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Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi

Akiko Kanzaki, Yoko Funasaka, Munenaga Nakamizo, Ayaka Shima, Takeshi Ryotokuji, Kazuo Dan, Mika Terasaki, Yuichi Sugisaki, Yu Fukuda, Seiji Kawana, Hidehisa Saeki
Extranodal natural killer/T-cell lymphoma (ENK/TCL) is most often in the nose or the nasopharynx but can present elsewhere. We report a rare case of ENK/TCL that presented as swelling of an upper eyelid without ocular involvement. A 76-year-old man visited our hospital with a swollen lesion of the left upper eyelid which had appeared 2 months earlier. A biopsy of the upper eyelid revealed slight perivascular and periadnexal infiltration of mononuclear cells with dermal edema. Treatment with oral prednisolone at a dosage of 20 mg/day decreased the eyelid swelling...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Yoshiaki Mizuguchi, Yasuhiro Mamada, Tetsuya Shimizu, Tomohiro Kanda, Hiroyasu Furuki, Yuichi Akama, Nobuhiko Taniai, Yoshiharu Nakamura, Masato Yoshioka, Akira Matsushita, Yoichi Kawano, Eiji Uchida
Cecal volvulus is characterized by torsion of the cecum around its own mesentery. However, cecal volvulus rarely develops soon after elective laparoscopic cholecystectomy. We report on a case of cecal volvulus that developed in a 54-year-old women 1 day after elective laparoscopic cholecystectomy and was successfully treated via colonoscopic decompression. The symptoms gradually improved in conjunction with recovery from postoperative ileus. Whether the incidence of volvulus has increased with the use of laparoscopic procedures, including laparoscopic cholecystectomy, has yet to be determined...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Takayuki Hatori, Yohei Sugiyama, Shinichiro Yamashita, Yuka Hirakubo, Kazuhito Nonaka, Ko Ichihashi
In a patient with cardiofaciocutaneous syndrome complicated by intractable infantile spasms (West syndrome), cardiac hypertrophy developed during adrenocorticotropic hormone treatment. Various types of antiepileptic drugs, intravenous immunoglobulin, thyrotropin releasing hormone, and a ketogenic diet were ineffective in this case. However, vigabatrin both decreased clinical seizures and improved electroencephalogram findings. Although vigabatrin has not been approved for use in Japan, the results in the present case suggest that this drug should be considered as an alternative therapy for cases of infantile spasms associated with syndromes involving cardiomyopathy or its potential risk factors, such as cardiofaciocutaneous syndrome...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Hiroe Onaka, Masashi Ishikawa, Yoshiaki Mizuguchi, Eiji Uchida, Atsuhiro Sakamoto
AIM: Opioids are increasingly used to control postoperative pain via intravenous patient-controlled analgesia, with several advantages. The present study evaluated the effects of intravenous patient-controlled analgesia with different doses of fentanyl on postoperative pain and on the quality of physical/emotional recovery from surgery and anesthesia. METHODS: We retrospectively reviewed data from 288 patients, and evaluated whether intravenous patient-controlled analgesia with fentanyl correlated with the degree of postoperative pain...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Hiroyuki Koami, Yuichiro Sakamoto, Ryota Sakurai, Miho Ohta, Akiko Goto, Hisashi Imahase, Mayuko Yahata, Mitsuru Umeka, Toru Miike, Futoshi Nagashima, Takashi Iwamura, Kosuke Chris Yamada, Satoshi Inoue
Recently, serum lactate level rather than systolic blood pressure (sBP) has been widely used to diagnose peripheral circulatory insufficiency, which often leads to coagulopathy with systemic inflammation. However, most of the reported disorders were examined by plasma samples. The aim of this study was to evaluate the utility of serum lactate for detecting coagulopathy with circulatory failure by using thromboelastometry as well as standard coagulation test. 192 adult patients transported to our hospital between January 2013 and September 2014 were enrolled in this retrospective study...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Masayo Aoki, Satoshi Akaishi, Junichi Nakao, Teruyuki Dohi, Hiko Hyakusoku, Rei Ogawa
BACKGROUND: Keloids are characterized by the formation of excessive scar tissue that extends beyond the area of the initial wound. Keloid redness is due to angiogenesis and chronic inflammation and is an important indicator of the severity of the lesion and the effectiveness of treatment. METHODS: The color of 33 untreated keloids from 30 patients was measured with a narrow-band reflectance colorimeter. The erythema and melanin levels in the keloids (Ek and Mk, respectively) were recorded with control data obtained from the flexor aspect of the forearm (Ec and Mc, respectively)...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Tomohiro Matsumura, Shiho Saito, Hideo Orimo
No abstract text is available yet for this article.
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Nobutoshi Hagiwara, Takeshi Matsutani, Tsutomu Nomura, Itsuo Fujita, Yoshikazu Kanazawa, Junji Ueda, Hiroki Arai, Daisuke Kakinuma, Hitoshi Kanno, Zenya Naito, Eiji Uchida
We report the first documented case of pancreatic metastasis from a gastrointestinal stromal tumor of the stomach. A 42-year-old Japanese man presented with severe abdominal discomfort. Computed tomography of the abdomen showed a huge heterogeneous mass consisting of cystic and solid components in the left upper abdomen. (18)F-Fluorodeoxyglucose positron-emission tomography revealed high tracer uptake in the abdominal mass. After total gastrectomy with lymphnodectomy was performed, a hard mass was palpated in the pancreatic tail...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Yoshio Shima, Makoto Migita
Peters' plus syndrome is a rare autosomal recessive condition characterized by a combination of typical ocular defects and other systemic abnormalities. We present a case of this uncommon syndrome that we diagnosed during a fetal ultrasonographical examination. Because the patient exhibited microcephaly and anterior staphyloma of the right eye and because impending rupture was feared, we performed ophthalmectomy during the neonatal period. Fetal ophthalmological anomalies are often detected during ultrasonographic examination targeting other systemic abnormalities, with positive family histories providing important diagnostic clues...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Ichiro Takumi, Masataka Akimoto, Akio Morita
We report on a new technical method of using an inverted and segmented galea-calvarial flap for simultaneous reconstruction of the frontal sinus and forehead. A 73-year-old man presented with the production of pus at the forehead, in which the frontal sinus had been involved 6 years postoperatively. The patient underwent surgery with our new simultaneous technique. During the 7 years of follow-up after this reconstructive surgery, no recurrence of surgical wound problems was noted.
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Masahito Koiwa, Susumu Goto, Kenji Takahashi, Toshikazu Kamada, Shinro Takai, Hiroshi Nakamura
BACKGROUND: Disease activity of rheumatoid arthritis (RA) is evaluated by composite measures, such as Disease Activity Score (DAS). Recently, much attention has been paid to a neutrophil-lymphocyte (N/L) ratio to evaluate the prognosis and the efficacy of intervention in various diseases. To determine whether the N/L ratio is a prognostic marker or a surrogate marker of response to biologics, this study investigated the N/L ratio in RA patients treated with biological agents. METHODS: The medical records were reviewed of 358 patients with RA in routine care who were treated with infliximab (144 patients), etanercept (120 patients), adalimumab (25 patients), tocilizumab (41 patients), or abatacept (28 patients)...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Hidemi Kawaji, Takuya Uematsu, Ryosuke Oba, Yoshihiko Satake, Naoya Hoshikawa, Shinro Takai
INTRODUCTION: We usually use short femoral nails for the treatment of trochanteric fracture of the femur. In this retrospective study, we investigated and compared the clinical results of the conventional intramedullary hip screw (IMHS) and the Asian IMHS, which is a redesigned version of the former. MATERIALS AND METHODS: The subjects were 42 patients; 21 treated with the Asian IMHS and 21 were treated with the conventional IMHS. From the clinical records, we retrospectively investigated the patients' age, sex, in-hospital waiting period for operation, operating time, intraoperative blood loss, walking ability before fracture and at discharge, and complication pertaining to the operation...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Youichi Kawano, Nobuhiko Taniai, Yoshiharu Nakamura, Satoshi Matsumoto, Masato Yoshioka, Akira Matsushita, Yoshiaki Mizuguchi, Tetsuya Shimizu, Hidekazu Takata, Hiroshi Yoshida, Eiji Uchida
Laparoscopic liver resection (LLR) became common in Japan when advanced techniques and instruments for the procedure became available and the national medical insurance began covering partial resection and lateral segmentectomy. A successful LLR requires a gentle and powerful hold on the specimens, a steady operating field, and fast and rapid compression of the bleeding point to achieve hemostasis. In this paper we describe two instruments developed in our department by attaching the SECUREA™ endoscopic surgical spacer to the forceps and suction tube used for LLR...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Asami Baba, Yasuhiko Kawakami, Kenichi Saito, Yoshiya L Murashima, Yasuhiko Itoh
BACKGROUND: The role of oxidative stress in susceptibility to seizures has been the focus of several recent studies. The aim of the present study was to evaluate the antiepileptic effects of the free radical scavenger edaravone on EL mice, a strain that is highly susceptible to convulsive seizures. METHODS: EL mice were treated intraperitoneally with edaravone or saline for 1 week. The levels of reduced glutathione (GSH), oxidized glutathione (GSSG) and 3 isozymes of superoxide dismutase (SOD) (cytoplasmic copper- and zinc-containing SOD, extracellular SOD, and mitochondrial manganese-containing SOD) were measured in the hippocampus, and electroencephalograms (EEGs) were used to evaluate seizure sensitivity...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
(no author information available yet)
No abstract text is available yet for this article.
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Junji Ueda, Hiroshi Yoshida, Hiroshi Makino, Hiroshi Maruyama, Tadashi Yokoyama, Atsushi Hirakata, Ichiro Akagi, Manabu Watanabe, Eiichi Uchida, Eiji Uchida
The uterus, ovary, and fallopian tube are rarely present in an inguinal hernia. We report on an operation to treat just such a rare condition for a right inguinal hernia. An 87-year-old Japanese woman was admitted with swelling in the right inguinal region and a purulent discharge from the vagina. Vital signs were stable, but the mobile mass was irreducible. Computed tomography of the abdomen indicated uterine tissue in a right inguinal hernia. We diagnosed an inguinal hernia with an incarcerated uterus and performed surgery on that basis...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Akiko Ishiwata, Kazumi Kimura
Posterior cortical atrophy (PCA) is a rare neurodegenerative disorder that has cerebral atrophy in the parietal, occipital, or occipitotemporal cortices and is characterized by visuospatial and visuoperceptual impairments. The most cases are pathologically compatible with Alzheimer's disease (AD). We describe a case of PCA in which a combination of imaging methods, in conjunction with symptoms and neurological and neuropsychological examinations, led to its being diagnosed and to AD being identified as its probable cause...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Maki Nakai, Hiroyuki Takei, Keiko Yanagihara, Koji Yamashita, Eiji Uchida
Although the use of endocrine therapy in combination with intravenous chemotherapy has not been standardized, the combination of fulvestrant and chemotherapy may be promising. A 62-year-old woman came to our hospital's outpatient clinic with extensive ascites. Approximately 10 years earlier, she had undergone mastectomy and sentinel lymph node biopsy. Pathologically invasive lobular carcinoma, with a maximum diameter of 28 mm, had been diagnosed in the left breast. The cancer had a histological grade of 2, was positive for estrogen receptor (95% or more positive cells), and was negative for both progesterone receptor (less than 1% positive cells) and human epidermal growth factor receptor 2...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Masanori Abe, Ryuji Fukazawa, Shunichi Ogawa, Makoto Watanabe, Yoshimitsu Fukushima, Tomonari Kiriyama, Hiromitsu Hayashi, Yasuhiko Itoh
BACKGROUND: The coronary arterial lesions of Kawasaki disease are mainly dilative lesions, aneurysms, and stenotic lesions formed before, after, and between aneurysms; these lesions develop in multiple branches resulting in complex coronary hemodynamics. Diagnosis of myocardial ischemia and infarction and evaluation of the culprit coronary arteries and regions is critical to evaluating the treatment and prognosis of patients. This study used hybrid imaging, in which multidetector computed tomographic (CT) images for coronary CT angiography (CCTA) and stress myocardial perfusion single-photon emission CT (SPECT) images were fused...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
Kenta Takahashi, Meiso Hayashi, Yu-Ki Iwasaki, Yasushi Miyauchi, Kenji Yodogawa, Ippei Tsuboi, Hiroshi Hayashi, Eiichiro Oka, Kanako Hagiwara, Yu-Hi Fujimoto, Wataru Shimizu
BACKGROUND: Urgent catheter ablation is often required for various tachyarrhythmias; however, its efficacy and safety in elderly patients have not been fully elucidated. METHODS: This study included consecutive octogenarians who underwent urgent radiofrequency catheter ablation (RFCA) for various serious tachyarrhythmias (urgent group, n=28) that were life-threatening, hemodynamically deleterious, or provoking ischemia, and consecutive octogenarians who underwent elective RFCA (control group, n=36)...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
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