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Nordic Journal of Psychiatry

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https://www.readbyqxmd.com/read/28800269/the-connections-among-suicidal-behavior-lipid-profile-and-low-grade-inflammation-in-patients-with-major-depressive-disorder-a-specific-relationship-with-the-neutrophil-to-lymphocyte-ratio
#1
Okan Ekinci, Asli Ekinci
OBJECTIVES: The role of inflammation and lipid metabolism in the pathophysiology of suicidal behavior has received particular attention in recent years. The neutrophil-to-lymphocyte ratio (NLR) has been suggested as a new and more reliable indicator of low-grade inflammation. NLR has been found to be altered in major depressive disorder (MDD) and has been related to various factors, including chronic stress and impulsivity that were previously reported to be related to suicidal behavior...
August 11, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28750571/a-50-bp-ins-del-polymorphism-at-the-promoter-region-of-the-superoxide-dismutase-1-and-bipolar-disorder-type-1
#2
Nazanin Kordestanian, Mostafa Saadat
Bipolar disorder type 1 (BPD) is a chronic psychiatric illness and is associated with oxidative stress. Superoxide dismutase-1 (SOD1; OMIM: 147450) metabolizes highly reactive and more dangerous superoxide radicals into less reactive molecules. A functional 50-bp insertion/deletion (Ins/Del) polymorphism in the promoter region of the gene has been reported. The primary aim of the current case-control study was to explore whether the SOD1 Ins/Del polymorphism associated with the risk of BPD. A secondary aim was to investigate the association between the study polymorphism and age of onset of BPD...
July 28, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28737982/knocking-on-prison-s-door-a-10-fold-rise-in-the-number-of-psychotic-prisoners-in-finland-during-the-years-2005-2016
#3
Alo Jüriloo, Lauri Pesonen, Hannu Lauerma
BACKGROUND: As in many European countries, Finnish psychiatric services experienced a rapid process of deinstitutionalization in the 1990s. In recent decades, the decrease in numbers of psychiatric hospital beds has in several countries been found to be linked with increasing criminality among severely mentally ill individuals. It has been concluded that deinstitutionalization could be the main reason for this development. AIM: To investigate whether the prevalence of severely mentally ill persons to prison is a growing trend also in Finland...
July 24, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28737978/risk-of-violence-among-patients-in-psychiatric-treatment-results-from-a-national-census
#4
Solveig Osborg Ose, Solfrid Lilleeng, Ivar Pettersen, Torleif Ruud, Jaap van Weeghel
BACKGROUND: Adverse media coverage of isolated incidents affects the public perception of the risk of violent behavior among people with mental illness. However, the risk of violence is studied most frequently among inpatients, which falsely exaggerates the prevalence of people with mental illness because the majority of individuals receive treatment as outpatients. AIM: To estimate the prevalence of the risk of violence among inpatients and outpatients in psychiatric treatment, as well as the associations with gender, age, socio-economic status and co-morbid substance use disorders in all major diagnostic categories...
July 24, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28737958/state-and-trait-like-variation-in-morning-and-evening-components-of-morningness-eveningness-in-winter-depression
#5
Arcady A Putilov
PURPOSE: Evening preference (eveningness) can be a risk factor for depression and a shift toward morning preference (morningness) can occur in response to treatment. A study of winter depression provides possibility to longitudinally evaluate state- and trait-like variation in morningness-eveningness during treatment in winter and remission in summer. MATERIAL AND METHODS: Female patients with winter depression and controls without a psychiatric history (n = 54 and 32 with mean age ± standard deviation of 34...
July 24, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28727504/lessons-to-be-learned-from-early-psychedelic-therapy-in-denmark
#6
David Erritzoe, William A Richards
No abstract text is available yet for this article.
July 20, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28727502/triage-in-psychiatric-emergency-services-in-copenhagen-results-from-a-descriptive-1-year-evaluation-study
#7
Ditte Sæbye, Erica Bernt Høegh, Joachim Knop
Inspired by the Australasian triage system, a regional psychiatric triage system was introduced in the psychiatric emergency units (PEUs) in Copenhagen in 2011. Our aim of the study is to determine the characteristics of the patient according to the defined triage criteria and check if this is in accordance with recommendations. A random 10% data sample was obtained throughout 2012 in three PEUs of Copenhagen. Triage category, demographic, social and clinically relevant variables were collected. A total of 929 contacts were registered...
July 20, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28723254/possible-error-in-the-danish-version-of-the-who-quality-of-life-whoqol-bref-questionnaire
#8
Ane Søndergaard Thomsen, Per Bech
BACKGROUND: The WHOQOL-BREF is widely used to measure quality of life. AIMS: The goal of the present study was to use the questionnaire in a doctoral study. METHODS: We studied all the instructions provided by the WHO. RESULTS: In the Danish version of the WHOQOL-BREF there is a discrepancy between the negatively phrased question 9 and both the syntax file and the verbal instructions for coding the data provided by the WHO...
July 19, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28719249/applying-sensory-modulation-to-mental-health-inpatient-care-to-reduce-seclusion-and-restraint-a-case-control-study
#9
Charlotte Andersen, Anne Kolmos, Kjeld Andersen, Volkmar Sippel, Elsebeth Stenager
BACKGROUND: Clinical training in managing conflicts and preventing violence seldom contains sensory modulation (SM) as a method to de-escalate and prevent restraint and seclusion. Sensory-based interventions promote adaptive regulation of arousal and emotion. SM is a complementary approach that is associated with reduced rates of seclusion and restraint in mental healthcare, but there is need for more research in this area. AIMS: Using SM to reduce restraint and seclusion in inpatient mental health care...
July 18, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28696841/international-multi-site-survey-on-the-use-of-online-support-groups-in-bipolar-disorder
#10
Rita Bauer, Jörn Conell, Tasha Glenn, Martin Alda, Raffaella Ardau, Bernhard T Baune, Michael Berk, Yuly Bersudsky, Amy Bilderbeck, Alberto Bocchetta, Letizia Bossini, Angela M Paredes Castro, Eric Y W Cheung, Caterina Chillotti, Sabine Choppin, Maria Del Zompo, Rodrigo Dias, Seetal Dodd, Anne Duffy, Bruno Etain, Andrea Fagiolini, Miryam Fernández Hernandez, Julie Garnham, John Geddes, Jonas Gildebro, Ana Gonzalez-Pinto, Guy M Goodwin, Paul Grof, Hirohiko Harima, Stefanie Hassel, Chantal Henry, Diego Hidalgo-Mazzei, Vaisnvy Kapur, Girish Kunigiri, Beny Lafer, Erik R Larsen, Ute Lewitzka, Rasmus W Licht, Anne Hvenegaard Lund, Blazej Misiak, Patryk Piotrowski, Scott Monteith, Rodrigo Munoz, Takako Nakanotani, René E Nielsen, Claire O'donovan, Yasushi Okamura, Yamima Osher, Andreas Reif, Philipp Ritter, Janusz K Rybakowski, Kemal Sagduyu, Brett Sawchuk, Elon Schwartz, Ângela M Scippa, Claire Slaney, Ahmad H Sulaiman, Kirsi Suominen, Aleksandra Suwalska, Peter Tam, Yoshitaka Tatebayashi, Leonardo Tondo, Eduard Vieta, Maj Vinberg, Biju Viswanath, Julia Volkert, Mark Zetin, Peter C Whybrow, Michael Bauer
BACKGROUND: Peer support is an established component of recovery from bipolar disorder, and online support groups may offer opportunities to expand the use of peer support at the patient's convenience. Prior research in bipolar disorder has reported value from online support groups. AIMS: To understand the use of online support groups by patients with bipolar disorder as part of a larger project about information seeking. METHODS: The results are based on a one-time, paper-based anonymous survey about information seeking by patients with bipolar disorder, which was translated into 12 languages...
July 11, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28696806/measuring-personal-recovery-psychometric-properties-of-the-swedish-questionnaire-about-the-process-of-recovery-qpr-swe
#11
Elisabeth Argentzell, Jenny Hultqvist, Sandra Neil, Mona Eklund
BACKGROUND: Personal recovery, defined as an individual process towards meaning, is an important target within mental health services. Measuring recovery hence requires reliable and valid measures. The Process of Recovery Questionnaire (QPR) was developed for that purpose. AIMS: The aim was to develop a Swedish version of the QPR (QPR-Swe) and explore its psychometric properties in terms of factor structure, internal consistency, construct validity and sensitivity to change...
July 11, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28678583/lsd-treatment-in-scandinavia-emphasizing-indications-and-short-term-treatment-outcomes-of-151-patients-in-denmark
#12
Jens Knud Larsen
BACKGROUND: New research has suggested the clinical use of lysergic acid diethylamide (LSD) and psilocybin in selected patient populations. However, concerns about the clinical use of LSD were advanced in a large Danish follow-up study that assessed 151 LSD-treated psychiatric patients approximately 25 years after their treatment in the 1960s. AIMS: The purpose of the present study was to give a retrospective account of the short-term outcome of LSD treatment in these 151 Danish psychiatric patients...
July 5, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28671000/brain-derived-neurotrophic-factor-serum-and-plasma-levels-in-the-treatment-of-acute-schizophrenia-with-olanzapine-or-risperidone-6-week-prospective-study
#13
Suzan Kudlek Mikulic, Alma Mihaljevic-Peles, Marina Sagud, Maja Bajs Janovic, Lana Ganoci, Jasmina Grubisin, Martina Kuzman Rojnic, Bjanka Vuksan Cusa, Zoran Bradaš, Nada Božina
Antipsychotics have been the mainstay of the treatment of schizophrenia, and their potential role in neuroprotection could be related to brain-derived neurotrophic factor (BDNF). So far different effects on both serum and plasma levels of BDNF were reported related to the various antipsychotic treatments. Aim of this study was to investigate the influence of olanzapine or risperidone on both plasma and serum levels of BDNF in patients with acute schizophrenia. For 50 participants with acute episode of schizophrenia both plasma and serum BDNF, along with the Positive and Negative Syndrome Scale (PANSS) and the Clinical Global Impression scale, were assessed pretreatment and post treatment - after 6 weeks of either risperidone or olanzapine...
July 2, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28670953/the-probable-role-of-adrenomedullin-and-nitric-oxide-in-childhood-attention-deficit-hyperactivity-disorder
#14
Börte Gürbüz Özgür, Hatice Aksu, Mustafa Yılmaz, Sevcan Karakoç Demirkaya
BACKGROUND: The role of adrenomedullin hormone, which has been shown to be associated with many psychiatric disorders, in the etiology of ADHD and its relation to disease is not yet known. AIM: In this study, it was aimed to compare plasma adrenomedullin and nitric oxide (NO) levels of newly diagnosed, treatment-naive patients with ADHD with healthy children. METHODS: A total of 45 children with ADHD and 45 healthy children were included. The Schedule for Affective Disorders and Schizophrenia Present and Lifetime Version (K-SADS), a semi-structured interview, was applied to all cases by child and adolescent psychiatrist...
July 2, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28644753/a-comparison-of-the-neutrophil-lymphocyte-platelet-lymphocyte-and-monocyte-lymphocyte-ratios-in-schizophrenia-and-bipolar-disorder-patients-a-retrospective-file-review
#15
Selçuk Özdin, Gökhan Sarisoy, Ömer Böke
Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and monocyte-lymphocyte ratio (MLR) have recently been used as indicators of inflammation. Higher MLR and PLR values have been determined in the euthymic and manic periods in patients with bipolar disorder compared to a control group. High NLR values were determined in the only study investigating this ratio in schizophrenia patients. The purpose of this study was to compare NLR, PLR and MLR values and complete blood count elements in patients receiving treatment and hospitalized due to schizophrenic psychotic episode and bipolar disorder manic episode...
June 23, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28632431/psychometric-testing-of-a-swedish-version-of-the-apathy-evaluation-scale
#16
Maurits Johansson, Per Johansson, Erik Stomrud, Peter Hagell, Oskar Hansson
BACKGROUND: Apathy, a prevalent and clinically relevant symptom in neurodegenerative disease, is often evaluated by the instrument Apathy Evaluation Scale (AES). However, this instrument has not been translated into Swedish, halting clinical and research efforts. Furthermore, previous studies lack analyses of some basic properties, such as the legitimacy of a total score, or have analysed dimensionality by questionable methods. AIM: To translate and psychometrically evaluate a Swedish version of the AES...
June 20, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28632428/clinical-and-socio-demographic-correlates-of-anxious-distress-in-asian-outpatients-with-major-depressive-disorder
#17
Narong Maneeton, Sirijit Suttajit, Benchalak Maneeton, Surinporn Likhitsathian, Kanokkwan Eurviyanukul, Pichet Udomratn, Edwin Shih-Yen Chan, Tian-Mei Si, Ahmad Hatim Sulaiman, Chia-Hui Chen, Dianne Bautista, Manit Srisurapanont
BACKGROUND: Anxious distress in major depressive disorder (MDD) is common and associated with poor outcomes and management difficulties. AIMS: This post hoc analysis aimed to examine the socio-demographic and clinical correlates of anxiety distress in Asian outpatients with MDD. METHODS: Instead of two out of five specifiers defined by the Diagnostic and Statistical Manual Version-5, anxious distress defined in this study was operationalized as the presence of at least two out of four proxy items drawn from the 90-item Symptom Checklist, Revised (SCL-90-R)...
June 20, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28632422/risk-of-diabetes-and-dyslipidemia-during-clozapine-and-other-antipsychotic-drug-treatment-of-schizophrenia-in-iceland
#18
Oddur Ingimarsson, James H MacCabe, Magnús Haraldsson, Halldóra Jónsdóttir, Engilbert Sigurdsson
BACKGROUND: Type 2 diabetes (T2D) and raised blood lipids are associated with the use of antipsychotics, not least clozapine. AIMS: To describe the prevalence of high blood glucose levels, T2D, and dyslipidemia, in association with the use of clozapine or other antipsychotics in patients with schizophrenia in Iceland. METHOD: This study identified 188 patients treated with clozapine and 395 patients never treated with clozapine by searching the electronic health records of Landspitali, the National University Hospital...
June 20, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28598705/effectiveness-of-cognitive-behaviour-therapy-for-treatment-resistant-depression-with-psychiatric-comorbidity-comparison-of-individual-versus-group-cbt-in-an-interdisciplinary-rehabilitation-setting
#19
Pétur Hauksson, Sylvía Ingibergsdóttir, Thórunn Gunnarsdóttir, Inga Hrefna Jónsdóttir
BACKGROUND: Cognitive behaviour therapy (CBT) has been shown to be effective, yet there is a paucity of research on the differential effectiveness of individual and group CBT for adults with treatment-resistant depression with psychiatric comorbidity. AIMS: To investigate the effectiveness of individual and group CBT for inpatients, in an interdisciplinary rehabilitation setting; the extent of psychiatric comorbidity; and who benefits the most from group CBT. METHODS: All patients (n = 181) received 6 weeks of rehabilitation (treatment as usual, TAU)...
June 9, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28598701/a-double-blind-randomized-pilot-trial-comparing-computerized-cognitive-exercises-to-tetris-in-adolescents-with-attention-deficit-hyperactivity-disorder
#20
Aida Bikic, Torben Østergaard Christensen, James F Leckman, Niels Bilenberg, Søren Dalsgaard
BACKGROUND: The purpose of this trial was to examine the feasibility and efficacy of computerized cognitive exercises from Scientific Brain Training (SBT), compared to the computer game Tetris as an active placebo, in a pilot study of adolescents with attention-deficit/hyperactivity disorder (ADHD). METHOD: Eighteen adolescents with ADHD were randomized to treatment or control intervention for 7 weeks. Outcome measures were cognitive test, symptom, and motivation questionnaires...
June 9, 2017: Nordic Journal of Psychiatry
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