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Neurological Sciences

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https://www.readbyqxmd.com/read/29238910/jaw-clonus-in-motor-neuron-disease-an-interesting-case-and-review-of-literature
#1
LETTER
Tabish A Saifee, Antonella Macerollo
No abstract text is available yet for this article.
December 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29236190/as-the-first-sign-of-multiple-sclerosis-eight-and-a-half-syndrome
#2
LETTER
Selda Keskin Guler, Nalan Güneş, Burcu Gokce Cokal, Mustafa Yurtdaş, Tahır Yoldas
No abstract text is available yet for this article.
December 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29224058/systematic-assessment-and-characterization-of-chronic-pain-in-multiple-sclerosis-patients
#3
Diana Ferraro, Domenico Plantone, Franca Morselli, Giulia Dallari, Anna M Simone, Francesca Vitetta, Patrizia Sola, Guido Primiano, Viviana Nociti, Matteo Pardini, Massimiliano Mirabella, Catello Vollono
Pain is one of the most disabling clinical symptoms in patients with multiple sclerosis (MS). Several studies have already assessed the prevalence of pain in MS patients, reporting variable results, probably due to methodological differences. The aim of this single-centre cross-sectional study was to define the prevalence and characteristics of chronic pain in a population of MS patients using validated tools, and to analyse these data in relation to demographic and clinical features, including disease duration and disability (EDSS and its single functional system scores)...
December 9, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29214386/improvement-rate-of-patients-with-severe-brain-injury-during-post-acute-intensive-rehabilitation
#4
Rita Formisano, Marianna Contrada, Marta Aloisi, Maria Gabriella Buzzi, Paola Cicinelli, Cecilia Della Vedova, Letizia Laurenza, Maria Matteis, Francesca Spanedda, Vincenzo Vinicola, Marco Iosa
Patients with severe acquired brain injury (SABI) may evolve towards different outcomes. The primary aim was to evaluate the clinical evolution of a large population of patients with SABI admitted to post-acute rehabilitation from 2001 to 2016, diagnosed with severe brain injury (GCS ≤ 8) in the acute phase and a coma duration of at least 24 h. The possible changes between the admission time to a post-acute rehabilitation hospital and the discharge time were measured by means of Glasgow Outcome Scale (GOS), Level of Cognitive Functioning (LCF), and Disability Rating Scale (DRS)...
December 6, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29209905/primary-central-nervous-system-lymphoma-in-an-immunocompetent-patient-an-unusual-case-of-prolonged-response-to-steroids
#5
LETTER
Michele Pistacchi, Manuela Gioulis, Flavio Sanson, Giovanna Di Palma, Sandro Zambito Marsala
No abstract text is available yet for this article.
December 5, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29209904/association-of-variants-in-microrna-with-parkinson-s-disease-in-chinese-han-population
#6
Fang Li, Han Liu, Yuan Cheng, Jing Yang, Yutao Liu, Yanlin Wang, Zhihua Yang, Changhe Shi, Yuming Xu
MicroRNAs (miRNAs) are short RNAs regulating gene expression and may participate in pathogenesis of various diseases. Recently, rs897984:T > C in miR-4519 and rs11651671:A > G in miR-548at-5p have been reported that associate with Parkinson's disease (PD). However, to our knowledge, there is no further evidence regarding this finding. Herein, we performed a case-control study of 546 PD patients and 550 healthy controls to genotype the two single-nucleotide polymorphisms (SNPs) to assess their associations with PD...
December 5, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29198043/the-diagnosis-of-dementias-a-practical-tool-not-to-miss-rare-causes
#7
Camilla Ferrari, Benedetta Nacmias, Sandro Sorbi
Dementia represents one of the most diffuse disorders of our Era. Alzheimer's disease is the principle cause of dementia worldwide. Metabolic, infectious, autoimmune, inflammatory, and genetic dementias represent a not negligible number of disorders, with increasing numbers in younger subjects. Due to the heterogeneity of patients and disorders, the diagnosis of dementia is challenging. In the present article, we propose a practical diagnostic approach following the two-step investigation procedure. The first step includes basic blood tests and brain neuroimaging, performed on all patients...
December 2, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29198042/seizure-as-the-unique-clinical-manifestation-of-cerebral-metastases-in-a-27-year-old-man-with-non-small-cell-lung-cancer
#8
LETTER
Rui-Juan Lv, Pu Yin, Qun Wang, Xiao-Qiu Shao
No abstract text is available yet for this article.
December 2, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29198041/ethical-considerations-on-novel-neuronal-interfaces
#9
Kadircan H Keskinbora, Kader Keskinbora
Wireless powered implants, each smaller than a grain of rice, have the potential to scan and stimulate brain cells. Further research may lead to next-generation brain-machine interfaces for controlling prosthetics, exoskeletons, and robots, as well as "electroceuticals" to treat disorders of the brain and body. In conditions that can be particularly alleviated with brain stimulation, the use of such mini devices may pose certain challenges. Health professionals are becoming increasingly more accountable in decision-making processes that have impacts on the life quality of individuals...
December 2, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29196955/simple-linear-brainstem-mri-measurements-in-the-differential-diagnosis-of-progressive-supranuclear-palsy-from-the-parkinsonian-variant-of-multiple-system-atrophy
#10
Vasilios C Constantinides, George P Paraskevas, Eleftherios Stamboulis, Elisabeth Kapaki
Differential diagnosis of progressive supranuclear palsy (PSP) and the parkinsonian variant of multiple system atrophy (MSA-P) from Parkinson's disease (PD) can be difficult, particularly in atypical cases or early in the disease course. The Magnetic Resonance Parkinsonism Index (MRPI) utilizes linear and surface (planimetry) measurements and has been proposed as a dual MRI biomarker, with high values indicative of PSP and low values of MSA. The aim of this study was to examine the utility of simple linear MRI brainstem measurements, without the use of MRI planimetry, in the diagnosis of patients with Parkinsonism and compare them to the MRPI...
December 1, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29188399/the-alcoholic-brain-neural-bases-of-impaired-reward-based-decision-making-in-alcohol-use-disorders
#11
Caterina Galandra, Gianpaolo Basso, Stefano Cappa, Nicola Canessa
Neuroeconomics is providing insights into the neural bases of decision-making in normal and pathological conditions. In the neuropsychiatric domain, this discipline investigates how abnormal functioning of neural systems associated with reward processing and cognitive control promotes different disorders, and whether such evidence may inform treatments. This endeavor is crucial when studying different types of addiction, which share a core promoting mechanism in the imbalance between impulsive subcortical neural signals associated with immediate pleasurable outcomes and inhibitory signals mediated by a prefrontal reflective system...
November 29, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29185135/disease-modifying-treatments-modulate-myeloid-cells-in-multiple-sclerosis-patients
#12
Gloria Dalla Costa, Annamaria Finardi, Livia Garzetti, Tiziana Carandini, Giancarlo Comi, Vittorio Martinelli, Roberto Furlan
The role of myeloid cells in the pathogenesis of MS is determined by the polarization they acquire after activation, and mediated by release of extracellular vesicles (MVs). We assessed the effects of treatments for MS on activation and polarization of myeloid cells. MVs levels and markers of polarization of myeloid cells have been assessed at baseline and up to 6 months after the start of a MS treatment. Patients had higher levels of MVs than controls, and these increased significantly over 6 months under natalizumab...
November 28, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29181655/the-organisation-of-the-acute-ischemic-stroke-management-key-notes-of-the-italian-neurological-society-and-of-the-italian-stroke-organization
#13
E Agostoni, A Carolei, G Micieli, L Provinciali, D Toni, Simone Vidale
The main aim of acute ischemic stroke treatment is the as much possible prompt, safe and effective arterial recanalisation, in order to restore reperfusion into the ischemic brain area. The procedures obtaining this result are rapidly evolving and in the last years, we observed new evidences that affirmed the therapeutical benefit of the concomitant treatment using endovenous thrombolysis and mechanical thrombectomy in selected patients with ischemic stroke. However, all treatments are time-sensitive and the main limitation for their application is represented by the time...
November 27, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29181654/diverse-clinical-presentations-of-neurosyphilis-focus-on-differential-diagnosis
#14
LETTER
Agnieszka Chrząszcz-Włodarczyk, Adam Włodarczyk, Joanna Szarmach
No abstract text is available yet for this article.
November 27, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29181653/acute-disseminated-encephalomyelitis-associated-with-debut-of-a-late-onset-coeliac-disease-a-case-report
#15
LETTER
Jonas Alexander Jarholm, Espen Saxhaug Kristoffersen, Christine Wohlleben, Svetozar Zarnovicky, Kashif Waqar Faiz
No abstract text is available yet for this article.
November 27, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29177794/imaging-of-the-thymus-in-myotonic-dystrophy-type-1
#16
Andrea Mignarri, Francesco Gentili, Francesco Masia, Angelo Genua, Silvia Cenciarelli, Paola Brunori, Maria Antonietta Mazzei, Alessandro Malandrini, Antonio Federico, Francesco Giuseppe Mazzei, Maria Teresa Dotti
The occurrence of thymoma in myotonic dystrophy type 1 (DM1) has been occasionally reported, and an increased risk of tumors has been observed. We performed imaging of the thymus in 22 patients carrying DMPK expansion. Clinical examination and routine instrumental exams were performed at the same time. We observed no thymic abnormalities in 13 subjects, thymic hyperplasia in eight patients, and an invasive thymoma in one case. Subjects with thymic abnormalities did not show peculiarities as regards clinical and electrophysiological features...
November 25, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29177793/steroid-induced-hyperglycemic-chorea-in-a-patient-without-diabetes-mellitus
#17
LETTER
Sun Min Lee, Je Hong Min, Jung Han Yoon
No abstract text is available yet for this article.
November 25, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29170849/myh7-mutation-associated-with-two-phenotypes-of-myopathy
#18
Nan Li, Zhe Zhao, Hongrui Shen, Qi Bing, Xuan Guo, Jing Hu
The mutations of MYH7 (slow skeletal/β-cardiac myosin heavy chain) are commonly found in familial hypertrophic/dilated cardiomyopathy, and also can cause Laing early-onset distal myopathy (LDM), myosin storage myopathy (MSM), and congenital myopathy with fiber-type disproportion (CFTD). Here we report two cases whose diagnosis was hereditary myopathy according to clinical feature and muscle pathology analysis. High-throughput genomic sequencing (next generation sequencing) was performed to validate the diagnosis...
November 24, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29170848/isolated-bilateral-internuclear-ophthalmoplegia-due-to-lacunar-infarction
#19
LETTER
Zhao Jiang, Wenhong Wang
No abstract text is available yet for this article.
November 23, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29170847/highlights-of-the-issue-12-2017
#20
(no author information available yet)
No abstract text is available yet for this article.
November 23, 2017: Neurological Sciences
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