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Kaohsiung Journal of Medical Sciences

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https://www.readbyqxmd.com/read/30173785/murine-typhus-associated-abducens-nerve-palsy
#1
LETTER
Lin Ting-Yang, Lin Shang-Yi, Chen Tun-Chieh
No abstract text is available yet for this article.
September 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30173784/central-retinal-vein-occlusion-associated-with-vemurafenib-use-in-metastatic-skin-melanoma
#2
LETTER
Shu-Yun Yang, San-Ni Chen
No abstract text is available yet for this article.
September 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30173783/stitch-guide-technique-for-bicanalicular-nasal-intubation-in-single-canalicular-laceration-reconstruction
#3
Ming-Jer Tsai, I-Wen Lin, Su-Shin Lee, Chung-Sheng Lai
Various surgical techniques for canalicular laceration reconstruction have been described in previous study. But there are still two difficult points which may take time in the operation even with the assistance of magnification. We present a simple and effective way to achieve the bicanalicular nasal intubation for the single canalicular laceration. From Jan 2005 to Dec 2015, 20 patients (21 eyes) with upper or lower canalicular laceration were treated with the Crawford lacrimal intubation set by this stitch guide method...
September 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30173782/metabolic-syndrome-and-vaspin-in-patients-with-bipolar-disorder
#4
Hulya Ertekin, Basak Sahin, Ali Metehan Caliskan, Ikbal Inanli, Yusuf Haydar Ertekin
Metabolic disorders and abnormal levels of circulating adipokines have been reported in patients with bipolar disorder (BD). The aim of this study was to investigate the differences in the correlations of vaspin plasma levels and metabolic parameters between two groups: patients with BD and mentally healthy persons. We measured plasma levels of vaspin, metabolic parameters, and metabolic syndrome (MS) in 101 patients with BD and 90 healthy control (HC) subjects. Patients with BD were evaluated with the Young Mania Rating Scale (YMRS) to assess manic symptoms and the Hamilton Depression Scale (HDS) to assess depressive symptoms...
September 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30173781/the-significance-of-the-initial-symptom-in-chinese-patients-with-upper-tract-urothelial-carcinoma-regular-health-examination-is-still-underutilized
#5
Dong Fang, Yan-Qing Gong, Nirmish Singla, Kun-Lin Yang, Geng-Yan Xiong, Lei Zhang, Xue-Song Li, Li-Qun Zhou
This paper is to elucidate the correlation between different symptoms of UTUC and the clinicopathological characteristics and prognosis. The clinicopathological data of 700 consecutive patients with UTUC who were treated with radical nephroureterectomy were reviewed, and symptoms were categorized into three groups: S1-no direct symptoms, S2-local symptoms (including hematuria and flank pain) and S3-systemic symptoms. We found that the distributions of patients in the S1, S2 and S3 groups were 96 (13.7%), 601 (85...
September 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30173780/downregulated-malat1-relates-to-recurrent-pregnancy-loss-via-sponging-mirnas
#6
Yan Wang, Hui-Ze Liu, Yang Liu, Hui-Juan Wang, Wen-Wen Pang, Jian-Jun Zhang
Recurrent pregnancy loss (RPL) is three or more times of consecutive spontaneous loss of pregnancy. The underlying cause is complicated and the etiology of over 50% of RPL patients is unclear. Metastasis associated lung adenocarcinoma transcript-1 (MALAT-1), a multiple lncRNA functions as key regulators of diverse cellular processes. In this study, we found a reduced MALAT1 level in the villus samples of 36 RPL patients. Predicted by bioinformatics tool and confirmed by dual luciferase assay, we identified that MALAT1 directly interacts with miRNAs...
September 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30173779/tumor-necrosis-factor-%C3%AE-mediated-pain-hypersensitivity-through-ret-receptor-in-resiniferatoxin-neuropathy
#7
Shui-Chin Lu, Ying-Shuang Chang, Hung-Wei Kan, Yu-Lin Hsieh
Neurogenic inflammation is an onset characteristic of small fiber neuropathy (SFN), which is attributed to neuropathic manifestations. Tumor necrosis factor-α (TNFα) is a cytokine that mainly mediates neurogenic inflammation through the ligand receptor TNF receptor 1 (TNFR1), and targeting TNFα/TNFR1 signaling is a direction toward treating inflammatory diseases and injury-induced neuropathy. However, the relationships between TNFα/TNFR1 signaling and Ret signaling, which mediates pain hypersensitivity, remains elusive...
September 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30173778/role-of-perk-eif2%C3%AE-signaling-pathway-in-fetal-male-rats-with-hypospadias-induced-by-di-n-butyl-phthalate
#8
Zhang Zhao, Guo-Chang Liu, Wen Fu
This study aims to explore the role of PERK-eIF2α signaling pathway in fetal male rats with hypospadias induced by maternal exposure to di-n-butyl phthalate (DBP). DBP was used to treat pregnant SD rats by gastric intubation from gestation day (GD) 14-18 to construct a hypospadias rat model. The amount, weight, anogenital distance (AGD), and hypospadias incidence of rats were recorded and the genital tubercle (GT) of fetal male rats was collected on GD 19. Western blotting was performed to detect the expressions of PERK-eIF2α pathway- and autophagy-related proteins, and cell apoptosis was detected using TUNEL method...
September 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30173777/mir-483-inhibits-colon-cancer-cell-proliferation-and-migration-by-targeting-traf1
#9
Zi-Yu Niu, Wen-Li Li, Da-Lei Jiang, Yan-Song Li, Xiang-Jun Xie
MicroRNAs are important regulators during human growth and development. Emerging evidence indicates that microRNAs play important roles in colorectal cancer. The aim of this study is to reveal the biological function and direct target gene of miR-483 in colorectal cancer. The biological function of miR-483 on the proliferation and migration of colon cancer cells was then examined by Edu assay and transwell assay, respectively. Our findings revealed that miR-483 mimic could significantly inhibit cell proliferation and migration...
September 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30041767/comment-on-genetic-diversity-of-multidrug-resistant-mycobacterium-tuberculosis-strains-isolated-from-tuberculosis-patients-in-iran-using-miru-vntr-technique
#10
LETTER
Masoud Keikha
No abstract text is available yet for this article.
August 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30041766/the-ophthalmologic-examination-of-children-with-juvenile-idiopathic-arthritis-should-be-emphasized-in-taiwan
#11
LETTER
Shu-Ruei Wu, Hsiao-Ching Kuo, Chiang-Yuan Wei, Bao-Ren Nong
No abstract text is available yet for this article.
August 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30041765/boredom-proneness-and-its-correlation-with-internet-addiction-and-internet-activities-in-adolescents-with-attention-deficit-hyperactivity-disorder
#12
Wen-Jiun Chou, Yu-Ping Chang, Cheng-Fang Yen
This study examined the associations of boredom proneness with Internet addiction and activities as well as the moderators for such associations in adolescents with attention-deficit/hyperactivity disorder (ADHD). In total, 300 adolescents with ADHD participated in this study. Their Internet addiction, the scores for lack of external and internal stimulation on the Boredom Proneness Scale-short form (BPS-SF), ADHD, parental characteristics, and the types of Internet activities were examined. The associations of boredom proneness with Internet addiction and Internet activities and the moderators of the associations were examined using logistic regression analyses...
August 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30041764/prostate-health-index-phi-improves-prostate-cancer-detection-at-initial-biopsy-in-taiwanese-men-with-psa-4-10-ng-ml
#13
Po-Fan Hsieh, Chao-Hsiang Chang, Chi-Rei Yang, Chi-Ping Huang, Wen-Chi Chen, Chin-Chung Yeh, Eric Chieh-Lung Chou, Kuo-Liang Chen, Chi-Shun Lien, Guang-Heng Chen, Po-Jen Hsiao, Yi-Huei Chang, Hsi-Chin Wu
In this study, we aimed to validate the Prostate Health Index (PHI) for the detection of prostate cancer (PCa). We prospectively enrolled patients aged 50-75 years with a serum prostate specific antigen (PSA) level of 4-10 ng/mL undergoing transrectal biopsy of the prostate between April 2016 and May 2017. The primary outcome was the diagnostic performance of various PSA derivatives (total PSA, free PSA, %fPSA, p2PSA, %p2PSA, and PHI) to predict PCa. The secondary outcome was comparisons of PSA derivatives between patients with a Gleason score (GS) ≤6 and GS ≥7...
August 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30041763/pre-treatment-with-proton-pump-inhibitors-decreases-the-success-of-primary-helicobacter-pylori-eradication-using-a-vonoprazan-based-regimen
#14
Satoshi Shinozaki, Hiroyuki Osawa, Hirotsugu Sakamoto, Yoshikazu Hayashi, Yasutoshi Kobayashi, Yoshimasa Miura, Alan Kawarai Lefor, Hironori Yamamoto
Vonoprazan-based regimens have improved the rate of successful Helicobacter pylori (H. pylori) eradication, but it has not reached 100%. The aim of this study is to clarify significant predictors of successful H. pylori eradication using a vonoprazan-based regimen. In this retrospective cohort study, 174 patients who underwent primary H. pylori eradication therapy were included. All patients underwent esophagogastroduodenoscopy before treatment. The vonoprazan-based regimen includes amoxicillin 750 mg, clarithromycin 200 mg and vonoprazan 20 mg twice daily for one week...
August 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30041762/effect-of-blood-purification-on-serum-mir-126-and-vegf-levels-in-the-process-of-atherosclerosis-in-uremic-patients-under-maintenance-hemodialysis
#15
Dong Zhao, Hong Shao
This study aims to study the influence of different blood purification approaches on the expression of miR-126 and VEGF serum levels in the development of atherosclerosis in uremic patients under maintenance hemodialysis (MHD). A total of 207 MHD patients with uremia were divided into HD (hemodialysis, n = 60), HDF (hemodiafiltration, n = 72), and HD + HP (hemodialysis + hemoperfusion, n = 75) groups based on different purification approaches. Eighty individuals who underwent physical examinations during the same period constituted the healthy controls...
August 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30041761/ultrasound-guided-intertumoral-injection-of-contrast-agents-combined-with-human-p53-gene-for-the-treatment-of-breast-cancer
#16
Jun-Cheng Guo, Yi-Jun Yang, Min Guo, Xiang-Ling Jiang
The objective of this study was to investigate the effects of ultrasound-guided injection of ultrasound contrast agents (UCAs) and the p53 gene on the treatment of rats with breast cancer (BC). Assembly of the p53 expression vector as well as that of a rat model with BC consisted of 200 successfully modeled rats randomly divided into 5 groups: p53 gene introduction, p53 gene introduction + ultrasound irradiation, p53 gene introduction + UCAs, p53 gene introduction + UCA + ultrasound irradiation, and UCA + ultrasound irradiation groups...
August 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30041760/neuroprotective-effect-of-tanshinone-iia-against-neuropathic-pain-in-diabetic-rats-through-the-nrf2-are-and-nf-%C3%AE%C2%BAb-signaling-pathways
#17
Fa-Bo Feng, Hai-Yan Qiu
The study aims to investigate whether tanshinone (TSN) IIA affects diabetic neuropathic pain (DNP) via the Nrf2/AR and NF-κB signaling pathways. Rats were randomly assigned into DNP group, TSN group (injected with TSN IIA), TSN + DRB group (injected with TSN IIA and 15 mg/kg Nrf2/ARE inhibitors), TSN + PDTC group (injected with TSN IIA and 60 mg/kg NF-κB inhibitors) or control group. The first four groups were successfully established as DNP models after injection of streptozotocin. The blood glucose level, mechanical withdrawal threshold (MWT), thermal withdrawal latency (TWL), nerve conduction velocity (NCV) and antioxidase level were detected...
August 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30041759/vitamin-d-and-its-role-in-breast-cancer
#18
REVIEW
Miriam de La Puente-Yagüe, Maria A Cuadrado-Cenzual, María J Ciudad-Cabañas, Marta Hernández-Cabria, Luis Collado-Yurrita
Vitamin D is a fat soluble vitamin that plays a role in calcium and phosphorus homeostasis. Recently, extensive research on its extraskeletal actions has linked vitamin D deficiency to an increased risk of infection, diabetes mellitus types 1 and 2, cardiovascular disease, obesity, asthma, inflammatory bowel disease, colon, breast, prostate and ovarian cancer and some neurological diseases. There are various mechanisms by which vitamin D influences the natural history of cancer. These include the role of vitamin D in the induction of apoptosis, stimulation of cell differentiation, anti-inflammatory and antiproliferative effects and inhibition of angiogenesis, invasion and metastasis...
August 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30063016/influence-of-tidal-volume-on-ventilation-distribution-and-oxygenation-during-one-lung-ventilation
#19
LETTER
Wei Wang, Mei-Ying Xu, Jing-Xiang Wu, Zhan-Qi Zhao
No abstract text is available yet for this article.
July 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30063015/simplified-scoring-system-for-prediction-of-mortality-in-acute-suppurative-cholangitis
#20
Barış Doğu Yıldız, Sabri Özden, Barış Saylam, Fahri Martlı, Mesut Tez
Our objective in this study was to identify the factors contributing to mortality in acute suppurative cholangitis which could be tested easily in every emergency clinic. This is a retrospective study enrolling 104 patients with acute suppurative cholangitis. Demographic and laboratory data were collected for analysis. In univariant analysis red cell distribution width, total bilirubin level, intensive care unit admission was identified as statistically significant (p < 0.05) to predict mortality. Three variables were statistically significant in multivariate analysis: total bilirubin level equal to or more than 6...
July 2018: Kaohsiung Journal of Medical Sciences
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