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Otology & Neurotology

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https://www.readbyqxmd.com/read/28538472/efficacy-of-intratympanic-gentamicin-in-m%C3%A3-ni%C3%A3-re-s-disease-with-and-without-migraine
#1
Yuan F Liu, Elizabeth Renk, Steven D Rauch, Helen X Xu
OBJECTIVE: To compare the efficacy of intratympanic gentamicin injection (ITG) on vertigo control, drop attacks, and functional level in Ménière's disease patients with and without a history of migraine. PATIENTS: Ménière's disease patients (patients with migraine and age- and sex-matched control patients without migraine) treated from 2002 to 2012 who failed medical management and received ITG, with a minimum 2-year follow up. INTERVENTION: ITG...
May 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28538471/foreign-body-response-to-silicone-in-cochlear-implant-electrodes-in-the-human
#2
Jennifer T O'Malley, Barbara J Burgess, Donald Galler, Joseph B Nadol
HYPOTHESIS: Silicone as part of a cochlear implant electrode may be responsible for a foreign body response in the human. BACKGROUND: Clinical evidence of a foreign body response to a cochlear implant has been reported. In a previous study, particulate material found within the fibrous sheath and within macrophages surrounding a cochlear implant has been identified as being consistent with platinum. However, to date, there has been no histologic evidence of a role for silicone in this cellular immune response...
May 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28538470/progression-of-unilateral-hearing-loss-in-children-with-and-without-ipsilateral-cochlear-nerve-canal-stenosis-a-hazard-analysis
#3
Patricia L Purcell, Justin R Shinn, Scott S Coggeshall, Grace Phillips, Angelisa Paladin, Kathleen C Y Sie, David L Horn
OBJECTIVE: To investigate the risk of hearing loss progression in each ear among children with unilateral hearing loss associated with ipsilateral bony cochlear nerve canal (BCNC) stenosis. SETTING: Tertiary pediatric referral center. PATIENTS: Children diagnosed with unilateral hearing loss who had undergone temporal bone computed tomography imaging and had at least 6 months of follow-up audiometric testing were identified from a prospective audiological database...
May 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28538469/an-assessment-of-the-clinical-acceptability-of-direct-acoustic-cochlear-implantation-for-adults-with-advanced-otosclerosis-in-the-united-kingdom
#4
Pádraig Thomas Kitterick, Guna Reddy-Kolanu, David Baguley, Jeremey Lavy, Peter Monksfield, Rupan Banga, Jaydip Ray, Ad Snik, Gerard M O'Donoghue
HYPOTHESIS: Assess the clinical acceptability of direct acoustic cochlear implantation for patients with advanced otosclerosis and the support for conducting a controlled trial of its effectiveness in the United Kingdom. BACKGROUND: Emerging evidence supports the efficacy of direct acoustic cochlear implantation in patients with advanced otosclerosis whose needs cannot be managed using the combination of stapes surgery and hearing aids. A controlled trial would provide evidence for its effectiveness and cost-effectiveness to healthcare commissioners...
May 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28538468/hearing-preservation-in-pediatric-cochlear-implantation
#5
Matthew L Carlson, Neil S Patel, Nicole M Tombers, Melissa D DeJong, Alyce I Breneman, Brian A Neff, Colin L W Driscoll
OBJECTIVE: Currently, there is a paucity of literature evaluating hearing preservation outcomes in children following cochlear implantation. The objective of the current study is to report pediatric hearing preservation results following cochlear implantation with conventional full-length electrodes. STUDY DESIGN: Retrospective review (2000-2016). SETTING: Tertiary referral center. PATIENTS: All pediatric patients with a ≤ 75 dB preoperative low-frequency pure tone average (LFPTA; 250-500 Hz average), who underwent cochlear implantation with a conventional length electrode...
May 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28538467/dichotic-listening-deficit-associated-with-solvent-exposure
#6
Simon P Landry, Adrian Fuente
HYPOTHESIS: A significant left ear deficit can be observed in solvent-exposed individuals using the dichotic digit test. BACKGROUND: Solvents are ubiquitous in global industrial processes. Due to their lipophilic nature, solvents can adversely affect large white matter tracks such as the corpus callosum. Previous investigations reveal that long-term workplace exposure to solvents is also deleterious to various auditory processes. Investigations in exposed populations suggest a decreased performance for dichotic listening...
May 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28538078/vibroplasty-in-severe-congenital-or-acquired-meatal-stenosis-by-coupling-an-active-middle-ear-implant-to-the-short-process-of-the-incus
#7
Jan Peter Thomas, Christiane Voelter, Katrin Neumann, Stefan Dazert
OBJECTIVE: To evaluate the safety and effectiveness of coupling an active middle ear implant to the short process of the incus in subjects with meatal pathologies. STUDY DESIGN: Retrospective study. SETTING: Tertiary referral center. PATIENTS: Twelve patients suffering from either congenital aural atresia or acquired meatal fibrosis. INTERVENTION: Implantation of an active middle ear implant with coupling of the actuator to the short process of the incus...
May 19, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28498272/paget-s-disease-of-the-temporal-bone-a-single-institution-contemporary-review-of-27-patients
#8
Nicholas L Deep, Jake G Besch-Stokes, John I Lane, Colin L W Driscoll, Matthew L Carlson
OBJECTIVES: To report a contemporary review from a single-institution series on Paget's disease of the temporal bone (PDTB). STUDY DESIGN: Retrospective chart review of patients evaluated from 1998 to 2016. SETTING: Quaternary referral center. PATIENTS: Patients with radiographically confirmed PDTB. MAIN OUTCOME MEASURES: Clinical, audiological, and radiological features and management strategies of PDTB...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28498271/epidemiology-of-dizzy-patient-population-in-a-neurotology-clinic-and-predictors-of-peripheral-etiology
#9
Thomas Muelleman, Matthew Shew, Rahul Subbarayan, Axel Shum, Kevin Sykes, Hinrich Staecker, James Lin
OBJECTIVE: To compare the proportion of peripheral versus nonperipheral dizziness etiologies among all patients, inclusive of those presenting primarily or as referrals, to rank diagnoses in order of frequency, to determine whether or not age and sex predict diagnosis, and to determine which subgroups tended to undergo formal vestibular testing. STUDY DESIGN: Retrospective cohort. SETTING: Academic neurotology clinic. PATIENTS: Age greater than 18 neurotology clinic patients with the chief complaint of dizziness...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28498270/age-related-increase-in-blood-levels-of-otolin-1-in-humans
#10
Ryan Tabtabai, Laura Haynes, George A Kuchel, Kourosh Parham
OBJECTIVE: To test the hypothesis that age-related demineralization of otoconia will result in an age-related increase in blood levels of otoconia matrix protein, otolin-1. STUDY DESIGN: Cross-sectional observational clinical trial. SETTING: Clinical research center. PATIENTS: Seventy nine men and women ranging in age from 22 to 95 years old. INTERVENTIONS: Diagnostic. MAIN OUTCOME MEASURES: Blood levels of otolin-1 in relation to age...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28498269/real-time-intracochlear-electrocochleography-obtained-directly-through-a-cochlear-implant
#11
Michael S Harris, William Jason Riggs, Kanthaiah Koka, Leonid M Litvak, Prashant Malhotra, Aaron C Moberly, Brendan P O'Connell, Jourdan Holder, Federico Alberto Di Lella, Carlos Mario Boccio, George B Wanna, Robert F Labadie, Oliver F Adunka
HYPOTHESIS: Utilizing the cochlear implant to record electrophysiologic responses during device placement is a feasible and efficacious technique for monitoring near real-time cochlear physiology during and following electrode insertion. BACKGROUND: Minimizing intracochlear trauma during cochlear implantation has emerged as a highly researched area to help improve patient performance. Currently, conventional cochlear implant technology allows for the recording of electrically evoked compound action potentials (eCAPs)...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28498268/transcanal-endoscopic-ear-surgery-for-excision-of-a-facial-nerve-venous-malformation-with-interposition-nerve-grafting-a-case-report
#12
Cameron C Wick, Mark Sakai, Timothy E Richardson, Brandon Isaacson
OBJECTIVE: To illustrate a novel approach for the surgical management of a venous malformation of the facial nerve, including interposition nerve grafting, via an exclusively transcanal endoscopic ear surgery (TEES) approach. PATIENT: Thirty nine-year-old woman with a preoperative House-Brackmann (HB) grade IV facial paresis secondary to a facial nerve tumor. INTERVENTION(S): Surgical excision and interposition nerve graft via a transcanal endoscopic approach...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28498267/endoscopic-infracochlear-approach-for-drainage-of-petrous-apex-cholesterol-granulomas-a-case-series
#13
Cameron C Wick, Alexander R Hansen, Joe Walter Kutz, Brandon Isaacson
OBJECTIVE: To describe the feasibility and technical nuances of a transcanal endoscopic infracochlear approach for drainage of petrous apex cholesterol granulomas. STUDY DESIGN: Retrospective case review. SETTING: Tertiary care university hospital. PATIENTS: A 32-year-old man with bilateral petrous apex cholesterol granulomas and a 54-year-old man with a left-sided petrous apex granuloma each with symptoms necessitating surgical intervention...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28498266/use-of-positive-airway-pressure-following-middle-ear-surgery-a-practice-survey-of-otologists
#14
Douglas S Ruhl, Anthony M Tolisano, Bradley W Kesser, George T Hashisaki, Macario Camacho
BACKGROUND: Positive airway pressure (PAP) devices are used as treatment for obstructive sleep apnea (OSA). PAP may increase middle ear pressure which is of interest to otologic surgeons. There is a lack of data to guide management of PAP therapy after middle ear surgery. OBJECTIVE: To elucidate how otologic surgeons manage PAP in their patients after ear surgery. STUDY DESIGN: A survey e-mailed to practicing members of the American Neurotology Society...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28498265/the-effect-of-systemic-steroid-on-hearing-preservation-after-cochlear-implantation-via-round-window-approach-a-guinea-pig-model
#15
Mun Young Chang, Yoon Chan Rah, Jun Jae Choi, Shin Wook Woo, Yu-Jung Hwang, Hayden Eastwood, Stephen J O'Leary, Jun Ho Lee
HYPOTHESIS: When administered perioperatively, systemic dexamethasone will reduce the hearing loss associated with cochlear implantation (CI) performed via the round window approach. BACKGROUND: The benefits of electroacoustic stimulation have led to interest in pharmacological interventions to preserve hearing after CI. METHODS: Thirty guinea pigs were randomly divided into three experimental groups: a control group; a 3-day infusion group; and a 7-day infusion group...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28498264/defining-the-hook-region-anatomy-of-the-guinea-pig-cochlea-for-modeling-of-inner-ear-surgery
#16
Jonathon Lo, Phillip Sale, Sudanthi Wijewickrema, Luke Campbell, Hayden Eastwood, Stephen John O'leary
HYPOTHESIS: The aim of this study was to describe the hook region anatomy of the guinea pig cochlea to identify the optimal surgical approach for cochlear implantation and to determine what anatomical structures are at risk. BACKGROUND: Animal studies investigating hearing loss after cochlear implantation surgery are currently constrained by the lack of a reproducible implantation model. METHODS: Guinea pig cochleae were imaged using thin-sheet laser imaging microscopy...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28498263/cochlear-implantation-in-patients-with-usher-syndrome-type-iia-increases-performance-and-quality-of-life
#17
Bas P Hartel, Josephine W I van Nierop, Wendy J Huinck, Liselotte J C Rotteveel, Emmanuel A M Mylanus, Ad F Snik, Henricus P M Kunst, Ronald J E Pennings
OBJECTIVES: Usher syndrome type IIa (USH2a) is characterized by congenital moderate to severe hearing impairment and retinitis pigmentosa. Hearing rehabilitation starts in early childhood with the application of hearing aids. In some patients with USH2a, severe progression of hearing impairment leads to insufficient speech intelligibility with hearing aids and issues with adequate communication and safety. Cochlear implantation (CI) is the next step in rehabilitation of such patients...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28481781/bone-anchored-hearing-implant-surgery-1-year-follow-up-data-shows-no-effect-of-hydroxyapatite-coating-on-soft-tissue-reaction-after-loading-at-1-week
#18
Morten Høgsbro, Andreas Agger, Lars Vendelbo Johansen
OBJECTIVE: To assess postoperative skin complications around a bone anchored hearing implant (BAHI) abutment coated with hydroxyapatite and loaded after 1 week. DESIGN: Single center, prospective cohort study of 25 adults with expected normal skin and bone quality. INTERVENTION: Implantation of the Baha BA400 hydroxyapatite coated implant system using a linear incision technique without soft tissue reduction. Abutments with lengths of 8 mm (n = 9), 10 mm (n = 11), and 12 mm (n = 5) were used...
May 5, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28481780/round-window-application-of-an-active-middle-ear-implant-a-comparison-with-hearing-aid-usage-in-japan
#19
Satoshi Iwasaki, Shin-Ichi Usami, Haruo Takahashi, Yukihiko Kanda, Tetsuya Tono, Katsumi Doi, Kozo Kumakawa, Kiyofumi Gyo, Yasushi Naito, Sho Kanzaki, Noboru Yamanaka, Kimitaka Kaga
OBJECTIVE: To report on the safety and efficacy of an investigational active middle ear implant (AMEI) in Japan, and to compare results to preoperative results with a hearing aid. DESIGN: Prospective study conducted in Japan in which 23 Japanese-speaking adults suffering from conductive or mixed hearing loss received a VIBRANT SOUNDBRIDGE with implantation at the round window. Postoperative thresholds, speech perception results (word recognition scores, speech reception thresholds, signal-to-noise ratio [SNR]), and quality of life questionnaires at 20 weeks were compared with preoperative results with all patients receiving the same, best available hearing aid (HA)...
May 5, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28475547/prediction-of-intraoperative-csf-gusher-and-postoperative-facial-nerve-stimulation-in-patients-with-cochleovestibular-malformations-undergoing-cochlear-implantation-surgery
#20
Teru Kamogashira, Shinichi Iwasaki, Akinori Kashio, Akinobu Kakigi, Shotaro Karino, Yu Matsumoto, Tatsuya Yamasoba
OBJECTIVE: To determine parameters in computed tomography (CT) of the temporal bone that would be useful for prediction of cerebrospinal fluid (CSF) gusher during cochlear implantation (CI) surgery and postoperative facial nerve stimulation (FNS) in patients with inner ear malformations. STUDY DESIGN: Retrospective study. SETTING: Tertiary referral center. PATIENTS: Three hundred seventy-five cases who had undergone CI surgery including 54 inner ear malformation cases were analyzed...
May 4, 2017: Otology & Neurotology
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