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Nature Reviews. Neuroscience

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https://www.readbyqxmd.com/read/28179645/sleep-and-memory-rem-sleep-targets-new-synapses
#1
Katherine Whalley
No abstract text is available yet for this article.
February 9, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28179642/cell-biology-of-the-neuron-adding-fuel-to-the-firing
#2
Natasha Bray
No abstract text is available yet for this article.
February 9, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28179638/synaptic-transmission-recycling-regulators
#3
Katherine Whalley
No abstract text is available yet for this article.
February 9, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28148956/micro-connectomics-probing-the-organization-of-neuronal-networks-at-the-cellular-scale
#4
REVIEW
Manuel Schröter, Ole Paulsen, Edward T Bullmore
Defining the organizational principles of neuronal networks at the cellular scale, or micro-connectomics, is a key challenge of modern neuroscience. In this Review, we focus on graph theoretical parameters of micro-connectome topology, often informed by economical principles that conceptually originated with Ramón y Cajal's conservation laws. First, we summarize results from studies in intact small organisms and in samples from larger nervous systems. We then evaluate the evidence for an economical trade-off between biological cost and functional value in the organization of neuronal networks...
February 2, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28148955/glia-a-toxic-reaction
#5
Darran Yates
No abstract text is available yet for this article.
February 2, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28127034/sensory-systems-sensational-organization-in-the-dorsal-horn
#6
Katherine Whalley
No abstract text is available yet for this article.
January 27, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28053328/neural-development-relaying-control-of-neuronal-identity
#7
Katherine Whalley
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28275247/learning-and-memory-remembering-where-not-to-go
#8
Natasha Bray
No abstract text is available yet for this article.
April 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28251995/sleep-gaining-sleep-while-losing-synapses
#9
Sian Lewis
No abstract text is available yet for this article.
April 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28251994/sensory-processing-the-eyes-have-it
#10
Sian Lewis
No abstract text is available yet for this article.
April 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28251993/sense-of-agency-in-the-human-brain
#11
REVIEW
Patrick Haggard
In adult life, people normally know what they are doing. This experience of controlling one's own actions and, through them, the course of events in the outside world is called 'sense of agency'. It forms a central feature of human experience; however, the brain mechanisms that produce the sense of agency have only recently begun to be investigated systematically. This recent progress has been driven by the development of better measures of the experience of agency, improved design of cognitive and behavioural experiments, and a growing understanding of the brain circuits that generate this distinctive but elusive experience...
April 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28251992/neural-development-digit-development
#12
Sian Lewis
No abstract text is available yet for this article.
April 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28251991/synaptic-plasticity-kainate-receptors-can-ltp
#13
Sian Lewis
No abstract text is available yet for this article.
April 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28251990/operation-and-plasticity-of-hippocampal-ca3-circuits-implications-for-memory-encoding
#14
REVIEW
Nelson Rebola, Mario Carta, Christophe Mulle
The CA3 region of the hippocampus is important for rapid encoding of memory. Computational theories have proposed specific roles in hippocampal function and memory for the sparse inputs from the dentate gyrus to CA3 and for the extended local recurrent connectivity that gives rise to the CA3 autoassociative network. Recently, we have gained considerable new insight into the operation and plasticity of CA3 circuits, including the identification of novel forms of synaptic plasticity and their underlying mechanisms, and structural plasticity in the GABAergic control of CA3 circuits...
April 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28228638/pain-a-gatekeeper-circuit
#15
Katherine Whalley
No abstract text is available yet for this article.
April 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28228637/cell-biology-of-the-neuron-lightening-the-load
#16
Natasha Bray
No abstract text is available yet for this article.
April 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28303019/integration-of-optogenetics-with-complementary-methodologies-in-systems-neuroscience
#17
REVIEW
Christina K Kim, Avishek Adhikari, Karl Deisseroth
Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring local or global activity in timing, magnitude or individual-cell patterning. This outcome has been facilitated not only by the development of core features of optogenetics over the past 10 years (microbial-opsin variants, opsin-targeting strategies and light-targeting devices) but also by the recent integration of optogenetics with complementary technologies, spanning electrophysiology, activity imaging and anatomical methods for structural and molecular analysis...
March 17, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28303018/neurodegenerative-disease-a-chimeric-approach
#18
Darran Yates
No abstract text is available yet for this article.
March 17, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28303017/nmda-receptors-linking-physiological-output-to-biophysical-operation
#19
REVIEW
Gary J Iacobucci, Gabriela K Popescu
NMDA receptors are preeminent neurotransmitter-gated channels in the CNS, which respond to glutamate in a manner that integrates multiple external and internal cues. They belong to the ionotropic glutamate receptor family and fulfil unique and crucial roles in neuronal development and function. These roles depend on characteristic response kinetics, which reflect the operation of the receptors. Here, we review biologically salient features of the NMDA receptor signal and its mechanistic origins. Knowledge of distinctive NMDA receptor biophysical properties, their structural determinants and physiological roles is necessary to understand the physiological and neurotoxic actions of glutamate and to design effective therapeutics...
March 17, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28303016/the-two-century-journey-of-parkinson-disease-research
#20
REVIEW
Serge Przedborski
Since the first formal description of Parkinson disease (PD) two centuries ago, our understanding of this common neurodegenerative disorder has expanded at all levels of description, from the delineation of its clinical phenotype to the identification of its neuropathological features, neurochemical processes and genetic factors. Along the way, findings have led to novel hypotheses about how the disease develops and progresses, challenging our understanding of how neurodegenerative disorders wreak havoc on human health...
March 17, 2017: Nature Reviews. Neuroscience
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