Kubra Uslu, Firat Ozcelik, Gokmen Zararsiz, Vahap Eldem, Ahu Cephe, Izem Olcay Sahin, Recep Civan Yuksel, Hilal Sipahioglu, Zuhal Ozer Simsek, Osman Baspinar, Hilal Akalin, Yasin Simsek, Kursat Gundogan, Nuri Tutar, Aynur Karayol Akin, Yusuf Ozkul, Orhan Yildiz, Munis Dundar
The COVID-19 pandemic remains a significant public health concern despite the new vaccines and therapeutics. The clinical course of acute SARS-CoV-2 infection is highly variable and influenced by several factors related to the virus and the host. Numerous genetic studies, including candidate gene, exome, and genome sequencing studies, genome-wide association studies, and other omics efforts, have proposed various Mendelian and non-Mendelian associations with COVID-19 course. In this study, we conducted whole-exome sequencing on 90 unvaccinated patients from Turkey with no known comorbidities associated with severe COVID-19...
December 20, 2023: Genes and Immunity