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Otology & Neurotology

Griet Mertens, Annick Gilles, Rajae Bouzegta, Paul Van de Heyning
BACKGROUND: Recently, an adhesive bone conduction hearing system has been developed for conductive hearing loss or single-sided deafness (SSD). In SSD cases, this device may be a good solution for patients who are unsuitable for, or who do not wish to undergo, bone conduction implant or cochlear implant surgery. The study aimed to investigate the hearing outcomes with the adhesive hearing system in SSD. PURPOSE OF THE STUDY: The study aimed to investigate the hearing outcomes with the adhesive hearing system in SSD...
July 16, 2018: Otology & Neurotology
Jie Yang, Huan Jia, Gen Li, Meiping Huang, Weidong Zhu, Zhaoyan Wang, Yun Li, Hao Wu
OBJECTIVE: To evaluate the objective and subjective effects of intratympanic gentamicin treatment in patients with small vestibular schwannomas who exhibit intractable vertigo. PATIENTS: Individuals diagnosed with small vestibular schwannomas who exhibited intractable vertigo were retrospectively reviewed. INTERVENTIONS: Intratympanic gentamicin injection. MAIN OUTCOME MEASURES: Vertigo control. RESULTS: Eight patients were included in the study...
July 16, 2018: Otology & Neurotology
Yun Jung Bae, Jae-Jin Song, Byung Se Choi, Young Kang, Jae Hyoung Kim, Ja-Won Koo
OBJECTIVE: Distinguishing intralabyrinthine schwannoma (ILS) from labyrinthitis is crucial in deciding patient management between surgery and medication; however, the clinical and radiological differentiation between ILS and labyrinthitis is difficult, especially when labyrinthitis shows contrast-enhancement mimicking ILS on magnetic resonance imaging (MRI). This study aimed to evaluate the quantitative characteristics of signal intensity on 3T MRI for differentiating ILS from contrast-enhancing labyrinthitis (CEL)...
July 16, 2018: Otology & Neurotology
Andrea Bacciu, Filippo Di Lella, Ilaria Iaccarino, Enrico Pasanisi, Giovanni Fava, Vincenzo Vincenti, Maurizio Falcioni
OBJECTIVE: Marshall syndrome is a genetic disorder caused by mutations in the COL11A1 gene. This syndrome is characterized by skeletal, ophthalmologic, craniofacial, and auditory abnormalities. Hearing loss is among the main manifestations reported in this disorder being observed in approximately 80% of affected individuals.The present study aims to describe the audiologic characteristics of three members of a family with Marshall syndrome and also serves as a review of the literature...
July 16, 2018: Otology & Neurotology
Eric J Formeister, Habib G Rizk, Michael A Kohn, Jeffrey D Sharon
OBJECTIVES: 1. Describe the epidemiology of vestibular migraine (VM) in the United States, using data from the 2008 National Health Interview Survey (NHIS). 2. Characterize the sociodemographic and clinical attributes of people with VM. STUDY DESIGN: Population-based nationwide survey study of US adults. PATIENTS: Adult respondents to the 2008 NHIS. MAIN OUTCOME MEASURES: The responses of participants in the 2008 NHIS balance and dizziness supplement (n = 21,781) were analyzed using statistical software...
July 16, 2018: Otology & Neurotology
Danielle R Trakimas, Elliott D Kozin, Iman Ghanad, Joseph B Nadol, Aaron K Remenschneider
HYPOTHESIS: We hypothesize that human cases of cochlear implantation (CI) with folding of the electrode array will demonstrate greater degrees of intracochlear ossification, lower spiral ganglion neuron (SGN) counts, and poorer audiometric outcomes. BACKGROUND: CI electrode array folding, such folding of the proximal array, is a relatively common surgical complication that can occur with forceful electrode insertion and may be an important and avoidable factor affecting implant outcomes...
July 13, 2018: Otology & Neurotology
Cynthia M Chweya, Neil S Patel, William F Young, Bruce E Pollock, Michael J Link, Matthew L Carlson
OBJECTIVES: Catecholamine-secreting jugular paragangliomas (JPs) represent a rare subset of head and neck paragangliomas that may present with hypertension, arrhythmia, or syncopal episodes. Subtotal resection to protect critical neurovascular structures may result in persistent catecholamine excess from residual tumor. Herein, we report our experience with stereotactic radiosurgery (SRS) for salvage treatment of catecholamine-secreting JP following subtotal microsurgical resection. PATIENTS: Adult patients treated with SRS after subtotal microsurgical resection of catecholamine-secreting JP...
July 13, 2018: Otology & Neurotology
So Young Kim, Gaon Jung, Ye Ji Shim, Ja-Won Koo
HYPOTHESIS: We tested whether GV1001 has any ototoxic side effects at different doses and whether it protects hearing in an aminoglycoside-induced ototoxicity mouse model. BACKGROUND: GV1001, a novel peptide vaccine currently being examined in a Phase 3 clinical trial to treat pancreatic cancer, also has anti-inflammatory and antioxidant effects. METHODS: In the first experiment, C57/BL6 mice were injected with GV1001 preparations at concentrations of 0...
July 13, 2018: Otology & Neurotology
Thi-Thao Tran, Te-Yung Fang, Van-Truong Pham, Chen Lin, Pa-Chun Wang, Men-Tzung Lo
HYPOTHESIS: The artificial intelligence and image processing technology can develop automatic diagnostic algorithm for pediatric otitis media (OM) with accuracy comparable to that from well-trained otologists. BACKGROUND: OM is a public health issue that occurs commonly in pediatric population. Caring for OM may incur significant indirect cost that stems mainly from loss of school or working days seeking for medical consultation. It makes great sense for the homecare of OM...
July 13, 2018: Otology & Neurotology
Arnaud Attyé, Michael Eliezer
No abstract text is available yet for this article.
July 13, 2018: Otology & Neurotology
Daniel Schurzig, Max Eike Timm, Cornelia Batsoulis, Samuel John, Thomas Lenarz
HYPOTHESIS: Methods for cochlear coverage determination vary in their accuracy and are hence not equally reliable. BACKGROUND: The audiological outcome after cochlear implantation is known to depend on several factors. One factor shown to positively correlate with speech perception is the insertion angle. This parameter is one of the ways to describe the fraction of the cochlea spiral exposed to electric stimulation after implantation, also known as cochlear coverage, which itself is dependent on the length and type of electrode array as well as the size and shape of the implanted cochlea...
July 13, 2018: Otology & Neurotology
Tom Gawliczek, Fabio Munzinger, Lukas Anschuetz, Marco Caversaccio, Martin Kompis, Wilhelm Wimmer
OBJECTIVE: To assess the audiological benefit of a noninvasive, adhesively attached bone conduction device (BCD1) in subjects with induced bilateral conductive hearing loss. Secondary objectives were to evaluate the additional benefit of bilateral fitting compared with unilateral fitting and to compare the outcomes with bone conduction devices attached to a softband (BCD2). STUDY DESIGN: Prospective nonrandomized crossover study. SETTING: Tertiary referral center...
July 13, 2018: Otology & Neurotology
Brent P Spehar, Jeffery T Lichtenhan
HYPOTHESIS: Persons with normal audiometric thresholds but excessive difficulty hearing in background noise will choose auditory training as a treatment option. BACKGROUND: Auditory training has traditionally been reserved for those with marked hearing loss. We investigated auditory training as a treatment option for those who have normal auditory thresholds but complain about hearing in noise-a population of patients for which no therapy or intervention currently exists...
July 9, 2018: Otology & Neurotology
John P Marinelli, Stephen P Cass, Scott E Mann, David S Haynes, Jacob B Hunter, Brandon Isaacson, Alex D Sweeney, Stanley Pelosi, Thomas O Willcox, Brendan P O'Connell, Michael Rivera, John I Lane, Matthew L Carlson
OBJECTIVE: To date, less than 150 cases of middle ear adenomatous neuroendocrine tumors (MEANTs) have been reported in the English literature. The objective of this study was to provide a contemporary analysis of these rare lesions and develop a consensus-driven staging system. STUDY DESIGN: Multi-institutional retrospective histopathologic, radiologic, and clinical review. SETTING: Six tertiary referral centers. PATIENTS: Thirty-two patients with pathologically confirmed MEANT...
July 9, 2018: Otology & Neurotology
Enrique R Perez, Olena Bracho, Liliana Ein, Mikhaylo Szczupak, Paula V Monje, Cristina Fernandez-Valle, Abdulaziz Alshaiji, Michael Ivan, Jacques Morcos, Xue-Zhong Liu, Michael Hoffer, Adrien Eshraghi, Simon Angeli, Fred Telischi, Christine T Dinh
HYPOTHESIS: Merlin-deficient Schwann cells (MD-SC) and primary human vestibular schwannoma (VS) cells exhibit selective uptake of sodium-fluorescein (SF), allowing for fluorescent detection and improved visualization of tumor cells, when compared with Schwann cells (SC). BACKGROUND: SF is a fluorescent compound used for fluorescence-guided resection of gliomas. The utility of SF for VS surgery has not been assessed. METHODS: Mouse MD-SCs and rat SCs were cultured on 96-well plates at different cell densities and treated with SF at several drug concentrations and durations...
July 9, 2018: Otology & Neurotology
Rahul K Sharma, Stephanie Y Chen, Jedidiah Grisel, Justin S Golub
OBJECTIVE: In the era of big data, it is critical to aggregate results across different institutions. This is a major challenge for cochlear implant (CI) research given multiple, incompatible outcome measures. We use a large, national CI database to develop a formula to convert between the two most common measures: Consonant-Nucleus-Consonant word (CNCw) and Arizona Biomedical (AzBio). We then use this tool to analyze hearing outcomes in older adults with a single, universal outcome measure...
July 9, 2018: Otology & Neurotology
So Young Kim, Jae-Sung Lim, Songyong Sim, Hyo Geun Choi
OBJECTIVES: To investigate the risk of stroke in SSNHL patients. STUDY DESIGN: A longitudinal follow-up cohort study. SETTING: The Korean National Health Insurance Service-National Sample Cohort from 2002 to 2013. PATIENTS: The 4,944 SSNHL participants were matched with 19,776 controls for age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia. The SSNHL subjects were diagnosed (International Classification of Disease [ICD]-10: H91...
July 9, 2018: Otology & Neurotology
Andrew E Bluher, Stephanie Moody-Antonio
No abstract text is available yet for this article.
July 9, 2018: Otology & Neurotology
Jordan B Hochman, Justyn Pisa, Bonnie Cham
INTRODUCTION: Cochlear reimplantation procedures account for approximately 5% of all implant cases and may be caused by internal device failure, skin flap complications, or an unexpected decline in auditory performance. This issue, in concert with changing demographics, expanded audiometric candidacy criteria, adult bilateral implantation, and implantation for unilateral hearing loss, all place escalating pressure on device availability and resource allocation in a publically funded health care system...
July 9, 2018: Otology & Neurotology
Marco Hoesli, Alexander Huber, Flurin Pfiffner, Dorothe Veraguth, Christof Roosli, Adrian Dalbert
OBJECTIVE: To assess changes in electrocochleographic (ECoG) responses following short-term suprathreshold electrical stimulation during cochlear implant (CI) telemetry in CI recipients. METHODS: Extracochlear ECoG recordings were conducted before and after intraoperative short-term suprathreshold electrical stimulation. Tone bursts at 500, 750, and 1000 Hz as well as clicks were used as acoustic stimuli. Changes of ECoG responses were correlated to calculated maximum electrical charge levels...
July 6, 2018: Otology & Neurotology
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