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BMC Ophthalmology

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https://www.readbyqxmd.com/read/28335747/effects-of-diurnal-lighting-and-angle-of-incidence-variation-on-anterior-segment-optical-coherence-tomography-as-oct-angle-metrics
#1
Handan Akil, Anna Dastiridou, Kenneth Marion, Brian A Francis, Vikas Chopra
BACKGROUND: First reported study to assess the effect of diurnal variation on anterior chamber angle measurements, as well as, to re-test the effects of lighting and angle-of-incidence variation on anterior chamber angle (ACA) measurements acquired by time-domain anterior segment optical coherence tomography (AS-OCT). METHODS: A total of 30 eyes from 15 healthy, normal subjects underwent anterior chamber imaging using a Visante time-domain AS-OCT according to an IRB-approved protocol...
March 23, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28327135/stratification-of-phaco-trabectome-surgery-results-using-a-glaucoma-severity-index-in-a-retrospective-analysis
#2
Pritha Roy, Ralitsa T Loewen, Yalong Dang, Hardik A Parikh, Igor I Bussel, Nils A Loewen
BACKGROUND: To stratify the outcomes of phacoemulsification combined with trabectome surgery using a new glaucoma severity index. METHODS: This is a retrospective, observational cohort study that included open angle glaucoma patients with visually significant cataract that had phacoemulsification combined with trabectome surgery. Exclusion criteria were follow-up less than 12 months, any other surgeries or diagnosis of neovascular or active uveitic glaucoma. Patients were stratified into four groups according to the Glaucoma Index (GI) that incorporated preoperative intraocular pressure (IOP), number of medications and visual field status...
March 21, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28302098/in-vivo-confocal-microscopy-of-pre-descemet-corneal-dystrophy-associated-with-x-linked-ichthyosis-a-case-report
#3
Hui Shi, Xiao-Feng Qi, Tao-Tao Liu, Qian Hao, Xiao-Hong Li, Ling-Ling Liang, Yi-Miao Wang, Zhi-Hua Cui
BACKGROUND: Pre-Descemet corneal dystrophy (PDCD) is characterized by the presence of numerous, tiny, polymorphic opacities immediately anterior to Descemet membrane, which is a rare form of corneal stromal dystrophy and hard to be diagnosed. In vivo confocal microscopy (IVCM) is a useful tool to examine the minimal lesions of the cornea at the cellular level. In this article, we report a rare case of PDCD associated with X-linked ichthyosis and evaluate IVCM findings. CASE PRESENTATION: We present a 34-year-old male Chinese patient with PDCD associated with X-linked ichthyosis...
March 16, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28292276/effect-of-modified-graded-recession-and-anteriorization-on-unilateral-superior-oblique-palsy-a-retrospective-study
#4
Dong Cheol Lee, Se Youp Lee
BACKGROUND: Several inferior oblique (IO) weakening methods exist for correction of superior oblique palsy (SOP). A previously reported method involved recession and anteriorization according to IO overaction (IOOA) grade, which might be subjective and cause upgaze limitation and opposite vertical strabismus. Therefore, this study attempted to examine the efficacy of modified graded recession and anteriorization of the IO muscle in correction of unilateral SOP without resulting in upgaze limitation or opposite vertical strabismus...
March 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28292270/short-term-effects-of-intravitreal-ranibizumab-therapy-on-diabetic-macular-edema
#5
Yoshiro Minami, Taiji Nagaoka, Akihiro Ishibazawa, Akitoshi Yoshida
BACKGROUND: The short-term effects of intravitreal ranibizumab (IVR) on diabetic macular edema (DME) remains unclear. We assessed the short-term effects of IVR on DME. METHODS: Eighteen eyes of 14 patients with DME were enrolled in this prospective interventional case series. After intravitreal ranibizumab was injected into treatment-naïve eyes with DME, we measured the foveal thickness (FT) before and 2 h, 1 day, 1 week, and 1 month later and the best-corrected visual acuity (BCVA) at all times except 2 h and compared the changes to baseline (ΔFT and ΔVA)...
March 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28288603/a-cute-angle-closure-attack-after-an-intravitreal-bevacizumab-injection-for-branch-retinal-vein-occlusion-a-case-report
#6
Seongyong Jeong, Min Sagong, Woohyok Chang
BACKGROUND: Intravitreal injection is widely used to treat retinal vein occlusion, and acute angle closure (AAC) is an exceptional complication of intravitreal injection. The authors report a case of AAC that occurred immediately after administering intravitreal bevacizumab to treat branch retinal vein occlusion (BRVO). CASE PRESENTATION: A 65-year-old woman was referred to the retina clinic of a tertiary referral center for the treatment of macular edema secondary to BRVO...
March 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28288590/iridoschisis-a-case-report-and-literature-review
#7
Yiyi Chen, Yiyong Qian, Peirong Lu
BACKGROUND: Iridoschisis is a rare condition that is characterized by the separation of the iris stroma into layers, with portions of the anterior layer floating freely in the aqueous humour. Here, we report three cases of iridoschisis that were complicated by either a cataract or glaucoma. Based on these cases, we speculate that the scope of iridoschisis has a rare association with intraocular pressure and the loss of corneal endothelial cells after surgery, which is mainly due to the surgery and not iridocorneal mechanical contact...
March 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28288589/choroidal-infarction-in-a-glaucoma-patient-with-flammer-syndrome-a-case-report-with-a-long-term-follow-up
#8
Barbara Terelak-Borys, Iwona Grabska-Liberek, Anita Piekarniak-Wozniak, Katarzyna Konieczka
BACKGROUND: We present a long term follow-up of a young female patient with choroidal infarction, primary open angle glaucoma and Flammer syndrome. The patient had no classical risk factors for vascular occlusions, except for the presence of Flammer syndrome. The essential feature of this syndrome is primary vascular dysregulation, sometimes including vasospasm. The vessels of affected people respond more intensely to a number of stimuli, such as coldness or emotional stress. Any organ can be involved, including parts of the eye...
March 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28288588/siderotic-cataract-with-no-signs-of-intraocular-foreign-body
#9
Ke-Ke Zhang, Wen-Wen He, Yi Lu, Xiang-Jia Zhu
BACKGROUND: Ocular siderosis is a clinical condition induced by deposition of an iron-containing intraocular foreign body. We report a unique case of histopathologically proven lens siderosis in a young woman with a preceding history of trauma but no signs of retained intraocular foreign body. CASE PRESENTATION: A 32-year-old woman presented with an opacified lens showing brownish deposits on the anterior capsule and underwent cataract surgery. Preoperative ophthalmic examination did not show any retained intraocular foreign body...
March 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28284199/unilateral-malignant-optic-glioma-following-glioblastoma-multiforme-in-the-young-a-case-report-and-literature-review
#10
Chia-Ying Lin, Hsiu-Mei Huang
BACKGROUND: Malignant optic gliomas are rare, but they rapidly become lethal visual pathway tumors. We present the clinical course, treatment, and prognosis of a case of unilateral malignant optic glioma in a young man with a history of brain glioblastoma multiforme (GBM). CASE PRESENTATION: A 21-year-old man, who had GBM 7 years ago complained of a transient shadow in his vision and presented with normal visual acuity but optic disc edema and an enlarged blind spot in the right eye (oculus dexter, OD)...
March 11, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28283025/ganglion-cell-inner-plexiform-layer-and-retinal-nerve-fiber-layer-thickness-according-to-myopia-and-optic-disc-area-a-quantitative-and-three-dimensional-analysis
#11
Sam Seo, Chong Eun Lee, Jae Hoon Jeong, Ki Ho Park, Dong Myung Kim, Jin Wook Jeoung
BACKGROUND: To determine the influences of myopia and optic disc size on ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (RNFL) thickness profiles obtained by spectral domain optical coherence tomography (OCT). METHODS: One hundred and sixty-eight eyes of 168 young myopic subjects were recruited and assigned to one of three groups according to their spherical equivalent (SE) values and optic disc area. All underwent Cirrus HD-OCT imaging...
March 11, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28270126/analysis-of-novel-sjogren-s-syndrome-autoantibodies-in-patients-with-dry-eyes
#12
Sandra Everett, Sahana Vishwanath, Vanessa Cavero, Long Shen, Lakshmanan Suresh, Kishore Malyavantham, Norah Lincoff-Cohen, Julian L Ambrus
BACKGROUND: Dry eye is a common problem in Ophthalmology and may occur for many reasons including Sjogren's syndrome (SS). Recent studies have identified autoantibodies, anti-salivary gland protein 1 (SP1), anti-carbonic anhydrase 6 (CA6) and anti-parotid secretory protein (PSP), which occur early in the course of SS. The current studies were designed to evaluate how many patients with idiopathic dry eye and no evidence of systemic diseases from a dry eye practice have these autoantibodies...
March 7, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28235399/case-report-of-an-atypical-early-onset-x-linked-retinoschisis-in-monozygotic-twins
#13
Vittoria Murro, Roberto Caputo, Giacomo Maria Bacci, Andrea Sodi, Dario Pasquale Mucciolo, Sara Bargiacchi, Sabrina Rita Giglio, Gianni Virgili, Stanislao Rizzo
BACKGROUND: X-linked Retinoschisis (XLRS) is one of the most common macular degenerations in young males, with a worldwide prevalence ranging from 1:5000 to 1:20000. Clinical diagnosis of XLRS can be challenging due to the highly variable phenotypic presentation and limited correlation has been identified between mutation type and disease severity or progression. CASE PRESENTATION: We report the atypical early onset of XLRS in 3-month-old monozygotic twins. Fundus examination was characterized by severe bullous retinal schisis with pre-retinal and intraretinal haemorrhages...
February 24, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28228121/bleb-failure-and-intraocular-pressure-rise-following-nd-yag-laser-capsulotomy
#14
Andreas Diagourtas, Petros Petrou, Ilias Georgalas, Kostantinos Oikonomakis, Panagiotis Giannakouras, Athanasios Vergados, Dimitrios Papaconstantinou
BACKGROUND: To report the negative effect of Nd: Yag (Neodymium-doped: Yttrium Aluminium Garnet) laser capsulotomy on the intraocular pressure (IOP) and the trabeculectomy bleb integrity, in a small series of eyes, both trabeculectomised and pseudophakic, following the laser application for the management of posterior capsular opacification (PCO). METHODS: This is a retrospective, non-comparative interventional case series study, in which 20 trabeculectomised and pseudophakic eyes from 15 patients, with otherwise well functioning blebs, were presented with uncontrolled IOP, in a variable distance of time following the application of YAG laser capsulotomy...
February 22, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28222711/pseudophakic-ametropia-management-with-toric-implantable-collamer-lens-with-a-central-hole-case-report
#15
Xun Chen, Xiaoying Wang, Xingtao Zhou
BACKGROUND: To report the clinical outcomes of correcting pseudophakic ametropia using toric implantable collamer lens with a 360 um central hole (TICL V4c). CASE PRESENTATION: The right eye of a 22-year-old male patient developed high myopia after unilateral phacoemulsification and intraocular lens (IOL) implantation following traumatic cataract 16 years ago. The manifest refraction was -11.50 DS/-2.50 DC × 175 with an uncorrected distance visual acuity (UDVA) of 20/2000 and a corrected distance visual acuity (CDVA) of 20/20...
February 21, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28219426/pseudophakic-cystoid-macular-edema-prevention-and-risk-factors-prospective-study-with-adjunctive-once-daily-topical-nepafenac-0-3-versus-placebo
#16
RANDOMIZED CONTROLLED TRIAL
Sean McCafferty, April Harris, Corin Kew, Tala Kassm, Lisa Lane, Jason Levine, Meisha Raven
BACKGROUND: Define the effectiveness of a topical non-steroidal anti-inflammatory drug (NSAID) added to topical steroid use after uncomplicated phacoemulsification for the prevention of pseudophakic cystoid macular edema (PCME) using a prospective, randomized, double-masked, placebo-controlled clinical study. METHODS: Eyes (1000) were randomized to placebo (497) or nepafenac 0.3% (503) used once daily, post-operatively for 5 weeks at two ophthalmology clinics. Diagnosis of PCME was made by clinical, ocular coherence tomography (OCT), and with fluorescein angiography confirmation...
February 20, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28219366/bacteriology-of-the-conjunctiva-in-pre-cataract-surgery-patients-with-occluded-nasolacrimal-ducts-and-the-operation-outcomes-in-japanese-patients
#17
Yuko Hayashi, Takeshi Miyamoto, Shuko Fujita, Katsuo Tomoyose, Nobuyuki Ishikawa, Masahide Kokado, Takayoshi Sumioka, Yuka Okada, Shizuya Saika
BACKGROUND: Contamination of the conjunctiva in association with nasolacrimal duct obstruction is by all accounts a risk factor for infectious endophthalmitis post-cataract surgery. METHODS: All patients who underwent cataract day surgery routinely received nasolacrimal duct syringing with normal saline at the Wakayama Medical University Hospital, Japan, from 2011 to 2013. The microorganisms isolated from conjunctival swab samples of patients with occluded nasolacrimal ducts and their susceptibility to antibiotics, as well as the operation outcomes in all the patients were retrospectively investigated...
February 20, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28219351/positive-bacterial-culture-in-conjunctival-sac-before-cataract-surgery-with-night-stay-is-related-to-diabetes-mellitus
#18
Tetsuhiro Kawata, Toshihiko Matsuo
BACKGROUND: The aim of this study is to elucidate background clinical factors in patients with positive bacterial culture for the conjunctival sac before cataract surgery in Japan. METHODS: Retrospective review was made on medical records of 576 consecutive patients who underwent conjunctival sac culture before cataract surgery with night stay at a hospital in 2 years from January 2013 to December 2014. In the patients with sequential bilateral surgeries, the data were chosen for bacterial culture in the eye which had earlier surgery...
February 20, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28202006/differences-in-serum-oxidative-status-between-glaucomatous-and-nonglaucomatous-cataract-patients
#19
Wojciech Rokicki, Jolanta Zalejska-Fiolka, Dorota Pojda-Wilczek, Alicja Hampel, Wojciech Majewski, Serap Ogultekin, Ewa Mrukwa-Kominek
BACKGROUND: Oxidative stress contributes to both intraocular pressure regulation and glaucomatous neuropathy. The systemic redox status (solitary determination) was examined in primary open-angle glaucoma (POAG) patients with cataract and nonglaucomatous cataract patients. Cataract-matched group comparisons appear more precise in the context of oxidative stress evaluation. The aim of this study was to establish if systemic oxidative status in POAG patients was elevated compared with the cataract only subjects...
February 15, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28196497/comparison-of-visual-outcomes-spectacles-dependence-and-patient-satisfaction-of-multifocal-and-accommodative-intraocular-lenses-innovative-perspectives-for-maximal-refractive-oriented-cataract-surgery
#20
COMPARATIVE STUDY
Raffaele Nuzzi, Federico Tridico
BACKGROUND: The aim of this study was to evaluate visual outcomes for different working distances (far, 60 cm and 33 cm) and impact on vision quality of multifocal IOLs AcrySof ResTOR SN6AD1 and SN6AD3 (Alcon, Inc., Fort Worth, Texas, USA) as well as REVIEW FIL611PV multifocal and OPTOFLEX FIL618 accommodative IOLs (Soleko, Ltd., Rome, Italy) in patients undergoing bilateral phacoemulsification. METHODS: In this observational prospective study 63 patients undergoing binocular cataract surgery were divided into four groups for implantation of one of the IOLs under evaluation...
February 14, 2017: BMC Ophthalmology
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