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Biochemistry and Molecular Biology Education

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https://www.readbyqxmd.com/read/28440907/the-story-of-crispr
#1
Adrian J Rawle, Fiona E Rawle
No abstract text is available yet for this article.
April 25, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28440901/examining-student-heuristic-usage-in-a-hydrogen-bonding-assessment
#2
Kathryn Miller, Thomas Kim
This study investigates the role of representational competence in student responses to an assessment of hydrogen bonding. The assessment couples the use of a multiple-select item ("Choose all that apply") with an open-ended item to allow for an examination of students' cognitive processes as they relate to the assignment of hydrogen bonding within a structural representation. Response patterns from the multiple-select item implicate heuristic usage as a contributing factor to students' incorrect responses...
April 25, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28436090/using-augmented-reality-to-teach-and-learn-biochemistry
#3
Juan Carlos Vega Garzón, Marcio Luiz Magrini, Eduardo Galembeck
Understanding metabolism and metabolic pathways constitutes one of the central aims for students of biological sciences. Learning metabolic pathways should be focused on the understanding of general concepts and core principles. New technologies such Augmented Reality (AR) have shown potential to improve assimilation of biochemistry abstract concepts because students can manipulate 3D molecules in real time. Here we describe an application named Augmented Reality Metabolic Pathways (ARMET), which allowed students to visualize the 3D molecular structure of substrates and products, thus perceiving changes in each molecule...
April 23, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28425189/the-global-ethics-corner-foundations-beliefs-and-the-teaching-of-biomedical-and-scientific-ethics-around-the-world
#4
Henry Jakubowski, Jianping Xie, Arup Kumar Mitra, Ravindra Ghooi, Saman Hosseinkhani, Mohsen Alipour, Behnam Hajipour, George Obiero
The profound advances in the biomolecular sciences over the last decades have enabled similar advances in biomedicine. These advances have increasingly challenged our abilities to deploy them in an equitable and ethically acceptable manner. As such, it has become necessary and important to teach biomedical and scientific ethics to our students who will become the researchers, medical professionals, and global citizens of the future. As advances in the biosciences and medicine are made, developed, and used across the globe, our survival on an endangered planet requires global dialog and consensual action...
April 19, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28419715/a-survey-on-faculty-perspectives-on-the-transition-to-a-biochemistry-course-based-undergraduate-research-experience-laboratory
#5
Paul A Craig
It will always remain a goal of an undergraduate biochemistry laboratory course to engage students hands-on in a wide range of biochemistry laboratory experiences. In 2006, our research group initiated a project for in silico prediction of enzyme function based only on the 3D coordinates of the more than 3800 proteins "of unknown function" in the Protein Data Bank, many of which resulted from the Protein Structure Initiative. Students have used the ProMOL plugin to the PyMOL molecular graphics environment along with BLAST, Pfam, and Dali to predict protein functions...
April 16, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28414867/basic-education-mexican-teachers-knowledge-of-biotechnology-and-attitudes-about-the-consumption-of-genetically-modified-foods
#6
Zacarías Jiménez-Salas, Eduardo Campos-Góngora, Blanca E González-Martínez, Alexandra Tijerina-Sáenz, Angélica D Escamilla-Méndez, Erik Ramírez-López
Over the past few years, a new research field has emerged, focusing on the social-scientific criteria for the study of opinions toward genetically modified foods (GMFs), since these may be limiting factors for the success or failure of these products. Basic education is the first step in the Mexican education system, and teachers may wield an outsized influence on the attitudes and preferences of children, prospective future consumers of these products. To better understand the current state of knowledge of biotechnology issues and opinions toward the consumption of GMF of Mexican teachers, a questionnaire was distributed, and 362 Mexican teachers of basic education responded...
April 16, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28407453/stressing-escherichia-coli-to-educate-students-about-research-a-cure-to-investigate-multiple-levels-of-gene-regulation
#7
Janet McDonough, Lara K Goudsouzian, Agllai Papaj, Ashley R Maceli, Vanja Klepac-Ceraj, Celeste N Peterson
Course-based undergraduate research experiences (CUREs) have been shown to increase student retention and learning in the biological sciences. Most CURES cover only one aspect of gene regulation, such as transcriptional control. Here we present a new inquiry-based lab that engages understanding of gene expression from multiple perspectives. Students carry out a forward genetic screen to identify regulators of the stationary phase master regulator RpoS in the model organism Escherichia coli and then use a series of reporter fusions to determine if the regulation is at the level of transcription or the post-transcription level...
April 13, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28314074/better-understanding-of-homologous-recombination-through-a-12-week-laboratory-course-for-undergraduates-majoring-in-biotechnology
#8
Ming Li, Xiaodong Shen, Yan Zhao, Xiaomei Hu, Fuquan Hu, Xiancai Rao
Homologous recombination, a central concept in biology, is defined as the exchange of DNA strands between two similar or identical nucleotide sequences. Unfortunately, undergraduate students majoring in biotechnology often experience difficulties in understanding the molecular basis of homologous recombination. In this study, we developed and implemented a 12-week laboratory course for biotechnology undergraduates in which gene targeting in Streptococcus suis was used to facilitate their understanding of the basic concept and process of homologous recombination...
March 17, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28294503/exploring-protein-structure-and-dynamics-through-a-project-oriented-biochemistry-laboratory-module
#9
James M Lipchock, Patrick S Ginther, Bonnie B Douglas, Kelly E Bird, J Patrick Loria
Here, we present a 10-week project-oriented laboratory module designed to provide a course-based undergraduate research experience in biochemistry that emphasizes the importance of biomolecular structure and dynamics in enzyme function. This module explores the impact of mutagenesis on an important active site loop for a biomedically-relevant human enzyme, protein tyrosine phosphatase 1B (PTP1B). Over the course of the semester students guide their own mutant of PTP1B from conception to characterization in a cost-effective manner and gain exposure to fundamental techniques in biochemistry, including site-directed DNA mutagenesis, bacterial recombinant protein expression, affinity column purification, protein quantitation, SDS-PAGE, and enzyme kinetics...
March 13, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28251766/new-horizons-in-biochemistry-molecular-biology-education-an-iubmb-sponsored-conference-5-8-september-2017-weizmann-institute-of-science-israel
#10
EDITORIAL
Gül Güner Akdogan, Janet Macaulay, Phillip Ortiz, Anat Yarden
No abstract text is available yet for this article.
March 2, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28251763/a-13-week-research-based-biochemistry-laboratory-curriculum
#11
Scott T Lefurgy, Emily C Mundorff
Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with mutations designed by the students. Ideal enzymes for this curriculum are able to be structurally modeled, solubly expressed, and monitored for activity by UV/Vis spectroscopy, and an example curriculum for haloalkane dehalogenase is given...
March 2, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28230335/undergraduate-medical-academic-performance-is-improved-by-scientific-training
#12
Lili Zhang, Wei Zhang, Chong Wu, Zhongming Liu, Yunfei Cai, Xingguo Cao, Yushan He, Guoxiang Liu, Hongming Miao
The effect of scientific training on course learning in undergraduates is still controversial. In this study, we investigated the academic performance of undergraduate students with and without scientific training. The results show that scientific training improves students' test scores in general medical courses, such as biochemistry and molecular biology, cell biology, physiology, and even English. We classified scientific training into four levels. We found that literature reading could significantly improve students' test scores in general courses...
February 23, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28230314/approaches-to-enhance-the-teaching-quality-of-experimental-biochemistry-for-mbbs-students-in-tsmu-china
#13
Lijuan Yu, Shuying Yi, Jing Zhai, Zhaojin Wang
With the internationalization of medical education in China, the importance of international students' education in medical schools is also increasing. Except foreign students majoring in Chinese language, English Bachelor of Medicine, Bachelor of Surgery (MBSS) students are the largest group of international students. Based on problems in the teaching process for experimental biochemistry, we designed teaching models adapted to the background of international students and strengthened teachers' teaching ability at Taishan Medical University...
February 23, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28220642/does-relevancy-matter
#14
LETTER
Daniel J Klionsky
No abstract text is available yet for this article.
February 20, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28205321/an-investigative-graduate-laboratory-course-for-teaching-modern-dna-techniques
#15
Alexandre de Lencastre, A Thomas Torello, Lani C Keller
This graduate-level DNA methods laboratory course is designed to model a discovery-based research project and engages students in both traditional DNA analysis methods and modern recombinant DNA cloning techniques. In the first part of the course, students clone the Drosophila ortholog of a human disease gene of their choosing using Gateway(®) cloning. In the second part of the course, students examine the expression of their gene of interest in human cell lines by reverse transcription PCR and learn how to analyze data from quantitative reverse transcription PCR (qRT-PCR) experiments...
February 16, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28145107/a-comprehensive-experiment-for-molecular-biology-determination-of-single-nucleotide-polymorphism-in-human-rev3-gene-using-pcr-rflp
#16
Xu Zhang, Meng Shao, Lu Gao, Yuanyuan Zhao, Zixuan Sun, Liping Zhou, Yongmin Yan, Qixiang Shao, Wenrong Xu, Hui Qian
Laboratory exercise is helpful for medical students to understand the basic principles of molecular biology and to learn about the practical applications of molecular biology. We have designed a lab course on molecular biology about the determination of single nucleotide polymorphism (SNP) in human REV3 gene, the product of which is a subunit of DNA polymerase ζ and SNPs in this gene are associated with altered susceptibility to cancer. This newly designed experiment is composed of three parts, including genomic DNA extraction, gene amplification by PCR, and genotyping by RFLP...
February 1, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28145077/using-molecular-visualization-to-explore-protein-structure-and-function-and-enhance-student-facility-with-computational-tools
#17
Cassidy R Terrell, Laura L Listenberger
Recognizing that undergraduate students can benefit from analysis of 3D protein structure and function, we have developed a multiweek, inquiry-based molecular visualization project for Biochemistry I students. This project uses a virtual model of cyclooxygenase-1 (COX-1) to guide students through multiple levels of protein structure analysis. The first assignment explores primary structure by generating and examining a protein sequence alignment. Subsequent assignments introduce 3D visualization software to explore secondary, tertiary, and quaternary structure...
February 1, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28145074/assessment-of-knowledge-of-participants-on-basic-molecular-biology-techniques-after-5-day-intensive-molecular-biology-training-workshops-in-nigeria
#18
J I Yisau, A O Adagbada, T Bamidele, M Fowora, B I C Brai, O Adebesin, M Bamidele, T Fesobi, F O Nwaokorie, A Ajayi, S I Smith
The deployment of molecular biology techniques for diagnosis and research in Nigeria is faced with a number of challenges, including the cost of equipment and reagents coupled with the dearth of personnel skilled in the procedures and handling of equipment. Short molecular biology training workshops were conducted at the Nigerian Institute of Medical Research (NIMR), to improve the knowledge and skills of laboratory personnel and academics in health, research, and educational facilities. Five-day molecular biology workshops were conducted annually between 2011 and 2014, with participants drawn from health, research facilities, and the academia...
February 1, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28059472/promoting-active-learning-of-graduate-student-by-deep-reading-in-biochemistry-and-microbiology-pharmacy-curriculum
#19
Ren Peng
To promote graduate students' active learning, deep reading of high quality papers was done by graduate students enrolled in biochemistry and microbiology pharmacy curriculum offered by college of life science, Jiangxi Normal University from 2013 to 2015. The number of graduate students, who participated in the course in 2013, 2014, and 2015 were eleven, thirteen and fifteen, respectively. Through deep reading of papers, presentation, and group discussion in the lecture, these graduate students have improved their academic performances effectively, such as literature search, PPT document production, presentation management, specialty document reading, academic inquiry, and analytical and comprehensive ability...
January 6, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28101912/meetings-calendar
#20
(no author information available yet)
No abstract text is available yet for this article.
January 2, 2017: Biochemistry and Molecular Biology Education
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