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BMC Urology

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https://www.readbyqxmd.com/read/28431538/a-prospective-and-randomized-comparison-of-rigid-ureteroscopic-to-flexible-cystoscopic-retrieval-of-ureteral-stents
#1
Dehui Lai, Meiling Chen, Shifang Zha, Shawpong Wan
BACKGROUND: Flexible cystoscopy has become an accepted alternative for stent retrieval. However, it is associated with higher cost. Some reports have described experiences of using rigid ureteroscope to retrieve ureteral stents. We compared rigid ureteroscopic to flexible cystoscopic retrieval of ureteral stents in a prospective and randomized clinical trial. METHODS: Three hundred patients treated with ureteral stents between July 2012 and July 2013 were accrued in this study...
April 21, 2017: BMC Urology
https://www.readbyqxmd.com/read/28431537/the-role-of-flower-pollen-extract-in-managing-patients-affected-by-chronic-prostatitis-chronic-pelvic-pain-syndrome-a-comprehensive-analysis-of-all-published-clinical-trials
#2
Tommaso Cai, Paolo Verze, Roberto La Rocca, Umberto Anceschi, Cosimo De Nunzio, Vincenzo Mirone
BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is still a challenge to manage for all physicians. We feel that a summary of the current literature and a systematic review to evaluate the therapeutic efficacy of flower pollen extract would be helpful for physicians who are considering a phytotherapeutic approach to treating patients with CP/CPPS. METHODS: A comprehensive search of the PubMed and Embase databases up to June 2016 was performed...
April 21, 2017: BMC Urology
https://www.readbyqxmd.com/read/28403849/real-life-persistence-rate-with-antimuscarinic-treatment-in-patients-with-idiopathic-or-neurogenic-overactive-bladder-a-prospective-cohort-study-with-solifenacin
#3
Marloes J Tijnagel, Jeroen R Scheepe, Bertil F M Blok
BACKGROUND: Several studies have shown that the antimuscarinic treatment of overactive bladder is characterized by low long-term persistence rates. We have investigated the persistence of solifenacin in real life by means of telephonic interviews in a prospective cohort. We included both patients with idiopathic overactive bladder as well as neurogenic overactive bladder. METHODS: From June 2009 until July 2012 patients with idiopathic or neurogenic overactive bladder who were newly prescribed solifenacin were included...
April 13, 2017: BMC Urology
https://www.readbyqxmd.com/read/28388898/urinary-incontinence-mental-health-and-loneliness-among-community-dwelling-older-adults-in-ireland
#4
Andrew Stickley, Ziggi Ivan Santini, Ai Koyanagi
BACKGROUND: Urinary incontinence (UI) is associated with worse health among older adults. Little is known however, about its relation with loneliness or the role of mental health in this association. This study examined these factors among older adults in Ireland. METHODS: Data were analyzed from 6903 community-dwelling adults aged ≥ 50 collected in the first wave of The Irish Longitudinal Study on Ageing (TILDA) in 2009-11. Information was obtained on the self-reported occurrence (yes/no) and severity (frequency/activity limitations) of UI in the past 12 months...
April 8, 2017: BMC Urology
https://www.readbyqxmd.com/read/28381270/a-rare-diaphragmatic-ureteral-herniation-case-report-endoscopic-and-open-reconstructive-management
#5
Frank C Lin, Jamie S Lin, Samuel Kim, Jonathan R Walker
BACKGROUND: Ureteral herniations are a rare occurrence, generally found incidentally on cross sectional imaging or during surgical intervention for unrelated processes. Several locations of ureteral herniations can occur including the inguinal, femoral, sciatic, obturator, and thoracic regions. While few reports of ureteral hernias are reported in the literature overall, the vast majority of those reported are inguinoscrotal herniations found during evaluation and treatment of inguinal hernias...
April 5, 2017: BMC Urology
https://www.readbyqxmd.com/read/28381267/transperineal-template-guided-saturation-biopsy-aimed-at-sampling-one-core-for-each-milliliter-of-prostate-volume-103-cases-requiring-repeat-prostate-biopsy
#6
Yasushi Nakai, Nobumichi Tanaka, Satoshi Anai, Makito Miyake, Shunta Hori, Yoshihiro Tatsumi, Yosuke Morizawa, Tomomi Fujii, Noboru Konishi, Kiyohide Fujimoto
BACKGROUND: We evaluated the cancer detection rate of prostate cancer using transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume for patients requiring repeated prostate biopsies. METHODS: In total, 103 consecutive patients with repeated prostate biopsies were enrolled in this retrospective study. The number of biopsy cores was defined by prostate volume. In principle, one biopsy core covered 1 mL of prostate volume...
April 5, 2017: BMC Urology
https://www.readbyqxmd.com/read/28381220/the-prostate-cancer-detection-rates-of-ceus-targeted-versus-mri-targeted-versus-systematic-trus-guided-biopsies-in-biopsy-na%C3%A3-ve-men-a-prospective-comparative-clinical-trial-using-the-same-patients
#7
A W Postema, M J V Scheltema, C K Mannaerts, R J G Van Sloun, T Idzenga, M Mischi, M R E Engelbrecht, J J M C H De la Rosette, H Wijkstra
BACKGROUND: The current standard for Prostate Cancer (PCa) detection in biopsy-naïve men consists of 10-12 systematic biopsies under ultrasound guidance. This approach leads to underdiagnosis and undergrading of significant PCa while insignificant PCa may be overdiagnosed. The recent developments in MRI and Contrast Enhanced Ultrasound (CEUS) imaging have sparked an increasing interest in PCa imaging with the ultimate goal of replacing these "blind" systematic biopsies with reliable imaging-based targeted biopsies...
April 5, 2017: BMC Urology
https://www.readbyqxmd.com/read/28376845/rare-adrenal-gland-incidentaloma-an-unusual-ewing-s-sarcoma-family-of-tumor-presentation-and-literature-review
#8
Hui Guo, Shuaiqi Chen, Shukun Liu, Kaixuan Wang, Erpeng Liu, Faping Li, Yuchuan Hou
BACKGROUND: Members of the Ewing's sarcoma family of tumor (ESFT) are malignant neoplasms and rarely observed in the adrenal gland. CASE PRESENTATION: We report an extremely exceptional case of ESFT rising from the adrenal gland in a 57-year-old Chinese man. The patient was hospitalized with abdominal swelling for 2 months. Computed tomography (CT) scan revealed a nearly-circular mass measuring about 8.1 × 10.6 cm in the right adrenal region. The patient underwent right adrenal resection...
April 4, 2017: BMC Urology
https://www.readbyqxmd.com/read/28376772/different-expression-of-b7-h3-in-the-caput-corpus-and-cauda-of-the-epididymis-in-mouse
#9
Kai Li, Xuedong Wei, Guangbo Zhang, Miao Li, Xuefeng Zhang, Chenhao Zhou, Jianquan Hou, Hexing Yuan
BACKGROUND: B7-H3, a member of the B7 family of the Ig superfamily of proteins, has been detected in the epididymis, which is a storage organ related to sperm maturation. However, the characteristics of its expression in different regions of the epididymis remain unknown. Our aim was to investigate the expression of B7-H3 in the caput, corpus, and cauda of the epididymis. METHODS: We extracted epididymis specimens from adult male C57BL/6 mice. The expression of B7-H3 was then measured with immunohistochemistry, enzyme-linked immunosorbent assay (ELISA) and western blotting...
April 4, 2017: BMC Urology
https://www.readbyqxmd.com/read/28376750/clinical-relevance-of-aortic-calcification-in-urolithiasis-patients
#10
Toshikazu Tanaka, Shingo Hatakeyama, Hayato Yamamoto, Takuma Narita, Itsuto Hamano, Teppei Matsumoto, Osamu Soma, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Ippei Takahashi, Shigeyuki Nakaji, Yuriko Terayama, Tomihisa Funyu, Chikara Ohyama
BACKGROUND: The aim of the present study is to investigate the clinical relevance of aortic calcification in urolithiasis patients. METHODS: Between January 2010 and September 2014, 1221 patients with urolithiasis were treated in Oyokyo Kidney Research Institute and Hirosaki University Hospital. Among these, 287 patients (Stone group) on whom adequate data were available were included in this retrospective study. We also selected 148 subjects with early stage (pT1N0M0) renal cell carcinoma from 607 renal cell carcinoma patients who underwent radical nephrectomy at Hirosaki University Hospital (Non-stone group) as control subjects...
April 4, 2017: BMC Urology
https://www.readbyqxmd.com/read/28376747/benign-prostatic-enlargement-can-be-influenced-by-metabolic-profile-results-of-a-multicenter-prospective-study
#11
Mauro Gacci, Arcangelo Sebastianelli, Matteo Salvi, Cosimo De Nunzio, Linda Vignozzi, Giovanni Corona, Tommaso Jaeger, Tommaso Chini, Giorgio Ivan Russo, Mario Maggi, Giuseppe Morgia, Andrea Tubaro, Marco Carini, Sergio Serni
BACKGROUND: In last years Metabolic Syndrome (MetS) has been closely associated to Benign Prostatic Enlargement (BPE) Aim of our study is to evaluate the effect of MetS and each single MetS parameter on prostate growth in men surgically treated for BPE. METHODS: Overall, 379 men were prospectively enrolled in two tertiary referral centers. Calculated prostate volume (PV) was measured with transrectal US defining the antero-posterior (AP), the cranio-caudal (CC) and the latero-lateral (LL) diameters through the ellipsoid formula, while raw PV was calculated by suprapubic US...
April 4, 2017: BMC Urology
https://www.readbyqxmd.com/read/28351396/evaluation-and-treatment-for-ovotesticular-disorder-of-sex-development-ot-dsd-experience-based-on-a-chinese-series
#12
Yu Mao, Shaoji Chen, Ru Wang, Xuejun Wang, Daorui Qin, Yunman Tang
BACKGROUND: The aim of this study is to review and present the clinical features and process of evaluation and treatment for OT-DSD in a single center in recent years in China. METHODS: Sixteen patients with OT-DSD during the past 4 years underwent the evaluation and treatment in a single center. The clinical characteristics and outcomes of surgery were analyzed. RESULTS: The surgical age ranged from 17 months to 66 months with a mean age of 20 months, and the mean follow-up was 30 months (4 months to 56 months)...
March 28, 2017: BMC Urology
https://www.readbyqxmd.com/read/28351390/erratum-to-patient-preferences-for-treatment-of-castration-resistant-prostate-cancer-in-japan-a-discrete-choice-experiment
#13
Hiroji Uemura, Nobuaki Matsubara, Go Kimura, Akito Yamaguchi, Dianne Athene Ledesma, Marco DiBonaventura, Ateesha F Mohamed, Enrique Basurto, Ian McKinnon, Ed Wang, Kristen Concialdi, Aya Narimatsu, Yasuko Aitoku
No abstract text is available yet for this article.
March 28, 2017: BMC Urology
https://www.readbyqxmd.com/read/28327121/bap1-and-pbrm1-in-metastatic-clear-cell-renal-cell-carcinoma-tumor-heterogeneity-and-concordance-with-paired-primary-tumor
#14
Jeanette E Eckel-Passow, Daniel J Serie, John C Cheville, Thai H Ho, Payal Kapur, James Brugarolas, R Houston Thompson, Bradley C Leibovich, Eugene D Kwon, Richard W Joseph, Alexander S Parker
BACKGROUND: BAP1 and PBRM1 are frequently mutated in primary clear cell renal cell carcinoma (ccRCC) tumors; however, the frequency and clinical relevance of these mutations in metastatic ccRCC tumors is unknown. Additionally, while intra-tumor heterogeneity has been shown to be common in primary ccRCC, little is known regarding heterogeneity in metastatic ccRCC tumors. MATERIALS AND METHODS: We analyzed BAP1 and PBRM1 loss of protein expression in patient-matched primary and metastatic tumors from 97 patients...
March 21, 2017: BMC Urology
https://www.readbyqxmd.com/read/28320379/mirnas-associated-with-prostate-cancer-risk-and-progression
#15
REVIEW
Hung N Luu, Hui-Yi Lin, Karina Dalsgaard Sørensen, Olorunseun O Ogunwobi, Nagi Kumar, Ganna Chornokur, Catherine Phelan, Dominique Jones, LaCreis Kidd, Jyotsna Batra, Kosj Yamoah, Anders Berglund, Robert J Rounbehler, Mihi Yang, Sang Haak Lee, Nahyeon Kang, Seung Joon Kim, Jong Y Park, Giuliano Di Pietro
Prostate cancer is the most common malignancy among men in the US. Though considerable improvement in the diagnosis of prostate cancer has been achieved in the past decade, predicting disease outcome remains a major clinical challenge. Recent expression profiling studies in prostate cancer suggest microRNAs (miRNAs) may serve as potential biomarkers for prostate cancer risk and disease progression. miRNAs comprise a large family of about 22-nucleotide-long non-protein coding RNAs, regulate gene expression post-transcriptionally and participate in the regulation of numerous cellular processes...
March 20, 2017: BMC Urology
https://www.readbyqxmd.com/read/28284198/multicystic-nephroma-masquerading-as-hydatid-cyst-a-diagnostic-challenge
#16
Abdelmoneim E M Kheir, Aziza M Elnaeema, Sara M A Gafer, Sawsan A Mohammed, Mustafa E Bahar
BACKGROUND: Multicystic nephroma is an uncommon, non-familial renal neoplasm that is usually benign. About 200 cases of this lesion have been described in the literature. CASE PRESENTATION: We report on a Sudanese child who presented at the age of two and a half years with an abdominal mass, clinical and radiological features favored the diagnosis of hydatid cyst which is endemic in this African tropical country, and the diagnosis of multicystic nephroma was only possible after histopathological examination...
March 11, 2017: BMC Urology
https://www.readbyqxmd.com/read/28283031/the-resonance%C3%A2-metallic-ureteric-stent-in-the-treatment-of-chronic-ureteric-obstruction-a-safety-and-efficacy-analysis-from-a-contemporary-clinical-series
#17
C Patel, D Loughran, R Jones, M Abdulmajed, I Shergill
BACKGROUND: We evaluate the efficacy and safety of metallic ureteric stenting using the Cook Resonance® stent in the treatment of chronic ureteric obstruction of benign and malignant aetiology. Published experience of using this stent in this context is limited. We add to the body of literature on this topic. METHODS: All patients who had a Resonance® metallic stent inserted between April 2009 and November 2014 in our institution were identified from a prospectively maintained stent-database...
March 10, 2017: BMC Urology
https://www.readbyqxmd.com/read/28245870/multi-tract-percutaneous-nephrolithotomy-combined-with-ems-lithotripsy-for-bilateral-complex-renal-stones-our-experience
#18
Taisheng Liang, Chenming Zhao, Gang Wu, Botao Tang, Xiangdong Luo, Shangguang Lu, Yu Dong, Huan Yang
BACKGROUND: The treatment of bilateral complex renal stones is a tough challenge for urologists. This study aimed to evaluate the efficiency and safety of bilateral ultrasonography-guided multi-tract percutaneous nephrolithotomy (PCNL) combined with EMS lithotripsy for the treatment of such cases. METHODS: Twenty-seven patients suffering from bilateral complex renal calculi underwent t bilateral multi-tract PCNL. The PCNL began with the establishment of percutaneous nephrostomy access, which was achieved under ultrasound guidance followed by stone fragment and removal by EMS lithotripsy...
February 28, 2017: BMC Urology
https://www.readbyqxmd.com/read/28193277/anti-tumor-effects-of-a-recombinant-anti-prostate-specific-membrane-antigen-immunotoxin-against-prostate-cancer-cells
#19
Ping Meng, Qing-Chuan Dong, Guang-Guo Tan, Wei-Hong Wen, He Wang, Geng Zhang, Yan-Zhu Wang, Yu-Ming Jing, Chen Wang, Wei-Jun Qin, Jian-Lin Yuan
BACKGROUND: To evaluate anti-prostate cancer effects of a chimeric tumor-targeted killer protein. METHODS: We established a novel fusion gene, immunocasp-3, composed of NH2-terminal leader sequence fused with an anti-prostate-specific membrane antigen (PSMA) antibody (J591), the furin cleavage sequences of diphtheria toxin (Fdt), and the reverse coding sequences of the large and small subunits of caspase-3 (revcaspase-3). The expressing level of the immunocasp-3 gene was evaluated by using the reverse transcription-PCR (RT-PCR) and western blot analysis...
February 13, 2017: BMC Urology
https://www.readbyqxmd.com/read/28166753/aortic-calcification-burden-predicts-deterioration-of-renal-function-after-radical-nephrectomy
#20
Ken Fukushi, Shingo Hatakeyama, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Osamu Soma, Teppei Matsumoto, Itsuto Hamano, Takuma Narita, Atsushi Imai, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Yuriko Terayama, Tomihisa Funyu, Chikara Ohyama
BACKGROUND: Radical nephrectomy for renal cell carcinoma (RCC) is a risk factor for the development of chronic kidney disease (CKD), and the possibility of postoperative deterioration of renal function must be considered before surgery. We investigated the contribution of the aortic calcification index (ACI) to the prediction of deterioration of renal function in patients undergoing radical nephrectomy. METHODS: Between January 1995 and December 2012, we performed 511 consecutive radical nephrectomies for patients with RCC...
February 6, 2017: BMC Urology
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