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BMC Ophthalmology

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https://www.readbyqxmd.com/read/28645328/ocular-manifestations-as-first-signs-of-systemic-t-cell-lymphoma-in-two-cases
#1
Xiao Zhang, Xin-Shu Liu, Chan Zhao, Ya-Min Lai, Mei-Fen Zhang
BACKGROUND: Intraocular involvement of systemic T-cell lymphomas are uncommon and have been broadly regarded as markers of poor prognosis. We reported two cases of uveitis patients finally diagnosed as systemic T cell lymphoma. CASE PRESENTATION: Case one is a 19-year-old female presented with fever and liver dysfunction, and was diagnosed as EBV-associated chronic active hepatitis. Fourteen months later, she suffered from recurrent granulomatous anterior uveitis in both eyes, which failed to respond to steroid and immunosuppressant therapy...
June 23, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28645265/a-pilot-study-lasek-with-the-triple-a-profile-of-a-mel-90-for-mild-and-moderate-myopia
#2
Yingjun Chen, Dong Yang, Tian Han, Haipeng Xu, Meiyan Li, Xingtao Zhou
BACKGROUND: To investigate the visual and refractive outcomes in patients with mild to moderate myopia after laser-assisted subepithelial keratectomy (LASEK) using the 500 Hz pulse rate of the Triple-A profile. METHODS: Thirty-six eyes of 20 patients (mean age, 27.5 ± 4.6 years) were included in this prospective, consecutive study. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), corneal topography, and corneal aberrations were measured preoperatively and 1 day, 1 week, 1, 3 and 6 months post-operation...
June 23, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28637435/association-between-polymorphism-rs11200638-in-the-htra1-gene-and-the-response-to-anti-vegf-treatment-of-exudative-amd-a-meta-analysis
#3
Ya-Li Zhou, Chun-Li Chen, Yi-Xiao Wang, Yao Tong, Xiao-Ling Fang, Lin Li, Zhao-Yang Wang
BACKGROUND: Anti-angiogenesis treatments are the most commonly used treatments for the vision loss caused by exudative age-related macular degeneration (AMD), in which the anti-vascular endothelial growth factor (VEGF) drugs with ranibizumab and bevacizumab are current standard treatments. However, the outcome of anti-VEGF therapeutics is not uniform in all patients. METHODS: We performed a literature-based meta-analysis including, five published studies relevant to HTRA1 and response to anti-VEGF treatment (bevacizumab or ranibizumab)...
June 21, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28629400/characteristics-of-syphilitic-uveitis-in-northern-china
#4
Xiaomin Zhang, Qian Du, Feifei Ma, Yinglong Lu, Meiyan Wang, Xiaorong Li
BACKGROUND: To describe the characteristics of patients with syphilitic uveitis in northern China. METHODS: A case series of 21 patients (33 eyes) diagnosed with syphilitic uveitis from 2011 to 2016 at a tertiary center in northern China was retrospectively analyzed. RESULTS: Twenty-one patients (33 eyes) were diagnosed as syphilitic uveitis. Posterior segment involvement was found in 32 eyes (97.0%). Vitreous haze, neuroretinitis, and posterior placoid chorioretinitis were mainly found in patients with a relatively short duration of the disease, while diffuse chorioretinitis, pseudoretinitis pigmentosa, cystoid macular edema, and epiretinal membrane were found in patients with relatively long duration of ocular involvement...
June 19, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28629391/anterior-lens-capsule-and-epithelium-thickness-measurements-using-spectral-domain-optical-coherence-tomography
#5
Jing Dong, Yading Jia, Yaqin Zhang, Haining Zhang, Zhijie Jia, Suhua Zhang, Qiang Wu, Qingmao Hu, Tianqiao Zhang, Xiaogang Wang
BACKGROUND: To investigate the anterior lens capsule and epithelium thickness (defined as anterior lens capsular complex: ALCC) in normal Chinese subjects using spectral-domian optical coherence tomography (SD-OCT) and examine the factors that may influence the ALCC, such as age, gender, pupil diameter (PD) and signal strength index (SSI). METHODS: A prospective observational case series. One-hundred-thirty-four normal subjects (134 eyes) were included. The ALCCs were determined manually via SD-OCT...
June 19, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28629328/impact-of-systematic-capacity-building-on-cataract-surgical-service-development-in-25-hospitals
#6
Katherine Judson, Paul Courtright, Thulsiraj Ravilla, Rohit Khanna, Ken Bassett
BACKGROUND: This study measured the effectiveness and cost of a capacity building intervention in 25 eye hospitals in South Asia, East Africa and Latin America over 4 years. The intervention involved eye care non-governmental organizations or high-performing eye hospitals acting as "mentors" to underperforming eye hospitals- "mentees" in 10 countries. Intervention activities included systematic planning and support for training and key equipment purchases as well as hospital-specific mentoring which focused on strengthening leadership, increasing the volume and equity of community outreach, improving surgical quality and volume, strengthening organizational and financial management and streamlining operational processes...
June 19, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28619056/ophthalmic-artery-occlusion-following-neuro-embolization-of-the-external-carotid-artery-a-case-report
#7
Ng Wei Loon, Balwant Singh Gendeh, Rozman Zakaria, Jemaima Che Hamzah, Norshamsiah Md Din
BACKGROUND: Embozene® is a new neuroembolizing microsphere used to reduce intraoperative bleeding for head and neck tumours. We report a case of iatrogenic ophthalmic artery occlusion after Embozene® embolization of the external carotid artery (ECA). CASE PRESENTATION: A 22-year-old African gentleman presented with left nasal obstruction and epistaxis for 2 years and was diagnosed with nasopharyngeal carcinoma. He subsequently underwent embolization of the maxillary branch of the left ECA using Embozene® Microspheres - 250 μm in size before endoscopic tumour excision to reduce intra-operative bleeding...
June 15, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28619029/rapid-deterioration-of-mooren-s-ulcers-after-conjunctival-flap-a-review-of-2-cases
#8
Saiqun Li, Yuqing Deng, Caiyuan Du, Haixiang Huang, Jing Zhong, Ling Chen, Bowen Wang, Jin Yuan
BACKGROUND: Conjunctival flaps are a widely used treatment for numerous corneal ulcers that are caused by microorganismal infections. However, whether it can be performed on immune-mediated corneal ulcers is controversial. CASE PRESENTATION: We present two cases of Mooren's ulcer that were treated using conjunctival flap in an attempt to prevent further corneal perforation at their local hospital. A rapid acceleration in ulcer progression was observed after a conjunctival flap was applied...
June 15, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28615013/short-term-poor-glycemic-control-and-retinal-microvascular-changes-in-pediatric-type-1-diabetes-patients-in-singapore-a-pilot-study
#9
Ling-Jun Li, Ecosse Lamoureux, Tien Yin Wong, Ngee Lek
BACKGROUND: Poor glycemic control in Type 1 Diabetes (T1D) patients is strongly associated with an increased risk of diabetes-related microvascular complications later in life, but it is unclear whether short period of poor glycemic control in children with T1D can cause evident microvascular morphological changes long before any pathological manifestation. Our study aimed to investigate the longitudinal association between poor glycemic control and subsequent changes in retinal microvasculature, in a pilot study of 55 pediatric T1D patients from Singapore after a one-year follow-up...
June 15, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28615022/correlation-of-retinal-nerve-fibre-layer-and-macular-thickness-with-serum-uric-acid-among-type-2-diabetes-mellitus
#10
Munisamy-Naidu Vinuthinee-Naidu, Embong Zunaina, Anuar Azreen-Redzal, Naing Nyi-Nyi
BACKGROUND: Uric acid is a final breakdown product of purine catabolism in humans. It's a potent antioxidant and can also act as a pro-oxidant that induces oxidative stress on the vascular endothelial cells, thus mediating progression of diabetic related diseases. Various epidemiological and experimental evidence suggest that uric acid has a role in the etiology of type 2 diabetes mellitus. We conducted a cross-sectional study to evaluate the correlation of retinal nerve fibre layer (RNFL) and macular thickness with serum uric acid in type 2 diabetic patients...
June 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28610611/telemedicine-screening-of-retinal-diseases-with-a-handheld-portable-non-mydriatic-fundus-camera
#11
Kai Jin, Haitong Lu, Zhaoan Su, Chuming Cheng, Juan Ye, Dahong Qian
BACKGROUND: We modified and reconstructed a high image quality portable non-mydriatic fundus camera and compared it with the tabletop fundus camera to evaluate the efficacy of the new camera in detecting retinal diseases. METHODS: We designed and built a novel portable handheld fundus camera with telemedicine system. The image quality of fundus cameras was compared to that of existing commercial tabletop cameras by taking photographs of 364 eyes from the 254 patients...
June 13, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28610573/correlation-between-short-and-long-term-effects-of-intravitreal-ranibizumab-therapy-on-macular-edema-after-branch-retinal-vein-occlusion-a-prospective-observational-study
#12
Yoshiro Minami, Taiji Nagaoka, Akihiro Ishibazawa, Akitoshi Yoshida
BACKGROUND: The correlation between the short- and long-term effects of intravitreal ranibizumab (IVR) on macular edema after branch retinal vein occlusion (BRVO) remains unclear. We assessed the correlation between the short- and long-term effects of IVR on macular edema after BRVO. METHODS: Twenty-one eyes with macular edema after BRVO were enrolled in this prospective observational study. We measured the foveal thickness (FT) and the best-corrected visual acuity (BCVA) before, 1 day after, and 1 month after IVR (0...
June 13, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28606071/the-increasing-prevalence-of-myopia-in-junior-high-school-students-in-the-haidian-district-of-beijing-china-a-10-year-population-based-survey
#13
Yan Li, Jia Liu, Pengcheng Qi
BACKGROUND: Myopia is a leading cause of preventable blindness. Although, multiple cross-sectional epidemiological studies have confirmed that there is a high prevalence of myopia in high school-aged students in China. However, few longitudinal studies have been performed to assess junior high school students. In the present study, we investigate changes in the prevalence of myopia in third year junior high school (grade 9) students in the Haidian District of Beijing, China, from 2006 to 2015...
June 12, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28606070/efficacy-and-safety-of-conbercept-as-a-primary-treatment-for-choroidal-neovascularization-secondary-to-punctate-inner-choroidopathy
#14
Yuting Peng, Xiongze Zhang, Lan Mi, Bing Liu, Chengguo Zuo, Miaoling Li, Feng Wen
BACKGROUND: To evaluate the efficacy and safety of intravitreal conbercept (KH902) as the primary treatment of choroidal neovascularization secondary to punctate inner choroidopathy. METHODS: This study was a retrospective, consecutive, observational case series. We reviewed medical records of 16 eyes (16 patients) with naive subfoveal or juxtafoveal choroidal neovascularization secondary to punctuate inner choroidopathy that were treated with intravitreal conbercept injections...
June 12, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28595625/blood-flow-velocity-and-thickness-of-the-choroid-in-a-patient-with-chorioretinopathy-associated-with-ocular-blunt-trauma
#15
Yuri Ishikawa, Yuki Hashimoto, Wataru Saito, Ryo Ando, Susumu Ishida
BACKGROUND: Choroidal circulation hemodynamics in eyes with ocular blunt trauma has not been quantitatively examined yet. We quantitatively examined changes in choroidal blood flow velocity and thickness at the lesion site using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical coherence tomography (EDI-OCT) in a patient with chorioretinopathy associated with ocular blunt trauma. CASE PRESENTATION: A 13-year-old boy developed a chorioretinal lesion with pigmentation extending from the optic disc to the superotemporal side in the right eye after ocular blunt trauma...
June 8, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28592279/the-effect-of-post-traumatic-stress-disorder-on-intra-operative-analgesia-in-a-veteran-population-during-cataract-procedures-carried-out-using-retrobulbar-or-topical-anesthesia-a-retrospective-study
#16
Yuna Rapoport, Laura L Wayman, Amy S Chomsky
BACKGROUND: A growing proportion of veterans treated at the Veterans Health Administration (VA) have a history of post-traumatic-stress-disorder (PTSD), and there exists a higher rate of PTSD amongst veterans than the general population. The purpose of this study is to determine the correlation between PTSD and intra-operative analgesia, intra-operative time, and anesthesia type for cataract surgery in a veteran population. Secondary objectives are to determine if patient age, and first or second eye surgery affect intra-operative pain control or are correlated with type of anesthesia modality...
June 7, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28592257/clinical-safety-and-efficacy-of-vitamin-d3-analog-ointment-for-treatment-of-obstructive-meibomian-gland-dysfunction
#17
Reiko Arita, Motoko Kawashima, Masataka Ito, Kazuo Tsubota
BACKGROUND: Hyperkeratinization is a major cause of obstructive meibomian gland dysfunction (oMGD) and results in degenerative gland dilation and atrophy without inflammation. Ointment containing 1,25-dihydroxy-22-oxavitamin D3 (maxacalcitol), a noncalcemic analog of the active form of vitamin D3, is applied for the treatment of hyperkeratotic cutaneous conditions such as psoriasis and ichtyosis because it suppresses the proliferation and promotes the differentiation of keratinocytes through interaction with the vitamin D receptor...
June 7, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28578676/effects-of-optical-diameter-of-intraocular-lenses-with-intrascleral-fixation-on-higher-order-aberrations
#18
Daisuke Kunita, Makoto Inoue, Yuji Itoh, Naoko Matsuki, Toshiyuki Nagamoto, Akito Hirakata
BACKGROUND: Intrascleral fixation of an intraocular lens (IOL) is used in eyes that lack capsular support. The aim of the study is to determine whether a larger optical diameter IOL will decrease the higher-order aberrations (HOAs) when the haptics are extended for intrascleral fixation than a smaller diameter IOL. METHODS: Three-piece acrylic IOLs with 6.0 mm optics (X-60, VA-60BBR) and 7.0 mm optics (X-70, VA-70 AD) were fixed at lengths of 13, 14, 15, 16, or 17 mm...
June 2, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28577362/serum-uric-acid-concentration-is-associated-with-hypertensive-retinopathy-in-hypertensive-chinese-adults
#19
Xuling Chen, Ying Meng, Jun Li, Hiacheng She, Liang Zhao, Jing Zhang, Yuan Peng, Kun Shang, Yadi Zhang, Xiaopeng Gu, Wenbin Yang, Yan Zhang, Jianping Li, Xianhui Qin, Binyan Wang, Xiping Xu, Fanfan Hou, Genfu Tang, Rongfeng Liao, Yong Huo, Liu Yang
BACKGROUND: This cross sectional investigation included 12,966 subjects with hypertension, a cohort of the China Stroke Primary Prevention Trial (CSPPT), a randomized, multicenter clinical trial. This study aimed to explore the correlation between serum uric acid (SUA) concentration and hypertensive retinopathy in hypertensive adults. METHODS: Diagnosis of hypertensive retinopathy was determined by non-mydriatic fundus photography and classified with Keith-Wagener-Barker (KWB) system...
June 2, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28558665/the-association-between-genetic-polymorphisms-of-the-interleukin-23-receptor-gene-and-susceptibility-to-uveitis-a-meta-analysis
#20
Jae Hyun Jung, Gwan Gyu Song, Jae-Hoon Kim, Young Ho Seo, Sung Jae Choi
BACKGROUND: Uveitis is an eye inflammatory disease, which is sometimes associated with underlying systemic disease. Interleukin-23 plays an important role in autoimmune disease. The aim of this meta-analysis was to evaluate the association between the interleukin-23 receptor (IL-23R) and susceptibility to uveitis. METHODS: Published literature from PUBMED and EMBASE were retrieved. Seven studies were included in this meta-analysis, covering a total of 1309 cases of uveitis and 2400 controls...
May 30, 2017: BMC Ophthalmology
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