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BMC Anesthesiology

Vivien Berthoud, Omar Ellouze, Maxime Nguyen, Maria Konstantinou, Serge Aho, Ghislain Malapert, Claude Girard, Pierre-Gregoire Guinot, Olivier Bouchot, Belaid Bouhemad
BACKGROUND: Minimal invasive heart surgery (MIHS) presents several benefits, but provides intense and prolonged post-operative pain. Our objective was to compare efficacy of serratus anterior plane block (SAPB) with continuous wound infiltration (CWI) for management of post-operative pain following MIHS. METHODS: It's retrospective, monocentric study between November 2016 to April 2017. The study was performed at the University hospital of Dijon, Burgundy, France...
October 20, 2018: BMC Anesthesiology
Weijuan Zhu, Riyong Zhou, Lulu Chen, Yuanqing Chen, Lvdan Huang, Yun Xia, Thomas J Papadimos, Xuzhong Xu
BACKGROUND: Proximal brachial plexus blocks can lead to an extended period of motor paralysis and delay the return of motor function. This could influence patient satisfaction, and extend hospitalizations. The aim of the study is to compare a selective distal nerve block of the arm to a proximal axillary block, both ultrasound-guided, in terms of their motor block intensity of the elbow. Our hypothesis is that a selective nerve block of the arm would result in a different motor block of the elbow, compared to the axillary block...
October 19, 2018: BMC Anesthesiology
Lei Chen, Liangrong Wang, Qian Zhuo, Qiong Zhang, Feifei Chen, Liling Li, Lina Lin
BACKGROUND: Postoperative cognitive dysfunction (POCD) is a common complication after cardiac surgery that influences the clinical outcomes and quality of life of patients. This study aimed to evaluate the effects of Shenmai injection (SMI) on POCD of patients who underwent cardiac valve replacement under cardiopulmonary bypass (CPB). METHODS: This prospective, randomized, controlled trial was conducted from September 2014 to January 2017. Eighty-eight patients receiving cardiac valve replacement under CPB were randomized into the control (C) or the SMI (S) group...
October 11, 2018: BMC Anesthesiology
Bei Wang, Shengjin Ge, Wanxia Xiong, Zhanggang Xue
BACKGROUND: Postoperative cognitive dysfunction (POCD) seriously reduces quality of life and is associated with increased morbidity and mortality. The causes and neuropathogenesis of POCD remain largely unknown. Resveratrol, a sirtuin 1 (Sirt1) activator, is a polyphenol compound found in red wine that has protective functions in neuropathology paradigms. Endoplasmic reticulum stress (ERS) is a primary cellular response that activates the unfolded protein response (UPR). ERS and UPR mediate molecular and biochemical mechanisms related to neurodegeneration; however, the roles of ERS and Sirt1 in POCD remain unclear...
October 10, 2018: BMC Anesthesiology
Vikas O'Reilly-Shah, Grant C Lynde
BACKGROUND: With the increasing occurrence of drug shortages, understanding the pharmacokinetics of alternative intrathecal opioid administration has gained importance. In particular, additional data are needed to comprehensively evaluate the analgesic properties of intrathecal hydromorphone in the laboring patient. In a phase 2 clinical trial, we set out to determine the median effective dose (ED50 ) and time to effectiveness for this drug in this population. METHODS: Using Dixon's up-and-down sequential allocation method, twenty women presenting for labor analgesia were prospectively enrolled...
October 5, 2018: BMC Anesthesiology
Soeren Wagner, Joerg Quente, Sven Staedtler, Katharina Koch, Tanja Richter-Schmidinger, Johannes Kornhuber, Harald Ihmsen, Juergen Schuettler
BACKGROUND: The obstructive sleep apnea syndrome (OSAS) is characterized by temporary cerebral hypoxia which can cause cognitive dysfunction. On the other hand, hypoxia induced neurocognitive deficits are detectable after general anesthesia. The objective of this study was to evaluate the impact of a high risk of OSAS on the postoperative cognitive dysfunction after intravenous anesthesia. METHODS: In this single center trial between June 2012 and June 2013 43 patients aged 55 to 80 years with an estimated hospital stay of at least 3 days undergoing surgery were enrolled...
October 2, 2018: BMC Anesthesiology
De-Jie Wang, I-Shan Lee, An-Hsun Chou, Chun-Yu Chen, Pei-Chi Ting, Yun-Hui Teng, Jr-Rung Lin, Hsin-I Tsai
BACKGROUND: The goal of this study was to evaluate the accuracy and interchangeability between continuous cardiac output (CO) measured by electrical velocimetry (COEv ) and continuous cardiac output obtained using the pulmonary thermodilution method (COPAC ) during living donor liver transplantation (LDLT). METHOD: Twenty-three patients were enrolled in this prospective observational study. CO was recorded by both two methods and compared at nine specific time points...
October 2, 2018: BMC Anesthesiology
Kyoung-Woon Joung, Hyeong Ryul Kim, Wook-Jong Kim, Ye Ji Lim, Jae Won Kim, Eun-Ho Lee, In-Cheol Choi
BACKGROUND: The analgesic effects of dexamethasone have been reported previously, and the present study determined the effects of preoperative dexamethasone on postoperative pain in patients who received thoracotomy. METHODS: Forty patients participated in this randomized, double-blind study. All patients received either dexamethasone via a 0.1 mg/kg intravenous bolus before anesthetic induction or an equal volume of saline. Postoperative analgesia was provided to both groups via epidural patient-controlled analgesia (PCA), which consisted of 250 μg of sufentanil in 250 mL of ropivacaine (0...
September 27, 2018: BMC Anesthesiology
Panpan Fang, Zhijun Zong, Yao Lu, Xiaoyu Han, Xuesheng Liu
BACKGROUND: The airway reflex such as cough is common accompanied with severe fluctuations of hemodynamics during emergence. This prospective double-blind randomized controlled trial tested the hypothesis that topical ropivacaine may reduce extubation response and postoperative sore throat. METHODS: Fifty-four patients undergoing thyroidectomy were randomly assigned to two groups. The patients in Group R were received 0.75% ropivacaine, which was sprayed on the tracheal mucosa, epiglottis, tongue base, and glottis to achieve uniform surface anesthesia...
September 27, 2018: BMC Anesthesiology
Do-Won Lee, Jiseok Baik, Giyoung Yun, Soeun Jeon, Hyae-Jin Kim, Eun-Soo Kim, Hyeon Jeong Lee, Jae-Young Kwon
BACKGROUND: To examine the response to an α2receptor agonist used as a sedative for patients using long-term selective α1 blockers. METHODS: Sixty-nine consecutive patients undergoing transurethral prostate resection or holmium laser resection of the prostateunder spinal anesthesia were divided into two groups; group N (n = 37), which did not receive α1 blockers, and group T (n = 32), which was administered tamsulosin for at least 1 month before the study...
September 27, 2018: BMC Anesthesiology
Maximilian Vondran, Senta Schack, Jens Garbade, Christian Binner, Meinhard Mende, Ardawan Julian Rastan, Michael Andrew Borger, Thomas Schroeter
BACKGROUND: Clostridium difficile (CD) is the most common pathogen causing nosocomial diarrhea. The clinical presentation ranges from mild diarrhea to severe complications, including pseudomembranous colitis, toxic megacolon, sepsis, and multi-organ failure. When the disease takes a fulminant course, death ensues rapidly in severe and complex cases. Preventive screening or current prophylactic therapies are not useful. Therefore, this study was conducted to detect risk factors for a fulminant CD infection (CDI) in patients undergoing cardiac surgery...
September 27, 2018: BMC Anesthesiology
Kai-Kai Guo, Cheng-Qi Deng, Gui-Jun Lu, Guo-Li Zhao
BACKGROUND: Morphine and oxycodone are considered as wide-spreadly used opioids for moderate/severe cancer pain. However, debate exists about the evidence regarding their relative tolerability and underlying results. METHODS: A systematic search of online electronic databases, including PubMed, Embase, Cochrane library updated on October 2017 were conducted. The meta-analysis was performed including the studies that were designed as randomized controlled trials...
September 24, 2018: BMC Anesthesiology
Tao Yan, Guo-Hua Zhang, Bao-Na Wang, Li Sun, Hui Zheng
BACKGROUND: Vascular endothelial growth factor (VEGF) and transforming growth factor-β (TGF-β) have been involved in tumor growth and metastasis. Sevoflurane may promote angiogenesis, whereas propofol can present an anti-angiogenic effect. In this study, we compared the effects of propofol/remifentanil-based total intravenous anesthesia (TIVA) and sevoflurane-based inhalational anesthesia on the release of VEGF-C and TGF-β, as well as recurrence- free survival (RFS) rates in the patients undergoing breast cancer surgery...
September 22, 2018: BMC Anesthesiology
Wei Yu, Zijian Wang, Dapeng Gao, Wei Zhang, Wen Jin, Xuesong Ma, Sihua Qi
BACKGROUND: A right-sided double-lumen tube (R-DLT) tends to obstruct the right upper lobe intraoperatively due to anatomical distortion during surgery. If the R-DLT is poorly matched with the patient's airway anatomy, it will not be possible to correctly replace the tube with a fiberoptic bronchoscope (FOB). In our study, we aimed to explore an efficient method for difficult repositioning caused by right upper lobe occlusion during surgery: repositioning the R-DLT from the right main bronchus into the left main bronchus...
September 18, 2018: BMC Anesthesiology
Ahmed Abdalla Mohamed, Tarek Ahmed Radwan, Mohamed Mahmoud Mohamed, Hatem Abdellatif Mohamed, Mohamed Farid Mohamed Elemady, Safinaz Hassan Osman, Tamer Fayez Safan, Tamer Mohamed Khair, Norhan Abdelaleem Ali, Rania Samir Fahmy, Mohamed Ibrahim Belita, Shady Rady Abdalla, Ahmed Abdelaziz Seleem, Ehab Mohi Atta, Osama Ismail Zaid, Ahmed Shaker Ragab, Ahmed Essam Salem, Badawy Mohamed AlKholy
BACKGROUND: Patients undergoing craniotomy operations are prone to various noxious stimuli, many strategies are commenced to provide state of analgesia, for better control of the stress response and to overcome its undesired effects on the haemodynamics and post-operative pain. Scalp nerves block are considered one of these strategies. This study was conceived to evaluate the effect of addition of hyaluronidase to the local anaesthetic mixture used in the scalp nerves block in patients undergoing elective craniotomy operations...
September 15, 2018: BMC Anesthesiology
George Ho, Crispiana Cozowicz, Jean Wong, Mandeep Singh, Enoch Lam, Eva E Mörwald, Najia Hasan, Stavros G Memtsoudis, Frances Chung
BACKGROUND: Screening and optimizing patients for OSA in the perioperative period may reduce postoperative complications. However, sleep studies can be difficult to obtain before surgery. Previous surveys reported that the majority of sleep physicians would delay surgery to diagnose and manage OSA, but most anesthesiologists would not. While disagreements exist, the importance of shared decision making and patient preferences have never been studied on this topic. It is unknown whether patients with suspected OSA, when given information about OSA, would be willing to delay surgery to diagnose and manage their condition preoperatively...
September 12, 2018: BMC Anesthesiology
Chu-Lian Gong, Jing-Ping Hu, Zhuo-Lin Qiu, Qian-Qian Zhu, Zi-Qing Hei, Shao-Li Zhou, Xiang Li
BACKGROUND: The present survey evaluated the incidence of perioperative cardiac arrests in a Chinese tertiary general teaching hospital over ten years. METHODS: The incidence of cardiac arrest that occurred within 24 h of anaesthesia administration was retrospectively identified in the Third Affiliated Hospital of Sun Yat-Sen University between August 2007 and October 2017. Overall, 152,513 anaesthetics were included in the study period. Data collected included patient characteristics, American Society of Anaesthesiologists (ASA) physical status score, surgical specialty and anaesthesia technique...
September 11, 2018: BMC Anesthesiology
Jie Yi, Hao Liang, Ruiyue Song, Hailu Xia, Yuguang Huang
BACKGROUND: Inadvertent intraoperative hypothermia (core temperature < 36 °C) is a common but preventable adverse event. This study aimed to determine whether active intraoperative warming reduced bleeding in patients undergoing major operations: open thoracic surgery and hip replacement surgery. METHODS/DESIGN: The study was a pilot, prospective, parallel two-arm randomized controlled trial. Eligible patients were randomly allocated to two groups: passive warming (PW), with application of a cotton blanket (thermal insulation), or active warming (AW), with a forced-air warming system...
September 8, 2018: BMC Anesthesiology
RyungA Kang, Byung Seop Shin, Young Hee Shin, Nam-Su Gil, Ye Na Oh, Ji Seon Jeong
BACKGROUND: Propofol is an excellent hypnotic drug for use in repeated radiation procedures in young children. To date, tolerance to propofol generally does not develop in pediatric patients undergoing radiation therapy. However, several studies have suggested that there may be potential for development of tolerance to propofol. The aim of this study was to evaluate the development of a tolerance to propofol used for repeated deep sedation in children undergoing proton radiation therapy (PRT)...
September 7, 2018: BMC Anesthesiology
Youssef Ezhar, Frederick D'Aragon, Pablo Echave
BACKGROUND: Direct laryngoscopy (DL) produce tachycardia and hypertension that could be fatal in a patient with a brain injury. Bonfils fiberscope and C-MAC videolaryngoscope are associated with little hemodynamic instability compared to DL. Scientific evidence comparing these two alternatives does not exist. We conducted this study to determine the hemodynamic effects of Bonfils compared to C-MAC in patients undergoing elective surgery. METHODS: Fifty (50) patients listed for elective surgery were randomly assigned to endotracheal intubation with Bonfils or C-MAC...
September 7, 2018: BMC Anesthesiology
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