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Nature Reviews. Neuroscience

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https://www.readbyqxmd.com/read/30305712/imaging-based-parcellations-of-the-human-brain
#1
REVIEW
Simon B Eickhoff, B T Thomas Yeo, Sarah Genon
A defining aspect of brain organization is its spatial heterogeneity, which gives rise to multiple topographies at different scales. Brain parcellation - defining distinct partitions in the brain, be they areas or networks that comprise multiple discontinuous but closely interacting regions - is thus fundamental for understanding brain organization and function. The past decade has seen an explosion of in vivo MRI-based approaches to identify and parcellate the brain on the basis of a wealth of different features, ranging from local properties of brain tissue to long-range connectivity patterns, in addition to structural and functional markers...
October 9, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30301952/a-position-on-vision
#2
Darran Yates
No abstract text is available yet for this article.
October 9, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30291302/number-crunching
#3
Katherine Whalley
No abstract text is available yet for this article.
October 5, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30291301/in-or-out-of-synch
#4
Natasha Bray
No abstract text is available yet for this article.
October 5, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30291300/rewarding-gut-feeling
#5
Sian Lewis
No abstract text is available yet for this article.
October 5, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30275464/it-s-about-time
#6
Katherine Whalley
No abstract text is available yet for this article.
October 1, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30266970/imaging-the-evolution-and-pathophysiology-of-alzheimer-disease
#7
REVIEW
William Jagust
Technologies for imaging the pathophysiology of Alzheimer disease (AD) now permit studies of the relationships between the two major proteins deposited in this disease - amyloid-β (Aβ) and tau - and their effects on measures of neurodegeneration and cognition in humans. Deposition of Aβ in the medial parietal cortex appears to be the first stage in the development of AD, although tau aggregates in the medial temporal lobe (MTL) precede Aβ deposition in cognitively healthy older people. Whether aggregation of tau in the MTL is the first stage in AD or a fairly benign phenomenon that may be transformed and spread in the presence of Aβ is a major unresolved question...
September 28, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30258219/incidental-associations
#8
Sian Lewis
No abstract text is available yet for this article.
September 26, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30410025/nonsense-mediated-rna-decay-in-the-brain-emerging-modulator-of-neural-development-and-disease
#9
REVIEW
Samie R Jaffrey, Miles F Wilkinson
Steady-state RNA levels are controlled by the balance between RNA synthesis and RNA turnover. A selective RNA turnover mechanism that has received recent attention in neurons is nonsense-mediated RNA decay (NMD). NMD has been shown to influence neural development, neural stem cell differentiation decisions, axon guidance and synaptic plasticity. In humans, NMD factor gene mutations cause some forms of intellectual disability and are associated with neurodevelopmental disorders, including schizophrenia and autism spectrum disorder...
November 8, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30405176/stop-don-t-prune-me
#10
Darran Yates
No abstract text is available yet for this article.
November 7, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30405175/author-correction-maintenance-reserve-and-compensation-the-cognitive-neuroscience-of-healthy-ageing
#11
Roberto Cabeza, Marilyn Albert, Sylvie Belleville, Fergus I M Craik, Audrey Duarte, Cheryl L Grady, Ulman Lindenberger, Lars Nyberg, Denise C Park, Patricia A Reuter-Lorenz, Michael D Rugg, Jason Steffener, M Natasha Rajah
In the originally published version of article, there were two errors in the references. The reference "Nilsson, J. & Lövdén, M. Naming is not explaining: future directions for the "cognitive reserve" and "brain maintenance" theories. Alzheimer's Res. Ther. 10, 34 (2018)" was missing. This reference has been added as REF. 14 in the HTML and PDF versions of the article and cited at the end of the sentence "However, over the years, these terms have been used inconsistently, creating confusion and slowing progress...
December 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30401802/versatile-control-of-synaptic-circuits-by-astrocytes-where-when-and-how
#12
REVIEW
Glenn Dallérac, Jonathan Zapata, Nathalie Rouach
Close structural and functional interactions of astrocytes with synapses play an important role in brain function. The repertoire of ways in which astrocytes can regulate synaptic transmission is complex so that they can both promote and dampen synaptic efficacy. Such contrasting effects raise questions regarding the determinants of these divergent astroglial functions. Recent findings provide insights into where, when and how astroglial regulation of synapses takes place by revealing major molecular and functional intrinsic heterogeneity as well as switches in astrocytes occurring during development or specific patterns of neuronal activity...
December 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30397322/towards-a-neuroscience-of-active-sampling-and-curiosity
#13
REVIEW
Jacqueline Gottlieb, Pierre-Yves Oudeyer
In natural behaviour, animals actively interrogate their environments using endogenously generated 'question-and-answer' strategies. However, in laboratory settings participants typically engage with externally imposed stimuli and tasks, and the mechanisms of active sampling remain poorly understood. We review a nascent neuroscientific literature that examines active-sampling policies and their relation to attention and curiosity. We distinguish between information sampling, in which organisms reduce uncertainty relevant to a familiar task, and information search, in which they investigate in an open-ended fashion to discover new tasks...
December 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30374151/keep-breathing
#14
Katherine Whalley
No abstract text is available yet for this article.
October 29, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30361501/fission-for-ltp
#15
Natasha Bray
No abstract text is available yet for this article.
October 25, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30356103/the-hippocampal-sharp-wave-ripple-in-memory-retrieval-for-immediate-use-and-consolidation
#16
REVIEW
Hannah R Joo, Loren M Frank
Various cognitive functions have long been known to require the hippocampus. Recently, progress has been made in identifying the hippocampal neural activity patterns that implement these functions. One such pattern is the sharp wave-ripple (SWR), an event associated with highly synchronous neural firing in the hippocampus and modulation of neural activity in distributed brain regions. Hippocampal spiking during SWRs can represent past or potential future experience, and SWR-related interventions can alter subsequent memory performance...
October 24, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30353063/hexagonal-pathfinding
#17
Sian Lewis
No abstract text is available yet for this article.
October 23, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30348965/boosting-regeneration
#18
Sian Lewis
No abstract text is available yet for this article.
October 22, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30348964/ca2-bursting
#19
Sian Lewis
No abstract text is available yet for this article.
October 22, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/30291299/author-correction-the-emerging-field-of-epigenetics-in-neurodegeneration-and-neuroprotection
#20
Jee-Yeon Hwang, Kelly A Aromolaran, R Suzanne Zukin
In Box 1 of this article, the positioning of the amino acid residues on the tail of histone H3 in part b of the figure was incorrect. These should have been oriented so that the K4 residue was the most distal labelled residue from the nucleosome core region. The corrected figure is shown below. The authors and editors thank T. Brown, R. Lober and C. Waker for bringing this error to our attention.
October 5, 2018: Nature Reviews. Neuroscience
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