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Kaohsiung Journal of Medical Sciences

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https://www.readbyqxmd.com/read/27847105/corrigendum-to-defining-risk-groups-of-patients-with-cancer-of-unknown-primary-site-and-cervical-nodal-metastases-by-f-18-fluorodeoxyglucose-positron-emission-tomography-and-computed-tomography-imaging-kaohsiung-j-med-sci-32-08-2016-407-413
#1
Yung-Yueh Su, Shih-Hsin Chen, Chia-Hsun Hsieh, Chun-Ta Liao, Chien-Yu Lin, Chung-Jan Kang, Tzu-Chen Yen
No abstract text is available yet for this article.
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27847104/discrepancy-of-abo-typing-in-acute-leukemia-patients
#2
LETTER
Shuo-Chun Ting, Panot Sainamthip, Hui-Hua Hsiao, Ta-Chih Liu
No abstract text is available yet for this article.
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27847103/undifferentiated-pancreatic-carcinoma-with-osteoclast-like-giant-cells-a-rare-entity-with-potential-misdiagnosis-of-a-gastrointestinal-stromal-tumor-on-preoperative-evaluation
#3
LETTER
Yen-Cheng Chen, Lin-An Chen, Chih-Hung Lin, Shen-Nien Wang
No abstract text is available yet for this article.
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27847102/influence-of-different-menstrual-phases-on-the-bispectral-index-during-dexmedetomidine-sedation
#4
Chao Han, Sheng-Jin Ge, Shao-Qiang Huang, Yao-Jun Lu, Ning Li
To investigate the influence of different menstrual phases on the Bispectral Index (BIS) during dexmedetomidine (Dex) sedation, 40 patients with regular menstrual cycle, American Society of Anesthesiologists I-II, aged 18-40 years, undergoing selective gynecologic laparoscopic surgery, were enrolled. According to different menstrual phases and the serum progesterone concentration, they were divided into two groups: the follicular phase group (Group F) and the luteal phase group (Group L), and each group had 20 patients...
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27847101/analysis-of-first-and-second-trimester-maternal-serum-analytes-for-the-prediction-of-morbidly-adherent-placenta-requiring-hysterectomy
#5
Efser Oztas, Sibel Ozler, Ali Turhan Caglar, Aykan Yucel
Morbidly adherent placenta (MAP) is a growing concern currently and is still a diagnostic challenge for obstetricians. As emergency hysterectomy due to unscheduled delivery in MAP carries significant risks, we aimed to evaluate whether first and second trimester serum analytes may be used in the prediction of MAP requiring hysterectomy. A retrospective chart review of all identified cases of placenta previa totalis with and without MAP was performed. A total of 316 pregnant women diagnosed as placenta previa totalis were identified and included in the analysis...
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27847100/thrombolytic-therapy-delay-is-independent-predictor-of-mortality-in-acute-pulmonary-embolism-at-emergency-service
#6
İnan Beydilli, Fevzi Yılmaz, Bedriye Müge Sönmez, Nalan Kozacı, Akar Yılmaz, İbrahim Halil Toksul, Ramazan Güven, Mustafa Avcı
Acute pulmonary embolism (PE) carries a high risk of morbidity and mortality. Delays in diagnosis or therapy may result in sudden, fatal deterioration; therefore, rapid diagnosis and an appropriate therapeutic approach are needed. We aimed to investigate the effect of delaying thrombolytic administration on the mortality rate in a suspected PE. We retrospectively analyzed 49 consecutive patients who were aged 18 years or older and received thrombolysis for a high-risk PE without a major contraindication. All patients were classified according to the time of onset of the thrombolytic therapy...
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27847099/efficacy-of-switching-therapy-of-luteinizing-hormone-releasing-hormone-analogue-for-advanced-prostate-cancer
#7
Yuan-Chi Shen, Chih-Hsiung Kang, Po-Hui Chiang
This study was conducted to determine the efficacy of switching therapy with a second-line luteinizing hormone-releasing hormone (LHRH) analogue after prostate-specific antigen (PSA) progression for advanced prostate cancer. We enrolled 200 patients, from December 2005 to September 2013, with nodal positive, metastatic prostate cancer or disease progression after definite treatment receiving continuous LHRH analogue therapy with monthly depot leuprorelin(sc) acetate 3.75 mg/vial (LA) or goserelin acetate(sc) 3...
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27847098/lamivudine-switch-therapy-in-chronic-hepatitis-b-patients-achieving-undetectable-hepatitis-b-virus-dna-after-3-years-of-entecavir-therapy-a-prospective-open-label-multicenter-study
#8
Ming-Lun Yeh, Ching-I Huang, Ming-Yen Hsieh, Chung-Feng Huang, Meng-Hsuan Hsieh, Jee-Fu Huang, Chia-Yen Dai, Zu-Yau Lin, Shinn-Chern Chen, Ming-Lung Yu, Wan-Long Chuang
The subsequent maintenance therapy in chronic hepatitis B (CHB) patients after long-term viral replication suppression is still uncertain. We aim to evaluate the efficacy of lamivudine (LAM) maintenance therapy in CHB patients achieving undetectable hepatitis B virus (HBV) DNA after 3 years of entecavir (ETV) therapy. Consecutive CHB patients who received at least 3 years of ETV and achieved HBV DNA negativity were allocated either LAM switch therapy or stopped ETV therapy in a prospective, open-label study...
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27847097/associations-of-caspase-3-gene-polymorphism-with-lumbar-disc-herniation
#9
Yi Fang, Jun Qiu, Zong-Bin Jiang, Sheng-Rong Xu, Zeng-Hua Zhou, Rui-Lin He
To investigate Caspase-3 gene polymorphisms (rs4647693 G/A, rs4647610 A/G, and rs12108497 T/C) and susceptibility to lumbar intervertebral disc herniation (LDH). The genotype frequency distributions of the polymorphisms were detected by polymerase chain reaction-restriction fragment length polymorphism in 107 LDH patients (case group) and 121 healthy individuals (control group). SHEsis software was used to conduct gene linkage disequilibrium and haplotype analysis. Regression analysis was used to analyze possible risk factors for LDH...
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27847096/a-cohort-study-on-10-year-survival-of-sporadic-medullary-thyroid-carcinoma-with-somatic-ret-mutation
#10
Li-Lun Chuang, Daw-Yang Hwang, Kun-Bow Tsai, Hon-Man Chan, Feng-Yu Chiang, Pi-Jung Hsiao
Somatic rearranged during transfection (RET) mutations are reported in 40-50% of sporadic medullary thyroid carcinoma (sMTC) patients with prognostic significance. As there is a lack of somatic RET mutations reported previously for the Taiwanese population, we tried to assess the presence of somatic RET mutations and evaluate the potential outcome predictors for our sMTC patients. We collected data from seven sMTC patients from the years 1997 to 2005 and analyzed their clinic-pathological features up to 2015...
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27847095/proteomic-analysis-and-translational-perspective-of-hepatocellular-carcinoma-identification-of-diagnostic-protein-biomarkers-by-an-onco-proteogenomics-approach
#11
REVIEW
Shyh-Horng Chiou, King-Teh Lee
Hepatocellular carcinoma (HCC) has been ranked as the third leading cause of cancer-related mortality worldwide. Typically, patients are already in advanced stages of liver cirrhosis at the time of HCC diagnosis. Because HCC is often detected at a late stage and is highly aggressive, noninvasive biomarkers are urgently needed for early diagnosis. Recent advances in gene-expression profiling technologies have enabled molecular classification of HCC into defined subclasses that provide a firm basis for further study of potential mechanisms and biomarkers underlying the development of HCC...
November 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27742039/left-ventricular-hypertrophy-a-rare-cardiac-involvement-of-becker-muscular-dystrophy
#12
Yu Kang, Yu-Cheng Chen, Qing Zhang
No abstract text is available yet for this article.
October 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27742038/tuberculosis-meningitis-in-patient-with-multiple-myeloma-during-bortezomib-containing-therapy
#13
Yu-Chen Tsai, Hui-Ching Wang, Hui-Hua Hsiao, Ta-Chih Liu
No abstract text is available yet for this article.
October 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27742037/hepatitis-d-virus-infections-among-injecting-drug-users-with-and-without-human-immunodeficiency-virus-infection-in-taiwan
#14
Meng-Hsuan Hsieh, Shu-Chi Wang, Ming-Yen Hsieh, Chung-Feng Huang, Ming-Lun Yeh, Jeng-Fu Yang, Ko Chang, Wei-Ru Lin, Chun-Yu Lin, Tun-Chieh Chen, Jee-Fu Huang, Chia-Yen Dai, Jih-Jin Tsai, Wan-Long Chuang, Ming-Lung Yu
In Taiwan, injecting drug use has been the main route of human immunodeficiency virus (HIV) transmission since 2005, with hepatitis B virus (HBV) and hepatitis D virus (HDV) also having similar transmission routes. This has now become an important public health issue. The aim of this study is to explore the conditions of HDV infections between injecting drug users (IDUs) with and without HIV infection in Southern Taiwan. In this study, 87 IDUs were enrolled, including 27 anti-HDV seronegative IDUs and 60 anti-HDV seropositive IDUs, and the results of their liver function tests, CD4 cell counts, and anti-HIV and HIV RNA levels were analyzed...
October 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27742036/percutaneous-cholecystostomy-for-acute-cholecystitis-in-high-risk-elderly-patients
#15
Wei-Chen Lin, Chen-Wang Chang, Cheng-Hsin Chu
Emergency cholecystectomy for acute cholecystitis (AC) is associated with high morbidity and mortality rates in elderly patients with significant comorbidities. The aim of this study was to evaluate percutaneous cholecystostomy for AC in elderly patients with various coexisting diseases. We retrospectively reviewed the records of 4311 patients with AC treated in Mackay Memorial Hospital between the years 2000 and 2015. The clinical course of AC was compared between nonelderly (age ≤70 years) and elderly patients (age>70 years)...
October 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27742035/impact-of-positive-surgical-margin-on-biochemical-recurrence-following-radical-prostatectomy-in-locally-advanced-prostate-cancer
#16
Cavit Ceylan, Senol Tonyali, Ibrahim Keles
This study aimed to determine the effect of surgical margin positivity on biochemical recurrence (BCR) in patients with locally advanced prostate cancer (PCa) who underwent radical retropubic prostatectomy (RRP). The medical records of all patients with locally advanced PCa that underwent RRP were retrospectively reviewed. Patient demographics, digital rectal examination findings, prostate biopsy Gleason score, prostate volume, pre- and post-treatment prostate-specific antigen (PSA) levels, definitive pathology Gleason score, surgical margin status, seminal vesicle invasion, perineural invasion, absence or presence of BCR, and the time to BCR were analyzed...
October 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27742034/significance-of-preoperative-neutrophil-lymphocyte-count-ratio-on-predicting-postoperative-sepsis-after-percutaneous-nephrolithotomy
#17
Volkan Sen, Ibrahim Halil Bozkurt, Ozgu Aydogdu, Tarik Yonguc, Serkan Yarimoglu, Pinar Sen, Omer Koras, Tansu Degirmenci
We evaluated the usefulness of preoperative neutrophil-lymphocyte count ratio (NLCR) in predicting postoperative sepsis after percutaneous nephrolithotomy (PCNL). In total, 487 patients who underwent PCNL for renal stones were included in the present retrospective study. The stone burden, number of tracts and location, operation time, fluoroscopy time, presence of residual stones, and blood transfusion rates were postoperatively recorded in all patients. All patients were followed up for signs of systemic inflammatory response syndrome (SIRS) and sepsis...
October 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27742033/detection-of-haemophilus-influenzae-type-b-streptococcus-agalactiae-streptococcus-pneumoniae-and-neisseria-meningitidis-in%C3%A2-csf%C3%A2-specimens-of-children-suspicious-of%C3%A2-meningitis-in-ahvaz-iran
#18
Mansour Amin, Mozhgan Ghaderpanah, Tahereh Navidifar
Meningitis is a life-threatening infection associated with a high mortality and morbidity worldwide. Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae are the most prevalent infectious agents that cause bacterial meningitis (BM). The objective of this study was to determine the frequencies of these three bacteria using bacterial cultures and polymerase chain reaction (PCR). In our cross-sectional study, cerebrospinal fluid (CSF) specimens were obtained from 196 patients who were suspected of having BM and referred to the pediatric ward of Abuzar Hospital (Ahvaz, Iran)...
October 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27742032/clinicopathological-features-and-pituitary-homeobox-1-gene-expression-in-the-progression-and-prognosis-of-cutaneous-malignant-melanoma
#19
Figen Barut, Perihan Udul, Furuzan Kokturk, Nilufer Onak Kandemir, Sevinc Hallac Keser, Sukru Oguz Ozdamar
The evidence that PITX1 (pituitary homeobox 1) is a significant tumor suppressor in human cancer remains largely circumstantial, but it clearly warrants further study as little is known about the tumor-inhibitory roles of PITX1 in cutaneous malignant melanoma. The aims of this study were to investigate PITX1 gene expression in patients with cutaneous malignant melanoma and to evaluate its potential relevance to clinicopathological characteristics and tumor cell proliferation. Clinicopathological findings of patients with cutaneous malignant melanoma were analyzed retrospectively...
October 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27742031/distinct-subpopulations-of-hepatitis-c-virus-infectious-cells-with-different-levels-of-intracellular-hepatitis-c-virus-core-protein
#20
Shu-Chi Wang, Jeng-Fu Yang, Chao-Ling Wang, Chung-Feng Huang, Yu-Yin Lin, Yi-You Chen, Chung-Ting Lo, Po-Yen Lee, Kuan-Ta Wu, Chia-I Lin, Meng-Hsuan Hsieh, Hung-Yi Chuang, Chi-Kung Ho, Ming-Lung Yu, Chia-Yen Dai
Chronic infection by hepatitis C virus (HCV) is a major risk factor for the development of hepatocellular carcinoma (HCC). Despite the clear clinical importance of virus-associated HCC, the underlying molecular mechanisms remain largely unclarified. Oxidative stress, in particular, DNA lesions associated with oxidative damage, plays a major role in carcinogenesis, and is strongly linked to the development of many cancers, including HCC. However, in identifying hepatocytes with HCV viral RNA, estimates of the median proportion of HCV-infected hepatocytes have been found as high as 40% in patients with chronic HCV infection...
October 2016: Kaohsiung Journal of Medical Sciences
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