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BMC Psychiatry

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https://www.readbyqxmd.com/read/28629452/inhibitory-brainstem-reflexes-under-external-emotional-stimuli-in-bipolar-i-and-ii-disorders
#1
Qisha Zhu, Jiawei Wang, Chanchan Shen, Hongying Fan, Bingren Zhang, Guorong Ma, Yanxia Lu, Wei Wang
BACKGROUND: Bipolar disorder types I (BD I) and II (BD II) might present different dysfunctions of the cortex and brainstem, as reflected by the second exteroceptive suppression period of temporalis muscle activity (ES2) under different stimuli of external emotions. METHODS: This study included 30 BD I and 20 BD II patients, and 40 healthy volunteers. All participants were invited to answer the Mood Disorder Questionnaire, the Hypomania Checklist-32, and the Plutchik-van Praag Depression inventory, as well as to undergo the ES2 test under external emotional-stimuli (emotional pictures plus sounds) of Disgust, Erotica, Fear, Happiness, and Sadness...
June 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28629442/treatment-patterns-healthcare-resource-utilization-and-costs-following-first-line-antidepressant-treatment-in-major-depressive-disorder-a-retrospective-us-claims-database-analysis
#2
Geneviève Gauthier, Annie Guérin, Maryia Zhdanava, William Jacobson, George Nomikos, Elizabeth Merikle, Clément François, Vanessa Perez
BACKGROUND: Although the symptoms of major depressive disorder (MDD) are often manageable with pharmacotherapy, response to first-line antidepressant treatment is often less than optimal. This study describes long-term treatment patterns in MDD patients in the United States and quantifies the economic burden associated with different treatment patterns following first-line antidepressant therapy. METHODS: MDD patients starting first-line antidepressant monotherapy and having continuous enrollment ≥12 months before and ≥24 months following the index date (i...
June 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28619050/a-standardized-crisis-management-model-for-self-harming-and-suicidal-individuals-with-three-or-more-diagnostic-criteria-of-borderline-personality-disorder-the-brief-admission-sk%C3%A3-ne-randomized-controlled-trial-protocol-basrct
#3
Sophie I Liljedahl, Marjolein Helleman, Daiva Daukantaité, Åsa Westrin, Sofie Westling
BACKGROUND: Brief Admission is a crisis and risk management strategy in which self-harming and suicidal individuals with three or more diagnostic criteria of borderline personality disorder self-admit to hospital at times of increasing risk when other efforts to stay safe are failing. Standardized in the current randomized controlled trial, the intensity of Brief Admission Skåne is implemented in durations of three days, with a maximum frequency of three times a month. Brief Admission is integrated into existing treatment plans in advance of crises to prevent reliance on general psychiatric admissions for risk management, as these may be lengthy, unstructured, and of uncertain therapeutic value...
June 15, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28619017/borderline-personality-disorder-and-childhood-trauma-exploring-the-affected-biological-systems-and-mechanisms
#4
Nadia Cattane, Roberta Rossi, Mariangela Lanfredi, Annamaria Cattaneo
BACKGROUND: According to several studies, the onset of the Borderline Personality Disorder (BPD) depends on the combination between genetic and environmental factors (GxE), in particular between biological vulnerabilities and the exposure to traumatic experiences during childhood. We have searched for studies reporting possible alterations in several biological processes and brain morphological features in relation to childhood trauma experiences and to BPD. We have also looked for epigenetic mechanisms as they could be mediators of the effects of childhood trauma in BPD vulnerability...
June 15, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28610603/an-australian-indigenous-community-led-suicide-intervention-skills-training-program-community-consultation-findings
#5
Bushra Nasir, Steve Kisely, Leanne Hides, Geetha Ranmuthugala, Sharon Brennan-Olsen, Geoffrey C Nicholson, Neeraj S Gill, Noel Hayman, Srinivas Kondalsamy-Chennakesavan, Maree Toombs
BACKGROUND: Little is known of the appropriateness of existing gatekeeper suicide prevention programs for Indigenous communities. Despite the high rates of Indigenous suicide in Australia, especially among Indigenous youth, it is unclear how effective existing suicide prevention programs are in providing appropriate management of Indigenous people at risk of suicide. METHODS: In-depth, semi-structured interviews and focus groups were conducted with Indigenous communities in rural and regional areas of Southern Queensland...
June 13, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28610561/blended-care-vs-usual-care-in-the-treatment-of-depressive-symptoms-and-disorders-in-general-practice-blending-study-protocol-of-a-non-inferiority-randomized-trial
#6
Btissame Massoudi, Marco H Blanker, Evelien van Valen, Hans Wouters, Claudi L H Bockting, Huibert Burger
BACKGROUND: The majority of patients with depressive disorders are treated by general practitioners (GPs) and are prescribed antidepressant medication. Patients prefer psychological treatments but they are under-used, mainly due to time constraints and limited accessibility. A promising approach to deliver psychological treatment is blended care, i.e. guided online treatment. However, the cost-effectiveness of blended care formatted as an online psychological treatment supported by the patients' own GP or general practice mental health worker (MHW) in routine primary care is unknown...
June 13, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28606061/a-pilot-study-on-feasibility-acceptance-and-effectiveness-of-metacognitive-oriented-social-skills-training-in-schizophrenia
#7
Felix Inchausti, Nancy V García-Poveda, Alejandro Ballesteros-Prados, Eduardo Fonseca-Pedrero, Javier Ortuño-Sierra, Sergio Sánchez-Reales, Javier Prado-Abril, José Antonio Aldaz-Armendáriz, Joe Mole
BACKGROUND: In preparation for a randomized controlled trial, a pilot study was conducted to investigate the feasibility, acceptability and effectiveness of a psychotherapy group based on metacognitive-oriented social skills training (MOSST). METHODS: Twelve outpatients with schizophrenia were offered 16 group-sessions of MOSST. Effect sizes were calculated for changes from baseline to treatment end for both psychosocial functioning and metacognitive abilities measured by the Personal and Social Performance Scale (PSP) and the Metacognition Assessment Scale-Abbreviated (MAS-A) respectively...
June 12, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28599624/prevalence-and-factors-associated-with-depression-among-medical-students-in-cameroon-a-cross-sectional-study
#8
Stewart Ndutard Ngasa, Carlson-Babila Sama, Bonaventure Suiru Dzekem, Kilton Neba Nforchu, Maxime Tindong, Desmond Aroke, Christian Akem Dimala
BACKGROUND: Depression is an important contributor to the global burden disease that affects people of communities all over the world. With high level of demands in academics and psychosocial pressure, medical students during their course of training tend to become depressed, leading to problems later in professional life and compromising patient care. In Cameroon, there is lack of data on the prevalence of depression and its impact on medical students. To determine the prevalence and predisposing factors associated with depression among medical students in Cameroon (preclinical and clinical)...
June 9, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28599621/the-comparative-effectiveness-and-efficiency-of-cognitive-behaviour-therapy-and-generic-counselling-in-the-treatment-of-depression-evidence-from-the-2-nd-uk-national-audit-of-psychological-therapies
#9
Jo Pybis, David Saxon, Andy Hill, Michael Barkham
BACKGROUND: Cognitive Behaviour Therapy (CBT) is the front-line psychological intervention for step 3 within UK psychological therapy services. Counselling is recommended only when other interventions have failed and its effectiveness has been questioned. METHOD: A secondary data analysis was conducted of data collected from 33,243 patients across 103 Improving Access to Psychological Therapies (IAPT) services as part of the second round of the National Audit of Psychological Therapies (NAPT)...
June 9, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28587668/alterations-of-hair-cortisol-and-dehydroepiandrosterone-in-mother-infant-dyads-with-maternal-childhood-maltreatment
#10
K Schury, A M Koenig, D Isele, A L Hulbert, S Krause, M Umlauft, S Kolassa, U Ziegenhain, A Karabatsiakis, F Reister, H Guendel, J M Fegert, I-T Kolassa
BACKGROUND: Child maltreatment (CM) has severe effects on psychological and physical health. The hypothalamic-pituitary-adrenal (HPA) axis, the major stress system of the body, is dysregulated after CM. The analysis of cortisol and dehydroepiandrosterone (DHEA) in scalp hair presents a new and promising methodological approach to assess chronic HPA axis activity. This study investigated the effects of CM on HPA axis activity in the last trimester of pregnancy by measuring the two important signaling molecules, cortisol and DHEA in hair, shortly after parturition...
June 6, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28587610/trends-in-gp-prescribing-of-psychotropic-medications-among-young-patients-aged-16-24%C3%A2-years-a-case-study-analysis
#11
Bianca Brijnath, Ting Xia, Lyle Turner, Danielle Mazza
BACKGROUND: Current clinical guidelines recommend non-pharmacological interventions as first-line treatments for young patients aged 16-24 years with a mental health condition (MHC). However, several studies have noted increasing trends in psychotropic prescribing for this age group, especially in antidepressant prescribing. In Australia, the vast majority of psychotropic medications prescribed to young people come from the general practice setting. To assess whether Australian General Practitioners (GPs) are prescribing in accordance with clinical guideline recommendations, this study examined trends in GP prescribing of psychotropic medications to young patients aged 16-24 years...
June 6, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28583103/in-patient-costs-of-agitation-and-containment-in-a-mental-health-catchment-area
#12
Antoni Serrano-Blanco, Maria Rubio-Valera, Ignacio Aznar-Lou, Luisa Baladón Higuera, Karina Gibert, Alfredo Gracia Canales, Lisette Kaskens, José Miguel Ortiz, Luis Salvador-Carulla
BACKGROUND: There is a scarce number of studies on the cost of agitation and containment interventions and their results are still inconclusive. We aimed to calculate the economic consequences of agitation events in an in-patient psychiatric facility providing care for an urban catchment area. METHODS: A mixed approach combining secondary analysis of clinical databases, surveys and expert knowledge was used to model the 2013 direct costs of agitation and containment events for adult inpatients with mental disorders in an area of 640,572 adult inhabitants in South Barcelona (Spain)...
June 6, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28583100/insomnia-psychiatric-disorders-and-suicidal-ideation-in-a-national-representative-sample-of-active-canadian-forces-members
#13
J D Richardson, A Thompson, L King, B Corbett, P Shnaider, K St Cyr, C Nelson, J Sareen, J Elhai, M Zamorski
BACKGROUND: Past research on the association between insomnia and suicidal ideation (SI) has produced mixed findings. The current study explored the relationship between insomnia, SI, and past-year mental health status among a large Canadian Forces (CF) sample. METHOD: Data was obtained from the 2013 Canadian Forces Mental Health Survey (CFMHS), and included a large representative sample of Canadian Regular Forces personnel (N = 6700). A series of univariate logistic regressions were conducted to test individual associations between past-year mental health status, insomnia, and potential confounds and SI...
June 6, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28583098/contours-of-a-causal-feedback-mechanism-between-adaptive-personality-and-psychosocial-function-in-patients-with-personality-disorders-a-secondary-analysis-from-a-randomized-clinical-trial
#14
Ole Klungsøyr, Bjørnar Antonsen, Theresa Wilberg
BACKGROUND: Patients with personality disorders commonly exhibit impairment in psychosocial function that persists over time even with diagnostic remission. Further causal knowledge may help to identify and assess factors with a potential to alleviate this impairment. Psychosocial function is associated with personality functioning which describes personality disorder severity in DSM-5 (section III) and which can reportedly be improved by therapy. METHODS: The reciprocal association between personality functioning and psychosocial function was assessed, in 113 patients with different personality disorders, in a secondary longitudinal analysis of data from a randomized clinical trial, over six years...
June 5, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28578682/secondary-distress-in-violence-researchers-a-randomised-trial-of-the-effectiveness-of-group-debriefings
#15
Heidi Grundlingh, Louise Knight, Dipak Naker, Karen Devries
BACKGROUND: Secondary distress including emotional distress, vicarious trauma (VT) and secondary traumatic stress (STS) due to exposure to primary trauma victims have been described in helping professionals and in violence researchers. To our knowledge, there are few prevalence studies, and no tailored interventions have been tested to reduce secondary distress in violence researchers. The study aims to (1) describe the epidemiology of secondary distress experienced by violence researchers; to (2) assess the effectiveness of group debriefings in mitigating secondary distress; to (3) assess risk and protective factors...
June 2, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28578671/serious-child-and-adolescent-behaviour-disorders-a-valuation-study-by-professionals-youth-and-parents
#16
Karin M Vermeulen, Daniëlle E M C Jansen, Erik Buskens, Erik J Knorth, Sijmen A Reijneveld
BACKGROUND: In child and youth care, quantitative estimates of the impact of serious behaviour problems have not yet been made. Such input is needed to support decision making on investments in treatment. The aim of this paper was to elicit valuations of social and conduct disorders in children and adolescents from three different perspectives: professionals, youth, and parents. METHODS: We obtained valuations from 25 youth care professionals, 50 children (age 9-10) without serious behaviour problems and 36 adolescents (age 16-17) with and without serious behaviour disorders, and 46 parents with children in the aforementioned age categories...
June 2, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28578666/affected-family-members-experience-of-and-coping-with-aggression-and-violence-within-the-context-of-problematic-substance-use-a-qualitative-study
#17
Terence V McCann, Dan I Lubman, Gayelene Boardman, Mollie Flood
BACKGROUND: Families have an important role supporting a family member with problematic substance use (PSU), although this can often be challenging and confronting. Previous research has identified high rates of family aggression and violence within the context of PSU, although few studies have examined this issue from the perspective of affected family members (AFMs) supporting a member with PSU. The aims of the current study were to understand AFMs' experience of aggression and violence while supporting a member with PSU, and to explicate the strategies they used to prevent and cope with this behaviour...
June 2, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28578665/risk-factors-for-dementia-in-the-ninth-decade-of-life-and-beyond-a-study-of-the-lothian-birth-cohort-1921
#18
Ruth A Sibbett, Tom C Russ, Ian J Deary, John M Starr
BACKGROUND: With increasing numbers of people surviving beyond eighty years, this section of the population demands attention to reduce the impact of dementia. In order to develop effective preventative strategies, it is essential to understand age-specific risk factor profiles for dementia: do risk factors for dementia in those in their sixties and seventies persist into oldest age? The aims of this study were to determine incident dementia and to investigate the risk profile for dementia from age 79 to 95 years in a well-characterised cohort...
June 2, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28577550/study-protocol-of-the-asd-net-the-german-research-consortium-for-the-study-of-autism-spectrum-disorder-across-the-lifespan-from-a-better-etiological-understanding-through-valid-diagnosis-to-more-effective-health-care
#19
Inge Kamp-Becker, Luise Poustka, Christian Bachmann, Stefan Ehrlich, Falk Hoffmann, Philipp Kanske, Peter Kirsch, Sören Krach, Frieder Michel Paulus, Marcella Rietschel, Stefan Roepke, Veit Roessner, Tanja Schad-Hansjosten, Tania Singer, Sanna Stroth, Stephanie Witt, Anne-Kathrin Wermter
BACKGROUND: Autism Spectrum Disorder (ASD) is a severe, lifelong neurodevelopmental disorder with early onset that places a heavy burden on affected individuals and their families. Due to the need for highly specialized health, educational and vocational services, ASD is a cost-intensive disorder, and strain on health care systems increases with increasing age of the affected individual. METHODS: The ASD-Net will study Germany's largest cohort of patients with ASD over the lifespan...
June 2, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28576133/adherence-healthcare-resource-utilization-and-medicaid-spending-associated-with-once-monthly-paliperidone-palmitate-versus-oral-atypical-antipsychotic-treatment-among-adults-recently-diagnosed-with-schizophrenia
#20
Dominic Pilon, Erik Muser, Patrick Lefebvre, Rhiannon Kamstra, Bruno Emond, Kruti Joshi
BACKGROUND: Once-monthly paliperidone palmitate (PP1M) is a long-acting injectable antipsychotic that may increase adherence rates, reduce hospitalizations, and lower medical costs compared to oral atypical antipsychotics (OAAs) among schizophrenia patients. However, the impact of PP1M in recently diagnosed patients remains unknown. The present study compared adherence, healthcare resource utilization and Medicaid spending between schizophrenia patients initiating PP1M versus OAA, among patients recently diagnosed (defined using ages 18-25 years as a proxy) and among the overall population...
June 2, 2017: BMC Psychiatry
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