of immunoglobulin G (IgG) and Protein A. Students use PyMOL, an open source molecular visualization application, to (1) identify hydrogen bonds and salt bridges between and within the proteins at physiological pH and (2) apply their knowledge of pH/pKa to association rate constant data for these proteins at pH 4 and pH 11...
May 24, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28544484/neglected-issues-concerning-teaching-human-adrenal-steroidogenesis-in-popular-biochemistry-textbooks
#5
Zhiyong Han, Mark S Elliott
In the human body, the adrenal steroids collectively regulate a plethora of fundamental functions, including electrolyte and water balance, blood pressure, stress response, intermediary metabolism, inflammation, and immunity. Therefore, adrenal steroidogenesis is an important biochemistry topic for students to learn in order for them to understand health consequences caused by deficiencies of enzymes in the adrenal steroidogenic pathways. However, popular biochemistry textbooks contain insufficient information and may sometimes give students a misimpression about certain aspects of human adrenal steroidogenesis...
May 19, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28520272/a-focus-on-polarity-investigating-the-role-of-orientation-cues-in-mediating-student-performance-on-mrna-synthesis-tasks-in-an-introductory-cell-and-molecular-biology-course
#6
Jeffrey T Olimpo, Daniel A Quijas, Anita M Quintana
The central dogma has served as a foundational model for information flow, exchange, and storage in the biological sciences for several decades. Despite its continued importance, however, recent research suggests that novices in the domain possess several misconceptions regarding the aforementioned processes, including those pertaining specifically to the formation of messenger ribonucleic acid (mRNA) transcripts. In the present study, we sought to expand upon these observations through exploration of the influence of orientation cues on students' aptitude at synthesizing mRNAs from provided deoxyribonucleic acid (DNA) template strands...
May 18, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28440907/the-story-of-crispr
#7
Adrian J Rawle, Fiona E Rawle
No abstract text is available yet for this article.
April 25, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28440901/examining-student-heuristic-usage-in-a-hydrogen-bonding-assessment
#8
Kathryn Miller, Thomas Kim
This study investigates the role of representational competence in student responses to an assessment of hydrogen bonding. The assessment couples the use of a multiple-select item ("Choose all that apply") with an open-ended item to allow for an examination of students' cognitive processes as they relate to the assignment of hydrogen bonding within a structural representation. Response patterns from the multiple-select item implicate heuristic usage as a contributing factor to students' incorrect responses...
April 25, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28436090/using-augmented-reality-to-teach-and-learn-biochemistry
#9
Juan Carlos Vega Garzón, Marcio Luiz Magrini, Eduardo Galembeck
Understanding metabolism and metabolic pathways constitutes one of the central aims for students of biological sciences. Learning metabolic pathways should be focused on the understanding of general concepts and core principles. New technologies such Augmented Reality (AR) have shown potential to improve assimilation of biochemistry abstract concepts because students can manipulate 3D molecules in real time. Here we describe an application named Augmented Reality Metabolic Pathways (ARMET), which allowed students to visualize the 3D molecular structure of substrates and products, thus perceiving changes in each molecule...
April 23, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28425189/the-global-ethics-corner-foundations-beliefs-and-the-teaching-of-biomedical-and-scientific-ethics-around-the-world
#10
Henry Jakubowski, Jianping Xie, Arup Kumar Mitra, Ravindra Ghooi, Saman Hosseinkhani, Mohsen Alipour, Behnam Hajipour, George Obiero
The profound advances in the biomolecular sciences over the last decades have enabled similar advances in biomedicine. These advances have increasingly challenged our abilities to deploy them in an equitable and ethically acceptable manner. As such, it has become necessary and important to teach biomedical and scientific ethics to our students who will become the researchers, medical professionals, and global citizens of the future. As advances in the biosciences and medicine are made, developed, and used across the globe, our survival on an endangered planet requires global dialog and consensual action...
April 19, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28419715/a-survey-on-faculty-perspectives-on-the-transition-to-a-biochemistry-course-based-undergraduate-research-experience-laboratory
#11
Paul A Craig
It will always remain a goal of an undergraduate biochemistry laboratory course to engage students hands-on in a wide range of biochemistry laboratory experiences. In 2006, our research group initiated a project for in silico prediction of enzyme function based only on the 3D coordinates of the more than 3800 proteins "of unknown function" in the Protein Data Bank, many of which resulted from the Protein Structure Initiative. Students have used the ProMOL plugin to the PyMOL molecular graphics environment along with BLAST, Pfam, and Dali to predict protein functions...
April 16, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28414867/basic-education-mexican-teachers-knowledge-of-biotechnology-and-attitudes-about-the-consumption-of-genetically-modified-foods
#12
Zacarías Jiménez-Salas, Eduardo Campos-Góngora, Blanca E González-Martínez, Alexandra Tijerina-Sáenz, Angélica D Escamilla-Méndez, Erik Ramírez-López
Over the past few years, a new research field has emerged, focusing on the social-scientific criteria for the study of opinions toward genetically modified foods (GMFs), since these may be limiting factors for the success or failure of these products. Basic education is the first step in the Mexican education system, and teachers may wield an outsized influence on the attitudes and preferences of children, prospective future consumers of these products. To better understand the current state of knowledge of biotechnology issues and opinions toward the consumption of GMF of Mexican teachers, a questionnaire was distributed, and 362 Mexican teachers of basic education responded...
April 16, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28407453/stressing-escherichia-coli-to-educate-students-about-research-a-cure-to-investigate-multiple-levels-of-gene-regulation
#13
Janet McDonough, Lara K Goudsouzian, Agllai Papaj, Ashley R Maceli, Vanja Klepac-Ceraj, Celeste N Peterson
Course-based undergraduate research experiences (CUREs) have been shown to increase student retention and learning in the biological sciences. Most CURES cover only one aspect of gene regulation, such as transcriptional control. Here we present a new inquiry-based lab that engages understanding of gene expression from multiple perspectives. Students carry out a forward genetic screen to identify regulators of the stationary phase master regulator RpoS in the model organism Escherichia coli and then use a series of reporter fusions to determine if the regulation is at the level of transcription or the post-transcription level...
April 13, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28509370/use-of-mushroom-tyrosinase-to-introduce-michaelis-menten-enzyme-kinetics-to-biochemistry-students
#14
William H Flurkey, Jennifer K Inlow
An inexpensive enzyme kinetics laboratory exercise for undergraduate biochemistry students is described utilizing tyrosinase from white button mushrooms. The exercise can be completed in one or two three-hour lab sessions. The optimal amounts of enzyme, substrate (catechol), and inhibitor (kojic acid) are first determined, and then kinetic data is collected in the absence and presence of the inhibitor. A Microsoft Excel template is used to plot the data and to fit the Michaelis-Menten equation to the data to determine the kinetic parameters Vmax and Km ...
May 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28509368/shining-the-spotlight-on-education
#15
EDITORIAL
Joan J Guinovart
No abstract text is available yet for this article.
May 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28032413/variation-in-external-representations-as-part-of-the-classroom-lecture-an-investigation-of-virtual-cell-animations-in-introductory-photosynthesis-instruction
#16
RANDOMIZED CONTROLLED TRIAL
Eric E Goff, Katie M Reindl, Christina Johnson, Phillip McClean, Erika G Offerdahl, Noah L Schroeder, Alan R White
The use of external representations (ERs) to introduce concepts in undergraduate biology has become increasingly common. Two of the most prevalent are static images and dynamic animations. While previous studies comparing static images and dynamic animations have resulted in somewhat conflicting findings in regards to learning outcomes, the benefits of each have been shown individually. Using ERs developed by the Virtual Cell Animation project, we aim to further investigate student learning using different ERs as part of an introductory biology lecture...
May 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28032403/a-unique-large-scale-undergraduate-research-experience-in-molecular-systems-biology-for-non-mathematics-majors
#17
Ulrike Kappler, Susan L Rowland, Rhianna K Pedwell
Systems biology is frequently taught with an emphasis on mathematical modeling approaches. This focus effectively excludes most biology, biochemistry, and molecular biology students, who are not mathematics majors. The mathematical focus can also present a misleading picture of systems biology, which is a multi-disciplinary pursuit requiring collaboration between biochemists, bioinformaticians, and mathematicians. This article describes an authentic large-scale undergraduate research experience (ALURE) in systems biology that incorporates proteomics, bacterial genomics, and bioinformatics in the one exercise...
May 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/27925371/effective-visual-design-and-communication-practices-for-research-posters-exemplars-based-on-the-theory-and-practice-of-multimedia-learning-and-rhetoric
#18
Rhianna K Pedwell, James A Hardy, Susan L Rowland
Evidence shows that science graduates often do not have the communication skills they need to meet workplace standards and expectations. One common mode of science communication is the poster. In a review of the literature we show that poster design is historically problematic, and that the guidance provided to students as they create posters for assessment is frequently inconsistent. To address this inconsistency we provide some guiding design principles for posters that are grounded in communication theory and the fundamentals of rhetoric...
May 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/27910203/designing-easy-dna-extraction-teaching-creativity-through-laboratory-practice
#19
RANDOMIZED CONTROLLED TRIAL
Endang Susantini, Lisa Lisdiana, Isnawati, Aushia Tanzih Al Haq, Guntur Trimulyono
Subject material concerning Deoxyribose Nucleic Acid (DNA) structure in the format of creativity-driven laboratory practice offers meaningful learning experience to the students. Therefore, a laboratory practice in which utilizes simple procedures and easy-safe-affordable household materials should be promoted to students to develop their creativity. This study aimed to examine whether designing and conducting DNA extraction with household materials could foster students' creative thinking. We also described how this laboratory practice affected students' knowledge and views...
May 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/27910201/meal-insulin-cycle-a-visual-summary-of-the-biochemical-events-between-meals
#20
Stavros Kalogiannis
In the present article, a scheme that summarizes the biochemical events occurring in the human body after the consumption of a meal is proposed. The scheme illustrates the metabolic sequence as a series of counteracting components occupying opposite positions in a cycle, indicating their opposite actions or physiological states, such as meal versus energy consumption, increase versus decrease of blood glucose levels, and excretion of insulin versus excretion of glucagon. Furthermore, the cycle is complemented by a table indicating the acceleration or inhibition of selected metabolic pathways and actions...
May 2017: Biochemistry and Molecular Biology Education
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