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BMC Ophthalmology

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https://www.readbyqxmd.com/read/29784048/a-meta-analysis-of-the-effect-of-a-dexamethasone-intravitreal-implant-versus-intravitreal-anti-vascular-endothelial-growth-factor-treatment-for-diabetic-macular-edema
#1
Ye He, Xin-Jun Ren, Bo-Jie Hu, Wai-Ching Lam, Xiao-Rong Li
BACKGROUND: This meta-analysis evaluated the effectiveness and safety of dexamethasone (DEX) implant and intravitreal anti-vascular endothelial growth factor (VEGF) treatment for diabetic macular edema (DME). METHODS: The PubMed, Embase, clinicaltrials.gov website and Cochrane Library databases were comprehensively searched for studies comparing DEX implant with anti-VEGF in patients with DME. Best-corrected visual acuity (BCVA), central subfield thickness (CST) and adverse events were extracted from the final eligible studies...
May 21, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29776352/surgical-peripheral-iridectomy-via-a-clear-cornea-phacoemulsification-incision-for-pupillary-block-following-cataract-surgery-in-acute-angle-closure
#2
Aiwu Fang, Peijuan Wang, Rui He, Jia Qu
BACKGROUND: To describe a technique of surgical peripheral iridectomy via a clear-cornea tunnel incision to prevent or treat pupillary block following phacoemulsification. METHODS: Description of technique and retrospective description results in 20 eyes of 20 patients with acute angle closure with coexisting visually significant cataract undergoing phacoemulsification considered at risk of postoperative papillary block as well as two pseudo-phakic eyes with acute postoperative pupillary-block...
May 18, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29764389/comparison-of-hyperdry-amniotic-membrane-transplantation-and-conjunctival-autografting-for-primary-pterygium
#3
Xin Pan, Daguang Zhang, Zhifang Jia, Zhehui Chen, Yuetian Su
BACKGROUND: The purpose of this study was to evaluate the safety and effectiveness of the hyperdry amniotic membrane transplantation compared with conjunctival autografting for the treatment of primary pterygium. METHODS: One hundred and forty-one eyes from 130 patients with primary pterygium were treated with excision followed by hyperdry amniotic membrane or conjunctival autografting after random selection. Seventy-nine eyes from 71 patients received hyperdry amniotic membrane transplantation (HD-AM group), and 62 eyes from 59 patients received conjunctival autografting (CG group)...
May 15, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29747615/prevalence-of-refractive-errors-in-tibetan-adolescents
#4
Xuehan Qian, Beihong Liu, Jing Wang, Nan Wei, Xiaoli Qi, Xue Li, Jing Li, Ying Zhang, Ning Hua, Yuxian Ning, Gang Ding, Xu Ma, Binbin Wang
BACKGROUND: The prevalence of adolescent eye disease in remote areas of the Qinghai-Tibet Plateau has rarely been reported. To understand the prevalence of common eye diseases in Tibet, we performed ocular-disease screening on students from primary and secondary schools in Tibet, and compared the prevalence to that in the Central China Plain (referred to here as the "plains area"). METHODS: The refractive status of students was evaluated with a Spot™ vision screener...
May 11, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29747621/prevalence-and-clinical-characteristics-of-dry-eye-disease-in-community-based-type-2-diabetic-patients-the-beixinjing-eye-study
#5
Xinrong Zou, Lina Lu, Yi Xu, Jianfeng Zhu, Jiangnan He, Bo Zhang, Haidong Zou
BACKGROUND: This study was performed to evaluate the prevalence and clinical characteristics of dry eye disease (DED) in community-based type 2 diabetic patients and to identify the associated factors related with DED. METHODS: A total of 1360 type 2 diabetic patients in the Beixinjing community were randomly selected. All participants were given a questionnaire that assessed basic information and subjective symptoms.DED was diagnosed using the revised Japanese DED diagnostic criteria...
May 10, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29747619/clinical-results-of-the-open-ring-pmma-guider-assisted-capsulorrhexis-in-cataract-surgery
#6
Jee Hye Lee, Yong Eun Lee, Choun-Ki Joo
BACKGROUND: To compare the results of continuous curvilinear capsulorrhexis(CCC) after application of an open ring-shaped guider compared with a free-hand procedure in eyes with cataracts. METHODS: This study comprised patients undergoing cataract surgery in Seoul St.Mary's Hospital, The Catholic University of Korea. Eyes were grouped depending on the capsulotomy method; CCC was performed by free-hand procedure on 94 eyes (free-hand group), and it was performed under the guidance after introduction of an open ring-shaped guider on consecutive 89 eyes (guided group)...
May 10, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29743110/analysis-of-intraocular-positions-of-posterior-implantable-collamer-lens-by-full-scale-ultrasound-biomicroscopy
#7
Xi Zhang, Xun Chen, Xiaoying Wang, Fei Yuan, Xingtao Zhou
BACKGROUND: To analyze the positions of intraocular posterior Implantable Collamer Lens (ICL) and its possible relationship with vault. METHODS: This cross-sectional study included 72 patients with high myopia (134 eyes) who were followed up after phakic intraocular lens implantation. The postoperative time ranged from 1 week to 7 years. We obtained the images of ICL by using Compact Touch STS UBM and observed the position of ICL in posterior chamber and ciliary sulcus...
May 9, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29743044/clinical-outcomes-of-transepithelial-photorefractive-keratectomy-to-treat-low-to-moderate-myopic-astigmatism
#8
Lei Xi, Chen Zhang, Yanling He
BACKGROUND: To evaluate the refractive and visual outcomes of Transepithelial photorefractive keratectomy (TransPRK) in the treatment of low to moderate myopic astigmatism. METHODS: This retrospective study enrolled a total of 47 eyes that had undergone Transepithelial photorefractive keratectomy. Preoperative cylinder diopters ranged from - 0.75D to - 2.25D (mean - 1.11 ± 0.40D), and the sphere was between - 1.50D to - 5.75D. Visual outcomes and vector analysis of astigmatism that included error ratio (ER), correction ratio (CR), error of magnitude (EM) and error of angle (EA) were evaluated...
May 9, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29739379/assessment-of-capillary-dropout-in-the-superficial-retinal-capillary-plexus-by-optical-coherence-tomography-angiography-in-the-early-stage-of-diabetic-retinopathy
#9
Ceying Shen, Shu Yan, Min Du, Hong Zhao, Ling Shao, Yibo Hu
BACKGROUND: To assess capillary dropout in the superficial retinal capillary plexus (SCP) by optical coherence tomography angiography (OCTA) in the early stage of diabetic retinopathy (DR). METHODS: This study was a cross-sectional observational study. Patients that underwent OCTA examinations in our hospital between November 2015 and May 2016 were included in the study. The subjects were divided into two groups: A) normal controls (41 eyes of 41 subjects) and B) the DR patients (49 eyes of 49 patients with mild non-proliferative DR (NPDR))...
May 8, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29724209/microbial-keratitis-induced-endophthalmitis-incidence-symptoms-therapy-visual-prognosis-and-outcomes
#10
Daniel Zapp, Daria Loos, Nikolaus Feucht, Ramin Khoramnia, Tamer Tandogan, Lukas Reznicek, Christian Mayer
BACKGROUND: To evaluate symptoms, therapies and outcomes in rare microbial keratitis-induced endophthalmitis. METHODS: Retrospective study with 11 patients treated between 2009 and 2014. Clinical findings, corneal diseases, history of steroids and trauma, use of contact lenses, number and type of surgical interventions, determination of causative organisms and visual acuity (VA) were evaluated. RESULTS: The incidence of transformation from microbial keratitis to an endophthalmitis was 0...
May 3, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29720128/the-efficacy-of-viscocanalostomies-and-combined-phacoemulsification-with-viscocanalostomies-in-the-treatment-of-patients-with-glaucoma-a-non-randomised-observational-study
#11
Andrew Want, Derek K-H Ho, Bhavani Karri, Divya Mathews
BACKGROUND: To evaluate the outcomes of Viscocanalostomy (VC) and Phacoviscocanalostomy (PV) in controlling primary and secondary glaucoma in a large cohort of patients from a single eye unit and performed by a single surgeon. METHODS: This non-randomised, retrospective study was conducted on 620 eyes of 458 patients. All patients who had either viscocanalostomy (VC) or combined phacoemulsification and viscocanalostomy (PV) over a three-year period were included...
May 2, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29703256/manipulation-of-autophagy-a-novelly-potential-therapeutic-strategy-for-retinal-neovascularization
#12
Rong Li, Jin Tian, Junhui Du, Lei Zhao, Yang Yao, Zhaoxiang Yu, Weiping Chang, Rui Shi, Jing Li
BACKGROUND: The relationship between the role of VEGF and autophagy in the process of retinal angiogenesis is still unclear. In this study, we explored this issue by using the mouse retinal vascular endothelial cell (RVEC) as a model. METHODS: RVECs were divided into the following groups: control, hypoxia (H), 3-methyladenine (3-MA) + H, VEGF + H, 3-MA + VEGF+H, anti-VEGF antibody + H, 3-MA+ anti-VEGF antibody + H. We then examined activation of autophagy by detecting formation of autophagosomes with transmission electron microscopy (TEM) and by counting the number of green fluorescent protein-positive (GFP+) puncta in RVECs...
April 27, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29699518/comparison-of-two-techniques-for-toric-intraocular-lens-implantation-hydroimplantation-versus-ophthalmic-viscosurgical-devices
#13
Yueqin Chen, Qian Cao, Chunyan Xue, Zhenping Huang
BACKGROUND: To compare the results between hydroimplantation of a single-piece, acrylic foldable toric intraocular lens (IOLs) and conventional implantation using an ophthalmic viscosurgical device (OVD). METHODS: In this study, 60 eyes with cataract and preexisting regular corneal astigmatism of 1.0 to 3.0 diopters (D) underwent the implantation of the AcrySof toric IOLs (Alcon Laboratories, Inc.). The patients were randomly assigned to a conventional implantation technique with an OVD or a hydroimplantation technique...
April 24, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29688848/combined-23-gauge-transconjunctival-vitrectomy-and-scleral-fixation-of-intraocular-lens-without-conjunctival-dissection-in-managing-lens-complications
#14
Ling Yeung, Nan-Kai Wang, Wei-Chi Wu, Kuan-Jen Chen
BACKGROUND: To evaluate the safety and efficacy of combined 23-gauge transconjunctival pars plana vitrectomy and scleral fixation of intraocular lens (IOL) without conjunctival dissection. METHODS: A retrospective study in Chang Gung Memorial Hospital, Keelung and Taoyuan, Taiwan. Patients receiving combined 23-gauge transconjunctival pars plana vitrectomy and scleral fixation of IOL without conjunctival dissection were enrolled. The ocular findings, causes of lens complication, surgical procedures, type of IOL used, and complications were documented...
April 23, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29685130/cataract-surgery-in-patients-with-corneal-opacities
#15
Yi-Ju Ho, Chi-Chin Sun, Hung-Chi Chen
BACKGROUND: Investigating the efficacy and safety of phacoemulsification with intraocular lens (IOL) implantation in corneal opacities. METHODS: This retrospective study was conducted in a tertiary medical center. Twenty-three eyes of 19 patients with cataracts and corneal opacities obscuring the pupillary center having received phacoemulsification with IOL insertion without any ancillary techniques were enrolled. The primary study outcome measures were uncorrected and best corrected visual acuity (BCVA), and complications...
April 23, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29685116/characterization-treatment-and-prognosis-of-retinoblastoma-with-central-nervous-system-metastasis
#16
Huimin Hu, Weiling Zhang, Yizhuo Wang, Dongsheng Huang, Jitong Shi, Bin Li, Yi Zhang, Yan Zhou
BACKGROUND: Retinoblastoma is the most common primary intraocular tumor and more and more attention has been paid to the developing countries. This study was aimed to evaluate the clinical features, treatment, and prognosis of retinoblastoma patients with central nervous system (CNS) metastasis in Beijing Tongren Hospital, one of the largest tertiary eye centers in China. METHODS: Clinical data of 31 consecutive retinoblastoma patients with CNS metastases, who were diagnosed at the Department of Pediatrics in Beijing Tongren Hospital between September 2005 and December 2015, were retrospective analyzed...
April 23, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29673332/expression-of-cytokines-in-aqueous-humor-from-fungal-keratitis-patients
#17
Yingnan Zhang, Qingfeng Liang, Yang Liu, Zhiqiang Pan, Christophe Baudouin, Antoine Labbé, Qingxian Lu
BACKGROUND: Although a series of reports on corneal fungal infection have been published, studies on pathogenic mechanisms and inflammation-associated cytokines remain limited. In this study, aqueous humor samples from fungal keratitis patients were collected to examine cytokine patterns and cellular profile for the pathogenesis of fungal keratitis. METHODS: The aqueous humor samples were collected from ten patients with advanced stage fungal keratitis. Eight aqueous humor samples from patients with keratoconus or corneal dystrophy were taken as control...
April 19, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29673326/surgical-factors-affecting-oculocardiac-reflex-during-strabismus-surgery
#18
Suk-Gyu Ha, Jungah Huh, Bo-Ram Lee, Seung-Hyun Kim
BACKGROUND: To investigate surgical factors associated with the occurrence of oculocardiac reflex (OCR) and changes in heart rate (HR) during strabismus surgery. METHODS: Patients who underwent strabismus surgery under general anesthesia were enrolled in this study. The HR during surgery was measured at baseline, and at the following points during surgery: traction of the muscle, maximal increase after traction (adrenergic phase), and the cutting of the muscle. OCR was defined as an HR reduction of more than 20% at traction of the muscle, when compared to baseline HR...
April 19, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29673317/budget-impact-model-of-mydrane%C3%A2-a-new-intracameral-injectable-used-for-intra-operative-mydriasis-from-a-uk-hospital-perspective
#19
Keith Davey, Bernard Chang, Christine Purslow, Emilie Clay, Anne-Lise Vataire
BACKGROUND: During cataract surgery, maintaining an adequate degree of mydriasis throughout the entire operation is critical to allow for visualisation of the capsulorhexis and the crystalline lens. Good anaesthesia is also essential for safe intraocular surgery. Mydrane® is a new injectable intracameral solution containing two mydriatics (tropicamide 0.02% and phenylephrine 0.31%) and one anaesthetic (lidocaine 1%) that was developed as an alternative to the conventional topical pre-operative mydriatics used in cataract surgery...
April 19, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29669533/general-analysis-of-factors-influencing-cataract-surgery-practice-in-shanghai-residents
#20
Yi Xu, Jiangnan He, Senlin Lin, Bo Zhang, Jianfeng Zhu, Serge Resnikoff, Lina Lu, Haidong Zou
BACKGROUND: It was reported that lack of knowledge, less confidence of medical services, commute difficulties, and poor economic conditions would be the main barriers for cataract surgery practice. The influencing factors could have changed in cities with high developing speed. Shanghai is one of the biggest cities in China and the world. The purpose of the study was to explore the factors influencing cataract surgery practice in Shanghai. METHODS: This was a population-based, cross-sectional study...
April 18, 2018: BMC Ophthalmology
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