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Heart, Lung & Circulation

Gontse G Mokwatsi, Aletta E Schutte, Catharina M C Mels, Ruan Kruger
BACKGROUND: It is well established that an exaggerated morning blood pressure surge (MBPS) is associated with an increased risk for cardiovascular disease development in hypertensive individuals. However, in non-dipping individuals, a lower surge was reportedly associated with increased cardiovascular risk. Sympathetic nervous system activity is involved in 24-hour blood pressure fluctuations, including night-time dipping and the MBPS. To better understand this interaction, we investigated associations of MBPS with heart-rate variability and baroreceptor sensitivity in young healthy dippers and non-dippers...
July 30, 2018: Heart, Lung & Circulation
Gabriela Lima de Melo Ghisi, Sherry L Grace
BACKGROUND: One of the key drivers of cardiac rehabilitation under-utilisation is physician referral failure. The Physician Attitudes toward Cardiac Rehabilitation & Referral (PACRR) scale was developed to understand factors that impact their referral practices, so they can be ultimately reliably be identified and mitigated. The objectives of this study were to assess the reliability, factor structure, and validity of the PACRR. METHODS: Data were retrospectively analysed from three cohorts administering the PACRR, a 19-item scale...
July 21, 2018: Heart, Lung & Circulation
Con Aroney
No abstract text is available yet for this article.
July 19, 2018: Heart, Lung & Circulation
Harry G Mond
Modern cardiac pacing systems have sophisticated software to document, evaluate and record intrinsic and paced rhythms as well as correct pacing abnormalities and rhythm disturbances by applying algorithms, which are generally company specific. To the cardiologist and technologist, these algorithms may be difficult to interpret on both the 12-lead electrocardiograph (ECG) and Holter ambulatory monitoring recordings, which are usually performed because of patient symptoms or physician concern. The tracings may appear bewildering and mimic pacemaker malfunction, thus leading to unnecessary tests or even surgery...
July 18, 2018: Heart, Lung & Circulation
Laichun Song, Yaling Dong, Bo Wang, Jinjun Li, Xiaofei Qi, Xiang Gao, Zhengdong Hua, Chao Tao, Bihui He, Liang Tao
BACKGROUND: Minimally invasive cardiac surgery has become a safe and cosmetic alternative to standard median sternotomy. This retrospective study reviews our results and experience with the minimally invasive approach for congenital coronary artery fistula correction, compared with conventional approach. METHODS: From February 2001 to June 2016, 110 patients with isolated coronary artery fistula (CAF) in our centre underwent correction through minimally invasive approach (MIA) (n=65) or standard median sternotomy (SMS) (n=45)...
July 18, 2018: Heart, Lung & Circulation
Jae Gun Kwak, Sungkyu Cho, Woong-Han Kim
BACKGROUND: Open surgical implantation of epicardial leads in neonates and infants remains the first option of treatment. We reviewed the long-term outcomes after epicardial pacemaker implantation in neonates and infants. METHODS: From 1989 to 2016, 48 patients (16 neonates) underwent pacemaker implantation within the first year of life. Their median age and weight were 66.5days (range: 0∼319 days), and 4.2kg (range: 1.9∼9.3kg), respectively, at the time of first pacemaker implantation...
July 17, 2018: Heart, Lung & Circulation
Michael Z L Zhu, Molla M Huq, Baki M Billah, Lavinia Tran, Christopher M Reid, Kapilan Varatharajah, Franklin L Rosenfeldt
BACKGROUND: Coronary artery bypass grafting (CABG) performed early after acute myocardial infarction (AMI) carries a high risk of mortality. By avoiding cardioplegic arrest and aortic cross-clamping, on-pump beating heart CABG (ONBEAT) may benefit patients requiring urgent or emergency revascularisation in the setting of AMI. We evaluated the early and long-term outcomes of ONBEAT versus conventional CABG (ONSTOP) utilising the ANZSCTS National Cardiac Surgery Database. METHODS: Between 2001 and 2015, 5851 patients underwent non-elective on-pump CABG within 7 days of AMI...
July 12, 2018: Heart, Lung & Circulation
Rohan Poulter, David A Wood, Andrew Starovoytov, Stephanie Smith, Mehran Chitsaz, John Mayo
BACKGROUND: The aim of this study was to develop and describe percutaneous coronary angiographic techniques to create a porcine model of acute coronary stenosis with methacrylate plugs that can by assessed using fractional flow reserve (FFR), invasive coronary angiography and coronary computed tomographic (CT) perfusion imaging without introducing artefacts associated with surgical models. METHODS: Following animal care and institutional approval and using percutaneous coronary catheterisation techniques within an animal laboratory we introduced precision drilled methacrylate plugs into one of the three main coronary arteries of 10 experimental female pigs...
July 11, 2018: Heart, Lung & Circulation
Mark A Roll, Suzanne Kuys, James R Walsh, Oystein Tronstad, Marc D Ziegenfuss, Dan V Mullany
BACKGROUND: The study aims to determine long-term survival, health-related quality of life (HRQoL) and functional and physical outcomes of adult extra corporeal membrane oxygenation (ECMO) patients as there are limited and conflicting data in this area. METHODS: All patients receiving ECMO from April 2009 until June 2014 at The Prince Charles Hospital, Brisbane had Kaplan Meier survival calculated. Quality of life (QoL) was assessed using the Short Form Health Survey (SF-36v2), EQ5D-5L, The Frenchay Activities Index (FAI) and a return to work survey...
July 5, 2018: Heart, Lung & Circulation
Anatoly V Sikorsky, Menizibeya O Welcome, Vladimir A Pereverzev, Nikos E Mastorakis
BACKGROUND: There is a dearth and inconsistency of data on the role of the autonomic nervous system (ANS) in the development of arterial hypotension. Also, little is known about the involvement of endothelial factors in the development of this disease. The aim of the study was to investigate the role of the ANS and endothelial factors or vasoregulators in the development of primary arterial hypotension (PAH) in children. METHODS: The cardiointervalography and clino-orthostatic test results of 113 children with PAH were compared with 88 healthy children of comparable age (7-11 years)...
July 5, 2018: Heart, Lung & Circulation
Mehdi Eskandari, James Roy, Vasileios Tzalamouras, Rafal Dworakowski, Olaf Wendler, Mark Monaghan, Philip MacCarthy, Jonathan Byrne
Aortic paravalvular leakage (PVL) is a recognised complication of surgically replaced valves which is often treated using vascular plugs. Whilst transcatheter valve-in-valve therapy has been increasingly used for failed surgical bioprostheses, it is not considered as a treatment option for aortic PVL. However, the newer design of transcatheter aortic valves has a fabric skirt to create a more effective seal around the annulus. To our best knowledge, for the first time, we report successful adoption of the valve-in-valve therapy for the treatment of PVL in surgical bioprsthetic aortic valves such that the fabric skirt is placed immediately below the regurgitant orifice resulting in significant reduction in the PVL...
July 4, 2018: Heart, Lung & Circulation
Gerald Kaye, Jun Yen Ng, Shameer Ahmed, Diana Valencia, Danielle Harrop, Arnold C T Ng
BACKGROUND: Chronic right ventricular pacing may contribute to deterioration in left ventricular ejection fraction (LVEF). The aim of the study was to identify the prevalence of pacing-induced cardiomyopathy (PICM) in patients with chronic right ventricular pacing. METHODS: Patients attending a pacemaker clinic were retrospectively identified as having had transthoracic echocardiographic LVEF measurement during the 12 months prior to device implantation. Those with cardioverter-defibrillators or biventricular devices were excluded...
June 27, 2018: Heart, Lung & Circulation
Gerard M Healy, Angela McInerney, Aurelie Fabre, Gregory M Pastores, M Quinn, K McDonald, Jonathan D Dodd
No abstract text is available yet for this article.
June 23, 2018: Heart, Lung & Circulation
Rishi Sethi, Puneet Gupta, Akshyaya Pradhan, Mahim Saran, Bonnie R K Singh, Pravesh Vishwakarma, Monika Bhandari, Gaurav Chaudhary, Sharad Chandra, Akhil Sharma, S K Dwivedi, V S Narain
BACKGROUND: Owing to the growing evidence that the pathophysiology of obstructive sleep apnoea (OSA) and metabolic syndrome (MS) overlap considerably and both adversely impact cardiovascular health, we hypothesised that the presence of OSA with MS additively and adversely affect the severity of coronary artery disease (CAD). Exploration and understanding of this may have direct implications for the development of targeted, preventive strategies for CAD. Thus, this prospective study was aimed to determine the prevalence of 'Syndrome Z' in patients of MS who present with an acute coronary event and to correlate it with the angiographic severity of CAD in these patients...
June 23, 2018: Heart, Lung & Circulation
Benjamin K Ruth, Kenneth C Bilchick, Manu M Mysore, Hunter Mwansa, William C Harding, Younghoon Kwon, Jamie L W Kennedy, Jeremy A Mazurek, Andrew D Mihalek, LaVone A Smith, Eliany Mejia-Lopez, Alex M Parker, Timothy S Welch, Sula Mazimba
BACKGROUND: Pulmonary arterial hypertension (PAH) is characterised by remodelling of the pulmonary vasculature leading to right ventricular (RV) failure. The failing RV, through interventricular uncoupling, deleteriously impacts the left ventricle and overall cardiac efficiency. We hypothesised that the ratio of the pulmonary artery pulse pressure to the systemic pulse pressure ("pulmonary-systemic pulse pressure ratio", or PS-PPR) would be associated with mortality in PAH. METHODS: We conducted a retrospective analysis of 262 patients in the National Institute of Health Primary Pulmonary Hypertension Registry (NIH-PPH)...
June 21, 2018: Heart, Lung & Circulation
Monica Mu, Sandawana William Majoni, Pupalan Iyngkaran, Mark Haste, Nadarajah Kangaharan
BACKGROUND: Heart failure (HF) is associated with significant morbidity and mortality and recurrent hospitalisations, particularly in the Indigenous Australians of the Northern Territory. In remote Northern Australia, the epidemiology is less clear but anecdotal evidence suggests it may be worse. In addition, some anecdotal evidence suggests that prognostic pharmacological therapy could also be underutilised. Minimal HF data exists in the remote and Indigenous settings, making this study unique...
June 19, 2018: Heart, Lung & Circulation
Nikolaos A Papakonstantinou, Constantine N Antonopoulos, Nikolaos G Baikoussis, Ioannis Kakisis, Georgios Geroulakos
BACKGROUND: Conventional open total arch replacement is the treatment of choice for surgical aortic arch pathologies. However, it is a two-stage procedure related to high cumulative and interval mortality rates. Hybrid type III aortic arch reconstruction, the so-called "frozen elephant trunk" is a one-stage alternative approach. METHODS: A meta-analysis and detailed review of the literature published from January 2013 until December 2016, concerning frozen elephant trunk hybrid approach was conducted and data for morbidity and mortality rates were extracted...
June 11, 2018: Heart, Lung & Circulation
Bernadette Aliprandi-Costa, Lucy Morgan, Lan-Chi Snell, Mario D Souza, Leonard Kritharides, John French, David Brieger, Isuru Ranasinghe
BACKGROUND: Increased access to reperfusion for ST elevation myocardial infarction (STEMI) has contributed to reduced mortality internationally. We describe temporal trends in pre-hospital care, in-hospital management and outcomes of the STEMI population in Australia. METHODS: Temporal trends with multiple regression analysis on the management and outcomes of STEMI patients enrolled across 46 Australian hospitals in the Australian cohort of the Global Registry of Acute Coronary Events (GRACE) and the Cooperative National Registry of Acute Coronary Care Guideline Adherence and Clinical Events (CONCORDANCE) between February 1999 and August 2016...
June 11, 2018: Heart, Lung & Circulation
Ken Lee Chin, Mark Tacey, Christopher M Reid, Andrew Tonkin, Ingrid Hopper, Angela Brennan, Nick Andrianopoulos, Stephen J Duffy, David Clark, Andrew E Ajani, Danny Liew
BACKGROUND: Limited data exist on whether outcomes of patients with heart failure (HF) undergoing percutaneous coronary intervention (PCI) have improved over time. The purpose of this study was to assess temporal trends in patient characteristics, treatment and outcomes of patients with HF undergoing PCI. METHODS: Using data from the Melbourne Interventional Group (MIG), we evaluated temporal trends of procedure volume, major adverse cardiac events (MACE; a composite of all-cause mortality, myocardial infarction and target vessel revascularisation) and rates of cardiovascular readmission, all-cause death and cardiovascular death in consecutive patients with HF undergoing PCI...
June 8, 2018: Heart, Lung & Circulation
André La Gerche, Aaron Baggish, Hein Heidbuchel, Benjamin D Levine, Dhrubo Rakhit
The field of sports cardiology has advanced significantly over recent times. It has incorporated clinical and research advances in cardiac imaging, electrophysiology and exercise physiology to enable better diagnostic and therapeutic management of our patients. One important endeavour has been to try and better differentiate athletic cardiac remodelling from inherited cardiomyopathies and other pathologies. Whilst our diagnostic tools have improved, there have also been errors resulting from assumptions that the pathological traits observed in the general population would be generalisable to athletic populations...
June 6, 2018: Heart, Lung & Circulation
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