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Nature Reviews. Genetics

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https://www.readbyqxmd.com/read/30209350/the-girl-with-neanderthal-and-denisovan-parents
#1
Dorothy Clyde
No abstract text is available yet for this article.
September 12, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30154482/full-speed-ahead-for-single-cell-analysis
#2
Darren J Burgess
No abstract text is available yet for this article.
August 28, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30135477/in-vivo-lineage-tracing-in-mice
#3
Linda Koch
No abstract text is available yet for this article.
August 22, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30111830/understanding-explosive-diversification-through-cichlid-fish-genomics
#4
REVIEW
Walter Salzburger
Owing to their taxonomic, phenotypic, ecological and behavioural diversity and propensity for explosive diversification, the assemblages of cichlid fish in the East African Great Lakes Victoria, Malawi and Tanganyika are important role models in evolutionary biology. With the release of five reference genomes and many additional genomic resources, as well as the establishment of functional genomic tools, the cichlid system has fully entered the genomic era. The in-depth genomic exploration of the East African cichlid fauna - in combination with the examination of their ecology, morphology and behaviour - permits novel insights into the way organisms diversify...
August 15, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30093724/lessons-from-1-million-genomes
#5
Michelle Trenkmann
No abstract text is available yet for this article.
August 9, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30093723/foxp2-tells-a-cautionary-tale
#6
Rebecca Furlong
No abstract text is available yet for this article.
August 9, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30089805/stem-cell-bioengineering-building-from-stem-cell-biology
#7
REVIEW
Mukul Tewary, Nika Shakiba, Peter W Zandstra
New fundamental discoveries in stem cell biology have yielded potentially transformative regenerative therapeutics. However, widespread implementation of stem-cell-derived therapeutics remains sporadic. Barriers that impede the development of these therapeutics can be linked to our incomplete understanding of how the regulatory networks that encode stem cell fate govern the development of the complex tissues and organs that are ultimately required for restorative function. Bioengineering tools, strategies and design principles represent core components of the stem cell bioengineering toolbox...
August 8, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30082855/transcriptomics-in-intact-tissues
#8
Linda Koch
No abstract text is available yet for this article.
August 6, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30082854/evolution-of-eusociality
#9
Linda Koch
No abstract text is available yet for this article.
August 6, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30069060/dynamic-rnas-in-sperm-shape-embryo-development
#10
Ross Cloney
No abstract text is available yet for this article.
August 1, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30054568/high-throughput-determination-of-rna-structures
#11
REVIEW
Eric J Strobel, Angela M Yu, Julius B Lucks
RNA performs and regulates a diverse range of cellular processes, with new functional roles being uncovered at a rapid pace. Interest is growing in how these functions are linked to RNA structures that form in the complex cellular environment. A growing suite of technologies that use advances in RNA structural probes, high-throughput sequencing and new computational approaches to interrogate RNA structure at unprecedented throughput are beginning to provide insights into RNA structures at new spatial, temporal and cellular scales...
July 27, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30054567/how-to-predict-the-future
#12
Anna Dart
No abstract text is available yet for this article.
July 27, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30018367/cytonuclear-integration-and-co-evolution
#13
REVIEW
Daniel B Sloan, Jessica M Warren, Alissa M Williams, Zhiqiang Wu, Salah E Abdel-Ghany, Adam J Chicco, Justin C Havird
The partitioning of genetic material between the nucleus and cytoplasmic (mitochondrial and plastid) genomes within eukaryotic cells necessitates coordinated integration between these genomic compartments, with important evolutionary and biomedical implications. Classic questions persist about the pervasive reduction of cytoplasmic genomes via a combination of gene loss, transfer and functional replacement - and yet why they are almost always retained in some minimal form. One striking consequence of cytonuclear integration is the existence of 'chimeric' enzyme complexes composed of subunits encoded in two different genomes...
July 17, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/29995837/diagnosis-and-management-of-cornelia-de-lange-syndrome-first-international-consensus-statement
#14
REVIEW
Antonie D Kline, Joanna F Moss, Angelo Selicorni, Anne-Marie Bisgaard, Matthew A Deardorff, Peter M Gillett, Stacey L Ishman, Lynne M Kerr, Alex V Levin, Paul A Mulder, Feliciano J Ramos, Jolanta Wierzba, Paola Francesca Ajmone, David Axtell, Natalie Blagowidow, Anna Cereda, Antonella Costantino, Valerie Cormier-Daire, David FitzPatrick, Marco Grados, Laura Groves, Whitney Guthrie, Sylvia Huisman, Frank J Kaiser, Gerritjan Koekkoek, Mary Levis, Milena Mariani, Joseph P McCleery, Leonie A Menke, Amy Metrena, Julia O'Connor, Chris Oliver, Juan Pie, Sigrid Piening, Carol J Potter, Ana L Quaglio, Egbert Redeker, David Richman, Claudia Rigamonti, Angell Shi, Zeynep T├╝mer, Ingrid D C Van Balkom, Raoul C Hennekam
Cornelia de Lange syndrome (CdLS) is an archetypical genetic syndrome that is characterized by intellectual disability, well-defined facial features, upper limb anomalies and atypical growth, among numerous other signs and symptoms. It is caused by variants in any one of seven genes, all of which have a structural or regulatory function in the cohesin complex. Although recent advances in next-generation sequencing have improved molecular diagnostics, marked heterogeneity exists in clinical and molecular diagnostic approaches and care practices worldwide...
July 11, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/29993033/the-genetics-of-loneliness
#15
Dorothy Clyde
No abstract text is available yet for this article.
July 11, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/29934629/prospecting-for-pluripotency
#16
Dorothy Clyde
No abstract text is available yet for this article.
June 22, 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30042480/koala-genome-insights
#17
Darren J Burgess
No abstract text is available yet for this article.
September 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30022106/gold-rush-to-gene-editing-in-the-brain
#18
Michelle Trenkmann
No abstract text is available yet for this article.
September 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/30013225/concentrating-on-intrinsic-disorder
#19
Paulina Strzyz
No abstract text is available yet for this article.
September 2018: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/29973680/population-genomics-of-bacterial-host-adaptation
#20
REVIEW
Samuel K Sheppard, David S Guttman, J Ross Fitzgerald
Some bacteria can transfer to new host species, and this poses a risk to human health. Indeed, an estimated 60% of all human pathogens have originated from other animal species. Similarly, human-to-animal transitions are recognized as a major threat to sustainable livestock production, and emerging pathogens impose an increasing burden on crop yield and global food security. Recent advances in high-throughput sequencing technologies have enabled comparative genomic analyses of bacterial populations from multiple hosts...
September 2018: Nature Reviews. Genetics
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