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Nature Reviews. Neuroscience

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https://www.readbyqxmd.com/read/30013080/bringing-back-early-memories
#1
Katherine Whalley
No abstract text is available yet for this article.
July 16, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30013079/a-narcotic-narcoleptic-link
#2
Natasha Bray
No abstract text is available yet for this article.
July 16, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30002509/on-the-nature-and-use-of-models-in-network-neuroscience
#3
REVIEW
Danielle S Bassett, Perry Zurn, Joshua I Gold
Network theory provides an intuitively appealing framework for studying relationships among interconnected brain mechanisms and their relevance to behaviour. As the space of its applications grows, so does the diversity of meanings of the term network model. This diversity can cause confusion, complicate efforts to assess model validity and efficacy, and hamper interdisciplinary collaboration. In this Review, we examine the field of network neuroscience, focusing on organizing principles that can help overcome these challenges...
July 12, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29991695/converging-inputs
#4
Darran Yates
No abstract text is available yet for this article.
July 10, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29991694/treasure-hunt
#5
Sian Lewis
No abstract text is available yet for this article.
July 10, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29977068/modelling-microglial-function-with-induced-pluripotent-stem-cells-an-update
#6
REVIEW
Jennifer M Pocock, Thomas M Piers
It is becoming increasingly apparent that microglia, the immune cells of the CNS, and their peripheral counterparts, macrophages, have a major role in normal physiology and pathology. Recent technological advances in the production of particular cell types from induced pluripotent stem cells have led to an interest in applying this methodology to the production of microglia. Here, we discuss recent advances in this area and describe how they will aid our future understanding of microglia.
July 5, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29970909/the-role-of-engram-cells-in-the-systems-consolidation-of-memory
#7
REVIEW
Susumu Tonegawa, Mark D Morrissey, Takashi Kitamura
What happens to memories as days, weeks and years go by has long been a fundamental question in neuroscience and psychology. For decades, researchers have attempted to identify the brain regions in which memory is formed and to follow its changes across time. The theory of systems consolidation of memory (SCM) suggests that changes in circuitry and brain networks are required for the maintenance of a memory with time. Various mechanisms by which such changes may take place have been hypothesized. Recently, several studies have provided insight into the brain networks driving SCM through the characterization of memory engram cells, their biochemical and physiological changes and the circuits in which they operate...
July 3, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29946158/sleep-it-off
#8
Natasha Bray
No abstract text is available yet for this article.
June 26, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29946157/neuroscience-of-apathy-and-anhedonia-a-transdiagnostic-approach
#9
REVIEW
Masud Husain, Jonathan P Roiser
Apathy and anhedonia are common syndromes of motivation that are associated with a wide range of brain disorders and have no established therapies. Research using animal models suggests that a useful framework for understanding motivated behaviour lies in effort-based decision making for reward. The neurobiological mechanisms underpinning such decisions have now begun to be determined in individuals with apathy or anhedonia, providing an important foundation for developing new treatments. The findings suggest that there might be some shared mechanisms between both syndromes...
June 26, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29934562/losing-sleep-over-lipids
#10
Natasha Bray
No abstract text is available yet for this article.
June 22, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29934561/opioid-receptors-drivers-to-addiction
#11
REVIEW
Emmanuel Darcq, Brigitte Lina Kieffer
Drug addiction is a worldwide societal problem and public health burden, and results from recreational drug use that develops into a complex brain disorder. The opioid system, one of the first discovered neuropeptide systems in the history of neuroscience, is central to addiction. Recently, opioid receptors have been propelled back on stage by the rising opioid epidemics, revolutions in G protein-coupled receptor research and fascinating developments in basic neuroscience. This Review discusses rapidly advancing research into the role of opioid receptors in addiction, and addresses the key questions of whether we can kill pain without addiction using mu-opioid-receptor-targeting opiates, how mu- and kappa-opioid receptors operate within the neurocircuitry of addiction and whether we can bridge human and animal opioid research in the field of drug abuse...
June 22, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29934560/trading-places
#12
Sian Lewis
No abstract text is available yet for this article.
June 22, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29934559/generation-of-circadian-rhythms-in-the-suprachiasmatic-nucleus
#13
REVIEW
Michael H Hastings, Elizabeth S Maywood, Marco Brancaccio
The suprachiasmatic nucleus (SCN) of the hypothalamus is remarkable. Despite numbering only about 10,000 neurons on each side of the third ventricle, the SCN is our principal circadian clock, directing the daily cycles of behaviour and physiology that set the tempo of our lives. When this nucleus is isolated in organotypic culture, its autonomous timing mechanism can persist indefinitely, with precision and robustness. The discovery of the cell-autonomous transcriptional and post-translational feedback loops that drive circadian activity in the SCN provided a powerful exemplar of the genetic specification of complex mammalian behaviours...
June 22, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29930349/influencing-identity
#14
Katherine Whalley
No abstract text is available yet for this article.
June 21, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29930348/a-matter-of-taste
#15
Katherine Whalley
No abstract text is available yet for this article.
June 21, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29930347/expanding-knowledge
#16
Katherine Whalley
No abstract text is available yet for this article.
June 21, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29880846/modulating-microglia
#17
Darran Yates
No abstract text is available yet for this article.
June 7, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29872219/a-pathway-less-travelled
#18
Sian Lewis
No abstract text is available yet for this article.
June 5, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29765160/author-correction-effects-of-adolescent-alcohol-consumption-on-the-brain-and-behaviour
#19
Linda P Spear
In the initially published version of this article, the following sentence was incorrect: "Studies that have compared equivalent exposures to alcohol in adolescent and adult animals have found that the effects of alcohol exposure during adolescence are generally not evident or are less pronounced than after comparable alcohol exposure in adulthood". The sentence should have read: "Studies that have compared equivalent exposures to alcohol in adolescent and adult animals have found that the effects of alcohol exposure during adulthood are generally not evident or are less pronounced than after comparable alcohol exposure in adolescence"...
May 15, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29765159/transition-to-chronic-pain-opportunities-for-novel-therapeutics
#20
Theodore J Price, Allan I Basbaum, Jacqueline Bresnahan, Jan F Chambers, Yves De Koninck, Robert R Edwards, Ru-Rong Ji, Joel Katz, Annemieke Kavelaars, Jon D Levine, Linda Porter, Neil Schechter, Kathleen A Sluka, Gregory W Terman, Tor D Wager, Tony L Yaksh, Robert H Dworkin
No abstract text is available yet for this article.
May 15, 2018: Nature Reviews. Neuroscience
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