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BMC Cardiovascular Disorders

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https://www.readbyqxmd.com/read/28420368/outcomes-following-percutaneous-coronary-revascularization-among-south-asian-and-chinese-canadians
#1
Martha H Mackay, Robinder Singh, Robert H Boone, Julie E Park, Karin H Humphries
BACKGROUND: Previous data suggest significant ethnic differences in outcomes following percutaneous coronary revascularization (PCI), though previous studies have focused on subgroups of PCI patients or used administrative data only. We sought to compare outcomes in a population-based cohort of men and women of South Asian (SA), Chinese and "Other" ethnicity. METHODS: Using a population-based registry, we identified 41,792 patients who underwent first revascularization via PCI in British Columbia, Canada, between 2001 and 2010...
April 19, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28420337/right-aortic-arch-analysis-anatomical-variant-or-serious-vascular-defect
#2
Agata Arazińska, Michał Polguj, Konrad Szymczyk, Magdalena Kaczmarska, Łukasz Trębiński, Ludomir Stefańczyk
BACKGROUND: The right-sided aortic arch (RAA) is a rare congenital defect of the aorta. The aim of the study was to assess the occurrence of RAA in diagnoses performed by the University Radiology Department and analyze the frequency of concomitant vascular abnormalities. METHODS: The database of the Radiology Department was retrospectively analyzed between January 2008 and May 2016 with the keyword "right aortic arch". Twenty patients with this diagnosis were identified from a total of 11,690 CT examinations of the chest area, 19,623 CT examinations of brain-supplying vessels, and 1863 MRI examinations of the heart and aortic arch or brain-supplying arteries...
April 19, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28410571/pre-and-post-surgical-evaluation-of-the-inflammatory-response-in-patients-with-aortic-stenosis-treated-with-different-types-of-prosthesis
#3
Maria Elena Soto, Jose Luis Salas, Jesus Vargas-Barron, Ricardo Marquez, Alejandra Rodriguez-Hernandez, Rafael Bojalil-Parra, Israel Pérez-Torres, Veronica Guarner-Lans
BACKGROUND: The inflammatory process in aortic valvular stenosis persists after surgery to replace the valve in almost half of the patients. No association has been found to its persistence. The main objective of this study was to evaluate the inflammatory response in patients with aortic stenosis through the determination of several biomarkers in plasma measured before and after the valvular replacement and to seek an association with the type of prosthesis used. METHODS: This is an observational study with a follow up of 6 months in subjects with severe aortic stenosis...
April 14, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28407744/global-bi-ventricular-endocardial-distribution-of-activation-rate-during-long-duration-ventricular-fibrillation-in-normal-and-heart-failure-canines
#4
Qingzhi Luo, Qi Jin, Ning Zhang, Yanxin Han, Yilong Wang, Shangwei Huang, Changjian Lin, Tianyou Ling, Kang Chen, Wenqi Pan, Liqun Wu
BACKGROUND: The objective of this study was to detect differences in the distribution of the left and right ventricle (LV & RV) activation rate (AR) during short-duration ventricular fibrillation (SDVF, <1 min) and long-duration ventricular fibrillation VF (LDVF, >1 min) in normal and heart failure (HF) canine hearts. METHODS: Ventricular fibrillation (VF) was electrically induced in six healthy dogs (control group) and six dogs with right ventricular pacing-induced congestive HF (HF group)...
April 13, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28390413/does-stress-perfusion-imaging-improve-the-diagnostic-accuracy-of-late-gadolinium-enhanced-cardiac-magnetic-resonance-for-establishing-the-etiology-of-heart-failure
#5
Gaurav S Gulsin, Abishek Shetye, Jeffrey Khoo, Daniel J Swarbrick, Eylem Levelt, Florence Y Lai, Iain B Squire, Jayanth R Arnold, Gerry P McCann
BACKGROUND: Late gadolinium enhanced cardiovascular magnetic resonance (LGE-CMR) has excellent specificity, sensitivity and diagnostic accuracy for differentiating between ischemic cardiomyopathy (ICM) and non-ischemic dilated cardiomyopathy (NICM). CMR first-pass myocardial perfusion imaging (perfusion-CMR) may also play role in distinguishing heart failure of ischemic and non-ischemic origins, although the utility of additional of stress perfusion imaging in such patients is unclear...
April 8, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28381298/ticagrelor-versus-clopidogrel-in-real-world-patients-with-st-elevation-myocardial-infarction-1-year-results-by-propensity-score-analysis
#6
Matteo Vercellino, Federico Ariel Sànchez, Valentina Boasi, Dino Perri, Chiara Tacchi, Gioel Gabrio Secco, Stefano Cattunar, Gianfranco Pistis, Giovanni Mascelli
BACKGROUND: European guidelines recommend the use of ticagrelor versus clopidogrel in patients with ST elevation myocardial infarction (STEMI). This recommendation is based on inconclusive results and subanalyses from clinical trials. Few data are available on the effects of ticagrelor in a real-world population. METHODS: To compare the effects of ticagrelor and clopidogrel in a real-world STEMI population, we conducted a pre-post case-control study examining all patients with STEMI included in the Cardio-STEMI Sanremo registry between February 2011 and June 2013...
April 5, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28381282/coronary-sinus-aneurysm-associated-with-multiple-venous-anomalies
#7
Guang Song, Ming Du, Weidong Ren, Ke Zhou, Lu Sun
BACKGROUND: Congenital anomalies of the venous system are rare, involve the inferior vena cava (IVC), a persistent left superior vena cava (PLSVC), and the left hepatic vein (LHV), and can make cardiac diagnostic and therapeutic procedures difficult. CASE PRESENTATION: We present a 67-year-old woman without heterotaxy syndrome associated with interruption of the left IVC that continued with the hemiazygos vein system, a PLSVC, and an anomalous LHV draining the into coronary sinus (CS)...
April 5, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28381265/thiazolidinedione-use-and-atrial-fibrillation-in-diabetic-patients-a-meta-analysis
#8
Zhiwei Zhang, Xiaowei Zhang, Panagiotis Korantzopoulos, Konstantinos P Letsas, Gary Tse, Mengqi Gong, Lei Meng, Guangping Li, Tong Liu
BACKGROUND: Accumulating evidence suggests that thiazolidinediones (TZDs) may exert protective effects in atrial fibrillation (AF). The present meta-analysis investigated the association between TZD use and the incidence of AF in diabetic patients. METHODS: Electronic databases were searched until December 2016. Of the 346 initially identified records, 3 randomized clinical trials (RCTs) and 4 observational studies with 130,854 diabetic patients were included in the final analysis...
April 5, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28381258/metabolomic-profiling-in-patients-undergoing-off-pump-or-on-pump-coronary-artery-bypass-surgery
#9
H Kirov, M Schwarzer, S Neugebauer, G Faerber, M Diab, T Doenst
BACKGROUND: Coronary artery bypass surgery can be performed without (Off-Pump) or with cardiopulmonary bypass (On-Pump). Extracorporeal circulation and cardioplegic arrest may cause alterations in the plasma metabolome. We assessed metabolomic changes in patients undergoing On-Pump or Off-Pump coronary artery bypass surgery. METHODS: We assessed five analyte classes (41 acylcarnitines, 14 amino acids, 92 glycerophospholipids, 15 sphingolipids, sugars, lactate) using a mass-spectrometry-based kit (Biocrates AbsoluteIDQ® p150) in paired arterial and coronary sinus blood obtained from 10 consecutive On-Pump and 10 Off-Pump patients...
April 5, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28381215/a-case-of-successful-reperfusion-through-a-combination-of-intracoronary-thrombolysis-and-aspiration-thrombectomy-in-st-segment-elevation-myocardial-infarction-associated-with-an-ectatic-coronary-artery
#10
Yonggu Lee, Eunjin Kim, Bae Keun Kim, Jeong-Hun Shin
BACKGROUND: Large thrombus burdens in ectatic coronary arteries that remain after aspiration thrombectomy can negatively impact outcomes following percutaneous coronary interventions in patients with acute myocardial infarction. CASE PRESENTATION: A 53-year-old man presented with ST-segment elevation myocardial infarction (STEMI). Coronary angiography revealed an ectatic right coronary artery (RCA) that was completely occluded in the mid portion by a large amount of thrombus...
April 5, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28376720/dynamic-changes-of-paraoxonase-1-activity-towards-paroxon-and-phenyl-acetate-during-coronary-artery-surgery
#11
Anna Wysocka, Marek Cybulski, Henryk Berbeć, Andrzej Wysokiński, Janusz Stążka, Jadwiga Daniluk, Tomasz Zapolski
BACKGROUND: Serum paraoxonase 1 (PON1), an enzyme associated with high - density lipoproteins (HDL) particles, inhibits the oxidation of serum lipoproteins and cell membranes. PON1 activity is lower in patients with atherosclerosis and in inflammatory diseases. The systemic inflammatory response provoked during cardiopulmonary bypass grafting may contribute to the development of postoperative complications. The aim of the present study was to estimate the dynamic changes in paraoxonase 1 (PON1) activity towards paraoxon and phenyl acetate during and after coronary artery surgery...
April 4, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28376710/electrocardiographic-changes-mimicking-acute-coronary-syndrome-in-a-large-intracranial-tumour-a-diagnostic-dilemma
#12
Nilukshana Yogendranathan, H M M T B Herath, S P Pahalagamage, Aruna Kulatunga
BACKGROUND: ST elevation Myocardial infarction is a medical emergency. A variety of noncardiac conditions had been known to mimic the ECG changes that are seen in acute coronary syndrome. Although the common ECG changes that are documented with raised intracranial pressure are T inversions, prolongation of QT interval and sinus bradycardia, ST elevation or depression, arrhythmias and prominent U waves have also been recognized. However, ST elevations in association with primary intracranial tumours are rarely reported...
April 4, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28359298/monocyte-lymphocyte-ratio-predicts-the-severity-of-coronary-artery-disease-a-syntax-score-assessment
#13
Hanhua Ji, Yang Li, Zeyuan Fan, Bo Zuo, Xinwen Jian, Li Li, Tao Liu
BACKGROUND: We aimed to explore whether monocyte to lymphocyte ratio (MLR) provides predictive value of the lesion severity in patients with coronary artery disease (CAD). METHODS: Five hundred forty-three patients undergoing coronary angiography were analyzed in this retrospective study. Patients with coronary stenosis were divided into three groups on the basis of Syntax score. The control group consisted of patients with normal coronary arteries. MLR was calculated by dividing monocytes count by lymphocytes count obtained from routine blood examination...
March 31, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28340568/chronic-lymphocytic-leukemia-skin-infiltration-mimicking-an-icd-pocket-infection-a-case-report
#14
M Snorek, A Bulava, I Vonke
BACKGROUND: We are presenting a case report on an unreported and unusual cutaneous manifestation of chronic lymphocytic leukemia in a patient with an implantable cardioverter-defibrillator (ICD). CASE PRESENTATION: A 65-year-old man with a history of chronic lymphocytic leukemia (CLL), previously treated with chlorambucil, was referred in October 2013 for extraction of a single chamber ICD due to a suspected device-related infection in the pulse generator area (left-hand side of Fig...
March 24, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28335740/mir-21-enhances-cardiac-fibrotic-remodeling-and-fibroblast-proliferation-via-cadm1-stat3-pathway
#15
Wei Cao, Peng Shi, Jian-Jun Ge
BACKGROUND: Cardiac fibrosis play a key role in the atrial fibrillation pathogenesis but the underlying potential molecular mechanism is still understood. However, potential mechanisms for miR-21 upregulation and its role in cardiac fibrosis remain unclear. The controls cell proliferation and processes fundamental to disease progression. METHODS: In this study, immunohistochemistry, real-time RT-PCR, cell transfection, cell cycle, cell proliferation and Western blot were used, respectively...
March 23, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28335730/auscultatory-versus-oscillometric-blood-pressure-measurement-in-patients-with-atrial-fibrillation-and-arterial-hypertension
#16
Aistėja Šelmytė-Besusparė, Jūratė Barysienė, Dovilė Petrikonytė, Audrius Aidietis, Germanas Marinskis, Aleksandras Laucevičius
BACKGROUND: The aim of our study was to investigate the reliability of automated oscillometric blood pressure (BP) monitoring in the presence and absence of atrial fibrillation (AF) in hypertensive patients. METHODS: BP was measured and compared in 71 randomly selected patients with AF and arterial hypertension diagnosis, 4 times each by auscultatory and oscillometric (Microlife BP A6 PC with AF detection system) methods. RESULTS: Study included 71 patients: 36 males (mean age 67...
March 23, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28330445/cardiac-amyloidosis-mimicking-severe-aortic-valve-stenosis-a-case-report-demonstrating-diagnostic-pitfalls-and-role-of-dobutamine-stress-echocardiography
#17
Tim Salinger, Kai Hu, Dan Liu, Sebastian Herrmann, Kristina Lorenz, Georg Ertl, Peter Nordbeck
BACKGROUND: Aortic valve stenosis is a common finding diagnosed with high sensitivity in transthoracic echocardiography, but the examiner often finds himself confronted with uncertain results in patients with moderate pressure gradients and concomitant systolic heart failure. While patients with true-severe low-gradient aortic valve stenosis with either reduced or preserved left ventricular systolic function are primarily candidates for valve replacement, there is a relevant proportion of patients with pseudo-severe aortic valve stenosis anticipated not to benefit but actually rather deteriorate by interventional therapy or surgery...
March 22, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28320316/clinical-outcomes-of-conventional-surgery-versus-mitraclip%C3%A2-therapy-for-moderate-to-severe-symptomatic-mitral-valve-regurgitation-in-the-elderly-population-an-institutional-experience
#18
Anthony Alozie, Liliya Paranskaya, Bernd Westphal, Alexander Kaminski, Mohammad Sherif, Magnus Sindt, Stephan Kische, Jochen Schubert, Doreen Diedrich, Hüseyin Ince, Gustav Steinhoff, Alper Öner
BACKGROUND: The aim of this study was to compare treatment of moderate to severe symptomatic mitral regurgitation (MR) with either conventional surgery or the mitral valve edge-to-edge device (MitraClip®) in very elderly patients. The newly introduced MitraClip device has demonstrated promising acute results in treating this patient cohort. Also noteworthy is the fact that patients who otherwise would have been denied surgery are increasingly referred for treatment with the MitraClip device...
March 20, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28302055/comparing-stent-thrombosis-associated-with-zotarolimus-eluting-stents-versus-everolimus-eluting-stents-at-1%C3%A2-year-follow-up-a-systematic-review-and-meta-analysis-of-6-randomized-controlled-trials
#19
Pravesh Kumar Bundhun, Chandra Mouli Yanamala, Wei-Qiang Huang
BACKGROUND: Two thousand fifteen has been a winning year for Drug Eluting Stents (DES). Increase in the number of patients with cardiovascular diseases treated by Percutaneous Coronary Intervention (PCI) has resulted to a high demand for second generation DES. This current analysis aimed to compare the different types of Stent Thrombosis (ST) associated with Zotarolimus Eluting Stents (ZES) versus Everolimus Eluting Stents (EES) at 1 year follow up. METHODS: Electronic databases were searched for studies comparing ZES with EES...
March 16, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28298191/bleeding-events-associated-with-a-low-dose-110%C3%A2-mg-versus-a-high-dose-150%C3%A2-mg-of-dabigatran-in-patients-treated-for-atrial-fibrillation-a-systematic-review-and-meta-analysis
#20
Pravesh Kumar Bundhun, Nabin Chaudhary, Jun Yuan
BACKGROUND: The newer oral anticoagulant dabigatran is considered to be more beneficial in patients with non-valvular Atrial Fibrillation (AF) when compared to warfarin. However, because bleeding events which are associated with a low dose (110 mg) versus a high dose (150 mg) of dabigatran have seldom been compared, we aimed to systematically solve this important issue through this meta-analysis. METHODS: English publications comparing 110 mg with 150 mg dabigatran in patients who were treated for AF were electronically searched through medical databases...
March 15, 2017: BMC Cardiovascular Disorders
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