journal
MENU ▼
Read by QxMD icon Read
search

Otology & Neurotology

journal
https://www.readbyqxmd.com/read/28419064/the-application-of-next-generation-sequencing-for-mutation-detection-in-autosomal-dominant-hereditary-hearing-impairment
#1
Nicolas Gürtler, Benno Röthlisberger, Katja Ludin, Christoph Schlegel, Anil K Lalwani
OBJECTIVE: Identification of the causative mutation using next-generation sequencing in autosomal-dominant hereditary hearing impairment, as mutation analysis in hereditary hearing impairment by classic genetic methods, is hindered by the high heterogeneity of the disease. PATIENTS: Two Swiss families with autosomal-dominant hereditary hearing impairment. INTERVENTION: Amplified DNA libraries for next-generation sequencing were constructed from extracted genomic DNA, derived from peripheral blood, and enriched by a custom-made sequence capture library...
April 17, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28419063/the-effect-of-elevated-intracranial-pressure-on-frequency-tuning-of-air-conducted-ocular-vestibular-myogenic-potentials-in-m%C3%A3-ni%C3%A3-re-s-disease-patients
#2
Rebecca Maxwell, Claudia Jerin, Robert Gürkov
OBJECTIVE: To investigate the effect of increased intracranial pressure on ocular vestibular-evoked myogenic potential (oVEMP) amplitudes and frequency tuning in patients with Ménière's disease (MD) to elucidate whether oVEMPS recorded under such conditions could provide a simple and accurate diagnostic test for MD. SETTING: Tertiary referral center for otology and neurotology. PATIENTS: Ten patients with certain unilateral MD (mean age = 48...
April 17, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28419062/single-center-study-investigating-foreign-language-acquisition-at-school-in-children-adolescents-and-young-adults-with-uni-or-bilateral-cochlear-implants-in-the-swiss-german-population
#3
Renske Beeres-Scheenstra, Claudia Ohnsorg, Claudia Candreia, Sybille Heinzmann, Susana Castellanos, Nicola De Min, Thomas E Linder
OBJECTIVE: To evaluate foreign language acquisition at school in cochlear implant patients. STUDY DESIGN: Cohort study. SETTING: CI center. PATIENTS: Forty three cochlear implants (CI) patients (10-18 yr) were evaluated. CI nonusers and patients with CI-explantation, incomplete datasets, mental retardation, or concomitant medical disorders were excluded. INTERVENTION(S): Additional data (type of schooling, foreign language learning, and bilingualism) were obtained with questionnaires...
April 17, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28414694/ipsilesional-nystagmus-induced-by-vibration-in-subjects-with-m%C3%A3-ni%C3%A3-re-s-disease-or-vestibular-schwannoma
#4
María Fernanda Vargas Gamarra, Claudio Krstulovic, Vanesa Pérez Guillén, Herminio Pérez-Garrigues
OBJECTIVE: To analyze the frequency in which vibration-induced nystagmus (VIN) with ipsilesional direction appears in subjects with Ménière's disease (MD) or vestibular schwannoma (VS). STUDY DESIGN: Cross-sectional study. SETTING: Tertiary referral center. PATIENTS: Fifty-two subjects with MD and 21 subjects with vestibular schwannoma. INTERVENTION: Videonystagmographic recordings of VIN at 30, 60, and 100 Hz...
April 14, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28414693/systematic-review-on-the-trial-period-for-bone-conduction-devices-in-single-sided-deafness-rates-and-reasons-for-rejection
#5
Anne W Wendrich, Tiuri E Kroese, Jeroen P M Peters, Guido Cattani, Wilko Grolman
OBJECTIVE: To systematically review the literature to evaluate the trial period of bone conduction devices (BCDs) for adult patients with single-sided deafness (SSD). DATA SOURCES: The PubMed, Embase, and Cochrane Library databases were searched from their inception up to August 15, 2016 for SSD, BCD, and their synonyms. STUDY SELECTION: In total, 523 articles were retrieved, of which 12 satisfied the eligibility quality criteria. Our outcomes of interest were: 1) the BCD implantation rejection percentage, 2) reasons to reject BCD implantation, and 3) possible prognostic factors predicting the trial outcome...
April 14, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28414692/neuronal-fibers-and-neurotransmitter-receptor-expression-in-the-human-endolymphatic-sac
#6
Martin Nue Møller, Svend Kirkeby, Jonas Vikeså, Finn Cilius Nielsen, Per Cayé-Thomasen
INTRODUCTION: Recent studies suggest that the human endolymphatic sac (ES) may have multiple functions, including an ion-transport capacity comparable to the kidney, an immunological capacity and a possible natriuretic capacity. Further, there have been speculations of a yet undefined role in intracranial pressure homeostasis. The anatomical location towards the sigmoid sinus would suggest a possible endo- and/or paracrine signaling. However, neuronal connections may also apply, but it remains very scarcely explored in the human ES...
April 14, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28406848/clinical-validation-of-a-sound-processor-upgrade-in-direct-acoustic-cochlear-implant-subjects
#7
Eugen Kludt, Christiane D'hondt, Thomas Lenarz, Hannes Maier
OBJECTIVE: The objectives of the investigation were to evaluate the effect of a sound processor upgrade on the speech reception threshold in noise and to collect long-term safety and efficacy data after 2½ to 5 years of device use of direct acoustic cochlear implant (DACI) recipients. STUDY DESIGN: The study was designed as a mono-centric, prospective clinical trial. SETTING: Tertiary referral center. PATIENTS: Fifteen patients implanted with a direct acoustic cochlear implant...
April 14, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28414696/decrease-in-pneumococcal-otitis-media-cultures-with-concomitant-increased-antibiotic-susceptibility-in-the-pneumococcal-conjugate-vaccines-era
#8
Basel Jabarin, Jacob Pitaro, Tzilia Lazarovitch, Haim Gavriel, Limor Muallem-Kalmovich, Ephraim Eviatar, Tal Marom
OBJECTIVE: To study the change in the incidence and antibiotic susceptibility patterns of Streptococcus pneumoniae (Spn) in cultures obtained from children with otitis media (OM) during the pneumococcal conjugate vaccines (PCVs) era. STUDY DESIGN: Retrospective. SETTING: Secondary medical care center. PATIENTS: Children less than 8 years who presented with OM and had positive pneumococcal cultures during January 1, 2007 to December 12, 2014 were identified...
April 13, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28414695/imaging-criteria-to-predict-surgical-difficulties-during-stapes-surgery
#9
Claire Parra, Stéphanie Trunet, Benjamin Granger, Yann Nguyen, Georges Lamas, Daniele Bernardeschi, Rémi Hervochon, Frédéric Tankere
BACKGROUND AND PURPOSE: Stapes surgery for otosclerosis can be challenging if access to the oval window niche is restricted. The aim of this study was to determine the accuracy of the computed tomographic (CT) scan in the evaluation of anatomical distances, and to analyze its reliability in predicting surgical technical difficulties. MATERIAL AND METHODS: A total of 96 patients (101 ears) were enrolled in a prospective study between 2012 and May 2015. During surgery, we evaluated the distance D1 between the stapes and the facial nerve, distance D2 between the promontory and the facial nerve after ablation of the superstructure, and the intraoperative discomfort of the surgeon...
April 13, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28406851/in-reply-to-the-letter-to-the-editor-two-common-second-causes-of-dizziness-in-patients-with-m%C3%A3-ni%C3%A3-re-s-disease
#10
Babette F van Esch, Hester J van der Zaag-Loonen, Tjasse D Bruintjes, Peter Paul G van Benthem
No abstract text is available yet for this article.
April 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28406850/in-response-to-secondary-causes-of-dizziness-in-patients-with-m%C3%A3-ni%C3%A3-re-s-disease
#11
Hossein Mahboubi, Omid Moshtaghi, Kasra Ziai, Hamid R Djalilian
No abstract text is available yet for this article.
April 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28406849/current-management-practices-in-m%C3%A3-ni%C3%A3-re-s-disease
#12
Joseph W Clyde, Benjamin S Oberman, Huseyin Isildak
OBJECTIVE: To evaluate current trends in managing Ménière's disease (MD) by both general otolaryngologists and otologists/neurotologists and discuss treatment modalities. STUDY DESIGN: Cross-sectional study. SETTING: Survey of physicians. SUBJECTS AND METHODS: An electronic questionnaire was disseminated to all members of American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS). RESULTS: Eight hundred and sixty members replied for a response rate of 14...
April 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28394785/calculating-the-tumor-volumes-in-vestibular-schwannomas-are-the-abc-2-and-volumetric-methods-comparable
#13
Girish Bathla, Bruno Policeni, Marlan R Hansen, Kevin Berbaum
PURPOSE: To assess the efficacy of the ABC/2 method for calculating the volume of vestibular schwannomas as compared with 3-D planimetric method. STUDY DESIGN: Retrospective. METHODS: Fifty eight cases of pathologically confirmed sporadic vestibular schwannomas (VS) were analyzed. Tumors volumes were calculated for each tumor twice, once through semiautomated 3-D volumetric method and subsequently through ABC/2 (AP × ML × CC/2) methodology after calculating the maximal tumor dimensions in anteroposterior (AP), coronal (ML), and craniocaudal (CC) dimensions...
April 7, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28394784/igg4-related-sclerosing-disease-involving-middle-ear
#14
Ping Lu, Yan Sha, Feng Wang, Shuyi Wang
No abstract text is available yet for this article.
April 7, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28383465/emerging-therapies-for-sensorineural-hearing-loss
#15
Matthew Gordon Crowson, Ronna Hertzano, Debara L Tucci
OBJECTIVE: To critically review and evaluate the proposed mechanisms and documented results of the therapeutics currently in active clinical drug trials for the treatment of sensorineural hearing loss. DATA SOURCES: US National Institutes of Health (NIH) Clinical Trials registry, MEDLINE/PubMed. STUDY SELECTION & DATA EXTRACTION: A review of the NIH Clinical Trials registry identified candidate hearing loss therapies, and supporting publications were acquired from MEDLINE/PubMed...
April 5, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28383464/intra-and-interobserver-variability-of-cochlear-length-measurements-in-clinical-ct
#16
John E Iyaniwura, Mai Elfarnawany, Sadegh Riyahi-Alam, Manas Sharma, Zahra Kassam, Yves Bureau, Lorne S Parnes, Hanif M Ladak, Sumit K Agrawal
HYPOTHESIS: The cochlear A-value measurement exhibits significant inter- and intraobserver variability, and its accuracy is dependent on the visualization method in clinical computed tomography (CT) images of the cochlea. BACKGROUND: An accurate estimate of the cochlear duct length (CDL) can be used to determine electrode choice, and frequency map the cochlea based on the Greenwood equation. Studies have described estimating the CDL using a single A-value measurement, however the observer variability has not been assessed...
April 5, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28383463/influence-of-floating-mass-transducer-coupling-efficiency-for-active-middle-ear-implants-on-speech-recognition
#17
Alexander Müller, Parwis Mir-Salim, Nina Zellhuber, Ralf Helbig, Marc Bloching, Tobias Schmidt, Sven Koscielny, Oliver C Dziemba, Stefan K Plontke, Torsten Rahne
OBJECTIVE: The efficiency of vibroplasty (coupler-floating mass transducer [FMT] assembly) can be monitored by direct stimulation of the inner ear through the active middle-ear implant system and comparison of the vibroplasty in vivo threshold and the postoperative bone-conduction pure-tone threshold. The aim of this study was to compare the vibroplasty in vivo threshold with the postoperative speech recognition in patients with a high preoperative maximum word recognition score. STUDY DESIGN: Retrospective cohort study of German-speaking patients implanted with a vibrating ossicular prosthesis (VORP) 502 or VORP 503 and high preoperative maximum word recognition score between the years of 2011 and 2015...
April 5, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28379918/cost-effectiveness-of-pediatric-cochlear-implantation-in-rural-china
#18
Jianxin Qiu, Chongxian Yu, Thathya V Ariyaratne, Chris Foteff, Zhangmin Ke, Yi Sun, Li Zhang, Feifei Qin, Georgina Sanderson
OBJECTIVES: To evaluate the cost utility of cochlear implantation (CI) for severe to profound sensorineural hearing loss (SNHL) among children from rural settings in P.R. China (China). RESEARCH DESIGN: A cost-utility analysis (CUA) was undertaken using data generated from a single-center substudy of the Cochlear Pediatric Implanted Recipient Observational Study (Cochlear P-IROS). The data were projected over a 20-year time horizon using a decision tree model. SETTING: The Chinese healthcare payer and patient perspectives were adopted...
April 4, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28375939/audiological-results-in-ssd-with-an-active-transcutaneous-bone-conduction-implant-at-a-retrosigmoidal-position
#19
Rolf Salcher, Denise Zimmermann, Thomas Giere, Thomas Lenarz, Hannes Maier
OBJECTIVE: One option for patients with single sided deafness (SSD) who experience problems with insufficient hearing in different surroundings is the treatment with percutaneous bone-anchored hearing aids. Common medical problems associated to a skin penetrating abutment can be avoided by active transcutaneous bone conduction hearing implants. The purpose of our study was to evaluate the benefit of an active transcutaneous bone conduction hearing implant in patients with SSD. PATIENTS AND METHODS: Patients suffering from SSD who are implanted with an active transcutaneous bone conduction hearing implant in retrosigmoidal position were audiologically analyzed...
April 3, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28369007/drug-induced-defibrinogenation-as-new-treatment-approach-of-acute-hearing-loss-in-an-animal-model-for-inner-ear-vascular-impairment
#20
Bernhard G Weiss, Mattis Bertlich, Stephan A Bettag, Hendrik Desinger, Friedrich Ihler, Martin Canis
OBJECTIVE: Disturbance of cochlear microcirculation is considered to be the final common pathway of various inner ear diseases. Hyperfibrinogenemia causing increased plasma viscosity is a known risk factor for sudden sensorineural hearing loss and may lead to a critical reduction of cochlear blood flow. The aim of this study was to evaluate the effect of a substantial reduction of plasma fibrinogen levels by drug-induced defibrinogenation for the treatment of acute hearing loss in vivo...
March 31, 2017: Otology & Neurotology
journal
journal
35134
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"