Batia Kaplan, Rivka Goldis, Tamar Ziv, Amir Dori, Hila Magen, Amos J Simon, Alexander Volkov, Elad Maor, Michael Arad
BACKGROUND: Cardiac amyloidosis (CA) is characterized by the extracellular deposition of misfolded protein in the heart. Precise identification of the amyloid type is often challenging, but critical, since the treatment and prognosis depend on the disease form and the type of deposited amyloid. Coexistence of clinical conditions such as old age, monoclonal gammopathy, chronic inflammation, or peripheral neuropathy in a patient with cardiomyopathy creates a differential diagnosis between the major types of CA: amyloidosis light chains (AL), amyloidosis transthyretin (ATTR) and amyloidosis A (AA)...
March 2024: Israel Medical Association Journal: IMAJ