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BMC Ophthalmology

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https://www.readbyqxmd.com/read/29452583/does-rituximab-improve-clinical-outcomes-of-patients-with-thyroid-associated-ophthalmopathy-a-systematic-review-and-meta-analysis
#1
Changjun Wang, Qingyao Ning, Kai Jin, Jiajun Xie, Juan Ye
BACKGROUND: The current therapies of thyroid-associated ophthalmopathy (TAO) were still a challenging matter. In this study, we aimed to contrast the impact of before- after rituximab (RTX) therapy in the patients with TAO. METHODS: We searched the PubMed, EMBASE, and SCOPUS databases for articles published up to July 3, 2017. Fixed- or random-effects meta-analysis was used to provide pooled estimates of standard mean difference (SMD) both the primary outcome from clinical activity score (CAS), and secondary outcomes from thyrotropin receptor antibody (TRAb), proptosis, thyroid stimulating hormone (TSH), and interleukin-6 (IL-6) levels...
February 17, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29444665/comparison-of-1-year-outcomes-after-ahmed-glaucoma-valve-implantation-with-and-without-ologen-adjuvant
#2
Tai Jun Kim, Sohyun Kang, Jin Wook Jeoung, Young Kook Kim, Ki Ho Park
BACKGROUND: Many studies have investigated the clinical benefits of Ologen for trabeculectomy. However, its benefits for Ahmed glaucoma valve (AGV) implantation have not been investigated as extensively. The aim of this study was to compare the 1-year outcomes of AGV implantation with and without Ologen adjuvant for the treatment of refractory glaucoma. METHODS: This retrospective study included a total of 20 eyes of 20 glaucoma patients, who were followed for at least 1-year after undergoing AGV implantation...
February 14, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29444655/a-systematic-study-on-the-prevention-and-treatment-of-retinopathy-of-prematurity-in-china
#3
Shuman Xu, Zhijiang Liang, Qiyun Du, Zhankui Li, Guangming Tan, Chuan Nie, Yang Yang, Xuzai Lv, Chunyi Zhang, Xianqiong Luo
BACKGROUND: To identify the prevention situation, the main factors influencing prevention effects and to develop control measures over retinopathy of prematurity in China. METHODS: Using stratified random sampling method, we randomly selected 23 provincial and ministerial hospitals (8 in Guangdong province, 5 in Hunan province and 10 in Shaanxi province), 81 municipal hospitals (38 in Guangdong province, 19 in Hunan province and 24 in Shaanxi province), 180 district and county hospitals (76 in Guangdong province, 57 in Hunan province and 47 in Shaanxi province) in China...
February 14, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29439700/ocular-dimensions-of-the-chinese-adolescents-with-keratoconus
#4
Weijun Jian, Yang Shen, Yingjun Chen, Mi Tian, Xingtao Zhou
BACKGROUND: Adolescent KC is a special segment of the general KC population because an adolescents's eyes are still susceptible to blurred vision and optical defocus during the sensitive period of ocular and visual development. In the present study, we evaluated the ocular dimensions of 53 KC adolescents. METHODS: One hundred and six KC eyes of 53 (42 boys and 11 girls) KC adolescents (age 15.5 ± 1.7 years, range 11 to 18) were involved in this retrospective study...
February 13, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29439666/prevalence-and-causes-of-low-vision-and-blindness-in-an-elderly-population-in-nepal-the-bhaktapur-retina-study
#5
Raba Thapa, Sanyam Bajimaya, Govinda Paudyal, Shankar Khanal, Stevie Tan, Suman S Thapa, G H M B van Rens
BACKGROUND: This study aims to explore the prevalence and causes of low vision and blindness focused on retinal disease in a population above 60 years in Nepal. METHODS: Two thousand one hundred subjects were enrolled in a population-based cross-sectional study. History, presenting and best corrected visual acuity after subjective refraction, anterior and posterior segment examinations was obtained in detail. RESULTS: Among the total subjects, 1860 (88...
February 13, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29433477/prevalence-and-causes-of-blindness-visual-impairment-among-different-ethnical-minority-groups-in-xinjiang-uygur-autonomous-region-china
#6
Yanping Li, Wenyong Huang, Aoyun Qiqige, Hongwei Zhang, Ling Jin, Pula Ti, Jennifer Yip, Baixiang Xiao
BACKGROUND: The aim of this cross-sectional study is to ascertain the prevalence and causes of blindness, visual impairment, uptake of cataract surgery among different ethnic groups in Xinjiang Uygur Autonomous Region, China. METHODS: Four thousand one hundred fifty people at 50 years and above from different minority ethnic groups were randomly selected for an eye examination. The four trained eye teams collected data using tumbling E visual chart, torch, portable slit lamp and direct ophthalmoscope in 2015...
February 13, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29433472/factors-associated-with-developing-a-fear-of-falling-in-subjects-with-primary-open-angle-glaucoma
#7
Sayaka Adachi, Kenya Yuki, Sachiko Awano-Tanabe, Takeshi Ono, Daisuke Shiba, Hiroshi Murata, Ryo Asaoka, Kazuo Tsubota
BACKGROUND: To investigate the relationship between clinical risk factors, including visual field (VF) defects and visual acuity, and a fear of falling, among patients with primary open-angle glaucoma (POAG). METHODS: All participants answered the following question at a baseline ophthalmic examination: Are you afraid of falling? The same question was then answered every 12 months for 3 years. A binocular integrated visual field was calculated by merging a patient's monocular Humphrey field analyzer VFs, using the 'best sensitivity' method...
February 13, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29433463/scedosporium-apiospermum-infectious-scleritis-following-posterior-subtenon-triamcinolone-acetonide-injection-a-case-report-and-literature-review
#8
Daisuke Todokoro, Junki Hoshino, Ayaka Yo, Koichi Makimura, Junko Hirato, Hideo Akiyama
BACKGROUND: Ubiquitous fungi of the Scedosporium apiospermum species complex (SASC) cause various opportunistic infections. Posterior subtenon triamcinolone acetonide (STTA) injection is a standard therapy for intraocular inflammation and macular edema. We report a case of Scedosporium apiospermum infectious scleritis after a posterior STTA injection. CASE PRESENTATION: A 75-year-old man received a posterior STTA injection to treat macular edema in his left eye...
February 13, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29433476/trpv4-regulates-migration-and-tube-formation-of-human-retinal-capillary-endothelial-cells
#9
Lei Wen, Yue-Chun Wen, Gen-Jie Ke, Si-Qin Sun, Kai Dong, Lin Wang, Rong-Feng Liao
BACKGROUND: Ca2+ entry plays an important role in modulating endothelial cell migration and tube formation. Transient receptor potential cation channel subfamily V member 4 (TRPV4) is a Ca2+-permeable channel that is widely expressed in endothelial cells. It has been reported that TRPV4 is expressed in HRCECs and regulates Ca2+ entry. However, the function of TRPV4 in human retinal capillary endothelial cells (HRCECs) remains unknown. METHODS: In this study we used western blot and immunostaining assay to verify TRPV4 expression in HRCECs...
February 12, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29426303/a-rare-case-of-scleral-buckle-infection-with-curvularia-species
#10
Shalini Singh, Ankita Shrivastav, Manisha Agarwal, Arpan Gandhi, Rahul Mayor, Lagan Paul
BACKGROUND: Scleral buckling is an established modality of treating retinal detachment. Being an external implant the buckle may be prone to infections. We report such a case with a delayed presentation and a rare etiology. CASE PRESENTATION: A 45 year old male presented with redness, foreign body sensation and discharge for one month in his right eye. The patient had undergone a retinal detachment surgery elsewhere 14 years back without any visual gain. Right eye demonstrated no perception of light and the best corrected visual acuity in the left eye was 6/6, N6...
February 9, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29426296/repeated-intraocular-crystallization-of-ganciclovir-in-one-eye-after-bilateral-intravitreal-injections-a-case-report
#11
Lawrence P L Iu, Michelle C Y Fan, Wai-Ching Lam, Ian Y H Wong
BACKGROUND: Cytomegalovirus (CMV) retinitis is an opportunistic infection that primarily affects immunocompromised individuals. Intravitreal ganciclovir injection monotherapy or in combination with systemic anti-CMV therapy are effective treatments for CMV retinitis. Crystallization of ganciclovir after intravitreal injection is extremely rare. Only two cases had been reported in literature. Crystallization in only one eye after bilateral injections had not been reported before. We hereby report a case of intraocular ganciclovir crystallization in one eye after bilateral intravitreal injections, and repeated crystallization in the same eye after repeated injections...
February 9, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29426292/pre-treatment-clinical-features-in-central-retinal-vein-occlusion-that-predict-visual-outcome-following-intravitreal-ranibizumab
#12
Kerr Brogan, Monica Precup, Amanda Rodger, David Young, David Francis Gilmour
BACKGROUND: Predicting how patients with central retinal vein occlusion (CRVO) will respond to intravitreal anti-VEGF is challenging. The purpose of this study was to identify pre-treatment clinical features in CRVO that predict visual acuity (VA) following intravitreal ranibizumab. METHODS: Medical records, fundus images and optical coherence tomography (OCT) scans of treatment naïve patients with CRVO receiving PRN intravitreal ranibizumab were retrospectively reviewed...
February 9, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29422012/a-clinical-analysis-of-vitrectomy-for-severe-vitreoretinopathy-in-patients-with-chronic-renal
#13
Long Su, Guannan Huang, Songtao Yin, Xia Hua, Xin Tang
BACKGROUND: The recent advancement in the management of chronic renal failure (CRF) has significantly increased the longevity of the patients, which increase the incidence of severe vitreoretinopathy. The vitrectomy is highly risky in this particular group of patients due to their systemic comorbidity. The timing surgical intervention is usually delayed because of the systemic conditions. This study is to evaluate the safety and effectiveness of 25-guage vitrectomy for severe vitreoretinopathy in the CRF patients...
February 8, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29415670/the-alabama-vip-older-driver-study-rationale-and-design-examining-the-relationship-between-vision-impairment-and-driving-using-naturalistic-driving-techniques
#14
Cynthia Owsley, Gerald McGwin, Jonathan F Antin, Joanne M Wood, Jennifer Elgin
BACKGROUND: Older drivers aged ≥70 years old have among the highest rates of motor vehicle collisions (MVC) compared to other age groups. Driving is a highly visual task, and older adults have a high prevalence of vision impairment compared to other ages. Most studies addressing visual risk factors for MVCs by older drivers utilize vehicle accident reports as the primary outcome, an approach with several methodological limitations. Naturalistic driving research methods overcome these challenges and involve installing a high-tech, unobtrusive data acquisition system (DAS) in an older driver's own vehicle...
February 7, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29415667/short-term-effect-of-a-developed-warming-moist-chamber-goggle-for-video-display-terminal-associated-dry-eye
#15
Yueping Ren, Jie Chen, Qinxiang Zheng, Wei Chen
BACKGROUND: Video display terminal (VDT)-associated dry eye (DE) patients are the rising group worldwide, and moisture goggles are the preferable treatment since they are capable of improving tear film stability and DE discomfort. The current study aims to evaluate the short-term efficacy and safety of the developed warming moist chamber goggles (WMCGs) for VDT-associated DE patients. METHODS: In this prospective self-control study, 22 DE patients (22 eyes) working with VDTs over 4 h daily were enrolled and instructed to wear WMCGs for 15 min...
February 7, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29409486/antidepressants-use-and-risk-of-cataract-development-a-systematic-review-and-meta-analysis
#16
Yana Fu, Qi Dai, Liwei Zhu, Shuangqing Wu
BACKGROUND: Epidemiological studies suggest that antidepressants use may increase the risk of cataract, but the results are inconclusive. We aimed to examine this association by performing a systematic review and meta-analysis. METHODS: Relevant studies were identified by searching PubMed and Web of Science databases through June 2017. We included studies that reported risk estimates for the association between antidepressants use and cataract risk. A random-effects model was used to calculate the summary odds ratio (OR) with its 95% confidence interval (CI)...
February 6, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29409483/real-world-refractive-outcomes-of-toric-intraocular-lens-implantation-in-a-united-kingdom-national-health-service-setting
#17
Kanmin Xue, Jasleen K Jolly, Sonia P Mall, Shreya Haldar, Paul H Rosen, Robert E MacLaren
BACKGROUND: With increasing availability of toric intraocular lenses (IOL) for cataract surgery, real-world refractive outcome data is needed to aid the counselling of patients regarding lens choice. We aim to assess the outcomes of toric intraocular lens use in the non-specialist environment of a typical United Kingdom NHS cataract service. METHODS: A retrospective cohort study conducted at the Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, UK...
February 6, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29402259/correction-to-retinal-complications-of-gout-a-case-report-and-review-of-the-literature
#18
Ying Jiang, Jason E Brenner, William J Foster
After publication of the article [1], it has been brought to our attention that the images displayed in Figs. 1, 2 and 3 have been transposed.
February 5, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29402251/varicella-zoster-virus-associated-chorioretinitis-a-case-report
#19
Joo Yeon Kim, Ji Hwan Lee, Christopher Seungkyu Lee, Sung Chul Lee
BACKGROUND: Chorioretinitis is an unusual form of varicella zoster virus (VZV)-associated uveitis, and no report has described VZV-associated chorioretinitis using serial optical coherence tomography (OCT) images obtained during the course of resolution. CASE PRESENTATION: A 61-year-old woman presented with acute, unilateral vision loss in her right eye. Her visual acuity was count fingers in the right eye and 16/20 in the left eye, and she exhibited skin vesicles on her right forehead...
February 5, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29402238/effect-of-oral-colchicine-on-peripapillary-retinal-nerve-fiber-layer-thickness-in-patients-with-familial-mediterranean-fever
#20
Burak Tanyıldız, Mehmet Engin Tezcan, Baran Kandemir, Nesrin Tutaş Günaydın, Eren Göktaş, Aise Tangılntız, Aysu Karatay Arsan
BACKGROUND: The purpose of this study is to investigate whether oral colchicine has an effect on peripapillary retinal nerve fiber layer (pRNFL) thickness of familial Mediterranean fever (FMF) patients. METHODS: We conducted a cross sectional study by comparing pRNFL thickness of FMF patients on colchicine (treated group), newly diagnosed colchicine naïve FMF patients (untreated group) and healthy controls. The study included 66 FMF patients and 32 healthy control subjects...
February 5, 2018: BMC Ophthalmology
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