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Neurological Sciences

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https://www.readbyqxmd.com/read/28508989/evaluation-of-inner-retinal-layers-with-optic-coherence-tomography-in-vigabatrin-exposed-patients
#1
Betül Tuğcu, Mesrure Köseoğlu Bitnel, Fatma Selin Kaya, Betül Tekin Güveli, Dilek Ataklı
In order to reveal the underlying retinal pathology leading to dysfunction in vigabatrin-exposed patients, we aimed to evaluate the inner retinal layers encompassing ganglion cell complex (GCC) layer and inner plexiform layer with new generation optic coherence tomography (OCT). Fourteen patients with epilepsy and exposure to vigabatrin and 12 clinically normal individuals, constituting the control group, were included. Retinal images were obtained using spectral-domain OCT (Optovue RTVue Fourier domain). Nasal and superior quadrants of retinal nerve fiber layer (RNFL) were found to be significantly lower in the patient group compared to the controls (p < 0...
May 16, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28508988/guillain-barr%C3%A3-syndrome-variant-with-facial-diplegia-and-paresthesias-after-reactivation-of-varicella-zoster-virus
#2
LETTER
Xiaodong Chen, Ying Wang, Yongjun Cao
No abstract text is available yet for this article.
May 16, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28502059/dynamics-of-change-in-self-reported-disability-among-persons-with-parkinson-s-disease-after-2%C3%A2-years-of-follow-up
#3
Tatjana Gazibara, Darija Kisic-Tepavcevic, Marina Svetel, Aleksandra Tomic, Iva Stankovic, Vladimir Kostic, Tatjana Pekmezovic
Symptoms of Parkinson's disease (PD) progress over time causing significant disability. Yet, change in disability over shorter time periods has not been entirely understood. The purpose of this study was to assess the Self-Assessment Disability Scale (SADS) in persons with Parkinson's disease (PD) after 2 years of follow-up and compare it with the score observed at baseline. Additionally, we aimed at evaluating association of motor and non-motor PD features at baseline with a higher disability after 2 years of follow-up...
May 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28502058/reversible-cerebral-vasoconstriction-syndrome-and-antivitamin-k-anticoagulation-challenges-of-an-unusual-association
#4
LETTER
Amina Nasri, Malek Mansour, Amel Kacem, Jamel Zaouali, Ridha Mrissa
No abstract text is available yet for this article.
May 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28502057/microrna-125b-in-peripheral-blood-a-potential-biomarker-for-severity-and-prognosis-of-children-with-viral-encephalitis
#5
Qin-Ling Gao, Yun-Xia Ma, Da-Wei Yuan, Qing-Cai Zhang, Jun Zeng, Hao Li
This study aims to evaluate the effect of peripheral blood miR-125b expression on severity and prognosis in children with viral encephalitis (VE). Children with VE (severe and mild groups) were grouped into VE group, and 40 healthy children as control group. Plasma RNA was extracted, and real-time quantitative PCR was conducted to detect miR-125b relative expression. Associations of miR-125b expression with clinical characteristics and prognosis of VE children were analyzed. Area under ROC curve (AUC) was calculated to evaluate the accuracy of the prognostic value of miR-125b...
May 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28500446/a-portuguese-rapid-onset-dystonia-parkinsonism-case-with-atypical-features
#6
LETTER
Ana Luísa Sousa, Isabel Alonso, Marina Magalhães
No abstract text is available yet for this article.
May 12, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28497313/lewis-p-rowland-md
#7
(no author information available yet)
No abstract text is available yet for this article.
May 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28497312/phenytoin-neuroprotection-or-neurotoxicity
#8
REVIEW
Jan M Keppel Hesselink, David J Kopsky
Phenytoin is an 80-year young molecule and new indications are still emerging. The neuroprotective potential of phenytoin has been evaluated for decades. Recently, a positive phase II trial supported its further development in the treatment of optic neuritis in multiple sclerosis. In 1942, however, peripheral neuritis was first reported to be an adverse event of phenytoin, and since then a small but steady stream of publications discussed peripheral polyneuropathy as being a possible adverse event of phenytoin...
May 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28497311/circulating-tnf-%C3%AE-levels-increased-and-correlated-negatively-with-igf-i-in-postoperative-cognitive-dysfunction
#9
Jue Jiang, Xiang Lv, Bing Liang, Hong Jiang
Signaling pathways of tumor necrosis factor-α (TNF-α) and insulin-like growth factor-I (IGF-I) are found to be functionally interrelated in some experimental studies. IGF-I may be involved in the pathogenesis of postoperative cognitive dysfunction (POCD). In order to investigate the possible interaction of TNF-α and IGF-I in POCD, the plasma levels of IGF-I and TNF-α were determined in 44 patients under general anesthesia. As compared with non-POCD patients, POCD patients showed increased TNF-α and decreased IGF-I levels in plasma, as well as a significant negative correlation between TNF-α and IGF-I values...
May 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28497310/use-of-cell-phones-and-brain-tumors-a-true-association
#10
EDITORIAL
Ettore Beghi
No abstract text is available yet for this article.
May 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28497309/the-correlation-of-lymphocyte-subsets-natural-killer-cell-and-parkinson-s-disease-a-meta-analysis
#11
REVIEW
Sen Jiang, Hua Gao, Qin Luo, Pengfei Wang, Xinling Yang
The correlation between immunity and Parkinson's disease was presented in many papers, which also discussed lymphocyte and natural killer cell. But these studies have yielded inconsistent results. To systematically review the relationship between the lymphocyte subsets/natural killer cell and the risk of Parkinson's disease, we electronically searched the SpringerLink, Web of Science, Ebsco-medline with full text, Pubmed, Elsevier-ScienceDirect, Ovid-lww-oup, Wanfang Data for case-control trials on comparing the number of peripheral blood lymphocyte subsets and natural killer cell in Parkinson's patients and healthy controls...
May 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28497308/transient-abducens-nerve-palsy-after-cervical-traction
#12
LETTER
Bang-Hoon Cho, Hwan Heo, Sang-Woo Park, Seung-Han Lee
No abstract text is available yet for this article.
May 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28497307/highlights-of-the-issue-5-2017
#13
(no author information available yet)
No abstract text is available yet for this article.
May 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28488158/negative-impact-of-high-cumulative-glucocorticoid-dose-on-bone-metabolism-of-patients-with-myasthenia-gravis
#14
Nayara Felicidade Tomaz Braz, Natalia Pessoa Rocha, Érica Leandro Marciano Vieira, Rodrigo Santiago Gomez, Izabela Guimarães Barbosa, Olívio Brito Malheiro, Adriana Maria Kakehasi, Antonio Lucio Teixeira
This current study aimed to evaluate the frequency of low bone mass, osteopenia, and osteoporosis in patients with myasthenia gravis (MG) and to investigate the possible association between bone mineral density (BMD) and plasma levels of bone metabolism markers. Eighty patients with MG and 62 controls BMD were measured in the right femoral neck and lumbar spine by dual-energy X-ray absorptiometry. Plasma concentrations of osteocalcin, osteopontin, osteoprotegerin, tumor necrosis factor (TNF-α), interleukin (IL)-1β, IL-6, dickkopf (DKK-1), sclerostin, insulin, leptin, adrenocorticotropic hormone, parathyroid hormone, and fibroblast growth factor (FGF-23) were analyzed by Luminex®...
May 9, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28484881/quality-of-sleep-in-patients-receiving-androgen-deprivation-therapy-for-prostate-cancer
#15
Asli Koskderelioglu, Muhtesem Gedizlioglu, Yasin Ceylan, Bulent Gunlusoy, Nilden Kahyaoglu
Androgen deprivation is a therapeutic option for patients with prostate cancer (PC). However, it has negative effects on sleep quality and psychological condition. Here, we evaluated the appearance of sleep disturbances in patients on androgen deprivation therapy (ADT). We administered Pittsburgh Sleep Quality Index (PSQI), Beck Depression Inventory (BDI), Epworth Sleepiness Scale (ESS), and Fatigue Severity Scale (FSS) to consecutive prostate cancer patients who had undergone radical prostatectomy and are presently either under adjuvant ADT or followed in an unmedicated program (non-ADT)...
May 8, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28478498/management-of-intrathecal-baclofen-therapy-for-severe-acquired-brain-injury-consensus-and-recommendations-for-good-clinical-practice
#16
Antonio De Tanti, Federico Scarponi, Michele Bertoni, Giulio Gasperini, Bernardo Lanzillo, Franco Molteni, Federico Posteraro, Dino Francesco Vitale, Mauro Zanpolini
Although widespread in the treatment of generalised spasticity due to severe acquired brain injury, clinical use of intrathecal baclofen administered through an implanted catheter is not yet supported by full scientific evidence. The aim of the study is to provide recommendations for good clinical practice regarding intrathecal baclofen therapy. We used a modified RAND Delphi method to develop consensus-based medical guidelines, involving clinicians who use intrathecal baclofen therapy throughout Italy. The clinicians were asked 38 questions grouped in six areas (patient selection, contraindications for implant, tests prior to implant, method of implant and management of therapy, efficacy evaluation and goal setting, and management of complications)...
May 6, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28478497/can-both-normal-and-mildly-abnormal-albuminuria-and-glomerular-filtration-rate-be-a-danger-signal-for-diabetic-peripheral-neuropathy-in-type-2-diabetes-mellitus
#17
Yongze Zhang, Ying Jiang, Ximei Shen, Sunjie Yan
We aimed to investigate the potential association between urinary albumin-to-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) and diabetic peripheral neuropathy (DPN). We were especially interested in the relationship between normal or mildly abnormal UACR and eGFR with DPN. A retrospective study was performed in 1059 patients with type 2 diabetes patients from Fuzhou, China, who were seen between 2010 and 2015. The DPN population demonstrated higher UACR and lower eGFR than the non-DPN population...
May 6, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28478496/shifting-from-constant-voltage-to-constant-current-in-parkinson-s-disease-patients-with-chronic-stimulation
#18
P Amami, M M Mascia, A Franzini, F Saba, A Albanese
The study aimed to evaluate safety and efficacy of shifting stimulation settings from constant-voltage (CV) to constant-current (CC) programming in patients with Parkinson's disease (PD) and chronic subthalamic nucleus deep brain stimulation (STN DBS). Twenty PD patients with chronic STN DBS set in CV programming were shifted to CC and followed for 3 months; the other stimulation settings and the medication regimen remained unchanged. Side effects, motor, non-motor, executive functions, and impedance were assessed at baseline and during follow-up...
May 6, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28478495/persistence-of-anti-nmdar-antibodies-in-csf-after-recovery-from-autoimmune-encephalitis
#19
LETTER
S Mariotto, F Andreetta, A Farinazzo, S Monaco, S Ferrari
No abstract text is available yet for this article.
May 6, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28478494/the-impact-on-cognitive-functions-of-patients-with-pituitary-adenoma-before-and-after-surgery
#20
Xianxiang Wang, Xuanxia Tong, Yanfeng Zou, Xuefeng Tian, Zhongxiang Mao, Zhongwu Sun
Patients with pituitary adenoma have often suffered cognitive impairment. The study aims to identify the factors, and their impact, that affect the cognitive functions of pituitary adenoma patients. Seventy-six patients with pituitary adenoma were recruited, together with 76 healthy subjects as control. Patients (34 functioning and 42 non-functioning) were randomly assigned into either microscopic (n = 44) or neural endoscopic (n = 32) group. All surgeries were performed through single-nostril transsphenoidal approach under general anesthesia with endotracheal intubation...
May 6, 2017: Neurological Sciences
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