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BMC Urology

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https://www.readbyqxmd.com/read/29310636/sociodemographic-correlates-of-urine-culture-test-utilization-in-calgary-alberta
#1
Thomas P Griener, Christopher Naugler, Wilson W Chan, Deirdre L Church
BACKGROUND: Many clinical practice guidelines encourage diagnosis and empiric treatment of lower urinary tract infection without laboratory investigation; however, urine culture testing remains one of the largest volume tests in the clinical microbiology laboratory. In this study, we sought to determine if there were specific patient groups to which increased testing was directed. To do so, we combined laboratory data on testing rates with Census Canada sociodemographic data. METHODS: Urine culture testing data was obtained from the Calgary Laboratory Services information system for 2011...
January 8, 2018: BMC Urology
https://www.readbyqxmd.com/read/29310634/artificial-urinary-sphincter-implantation-an-important-component-of-complex-surgery-for-urinary-tract-reconstruction-in-patients-with-refractory-urinary-incontinence
#2
Fan Zhang, Limin Liao
BACKGROUND: We review our outcomes and experience of artificial urinary sphincter implantation for patients with refractory urinary incontinence from different causes. METHODS: Between April 2002 and May 2017, a total of 32 patients (median age, 40.8 years) with urinary incontinence had undergone artificial urinary sphincter placement during urinary tract reconstruction. Eighteen patients (56.3%) were urethral injuries associated urinary incontinence, 9 (28.1%) had neurogenic urinary incontinence and 5 (15...
January 8, 2018: BMC Urology
https://www.readbyqxmd.com/read/29304797/suprapubic-tube-versus-urethral-catheter-drainage-after-robot-assisted-radical-prostatectomy-a-systematic-review-and-meta-analysis
#3
Zhongyu Jian, Shijian Feng, Yuntian Chen, Xin Wei, Deyi Luo, Hong Li, Kunjie Wang
BACKGROUND: Prostate cancer is one of the most common cancers in the elderly population. The standard treatment is radical prostatectomy (RARP). However, urologists do not have consents on the postoperative urine drainage management (suprapubic tube (ST)/ urethral catheter (UC)). Thus, we try to compare ST drainage to UC drainage after robot-assisted radical prostatectomy regarding to comfort, recovery rate and continence using the method of meta-analysis. METHODS: A systematic search was performed in Dec...
January 5, 2018: BMC Urology
https://www.readbyqxmd.com/read/29284441/expression-of-cannabinoid-1-and-2-receptors-and-the-effects-of-cannabinoid-1-and-2-receptor-agonists-on-detrusor-overactivity-associated-with-bladder-outlet-obstruction-in-rats
#4
Sung Dae Kim, Kang Jun Cho, Joon Chul Kim
BACKGROUND: This study investigated changes in the expression of cannabinoid (CB) receptors and the effects of CB1 and CB2 agonists on detrusor overactivity (DO) associated with bladder outlet obstruction (BOO) in rats. METHODS: Male Sprague Dawley rats were randomly assigned to four groups (n = 10) in each group. The control group comprised sham-operated rats. A animals in the BOO, CB1 agonist and CB2 agonist groups all underwent BOO surgery. Three weeks postoperatively, cystometrography (CMG) was performed on all rats...
December 29, 2017: BMC Urology
https://www.readbyqxmd.com/read/29258481/cone-beam-ct-findings-during-prostate-artery-embolization-for-benign-prostatic-hyperplasia-induced-lower-urinary-tract-symptoms-a-case-report
#5
Chia-Bang Chen, Chen-Te Chou, Yao-Li Chen
No abstract text is available yet for this article.
December 19, 2017: BMC Urology
https://www.readbyqxmd.com/read/29246146/combined-bladder-neck-preservation-and-posterior-musculofascial-reconstruction-during-robotic-assisted-radical-prostatectomy-effects-on-early-and-long-term-urinary-continence-recovery
#6
Riccardo Bartoletti, Andrea Mogorovich, Francesco Francesca, Giorgio Pomara, Cesare Selli
BACKGROUND: To evaluate the effects of combined bladder neck preservation and posterior reconstruction techniques on early and long term urinary continence in patients treated by robotic assisted radical prostatectomy (RARP). METHODS: Two-hundred ninety-two patients who previously underwent radical prostatectomy were retrospectively selected for a case-control study, excluding those with anastomotic strictures and significant perioperative complications and re-called for a medical follow-up visit after their consent to participate the study...
December 15, 2017: BMC Urology
https://www.readbyqxmd.com/read/29233150/a-prospective-study-of-magnetic-resonance-imaging-and-ultrasonography-mri-us-fusion-targeted-biopsy-and-concurrent-systematic-transperineal-biopsy-with-the-average-of-18-cores-to-detect-clinically-significant-prostate-cancer
#7
Yuji Hakozaki, Hisashi Matsushima, Jimpei Kumagai, Taro Murata, Tomoko Masuda, Yoko Hirai, Mai Oda, Nobuo Kawauchi, Munehiro Yokoyama, Yukio Homma
BACKGROUND: This study compared the detection rates for clinically significant prostate cancer (CSPC) between magnetic resonance imaging and ultrasonography (MRI/US)-fusion-targeted biopsy (TB), systematic biopsy (SB) and combination of TB and SB. METHODS: This prospective study evaluated simultaneous TB and SB for consecutive patients with suspicious lesions that were detected using pre-biopsy multiparametric MRI. A commercially available real-time virtual sonography system was used to perform the MRI/US-fusion TB with the transperineal technique...
December 12, 2017: BMC Urology
https://www.readbyqxmd.com/read/29233144/evaluation-of-serum-prolidase-activity-and-oxidative-stress-markers-in-men-with-bph-and-prostate-cancer
#8
Faruk Kucukdurmaz, Erkan Efe, Ahmet Çelik, Hasan Dagli, Metin Kılınc, Sefa Resim
BACKGROUND: Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are diseases of elderly men and are related to increased oxidative stress (OS). Although prolidase has a role in collagen metabolism, it is also used to evaluate OS in many diseases. However, there is a lack of data about serum prolidase activity (SPA) in prostate cancer. The aim of this study was to evaluate and compare SPA levels in males with BPH and PCa. METHODS: Evaluation was made of a total of 81 men who underwent transrectal ultrasound guided prostate biopsy for a definitive diagnosis due to high PSA levels...
December 12, 2017: BMC Urology
https://www.readbyqxmd.com/read/29233118/risks-and-complications-of-transurethral-resection-of-bladder-tumors-in-patients-receiving-antiplatelet-and-or-anticoagulant-therapy-a-retrospective-cohort-study
#9
Tsuzumi Konishi, Satoshi Washino, Yuhki Nakamura, Masashi Ohshima, Kimitoshi Saito, Yoshiaki Arai, Tomoaki Miyagawa
BACKGROUND: Information on the safety of transurethral resection of bladder tumors (TURBT) in patients receiving anti-thromboembolic drugs is currently lacking. This study aimed to evaluate the clinical safety of TURBT in patients receiving anti-thromboembolic agents compared with patients not taking these agents and patients who interrupted their use perioperatively. METHODS: We retrospectively analyzed data for patients who underwent TURBT at Jichi Medical University Saitama Medical Center from September 2013 to August 2016...
December 12, 2017: BMC Urology
https://www.readbyqxmd.com/read/29221474/increased-expression-of-neuregulin-1-in-the-urothelium-of-rat-bladder-with-partial-bladder-outlet-obstruction
#10
Seung Woo Yang, Seong Woo Jeong, Ki Hak Song
BACKGROUND: This study determined whether changes in the expression of neuregulin (NRG) 1, erbB2 tyrosine kinase (ErbB2) and the M2 muscarinic receptor in the urothelium and detrusor muscle of the rat bladder were associated with partial bladder outlet obstruction (PBOO). METHODS: Male Sprague-Dawley rats (body weight 250-300 g) were used and subdivided into control (n = 10) and PBOO groups (n = 20). PBOO was induced for 21 days, and the expression of NRG1, ErbB2 and M2 muscarinic receptor mRNA and protein was evaluated using reverse transcriptase-polymerase chain reaction (RT-PCR) and western blotting, respectively...
December 8, 2017: BMC Urology
https://www.readbyqxmd.com/read/29212486/emerging-concepts-and-spectrum-of-renal-injury-following-intravesical-bcg-for-non-muscle-invasive-bladder-cancer
#11
Azharuddin Mohammed, Zubair Arastu
BACKGROUND: Intravesical Bacilli Calmette-Guerin (IVBCG) therapy for non-muscle invasive bladder cancer (NMIBC) has long been in use successfully. Albeit rarely, we still face with its safety concerns more than 25 years on since its approval by US Food and Drug Agency in 1990. Local and systemic infection following intravesical BCG is widely reported as compared to immune mediated local or systemic hypersensitivity reactions involving kidneys; acute kidney injury (AKI) and other renal manifestations are well reported but not of chronic kidney disease (CKD)...
December 6, 2017: BMC Urology
https://www.readbyqxmd.com/read/29202733/expression-of-micro-rnas-and-genes-related-to-angiogenesis-in-ccrcc-and-associations-with-tumor-characteristics
#12
Rita de Cássia Oliveira, Renato Fidelis Ivanovic, Katia Ramos Moreira Leite, Nayara Izabel Viana, Ruan César Aparecido Pimenta, José Pontes Junior, Vanessa Ribeiro Guimarães, Denis Reis Morais, Daniel Kanda Abe, Adriano João Nesrallah, Miguel Srougi, William Nahas, Sabrina Thalita Reis
BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer in adults. Our aim is to evaluate genes and miRNAs expression profiles involved with angiogenesis and tumor characteristics in ccRCC. METHODS: The expression levels of miRNAs miR-99a, 99b, 100; 199a; 106a; 106b; 29a; 29b; 29c; 126; 200a, 200b and their respective target genes: mTOR, HIF1-α, VHL, PDGF, VEGF, VEGFR1 and VEGFR2 were analyzed using qRT-PCR in tumor tissue samples from 56 patients with ccRCC...
December 4, 2017: BMC Urology
https://www.readbyqxmd.com/read/29197384/involvement-of-the-bone-morphogenic-protein-smad-signaling-pathway-in-the-etiology-of-congenital-anomalies-of-the-kidney-and-urinary-tract-accompanied-by-cryptorchidism
#13
Kentaro Mizuno, Akihiro Nakane, Hidenori Nishio, Yoshinobu Moritoki, Hideyuki Kamisawa, Satoshi Kurokawa, Taiki Kato, Ryosuke Ando, Tetsuji Maruyama, Takahiro Yasui, Yutaro Hayashi
BACKGROUND: Congenital anomalies of the kidney and urinary tract (CAKUT), such as renal dysplasia, hydronephrosis, or vesicoureteral reflux, are the most common causes of end-stage renal disease. However, the genetic etiology of CAKUT remains unclear. In this study, we performed whole exome sequencing (WES) to elucidate the genetic etiology of symptomatic CAKUT and CAKUT accompanied by cryptorchidism. METHODS: Three patients with unilateral renal dysplasia accompanied by ipsilateral cryptorchidism were included in this analysis...
December 2, 2017: BMC Urology
https://www.readbyqxmd.com/read/29197360/psychometric-properties-of-the-expanded-prostate-cancer-index-composite-26-instrument-in-a-cohort-of-radical-prostatectomy-patients-theoretical-and-practical-examinations
#14
Karol Axcrona, Rasmus Nilsson, Bjørn Brennhovd, Øystein Sørebø, Sophie D Fosså, Alv A Dahl
BACKGROUND: Recently, the Expanded Prostate Cancer Index Composite 26-item version (EPIC-26) was recommended for the assessment of adverse effects after the treatment of prostate cancer without clear reasons. This decision encouraged us to review the questionnaire development from the UCLA Prostate Cancer Index (UCLA-PCI) to the EPIC-16 CP with a focus on psychometric properties. We also reviewed PubMed for papers concerning such properties of the EPIC-26 since 2012 (latest review in 2011)...
December 2, 2017: BMC Urology
https://www.readbyqxmd.com/read/29195499/adjuvant-chemotherapy-improves-survival-of-patients-with-high-risk-upper-urinary-tract-urothelial-carcinoma-a-propensity-score-matched-analysis
#15
Kazutoshi Fujita, Kei Taneishi, Teruo Inamoto, Yu Ishizuya, Shingo Takada, Masao Tsujihata, Go Tanigawa, Noriko Minato, Shigeaki Nakazawa, Tsuyoshi Takada, Toshichika Iwanishi, Motohide Uemura, Yasushi Okuno, Haruhito Azuma, Nonomura Norio
BACKGROUND: The purposes of this study were to determine whether adjuvant chemotherapy (AC) improved the prognosis of patients with high-risk upper urinary tract urothelial carcinoma (UTUC)and to identify the patients who benefited from AC. METHODS: Among a multi-center database of 1014 patients who underwent RNU for UTUC, 344 patients with ≥ pT3 or the presence of lymphovascular invasion (LVI) were included. Cancer-specific survival (CSS) estimates were calculated by the Kaplan-Meier method, and groups were compared by the log-rank test...
December 1, 2017: BMC Urology
https://www.readbyqxmd.com/read/29183349/a-drosophila-genetic-model-of-nephrolithiasis-transcriptional-changes-in-response-to-diet-induced-stone-formation
#16
Vera Y Chung, Benjamin W Turney
BACKGROUND: Urolithiasis is a significant healthcare issue but the pathophysiology of stone disease remains poorly understood. Drosophila Malpighian tubules were known to share similar physiological function to human renal tubules. We have used Drosophila as a genetic model to study the transcriptional response to stone formation secondary to dietary manipulation. METHODS: Wild-type male flies were raised on standard medium supplemented with lithogenic agents: control, sodium oxalate (NaOx) and ethylene glycol (EG)...
November 28, 2017: BMC Urology
https://www.readbyqxmd.com/read/29162085/association-of-lower-urinary-tract-symptoms-and-oab-severity-with-quality-of-life-and-mental-health-in-china-taiwan-and-south-korea-results-from-a-cross-sectional-population-based-study
#17
Kyu-Sung Lee, Tag Keun Yoo, Limin Liao, Jianye Wang, Yao-Chi Chuang, Shih-Ping Liu, Romeo Chu, Budiwan Sumarsono
BACKGROUND: Lower urinary tract symptoms (LUTS) and overactive bladder (OAB) symptoms have a substantial effect on quality of life (QoL). We report QoL and mental health results from a LUTS prevalence study in three Asian countries. METHODS: A cross-sectional, population-representative, internet-based study among individuals aged ≥40 years in China, Taiwan and South Korea. Instruments included: Overactive Bladder Symptom Score (OABSS); International Prostate Symptom Score (IPSS); other International Continence Society (ICS) symptom questions; health-related QoL 12-item short-form (HRQoL-SF12v2); Work Limitations Questionnaire (WLQ); Hospital Anxiety and Depression Scale (HADS)...
November 21, 2017: BMC Urology
https://www.readbyqxmd.com/read/29162070/the-r-i-r-s-scoring-system-an-innovative-scoring-system-for-predicting-stone-free-rate-following-retrograde-intrarenal-surgery
#18
Yinglong Xiao, Deng Li, Lei Chen, Yaoting Xu, Dingguo Zhang, Yi Shao, Jun Lu
BACKGROUND: To establish and internally validate an innovative R.I.R.S. scoring system that allows urologists to preoperatively estimate the stone-free rate (SFR) after retrograde intrarenal surgery (RIRS). METHODS: This study included 382 eligible samples from a total 573 patients who underwent RIRS from January 2014 to December 2016. Four reproducible factors in the R.I.R.S. scoring system, including renal stone density, inferior pole stone, renal infundibular length and stone burden, were measured based on preoperative computed tomography of urography to evaluate the possibility of stone clearance after RIRS...
November 21, 2017: BMC Urology
https://www.readbyqxmd.com/read/29162068/new-steps-of-robot-assisted-radical-prostatectomy-using-the-extraperitoneal-approach-a-propensity-score-matched-comparison-between-extraperitoneal-and-transperitoneal-approach-in-japanese-patients
#19
Satoshi Kurokawa, Yukihiro Umemoto, Kentaro Mizuno, Atsushi Okada, Akihiro Nakane, Hidenori Nishio, Shuzo Hamamoto, Ryosuke Ando, Noriyasu Kawai, Keiichi Tozawa, Yutaro Hayashi, Takahiro Yasui
BACKGROUND: Robot-assisted radical prostatectomy (RARP) is commonly performed using the transperitoneal (TP) approach with six trocars over an 8-cm distance in the steep Trendelenburg position. In this study, we investigated the feasibility and the benefit of using the extraperitoneal (EP) approach with six trocars over a 4-cm distance in a flat or 5° Trendelenburg position. We also introduced four new steps to the surgical procedure and compared the surgical results and complications between the EP and TP approach using propensity score matching...
November 21, 2017: BMC Urology
https://www.readbyqxmd.com/read/29162067/necrotizing-fasciitis-after-high-dose-rate-brachytherapy-and-external-beam-radiation-for-prostate-cancer-a-case-report
#20
Shimpei Yamashita, Yasuo Kohjimoto, Akinori Iba, Kazuro Kikkawa, Isao Hara
BACKGROUND: In recent years, the delayed side effects associated with radiotherapy for prostate cancer have drawn the interest of urologists. Although urosymphyseal fistula is one of these delayed side effects, this serious complication is rarely described in literature and is poorly recognized. CASE PRESENTATION: We report our experience in treating a 77-year-old male patient with necrotizing fasciitis after high-dose rate brachytherapy plus external beam radiation for prostate cancer...
November 21, 2017: BMC Urology
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