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Joint, Bone, Spine: Revue du Rhumatisme

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https://www.readbyqxmd.com/read/28512007/antimalarial-drug-retinopathy%C3%A2-a-typical-%C3%A2-%C3%A2-bull-s-eyes%C3%A2-%C3%A2-appearance-of-fundus
#1
Anaïs Guiot, Mathilde Couturier, Jacques Guy Tebib, Lucie Abouaf, Fabienne Coury
No abstract.
May 13, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28512006/stress-fracture-in-athletes
#2
Jordane Saunier, Roland Chapurlat
Stress fractures are widely encountered in sport medicine and rheumatology. Stress fractures result from abnormal and repetitive loading on normal bone that lead to microdamage and then fracture. They occur after sudden increase in physical activity. They appear mostly at lower limbs. Women are at higher risk than men. Patients complain of mechanical pain. Clinical findings include focused pain and sometimes swelling. No biological test is useful for diagnosis. Plain radiographs are normal in early stage disease...
May 13, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28512005/intraosseous-venous-drainage-anomaly-at-the-tibia
#3
Thibault Rabin, Franck Grados, Bruno Bonnaire, Vincent Goëb, Patrice Fardellone
No abstract.
May 13, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28512004/contribution-of-high-resolution-peripheral-quantitative-ct-to-the-management-of-bone-and-joint-diseases
#4
Eric Lespessailles, Nada Ibrahim-Nasser, Hechmi Toumi, Roland Chapurlat
Many imaging modalities have been described to diagnose and monitor osteoporosis (OP), osteoarthritis and inflammatory rheumatic diseases. Over the last ten years, High Resolution peripheral Quantitative Computerized Tomography (HR-pQCT) was shown to be a precise and non invasive technique to study bone and joint diseases in clinical research. It allows the study of both cortical and trabecular bone microarchitecture at the distal tibia and radius, and further applications have been developed such as the study of mechanical properties by the finite element analysis...
May 13, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28499895/epstein-barr-virus-and-rheumatoid-arthritis
#5
Nathalie Balandraud, Jean Roudier
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases, with a 0.5% world-wide prevalence. The cause of RA remains unknown, however both genetic and environmental factors may contribute to its development. Among these is the Epstein-Barr Virus (EBV). Here, we discuss several aspects of the close relationship between EBV and RA. Patients with RA have impaired control of EBV infection. Indeed, they have high titres of antibodies against EBV antigens. Their peripheral blood T lymphocytes are less efficient at controlling the outgrowth of EBV-infected B cells...
May 9, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28499894/pathophysiology-of-bone-metastases-from-solid-malignancies
#6
Philippe Clézardin
Bone metastases are common complications of many cancers. Among the mechanisms that set the scene for the development of bone metastases, several are shared by all forms of metastatic dissemination (pre-metastatic niche formation and chemotactic attraction of malignant cells, which invade the host tissue) and others are specific of bone tissue (homing of malignant cells to bone marrow niches and acquisition of an osteomimetic cell phenotype). After a latency period that can last several years, the malignant cells can proliferate into tumors that alter the normal bone remodeling process by inducing dysregulation of osteoblast and osteoclast function...
May 9, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28499893/vertebroplasty-and-interventional-radiology-procedures-for-bone-metastases
#7
Jean-Denis Laredo, Jacques Chiras, Salim Kemel, Lokmane Taihi, Bassam Hamze
Advances in cancer treatments have lengthened the survival of patients with bone metastases. Optimal control of the symptoms and prevention of the complications associated with bone metastases improve quality of life. Achieving these goals increasingly involves interventional radiology procedures. These include bone consolidation and analgesic techniques such as cementoplasty (vertebroplasty at the spine); percutaneous implantation of screws, metallic reinforcement devices, or intraosseous implants; and tumor destruction using thermal methods (radiofrequency and cryotherapy), chemicals (alcohol), and drugs (chemoembolization), which have fewer indications...
May 9, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28499892/tocilizumab-for-giant-cell-arteritis-with-corticosteroid-resistant-progressive-anterior-ischemic-optic-neuropathy
#8
Julien Vionnet, Guillaume Buss, Cédric Mayer, Arseny A Sokolov, François-Xavier Borruat, François Spertini
BACKGROUND: Giant cell arteritis is an inflammatory disorder of the medium- and large-size arteries. Permanent visual loss related to arteritic anterior ischemic optic neuropathy is among the most serious complications of this disease and initial treatment usually consists in high dose corticosteroids. There is no consensus in the literature concerning the optimal therapeutic approach in giant cell arteritis patients with corticosteroid-resistant arteritic anterior ischemic optic neuropathy...
May 9, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28499891/sapho-autophagy-il-1-foxo1-and-propionibacterium-cutibacterium-acnes
#9
Jean-Marie Berthelot, Stéphane Corvec, Gilles Hayem
Overt infection by Propionibacterium acnes is lacking in many SAPHO syndromes, and antibiotics have only a transient and incomplete effect, either in SAPHO syndrome or acne. As several auto-inflammatory bone disorders sharing over-production of IL-1β can mimic SAPHO, this syndrome could partly depend on genetically encoded overproduction of IL-1β. However, cyclic intracellular infections, mostly by P. acnes, can contribute to the enhanced IL-1β release by some skin cells, and probably by bone cells. P. acnes is indeed a powerful trigger of NLRP3-inflammasome activation and IL-1β, leading to osteitis and enhanced mesenchymal cells differentiation in osteoblasts...
May 9, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28499890/interleukin-6-pathway-blockade-as-an-option-for-managing-refractory-cases-of-crystal-arthritis-two-cases-report
#10
LETTER
Neus Quilis, Mariano Andrés, Paloma Vela, Eliseo Pascual
No abstract text is available yet for this article.
May 9, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28495524/granulomatosis-with-polyangiitis-wegener-granulomatosis-a-proteinase-3-driven-disease
#11
Véronique Witko-Sarsat, Nathalie Thieblemont
Granulomatosis with polyangiitis (GPA, Wegener granulomatosis) is a systemic autoimmune vasculitis that affects small arteries, arterioles, and capillaries, most notably in the kidneys and lungs. In this disease, proteinase 3 (PR3), produced by neutrophils, is targeted by antineutrophil cytoplasmic antibodies (ANCA). Recent work by our group has shown how PR3 impairs the resolution of inflammation and deregulates the immune system. Normally, the clearance of activated neutrophils triggers an anti-inflammatory, pro-resolution process...
May 8, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28495523/hyaluronic-acid-still-useful-in-knee-osteoarthritis
#12
EDITORIAL
Pascal Richette
No abstract text is available yet for this article.
May 8, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28495522/spondyloarthritis-an-expanding-cast-of-cellular-actors
#13
EDITORIAL
Daniel Wendling, Clément Prati
No abstract text is available yet for this article.
May 8, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28495521/efficacy-of-local-glucocorticoid-after-local-anesthetic-in-bertolotti-s-syndrome-a-randomized-placebo-controlled-double-blind-trial
#14
Joëlle Glémarec, Stéphane Varin, Céline Cozic, Gilles Tanguy, Christelle Volteau, Philippe Montigny, Benoît Le Goff, Christelle Darrieutort Laffite C, Yves Maugars, Grégoire Cormier
OBJECTIVE: The primary objective of this study was to compare the efficacy of local injection of a local anesthetic with a glucocorticoid versus a local anesthetic with saline to treat low back pain due to lumbosacral transitional vertebras (LSTV) with a pseudoarticulation. METHODS: A randomized placebo-controlled double-blind study was conducted in patients with unilateral low back pain ascribed clinically to LSTV. Patients were randomized to lidocaine plus saline (LS group) or lidocaine plus cortivazol (LC group) injected locally under computed tomography guidance...
May 8, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28478208/persistent-clinical-inertia-in-gout-in-2014-an-observational-french-longitudinal-patient-database-study
#15
Milka Maravic, Natalia Hincapie, Simon Pilet, René-Marc Flipo, Frédéric Lioté
OBJECTIVE: To describe the characteristics and management of patients with gout in France during the year 2014. METHODS: Data were obtained from a computerized observational longitudinal patient database of a representative sample of 1,200 general practitioners. Patients on urate-lowering treatment and/or colchicine were described by demographics and comorbidities, quality of management indicators (serum uric acid and renal function testing), and treatment (type of urate-lowering treatment, change, and dose regimen)...
May 3, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28461199/new-structural-formats-of-therapeutic-antibodies-for-rheumatology
#16
Christophe Dumet, Jérémy Pottier, Valérie Gouilleux, Hervé Watier
Pharmaceutical companies strive continuously to develop better medications in order to remain competitive. In the arena of monoclonal antibodies and related biologics (fusion proteins containing an IgG Fc fragment), the thrust is not only toward identifying new targets, but also toward developing new molecular formats. Here, new-generation antibodies used to treat rheumatic diseases are discussed, with emphasis on relations linking structure to pharmacological effects and on the improvements expected from the new formats...
April 28, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28456601/do-we-need-animal-models%C3%A2-to-advance-research-on-inflammatory-joint-disease
#17
EDITORIAL
Marie-Christophe Boissier, Natacha Bessis
No abstract text is available yet for this article.
April 26, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28456600/beliefs-in-the-population-about-cracking-sounds-produced-during-spinal-manipulation
#18
Christophe Demoulin, Damien Baeri, Geoffrey Toussaint, Barbara Cagnie, Axel Beernaert, Jean-François Kaux, Marc Vanderthommen
OBJECTIVES: To examine beliefs about cracking sounds heard during high-velocity low-amplitude (HVLA) thrust spinal manipulation in individuals with and without personal experience of this technique. METHODS: We included 100 individuals. Among them, 60 had no history of spinal manipulation, including 40 who were asymptomatic with or without a past history of spinal pain and 20 who had nonspecific spinal pain. The remaining 40 patients had a history of spinal manipulation; among them, 20 were asymptomatic and 20 had spinal pain...
April 26, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28435082/anti-mitochondrial-antibodies-are-not-a-hallmark-of-severity-in-idiopathic-inflammatory-myopathies
#19
LETTER
Wladimir Mauhin, Kuberaka Mariampillai, Yves Allenbach, Jean-Luc Charuel, Lucile Musset, Olivier Benveniste
No abstract text is available yet for this article.
April 20, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28412476/monoclonal-gammopathy-of-undetermined-significance-and-biological-treatments-what-should-we-do
#20
EDITORIAL
Émilie Lemieux-Blanchard
No abstract text is available yet for this article.
April 12, 2017: Joint, Bone, Spine: Revue du Rhumatisme
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