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Neurological Sciences

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https://www.readbyqxmd.com/read/28730573/a-wavering-puff-of-smoke-a-rare-case-of-moyamoya-disease
#1
LETTER
Anna Scalise, Maria Elena Laino, Benedetto Petralia, Antonella Piani, Gian Luigi Gigli
No abstract text is available yet for this article.
July 20, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28730572/hypomagnesaemia-as-a-trigger-of-relapsing-non-alcoholic-wernicke-encephalopathy-a-case-report
#2
LETTER
Damiano Baroncini, Pietro Annovazzi, Giorgio Minonzio, Ivano Franzetti, Mauro Zaffaroni
No abstract text is available yet for this article.
July 20, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28726054/reply-to-the-complex-interrelations-between-two-paroxysmal-disorders-headache-and-epilepsy
#3
LETTER
Pasquale Parisi, Pasquale Striano, Vincenzo Belcastro
No abstract text is available yet for this article.
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28726053/the-effect-of-different-ankle-and-knee-supports-on-balance-in-early-ambulation-of-post-stroke-hemiplegic-patients
#4
Burcu Talu, Zilan Bazancir
The purpose of this study was to compare the effects of different ankle and knee supports on balance in early ambulation of post-stroke hemiplegic patients. This is a randomized experimental study. The study sample included 20 hemiplegic patients who were able to stand with support and who had been diagnosed with a cerebrovascular accident within the last month. A knee immobilization brace (KIB) was first placed on each individual (first application), followed by placement of knee immobilizer brace and Foot Lifter Orthosis ® (FLO) (second application), and lastly, placement of KIB and rigid taping (RT) (third application)...
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28726052/transcranial-sonography-image-characteristics-in-different-parkinson-s-disease-subtypes
#5
Ai Yan Sheng, Ying Chun Zhang, Yu Jing Sheng, Cai Shan Wang, Ying Zhang, Hua Hu, Wei Feng Luo, CHun-Feng LIu
Recently, Parkinson's disease (PD) has been classified into three subtypes: postural instability gait difficulty (PIGD), tremor dominate (TD), and indeterminate PD. Transcranial sonography (TCS) is considered to be an important tool to diagnose PD. However, it is uncertain that whether there are differences in TCS image characteristics in different PD subtypes, so 373 idiopathic PD (188 PIGD, 108 TD, 77 indeterminate PD) were registered and received TCS in our investigation; also, the association between clinical characteristics and TCS results in different PD subtypes was analyzed...
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28726051/serum-methylmalonic-acid-correlates-with-neuropathic-pain-in-idiopathic-parkinson-s-disease
#6
Jin-Sung Park, Donghwi Park, Pan-Woo Ko, Kyunghun Kang, Ho-Won Lee
Recent studies have shown a relatively higher prevalence of peripheral neuropathy in idiopathic Parkinson's disease (IPD). The hypothesis is that prolonged levodopa exposure causes vitamin B12 deficiency, which leads to peripheral neuropathy. The aim of our study was to find the relationship between vitamin B12 and its precursor methylmalonic acid (MMA) in IPD patients with neuropathic pain. We performed a cross-sectional study by enrolling consecutive 43 patients who were clinically tested positive for F-18 FP-CIT PET and 15 patients were diagnosed with peripheral neuropathy according to the Toronto clinical scoring system (TCSS)...
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28726050/a-single-center-study-a%C3%AE-42-p-tau181-csf-ratio-to-discriminate-ad-from-ftd-in-clinical-setting
#7
Andrea Vergallo, Cecilia Carlesi, Cristina Pagni, Filippo Sean Giorgi, Filippo Baldacci, Lucia Petrozzi, Roberto Ceravolo, Gloria Tognoni, Gabriele Siciliano, Ubaldo Bonuccelli
Abnormal levels of beta amyloid (Aβ42) and tau protein concentrations in the cerebral spinal fluid (CSF) have been largely described in Alzheimer's disease (AD). Thus, CSF analysis of these biomarkers has been incorporated in recent AD diagnostic criteria, and it is increasingly performed for neurodegenerative dementia diagnostic workout in clinical setting. Nevertheless, the precise biomarkers CSF features in neurodegenerative dementia, either AD or Frontotemporal dementia (FTD), are still not fully clear today...
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28726049/quarterly-repeat-cycles-of-onabotulinumtoxina-in-chronic-migraine-patients-the-benefits-of-the-prolonged-treatment-on-the-continuous-responders-and-quality-of-life-conversion-rate-in-a-real-life-setting
#8
Antonio Santoro, Andrea Fontana, Anna M Miscio, Michele M Zarrelli, Massimiliano Copetti, Maurizio A Leone
OnabotulinumtoxinA was approved for treatment of chronic migraine (CM) after publication of Phase 3 Research Evaluating Migraine Prophylaxis Therapy (PREEMPT) trials. However, the PREEMPT trials lasted only up to 1 year. The main aim of our retrospective study was to evaluate whether a prolonged treatment of onabotulinumtoxinA (18 months, six quarterly cycles) will sustain or further improve the efficacy results and the quality of life achieved at 6 and 12 months. Patients were adults with CM with or without overuse of drugs, with at least six regularly repeat onabotulinumtoxinA treatments, administered according to the PREEMPT protocol...
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28726048/is-ct-perfusion-helpful-in-the-treatment-allocation-of-patients-with-acute-ischemic-stroke-an-expert-opinion-analysis
#9
Laura Strada, Jonathan Y Streifler, Bruno Del Sette, Matteo Puntoni, Antonio Castaldi, Daria Bianchini, Massimo Del Sette
BACKGROUND: Intravenous tPA is the standard treatment for acute ischemic stroke within 4.5 hours of symptom onset. Neuroradiological selection is currently based upon non-contrast- brain CT scan (NCCT). AIMS: To verify, in an "expert-opinion setting", the possible usefulness of CT perfusion (CTP) in decision-making toward i.v. thrombolysis. PATIENTS AND METHOD: One hundred and three consecutive patients with acute ischemic stroke who underwent NCCT and CTP were re-evaluated by an expert in cerebrovascular disease, to verify if adding CTP information would have changed expert's opinion...
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28710721/comments-on-camptocormia-as-presenting-in-lower-motor-neuron-disease-with-tardbp-mutation-case-report
#10
LETTER
Johnny Padulo, Andrea De Giorgio
No abstract text is available yet for this article.
July 14, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28707130/safety-and-efficacy-of-cerebrolysin-in-motor-function-recovery-after-stroke-a-meta-analysis-of-the-cars-trials
#11
Alla Guekht, Johannes Vester, Wolf-Dieter Heiss, Eugene Gusev, Volker Hoemberg, Volker W Rahlfs, Ovidiu Bajenaru, Bogdan O Popescu, Edith Doppler, Stefan Winter, Herbert Moessler, Dafin Muresanu
This meta-analysis combines the results of two identical stroke studies (CARS-1 and CARS-2) assessing efficacy of Cerebrolysin on motor recovery during early rehabilitation. Cerebrolysin is a parenterally administered neuropeptide preparation approved for the treatment of stroke. Both studies had a prospective, randomized, double-blind, placebo-controlled design. Treatment with 30 ml Cerebrolysin once daily for 3 weeks was started 24-72 h after stroke onset. In addition, patients participated in a standardized rehabilitation program for 21 days that was initiated within 72 h after stroke onset...
July 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28707129/neurosyphilis-combined-with-acute-anterior-thalamic-infarction
#12
LETTER
Jin San Lee, Hak Young Rhee, Sung Sang Yoon, Key-Chung Park
No abstract text is available yet for this article.
July 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28707128/thymectomy-is-a-beneficial-therapy-for-patients-with-non-thymomatous-ocular-myasthenia-gravis-a-systematic-review-and-meta-analysis
#13
Kai Zhu, Jiaoxing Li, Xin Huang, Wei Xu, Weibin Liu, Jiaxin Chen, Pei Chen, Huiyu Feng
Ocular myasthenia gravis, an autoimmune disease, is characterized by extraocular muscle weakness. Myasthenia gravis is closely associated with the functional status of the thymus gland. The efficacy of thymectomy for non-thymomatous ocular myasthenia gravis remains controversial. Here, we present the first systematic review and meta-analysis of studies assessing the outcome of thymectomy in patients with non-thymomatous ocular myasthenia gravis and found that the pooled rate of complete stable remission was 0...
July 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28699105/tapentadol-in-neuropathic-pain-cancer-patients-a-prospective-open-label-study
#14
Edvina Galiè, Veronica Villani, Irene Terrenato, Andrea Pace
Many chemotherapy treatments induce peripheral neuropathy (CIPN). These patients often experience neuropathic pain (NP) that reduces the quality of life. The aim of this prospective, open label study was to evaluate the efficacy and tolerability of tapentadol (TP) in patients affected by CIPN. CIPN were consecutively enrolled in a prospective open label study at the Neuro-Oncology Unit of the Regina Elena National Cancer Institute in Rome. During the titration phase, each patient initially received doses of TP 50 mg twice a day...
July 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28699104/suprascapular-nerve-block-for-the-treatment-of-hemiplegic-shoulder-pain-in-patients-with-long-term-chronic-stroke-a-pilot-study
#15
Alessandro Picelli, Sara Bonazza, Davide Lobba, Massimo Parolini, Alvise Martini, Elena Chemello, Marialuisa Gandolfi, Enrico Polati, Nicola Smania, Vittorio Schweiger
Hemiplegic shoulder pain is the most common pain condition after stroke. Suprascapular nerve block is an effective treatment for shoulder pain. The aim of this pilot study was to evaluate the effects of suprascapular nerve block on pain intensity, spasticity, shoulder passive range of motion, and quality of life in long-term chronic stroke patients with hemiplegic shoulder pain. Ten chronic stroke patients (over 2 years from onset) with hemiplegic shoulder pain graded ≥30 mm on the Visual Analogue Scale underwent suprascapular nerve block injection with 1 mL of 40 mg/mL methylprednisolone and 10 mL 0...
July 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28689225/use-of-cell-phones-and-brain-tumors-a-true-association
#16
LETTER
S A R Mortazavi, Ghazal Mortazavi, S M J Mortazavi
No abstract text is available yet for this article.
July 8, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28687974/syne1-related-cerebellar-ataxia-presents-with-variable-phenotypes-in-a-consanguineous-family-from-turkey
#17
E Yucesan, Sibel A Ugur Iseri, B Bilgic, Z Gormez, B Bakir Gungor, A Sarac, O Ozdemir, M Sagiroglu, H Gurvit, H Hanagasi, U Ozbek
SYNE1 related autosomal recessive cerebellar ataxia type 1 (ARCA1) is a late-onset cerebellar ataxia with slow progression originally demonstrated in French-Canadian populations of Quebec, Canada. Nevertheless, recent studies on SYNE1 ataxia have conveyed the condition from a geographically limited pure cerebellar recessive ataxia to a complex multisystem phenotype that is relatively common on the global scale. To determine the underlying genetic cause of the ataxia phenotype in a consanguineous family from Turkey presenting with very slow progressive cerebellar symptoms including dysarthria, dysmetria, and gait ataxia, we performed SNP-based linkage analysis in the family along with whole exome sequencing (WES) in two affected siblings...
July 7, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28687973/effect-of-exercise-therapy-on-quality-of-life-of-patients-with-multiple-sclerosis-in-iran-a-systematic-review-and-meta-analysis
#18
REVIEW
Abolhassan Afkar, Asieh Ashouri, Marjan Rahmani, Abdolhosein Emami Sigaroudi
Multiple sclerosis (MS) is a chronic and progressive disease charachterized by disabilities which adversely affect individuals' quality of life (QOL). In the present study, the effect size of exercise therapy on patients' QOL in both physical and mental dimensions were investigated and the moderator effect of a number of selected theoretical and significant practical variables were assessed. Relevant studies, published before July 2015, were identified by searching PubMed, Scopus, Google scholar, and Persian medical databases including IranMedex, Irandoc, Magiran, Scientific Information Database (SID), and Medlib...
July 7, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28687972/hypersomnia-hiding-a-bipolar-disorder
#19
LETTER
Martino Iolanda, Antonella Bruni, Maria Grazia Vaccaro, Michele Trimboli, Giuseppe Borzì, Pasquale De Fazio, Angelo Labate
No abstract text is available yet for this article.
July 7, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28685189/mesencephalic-astrocyte-derived-neurotrophic-factor-and-its-role-in-nervous-system-disease
#20
REVIEW
Zhu Li-Na, Chen Deng, Xu Da, Chen Si-Han, Wang Hai-Jiao, Liu Ling
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a member of the novel evolutionary conserved neurotrophic factor (NTF) family. MANF has a unique structure and an unparalleled dual mode of action that differs from other known NTFs. Recent studies have shown that MANF protects cells from endoplasmic reticulum stress. In addition, an increasing number of studies have found MANF plays an important role in nervous system disease. This review focuses on MANF, summarizing its unique structure, potential signaling pathway, and role in neurological disease...
July 6, 2017: Neurological Sciences
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