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Nordic Journal of Psychiatry

Stephen Fitzgerald Austin
BACKGROUND: Traditionally, treatment of psychosis has focused on the amelioration of psychopathology and return to adequate functioning: clinical recovery although there is growing recognition of the importance of subjective experiences associated with recovery: personal recovery. Positive psychiatry extends the focus of psychiatric treatment to go beyond the reduction of psychiatric symptoms and and improvement of functional disability to promote the attainment of well-being. AIM: This article examined the conceptualization of well-being from the context of treatment for psychosis, its relationship with clinical recovery and highlighted some of challenges and implications for mental health services in promoting well-being...
July 17, 2018: Nordic Journal of Psychiatry
S Kristensen, J Mainz, L Baandrup, M Bonde, P Videbech, J Holmskov, P Bech
BACKGROUND: Denmark has national clinical indicator programs for adult patients diagnosed with depression and schizophrenia, respectively. Within each program, the responsible steering group (SG) decided to add some indicators based upon patient-reported outcome measures (PROMs). AIMS: The primary aim was to describe the process of selecting PROMs and defining a national measurement concept for use in clinical practice and for indicator monitoring and the secondary aim s to collect patient recommendations for implementation...
July 17, 2018: Nordic Journal of Psychiatry
Judith Becker Nissen, Erik Parner
PURPOSE: The primary aim of the present explorative naturalistic study was to examine the association of poor insight, avoidance behavior, and not-just-right sensation with baseline parameters including obsessive-compulsive disorder (OCD) symptoms, baseline severity scores, comorbidity, and personality traits. A second aim was to examine how insight, avoidance and not-just-right sensation influence treatment outcome. MATERIALS AND METHODS: In total, 317 medical records from children and adolescents with OCD referred to a specialized OCD clinic in Denmark were recorded for baseline parameters and treatment outcome...
July 11, 2018: Nordic Journal of Psychiatry
Ayhan Bilgiç, Rukiye Çolak Sivri, İbrahim Kılınç
PURPOSE: Accumulating data demonstrate that oxidative stress may play a crucial role in obsessive-compulsive disorder (OCD). This study aimed to investigate the role of 8-F2-isoprostane, thioredoxin (Trx), and thioredoxin reductase (TrxR) in children with OCD. MATERIALS AND METHODS: Thirty-three drug-free children with OCD and 35 healthy controls were included in this study. The severity of OCD symptoms was assessed via the Children's Yale Brown Obsessive-Compulsive Scale...
June 21, 2018: Nordic Journal of Psychiatry
Seda Gulec-Yilmaz, Huseyin Gulec, Dicle Bilge Ogut, Bugra Cetin, Uzay Gormus, Turgay Isbir
AIM: In this study, we aimed to investigate possible interactions among the apolipoprotein E (ApoE) and panic disorder (PD), taking into account serum cholesterol levels and subfractions. METHODS: ApoE genotyping was performed by real-time polymerase chain reaction in DNA samples of PD patient group (n = 45) and healthy control group (n = 50). The serum lipid levels, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) subfraction analysis were examined...
June 10, 2018: Nordic Journal of Psychiatry
Hilda Kroksmark, Maj Vinberg
BACKGROUND: S100B is a calcium-binding protein located in glial cells; it is regarded as a potential biomarker in affective disorders. AIM: To review the literature investigating the role of S100B in patients with affective disorders. METHOD: A systematic review of original English language studies investigating S100B in serum, cerebrospinal fluid, plasma and lymphocytes, in patients with affective disorders, was conducted. The literature search was conducted within the PubMed database...
May 15, 2018: Nordic Journal of Psychiatry
Kirsten J Braatveit, Torbjørn Torsheim, Oddbjørn Hove
BACKGROUND: There is a reason to believe that many individuals with substance use disorder (SUD) in contact with services have an undiagnosed intellectual disability (ID). Assessing ID in persons with SUD can be challenging due to the influence of substances, time consumption, and specific requirements for the education of the assessor. On the other hand, an undiagnosed condition may lead to a lack of treatment adjustment and may result in drop-out from treatment or lack of treatment effect...
May 7, 2018: Nordic Journal of Psychiatry
Ilkka Ojansuu, Hanna Putkonen, Jari Tiihonen
PURPOSE: To analyze the causes of mortality among patients committed to compulsory forensic psychiatric hospital treatment in Finland during 1980-2009 by categorizing the causes of mortality into somatic diseases, suicides and other unnatural deaths. MATERIALS AND METHODS: The causes of mortality were analyzed among 351 patients who died during the follow-up. Standardized mortality ratio (SMR) was calculated as the ratio of observed and expected number of deaths by using the subject-years methods with 95% confidence intervals, assuming a Poisson distribution...
May 2, 2018: Nordic Journal of Psychiatry
Per Bech, Nina Timmerby
INTRODUCTION: Measurement-based care (MBC) transfers the scientific principle from controlled clinical trials to the daily routine treatment to improve the care of patients with anxiety and depression. AIM: Within the pharmacopsychometric triangle in which the domain of desired clinical effect of treatment is balanced against the domain of undesired treatment side effects in terms of the domain of restored well-being. The relevance of these domains both in the controlled clinical trials and in the MBC trials will be tested...
May 1, 2018: Nordic Journal of Psychiatry
Karolin Lindberg, Lauri Nevonen, Sanna Aila Gustafsson, Erika Nyman-Carlsson, Claes Norring
AIM: The aim of the study was to explore the psychometric properties of the Inventory of Interpersonal Problems (IIP-64) and to compare levels of interpersonal distress in Swedish female outpatients with anorexia nervosa or bulimia nervosa with age- and gender-matched controls. METHODS: Totally, 401 participants were included; anorexia nervosa (n = 74), bulimia nervosa (n = 85) and controls (n = 242). All participants completed the IIP-64. The eating disorder (ED) patients also filled out the Eating Disorder Inventory-2/3 (EDI)...
April 27, 2018: Nordic Journal of Psychiatry
Marjolein Helleman, Lars-Gunnar Lundh, Sophie I Liljedahl, Daiva Daukantaité, Sofie Westling
BACKGROUND: Brief admission (BA) is an adjunctive treatment option for individuals with self-harming behavior, having traits of borderline personality disorder (BPD). It is offered alongside outpatient psychotherapy for the purpose of strengthening autonomy, self-reflection and self-care and to increase the likelihood of being able to stay in therapy by avoiding lengthy inpatient hospitalizations. AIMS: To investigate participants' experiences with BA during the pilot phase of the Brief Admission Skåne Randomized Controlled Trial (BASRCT), in order to detect possible strengths and limitations of the intervention and gain knowledge to facilitate implementation of BA at other treatment centers...
April 27, 2018: Nordic Journal of Psychiatry
Anu Aluoja, Innar Tõru, Mait Raag, Triin Eller, Ülle Võhma, Eduard Maron
BACKGROUND: Selective serotonin re-uptake inhibitors (SSRI) have proven to be effective in treatment of depression. Still, treatment efficacy varies significantly from patient to patient and about 40% of patients do not respond to initial treatment. Personality traits have been considered one source of variability in treatment outcome. AIM: Current study aimed at identifying specific personality traits that could be predictive of treatment response and/or the dynamics of symptom change in depressive patients...
April 24, 2018: Nordic Journal of Psychiatry
Sibelnur Avcil
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder, which is multifactorial, complex, and seen most commonly in childhood. AIMS: The aim of this study was to examine the hypothesis that altered serum lipid profiles are associated with ADHD. METHODS: The study inluded 32 boys diagnosed with ADHD according to DSM-IV-R criteria and a control group of 29 healthy subjects. All patients were assessed with The Kiddie Schedule for Affective Disorders and Schizophrenia Present and Lifetime Version, the Turgay DSM-IV-based Disruptive Behavior Disorders Child and Adolescent Rating and Screening Scale, the Conners Parent Rating Scale-Revised Long Form, and the Conners Teacher Rating Scale...
April 24, 2018: Nordic Journal of Psychiatry
Anette Søgaard Nielsen, Bent Nielsen
PURPOSE: Many patients with alcohol use disorder (AUD) fail to initiate outpatient treatment after being discharged from inpatient detoxification. The aim of the present study was to investigate the effect of outreach visits (OV) on subsequent attendance in outpatient AUD treatment. METHODS: Patients admitted to a detoxification unit at a mental health hospital were randomized to either referral as usual (TAU) or OV. OV involved a nurse from the outpatient clinic meeting the patients at the hospital and advising them about outpatient treatment, presenting an 'attendance contract' and offering a first appointment...
May 2018: Nordic Journal of Psychiatry
Per Bech, Stephen Fitzgerald Austin, Marianne Engelbrecht Lau
INTRODUCTION: Patient-reported outcome measures (PROMs) for anxiety and depressive disorders are an important aspect of measurement-based care. AIM: The aim of the study was to perform a clinimetric analysis of two PROMs scales in patents with depression and anxiety. METHODS: Patients completed a 10-item version (SCL-10) of the Symptom Checklist to measure burden of symptoms and a brief 5-item version of World Health Organization Well-being scale (WHO-5) to measure quality of life...
May 2018: Nordic Journal of Psychiatry
Petter Andreas Ringen, Ann Faerden, Bjørnar Antonsen, Ragnhild S Falk, Asgeir Mamen, Eline B Rognli, Dag K Solberg, Ole A Andreassen, Egil W Martinsen
PURPOSE: Cardiovascular diseases are a major cause for the markedly reduced life expectancy in people with severe mental illness (SMI). Hospital departments should provide adequate prevention of cardiometabolic risk by optimizing prevention and treatment. Characteristics of cardiometabolic risk factors in inpatients are still not well known. We aimed to describe the status of cardiometabolic risk factors in inpatients with SMI and identify associations with psychiatric status and treatment...
May 2018: Nordic Journal of Psychiatry
Kübranur Ünal, Gamze Erzin, Rabia Nazik Yüksel, Murat Alisik, Özcan Erel
INTRODUCTION: This study aims to investigate the dynamic thiol/disulphincide homeostasis in patients with schizophrenia who have positive psychotic indications. MATERIALS AND METHODS: Forty-four patients (26 males, 18 females; mean age = 34.40 ± 8.98 years) accepted at the Department of Psychiatry of the Ankara Numune Training and Research Hospital and 33 healthy controls (15 males, 18 females; mean age of 30.30 ± 8.48 years) were included in the study...
May 2018: Nordic Journal of Psychiatry
Hayriye Baykan, Onur Durmaz, Ozgur Baykan, Merve Sahin Can, Hayrettin Kara, Adnan Adil Hismiogullari, Tunay Karlidere
PURPOSE: Neuropeptide-S (NPS) is a novel 20-amino acid peptide, mainly expressed in the central nervous system and endocrine tissues. NPS has been linked to anxiety and fear-related behaviors. The association of NPS with depression in a human population has not been previously examined. The aim of the current study was to explore the potential association of NPS with clinical depression and comorbid anxiety. MATERIALS AND METHODS: Seventy-nine patients diagnosed with major depressive disorder and seventy-eight controls were included in the study...
May 2018: Nordic Journal of Psychiatry
Berit Hjelde Hansen, Beate Oerbeck, Benedicte Skirbekk, Beáta Éva Petrovski, Hanne Kristensen
BACKGROUND: Accurate prevalence rates of the neurodevelopmental disorders (ND) and comorbid conditions in child and adolescent mental health services (CAMHS) are essential for treatment planning and organization of health care. However, valid and reliable prevalence estimates from Nordic CAMHS populations are scarce, and the published findings vary. AIMS: To report prevalence rates of ND (attention-deficit hyperactivity disorder: ADHD, tic disorder: TD or autism spectrum disorder: ASD) and comorbid disorders by a validated diagnostic instrument in children referred to CAMHS outpatient clinics...
May 2018: Nordic Journal of Psychiatry
Jiwan Gurung, Dependra Chamlagai, Nirmal Kumar Bera, Tapas Kumar Chaudhuri, Bisu Singh
PURPOSE: Chronic, low-grade inflammation is a proposed etiological factor associated with schizophrenia. Thus, various studies have been conducted to understand the role of inflammatory process in schizophrenia by using inflammatory maker C-reactive protein (CRP) with conflicting findings. Inadvertently, studies of CRP among the Indian schizophrenia patients are very few. Therefore, the present study was undertaken to investigate the role of inflammatory process among Indian Bengalee schizophrenia patients of Siliguri, using the marker CRP and its stimulating cytokine interleukin-6 (IL-6)...
May 2018: Nordic Journal of Psychiatry
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