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BMC Cardiovascular Disorders

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https://www.readbyqxmd.com/read/29776386/impact-of-vkorc1-cyp4f2-and-nqo1-gene-variants-on-warfarin-dose-requirement-in-han-chinese-patients-with-catheter-ablation-for-atrial-fibrillation
#1
Jiao Li, Wenlong Yang, Zhonghui Xie, Kun Yu, Yuhua Chen, Kaijun Cui
BACKGROUND: The anticoagulation of atrial fibrillation catheter ablation during the perioperative stage does matter and should be treated with discretion. We aimed to assess impact of three important genes participating in vitamin K cycle (i.e. VKORC1 rs9923231, CYP4F2 rs2108622 and NQO1 rs1800566) on the daily stable warfarin dose requirement in Sichuan Han Chinese patients with catheter ablation of atrial fibrillation. METHODS: A total of 222 atrial fibrillation patients taking stable warfarin therapy after catheter ablation operation were enrolled in this study...
May 18, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29776337/should-statin-guidelines-consider-patient-preferences-eliciting-preferences-of-benefit-and-harm-outcomes-of-statins-for-primary-prevention-of-cardiovascular-disease-in-the-sub-saharan-african-and-european-contexts
#2
Henock G Yebyo, Hélène E Aschmann, Tsung Yu, Milo A Puhan
BACKGROUND: Patient preferences are key parameters to evaluate benefit-harm balance of statins for primary prevention but they are not readily available to guideline developers and decision makers. Our study aimed to elicit patient preferences for benefit and harm outcomes related to use of statins for primary cardiovascular disease prevention and to examine how the preferences differ across economically and socio-culturally different environments. METHODS: We conducted preference-eliciting surveys using best-worst scaling designed with a balanced incomplete-block design (BIBD) on 13 statins-related outcomes on 220 people in Ethiopia and Switzerland...
May 18, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29769031/presentation-and-outcomes-of-indigenous-australians-with-peripheral-artery-disease
#3
Tejas P Singh, Joseph V Moxon, Genevieve N Healy, Yvonne Cadet-James, Jonathan Golledge
BACKGROUND: The risk factors for peripheral artery disease (PAD) are more common in Indigenous than non-Indigenous Australians, however the presentation and outcome of PAD in Indigenous Australians has not been previously investigated. The aim of this prospective cohort study was to compare the presenting characteristics and clinical outcome of Indigenous and non-Indigenous Australians with PAD. METHODS: PAD patients were prospectively recruited and followed-up since 2003 from an outpatient vascular clinic in Townsville, Australia...
May 16, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29769019/comparison-of-outcomes-in-emergency-department-patients-with-suspected-cardiac-chest-pain-two-centre-prospective-observational-study-in-southern-china
#4
Huilin Jiang, Yunmei Li, Junrong Mo, Xiaohui Chen, Min Li, Peiyi Lin, Kevin K C Hung, Timothy H Rainer, Colin A Graham
BACKGROUND: Hong Kong (HK) and Guangzhou (GZ) are cities in China with different healthcare systems. This study aimed to compare 30-day and 6-month mortality and characteristics of patients with suspected cardiac chest pain admitted to two emergency departments (ED) in HK and GZ. METHODS: A prospective observational study enrolled patients with suspected cardiac chest pain presenting to EDs in the Prince of Wales Hospital (PWH), HK and the Second Affiliated Hospital of Guangzhou Medical University (AHGZMU),GZ...
May 16, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29747569/systolic-characteristics-and-dynamic-changes-of-the-mitral-valve-in-different-grades-of-ischemic-mitral-regurgitation-insights-from-3d-transesophageal-echocardiography
#5
Caroline Morbach, Diego Bellavia, Stefan Störk, Lissa Sugeng
BACKGROUND: Mitral regurgitation in ischemic heart disease (IMR) is a strong predictor of outcome but until now, pathophysiology is not sufficiently understood and treatment is not satisfying. We aimed to systematically evaluate structural and functional mitral valve leaflet and annular characteristics in patients with IMR to determine the differences in geometric and dynamic changes of the MV between significant and mild IMR. METHODS: Thirty-seven patients with IMR (18 mild (m)MR, 19 significant (moderate+severe) (s)MR) and 33 controls underwent TEE...
May 10, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29743025/risk-of-incident-atrial-fibrillation-in-patients-presenting-with-retinal-artery-or-vein-occlusion-a-nationwide-cohort-study
#6
Christine Benn Christiansen, Christian Torp-Pedersen, Jonas Bjerring Olesen, Gunnar Gislason, Morten Lamberts, Nicholas Carlson, Mathias Buron, Nikolai Juul, Gregory Y H Lip
BACKGROUND: The inter-relationships of atrial fibrillation (AF) to retinal vascular occlusions (whether retinal artery occlusion (RAO) or retinal venous occlusion (RVO)) remain unclear. It is unknown if a presentation of retinal artery or venous occlusions may indicate a new onset cardiac arrhythmia. To shed light on this association, we investigated the risk of new onset AF in patients with known RAO and RVO. METHODS: Patients with retinal occlusions from 1997 to 2011 were identified through Danish nationwide registries and matched 1:5 according to sex and age...
May 10, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29743023/three-years-outcomes-of-diabetic-patients-treated-with-coronary-bioresorbable-scaffolds
#7
Remzi Anadol, Katharina Schnitzler, Liv Lorenz, Melissa Weissner, Helen Ullrich, Alberto Polimeni, Thomas Münzel, Tommaso Gori
BACKGROUND: Diabetes is among the strongest predictors of outcome after coronary artery stenting and the incidence of negative outcomes is still high in this specific group. Data of long-term outcomes comparing diabetic patients with non-diabetic patients treated with bioresorbable scaffolds are still incomplete. This work evaluates the long-term outcomes after implantation of a coronary bioresorbable scaffold (BRS) in diabetic patients compared to non-diabetics. METHODS: Patients who received at least one Absorb BRS in the time of May 2012 to December 2014 were enrolled into this single-center registry...
May 10, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29739333/renal-denervation-improves-cardiac-function-by-attenuating-myocardiocyte-apoptosis-in-dogs-after-myocardial-infarction
#8
Li Wang, Lijun Song, Chao Li, Qiaoli Feng, Mengping Xu, Zhuqing Li, Chengzhi Lu
BACKGROUND: Myocardial apoptosis is important in the pathogenesis and progression of myocardial infarction-induced heart failure (MI-HF). Renal sympathetic denervation (RDN) has become a promising therapeutic strategy for the treatment of HF. Previous studies have shown that RDN could improve heart function Yao et al. (Exp Ther Med 14:4104-4110, 2017). However, whether and how RDN regulates myocardial apoptosis in MI-HF is unclear. This study sought to evaluate the effects of RDN on cardiac function and apoptosis-related gene expression in MI-HF dogs...
May 8, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29739328/a-novel-ultrafast-low-dose-computed-tomography-protocol-allows-concomitant-coronary-artery-evaluation-and-lung-cancer-screening
#9
Carlo Gaudio, Gennaro Petriello, Francesco Pelliccia, Alessandra Tanzilli, Alberto Bandiera, Gaetano Tanzilli, Francesco Barillà, Vincenzo Paravati, Massimo Pellegrini, Enrico Mangieri, Paolo Barillari
BACKGROUND: Cardiac computed tomography (CT) is often performed in patients who are at high risk for lung cancer in whom screening is currently recommended. We tested diagnostic ability and radiation exposure of a novel ultra-low-dose CT protocol that allows concomitant coronary artery evaluation and lung screening. METHODS: We studied 30 current or former heavy smoker subjects with suspected or known coronary artery disease who underwent CT assessment of both coronary arteries and thoracic area (Revolution CT, General Electric)...
May 8, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29739326/the-impact-of-nontraditional-lipid-profiles-on-left-ventricular-geometric-abnormalities-in-general-chinese-population
#10
Haoyu Wang, Zhao Li, Xiaofan Guo, Yintao Chen, Ye Chang, Shuang Chen, Yingxian Sun
BACKGROUND: Despite current interest in the unfavorable impact of nontraditional lipid profiles on cardiovascular disease, information regarding its relations to abnormal left ventricular (LV) geometry has not been systemically elucidated. This study sought to understand predictive implication of nontraditional lipid profiles in specific LV geometric patterns in the general population of rural China. METHODS: Analyses were based upon a cross-sectional study of 10,756 participants (mean age 53...
May 8, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29739318/safety-of-cilostazol-in-peripheral-artery-disease-a-cohort-from-a-primary-healthcare-electronic-database
#11
Jordi Real, M Catalina Serna, Maria Giner-Soriano, Rosa Forés, Guillem Pera, Esther Ribes, Maite Alzamora, Josep Ramon Marsal, Antonio Heras, Rosa Morros
BACKGROUND: Cilostazol has been associated with spontaneous reports of cardiovascular adverse events and serious bleeding. The objective of this study is to determine the relative risk of cardiovascular adverse events or haemorrhages in patients with peripheral artery disease treated with cilostazol in comparison to pentoxifylline users. METHODS: Population-based cohort study including all individuals older than 40 who initiated cilostazol or pentoxifylline during 2009-2011 in SIDIAP database...
May 8, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29739317/novel-functional-advanced-echocardiography-for-the-assessment-of-myocardial-mechanics-in-children-with-neurocardiogenic-syncope-a-blinded-prospective-speckle-tracking-head-up-tilt-table-challenge-study
#12
Kai O Hensel, Markus Roskopf, Francisca Abellan Schneyder, Andreas Heusch
BACKGROUND: Data on left ventricular (LV) function in patients with neurocardiogenic syncope (NS) is conflicting in adults and lacking in children. The aim of this study was to analyze LV myocardial performance in children with NS at rest and during head-up tilt-table (HUTT) testing. METHODS: This is the first study to combine HUTT and speckle-tracking echocardiography (STE) in children with NS. 43 consecutive normotensive pediatric patients with NS (mean age 13...
May 8, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29739314/association-between-skeletal-muscle-mass-to-visceral-fat-area-ratio-and-arterial-stiffness-in-chinese-patients-with-type-2-diabetes-mellitus
#13
Jing Xu, Xiaoyan Pan, Haili Liang, Yi Lin, Yilian Hong, Qiya Si, Feixia Shen, Xuejiang Gu
BACKGROUND: The skeletal muscle mass-to-visceral fat area ratio (SVR) has been linked to arterial stiffness in non-diabetic adults. We examined the association between the SVR and arterial stiffness in patients with type 2 diabetes mellitus (T2DM). METHODS: Patients with type 2 diabetes mellitus (252 men and 171 women) aged 40-75 years were enrolled and divided into three groups according to SVR tertiles. Arterial stiffness was measured as brachial-ankle pulse wave velocity (baPWV), with baPWV> 1800 mm/s defined as high...
May 8, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29728071/effect-of-blood-pressure-and-total-cholesterol-measurement-on-risk-prediction-using-the-systematic-coronary-risk-evaluation-score
#14
Sabina Ulbricht, Stefan Gross, Eva Brammen, Franziska Weymar, Ulrich John, Christian Meyer, Marcus Dörr
BACKGROUND: To compare the reproducibility in total cholesterol (TC), systolic blood pressure (BP), and the resulting Systematic COronary Risk Evaluation (SCORE) obtained by an in-office cardio-preventive screening program (SP) and a subsequent program performed in a clinical trial examination center (EP). METHODS: A total of 307 individuals (60.3% female, mean age = 52.8 years) participated. According to TC and BP measurements at the SP and EP, three variables were created: the SCORESP  = single BP reading at the SP, the SCOREEP/BP-first  = first BP reading at the EP, and the SCOREEP/BP-mean  = mean second/third BP reading at the EP...
May 4, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29728070/the-comorbidity-of-increased-arterial-stiffness-and-microalbuminuria-in-a-survey-of-middle-aged-adults-in-china
#15
Rujia Miao, Liuxin Wu, Ping Ni, Yue Zeng, Zhiheng Chen
BACKGROUND: Increased arterial stiffness (iAS) and microalbuminuria (MAU), which may occur simultaneously or separately in the general population and share similar risk factors, are markers of macro- and microvascular injuries. Our research investigated the comorbidity of iAS and MAU in the middle-aged population and examined the heterogeneous effects of metabolic risk factors on iAS and MAU. METHODS: We selected 11,911 individuals aged 45 to 60 years who underwent a health examination at the 3rd Xiangya Hospital between 2010 and 2014...
May 4, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29728065/prevalence-and-characteristics-of-primary-left-sided-valve-disease-in-a-cohort-of-15-000-patients-undergoing-echocardiography-studies-in-a-tertiary-hospital-in-uganda
#16
Joselyn Rwebembera, William Manyilirah, Zhang Wan Zhu, Juliet Nabbaale, Judith Namuyonga, Isaac Ssinabulya, Sulaiman Lubega, Peter Lwabi, John Omagino, Emmy Okello
BACKGROUND: Although rheumatic heart disease remains the leading cause of valve heart disease (VHD) in developing countries, other forms of valve disease have been over shadowed and not regarded as a public health problem. However, several facts suggest that the role of non-rheumatic VHD as a significant cardiovascular disease should be reconsidered. We aimed to assess the prevalence and characteristics of different forms of primary left sided valve diseases from a series of 15,009 echocardiographic studies...
May 4, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29728052/a-new-method-for-the-assessment-of-endothelial-function-with-peripheral-arterial-volume
#17
Daoyuan Si, Lujia Ni, Yunfei Wang, Jinsha Liu, Jining Yang, Ping Yang
BACKGROUND: Currently, many methodological approaches have been developed to assess peripheral endothelial function. However, a development of the noninvasive and automated technique for routinely assessing endothelial function is still required. We evaluated the potential value of a new method to measure peripheral endothelial function with reactive hyperemia peripheral arterial volume (RH-PAV) in patients with chest pain. METHODS: We used a novel oximeter-like probe to detect the peripheral arterial volume (PAV) of the finger and compared it with brachial flow-mediated dilation (FMD) performed in 93 consecutive patients with chest pain...
May 4, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29724164/signs-symptoms-and-treatment-patterns-across-serial-ambulatory-cardiology-visits-in-patients-with-heart-failure-insights-from-the-ncdr-pinnacle%C3%A2-registry
#18
Larry A Allen, Fengming Tang, Philip Jones, Tracie Breeding, Angelo Ponirakis, Stuart J Turner
BACKGROUND: Due to a relative lack of outpatient heart failure (HF) clinical registries, we aimed to describe symptoms, signs, and medication treatment among ambulatory patients with heart failure (HF) over time. METHODS: Using health records from 234 PINNACLE (Practice Innovation and Clinical Excellence) U.S. cardiology practices (2008-2014), serial visits for patients with HF were characterized. Symptoms, signs, and HF medications (angiotensin-converting enzyme inhibitors [ACEI], angiotensin receptor blockers [ARB], beta blockers [BB], and diuretics) were compared between visits...
May 3, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29720097/-as-du-coeur-study-a-randomized-controlled-trial-on-physical-activity-maintenance-in-cardiovascular-patients
#19
Marion Fournier, Rémi Radel, Laurent Bailly, Christian Pradier, Roxane Fabre, Alain Fuch, Philippe Mossé, Jean-Jacques Domerego, Jocelyn Gal, Fabienne d'Arripe-Longueville
BACKGROUND: The benefits of supervised physical activity programs in cardiac rehabilitation have been amply demonstrated, but the quantity of physical activity often declines quickly once supervision ends. This trial assesses the effectiveness of an experimental intervention drawing on habit formation theory to maintain physical activity. METHODS: Cardiovascular patients (N = 47) were randomly assigned to one of two groups. The first group participated in two supervised physical activity (SPA) sessions per week for 20 weeks...
May 2, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29720092/post-percutaneous-coronary-interventional-adverse-cardiovascular-outcomes-and-bleeding-events-observed-with-prasugrel-versus-clopidogrel-direct-comparison-through-a-meta-analysis
#20
Pravesh Kumar Bundhun, Feng Huang
BACKGROUND: Due to limitations associated with clopidogrel following percutaneous coronary intervention (PCI), other newer oral anti-platelet agents are being studied. We aimed to systematically carry out a direct comparison of outcomes observed with prasugrel versus clopidogrel following PCI. METHODS: Common online searched databases (The Cochrane library, EMBASE, MEDLINE and Google scholar) were used to retrieve relevant publications. Primary endpoints were the adverse cardiovascular outcomes...
May 2, 2018: BMC Cardiovascular Disorders
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