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Veterinary Anaesthesia and Analgesia

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https://www.readbyqxmd.com/read/28583773/anesthetic-synergy-between-two-n-alkanes
#1
Robert J Brosnan, Fabíola B Fukushima, Trung L Pham
OBJECTIVE: N-butane and n-pentane can both produce general anesthesia. Both compounds potentiate γ-aminobutyric acid type A (GABAA) receptor function, but only butane inhibits N-methyl-d-aspartate (NMDA) receptors. It was hypothesized that butane and pentane would exhibit anesthetic synergy due to their different actions on ligand-gated ion channels. STUDY DESIGN: Prospective experimental study. ANIMALS: A total of four Xenopus laevis frogs and 43 Sprague-Dawley rats...
May 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28728945/clasper-flaring-in-a-guitarfish-zapteryx-brevirostris-elasmobranchii-rhinobatidae-under-anesthesia
#2
LETTER
Natascha Wosnick, Bianca S Rangel, Renan A Moreira, Carolina A Freire
No abstract text is available yet for this article.
April 17, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28693970/development-of-a-sedation-protocol-using-orally-administered-tiletamine-zolazepam-acepromazine-in-free-roaming-dogs
#3
Hsiao-Chun Huang, Shih-Wei Huang, Kuan-Hua Yu, Jiann-Hsiung Wang, Jui-Te Wu
OBJECTIVE: To investigate the sedative effects in dogs of tiletamine-zolazepam-acepromazine (TZA) or ketamine-flunitrazepam (KF) administered orally and to evaluate the effectiveness of encapsulated TZA for capturing free-roaming dogs. STUDY DESIGN: Experimental study followed by a field trial. ANIMALS: Six research dogs and 27 free-roaming dogs. METHODS: In a pilot study, six research dogs were administered liquid TZA (20 mg kg(-1) tiletamine-zolazepam and 2 mg kg(-1) acepromazine) or liquid KF (50 mg kg(-1) ketamine and 2 mg kg(-1) flunitrazepam) orally: treatment 1, forcefully squirting liquid medication into the mouth; treatment 2, encapsulating liquid medication for administration in canned food; treatment 3, administering liquid medication mixed with gravy...
April 14, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28687474/alfaxalone-for-maintenance-of-anaesthesia-in-ponies-undergoing-field-castration-continuous-infusion-compared-with-intravenous-boluses
#4
Julia Deutsch, Abel Ekiri, Annemarie de Vries
OBJECTIVE: To compare alfaxalone as continuous intravenous (IV) infusion with intermittent IV injections for maintenance of anaesthesia in ponies undergoing castration. STUDY DESIGN: Prospective, randomized, 'blinded' clinical study. ANIMALS: A group of 33 entire male Welsh ponies undergoing field castration. METHODS: After preanaesthetic medication with IV detomidine (10 μg kg(-1)) and butorphanol (0.05 mg kg(-1)), anaesthesia was induced with IV diazepam (0...
April 14, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28716684/a-comparison-of-retrobulbar-and-two-peribulbar-regional-anesthetic-techniques-in-dog-cadavers
#5
Yael Shilo-Benjamini, Peter J Pascoe, Erik R Wisner, Nili Kahane, Philip H Kass, David J Maggs
OBJECTIVE: To compare injectate distribution and likelihood of regional anesthesia to the orbit following retrobulbar (RB) or peribulbar (PB) injections in dog cadavers. STUDY DESIGN: Randomized, masked study. ANIMALS: Twenty-four dog cadavers (aged 5.5-17 years, 2.0-36.3 kg). METHODS: Orbits underwent one of three injection techniques with bupivacaine 0.5% and iohexol (1:1): ventrolateral RB injection (1-2 mL; 15 orbits), medial canthal PB injection (2-8 mL; PB-1; 16 orbits), or dorsomedial and ventrolateral PB injections (each 1-4 mL; PB-2; 16 orbits)...
April 13, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28663042/pharmacokinetics-of-dexmedetomidine-mk-467-and-their-combination-following-intramuscular-administration-in-male-cats
#6
Bruno H Pypendop, Juhana Honkavaara, Jan E Ilkiw
OBJECTIVE: To characterize the pharmacokinetics of dexmedetomidine, MK-467 and their combination following intramuscular (IM) administration to cats. STUDY DESIGN: Prospective randomized crossover experimental study. ANIMALS: A total of eight healthy adult male castrated cats aged 1-2 years. METHODS: Cats were administered dexmedetomidine (25 μg kg(-1)) IM (treatment D25IM) or intravenously (IV; treatment D25IV); MK-467 (600 μg kg(-1)) IM (treatment MK600IM) or IV (treatment MK600IV); or dexmedetomidine (25 μg kg(-1)) IM with 300, 600 or 1200 μg kg(-1) MK-467 IM (treatments D25MK300IM, D25MK600IM and D25MK1200IM)...
April 9, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28720393/maxillary-nerve-blocks-in-horses-an-experimental-comparison-of-surface-landmark-and-ultrasound-guided-techniques
#7
Stephanie Stauffer, Beckie Cordner, Jonathon Dixon, Thomas Witte
OBJECTIVE: The aim of this preliminary proof-of-concept study was to evaluate and compare the success and complication rate of infiltration of the maxillary nerve of cadaver heads using previously described surface landmarks, standard ultrasound and a novel needle guidance positioning ultrasound system (SonixGPS). STUDY DESIGN: Prospective, anatomical, method-comparison study. ANIMALS: Thirty-eight equine cadaver heads. METHODS: Twenty-six veterinary students performed the three methods consecutively on cadaver heads using an 18 gauge, 8...
April 6, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28716686/sedative-and-cardiovascular-effects-of-intranasal-or-intramuscular-dexmedetomidine-in-healthy-dogs
#8
Fabiana Micieli, Bruna Santangelo, Fabiana Reynaud, Alessandro Mirra, Giusy Napoleone, Giovanni Della Valle, Karine G Portier, Giancarlo Vesce
OBJECTIVE: To compare the clinical effects and sedation scores following either intranasal (IN) or intramuscular (IM) administration of dexmedetomidine in dogs. STUDY DESIGN: Prospective, blinded, randomized, clinical study. ANIMALS: A total of 20 client-owned dogs scheduled for noninvasive diagnostic procedures. METHODS: Dogs were allocated to be administered dexmedetomidine 0.02 mg kg(-1) IN (IN group) or IM (IM group)...
April 5, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28462846/effect-of-detomidine-or-romifidine-constant-rate-infusion-on-plasma-lactate-concentration-and-inhalant-requirements-during-isoflurane-anaesthesia-in-horses
#9
MChie Niimura Del Barrio, Rachel C Bennett, J M Lynne Hughes
OBJECTIVE: Influence of detomidine or romifidine constant rate infusion (CRI) on plasma lactate concentration and isoflurane requirements in horses undergoing elective surgery. STUDY DESIGN: Prospective, randomised, blinded, clinical trial. ANIMALS: A total of 24 adult healthy horses. METHODS: All horses were administered intramuscular acepromazine (0.02 mg kg(-1)) and either intravenous detomidine (0.02 mg kg(-1)) (group D), romifidine (0...
March 30, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28734854/pulse-pressure-variation-as-a-guide-for-volume-expansion-in-dogs-undergoing-orthopedic-surgery
#10
Denise T Fantoni, Keila K Ida, André M Gimenes, Matheus M Mantovani, Jacqueline R Castro, Geni C F Patrício, Aline M Ambrósio, Denise A Otsuki
OBJECTIVE: To investigate whether pulse pressure variation (PPV) can predict fluid responsiveness in healthy dogs during clinical surgery. STUDY DESIGN: Prospective clinical study. ANIMALS: Thirty-three isoflurane-anesthetized dogs with arterial hypotension during orthopedic surgery. METHODS: Fluid challenge with lactated Ringer's solution (15 mL kg(-1) in 15 minutes) was administered in mechanically ventilated dogs (tidal volume 10 mL kg(-1)) with hypotension [mean arterial pressure (MAP) < 65 mmHg]...
March 22, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28734853/the-impact-of-mk-467-on-sedation-heart-rate-and-arterial-blood-pressure-after-intramuscular-coadministration-with-dexmedetomidine-in-conscious-cats
#11
Juhana Honkavaara, Bruno Pypendop, Jan Ilkiw
OBJECTIVE: To study the effects of MK-467, a peripheral α2-adrenoceptor antagonist, on sedation, heart rate and blood pressure after intramuscular (IM) coadministration with 25 μg kg(-1) of dexmedetomidine in cats. STUDY DESIGN: Prospective, randomized, controlled, blinded, cross-over, experimental study. ANIMALS: A total of eight healthy, adult, neutered male cats. METHODS: Cats were administered five IM treatments at least 2 weeks apart, consisting of dexmedetomidine 25 μg kg(-1) (D25), MK-467 600 μg kg(-1) (M600) and D25 combined with 300, 600 and 1200 μg kg(-1) of MK-467 (D25M300, D25M600 and D25M1200, respectively)...
March 22, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28733106/haemodynamic-changes-occurring-in-a-loggerhead-sea-turtle-caretta-caretta-during-mechanical-ventilation-under-general-anaesthesia
#12
LETTER
Paolo Monticelli, Joanna Hedley, Rui Pinelas
No abstract text is available yet for this article.
March 22, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28728944/ultrasound-guided-thoracic-paravertebral-block-cadaveric-study-in-foxes-vulpes-vulpes
#13
Paolo Monticelli, Ian Jones, Jaime Viscasillas
OBJECTIVE: To describe an ultrasound-guided thoracic paravertebral block in canidae. STUDY DESIGN: Prospective, experimental, cadaveric study. ANIMALS: Twelve thawed fox cadavers. METHODS: A 15 MHz linear transducer was used to visualize the paravertebral space at the level of the fifth thoracic vertebrae. Iohexol (300 mg mL(-1)) at 0.2 mL kg(-1) was injected into the right and left paravertebral spaces under ultrasound guidance using a Tuohy needle...
March 22, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28599890/the-epibox-a-simple-tool-to-train-epidural-injection-technique-in-small-animals
#14
LETTER
Yves Moens, Hendrik Lehmann
No abstract text is available yet for this article.
March 22, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28716685/the-use-of-alfaxalone-for-premedication-induction-and-maintenance-of-anaesthesia-in-pigs-a-pilot-study
#15
Sarah E Bigby, Jennifer E Carter, Sébastien Bauquier, Thierry Beths
OBJECTIVE: The evaluation of alfaxalone as a premedication agent and intravenous anaesthetic in pigs. STUDY DESIGN: Prospective, clinical trial. ANIMALS: Nine healthy, 6-8-week-old female Landrace pigs weighing 22.2 ± 1.0 kg, undergoing epidural catheter placement. METHODS: All pigs were premedicated with 4 mg kg(-1) alfaxalone, 40 μg kg(-1) medetomidine and 0.4 mg kg(-1) butorphanol administered in the cervical musculature...
March 21, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28684240/intramuscular-injection-of-alfaxalone-in-combination-with-butorphanol-for-sedation-in-cats
#16
Julia Deutsch, Colette Jolliffe, Emma Archer, Elizabeth A Leece
OBJECTIVE: To assess quality of sedation following intramuscular (IM) injection of two doses of alfaxalone in combination with butorphanol in cats. STUDY DESIGN: Prospective, randomized, 'blinded' clinical study. ANIMALS: A total of 38 cats undergoing diagnostic imaging or noninvasive procedures. METHODS: Cats were allocated randomly to be administered butorphanol 0.2 mg kg(-1) combined with alfaxalone 2 mg kg(-1) (group AB2) or 5 mg kg(-1) (group AB5) IM...
March 6, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28655497/pharmacokinetics-of-dexmedetomidine-in-isoflurane-anesthetized-new-zealand-white-rabbits
#17
Ryan S Bailey, Linda S Barter, Bruno H Pypendop
OBJECTIVE: To characterize the pharmacokinetics of dexmedetomidine when administered as a short intravenous (IV) infusion to isoflurane-anesthetized rabbits. STUDY DESIGN: Experimental study. ANIMALS: A total of six healthy adult female New Zealand White rabbits. METHODS: Rabbits were anesthetized with isoflurane in oxygen. Following determination of isoflurane minimum alveolar concentration (MAC), the anesthetic dose was reduced to 0...
March 6, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28549943/do-heat-and-moisture-exchangers-in-the-anaesthesia-breathing-circuit-preserve-body-temperature-in-dogs-undergoing-anaesthesia-for-magnetic-resonance-imaging
#18
Latifa Khenissi, Gwen Covey-Crump, Toby G Knowles, Joanna Murrell
OBJECTIVE: To investigate whether the use of a heat and moisture exchanger (HME) preserves body temperature in dogs weighing <10 kg anaesthetised for magnetic resonance imaging (MRI). STUDY DESIGN: Prospective, randomised, clinical trial. ANIMALS: Thirty-one client-owned dogs. METHODS: Dogs were assigned randomly to a treatment group [HME (n = 16) or no HME (n = 15)]. Dogs were pseudorandomised according to the premedication they were administered, either dexmedetomidine or no dexmedetomidine...
March 6, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28501489/hydroxyethyl-starch-130-0-4-compared-with-0-9-nacl-administered-to-greyhounds-with-haemorrhagic-shock
#19
Duana McBride, Anthea L Raisis, Giselle Hosgood, Lisa Smart
OBJECTIVE: To determine the cardiovascular and acid-base effects of 6% hydroxyethyl starch (HES) 130/0.4 and 0.9% sodium chloride (NaCl) administered to anaesthetized greyhounds with haemorrhagic shock. STUDY DESIGN: Prospective, experimental, complete randomized block design. ANIMALS: Twelve healthy adult greyhounds. METHODS: After 60 minutes of isoflurane anaesthesia, 48 mL kg(-1) of blood was removed to induce hypotension...
March 6, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28734855/effects-of-constant-rate-infusions-of-dexmedetomidine-or-mk-467-on-the-minimum-alveolar-concentration-of-sevoflurane-in-dogs
#20
Rachel C Hector, Marlis L Rezende, Khursheed R Mama, Eugene P Steffey, Heather K Knych, Ann M Hess, Juhana M Honkavaara, Marja R Raekallio, Outi M Vainio
OBJECTIVE: To determine the effects of low and high dose infusions of dexmedetomidine and a peripheral α2-adrenoceptor antagonist, MK-467, on sevoflurane minimum alveolar concentration (MAC) in dogs. STUDY DESIGN: Crossover experimental study. ANIMALS: Six healthy, adult Beagle dogs weighing 12.6±0.9 kg (mean±standard deviation). METHODS: Dogs were anesthetized with sevoflurane in oxygen. After a 60-minute instrumentation and equilibration period, the MAC of sevoflurane was determined in triplicate using the tail clamp technique...
March 4, 2017: Veterinary Anaesthesia and Analgesia
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