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Progress in Transplantation

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https://www.readbyqxmd.com/read/27913799/involvement-of-recipient-transplant-coordinators-in-transplant-outpatient-clinics-in-japan-current-status-and-transplant-physician-s-thoughts-on-follow-up-clinics
#1
Kuniko Hagiwara, Natsuko Seto, Yasuko Shimizu, Shiro Takahara
CONTEXT: Transplant recipients require long-term immunosuppressive therapy, so continued medical follow-up is necessary for long-term survival. OBJECTIVE: To investigate the current role of recipient transplant coordinators (RTCs) in the outpatient care of organ transplant recipients in Japan. METHODS: We sent a questionnaire survey to doctors in transplant facilities affiliated with the Japan Society for Transplantation probing attitudes on the role of RTCs in outpatient clinics...
December 2, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27903767/characterization-of-body-composition-and-fat-mass-distribution-1-year-after-kidney-transplantation
#2
Catherine Pantik, Young-Eun Cho, Donna Hathaway, Elizabeth Tolley, Ann Cashion
PURPOSE: In some recipients, significant weight gain occurs after kidney transplantation. Weight gain is associated with poor outcomes, particularly increased cardiovascular risk. In this study, we characterized changes in body mass index and body fat mass and compared them based on gender and race. METHODS: Fifty-two kidney transplant recipients (aged ≥18 years old, 50% men, 58% African American) were enrolled into a prospective study. Body mass index and body fat mass were measured at baseline and 12 months posttransplant...
November 30, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27899718/postoperative-delirium-after-liver-transplantation-is-associated-with-increased-length-of-stay-and-lower-survival-in-a-prospective-cohort
#3
Sonja Beckmann, Maria Schubert, Hanna Burkhalter, Philipp Dutkowski, Sabina De Geest
INTRODUCTION: Although postoperative delirium (POD) is a common in-hospital complication associated with negative outcomes, evidence in liver transplantation (LT) is scarce. OBJECTIVE: We examined the incidence and duration of POD, its impact on outcomes and health-care utilization, and described predisposing and precipitating factors favoring POD development. DESIGN: This prospective cohort study included adults undergoing transplantation in a tertiary hospital...
November 28, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27895103/impact-of-donor-recipient-gender-and-race-mismatch-on-graft-outcomes-in-patients-with-end-stage-liver-disease-undergoing-liver-transplantation
#4
Yefei Zhang
CONTEXT: The discrepancy between donor supply and organ demand increased the possibility of gender and race mismatch between the donors and recipients. However, the findings of their impact on graft and patient survival are outdated and mixed. OBJECTIVE: To estimate the effects of gender and race mismatch on graft survival and patient survival among adult patients (18 years and older) with end-stage liver disease. DESIGN: A total of 38 768 patients undergoing liver transplant between 2002 and 2011 were identified from United Network for Organ Sharing database...
November 28, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27888279/predictors-of-liver-transplant-patient-survival-a-critical-review-using-a-holistic-framework
#5
Lisiane Pruinelli, Karen A Monsen, Cynthia R Gross, David M Radosevich, György J Simon, Bonnie L Westra
OBJECTIVE: Liver transplantation is a costly and risky procedure, representing 25 050 procedures worldwide in 2013, with 6729 procedures performed in the United States in 2014. Considering the scarcity of organs and uncertainty regarding prognosis, limited studies address the variety of risk factors before transplantation that might contribute to predicting patient's survival and therefore developing better models that address a holistic view of transplant patients. This critical review aimed to identify predictors of liver transplant patient survival included in large-scale studies and assess the gap in risk factors from a holistic approach using the Wellbeing Model and the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement...
November 25, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27888278/missing-domains-of-lung-transplant-patient-selection
#6
Nancy P Blumenthal, Michael G Petty, Ruth McCorkle
: The goal of consistent, predictable, and improved outcomes has continued to elude the scientific community in the 30 years since lung transplantation became the procedure of choice for patients with terminal, nonmalignant lung disease. BACKGROUND: Although there is consensus regarding disease-specific indications for lung transplant, ambiguity remains regarding how patient-specific attributes should influence lung transplant candidacy. This study had 3 aims (1) to establish the missing domains of the interdisciplinary assessment of the lung transplant candidate, (2) to have these domains validated by an international panel of lung transplant experts, and (3) to recommend the next step for inclusion of these domains into the lung transplant candidate selection process...
November 25, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27888277/looking-the-world-in-the-face-the-benefits-and-challenges-of-facial-transplantation-for-blind-patients
#7
Katrina A Bramstedt, Jan A Plock
Total bilateral blindness in the setting of facial transplantation is a controversial matter. Some transplant teams exclude these candidates, while others accept them onto their facial transplant waiting list. Using 3 cases, the clinical and ethical complexity of total bilateral blindness is explored. Guidance (medical, psychological, and social) for total bilateral blindness as both an inclusion and exclusion criterion is provided, with the stipulation that total bilateral blindness should not be an automatic exclusion criterion for facial transplantation...
November 25, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27888276/communicating-about-choices-in-transplantation-coach-results-of-a-pilot-test-using-matched-controls
#8
Heather M Traino, Stacy M West, Camilla W Nonterah, Jennifer Russell, Eva Yuen
INTRODUCTION: Previous research highlights the difficulties patients with end-stage renal disease awaiting kidney transplant experience while attempting to manage both the logistical and the content-related aspects of discussions about transplantation. This article presents pilot results of the behavioral communication intervention program, Communicating about Choices in Transplantation (COACH), designed to improve transplant candidates' communication about transplantation. RESEARCH QUESTIONS: As compared to matched controls, increases in knowledge of deceased and living donor transplantation, communication self-efficacy, intentions to hold conversations about transplantation, and self-reported discussion were expected for pilot participants from pre- and postassessment; decreases in conversational difficulties were also posited...
November 25, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27885144/treatment-of-multiple-myeloma-in-a-heart-transplant-recipient-focus-on-the-immunomodulatory-effects-of-lenalidomide
#9
Lola Xie, Bartosz Jozwik, Phillip Weeks, L Maximilian Buja, Robert Brown, Sriram Nathan, Keshava Rajagopal, Christina Paruthi, Biswajit Kar, Pranav Loyalka, Indranee Rajapreyar
Malignancy following solid organ transplant remains a significant threat to the survival of cardiac transplant recipients. Plasma cell dyscrasias including multiple myeloma have been encountered in this population, and medication treatments traditionally used to treat these disorders demonstrate immunomodulatory effects that may have implications on the transplanted allograft. Lenalidomide is an immunomodulatory agent that has been used to treat plasma cell disorders, including light-chain amyloidosis (AL) and multiple myeloma, and represents such a class of medications in which the risks and benefits in the solid organ transplant population remain to be fully elucidated...
November 24, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27885143/intrapulmonary-percussive-ventilation-as-a-lung-recruitment-strategy-in-brain-dead-organ-donors
#10
Geralyn Lerg, Linda Shanta
OBJECTIVE: To determine the strength of the evidence evaluating the effectiveness of intrapulmonary percussive ventilation (IPV) as a safe alternative or adjunctive therapy to traditional chest physiotherapy (CPT) among potential organ donors. DATA SOURCES: Literature search conducted from February 2015 to November 2015 using PubMed, Cumulative Index of Nursing and Allied Health Literature, Scopus, and bibliographies of pertinent articles. SEARCH TERMS: Intrapulmonary percussive ventilation, chest physiotherapy, chest wall oscillation, organ donors, and ventilation...
November 24, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27881814/chronic-norovirus-infections-in-cardiac-transplant-patients-considerations-for-evaluation-and-management
#11
Paul T Jurgens, Larry A Allen, Amrut V Ambardekar, Colleen K McIlvennan
Norovirus is a common self-limiting gastrointestinal infection, but in transplant recipients, symptoms can last for months and result in serious health complications. As there is currently no established treatment for chronic norovirus infection in transplant patients, management has been directed at symptom control, trial of various antivirals, and ultimately reductions in immunosuppression. We present 3 cases of chronic norovirus infection in cardiac transplant patients to illustrate various approaches to diagnosis, the prolonged nature of disease symptoms, and treatment options...
November 23, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27881813/perspectives-of-us-and-australian-hand-therapists-about-pediatric-hand-transplantation
#12
Nitin Mukesh, Katrina A Bramstedt
INTRODUCTION: Pediatric hand transplantation (PHT), an investigational therapy, was recently performed in the United States. RESEARCH QUESTIONS: Perspectives of hand therapists about PHT patient selection (inclusion and exclusion criteria), team configuration, patient assent, and patient compliance were explored. DESIGN: Quantitative survey. We used a research ethics committee-approved 18-question e-link anonymous questionnaire to survey members of the American Society of Hand Therapists and the Australian (AU) Hand Therapy Association for their perspectives on PHT...
November 23, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27758951/the-journal-broadens-publishing-opportunities-for-authors
#13
Rebecca P Winsett
No abstract text is available yet for this article.
October 6, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27683424/risk-factors-for-graft-loss-in-pediatric-renal-transplant-recipients-after-transfer-of-care
#14
Bethany Coyne, Patricia J Hollen, Guofen Yan, Kenneth Brayman
BACKGROUND: Improvements in transplantation have increased the survival of children after kidney transplantation. These patients have complex needs, and the current medical system is not prepared to effectively transfer the care of these individuals from pediatric to adult health-care systems. Too often, transfer occurs during moments of crisis and is associated with poor outcomes. OBJECTIVE: The aim of this study was to use a national database, the Scientific Registry of Transplant Recipients, to test the hypothesis that the increased risk of graft loss after transfer of care (from pediatric to adult services) for young adult kidney transplant recipients over a 2- to 3-year posttransfer follow-up period was related to these posttransfer risk factors (medication noncompliance, acute rejection, insurance status)...
September 28, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27650918/a-comparison-of-histamine-receptor-antagonists-versus-proton-pump-inhibitor-gastrointestinal-ulcer-prophylaxis-in-kidney-transplant-recipients
#15
Ginger E Rouse, Karen Hardinger, Demetra Tsapepas, Eric M Tichy
INTRODUCTION: There are several different agents that can be used for gastrointestinal (GI) ulcer prophylaxis in posttransplant recipients, such as histamine-2 receptor antagonists (H2RA) or proton pump inhibitors (PPIs). RESEARCH QUESTION: This study was conducted to compare the incidence of adverse kidney events in transplant recipients who received prophylaxis with H2RAs or PPIs. DESIGN: This retrospective study included all kidney transplant recipients from 3 transplant centers who were transplanted in 2009 through 2011...
September 20, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27633751/interviews-with-patients-who-traveled-from-macedonia-kosovo-the-netherlands-and-sweden-for-paid-kidney-transplantations
#16
L J van Balen, Frederike Ambagtsheer, N Ivanovski, W Weimar
BACKGROUND: Patients travel worldwide for paid kidney transplants. Although transplantations abroad are not always illegal, they are commonly perceived to be illegal and unethical involving risks. AIM: We aimed to describe the motivations and experiences of patients who traveled abroad for paid kidney transplantations and to examine how these transplantations were facilitated. METHODS: We interviewed 22 patients who traveled from Macedonia/Kosovo, the Netherlands, and Sweden for paid kidney transplantations between years 2000 and 2009...
September 15, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27628498/impact-of-a-clinical-solid-organ-transplant-pharmacist-on-tacrolimus-nephrotoxicity-therapeutic-drug-monitoring-and-institutional-revenue-generation-in-adult-kidney-transplant-recipients
#17
Shawn P Griffin, Joelle E Nelson
CONTEXT: Tacrolimus requires close therapeutic drug monitoring (TDM) to ensure efficacy and minimize adverse effects. Pharmacists are uniquely positioned on transplant teams to interpret levels and recommend therapy modifications. Their impact in the immediate postoperative setting has not been described previously. OBJECTIVE: To evaluate the impact of a clinical solid organ transplant pharmacist on nephrotoxicity, TDM, and revenue generation in adult kidney transplant recipients on tacrolimus...
September 14, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27619550/ethnic-racial-religious-and-demographic-predictors-of-organ-donor-registration-status-among-young-adults-in-the-southwestern-united-states
#18
Tamar Ginossar, Julian Benavidez, Zachary D Gillooly, Aarti Kanwal Attreya, Hieu Nguyen, Joshua Bentley
CONTEXT AND SETTING: New Mexico (NM) is a minority-majority state. Despite its unique cultural characteristics and documented ethnic/racial disparities in deceased organ donation (DOD), past studies did not explore predictors of organ donor registration status (ODRS) in this state. OBJECTIVES: This study aimed at identifying demographic, cultural, and religious predictors of ODRS among a diverse sample of young adults in NM. DESIGN: This study focused on recruitment of American Indian, Hispanic, and Asian American participants through online social network sites and university listservs...
September 12, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27619549/renal-transplantation-and-outcome-does-time-of-surgery-matter
#19
Roberto Manfredini, Massimo Gallerani, Alfredo De Giorgi, Ruana Tiseo, Nicola Lamberti, Fabio Manfredini, Silvia Forcellini, Alda Storari, Gaetano La Manna, Fabio Fabbian
Emergency surgery represents an independent risk factor for death and postoperative complications. The aim of this study was to investigate the literature data regarding outcome of daytime or nighttime renal transplantation surgery. Relevant papers, focused on renal transplantation surgery, time of the day, and complications, were searched across the PubMed database. We used the following search terms: "renal", "transplantation", "surgery", "daytime", "nighttime", and "outcome". A total of five papers, including 6,991 adult patients were evaluated...
September 12, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27872411/osteoporosis-in-pediatric-liver-transplantation
#20
Walid Faraj, Ghina El Nounou, Abdallah Abou Al Naaj, Nancy Nakhoul, Ali Haydar, Mohammad Khalife
Liver transplantation provides an important, often life-saving treatment for end-stage liver disease. Osteoporosis post-liver transplantation has been described in adults; however, this has not been described in the pediatric population to date. We present a case of a 13-year-old female patient who underwent an orthotopic liver transplant for cryptogenic liver cirrhosis. Her immunosuppressants were tacrolimus and prednisone. Four months posttransplant, she started complaining of bilateral lower limb pain and limping while walking, progressing to a point where she was almost immobile...
December 2016: Progress in Transplantation
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