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Kaohsiung Journal of Medical Sciences

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https://www.readbyqxmd.com/read/30392574/hepatic-epithelioid-hemangioendothelioma-challenges-in-the-preoperative-diagnosis
#1
LETTER
Lan Zhang, Xin-Ju Chen, Jeong-Min Lee, Song-Shei Lin
No abstract text is available yet for this article.
November 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30392573/a-rare-pure-lymphoepithelioma-like-carcinoma-of-the-renal-pelvis-mimicking-upper-tract-urothelial-carcinoma-a-potential-diagnostic-pitfall
#2
LETTER
Yu-Chen Chen, Hao-Wei Chen, Kuang-Shun Chueh, Yu-Ching Wei
No abstract text is available yet for this article.
November 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30392572/prognostic-factors-of-patients-with-gastroenteropancreatic-neuroendocrine-neoplasms
#3
Pao-Yuan Huang, Kai-Lung Tsai, Chih-Ming Liang, Wei-Chen Tai, Kun-Ming Rau, Keng-Liang Wu, Chao-Cheng Huang, Seng-Kee Chuah
There is an increasing trend in the incidence of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) worldwide. The aim of the present study was to identify the prognostic factors of patients with GEP-NENs. A cross-sectional, retrospective chart review study was conducted among patients with pathologically proven GEP-NENs between January 2003 and December 2016 at Kaohsiung Chung-Gung Memorial Hospital. A total of 97 patients who met the inclusion criteria were included (male/female = 56/41, age: 57...
November 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30392571/early-functional-improvement-after-stroke-correlates-with-cardiovascular-fitness
#4
Chun-Kai Chen, Mao-Hsiung Huang, Wen-Lung Liang, Ruey-Tay Lin, Suh-Hang H Juo
Cardiovascular fitness exerts directly beneficial effects on functional and cognitive outcomes in patients of chronic stroke. However, the effect of early rehabilitation on cardiovascular function has not yet been thoroughly examined. We tested whether complementary rehabilitation program could influence cardiovascular fitness in an early stage of stroke patients. The associations for post-acute stroke functional recovery with cardiovascular fitness were explored. Thirty-seven patients with mean poststroke interval of 8...
November 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30392570/correlations-of-mmp-2-and-mmp-9-gene-polymorphisms-with-the-risk-of-hepatopulmonary-syndrome-in-cirrhotic-patients-a-case-control-study
#5
Jian-Wei Liu, Dong-Qiong Chen
Hepatopulmonary syndrome (HPS) increases the mortality of patients who suffered from liver cirrhosis, especially patients plagued by severe hypoxemia. Gene polymorphisms are reported to be related to the risk of HPS in cirrhotic patients. Thus, our study aims to elucidate the correlation between MMP-2 and MMP-9 gene polymorphisms and HPS in cirrhotic patients. A total of 152 cirrhotic patients suffering from HPS as well as another 152 cirrhotic patients without HPS were recruited. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was performed for MMP-2 and MMP-9 gene polymorphisms and logistic regression analysis for the relationship between clinicopathological features and HPS occurrence in cirrhotic patients...
November 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30392569/reduced-exosome-mir-425-and-mir-744-in-the-plasma-represents-the-progression-of-fibrosis-and-heart-failure
#6
Lu Wang, Jiao Liu, Bin Xu, Yu-Lan Liu, Zhou Liu
Heart failure creates a leading public health burden worldwide and cardiac fibrosis is a hallmark of pathological cardiac remodeling which was found in HF patients. In this study, we detected the expression of 9 candidate miRNAs in the plasma exosome samples from 31 HF patients, and found the level of miR-21, miR-425 and miR-744 was altered. The downregulation of miR-425 and miR-744 was also found in angiotensin II treated cardiac fibroblasts. Through functional study, we identified that the reduction of miR-425 and miR-744 relates to overexpression of collagen 1 and α-SMA, which result in fibrogenesis of cardiac fibroblasts...
November 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30392568/fatty-oil-from-securidaca-inappendiculata-exerted-therapeutic-effects-on-adjuvant-induced-arthritis-in-mice-via-suppression-on-fibroblast-like-synoviocyte
#7
Hui Jiang, Cong-Lan Ji, Kui Yang, Wen Zhang, Jian Zuo
Securidaca inappendiculata Hassk. (SI) is a medicinal plant used to treat rheumatoid arthritis (RA) in South China. A substantial amount of fatty oil was isolated from SI (SIF), however little knowledge about its chemical composition and medicinal potentials was obtained. In this study, we analyzed its chemical composition with methyl esterification based GC-MS method, and investigated the therapeutic potentials on adjuvant-induced arthritis (AA) in mice. MTT and western-blot methods were employed to investigate its effects on proliferation rate and protein expressions in MH7A cells, respectively...
November 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30392567/shrna-mediated-bmi-1-gene-silencing-inhibits-gastrointestinal-stromal-tumor-cell-telomerase-activity-and-enhances-apoptosis
#8
Xin Wang, Kun Wu, Lin-Kang Xiao, Xing-Ye Wu
Gastrointestinal stromal tumors (GISTs) are the most frequently occurring mesenchymal tumors of the gastrointestinal tract. Telomerase activity is well acknowledged as a critical factor in oncogenesis. The objective of the present study is to evaluate the effect of BMI gene silencing on proliferation, apoptosis and telomerase activity in human GIST882 cells. GIST882 cells were transfected with a eukaryotic expression vector of an shRNA fragment. The silencing efficiency in the GIST882 cells was determined by RT-qPCR and a western blot analysis...
November 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30392566/microrna-26b-suppresses-tumorigenicity-and-promotes-apoptosis-in-small-cell-lung-cancer-cells-by-targeting-myeloid-cell-leukemia-1-protein
#9
Jin-Guo Yu, Cheng-Hong Ji, Min-Hua Shi
The aim of this study was to investigate the role of microRNA-26b (miR-26b) in regulating the proliferation, migration, and apoptosis of small cell lung cancer (SCLC) cells. First, we examined the expression level of miR-26b in human normal fetal lung fibroblasts (NFLFs) and three SCLC cell lines NCI-H466, NCI-H1688, and NCI-H196. In the following experiments, the three SCLC cell lines were transfected with miR-26b mimic and inhibitor. Cell growth and survival, as well as migration and invasion capacities were determined by MTT, colony formation, Transwell migration and invasion, and wound healing assays...
November 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30309489/photopsia-an-unusual-manifestation-of-optic-chiasm-compression-by-sphenoid-sinus-chodorma
#10
LETTER
Yen-Chih Chen, Shin-Lin Chiu
No abstract text is available yet for this article.
October 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30309488/senior-l%C3%A3-ken-syndrome-with-iqcb1-mutation-in-taiwan
#11
LETTER
Pei-Hua Yu, Yuh-Ren Kuo, Janine Altmüller, Daw-Yang Hwang
No abstract text is available yet for this article.
October 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30309487/did-afp-l3-save-ultrasonography-in-community-screening
#12
Chih-Wei Yen, Yuan-Hung Kuo, Jing-Houng Wang, Kuo-Chin Chang, Kwong-Ming Kee, Shu-Feng Hung, Yi Chen, Lin-San Tsai, Shu-Chuan Chen, Chao-Hung Hung, Sheng-Nan Lu
In the community screening, those subjects with elevated serum alpha-fetoprotein (AFP) required further abdomen ultrasonography (US) to detect hepatocellular carcinoma (HCC). However, some chronic hepatitis patients might have elevated AFP. AFP-L3, has been proposed to differentiate HCC and hepatitis in elevated AFP cases in Japan for decades, but the utility is limited outside Japan. We conducted this study to elucidate the role of AFP-L3 in the community and the possibility of saving unnecessary US. A total of 56,702 subjects underwent a large-scale healthcare screening in Tainan county in 2004...
October 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30309486/influence-of-prostate-size-on-the-perioperative-and-postoperative-outcome-of-transurethral-plasmakinetic-enucleation-of-the-prostate-results-of-892-patients-with-3-years-of-follow-up
#13
Shu-Shang Chen, Mei-Jiao Lin, Ming-Fang Weng, Ling-Feng Zhu, Zhen Deng, Cheng-Yao Wu, Jin-Quan Cai, Wei-Zhen Wu, Jian-Ming Tan
To explore the influence of prostate size on the outcome of Plasmakinetic enucleation of the prostate (PkEP) for the treatment of benign prostate hyperplasia (BPH), The data of 892 patients with symptomatic BPH who underwent PkEP were retrospectively reviewed. Among them, 199 (22.31%) had the prostate size smaller than 40 g (Group 1), 409 (45.85%) between 40 and 79 g (Group 2), 197 (22.09%) between 80 and 120 g (Group 3), and 87 (9.75%) larger than 120 g (Group 4). Perioperative variables, perioperative and postoperative complications were recorded...
October 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30309485/prognostic-predictive-value-of-tlr4-polymorphisms-in-han-chinese-population-with-hypertrophic-cardiomyopathy
#14
Ke Han, Yan-Ping Li
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease and is an important cause of sudden death in patients of all ages. The aim of this study was to find out whether Toll-like receptor-4 (TLR4) polymorphism is associated with HCM. To explore the association between TLR4 gene polymorphisms and HCM, 486 HCM patients and 214 healthy controls were enrolled in a case-control study of Chinese Han population. Two single nucleotide polymorphisms (SNPs) in the promoter region of TLR4 gene, -728G > C (rs11536865) and -2081G > A (rs10983755), were genotyped by PCR restriction fragment length polymorphism (PCR-RFLP)...
October 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30309484/the-ghrelin-and-orexin-activity-in-testicular-tissues-of-patients-with-idiopathic-non-obstructive-azoospermia
#15
Seyma Ozkanli, Mehmet Murad Basar, Serkan Selimoglu, Bulent Erol, Oguz Ozkanli, Fuad Nurili, Semra Kahraman
The aim of the present study is to evaluate the presence of ghrelin and orexin in the testicular tissue of patients who have undergone microscopic testicular sperm extraction (micro-TESE) due to idiopathic non-obstructive azoospermia. Seventy azoospermic cases were included in this study; serum hormone levels were measured and genetic investigations were performed. The patients were divided into two groups: micro-TESE (+) and micro-TESE (-). The number of Leydig cells and stained cells in the seminiferous tubules were counted under a light microscope, and we analyzed ghrelin and orexin activity...
October 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30309483/microrna-21-is-upregulated-during-intestinal-barrier-dysfunction-induced-by-ischemia-reperfusion
#16
Lin Zhang, Feng Zhang, Dai-Kun He, Xiao-Ming Fan, Jie Shen
This study aimed to investigate the expression of miRNA-21 during intestinal barrier dysfunction induced by intestinal ischemia reperfusion. Forty SPF SD rats were divided into 5 groups randomly. Intestinal ischemia-reperfusion injury (IRI) was induced by mesenteric artery occlusion for 1 h and reperfusion for 1 h, and the rats were sacrificed at 1, 3, 6 and 12 h after reperfusion. Fresh intestine tissues were immediately isolated for the measurement of transepithelial electrical resistance (TER). The levels of cytokines, ICAM-1, DAO, iFABP and MPO in serum were determined by ELISA...
October 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30309482/lentiviral-mediated-microrna-26b-up-regulation-inhibits-proliferation-and-migration-of-hepatocellular-carcinoma-cells
#17
Chun-Zhong Lin, Rong-Wen Ou, Yu-Hai Hu
Hepatocellular carcinoma (HCC) is a frequently occurred malignancy worldwide with a high mortality. The treatment for HCC is still controversial. Emerging evidences have demonstrated that microRNAs (miRs) play a role in HCC. This study aims to investigate the effects of lentiviral-mediated miRNA-26b (miR-26b) on the proliferation and metastasis of HCC cells. The normal hepatic cell line HL-7702 and HCC cell lines HepG2 (without metastatic potential), SMMC-7721 (with low metastatic potential) and MHCC97H (with high metastatic potential) were purchased for our experiment...
October 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30309481/impaired-cutaneous-t-cell-attracting-chemokine-elevation-and-adipose-derived-stromal-cell-migration-in-a-high-glucose-environment-cause-poor-diabetic-wound-healing
#18
Wei-Ting Wang, Su-Shin Lee, Ya-Chin Wang, Ya-Wei Lai, Yur-Ren Kuo, Yueh-Bih Tang Chen, Yu-Sen Liu, Yi-Chia Wu
Diabetic wound care is a major health care concern. The major cause of non-healing of wounds in patients with diabetes mellitus (DM) patients mainly involves poor glycemic control, which hinders the migration of progenitor cells including mesenchymal stem cells to the wound site. In this study, we introduced adipose-derived stromal cells (ADSCs) into wound sites and demonstrated that the local transplantation of ADSCs accelerated DM-related wound healing. Furthermore, the migration ability of ADSCs, which diminishes in a high-glucose environment, was partially restored by the exogenous replenishment of the cutaneous T-cell attracting chemokine (CTACK/CCL27)...
October 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30173785/murine-typhus-associated-abducens-nerve-palsy
#19
LETTER
Lin Ting-Yang, Lin Shang-Yi, Chen Tun-Chieh
No abstract text is available yet for this article.
September 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/30173784/central-retinal-vein-occlusion-associated-with-vemurafenib-use-in-metastatic-skin-melanoma
#20
LETTER
Shu-Yun Yang, San-Ni Chen
No abstract text is available yet for this article.
September 2018: Kaohsiung Journal of Medical Sciences
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