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BMC Cardiovascular Disorders

M Skowerski, I Wozniak-Skowerska, A Hoffmann, S Nowak, T Skowerski, M Sosnowski, A M Wnuk-Wojnar, K Mizia-Stec
BACKGROUND: It has been suggested that changes in pulmonary veins (PV) and left atrium (LA) anatomy may have an influence on initiating atrial fibrillation (AF) and the effectiveness of pulmonary vein isolation (PVI) in patients (pts) with atrial fibrillation. The aim of the study was to assess anatomy abnormalities of the PV and LA in the patients with the history of AF and compare it with the control group(CG). METHODS: The multi-slice tomography (MSCT) scans were performed in 224 AF pts...
July 13, 2018: BMC Cardiovascular Disorders
M P Graham-Brown, A S Singh, G S Gulsin, E Levelt, J A Arnold, D J Stensel, J O Burton, G P McCann
BACKGROUND: Extent of myocardial fibrosis (MF) determined using late gadolinium enhanced (LGE) predicts outcomes, but gadolinium is contraindicated in advanced renal disease. We assessed the ability of native T1-mapping to identify and quantify MF in aortic stenosis patients (AS) as a model for use in haemodialysis patients. METHODS: We compared the ability to identify areas of replacement-MF using native T1-mapping to LGE in 25 AS patients at 3 T. We assessed agreement between extent of MF defined by LGE full-width-half-maximum (FWHM) and the LGE 3-standard-deviations (3SD) in AS patients and nine T1 thresholding-techniques, with thresholds set 2-to-9 standard-deviations above normal-range (1083 ± 33 ms)...
July 13, 2018: BMC Cardiovascular Disorders
Tejas P Singh, Tristan Skalina, Daniel Nour, Aarya Murali, Sean Morrison, Joseph V Moxon, Jonathan Golledge
BACKGROUND: The xanthine oxidase inhibitor allopurinol that is commonly used to treat gout, has been suggested to have pleiotropic effects that are likely to reduce the incidence of myocardial infarction (MI) in at risk individuals. The aim of this meta-analysis was to assess the efficacy of allopurinol treatment in reducing the incidence of MI. METHOD: MEDLINE, Scopus, Web of Science, and Cochrane Library databases were searched for randomised controlled trials examining the efficacy of allopurinol in reducing the incidence of MI...
July 11, 2018: BMC Cardiovascular Disorders
Michael Dandel, Roland Hetzer
The potential life-threatening consequences of catecholamine use for emergency circulatory support in Takotsubo cardiomyopathy-related acute heart failure is a major challenge in cardiovascular emergences. In their recent work in BMC Cardiovascular Disorders Ansari U. et al. demonstrated the harmful effects of catecholamines on the outcome of patients with Takotsubo cardiomyopathy. Concerning this matter we emphasize the usefulness of speckle-tracking-derived echocardiography for early recognition of an acute phase of a Takotsubo syndrome in order to avoid the deleterious effects of a catecholamine therapy in patients with Takotsubo-associated acute heart failure...
July 11, 2018: BMC Cardiovascular Disorders
Jae Yeong Cho, Kye Hun Kim, Hyukjin Park, Hyun Ju Yoon, Jong Chun Park
BACKGROUND: Intracardiac invasion of head and neck cancer is extremely rare. Here, we report a case of recurred oral cavity cancer presenting with complete atrioventricular (AV) block caused by cardiac metastasis. CASE PRESENTATION: A 70-year-old male presented with dizziness for 2 days. He had a history of oral cavity cancer a year ago, and the tumor was treated by surgical excision after induction chemotherapy and concurrent chemoradiation therapy. Electrocardiography showed complete AV block with ventricular escape rate of 43 beats per minute...
July 9, 2018: BMC Cardiovascular Disorders
Shuo Yang, Li Sheng Zhao, Chuan Cai, Quan Shi, Ning Wen, Juan Xu
BACKGROUND: Inflammation is a common feature of both peripheral arterial disease (PAD) and periodontitis. Some studies have evaluated the association between PAD and periodontitis. However, there is still no specialized meta-analysis that has quantitatively assessed the strength of the association. Thus, we conducted this meta-analysis to critically assess the strength of the association between PAD and periodontitis. METHODS: PubMed, Embase, and the Cochrane Library were searched for observational studies of the association between periodontitis and PAD in February 2018...
July 6, 2018: BMC Cardiovascular Disorders
Yong Wang, Mou-Jie Liu, Hui-Min Yang, Chun-Yan Ma, Peng-Yu Jia, Da-Lin Jia, Ai-Jie Hou
BACKGROUND: Despite marked advances in our understanding of the pathophysiology of the coronary slow flow phenomenon (CSFP), the exact mechanism remains unclear. Previous studies have suggested that CSFP might be associated with generalized atherosclerosis, endothelial dysfunction, and low-grade chronic inflammation. High serum alkaline phosphatase (ALP) levels are associated with vascular calcification, atherosclerotic disease, and an increased risk of cardiovascular events. However, the relationship between ALP and CSFP is unclear...
July 4, 2018: BMC Cardiovascular Disorders
Stephen Jan, Stephen W-L Lee, Jitendra P S Sawhney, Tiong K Ong, Chee Tang Chin, Hyo-Soo Kim, Rungroj Krittayaphong, Vo T Nhan, Stuart J Pocock, Ana M Vega, Nobuya Hayashi, Yong Huo
BACKGROUND: The EPICOR Asia (long-tErm follow-uP of antithrombotic management patterns In acute CORonary syndrome patients in Asia) study (NCT01361386) was an observational study of patients hospitalized for acute coronary syndromes (ACS) enrolled in 218 hospitals in eight countries/regions in Asia. This study examined costs, length of stay and the predictors of high costs during an ACS hospitalization. METHODS AND RESULTS: Data for patients hospitalized for an ACS (n = 12,922) were collected on demographics, medical history, event characteristics, socioeconomic and insurance status at discharge...
July 4, 2018: BMC Cardiovascular Disorders
Giovanni Farello, Annarita Antenucci, Stefano Stagi, Chiara Mazzocchetti, Franco Ciocca, Alberto Verrotti
BACKGROUND: The cardiovascular disease risk was assessed in metabolically healthy obese (MHO) children, obese children with metabolic disorders (MUO), and to a control group of normal-weight children using carotid intima-media thickness (CIMT). METHODS: Participants were 204 obese children (114 M, 90 F), including 162 MUO (74 M, 88 F) and 42 MHO (24 M, 18 F), and 99 gender- and age-matched controls (45 M, 54 F). Glucose, triglycerides, total cholesterol, high-density and low-density lipoprotein cholesterol, and other serum values were determined in peripheral blood...
July 4, 2018: BMC Cardiovascular Disorders
Tetsuya Yamamoto, Tsuneaki Kenzaka, Masanori Matsumoto, Ryo Nishio, Satoru Kawasaki, Hozuka Akita
BACKGROUND: Viral myocarditis presents with various symptoms, including fatal arrhythmia and cardiogenic shock, and may develop into chronic myocarditis and dilated cardiomyopathy in some patients. We report a case of viral myocarditis and hepatitis caused by herpes simplex virus. CASE PRESENTATION: A 20-year-old woman was admitted to our hospital with fever, fatigue, and anorexia. The initial investigation showed elevated liver enzyme levels and elevated creatine phosphokinase, and computed tomography showed diffuse swelling and internal heterogeneous image in the liver...
July 3, 2018: BMC Cardiovascular Disorders
Sherri Schwaninger, John Musuku, Mark E Engel, Patrick Musonda, Joyce Chipili Lungu, Elizabeth Machila, Agnes Mtaja, Evans Mulendele, Dorothy Kavindele, Jonathan Spector, Brigitta Tadmor, Marcelo M Gutierrez, Joris Van Dam, Laurence Colin, Aidan Long, Mark C Fishman, Bongani M Mayosi, Liesl J Zühlke
BACKGROUND: The large global burden of rheumatic heart disease (RHD) has come to light in recent years following robust epidemiologic studies. As an operational research component of a broad program aimed at primary and secondary prevention of RHD, we sought to determine the current prevalence of RHD in the country's capital, Lusaka, using a modern imaging-based screening methodology. In addition, we wished to evaluate the practicality of training local radiographers in echocardiography screening methods...
July 3, 2018: BMC Cardiovascular Disorders
Wanyu Wang, Ailing Song, Yiming Zeng, Xiaoyang Chen, Yixiang Zhang, Yonghong Shi, Yihua Lin, Wen Luo
BACKGROUND: To explore the effects of chronic intermittent hypoxia (CIH), which mimics sleep apnea syndrome, on the cardiac renin angiotensin system (RAS), and to investigate the cardiac protection of an angiotensin receptor blocker (ARB)telmisartan (TERT) against CIH. METHODS: 32 healthy male C57B6J mice were randomly divided into CIH, ARB, blank and air control groups. CIH lasted for 12 weeks. Cardiac angiotensin converting enzyme (ACE), angiotensin converting enzyme 2 (ACE 2) and angiotensin II (Ang II) were evaluated by immunohistochemistry...
July 3, 2018: BMC Cardiovascular Disorders
Susanne S Pedersen, Søren J Skovbakke, Uffe K Wiil, Thomas Schmidt, Rene dePont Christensen, Carl J Brandt, Jan Sørensen, Michael Vinther, Charlotte E Larroudé, Thomas M Melchior, Sam Riahi, Kim G E Smolderen, John A Spertus, Jens B Johansen, Jens C Nielsen
BACKGROUND: In Denmark and other countries, there has been a shift in the management of patients with an implantable cardioverter defibrillator (ICD) with remote device monitoring largely replacing in-hospital visits. Less patient-nurse and patient-physician interaction may lead to gaps in patients' quality of care and impede patients' adaptation to living successfully with the ICD. A comprehensive eHealth intervention that include goal-setting, monitoring of symptoms of depression, anxiety, and quality of life, psychological treatment, information provision, supportive tools, online dialogues with nursing staff and access to an online community network, may help fill these gaps and be particularly beneficial to patients who suffer from anxiety and depression...
July 3, 2018: BMC Cardiovascular Disorders
Ehsan Razmara, Masoud Garshasbi
BACKGROUND: Myosin VI, encoded by MYH6, is expressed dominantly in human cardiac atria and plays consequential roles in cardiac muscle contraction and comprising the cardiac muscle thick filament. It has been reported that the mutations in the MYH6 gene associated with sinus venosus atrial septal defect (ASD type III), hypertrophic (HCM) and dilated (DCM) cardiomyopathies. METHODS: Two patients in an Iranian family have been identified who affected to Congenital Heart Disease (CHD)...
July 3, 2018: BMC Cardiovascular Disorders
Jeehoon Kang, Kyung Woo Park, Michael S Lee, Chengbin Zheng, Jung-Kyu Han, Han-Mo Yang, Hyun-Jae Kang, Bon-Kwon Koo, Hyo-Soo Kim
BACKGROUND: Nonculprit lesions are the major cause of future cardiovascular events. However, the natural course of nonculprit lesions and angiographic predictors of plaque progression are not well-studied. The purpose of our study was to observe the natural course of nonculprit lesions, and to identify predictors of unanticipated future events and angiographic progression in nonculprit lesions. METHODS: We analyzed 640 nonculprit lesions with a length of ≥2 mm and luminal narrowing ≥30% from 320 patients who had two serial angiographic follow-ups; 9 to 13 months post-PCI and 24 months post-PCI...
June 28, 2018: BMC Cardiovascular Disorders
Claudius Hansen, Christian Loges, Karlheinz Seidl, Frank Eberhardt, Herbert Tröster, Krum Petrov, Gerian Grönefeld, Peter Bramlage, Frank Birkenhauer, Christian Weiss
BACKGROUND: In heart failure (HF) patients with implantable cardioverter defibrillators (ICD) or cardiac resynchronisation therapy defibrillators (CRT-D), remote monitoring has been shown to result in at least non-inferior outcomes relative to in-clinic visits. We aimed to provide further evidence for this effect, and to assess whether adding telephone follow-ups to remote follow-ups influenced outcomes. METHODS: InContact was a prospective, randomised, multicentre study...
June 28, 2018: BMC Cardiovascular Disorders
Yash R Patel, Jeremy M Robbins, Katherine E Kurgansky, Tasnim Imran, Ariela R Orkaby, Robert R McLean, Yuk-Lam Ho, Kelly Cho, J Michael Gaziano, Luc Djousse, David R Gagnon, Jacob Joseph
BACKGROUND: Heart failure (HF) with preserved ejection fraction (HFpEF) comprises nearly half of prevalent HF, yet is challenging to curate in a large database of electronic medical records (EMR) since it requires both accurate HF diagnosis and left ventricular ejection fraction (EF) values to be consistently ≥50%. METHODS: We used the national Veterans Affairs EMR to curate a cohort of HFpEF patients from 2002 to 2014. EF values were extracted from clinical documents utilizing natural language processing and an iterative approach was used to refine the algorithm for verification of clinical HFpEF...
June 28, 2018: BMC Cardiovascular Disorders
Zbigniew Malota, Jan Glowacki, Wojciech Sadowski, Marcin Kostur
BACKGROUND: The stenosis of the coronary arteries is usually caused by atherosclerosis. Hemodynamic significance of patient-specific coronary stenoses and the risk of its progression may be assessed by comparing the hemodynamic effects induced by flow disorders. The present study shows how stenosis degree and variable flow conditions in coronary artery affect the oscillating shear index, residence time index, pressure drop coefficient and fractional flow reserve. We assume that changes in the hemodynamic indices in relation to variable flow conditions and geometries evaluated using the computational fluid dynamics may be an additional factor for a non-invasive assessment of the coronary stenosis detected on multi-slice computed tomography...
June 28, 2018: BMC Cardiovascular Disorders
Shirvan Salaminia, Fatemeh Sayehmiri, Parvin Angha, Koroush Sayehmiri, Morteza Motedayen
BACKGROUND: Atrial and ventricular cardiac arrhythmias are one of the most common early complications after cardiac surgery and these serve as a major cause of mortality and morbidity after cardiac revascularization. We want to evaluate the effect of magnesium sulfate administration on the incidence of cardiac arrhythmias after cardiac revascularization by doing this systematic review and meta-analysis. METHODS: The search performed in several databases (SID, Magiran, IranDoc, IranMedex, MedLib, PubMed, EmBase, Web of Science, Scopus, the Cochrane Library and Google Scholar) for published Randomized controlled trials before December 2017 that have reported the association between Magnesium consumption and the incidence of cardiac arrhythmias...
June 28, 2018: BMC Cardiovascular Disorders
Satoshi Higuchi, Yusuke Kabeya, Kenichi Matsushita, Keisei Tachibana, Riken Kawachi, Hidefumi Takei, Yutaka Suzuki, Nobutsugu Abe, Yorihisa Imanishi, Kiyoshi Moriyama, Tomoko Yorozu, Koichiro Saito, Masanori Sugiyama, Haruhiko Kondo, Hideaki Yoshino
BACKGROUND: A previous retrospective cohort study established the relationship between perioperative atrial fibrillation (POAF) and subsequent mortality and stroke. However, the details regarding the cause of death and etiology of stroke remain unclear. METHODS: The prospective cohort study of surveillance for perioperative atrial fibrillation recurrence in major non-cardiac surgery for malignancy (PREDICT AF RECURRENCE) registry is an ongoing prospective cohort study to elucidate the long-term recurrence rate and the clinical impact of new-onset POAF in the setting of head and neck, non-cardiac thoracic, and abdominal surgery for malignancy...
June 26, 2018: BMC Cardiovascular Disorders
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