Shun Deng, Enming Zhang, Yunyang Zhao, Hao Guo, Lan Luo, Song Yi, Bingxin Zheng, Xiaoyuan Mu, Kezhu Yuan, Xuangen Deng, Haibo Rong, Yanbo Ma, Wanping Bian, Hai Shen
The emergence of graphene quantum dots (GQDs) expands the use of graphene derivatives in nanomedicine for its direct therapeutic applications in treating neurodegeneration, inflammation, metabolic dysfunction, and among others. Nevertheless, the biosafety assessment of GQDs remains deficient mostly because of the diverse surface characteristics of the nanoparticles. Our prior work demonstrated that GQDs can induce strong thigmotactic effects in zebrafish larvae over a wide range of concentrations, yet the underlying metabolic mechanisms remain largely unknown...
February 23, 2024: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP