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High Altitude Medicine & Biology

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https://www.readbyqxmd.com/read/29298124/inhaled-budesonide-does-not-affect-hypoxic-pulmonary-vasoconstriction-at-4559-meter-of-altitude
#1
Marc Moritz Berger, Franziska Macholz, Peter Schmidt, Sebastian Fried, Tabea Perz, Daniel Dankl, Josef Niebauer, Peter Bärtsch, Heimo Mairbäurl, Mahdi Sareban
Berger, Marc Moritz, Franziska Macholz, Peter Schmidt, Sebastian Fried, Tabea Perz, Daniel Dankl, Josef Niebauer, Peter Bärtsch, Heimo Mairbäurl, and Mahdi Sareban. Inhaled budesonide does not affect hypoxic pulmonary vasoconstriction at 4559 m of altitude. High Alt Med Biol 00:000-000, 2017.-Oral intake of the corticosteroid dexamethasone has been shown to lower pulmonary artery pressure (PAP) and to prevent high-altitude pulmonary edema. This study tested whether inhalation of the corticosteroid budesonide attenuates PAP and right ventricular (RV) function after rapid ascent to 4559 m...
January 3, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29265914/the-physiology-of-paragliding-flight-at-moderate-and-extreme-altitudes
#2
Matt Wilkes, Martin J MacInnis, Lucy A Hawkes, Heather Massey, Clare Eglin, Michael J Tipton
Wilkes, Matt, Martin J. MacInnis, Lucy A. Hawkes, Heather Massey, Clare Eglin, and Michael J. Tipton. The physiology of paragliding flight at moderate and extreme altitudes. High Alt Med Biol 00:000-000, 2017.-Paragliding is a form of free flight, with extreme-altitude paragliding being an emerging discipline. We aimed to describe the physiological demands and the impact of environmental stressors of paragliding at moderate and extreme altitudes. We recorded oxygen consumption (VO2), heart rate (HR), respiratory frequency (fR), tidal volume (VT), oxygen saturation, accelerometry (G), and altitude in 9...
December 21, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29261343/long-term-hypoxic-tolerance-in-murine-cornea
#3
Kazuhiro Kosaku, Tomonori Harada, Toyoharu Jike, Isao Tsuboi, Shin Aizawa
Kosaku, Kazuhiro, Tomonori Harada, Toyoharu Jike, Isao Tsuboi, and Shin Aizawa. Long-term hypoxic tolerance in murine cornea. High Alt Med Biol 00:000-000, 2017. AIMS: The cornea is believed to be an exceedingly sensitive organ to decreases in atmospheric oxygen concentrations. Previous corneal studies have shown the hypoxic tolerance of the cornea during short-term and local hypoxic exposure. This study investigated the tolerance of the cornea during long-term and systemic hypoxia. METHODS AND RESULTS: Mice were bred under normobaric normoxia or hypoxia (10% oxygen concentration) conditions for 140 days...
December 20, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29211505/the-effect-of-dietary-nitrate-on-nocturnal-sleep-disordered-breathing-and-arterial-oxygen-desaturation-at-high-altitude
#4
Alexander Patrician, Harald Engan, David Lundsten, Ludger Grote, Helena Vigetun-Haughey, Erika Schagatay
Patrician, Alexander, Harald Engan, David Lundsten, Ludger Grote, Helena Vigetun-Haughey, and Erika Schagatay. The effect of dietary nitrate on nocturnal sleep-disordered breathing and arterial oxygen desaturation at high altitude. High Alt Med Biol 00:000-000, 2017.-Sleep-disordered breathing and fluctuations in arterial oxygen saturation (SaO2) are common during sleep among lowlanders ascending to high altitude. Dietary nitrate (NO3-) supplementation has been shown to lower the O2 consumption in various conditions...
December 6, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29172727/objective-versus-self-reported-sleep-quality-at-high-altitude
#5
Paul J Anderson, Christina M Wood-Wentz, Kent R Bailey, Bruce D Johnson
Anderson, Paul J., Christina M. Wood-Wentz, Kent R. Bailey, and Bruce D. Johnson. Objective versus self-reported sleep quality at high altitude. High Alt Med Biol. 16:000-000, 2017. BACKGROUND: Previous studies have found little relationship between polysomnography and a diagnosis of acute mountain sickness (AMS) using the Lake Louise Symptom Questionnaire (LLSQ). The correlation between sleep question responses on the LLSQ and polysomnography results has not been explored. We compared LLSQ sleep responses and polysomnography data from our previous study of workers rapidly transported to the South Pole...
November 27, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29161114/suicide-and-high-altitude-an-integrative-review
#6
Elaine Reno, Talia L Brown, Marian E Betz, Michael H Allen, Lilian Hoffecker, Jeremy Reitinger, Robert Roach, Benjamin Honigman
Reno, Elaine, Talia L. Brown, Marian E. Betz, Michael H. Allen, Lilian Hoffecker, Jeremy Reitinger, Robert Roach, and Benjamin Honigman. Suicide and high altitude: an integrative review. High Alt Med Biol 00:000-000, 2017. INTRODUCTION: Suicide rates are greater at high altitudes, and multiple mechanisms have been suggested for this relationship, including hypoxia, differences in population density, characteristics of suicide victims, and firearms ownership and access. To better understand these potential mechanisms, studies evaluating the associations between high altitude and suicide were examined...
November 21, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29161094/the-effect-of-resistance-training-in-a-hypoxic-chamber-on-physical-performance-in-elite-rugby-athletes
#7
Brad Mayo, Cory Miles, Stacy Sims, Matthew Driller
Mayo, Brad, Cory Miles, Stacy Sims, and Matthew Driller. The effect of resistance training in a hypoxic chamber on physical performance in elite rugby athletes. High Alt Med Biol 00:000-000, 2017.-Limited research suggests that muscle adaptations may be enhanced through resistance training in a hypoxic environment. Seventeen professional rugby union athletes (age [mean ± SD], 24 ± 3 years; body mass, 98.7 ± 12.8 kg; and height, 188.9 ± 7.9 cm), performed 12 resistance training sessions over a 3-week period...
November 21, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29131669/research-in-high-altitude-and-mountain-emergency-medicine-is-methodology-key
#8
Hermann Brugger, Matiram Pun, Erik R Swenson, Markus Falk
No abstract text is available yet for this article.
November 13, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29125907/risk-of-type-2-diabetes-mellitus-development-in-the-native-population-of-low-and-high-altitude-regions-of-kyrgyzstan-finnish-diabetes-risc-score-questionnaire-results
#9
Marina S Moldobaeva, Anastasiya V Vinogradova, Marina K Esenamanova
Moldobaeva, Marina S., Anastasiya V. Vinogradova, and Marina K. Esenamanova. Risk of type 2 diabetes mellitus development in the native population of low- and high-altitude regions of Kyrgyzstan: Finnish Diabetes Risc Score questionnaire results. High Alt Med Biol. 00:000-000, 2017. OBJECTIVE: The number of patients with diabetes is steadily growing, but likely only half of all cases are ever identified. The Kyrgyz, native inhabitants of Central Asia, live in the mountainous area and have a particular lifestyle and nutrition...
November 10, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29112466/the-effect-of-inspiratory-resistance-on-exercise-performance-and-perception-in-moderate-normobaric-hypoxia
#10
Yongsuk Seo, Jeremiah Vaughan, Tyler D Quinn, Brittany Followay, Raymond Roberge, Ellen L Glickman, Jung-Hyun Kim
Seo, Yongsuk, Jeremiah Vaughan, Tyler D. Quinn, Brittany Followay, Raymond Roberge, Ellen L. Glickman, and Jung-Hyun Kim. The effect of inspiratory resistance on exercise performance and perception in moderate normobaric hypoxia. High Alt Med Biol. 00:000-000, 2017. PURPOSE: Respirators are simple and efficient in protecting workers against toxic airborne substances; however, their use may limit the physical performance of workers. The purpose of this study was to determine the effect of inspiratory resistance on physical performance and breathing perception in normobaric hypoxia...
November 7, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29077517/therapeutic-efficacy-of-methazolamide-against-intermittent-hypoxia-induced-excessive-erythrocytosis-in-rats
#11
Zhiqing Zhang, Zhonghai Xiao, Bingnan Deng, Xiaohua Liu, Wei Liu, Hongjing Nie, Xi Li, Zhaoli Chen, Danfeng Yang, Ruifeng Duan
Zhang, Zhiqing, Zhonghai Xiao, Bingnan Deng, Xiaohua Liu, Wei Liu, Hongjing Nie, Xi Li, Zhaoli Chen, Danfeng Yang, and Ruifeng Duan. Therapeutic efficacy of methazolamide against intermittent hypoxia-induced excessive erythrocytosis in rats. High Alt Med Biol 00:000-000, 2017.-This study aimed to determine whether methazolamide is effective for the treatment of chronic mountain sickness. Forty-eight male Wistar rats were randomly divided into eight groups: normoxia control, hypoxia control, hypoxia + acetazolamide (30 mg·kg(-1)·d(-1)), and five hypoxia + methazolamide groups (5, 10, 30, 90, and 120 mg·kg(-1)·d(-1))...
October 27, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29064292/psychophysiological-response-and-fine-motor-skills-in-high-altitude-parachute-jumps
#12
Vicente Javier Clemente-Suárez, José Juan Robles-Pérez, Ketty Herrera-Mendoza, Beliña Herrera-Tapias, Jesús Fernández-Lucas
Clemente-Suárez, Vicente Javier, José Juan Robles-Pérez, Ketty Herrera-Mendoza, Beliña Herrera-Tapias, and Jesús Fernández-Lucas. Psychophysiological response and fine motor skills in high-altitude parachute jumps. High Alt Med Biol 00:000-000, 2017.-We analyzed the psychophysiological response and specific fine motor skill of an experienced jumper in HALO (high altitude low opening) and HAHO (high altitude high opening) parachute jumps. Eight HALO and eight HAHO jumpers were analyzed. They jumped at 5500 m, HALO jumpers opened the parachute at 500 m and HAHO jumpers at 4300 m of altitude...
October 24, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28945137/exercise-capacity-of-amateur-mountain-runners-and-ski-mountaineers
#13
Johannes Burtscher, Hannes Gatterer, Martin Faulhaber, Martin Burtscher
No abstract text is available yet for this article.
December 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28910201/reentry-high-altitude-pulmonary-edema-in-the-himalayas
#14
Santosh Baniya, Christopher Holden, Buddha Basnyat
Baniya, Santosh, Christopher Holden, and Buddha Basnyat. Reentry high altitude pulmonary edema in the Himalayas. High Alt Med Biol. 18:425-427, 2017.-Reentry high altitude pulmonary edema (HAPE), a subset of HAPE, is a well recognized, life-threatening illness documented almost exclusively in the North and South Americans, who live at high altitude (>2500 m) and return to their homes after a brief sojourn of days to months at lower altitude. This phenomenon has not been reported in Sherpas or other people of Tibetan origin in Nepal or India...
December 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29035594/total-body-water-dynamics-estimated-with-bioelectrical-impedance-vector-analysis-and-b-type-natriuretic-peptide-after-exposure-to-hypobaric-hypoxia-a-field-study
#15
Giacomo Strapazzon, Matiram Pun, Tomas Dal Cappello, Emily Procter, Piergiorgio Lochner, Hermann Brugger, Antonio Piccoli
Strapazzon, Giacomo, Matiram Pun, Tomas Dal Cappello, Emily Procter, Piergiorgio Lochner, Hermann Brugger, and Antonio Piccoli. Total body water dynamics estimated with bioelectrical impedance vector analysis and B-type natriuretic peptide after exposure to hypobaric hypoxia: A field study. High Alt Med Biol. 18:000-000, 2017.-The relationship between total body water (TBW) dynamics and N-terminal pro-B-type natriuretic peptide (NT-proBNP), a stable metabolite of B-type natriuretic peptide, during acute high altitude exposure is not known...
October 16, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29035586/hemoconcentration-during-maximum-exercise-in-miners-with-chronic-intermittent-exposure-to-hypobaric-hypoxia-3800%C3%A2-m
#16
Fernando A Moraga, Jorge Osorio, Rodrigo Calderón-Jofré, Andrés Pedreros
Moraga, Fernando A., Jorge Osorio, Rodrigo Calderón-Jofré, and Andrés Pedreros. Hemoconcentration during maximum exercise in miners with chronic intermittent exposure to hypobaric hypoxia (3800 m). High Alt Med Biol. 16:000-000, 2017. OBJECTIVE: To evaluate the effect of maximum exercise on hemoconcentration in miners with chronic intermittent hypobaric hypoxia (CIHH) at 3800 m. MATERIALS AND METHODS: Sixteen miners with CIHH at high altitude (3800 m) were subjected to maximum exercise levels on a cycle ergometer, increasing exercise load by 50 W every 3 minutes at sea level and high altitude (3800 m)...
October 16, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28981369/the-elusive-path-of-brain-tissue-oxygenation-and-cerebral-perfusion-in-harness-hang-syncope-in-mountain-climbers
#17
Francesca Lanfranconi, Luca Pollastri, Giovanni Corna, Manuela Bartesaghi, Massimiliano Novarina, Alessandra Ferri, Giuseppe Andrea Miserocchi
Lanfranconi, Francesca, Luca Pollastri, Giovanni Corna, Manuela Bartesaghi, Massimiliano Novarina, Alessandra Ferri, and Giuseppe Andrea Miserocchi. The elusive path of brain tissue oxygenation and cerebral perfusion in harness hang syncope in mountain climbers. High Alt Med Biol. 18:000-000, 2017. AIM: Harness hang syncope (HHS) is a risk that specifically affects wide ranges of situations requiring safety harnesses in mountains. An irreversible orthostatic stasis could lead to death if a prompt rescue is not performed...
October 5, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28968162/severe-hypothermia-management-in-mountain-rescue-a-survey-study
#18
Paweł Podsiadło, Tomasz Darocha, Sylweriusz Kosiński, Kinga Sałapa, Mirosław Ziętkiewicz, Tomasz Sanak, Rachel Turner, Hermann Brugger
Podsiadło, Paweł, Tomasz Darocha, Sylweriusz Kosiński, Kinga Sałapa, Mirosław Ziętkiewicz, Tomasz Sanak, Rachel Turner, and Hermann Brugger. Severe hypothermia management in mountain rescue: a survey study. High Alt Med Biol 00:000-000, 2017. INTRODUCTION: Severe hypothermia is a rare but demanding medical emergency. Although mortality is high, if well managed, the neurological outcome of survivors can be excellent. The aim of the study was to assess whether mountain rescue teams (MRTs) are able to meet the guidelines in the management of severe hypothermia, regarding their equipment and procedures...
October 2, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28953422/indications-and-outcomes-of-helicopter-rescue-missions-in-alpine-mountain-huts-a-retrospective-study
#19
Mathieu Pasquier, Louis Marxer, Hervé Duplain, Vincent Frochaux, Florence Selz, Pierre Métrailler, Grégoire Zen Ruffinen, Olivier Hugli
Pasquier, Mathieu, Louis Marxer, Hervé Duplain, Vincent Frochaux, Florence Selz, Pierre Métrailler, Grégoire Zen Ruffinen, and Olivier Hugli. Indications and outcomes of helicopter rescue missions in alpine mountain huts: a retrospective study. High Alt Med Biol 00:000-000, 2017. AIMS: This retrospective study describes the rescue indications and outcome of patients rescued by helicopter from mountain huts in the Swiss Alps. The hospital course and operational data were also studied...
September 27, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28949829/performance-mood-and-anxiety-during-a-climb-of-mount-everest
#20
Heikki M Karinen, Martti T Tuomisto
Karinen, Heikki M., and Martti T. Tuomisto. Performance, mood, and anxiety during a climb of Mount Everest. High Alt Med Biol. 16:000-000, 2017. BACKGROUND: Various studies have shown the deleterious effects of high-altitude hypoxia on visual, motor, somatosensory, cognitive, and emotional function and also in intelligence tests, reaction time, speech comprehension, hand steadiness, visual contrast discrimination, and word association tests. Because optimal cognitive abilities may be crucial for mountain climbers' safety, this study was intended to evaluate the changes in cognitive performance, mood, and anxiety during an Everest expedition lasting almost 3 months...
September 26, 2017: High Altitude Medicine & Biology
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