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Progress in Transplantation

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https://www.readbyqxmd.com/read/29623761/every-day-is-a-new-day-legislative-strides-for-organ-donation-and-transplantation-continue-in-washington-dc
#1
Wade Delk
No abstract text is available yet for this article.
March 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29592635/how-inaccurate-metrics-hide-the-true-potential-for-organ-donation-in-the-united-states
#2
Laura A Siminoff, Heather M Gardiner, Maureen Wilson-Genderson, Teresa J Shafer
BACKGROUND: There is a discrepancy between the reported increase in donor conversion rates and the number of organs available for transplant. METHODS: Secondary analysis of data obtained from the Scientific Registry of Transplant Recipients from January 2003 through December 2015 was performed. The primary outcomes were the (1) number of brain-dead donors from whom solid organs were recovered and (2) number of the organs transplanted. Descriptive statistics and growth plots were used to examine the trajectory of organ donation, recovery, and transplantation outcomes over the 11-year period...
March 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29592634/risk-factors-associated-with-peripheral-neuropathy-in-heart-failure-patients-candidates-for-transplantation
#3
Chiara Minà, Sergio Bagnato, Antonino Sant'Angelo, Calogero Falletta, Gabriele Di Gesaro, Valentina Agnese, Fabio Tuzzolino, Giuseppe Galardi, Francesco Clemenza
INTRODUCTION: Peripheral neuropathy can affect patients with heart failure, though its prevalence is unknown. After heart transplantation, it can influence the postoperative course and quality of life, but screening for neuromuscular disease is not routinely performed. OBJECTIVE: The aim of this study was to identify the factors associated with neuropathy in a population of patients with heart failure who are candidates for heart transplantation. STUDY DESIGN: Data regarding patients' clinical history, including recent hospitalizations, were collected...
March 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29357760/do-spanish-medical-students-understand-the-concept-of-brain-death
#4
Antonio Ríos, A López-Navas, A López-López, F J Gómez, J Iriarte, R Herruzo, G Blanco, F J Llorca, A Asunsolo, P Sánchez, P R Gutiérrez, A Fernández, M T de Jesús, L Martínez Alarcón, M Del Olivo, L Fuentes, J R Hernández, J Virseda, J Yelamos, J A Bondía, A M Hernández, M A Ayala, P Ramírez, P Parrilla
OBJECTIVE: To analyze the level of understanding of the brain death concept among medical students in universities in Spain. METHODS: This cross-sectional sociological, interdisciplinary, and multicenter study was performed on 9598 medical students in Spain. The sample was stratified by geographical area and academic year. A previously validated self-reported measure of brain death knowledge (questionnaire Proyecto Colaborativo Internacional Donante sobre la Donación y Transplante de Organos) was completed anonymously by students...
March 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29258377/clinical-features-of-kidney-transplant-recipients-admitted-to-the-intensive-care-unit
#5
Flávio Geraldo Rezende Freitas, Fábio Lombardi, Eduardo Souza Pacheco, Tainá Veras de Sandes-Freitas, Laila Almeida Viana, Hélio Tedesco-Silva Junior, José Osmar Medina-Pestana, Antônio Tonete Bafi, Flavia Ribeiro Machado
INTRODUCTION: There is a paucity of data regarding the complications in kidney transplant patients who may require intensive care unit (ICU) management, despite being the most common solid organ transplant worldwide. OBJECTIVE: To identify the main reasons for ICU admission and to determine the factors associated with hospital mortality in kidney transplant recipients. DESIGN: This single-center retrospective cohort study was conducted between September 2013 and June 2014, including all consecutive kidney transplant patients requiring ICU admission...
March 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29649931/self-management-in-liver-transplant-recipients-a-narrative-review
#6
Dami Ko, Rebecca J Muehrer, Lisa C Bratzke
INTRODUCTION: Although self-management is essential for liver transplant recipients, there is no review that has synthesized findings related to self-management in this population. OBJECTIVE: This narrative review aimed to synthesize the current findings and identify the gaps in knowledge about self-management in liver recipients. METHODS: A search of PubMed, CINAHL Plus, PsychINFO, ProQuest, and Web of Science was conducted using the following terms: [Self-care OR Self-management OR Health behavior] AND [Liver transplantation]...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29595082/a-case-report-of-drug-eluting-balloon-as-a-new-treatment-option-for-cardiac-allograft-vasculopathy
#7
Dario Gulin, Edvard Galic, Jozica Sikic
No abstract text is available yet for this article.
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29558879/geographic-distance-from-transplant-center-does-not-impact-pediatric-heart-transplant-outcomes
#8
Meghann McKane, Debra A Dodd, Bret A Mettler, Kari A Wujcik, Justin Godown
BACKGROUND: Many pediatric heart transplant recipients live a significant distance from their transplant center. This results in families either traveling long distances or relying on outside physicians to assume aspects of their care. Distance has been implicated to play a role in congenital heart disease outcomes, but its impact on heart transplantation has not been reported. The aim of this study was to assess the impact of distance on pediatric heart transplant outcomes. METHODS: The Scientific Registry of Transplant Recipients database was queried for all pediatric heart transplant recipients from large US children's hospitals (1987-2014)...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29558878/measuring-critical-care-providers-attitudes-about-controlled-donation-after-circulatory-death
#9
James R Rodrigue, Richard Luskin, Helen Nelson, Alexandra Glazier, Galen V Henderson, Francis L Delmonico
INTRODUCTION: Unfavorable attitudes and insufficient knowledge about donation after cardiac death among critical care providers can have important consequences for the appropriate identification of potential donors, consistent implementation of donation after cardiac death policies, and relative strength of support for this type of donation. The lack of reliable and valid assessment measures has hampered research to capture providers' attitudes. Design and Research Aims: Using stakeholder engagement and an iterative process, we developed a questionnaire to measure attitudes of donation after cardiac death in critical care providers (n = 112) and examined its psychometric properties...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29558877/incidence-and-risk-factors-for-leukopenia-in-kidney-transplant-recipients-receiving-valganciclovir-for-cytomegalovirus-prophylaxis
#10
Xinyun Liang, Olusegun Famure, Yanhong Li, S Joseph Kim
CONTEXT: Valganciclovir is used not only for cytomegalovirus prophylaxis after kidney transplantation but can also induce leukopenia, thereby making patients more susceptible to other infections. The epidemiology of leukopenia in patients on valganciclovir remains poorly understood. OBJECTIVE: To determine the incidence and risk factors for leukopenia in patients receiving valganciclovir for cytomegalovirus prophylaxis after kidney transplantation. METHODS: In this single-center, retrospective, cohort study, we included kidney recipients transplanted from January 1, 2003, to December 31, 2010, to determine the incidence and risk factors for leukopenia in patients who received valganciclovir for cytomegalovirus prophylaxis...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29558876/performance-improvement-to-decrease-readmission-rates-for-patients-with-a-left-ventricular-assist-device
#11
Jackeline Iseler, John Fox, Kelly Wierenga
BACKGROUND: The 30-day readmission rate for patients with a left ventricular assist device implantation at a large, urban, Midwest hospital system (from October 2013 to September 2014) was estimated at 32.1%. PROBLEM STATEMENT: Readmission rates were a concern at this facility. Review of the readmissions, change in practice, and home expectations of patients and families have identified an opportunity to improve the transitions of care for this left ventricular assist device (LVAD) program...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29558875/elevated-body-mass-index-is-not-a-risk-factor-for-adverse-outcomes-following-ventricular-assist-device-implantation
#12
Jonathan E Hullmann, Paul J Mather
BACKGROUND: Despite ventricular assist devices (VADs) becoming more common in heart failure (HF) treatment, it is still uncertain which patients are more prone to complications. One potential risk factor is increased body mass index (BMI), which is known to increase both all-cause mortality and mortality from ischemic heart disease; however, the role of the BMI in predicting morbidity and mortality following device implantation is unclear. METHODS: The study population for this single-institution retrospective chart review consisted of 136 patients with HF, who underwent VAD implantation between 2004 and 2015...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29558874/preoperative-recipient-parameters-allow-early-estimation-of-postoperative-outcome-and-intraoperative-transfusion-requirements-in-liver-transplantation
#13
Carsten Schumacher, Hendrik Eismann, Lion Sieg, Lars Friedrich, Dirk Scheinichen, Florian W R Vondran, Kai Johanning
CONTEXT: Liver transplantation is a complex intervention, and early anticipation of personnel and logistic requirements is of great importance. Early identification of high-risk patients could prove useful. We therefore evaluated prognostic values of recipient parameters commonly available in the early preoperative stage regarding postoperative 30- and 90-day outcomes and intraoperative transfusion requirements in liver transplantation. DESIGN, SETTING, AND PARTICIPANTS: All adult patients undergoing first liver transplantation at Hannover Medical School between January 2005 and December 2010 were included in this retrospective study...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29558873/the-impact-of-share-35-policy-on-patient-survival-in-patients-undergoing-liver-transplantation-with-gender-and-race-mismatched-donors-an-analysis-of-the-united-network-for-organ-sharing-registry
#14
Yefei Zhang, Maha R Boktour
INTRODUCTION: The United Network for Organ Sharing (UNOS) instituted the Share 35 policy in June 2013 in order to reduce death on liver transplant waitlist. The effect of this policy on patient survival among patients with gender- and race-mismatched donors has not been examined. RESEARCH QUESTION: To assess the impact of Share 35 policy on posttransplantation patient survival among patients with end-stage liver disease (ESLD) transplanted with gender- and race-mismatched donors...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29402156/donor-body-mass-index-as-a-risk-factor-for-delayed-onset-of-graft-function
#15
Juraj Miklušica, Ivana Dedinská, Blažej Palkoci, Alexander Sendrey, Mariana Lajčiaková, Martin Vojtko, Denisa Osinová, L'udovít Laca
Delayed graft function continues to pose a significant challenge to clinicians in the context of kidney transplantation. The objective of this retrospective, 5-year analysis is to identify the parameters of beating heart donors and those of recipients that affect the delayed development of graft function. The monitored group was composed of 152 beating heart donors and 179 recipients. Delayed graft function was identified in 32 (17%) patients. The predictor for development of delayed graft function was the body mass index of the donor (odds ratio: 1...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29187138/up-to-a-third-of-renal-transplant-recipients-have-deficiencies-in-cognitive-functioning
#16
Lisa Stoessel, Katharina Schieber, Sabine Jank, Sandra Reber, Franziska Grundmann, Christine Lueker, Frank Vitinius, Georgios Paslakis, Kai-Uwe Eckardt, Yesim Erim
INTRODUCTION: Kidney transplantation is beneficial in improving cognitive abilities in patients with chronic kidney disease; however, there is still uncertainty concerning which cognitive domains benefit and to what extent. AIM: In the present study, cognitive functioning of renal transplant recipients was compared to normative data. Sociodemographic and clinical parameters that were associated with low cognitive performance were identified. DESIGN: A total of 109 renal transplant recipients (63% men) participated in the study, with a mean age of 51...
December 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/29187137/evaluation-of-filgrastim-therapy-in-kidney-transplant-recipients
#17
Teresa Poon, Christina M Guerra
CONTEXT: Neutropenia is associated with a high risk of serious infections in kidney transplant recipients. There are no sufficient studies of using granulocyte colony-stimulating factors, such as filgrastim, in renal transplant recipients to establish a clear, specified role of this off-label indication. Using filgrastim in these patients may increase the risk of rejection by overstimulating the immune system. OBJECTIVE: To evaluate the use of filgrastim in adult kidney transplant recipients presenting with neutropenia...
December 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/29187136/results-of-a-patient-survey-for-assessment-services-in-renal-transplant-patients-with-a-history-of-cancer
#18
Andreas Ihrig, Imad Maatouk, Susanne Fink, Sascha Pahernik, Caner Süsal, Johannes Huber, Markus Hohenfellner, Martin Zeier, Carsten Grüllich
Patients with cancer who require a kidney transplant often face a prolonged time on the waiting list to ensure a sufficient relapse-free time. Patients and relatives were invited to the patient assessment service where they get an individualized risk assessment and a recommendation for transplantation and waiting period directly from an expert panel. We investigated in 31 patients who filled out questionnaires concerning depression, anxiety, distress, and quality of life and were interviewed for their satisfaction, experiences, and circumstances of the counseling...
December 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/29187135/a-clustered-randomized-trial-of-an-educational-intervention-during-transplant-evaluation-to-increase-knowledge-of-living-donor-kidney-transplant
#19
Francis L Weng, John D Peipert, Bart K Holland, Diane R Brown, Amy D Waterman
INTRODUCTION: Maximizing education about living donor kidney transplant (LDKT) during the in-person evaluation at the transplant center may increase the numbers of kidney patients pursuing LDKT. Research Questions and Design: To test the effectiveness of a 1-time LDKT educational intervention, we performed a cluster-randomized trial among 499 patients who presented for evaluation of kidney transplant. We compared usual care education (n = 250) versus intensive LDKT education (n = 249), which was implemented only on the evaluation day and consisted of viewing a 25-minute video of information and stories about LDKT and discussion of LDKT possibilities with an educator...
December 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/29187134/correlation-between-renal-cortical-stiffness-and-histological-determinants-by-point-shear-wave-elastography-in-patients-with-kidney-transplantation
#20
A L Croci Chiocchini, C Sportoletti, G Comai, S Brocchi, I Capelli, O Baraldi, P Bruno, F Conti, C Serra, M Meola, M Zompatori, G La Manna
INTRODUCTION: Renal allograft biopsy is the gold standard for the detection of histological lesions of chronic allograft dysfunction. The identification of a noninvasive routine test would be desirable. Elastosonography is used to assess tissue stiffness according to viscosity, and no data are available on the use of point quantification shear-wave elastography (ElastPQ) for the evaluation of renal chronic lesions. RESEARCH QUESTION: To evaluate the feasibility of ElastPQ to assess cortical allograft stiffness and to determine the correlation of clinical, biological, and pathological factors with the diagnostic accuracy of kidney stiffness values in patients with histological lesions...
December 2017: Progress in Transplantation
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