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Nature Reviews. Neuroscience

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https://www.readbyqxmd.com/read/29773866/synaptic-building-blocks
#1
Katherine Whalley
No abstract text is available yet for this article.
May 17, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29765160/author-correction-effects-of-adolescent-alcohol-consumption-on-the-brain-and-behaviour
#2
Linda P Spear
In the initially published version of this article, the following sentence was incorrect: "Studies that have compared equivalent exposures to alcohol in adolescent and adult animals have found that the effects of alcohol exposure during adolescence are generally not evident or are less pronounced than after comparable alcohol exposure in adulthood". The sentence should have read: "Studies that have compared equivalent exposures to alcohol in adolescent and adult animals have found that the effects of alcohol exposure during adulthood are generally not evident or are less pronounced than after comparable alcohol exposure in adolescence"...
May 15, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29765159/transition-to-chronic-pain-opportunities-for-novel-therapeutics
#3
Theodore J Price, Allan I Basbaum, Jacqueline Bresnahan, Jan F Chambers, Yves De Koninck, Robert R Edwards, Ru-Rong Ji, Joel Katz, Annemieke Kavelaars, Jon D Levine, Linda Porter, Neil Schechter, Kathleen A Sluka, Gregory W Terman, Tor D Wager, Tony L Yaksh, Robert H Dworkin
No abstract text is available yet for this article.
May 15, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29752468/foraging-for-foundations-in-decision-neuroscience-insights-from-ethology
#4
REVIEW
Dean Mobbs, Pete C Trimmer, Daniel T Blumstein, Peter Dayan
Modern decision neuroscience offers a powerful and broad account of human behaviour using computational techniques that link psychological and neuroscientific approaches to the ways that individuals can generate near-optimal choices in complex controlled environments. However, until recently, relatively little attention has been paid to the extent to which the structure of experimental environments relates to natural scenarios, and the survival problems that individuals have evolved to solve. This situation not only risks leaving decision-theoretic accounts ungrounded but also makes various aspects of the solutions, such as hard-wired or Pavlovian policies, difficult to interpret in the natural world...
May 11, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29743685/a-regional-divide
#5
Katherine Whalley
No abstract text is available yet for this article.
May 9, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29743684/creating-a-diversion
#6
Sian Lewis
No abstract text is available yet for this article.
May 9, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29740175/breathing-matters
#7
REVIEW
Christopher A Del Negro, Gregory D Funk, Jack L Feldman
Breathing is a well-described, vital and surprisingly complex behaviour, with behavioural and physiological outputs that are easy to directly measure. Key neural elements for generating breathing pattern are distinct, compact and form a network amenable to detailed interrogation, promising the imminent discovery of molecular, cellular, synaptic and network mechanisms that give rise to the behaviour. Coupled oscillatory microcircuits make up the rhythmic core of the breathing network. Primary among these is the preBötzinger Complex (preBötC), which is composed of excitatory rhythmogenic interneurons and excitatory and inhibitory pattern-forming interneurons that together produce the essential periodic drive for inspiration...
May 8, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29740174/rett-syndrome-insights-into-genetic-molecular-and-circuit-mechanisms
#8
REVIEW
Jacque P K Ip, Nikolaos Mellios, Mriganka Sur
Rett syndrome (RTT) is a severe neurological disorder caused by mutations in the gene encoding methyl-CpG-binding protein 2 (MeCP2). Almost two decades of research into RTT have greatly advanced our understanding of the function and regulation of the multifunctional protein MeCP2. Here, we review recent advances in understanding how loss of MeCP2 impacts different stages of brain development, discuss recent findings demonstrating the molecular role of MeCP2 as a transcriptional repressor, assess primary and secondary effects of MeCP2 loss and examine how loss of MeCP2 can result in an imbalance of neuronal excitation and inhibition at the circuit level along with dysregulation of activity-dependent mechanisms...
May 8, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29740173/an-expanding-role
#9
Darran Yates
No abstract text is available yet for this article.
May 8, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29740172/the-power-of-3-utrs
#10
Natasha Bray
No abstract text is available yet for this article.
May 8, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29717205/pathways-to-contextual-control
#11
Katherine Whalley
No abstract text is available yet for this article.
May 1, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29717204/synaptic-nibbling
#12
Grant Otto
No abstract text is available yet for this article.
May 1, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29686310/continued-access-to-investigational-brain-implants
#13
Gabriel Lázaro-Muñoz, Daniel Yoshor, Michael S Beauchamp, Wayne K Goodman, Amy L McGuire
No abstract text is available yet for this article.
April 24, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29670185/time-to-get-tough
#14
Natasha Bray
No abstract text is available yet for this article.
April 18, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29666508/intrinsic-mechanisms-of-neuronal-axon-regeneration
#15
REVIEW
Marcus Mahar, Valeria Cavalli
Permanent disabilities following CNS injuries result from the failure of injured axons to regenerate and rebuild functional connections with their original targets. By contrast, injury to peripheral nerves is followed by robust regeneration, which can lead to recovery of sensory and motor functions. This regenerative response requires the induction of widespread transcriptional and epigenetic changes in injured neurons. Considerable progress has been made in recent years in understanding how peripheral axon injury elicits these widespread changes through the coordinated actions of transcription factors, epigenetic modifiers and, to a lesser extent, microRNAs...
April 17, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29643480/the-basal-ganglia-and-the-cerebellum-nodes-in-an-integrated-network
#16
REVIEW
Andreea C Bostan, Peter L Strick
The basal ganglia and the cerebellum are considered to be distinct subcortical systems that perform unique functional operations. The outputs of the basal ganglia and the cerebellum influence many of the same cortical areas but do so by projecting to distinct thalamic nuclei. As a consequence, the two subcortical systems were thought to be independent and to communicate only at the level of the cerebral cortex. Here, we review recent data showing that the basal ganglia and the cerebellum are interconnected at the subcortical level...
April 11, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29618808/fibrinogen-in-neurological-diseases-mechanisms-imaging-and-therapeutics
#17
REVIEW
Mark A Petersen, Jae Kyu Ryu, Katerina Akassoglou
The blood coagulation protein fibrinogen is deposited in the brain in a wide range of neurological diseases and traumatic injuries with blood-brain barrier (BBB) disruption. Recent research has uncovered pleiotropic roles for fibrinogen in the activation of CNS inflammation, induction of scar formation in the brain, promotion of cognitive decline and inhibition of repair. Such diverse roles are possible in part because of the unique structure of fibrinogen, which contains multiple binding sites for cellular receptors and proteins expressed in the nervous system...
April 5, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29618806/neural-circuits-balancing-threats
#18
Katherine Whalley
No abstract text is available yet for this article.
April 5, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29618805/techniques-in-a-split-sequence
#19
Sian Lewis
No abstract text is available yet for this article.
April 5, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29618804/techniques-meg-in-motion
#20
Sian Lewis
No abstract text is available yet for this article.
April 5, 2018: Nature Reviews. Neuroscience
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