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Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi

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https://www.readbyqxmd.com/read/29731384/a-multicenter-study-on-clinical-characteristics-of-acinetobacter-bacteremia-in-patients-with-liver-cirrhosis
#1
Chang-Pan Liu, Tsung-Ta Chiang, Yuag-Meng Liu, Shu-Chen Kuo, Ya-Sung Yang, Yi-Tzu Lee, Te-Li Chen, Shou-Chuan Shih
BACKGROUND: Clinical characteristics and risk factors for mortality of Acinetobacter bacteremia in cirrhotic patients have not been investigated. METHODS: Acinetobacter bacteremia cases from four medical centers were collected from 2009 to 2014, to compare between patients with and without liver cirrhosis. Risk factors for mortality of Acinetobacter bacteremia among cirrhotic patients were identified using multivariate logistic regression. RESULTS: Among the patients with Acinetobacter bacteremia, 72 had liver cirrhosis and 816 had not...
April 25, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29555411/clinical-features-of-acute-human-immunodeficiency-virus-infection-in-taiwan-a-multicenter-study
#2
Te-Yu Lin, Chia-Jui Yang, Chung-Eng Liu, Hung-Jen Tang, Tun-Chieh Chen, Guan-Jhou Chen, Tung-Che Hung, Kuan-Yin Lin, Chien-Yu Cheng, Yi-Chien Lee, Shih-Ping Lin, Mao-Song Tsai, Yu-Lin Lee, Shu-Hsing Cheng, Chien-Ching Hung, Ning-Chi Wang
BACKGROUND/PURPOSE: Acute HIV infection is characterized by a high concentration of HIV RNA in the plasma and rapid depletion of the CD4 cell count. This multicenter, retrospective observational study aimed to characterize the manifestations of acuteHIV infection in Taiwan. METHODS: Between 1 January 2012 and 31 December 2016, all patients aged 20 years or greater who presented with acute HIV infection were included. Demographic and clinical characteristics of the patients at diagnosis were collected...
March 2, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29551298/a-novel-pathogenic-mutation-on-interleukin-7-receptor-leading-to-severe-combined-immunodeficiency-identified-with-newborn-screening-and-whole-exome-sequencing
#3
Cheng-Yu Liao, Hui-Wen Yu, Chao-Neng Cheng, Jiann-Shiuh Chen, Ching-Wei Lin, Peng-Chieh Chen, Chi-Chang Shieh
BACKGROUND: Patients with severe combined immunodeficiency (SCID), which is caused by genetic defects in immune-related genes involved in the development or activation of the adaptive immune system, often died in infancy due to severe infections before definite molecular diagnosis could be made. Although recent improvement in early diagnosis has been achieved by newborn screening, the genetic basis of many of the patients is still unknown. METHODS: Here we performed whole exome sequencing (WES) to investigate the underlying genetic causes of SCID in a proband identified with newborn screening...
March 2, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29530709/predominance-of-methicillin-resistant-staphylococcus-aureus-in-the-residents-and-environments-of-long-term-care-facilities-in-taiwan
#4
Chia-Ying Liu, Chih-Cheng Lai, Hsiu-Tzy Chiang, Min-Chi Lu, Ling-Fang Wang, Tsai-Ling Tsai, Mei-Yu Kang, Yi-Ni Jan, Yi-Ting Lo, Wen-Chien Ko, Shu-Hui Tseng, Chun-Ming Lee, Po-Ren Hsueh
BACKGROUND/PURPOSE: This study investigated the distribution and persistence of multidrug resistant organisms (MDROs) including methicillin-resistant Staphylococcus aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), carbapenem-resistant Pseudomonas aeruginosa (CRPA), and multidrug-resistant Acinetobacter baumannii (MDRAB) in six long-term care facilities (LTCFs). METHODS: We investigated the distribution of MDROs in residents of six LTCFs and their environments from January to December 2016 (intervention period)...
February 21, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29501434/utility-of-a-blood-culture-time-to-positivity-incorporated-scoring-model-in-predicting-vascular-infections-in-adults-with-nontyphoid-salmonella-bacteremia
#5
Jr-Jiun Lin, Tzu-Hua Weng, Wen-Pin Tseng, Shang-Yu Chen, Chia-Ming Fu, Hui-Wen Lin, Chun-Hsing Liao, Tai-Fen Lee, Po-Ren Hsueh, Shey-Ying Chen
BACKGROUND: Vascular infections (VI) are potentially catastrophic complications of nontyphoid Salmonella (NTS). We aimed to develop a scoring model incorporating information from blood culture time to positivity (TTP-NTSVI) and compared the prediction capability for VI among adults with NTS bacteremia between TTP-NTSVI and a previously published score (Chen-NTSVI). METHODS: This retrospective cohort study enrolled 217 adults with NTS bacteremia ≧ 50 years old...
February 21, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29500045/human-papillomavirus-infection-is-not-associated-with-laryngeal-squamous-cell-carcinoma-in-taiwan
#6
Chung-Guei Huang, Li-Ang Lee, Tuan-Jen Fang, Hsueh-Yu Li, Chun-Ta Liao, Chung-Jan Kang, Tzu-Chen Yen, Kuo-Chien Tsao, Tse-Ching Chen, Shin-Ru Shih
BACKGROUND/PURPOSE: To examine whether the prevalence rate of human papillomavirus (HPV) infection in Taiwanese patients with primary laryngeal squamous cell carcinoma (LSCC) is different from that in those with a vocal polyp (VP) or vocal fold leukoplakia (VFL). METHODS: This prospective cohort study recruited 41 consecutive patients with primary LSCC and 27 and 20 patients with VP and VFL, respectively. The HPV L1 gene in surgical specimens was detected using polymerase chain reaction...
February 21, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29500044/immunodominance-of-lipl32-93-272-peptides-revealed-by-leptospirosis-sera-and-therapeutic-monoclonal-antibodies
#7
Tippawan Pissawong, Santi Maneewatchararangsri, Nonglucksanawan Ritthisunthorn, Ngamphol Soonthornworasiri, Onrapak Reamtong, Poom Adisakwattana, Thareerat Kalambaheti, Urai Chaisri, Galayanee Doungchawee
BACKGROUND/PURPOSE: Leptospirosis is a neglected zoonosis, imposing significant human and veterinary public health burdens. In this study, recombinant LipL3293-147 and LipL32148-184 middle domain of LipL3293-184 , and LipL32171-214 , and LipL32215-272 of c-terminal LipL32171-272 truncations were defined for immunodominance of the molecule during Leptospira infections revealed by leptospirosis sera. RESULTS: IgM-dominant was directed to highly surface accessible LipL32148-184 and Lipl32171-214 ...
February 14, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29429866/breakthrough-fungemia-caused-by-rhodotorula-mucilaginosa-during-anidulafungin-therapy
#8
LETTER
Cheng-Hui Wang, Po-Ren Hsueh, Fu-Lun Chen, Wen-Sen Lee
No abstract text is available yet for this article.
February 1, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29050749/impact-of-reduced-tigecycline-susceptibility-on-clinical-outcomes-of-acinetobacter-bacteremia
#9
Yea-Yuan Chang, Yuag-Meng Liu, Chang-Pan Liu, Shu-Chen Kuo, Te-Li Chen
The higher 14-day mortality rate for patients with Acinetobacter bacteremia receiving tigecycline appropriately compared to other appropriate antibiotics (36.4% versus 14.2%, P = 0.028) was due to the poor effect of tigecycline for isolates with a minimum inhibitory concentration of 2 μg/mL (63.6% of 11 versus 14.2% of 127, P = 0.001).
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28781150/2016-guidelines-for-the-use-of-antifungal-agents-in-patients-with-invasive-fungal-diseases-in-taiwan
#10
REVIEW
Hsiang-Chi Kung, Po-Yen Huang, Wei-Ting Chen, Bor-Sheng Ko, Yee-Chun Chen, Shan-Chwen Chang, Yin-Ching Chuang
The Infectious Diseases Society of Taiwan, Medical Foundation in Memory of Dr. Deh-Lin Cheng, Foundation of Professor Wei-Chuan Hsieh for Infectious Diseases Research and Education, and CY Lee's Research Foundation for Pediatric Infectious Diseases and Vaccines have updated the guidelines for the use of antifungal agents in adult patients with invasive fungal diseases in Taiwan. This guideline replaces the 2009 version. Recommendations are provided for Candida, Cryptococcus, Aspergillus and Mucormycetes. The focus is based on up-to-date evidence on indications for treatment or prophylaxis of the most common clinical problems...
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28728904/clostridium-tetani-bacteremia-in-a-patient-with-cirrhosis-following-transarterial-chemoembolization-treatment-for-hepatocellular-carcinoma
#11
LETTER
Chih-Cheng Lai, Chi-Chung Chen, Hui-Jine Hsu, Yin-Ching Chuang, Hung-Jen Tang
No abstract text is available yet for this article.
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28711434/an-infant-with-klebsiella-oxytoca-septic-arthritis
#12
LETTER
Olof Hertting, Ola Gremark, Owe Källman, Linda Guler, Jonas Bergström
No abstract text is available yet for this article.
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28698044/resistance-to-first-and-second-line-antituberculosis-drugs-in-southern-taiwan-implications-for-empirical-treatment
#13
Cheng-Yu Kuo, Wen-Hung Wang, Chung-Hao Huang, Yen-Hsu Chen, Po-Liang Lu
BACKGROUND: Multidrug-resistant and extensively drug-resistant tuberculosis infections cause public health concerns worldwide. Local epidemiologic data about the drug resistance of Mycobacterium tuberculosis isolate (Mtb) is critical to guide appropriate empirical therapy to cure patients and restrain the spread of tuberculosis. METHODS: Antituberculosis susceptibility testing was performed for 287 Mtbs, including 63 MDR-Mtbs collected in southern Taiwan from 2011 to 2015...
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28185779/corrigendum-to-comparison-of-the-clinical-efficacy-between-tigecycline-plus-extended-infusion-imipenem-and-sulbactam-plus-imipenem-against-ventilator-associated-pneumonia-with-pneumonic-extensively-drug-resistant-acinetobacter-baumannii-bacteremia-and-correlation
#14
https://www.readbyqxmd.com/read/28065414/high-level-ambient-particulate-matter-before-influenza-attack-with-increased-incidence-of-aspergillus-antigenemia-in-southern-taiwan-2016
#15
Wen-Liang Yu, Wei-Lun Liu, Khee-Siang Chan, Chun-Chieh Yang, Che-Kim Tan, Chi-Lun Tsai, Chin-Ming Chen, Yin-Ching Chuang
We found significant correlation between the incidence of severe influenza and Aspergillus antigenemia among medical intensive care unit patients for 7-month observation (coefficient γ=0.976, p<0.001). High-level ambient pollution was noticed for 2 months before the epidemic, highlighting that influenza patients might coinfect with aspergillosis in the community.
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/27553448/effects-of-implementation-of-an-online-comprehensive-antimicrobial-stewardship-program-in-icus-a-longitudinal-study
#16
I-Ling Chen, Chen-Hsiang Lee, Li-Hsiang Su, Yu-Chin Lily Wang, Jien-Wei Liu
BACKGROUND/PURPOSE: The long-term effects of antimicrobial-stewardship programs in the intensive care units (ICUs) have not been adequately examined. We evaluated the impact of an online comprehensive antimicrobial stewardship program (OCASP) on the outcomes of patients in 200-bed medical/surgical ICUs over the course of 11 years. METHODS: We analyzed the records of adult patients admitted to ICUs during the 5 years before (n = 27,499) and the 6 years after (n = 33,834) implementation of an OCASP...
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/27422746/the-blood-lipid-regulation-of-monascus-produced-monascin-and-ankaflavin-via-the-suppression-of-low-density-lipoprotein-cholesterol-assembly-and-stimulation-of-apolipoprotein-a1-expression-in-the-liver
#17
Chun-Lin Lee, Ja-Yan Wen, Ya-Wen Hsu, Tzu-Ming Pan
BACKGROUND/PURPOSES: Monascin (MS) and ankaflavin (AK) produced by Monascus purpureus NTU 568 were proven to show excellent hypolipidemic effects in our previous studies; however, the mechanism is still unclear. METHODS: This study used MS, AK, and monacolin K as test substances and performed tests on rats fed high-fat and high-cholesterol diet for 8 weeks. The lipid levels and the related protein levels of the rats were assessed to understand the effects of MS, AK, and monacolin K on lipid metabolism...
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/27329131/incidence-and-risk-factors-of-herpes-zoster-in-human-immunodeficiency-virus-positive-patients-initiating-combination-antiretroviral-therapy-in-taiwan
#18
Yi-Chieh Lee, Chien-Ching Hung, Mao-Song Tsai, Jun-Yu Zhang, Pei-Ying Wu, Shang-Ping Yang, Yu-Zhen Luo, Hsi-Yen Chang, Wen-Chun Liu, Hsin-Yun Sun, Shan-Chwen Chang
BACKGROUND/PURPOSE: To obtain current epidemiological data for better vaccination policies, this study aimed to assess the incidence and risk factors of herpes zoster in human immunodeficiency virus (HIV)-positive patients initiating combination antiretroviral therapy (cART) in Taiwan. METHODS: Between June, 2012 and May, 2015, we prospectively identified zoster cases in HIV-positive patients initiating cART. Clinical information was collected on demographics, prior zoster, plasma HIV-1 RNA load (PVL), and CD4 count at baseline and during follow up...
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/27325144/effects-of-montelukast-on-m2-related-cytokine-and-chemokine-in-m2-macrophages
#19
Yi-Ching Lin, Ming-Yii Huang, Min-Sheng Lee, Chong-Chao Hsieh, Hsuan-Fu Kuo, Chang-Hung Kuo, Chih-Hsing Hung
BACKGROUND/PURPOSE: Asthma is a chronic airway inflammatory disease mediated by T-helper (Th)2 cells. Montelukast (trade name Singulair) is a cysteinyl leukotriene receptor antagonist used for asthma treatment. Mirroring Th1-Th2 polarization, two distinct states of macrophages have been recognized: the classically activated (M1) macrophages and the alternatively activated (M2) macrophages. M2 polarization is known to be a response to the Th2 cytokines; however, the effects of montelukast on M2 macrophages have not been well characterized...
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/27317410/regulatory-elements-of-stx2-gene-and-the-expression-level-of-shiga-like-toxin-2-in-escherichia-coli-o157-h7
#20
I Wayan Suardana, Komang Januartha Putra Pinatih, Dyah Ayu Widiasih, Wayan Tunas Artama, Widya Asmara, Budi Setiadi Daryono
BACKGROUND/PURPOSE: Shiga-like toxin (Stx) is an important factor in the pathogenesis of Escherichia coli O157:H7 infection and is responsible for some severe complications. Stx2 is usually associated with hemolytic uremic syndrome in humans. Its expression is regulated by elements located upstream of the stx2 gene, including stx2-promoter sequence, ribosome binding site, and the antiterminator q gene. The present study aimed to find the correlation between regulatory elements and the expression level of Stx2 in two local isolates of E...
February 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
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