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BMC Cardiovascular Disorders

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https://www.readbyqxmd.com/read/28818058/evaluation-of-therapy-management-and-outcome-in-takotsubo-syndrome
#1
Nadine Abanador-Kamper, Lars Kamper, Judith Wolfertz, Witali Pomjanski, Anamaria Wolf-Pütz, Melchior Seyfarth
BACKGROUND: To date there is no validated evidence for standardized treatment of patients with Takotsubo syndrome (TTS). Medication therapy after final TTS diagnosis remains unclear. Previous data on patient outcome is ambivalent. Aim of this study was to evaluate medication therapy in TTS and to analyze patient outcome. METHODS: Within an observational retrospective cohort study we analyzed our medical records and included 72 patients with TTS that underwent cardiovascular magnetic resonance imaging (CMR) after a median of 2 days interquartile range (IQR 1-3...
August 17, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28814290/predicted-impact-of-lipid-lowering-therapy-on-cardiovascular-and-economic-outcomes-of-swedish-atherosclerotic-cardiovascular-disease-guideline
#2
Gunilla Journath, Kristina Hambraeus, Emil Hagström, Billie Pettersson, Mickael Löthgren
BACKGROUND: The effects on cardiovascular disease (CVD) by treatment recommendations on prevention of atherosclerotic CVD remain to be evaluated. The objectives were to assess treatment gap for low density lipoprotein cholesterol (LDL-C) according to guidelines, potential impact on CVD outcomes, and possible avoided economic costs, in post myocardial infarction (MI) patients, if target LDL-C levels of ≤1.8 mmol/L would be achieved. METHODS: All patients registered in the Swedish Secondary Prevention after Heart Intensive care Admission register, with one-year post-MI follow-up during 2013 were selected...
August 16, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28814264/left-ventricular-contractile-reserve-by-stress-echocardiography-as-a-predictor-of-response-to-cardiac-resynchronization-therapy-in-heart-failure-a-systematic-review-and-meta-analysis
#3
Quirino Ciampi, Clara Carpeggiani, Claudio Michelassi, Bruno Villari, Eugenio Picano
BACKGROUND: The presence of left ventricular contractile reserve (LVCR) during stress echo (SE) may provide favorable response to cardiac resynchronization therapy (CRT) in heart failure patients. The aim of the study was to perform a meta-analysis of available SE data in this set of patients. METHODS: From a Pubmed and Advance Google Scholar database web based search scan up to December 2016, we initially identified 5906 records. From this initial set, we removed that did not include SE and duplicate studies...
August 16, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28810900/polymer-free-dual-drug-eluting-stents-evaluated-in-a-porcine-model
#4
Bin Zhang, Bo Zheng, Xingang Wang, Qiuping Shi, Jia Jia, Yong Huo, Chunshui Pan, Jingyan Han, Ming Chen
BACKGROUND: Although drug-eluting stents have dramatically reduced the rates of restenosis and target lesion revascularization, they are associated with stent thrombosis (ST), a catastrophic event likely due to delayed endothelialization and chronic inflammation caused by the polymer and the metal scaffolds. To increase the safety and efficacy of stents, polymer-free dual drug-eluting stents (DDES) have been developed. METHODS: A total 160 stents (Bare-metal stents (BMS), polymer-free probucol stents (PrES), sirolimus-eluting stents (SES) and DDES) were randomly implanted in the coronary arteries of 80 pigs...
August 15, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28800733/integrative-and-quantitive-evaluation-of-the-efficacy-of-his-bundle-related-pacing-in-comparison-with-conventional-right-ventricular-pacing-a-meta-analysis
#5
Ziqing Yu, Ruizhen Chen, Yangang Su, Xueying Chen, Shengmei Qin, Minghui Li, Fei Han, Junbo Ge
BACKGROUND: Long-term RVP could bring adverse problems to cardiac electro-mechanics and result in inter- and intra-ventricular asynchrony, impaired labor force, and aggravation of cardiac function. HBRP including direct His bundle pacing and para-His bundle pacing was regarded as a novel physiological pacing pattern to avoid devastating cardiac function. This synthetic study was conducted to integratively and quantitatively evaluate the efficacy of His bundle related pacing (HBRP) in comparison with conventional right ventricular pacing (RVP)...
August 11, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28793864/in-vitro-examination-of-the-positive-inotropic-effect-of-caffeine-and-taurine-the-two-most-frequent-active-ingredients-of-energy-drinks
#6
R Chaban, A Kornberger, N Branski, K Buschmann, N Stumpf, A Beiras-Fernandez, C F Vahl
BACKGROUND: Our study aimed to evaluate changes in the contractile behavior of human myocardium after exposure to caffeine and taurine, the main active ingredients of energy drinks (EDs), and to evaluate whether taurine exhibits any inotropic effect at all in the dosages commonly used in EDs. METHODS: Myocardial tissue was removed from the right atrial appendages of patients undergoing cardiac surgery and prepared to obtain specimens measuring 4 mm in length. A total of 92 specimens were exposed to electrical impulses at a frequency of 75 bpm for at least 40 min to elicit their maximum contractile force before measuring the isometric contractile force (ICF) and duration of contraction (CD)...
August 10, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28789617/left-ventricular-longitudinal-function-assessment-in-rabbits-after-acute-occlusion-of-left-anterior-descending-coronary-artery-by-two-dimensional-speckle-tracking-imaging
#7
Jun Huang, Zi-Ning Yan, Li Fan, Yi-Fei Rui, Xiang-Ting Song
ABSTACT: BACKGROUND: To evaluate the left ventricular (LV) longitudinal function changes in rabbits after acute occlusion of the left anterior descending artery (LAD) by two-dimensional speckle tracking imaging (2D-STI). METHODS: Forty-eight New Zealand white rabbits underwent echocardiography examination. EchoPAC was used to measure LV peak systolic longitudinal strain (LS) of the endocardium, middle myocardium, and epicardium, peak longitudinal strain rate (LSr), segmental and global longitudinal rotation (LR) degrees...
August 8, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28789616/models-for-improved-diagnosis-of-left-ventricular-hypertrophy-based-on-conventional-electrocardiographic-criteria
#8
Nan Lu, Jin-Xiu Zhu, Pei-Xuan Yang, Xue-Rui Tan
BACKGROUND: Electrocardiogram (ECG) is commonly used clinically due to convenience, but its accuracy is insufficient for left ventricular hypertrophy (LVH) diagnosis. In this study, we attempted to improve diagnostic accuracy of LVH by establishing models with ECG parameters. METHODS: Eighty hundred and twenty eight patients were recruited in the present study which were divided into groups according to gender, age and body mass index (BMI). The sensitivity, specificity, Youden index, positive predictive value, negative predictive value and accuracy were calculated using ultrasonic cardiogram criteria of LVH as the gold standard...
August 8, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28789613/risk-factors-of-metabolic-syndrome-among-hypertensive-patients-at-hawassa-university-comprehensive-specialized-hospital-southern-ethiopia
#9
Agete Tadewos, Tariku Egeno, Antenah Amsalu
BACKGROUND: Data regarding the prevalence of metabolic syndrome (MetS) among hypertensive patients in Ethiopia is very scarce, and the nature and the burden of MetS among these patients has not been well investigated. Therefore, the aim of this study was to assess the pattern and risk factors of MetS in hypertensive patients. METHODS: A cross-sectional study was conducted at Hawassa University comprehensive specialized hospital from September 2015 to June 2016. Data on socio-demographic, clinical and anthropometric characteristics were collected from 238 hypertensive participants using WHO stepwise technique...
August 8, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28778146/effect-of-increased-left-ventricle-mass-on-ischemia-assessment-in-electrocardiographic-signals-rabbit-isolated-heart-study
#10
Marina Ronzhina, Veronika Olejnickova, Tibor Stracina, Marie Novakova, Oto Janousek, Jakub Hejc, Jana Kolarova, Miroslava Hlavacova, Hana Paulova
BACKGROUND: Detailed quantitative analysis of the effect of left ventricle (LV) hypertrophy on myocardial ischemia manifestation in ECG is still missing. The associations between both phenomena can be studied in animal models. In this study, rabbit isolated hearts with spontaneously increased LV mass were used to evaluate the effect of such LV alteration on ischemia detection criteria and performance. METHODS: Electrophysiological effects of increased LV mass were evaluated on sixteen New Zealand rabbit isolated hearts under non-ischemic and ischemic conditions by analysis of various electrogram (EG) parameters...
August 4, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28774268/prognostic-value-of-short-term-follow-up-bnp-in-hospitalized-patients-with-heart-failure
#11
Sayma Sabrina Khanam, Jung-Woo Son, Jun-Won Lee, Young Jin Youn, Junghan Yoon, Seung-Hwan Lee, Jang-Young Kim, Sung Gyun Ahn, Min-Soo Ahn, Byung-Su Yoo
BACKGROUND: B-type natriuretic peptide (BNP) has prognostic significance in heart failure (HF), and reductions in BNP may predict clinical improvement. However, there are limited data regarding the prognostic value of BNP during short-term follow-up. The aim of this study was to evaluate the relationship between short-term follow-up BNP and mortality after discharge in patients with HF. METHODS: We analyzed 427 patients hospitalized with HF from the Wonju Severance Christian Hospital Heart Failure Registry from April 2011 to December 2013, with a planned follow-up period through February 2016...
August 3, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28768478/left-ventricular-systolic-function-changes-in-hypertrophic-cardiomyopathy-patients-detected-by-the-strain-of-different-myocardium-layers-and-longitudinal-rotation
#12
Jun Huang, Zi-Ning Yan, Li Fan, Yi-Fei Rui, Xiang-Ting Song
BACKGROUND: Impairment of left ventricular (LV) longitudinal function has an important role in hypertrophic cardiomyopathy (HCM). This research investigated an association between the longitudinal strain of different myocardial layers, longitudinal rotation and the LV systolic function of HCM patients. METHODS: The research was performed on 36 HCM patients and 36 healthy subjects. The peak systolic longitudinal strain of the subendocardial, midmyocardial, and subepicardial layers was measured using 2-dimensional speckle tracking echocardiography (2D-STE)...
August 2, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28768475/the-cost-utility-of-point-of-care-troponin-testing-to-diagnose-acute-coronary-syndrome-in-primary-care
#13
Michelle M A Kip, Hendrik Koffijberg, Marco J Moesker, Maarten J IJzerman, Ron Kusters
BACKGROUND: The added value of using a point-of-care (POC) troponin test in primary care to rule out acute coronary syndrome (ACS) is debated because test sensitivity is inadequate early after symptom onset. This study investigates the potential cost-utility of diagnosing ACS by a general practitioner (GP) when a POC troponin test is available versus GP assessment only. METHODS: A patient-level simulation model was developed, representing a hypothetical cohort of the Dutch population (>35 years) consulting the GP with chest complaints...
August 2, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28764639/antithrombotic-treatment-during-coronary-angioplasty-after-failed-thrombolysis-strategies-and-prognostic-implications-results-of-the-respire-registry
#14
José M De la Torre Hernández, Mario Sadaba Sagredo, Miren Telleria Arrieta, Federico Gimeno de Carlos, Elena Sanchez Lacuesta, Juan A Bullones Ramírez, Javier Pineda Rocamora, Victoria Martin Yuste, Tamara Garcia Camarero, Mariano Larman, Jose R Rumoroso
BACKGROUND: Thrombolysis is still used when primary angioplasty is delayed for a long time, but 25%-30% of patients require rescue angioplasty (RA). There are no established recommendations for antithrombotic management in RA. This registry analyzes regimens for antithrombotic management. METHODS: A retrospective, multicenter, observational registry of consecutive patients treated with RA at 8 hospitals. All variables were collected and follow-up took place at 6 months...
August 1, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28760133/surface-ecg-interatrial-block-guided-treatment-for-stroke-prevention-rationale-for-an-attractive-hypothesis
#15
Antoni Bayés de Luna, Manuel Martínez-Sellés, Antoni Bayés-Genís, Roberto Elosua, Adrian Baranchuk
Atrial fibrillation (AF) is the most common sustained arrhythmia and is associated with stroke, cognitive impairment, and cardiovascular death. Some predisposing factors - as aging, diabetes, hypertension - induce and maintain electrophysiological and ultrastructural remodeling that usually includes fibrosis. Interatrial conduction disturbances play a crucial role in the initiation of atrial fibrosis and in its associated complications. The diagnosis of interatrial blocks (IABs) is easy to perform using the surface ECG...
July 31, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28754098/longitudinal-shortening-remains-the-principal-component-of-left-ventricular-pumping-in-patients-with-chronic-myocardial-infarction-even-when-the-absolute-atrioventricular-plane-displacement-is-decreased
#16
Daniel Asgeirsson, Erik Hedström, Jonas Jögi, Ulrika Pahlm, Katarina Steding-Ehrenborg, Henrik Engblom, Håkan Arheden, Marcus Carlsson
BACKGROUND: The majority (60%) of left ventricular (LV) stroke volume (SV) is generated by longitudinal shortening causing apical atrioventricular plane displacement (AVPD) in systole. The remaining SV is caused by radial inward motion of the epicardium both in the septal and the lateral wall. We aimed to determine if these longitudinal, septal and lateral contributions to LVSV are changed in patients with chronic myocardial infarction (MI). METHODS: Patients with a chronic (>3 months) ST-elevation MI in the left anterior descending (LAD, n = 20) or right coronary artery (RCA, n = 16) and healthy controls (n = 20) were examined with cardiovascular magnetic resonance (CMR)...
July 28, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28754090/association-of-serum-c1q-tnf-related-protein-3-ctrp-3-in-patients-with-coronary-artery-disease
#17
Shuhong Wang, Yuan Ling, Wei Liang, Linhui Shen
BACKGROUND: Recent studies have demonstrated that complement C1q tumor necrosis factor related proteins (CTRPs) have diverse biological influences on the cardiovascular system. CTRP 3 is a member of the CTRP superfamily, which may play a pivotal role in the pathogenesis of coronary artery disease (CAD). Here, we investigated whether serum levels of CTRP 3 are associated with the prevalence and the severity of CAD. METHODS: In this study, 145 eligible participants were included who underwent coronary angiography...
July 28, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28754088/a-novel-targeted-angiogenesis-technique-using-vegf-conjugated-magnetic-nanoparticles-and-in-vitro-endothelial-barrier-crossing
#18
Mark Christopher Arokiaraj
BACKGROUND: Vascular endothelial growth factor is well known for its angiogenesis potential. The study was performed to determine the possible pro-angiogenic role of magnetic nanoparticles coupled to VEGF in vitro and their capacity to cross an endothelial monolayer. This novel treatment technique for angiogenesis could be potentially useful for therapeutic purposes using magnetic nanoparticles. METHODS: Magnetic nanoparticles (MN) were synthesized and were conjugated with the vascular endothelial growth factor...
July 28, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28750662/impact-of-hypertension-with-or-without-diabetes-on-left-ventricular-remodeling-in-rural-chinese-population-a-cross-sectional-study
#19
Tan Li, Shuang Chen, Xiaofan Guo, Jun Yang, Yingxian Sun
BACKGROUND: The aim of this study was to assess the impact of hypertension with or without diabetes on left ventricular (LV) remodeling in rural Chinese population. METHODS: A total of 10,270 participants were classified into control group, hypertension without diabetes (HT) group, and hypertension with diabetes (HT + DM) group. We compared clinical characteristics and echocardiographic parameters, and used multivariable logistic regression analysis to assess the associations of interest...
July 27, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28750610/an-exploratory-study-on-the-efficacy-and-safety-of-a-bcaa-preparation-used-in-combination-with-cardiac-rehabilitation-for-patients-with-chronic-heart-failure
#20
Munenori Takata, Eisuke Amiya, Masafumi Watanabe, Yumiko Hosoya, Atsuko Nakayama, Takayuki Fujiwara, Masanobu Taya, Gaku Oguri, Kanako Hyodo, Naoko Takayama, Nami Takano, Tomoe Mashiko, Yukari Uemura, Issei Komuro
BACKGROUND: Sarcopenia is generally complicated with patients with chronic heart failure (CHF) and its presence negatively affects the course of heart failure, however effective nutritional intervention had not been elucidated yet. The primary objective of this study is to explore whether the addition of a branched-chain amino acid (BCAA) preparation for cardiac rehabilitation (CR) of patients with CHF further improves cardiopulmonary functions, skeletal muscle functions, and metabolism in comparison with conventional CR...
July 27, 2017: BMC Cardiovascular Disorders
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