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BMC Musculoskeletal Disorders

Ibrahim M Moustafa, Aliaa A Diab, Fatma Hegazy, Deed E Harrison
BACKGROUND: There is a growing interest concerning the understanding of and rehabilitation of the sagittal configuration of the cervical spine as a clinical outcome. However, the literature on the topic specific to conservative treatment outcomes of patients with chronic myofascial cervical pain syndrome (CMCPS) has not adequately addressed the relationship between cervical sagittal alignment and improved pain, disability and range of motion. METHODS: A randomized controlled study with a 1-year follow-up...
November 12, 2018: BMC Musculoskeletal Disorders
Keshav Poonit, Xijie Zhou, Bin Zhao, Chao Sun, Chenglun Yao, Feng Zhang, Jingwei Zheng, Hede Yan
BACKGROUND: Elbow osteoarthritis (OA) is a common disabling condition because of pain and loss of motion. Open and arthroscopic debridement are the preferred treatment, however there is no consensus on which treatment modality is suited to which category of patient or stage of disease. The objective of this study was to narratively review the literature for a more comprehensive understanding of its treatment options and associated outcomes, trying to provide a better treatment plan. METHODS: The PubMed database, EMBASE, Cochrane Library, and Google Scholar were searched, using the keywords (elbow [title/abstract] and osteoarthritis [title/abstract] and (surgery or open or arthroscop* or debridement or ulnohumeral arthroplasty) including all possible studies with a set of inclusion and exclusion criteria...
November 10, 2018: BMC Musculoskeletal Disorders
Michela Corsi, Carolina Alvarez, Leigh F Callahan, Rebecca J Cleveland, Yvonne M Golightly, Joanne M Jordan, Amanda E Nelson, Jordan Renner, Allen Tsai, Kelli D Allen
BACKGROUND: Osteoarthritis (OA) is associated with worsening physical function and a high prevalence of comorbid health conditions. In particular, cardiovascular disease (CVD) risk is higher in individuals with OA than the general population. Limitations in physical function may be one pathway to the development of CVD among individuals with OA. This study evaluated associations of symptomatic knee OA (sxKOA), baseline physical function and worsening of function over time with self-reported incident CVD in a community-based cohort...
November 10, 2018: BMC Musculoskeletal Disorders
S P Boelch, A Jakuscheit, S Doerries, L Fraissler, M Hoberg, J Arnholdt, M Rudert
BACKGROUND: We hypothesized, that periprosthetic joint infection (PJI) accounts for the major proportion of first (primary) and repeated (secondary) Total Knee Arthroplasty revisions at our university referral arthroplasty center. METHODS: One thousand one hundred forty-three revisions, performed between 2008 and 2016 were grouped into primary (55%) and secondary (45%) revisions. The rate of revision indications was calculated and indications were categorized by time after index operation...
November 10, 2018: BMC Musculoskeletal Disorders
Shanthi Ramanathan, Peter Hibbert, Louise Wiles, Christopher G Maher, William Runciman
BACKGROUND: Although "non-specific" in 90% of cases, low back pain (LBP) is often treated as an independent entity, even though comorbidities are commonly associated with it. There is evidence that some LBP may be related to chronic conditions or be a symptom of poor health. The purpose of this study was to clarify the extent of comorbidities amongst a cohort of Australian adults with LBP and examine if having concurrent conditions has any association with appropriateness of care for LBP...
November 6, 2018: BMC Musculoskeletal Disorders
Thawee Songpatanasilp, Sattaya Rojanasthien, Pansak Sugkraroek, Boonsong Ongphiphadhanakul, Lamar Robert, Chongchit Sripun Robert, Sirichai Luevitoonvechkij, Arthur C Santora
BACKGROUND: It is generally believed that Thai people do not suffer from hypovitaminosis D because there is abundant sunlight throughout the year, and that taking vitamin D supplements could result in abnormally high levels of vitamin D. This is a Thai FDA-driven study to investigate this risk over a period of 26 weeks of taking alendronate sodium/vitamin D3 combination tablets. METHODS: Osteoporosis patients in Thailand were recruited to a multicenter, open-label, 6-month trial of oral alendronate sodium 70 mg/vitamin D3 5600 IU...
November 6, 2018: BMC Musculoskeletal Disorders
Katarina Aili, Maria Andersson, Ann Bremander, Emma Haglund, Ingrid Larsson, Stefan Bergman
BACKGROUND: Previous research suggests that sleep problems may be an important predictor for chronic widespread pain (CWP). With this study we investigated both sleep problems and fatigue as predictors for the onset of CWP over a 5-year and an 18-year perspective in a population free from CWP at baseline. METHODS: To get a more stable classification of CWP, we used a wash-out period, including only individuals who had not reported CWP at baseline (1998) and three years prior baseline (1995)...
November 3, 2018: BMC Musculoskeletal Disorders
Michael J Fischer, Gergo Horvath, Martin Krismer, Erich Gnaiger, Georg Goebel, Dominik H Pesta
BACKGROUND: Myofascial trigger points (MTrPs) are hyperirritable areas in the fascia of the affected muscle, possibly related to mitochondrial impairment. They can result in pain and hypoxic areas within the muscle. This pilot study established a minimally invasive biopsy technique to obtain high-quality MTrP tissue samples to evaluate mitochondrial function via high-resolution respirometry. Secondary objectives included the feasibility and safety of the biopsy procedure. METHODS: Twenty healthy males participated in this study, 10 with a diagnosis of myofascial pain in the musculus (m...
October 30, 2018: BMC Musculoskeletal Disorders
Catherine D Hughes, David L Scott, Fowzia Ibrahim
BACKGROUND: We systematically reviewed the effectiveness of intensive treatment strategies in achieving remission in patients with both early and established Rheumatoid Arthritis (RA). METHODS: A systematic literature review and meta-analysis evaluated trials and comparative studies reporting remission in RA patients treated intensively with disease modifying anti-rheumatic drugs (DMARDs), biologics and Janus Kinase (JAK) inhibitors. Analysis used RevMan 5.3 to report relative risks (RR) in random effects models with 95% confidence intervals (CI)...
October 30, 2018: BMC Musculoskeletal Disorders
Aqeeda Singh, Mario Scholze, Niels Hammer
BACKGROUND: Biomechanical testing using image-based deformation detection techniques such as digital image correlation (DIC) offer optical contactless methods for strain and displacement measurements of biological tissues. However, given the need of most samples to be speckled for image correlation using sprays, chemical alterations with impact on tissue mechanicals may result. The aim of this study was to assess the impact of such surface coating on the mechanical properties of rat bones, under routine laboratory conditions including multiple freeze-thaw cycles...
October 27, 2018: BMC Musculoskeletal Disorders
Elizabeth Lane, Julie M Fritz, Tom Greene, Daniel Maddox
BACKGROUND: Chronic spinal pain affects many in the United States and is associated with rising healthcare costs - but not improved outcomes. Education and self-care promotion are hallmarks of the recommended approach for this condition. Pain Neuroscience Education (PNE) is a method of educating patients about the neurophysiology of pain that aims to reconceptualize pain from an indicator of damage to an interpretation of input signals by the brain and nervous system. PNE has shown efficacy in controlled situations when delivered by experts, but its effectiveness has not been investigated among trained clinicians in a pragmatic setting...
October 25, 2018: BMC Musculoskeletal Disorders
Maliheh Ghaneei, Amin Komeili, Yong Li, Eric C Parent, Samer Adeeb
BACKGROUND: Three dimensional (3D) markerless asymmetry analysis was developed to assess and monitor the scoliotic curve. While the developed surface topography (ST) indices demonstrated a strong correlation with the Cobb angle and its change over time, it was reported that the method requires an expert for monitoring the procedure to prevent misclassification for some patients. Therefore, this study aimed at improving the user-independence level of the previously developed 3D markerless asymmetry analysis implementing a new asymmetry threshold without compromising its accuracy in identifying the progressive scoliotic curves...
October 24, 2018: BMC Musculoskeletal Disorders
Ian A Jones, Melissa Wilson, Ryan Togashi, Bo Han, Austin K Mircheff, C Thomas Vangsness
BACKGROUND: Osteoarthritis (OA) is a highly debilitating joint disease that causes progressive, irreversible damage to articular cartilage. OA takes a massive toll on society that has grown in recent decades, but no therapy has been shown to halt or reverse the progression of the disease. The critical need for better treatments and increased interest cellular therapies has spawned a new generation of "minimally manipulated" cell treatments. Autologous adipose tissue injections are among the most controversial of these new treatments...
October 24, 2018: BMC Musculoskeletal Disorders
Humaira Mahmood, Duncan E T Shepherd, Daniel M Espino
BACKGROUND: Changes in bone mineral density have been implicated with the onset of osteoarthritis, but its role in inducing failure of articular cartilage mechanically is unclear. This study aimed to determine the effect of substrate density, as the underlying bone, on the surface damage of cartilage-off-bone, at frequencies associated with gait, and above. METHODS: Bovine articular cartilage samples were tested off-bone to assess induced damage with an indenter under a compressive sinusoidal load range of 5-50 N at frequencies of 1, 10 and 50 Hz, corresponding to normal and above normal gait respectively, for up to 10,000 cycles...
October 24, 2018: BMC Musculoskeletal Disorders
JuHong Lee, SungIl Wang, KiBum Kim
BACKGROUND: The aim of this study is (1) to compare joint line (JL) restoration and clinical outcomes in revision TKA based on the contemporary prosthesis type and (2) to determine the restoration of posterior condylar offset (PCO) according to the use of a femoral offset stem. METHODS: Sixty knees that underwent revision TKA from April 2003 to December 2013 with a minimum of 1 year follow up were included. These were further subdivided into three groups according to prosthesis type: group I (2 mm offset), group II (4...
October 20, 2018: BMC Musculoskeletal Disorders
Hye-Young Shim, Mira Park, Hee-June Kim, Hee-Soo Kyung, Ji-Yeon Shin
BACKGROUNDS: Few reports have explored the extent to which physical activity is affected by pain severity in knee osteoarthritis (KOA) patients. We used national representative data to investigate the physical activity of KOA patients compared to the general population to determine what proportion of patients met physical activity recommendations and to explore how the proportion changes with pain severity. METHODS: We used data from the fifth Korean National Health and Nutrition Examination Survey (KNHANES V; 2010-2012)...
October 20, 2018: BMC Musculoskeletal Disorders
Donghua Huang, Xiangyu Deng, Kaige Ma, Fashuai Wu, Deyao Shi, Hang Liang, Sheng Chen, Zengwu Shao
BACKGROUND: Intervertebral disk degeneration (IDD) is a common musculoskeletal disease associated with genetic factors. COL9A3 gene encodes the α3 (IX) chain of type IX collagen that is part of the interior structure of the disc. Mutations in COL9A3 gene sequence, leading to an Arg103Trp substitution in its 3 chain (the Trp3 allele at rs61734651 site), respectively, have been found to be connected with IDD occurrence in several studies. However, those studies have showed conflict results...
October 20, 2018: BMC Musculoskeletal Disorders
Tomoya Ishida, Yuta Koshino, Masanori Yamanaka, Ryo Ueno, Shohei Taniguchi, Mina Samukawa, Hiroshi Saito, Hisashi Matsumoto, Yoshimitsu Aoki, Harukazu Tohyama
BACKGROUND: A double-leg landing with or without a subsequent jump is commonly used to evaluate the neuromuscular control of knee abduction. However, the differences in frontal plane knee biomechanics between landings with and without a subsequent jump are not well known. The purpose of the present study was to investigate the effects of a subsequent jump on knee abduction, including during the early landing phase, in female and male subjects. METHODS: Twenty-one female subjects and 21 male subjects participated...
October 20, 2018: BMC Musculoskeletal Disorders
Irazú Contreras-Yáñez, G Guaracha-Basáñez, E Díaz-Borjón, M Iglesias, V Pascual-Ramos
BACKGROUND: Reconstructive joint surgery is an indicator of poor prognosis in rheumatoid arthritis (RA). Objectives of this study were to describe the incidence rate of orthopedic and hand surgery indication (OHSI) in an ongoing cohort of Hispanic early RA patients treated according to a T2T strategy and to investigate predictors. METHODS: Through February 2018, the cohort comprised 185 patients recruited from 2004 onwards, with variable follow-up, and rheumatic assessments at fixed intervals that included prospective determination of OHSI...
October 20, 2018: BMC Musculoskeletal Disorders
Mauro A S Melloni, Josiel De Almeida Ávila, Mauro Alexandre Páscoa, Camila Justino De Oliveira Barbeta, Vagner Xavier Cirolini, Ezequiel M Gonçalves, Gil Guerra-Júnior
BACKGROUND: Musculoskeletal injuries are the main cause of premature discharge from military service and can sometimes lead to permanent disabilities. Some intrinsic risk factors are well discussed in the literature. However, the relation between body composition variables and the risk for musculoskeletal injury is not well known or recognized. METHODS: This prospective study evaluated 205 Brazilian military students. At the beginning of military service, health status and sports experience prior to military service were registered...
October 17, 2018: BMC Musculoskeletal Disorders
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