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BMC Cardiovascular Disorders

Jian Song, Xue Chen, Yingying Zhao, Jing Mi, Xuesen Wu, Huaiquan Gao
BACKGROUND: Individuals with prehypertension are at higher risk of developing hypertension and cardiovascular diseases, while the interaction between factors may aggravate prehypertension risk. Therefore, this study aimed to evaluate the risk factors for prehypertension in Chinese middle-aged and elderly adults, and explore the potentially interactive effect of evaluated factors. METHODS: All the participants that came from a community based cross-sectional survey were investigated in Bengbu, China, by being interviewed with a questionnaire...
September 15, 2018: BMC Cardiovascular Disorders
Tongtong Yu, Chunyang Tian, Jia Song, Dongxu He, Jiake Wu, Zongyu Wen, Zhijun Sun, Zhaoqing Sun
BACKGROUND: Thyroid hormones deeply influence the cardiovascular system; however, the association between the fT3/fT4 ratio and the clinical outcome in euthyroid patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) is not well defined. Therefore, the present study aimed to assess the prognostic performance of the fT3/fT4 ratio in predicting the long-term prognosis in euthyroid patients with AMI undergoing PCI. METHODS: In a prospective cohort study with a 1-year follow-up, according to the clinical end point, 953 euthyroid individuals (61...
September 10, 2018: BMC Cardiovascular Disorders
Jorge Navarro-Pérez, Domingo Orozco-Beltran, Vicente Gil-Guillen, Vicente Pallares, Francisco Valls, Antonio Fernandez, Ana María Perez-Navarro, Carlos Sanchis, Alejandro Dominguez-Lucas, Jose M Martin-Moreno, Josep Redon, Maria Tellez-Plaza
BACKGROUND: Despite the epidemiological evidence about the relationship between diabetes, mortality and cardiovascular disease, information about the population impact of uncontrolled diabetes is scarce. We aimed to estimate the attributable risk associated with HbA1c levels for all-cause mortality and cardiovascular hospitalization. METHODS: Prospective study of subjects with diabetes mellitus using electronic health records from the universal public health system in the Valencian Community, Spain 2008-2012...
September 4, 2018: BMC Cardiovascular Disorders
Joseph Longino, Ashish Chaddha, Matthew M Kalscheur, Anne M Rikkers, Deepak V Gopal, Michael E Field, Jennifer M Wright
BACKGROUND: Atrial fibrillation (AF) may result in procedure cancellations and emergency department (ED) referrals for patients presenting for outpatient GI endoscopic procedures. Such cancellations and referrals delay patient care and can lead to inefficient use of resources. METHODS: All consecutive patients presenting in AF for a colonoscopy or upper endoscopy to the University of Wisconsin Digestive Health Center between October 2013 and September 2014 were defined as the pre-intervention group (Group 1)...
September 3, 2018: BMC Cardiovascular Disorders
Sai Lv, Wei Liu, Yujie Zhou, Yuyang Liu, Dongmei Shi, Yingxin Zhao, Xiaoli Liu
BACKGROUND: Coronary artery disease (CAD) is showing an increasing trend in young adults. Cigarette smoking has been shown to be a major cause of premature CAD. Previous studies have also shown that hyperuricemia (HUA) is associated with CAD; however, the interaction effect between HUA and smoking on CAD is uncertain. Therefore, this study was designed to determine the relationship and interactive effects of HUA and smoking on the risk of CAD in young adults ≤ 35 years of age. METHODS: In this observational study we consecutively included adults (18-35 years of age) with suspected CAD who underwent coronary angiography for the first time in our institution from January 2005 to December 2015...
August 31, 2018: BMC Cardiovascular Disorders
Jin-Sheng Wang, Yi-Gen Shen, Ri-Peng Yin, Saroj Thapa, Yang-Pei Peng, Kang-Ting Ji, Lian-Ming Liao, Jia-Feng Lin, Yang-Jing Xue
BACKGROUND: Patients with frequent premature ventricular contractions (PVCs) are often symptomatic. Catheter ablation was usually indicated to eliminate symptoms in patients with PVCs-induced cardiomyopathy. Currently, PVCs-ablation is also applied for patients with PVCs and no structural heart diseases (SHD); however, the safety and efficacy of ablation in these patients remains unclear. METHODS: In this retrospective study, data from patients who underwent ablation for PVCs from January 2010 to December 2016 at our hospital was retrieved...
August 31, 2018: BMC Cardiovascular Disorders
Yintao Chen, Xiaofan Guo, Guozhe Sun, Zhao Li, Liqiang Zheng, Yingxian Sun
BACKGROUND: Many previous clinical studies have reported that prolongation of the QT interval corrected for heart rate (QTc) is associated with an increased risk of sudden cardiac death and all-cause mortality. This study aimed to explore associations between serum electrolytes and QTc prolongation in the north-eastern Chinese rural general population. METHODS: We performed a cross-sectional study including 10,334 (4820 men and 5514 women) from the general population aged ≥35 years in the Liaoning Province from 2012 to 2013...
August 29, 2018: BMC Cardiovascular Disorders
Minghui Wang, Yujie Liu, Xiujun Zhou, Jia Zhou, Hong Zhang, Ying Zhang
BACKGROUND: Reliability of models for estimating pretest probability (PTP) of obstructive coronary artery disease (CAD) has not been investigated in individuals at low extreme of traditional risk factor (RF) burden. Thus, we sought to validate and compare CONFIRM score and Genders extended model (GEM) among these individuals. METHODS: We identified symptomatic individuals with 0 or 1 RF who underwent coronary calcium scan and coronary computed tomographic angiography (CCTA)...
August 29, 2018: BMC Cardiovascular Disorders
Rungroj Krittayaphong, Arjbordin Winijkul, Komsing Methavigul, Wattana Wongtheptien, Chaiyasith Wongvipaporn, Treechada Wisaratapong, Rapeephon Kunjara-Na-Ayudhya, Smonporn Boonyaratvej, Chulalak Komoltri, Pontawee Kaewcomdee, Ahthit Yindeengam, Piyamitr Sritara
BACKGROUND: Anticoagulation therapy is a standard treatment for stroke prevention in patients with non-valvular atrial fibrillation (NVAF) that have risk factors for stroke. However, anticoagulant increases the risk of bleeding, especially in Asians. We aimed to investigate the risk profiles and pattern of antithrombotic use in patients with NVAF in Thailand, and to study the reasons for not using warfarin in this patient population. METHODS: A nationwide multicenter registry of patients with NVAF was created that included data from 24 hospitals located across Thailand...
August 25, 2018: BMC Cardiovascular Disorders
Christine K Kissel, Guanmin Chen, Danielle A Southern, P Diane Galbraith, Todd J Anderson
BACKGROUND: Non-obstructive coronary artery disease (NOCAD) is a common finding on coronary angiography. Our goal was to evaluate the long-term prognosis of NOCAD patients with stable angina (SA). METHODS: The study cohort consisted of 7478 NOCAD patients with normal EF (≥ 50%), and SA who underwent coronary angiography between 1995 and 2012. We compared NOCAD patients (stenosis< 50%) with 10,906 patients with stable obstructive CAD (≥ 50%). The primary endpoint was all-cause mortality...
August 22, 2018: BMC Cardiovascular Disorders
Yoshito Kadoya, Kan Zen, Satoaki Matoba
BACKGROUND: Transplant renal artery stenosis (TRAS) is a serious complication after renal transplantation, leading to hypertension, deterioration in renal function, and/or graft loss. The incidence of TRAS reportedly varies from 1 to 23%, depending on its definition or diagnostic tools. The hemodynamic definition or therapeutic indication of TRAS is unclear. CASE PRESENTATION: A 66-year-old man with a history of diabetes, chronic kidney disease, and angina presented with a 2-week history of dyspnea and leg edema...
August 22, 2018: BMC Cardiovascular Disorders
Christian Fastner, Lea Hoffmann, Mohamed Aboukoura, Michael Behnes, Siegfried Lang, Martin Borggrefe, Ibrahim Akin, Christoph A Nienaber
BACKGROUND: The interventional left atrial appendage closure (LAAC) is a guideline-conform alternative to oral anticoagulation (OAC) in non-valvular atrial fibrillation patients with OAC ineligibility. It was aimed to directly compare two contemporary devices in a real-world patient population. METHODS: LAAC was conducted in two centres between 2010 and 2014 as well as between 2014 and 2017, respectively, in a standard fashion based on the specific manufacturer's recommendations...
August 20, 2018: BMC Cardiovascular Disorders
Edward C A Marks, Tom M Wilkinson, Chris M Frampton, Lorraine Skelton, Anna P Pilbrow, Tim G Yandle, Chris J Pemberton, Robert N Doughty, Gillian A Whalley, Chris J Ellis, Richard W Troughton, Maurice C Owen, Neil R Pattinson, Vicky A Cameron, A Mark Richards, Steven P Gieseg, Barry R Palmer
BACKGROUND: Development of collateral circulation in coronary artery disease is cardio-protective. A key process in forming new blood vessels is attraction to occluded arteries of monocytes with their subsequent activation as macrophages. In patients from a prospectively recruited post-acute coronary syndromes cohort we investigated the prognostic performance of three products of activated macrophages, soluble vascular endothelial growth factor (VEGF) receptors (sFlt-1 and sKDR) and pterins, alongside genetic variants in VEGF receptor genes, VEGFR-1 and VEGFR-2...
August 15, 2018: BMC Cardiovascular Disorders
Ping Zhu, Xin Zhou, Chenliang Zhang, Huakang Li, Zhihui Zhang, Zhiyuan Song
BACKGROUND: The Orsiro biodegradable polymer sirolimus-eluting stent (O-SES) is a new-generation biodegradable polymer drug-eluting stent with the thinnest strut thickness to date developed to improve the percutaneous treatment of patients with coronary artery disease. We perform a meta-analysis of randomized clinical trials (RCTs) comparing the efficacy and safety of an ultra-thin, Orsiro biodegradable polymer sirolimus-eluting stent (O-SES) compared with durable polymer drug-eluting stents (DP-DESs)...
August 15, 2018: BMC Cardiovascular Disorders
Halldora Ögmundsdottir Michelsen, Marie Nilsson, Fredrik Scherstén, Ingela Sjölin, Alexandru Schiopu, Margret Leosdottir
BACKGROUND: Cardiac rehabilitation improves prognosis after an acute myocardial infarction (AMI), however, the optimal method of implementation is unknown. The aim of the study was to evaluate the effect of individually-tailored, nurse-led cardiac rehabilitation on patient outcomes. METHOD: This single-centre retrospective observational study included 217 patients (62 ± 9 years, 73% men). All patients attended cardiac rehabilitation including at least two follow-up consultations with a nurse...
August 15, 2018: BMC Cardiovascular Disorders
Xiang-Fei Feng, Mu Chen, Jian Sun, Jie Sun, Bo Liang, Yi-Yong Sun, Yi-Gang Li
BACKGROUND: Pulmonary vein isolation (PVI), a cornerstone for catheter ablation of atrial fibrillation (AF), remains a complex and time-consuming procedure. Present study introduces a novel, circular-irrigated, deca-channel mapping and ablation catheter (CIDMA), describes the in vitro test results on feasibility, safety, and acute efficacy of the CIDMA catheter. METHODS: An assembled CIDMA catheter was subjected to a number of in vitro tests. With this catheter, ablation procedures were first performed in a pig's myocardial strips in vitro to determine the effects in unipolar or bipolar configuration...
August 15, 2018: BMC Cardiovascular Disorders
Zhouping Zou, Yamin Zhuang, Lan Liu, Bo Shen, Jiarui Xu, Wuhua Jiang, Zhe Luo, Jie Teng, Chunsheng Wang, Xiaoqiang Ding
BACKGROUND: The aim of the study was to explore associations between elevated red cell distribution width (RDW) and acute kidney injury (AKI) in patients undergoing cardiac surgery (CS-AKI). METHODS: Preoperative, intraoperative and postoperative data of 10,274 patients undergoing cardiac surgery, including demographic data, were prospectively collected from January 2009 to December 2014. Propensity score matching was used on the basis of clinical characteristics and preoperative variables...
August 14, 2018: BMC Cardiovascular Disorders
Anne Lambert-Kerzner, Charles Maynard, Marina McCreight, Amy Ladebue, Katherine M Williams, Kelty B Fehling, Steven M Bradley
BACKGROUND: The use of inappropriate elective Percutaneous Coronary Intervention (PCI) has decreased over time, but hospital-level variation in the use of inappropriate PCI persists. Understanding the barriers and facilitators to the implementation of Appropriate Use Criteria (AUC) guidelines may inform efforts to improve elective PCI appropriateness. METHODS: All hospitals performing PCI in Washington State were categorized by their use of inappropriate elective PCI in 2010 to 2013...
August 13, 2018: BMC Cardiovascular Disorders
Yingxu Ma, Fan Bai, Fen Qin, Yixi Li, Tao Tu, Chao Sun, Shenghua Zhou, Qiming Liu
BACKGROUND: There is a little evidence for the effects of catheter ablation (CA) on hard endpoints in patients with atrial fibrillation (AF) and heart failure (HF). METHODS: PubMed, Embase and Cochrane Library were searched for randomized controlled trials (RCTs) enrolling patients with AF and HF who were assigned to CA, rate control or medical rhythm control groups. This meta-analysis was performed by using random-effect models. RESULTS: Seven RCTs enrolling 856 participants were included in this meta-analysis...
August 13, 2018: BMC Cardiovascular Disorders
Oleg Borisenko, Jochen Müller-Ehmsen, JoAnn Lindenfeld, Erik Rafflenbeul, Christian Hamm
BACKGROUND: This study aimed to evaluate cost-utility of baroreflex activation therapy (BAT) using the Barostim neo™ device (CVRx Inc., Minneapolis, MN, USA) compared with optimized medical management in patients with advanced chronic heart failure (NYHA class III) who were not eligible for treatment with cardiac resynchronization therapy, from a statutory health insurance perspective in Germany over a lifetime horizon. METHODS: A decision analytic model was developed using the combination of a decision tree and the Markov process...
August 9, 2018: BMC Cardiovascular Disorders
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