Jie Feng, Wenjiao Min, Dandan Wang, Jing Yuan, Junming Chen, Lisha Chen, Wei Chen, Meng Zhao, Jia Cheng, Chunling Wan, Bo Zhou, Yulan Huang, Yaoyin Zhang
BACKGROUND: The diagnosis of adolescent Depressive Disorder (DD) lacks specific biomarkers, posing significant challenges. This study investigates the potential of Niacin Skin Flush Response (NSFR) as a biomarker for identifying and assessing the severity of adolescent Depressive Disorder, as well as distinguishing it from Behavioral and Emotional Disorders typically emerging in childhood and adolescence(BED). METHODS: In a case-control study involving 196 adolescents, including 128 Depressive Disorder, 32 Behavioral and Emotional Disorders, and 36 healthy controls (HCs), NSFR was assessed...
April 17, 2024: BMC Psychiatry