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Joint, Bone, Spine: Revue du Rhumatisme

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https://www.readbyqxmd.com/read/30227223/circadian-rhythms-and-rheumatoid-arthritis
#1
Cutolo Maurizio
Circadian rhythms (Nobel prize for Medicine 2017) regulate, under action of biological clocks located both at the level of central nervous system and inside peripheral cells, several daily activities, embracing sleep, feeding times, energy metabolism, endocrine and immune functions with related pathological conditions, including rheumatoid arthritis (RA). In RA the circadian rhythms impact on cellular functions, involving night synthesis and release of proinflammatory cytokines and chemokines, cell migration to inflamed tissues, phagocytosis, proliferative cell response and all are peaking at late night...
September 15, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30201479/hip-disease-complicating-myelitis
#2
Lhuillier Marine, Cormier Grégoire, André Vincent, Varin Stéphane, Caulier Michel, Tanguy Gilles, Cozic Céline
No abstract text is available yet for this article.
September 7, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30201478/targeted-immunotherapy-strategies-in-anca-associated-vasculitis
#3
Xavier Puéchal
Targeted immunotherapy is substantially improving the management of ANCA-associated vasculitides (AAV), which include granulomatosis with polyangiitis (GPA, Wegener's granulomatosis), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA, Churg-Strauss syndrome). This article reviews the current role for targeted immunotherapy in AAV, its validated indications, and avenues for further development. Rituximab is a validated induction treatment for GPA and severe MPA. Rituximab in these indications is not less effective than cyclophosphamide and is particularly useful in patients with refractory or relapsing disease, women of childbearing potential, and patients previously treated with cyclophosphamide...
September 7, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30201477/intraarticular-synovial-osteochondromatosis-of-the-elbow-joint-with-radial-nerve-palsy
#4
Gwenaël Mevel, De Geyer, Mickaël Ropars
No abstract text is available yet for this article.
September 7, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30201476/safety-of-biological-agents-in-paediatric-rheumatic-diseases-a-real-life-multicenter-retrospective-study-using-the-jircohorte-database
#5
Natalia Cabrera, Jean-Christophe Lega, Behrouz Kassai, Carine Wouters, Anuela Kondi, Elvira Cannizzaro, Andreas Woerner, Aurelie Chausset, Samuel Roethlisberger, Cyril Jeanneret, Florence Aeschlimann, Salma Malik, Agnès Duquesne, Daniela Kaiser, Laetitia Higel, Anne Maes, Gerald Berthet, Veronique Hentgen, Isabelle Kone-Paut, Alexandre Belot, Michael Hofer
OBJECTIVE: To analyse and report the incidence of side effects of biological agents in paediatric patients with inflammatory-diseases using of real-life follow-up cohort. METHODS: In this international, observational, retrospective, multicentre study of children treated by biological agents and followed in the Juvenile Inflammatory Rheumatism (JIR) cohort (JIRcohorte) network, a Kaplan-Meier method was used to estimate the occurrence of adverse events. A Cox model was constructed to identify independent predictors of adverse events...
September 7, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30098424/sarcopenia
#6
Anne Tournadre, Gaelle Vial, Frédéric Capel, Martin Soubrier, Yves Boirie
Sarcopenia is defined as a combination of low muscle mass with low muscle function. The term was first used to designate the loss of muscle mass and performance associated with aging. Now, recognized causes of sarcopenia also include chronic disease, a physically inactive lifestyle, loss of mobility, and malnutrition. Sarcopenia should be differentiated from cachexia, which is characterized not only by low muscle mass but also by weight loss and anorexia. Sarcopenia results from complex and interdependent pathophysiological mechanisms that include aging, physical inactivity, neuromuscular compromise, resistance to postprandial anabolism, insulin resistance, lipotoxicity, endocrine factors, oxidative stress, mitochondrial dysfunction, and inflammation...
August 8, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30098423/bone-disorders-associated-with-diabetes-mellitus-and-its-treatments
#7
Bernard Cortet, Stéphanie Lucas, Isabelle Legroux-Gerot, Guillaume Penel, Christophe Chauveau, Julien Paccou
Both type 1 and type 2 diabetes mellitus are associated with bone disorders, albeit via different mechanisms. Early studies in patients with type 1 diabetes suggested a 10-fold increase in the hip fracture risk compared to nondiabetic controls. Metaanalyses published more recently indicate a somewhat smaller risk increase, with odds ratios of 6 to 7. Diminished bone mineral density is among the contributors to the increased fracture risk. Both types of diabetes are associated with decreased bone strength related to low bone turnover...
August 8, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30081200/dimethyl-fumarate-induced-migrating-polyarthralgias
#8
LETTER
Marc Villedon de Naide, Xavier Moisset, Martin Soubrier
No abstract text is available yet for this article.
August 3, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30081199/rheumatoid-arthritis-revealed-by-polyadenopathy-diarrhea-and-digestive-aa-amyloidosis
#9
LETTER
Simon Galmiche, David Buob, Soraya Fellahi, Jean-Philippe Bastard, Gilles Grateau, Sophie Georgin-Lavialle
No abstract text is available yet for this article.
August 3, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30081198/fatty-acids-and-osteoarthritis-different-types-different-effects
#10
Marieke Loef, J W Schoones, Margreet Kloppenburg, Andreea Ioan-Facsinay
While the association between obesity and osteoarthritis used to be solely regarded as a result of increased mechanical loading, systemic factors also likely play a role in the pathophysiology of osteoarthritis. Nutrient excess leading to obesity may result in lipotoxicity, which might be involved in the development of osteoarthritis. The different fatty acid types have distinct effects on inflammation. This review focusses on the currently available studies, summarizing the effects of the different fatty acid types on osteoarthritis and involved joint tissues...
August 3, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30081197/methotrexate-mechanism-in-treatment-of-rheumatoid-arthritis
#11
Benjamin Friedman, Bruce Cronstein
Methotrexate has been used in treatment of rheumatoid arthritis (RA) since the 1980s and to this day is often the first line medication for RA treatment. In this review, we examine multiple hypotheses to explain the mechanism of methotrexate efficacy in RA. These include folate antagonism, adenosine signaling, generation of reactive oxygen species (ROS), decrease in adhesion molecules, alteration of cytokine profiles, and polyamine inhibition amongst some others. Currently, adenosine signaling is probably the most widely accepted explanation for the methotrexate mechanism in RA given that methotrexate increases adenosine levels and on engagement of adenosine with its extracellular receptors an intracellular cascade is activated promoting an overall anti-inflammatory state...
August 3, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30064008/reply-to-the-comment-of-alkan-melikoglu-joint-manifestations-can-provide-diagnostic-clues-in-morquio-syndrome-a-case-report
#12
LETTER
Stéphane Mitrovic, Hélène Gouze, Thierry Schaeverbeke, Laure Gossec, Bruno Fautrel
No abstract text is available yet for this article.
July 29, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30053612/what-is-the-best-salivary-gland-ultrasonography-scoring-methods-for-the-diagnosis-of-primary-or-secondary-sj%C3%A3-gren-s-syndromes
#13
Amélie Martel, Guillaume Coiffier, Aurore Bleuzen, Jean Goasguen, Michel de Bandt, Christophe Deligny, Julie Magnant, Nicole Ferreira, Elisabeth Diot, Aleth Perdriger, François Maillot
OBJECTIVE: To evaluate the performance of salivary gland ultrasonography for the diagnosis of primary and secondary Sjögren's syndromes (pSS and sSS). METHOD: Multicenter cross-sectional study on 97 patients with clinical sicca symptoms. The pSS (n = 39) and the sSS (n = 22) met the American-European Consensus Group (AECG) classification criteria. The control patients (n = 36) with sicca symptoms did not fulfill the AECG criteria. Four scores were used to evaluate the 4 major salivary gland echostructure: the Salaffi score (0-16), Jousse-Joulin score (0-4), Hocevar score (0-48) and Milic score (0-12)...
July 24, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30053611/the-past-encounters-the-future-old-diagnostic-methods-to-check-innovative-treatments-for-carpal-tunnel-syndrome-comment-on-treatment-of-carpal-tunnel-syndrome-from-ultrasonography-to-ultrasound-surgery-by-petrover-and-richette-joint-bone-spine-2017-https-doi
#14
LETTER
Daniele Coraci, Silvia Giovannini, Claudia Loreti, Cristiano Pecchioli, Giulia Piccinini, Luca Padua
No abstract text is available yet for this article.
July 24, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30053610/reply-to-the-comment-of-fayet-et-al-obstacles-and-motivations-to-influenza-and-pneumococcal-vaccination-in-patients-with-rheumatoid-arthritis-a-qualitative-study
#15
LETTER
Manal Assala, Matthieu Groh, Philippe Blanche, Christine Vinter, Patrice Cohen, Véronique Le Guern, Xavier Puéchal, Luc Mouthon, Claire Le Jeunne, Odile Launay, Solen Kernéis
No abstract text is available yet for this article.
July 24, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30053609/incidence-of-articular-pain-and-arthritis-after-chikungunya-fever-in-the-americas-a-systematic-review-of-the-literature-and-meta-analysis
#16
Fernando Edington, Douglas Varjão, Paulo Melo
OBJECTIVE: To estimate the incidence of chronic articular symptoms after Chikungunya virus infection of patients from the American continent. METHODS: We performed a systematic review of the literature using the MEDLINE, Web of Science and Scopus databases. We included only cohort studies conducted in the American continent reporting the incidence of chronic articular symptoms after Chikungunya virus acute infection. The quality of the selected studies was evaluated through the Newcastle-Ottawa Scale for non-randomized studies and relevant data were extracted...
July 24, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30025961/the-popliteal-groove-region-a-new-target-for-the-detection-of-monosodium-urate-crystal-deposits-in-patients-with-gout-an-ultrasound-study
#17
Andrea Di Matteo, Emilio Filippucci, Edoardo Cipolletta, Matteo Ausili, Victoria Martire, Marco Di Carlo, Fausto Salaffi, Walter Grassi
OBJECTIVES: To determine the prevalence of the ultrasound findings indicating monosodium urate crystal deposits at the popliteal groove region in patients with gout; to evaluate the diagnostic accuracy of ultrasound in detecting monosodium urate crystal deposits at the popliteal groove region, patellar tendon and the knee hyaline cartilage; to investigate the correlation between the ultrasound findings at the popliteal groove region and the clinical features. METHODS: Bilateral ultrasound assessment of the popliteal groove region, patellar tendon and femoral condyles' hyaline cartilage was performed on 47 consecutive patients with gout and 37 controls...
July 17, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30025960/is-fat-that-bad-in-rheumatoid-arthritis
#18
EDITORIAL
Gaëlle Clavel, Johanna Sigaux, Luca Semerano
No abstract text is available yet for this article.
July 17, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30025959/non-pharmacologic-measures-for-gout-management-in-the-prospective-gospel-cohort-physicians-practice-and-patients-compliance-profiles
#19
Anthony Chapron, Typhaine Chopin, Maxime Esvan, Hang-Korng Ea, Frédéric Lioté, Pascal Guggenbuhl
OBJECTIVES: Gout management includes non-pharmacological measures (NPM). The main objective of this study was to describe the NPM proposed by physicians and their implementation by patients after 3-6 months. The secondary objective was to identify NPM compliance profiles among these patients. METHODS: Ancillary observational study using the GOSPEL French cohort of 1003 patients with gout, based on questionnaires for physicians and patients at inclusion and then after 3-6 months...
July 17, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30025957/serum-and-urinary-macrophage-migration-inhibitory-factor-mif-in-primary-sj%C3%A3-gren-s-syndrome
#20
LETTER
Fabien B Vincent, Tali Lang, Rangi Kandane-Rathnayake, Sarah Downie-Doyle, Eric F Morand, Maureen Rischmueller
No abstract text is available yet for this article.
July 17, 2018: Joint, Bone, Spine: Revue du Rhumatisme
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