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High Altitude Medicine & Biology

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https://www.readbyqxmd.com/read/30204493/effects-of-high-intensity-interval-training-under-normobaric-hypoxia-on-cardiometabolic-risk-markers-in-overweight-obese-women
#1
Alba Camacho-Cardenosa, Marta Camacho-Cardenosa, Javier Brazo-Sayavera, Martin Burtscher, Rafael Timón, Guillermo Olcina
Camacho-Cardenosa, Alba, Marta Camacho-Cardenosa, Javier Brazo-Sayavera, Martin Burtscher, Rafael Timón, and Guillermo Olcina. Effects of high-intensity interval training under normobaric hypoxia on cardiometabolic risk markers in overweight/obese women. High Alt Med Biol. 16:000-000, 2018.-Promising benefits on cardiometabolic risk factors have been reported with prolonged programs of cyclic hypoxia. The aim of this study was to examine whether cyclic hypoxia exposure while exercising through two protocols of high-intensity interval training in overweight/obese women is more effective to improve cardiometabolic risk markers than exercising in normoxia...
September 11, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/30192653/inhibition-of-suicidal-erythrocyte-death-by-chronic-hypoxia
#2
Feng Tang, Lin Feng, Runle Li, Wei Wang, Huihui Liu, Quanyu Yang, Ri-Li Ge
Tang, Feng, Lin Feng, Runle Li, Wei Wang, Huihui Liu, Quanyu Yang, and Ri-Li Ge. Inhibition of suicidal erythrocyte death by chronic hypoxia. High Alt Med Biol. 00:000-000, 2018. BACKGROUND/AIMS: High-altitude polycythemia is defined by the increase of hematocrit and hemoglobin at high altitudes caused by production of excessive erythrocytes. Eryptosis is a process by which mature erythrocytes undergo self-destruction sharing several features with apoptosis. However, the eryptosis in high-altitude hypobaric hypoxia is unknown...
September 7, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/30183350/on-site-treatment-of-snow-avalanche-victims-from-bench-to-bedside
#3
Giacomo Strapazzon, Hermann Brugger
Strapazzon Giacomo and Hermann Brugger. On-site treatment of snow avalanche victims: From bench to bedside. High Alt Med Biol. 00:000-000, 2018.-The number of avalanche accidents involving winter recreationists has notably increased in recent decades due to the increasing popularity of outdoor winter activities. The International Liaison Committee on Cardiopulmonary Resuscitation, the International Commission for Mountain Emergency Medicine (ICAR Medcom), and the Wilderness Medical Society have recently published evidenced-based recommendations for the on-site treatment of snow avalanche victims...
September 5, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/30179522/rapidly-progressing-fatal-high-altitude-illness-in-a-patient-with-hyperthyroidism
#4
Sang Jae Noh, Ho Lee
Noh, Sang Jae and Ho Lee. Rapidly progressing fatal high-altitude illness in a patient with hyperthyroidism. High Alt Med Biol 00:000-000, 2018. High-altitude illness (HAI) refers to a broad spectrum of diseases ranging from acute mountain sickness to high-altitude cerebral and pulmonary edema that are induced by high-altitude hypoxic stress. In this study, we present a case of a rapidly progressing fatal HAI (high-altitude cerebral edema and pulmonary edema) in a patient with hyperthyroidism. The victim is a 20-year-old female being treated for Graves' disease, who died after visiting a high-altitude region for travel...
September 4, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/30153042/altitude-and-variable-effects-on-infant-mortality-in-the-united-states
#5
Robert S Levine, Jason L Salemi, Maria C Mejia de Grubb, Sarah K Wood, Lisa Gittner, Hafiz Khan, Michael A Langston, Baqar A Husaini, George Rust, Charles H Hennekens
Levine, Robert S., Jason L. Salemi, Maria C. Mejia de Grubb, Sarah K. Wood, Lisa Gittner, Hafiz Khan, Michael A. Langston, Baqar A. Husaini, George Rust, and Charles H. Hennekens. Altitude and variable effects on infant mortality in the United States. High Alt Med Biol. 00:000-000, 2018. AIMS: To explore whether altitude has different effects on infant mortality from newborn respiratory distress, nontraumatic intracranial hemorrhage, and necrotizing enterocolitis. RESULTS: Infants born in the US Mountain Census Division (AR, CO, ID, NV, NM, UT, and WY) had lower mortality from newborn respiratory distress (p < 0...
August 28, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/30153038/re-increased-cytokines-at-high-altitude-lack-of-effect-of-ibuprofen-on-acute-mountain-sickness-physiological-variables-or-cytokine-levels-by-lundeberg-et-al-high-alt-med-biol-2018-epub-ahead-of-print-doi-10-1089-ham-2017-0144
#6
https://www.readbyqxmd.com/read/30132730/infrared-thermographic-analysis-of-surface-temperature-of-the-hands-during-exposure-to-normobaric-hypoxia
#7
Daniel Jones, Samuel F Covins, Gavin E Miller, Kenneth I Morrison, Alexander G Clark, Samuel D Calcott, Alasdair M Anderson, Samuel J E Lucas, Christopher H E Imray
Jones, Daniel, Samuel F. Covins, Gavin E. Miller, Kenneth I. Morrison, Alexander G. Clark, Samuel D. Calcott, Alasdair M. Anderson, Samuel J.E. Lucas, Christopher H.E. Imray, and the Warwick Altitude Research Group. Infrared red thermographic analysis of surface temperature of the hands during exposure to normobaric hypoxia. High Alt Med Biol. 00:000-000, 2018.-Frostbite and other cold-related injuries commonly develop during prolonged exposure to the low environmental temperatures of polar and mountainous regions...
August 22, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/30118328/case-report-of-frostbite-with-delay-in-evacuation-field-use-of-iloprost-might-have-improved-the-outcome
#8
Sebastián Irarrázaval, Pablo Besa, Emmanuel Cauchy, Prativa Pandey, Jorge Vergara
Irarrázaval, Sebastián, Pablo Besa, Emmanuel Cauchy, Prativa Pandey, and Jorge Vergara. Case report of frostbite with delay in evacuation: field use of iloprost might have improved the outcome. High Alt Med Biol 00:000-000, 2018. -Frostbite is a common injury in high altitude medicine. Intravenous vasodilators have a proven efficacy and, recently, have been proposed as a safe outpatient treatment. Nevertheless, the lack of availability and consequently delayed application of this treatment option can result in poor clinical outcomes for patients...
August 17, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/30118327/comparison-of-echocardiographic-parameters-between-healthy-highlanders-in-tibet-and-lowlanders-in-beijing
#9
Ying Yang, Duo-Ji Zha-Xi, Wei Mao, Guang Zhi, Bin Feng, Yun-Dai Chen
Yang, Ying, Duo-Ji Zha-Xi, Wei Mao, Guang Zhi, Bin Feng, and Yun-Dai Chen. Comparison of echocardiographic parameters between healthy highlanders in Tibet and lowlanders in Beijing. High Alt Med Biol. 16:000-000, 2018.-The hearts of highlanders exhibit distinct features compared with the hearts of lowlanders. However, previous findings have not been verified in a large-scale Tibetan population study. The aim of this study was to present differences in echocardiography results among healthy native Tibetans, acclimatized Han highlanders, and Han lowlanders at sea level...
August 17, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/30067104/frostbite-injuries-in-the-austrian-alps-a-retrospective-11-year-national-registry-study
#10
Mathias Ströhle, Simon Rauch, Philipp Lastei, Monika Brodmann Maeder, Hermann Brugger, Peter Paal
Ströhle, Mathias, Simon Rauch, Philipp Lastei, Monika Brodmann Maeder, Hermann Brugger, and Peter Paal. Frostbite injuries in the Austrian Alps: a retrospective 11-year national registry study. High Alt Med Biol 00:000-000, 2018. OBJECTIVES: Frostbite is a cold injury mostly affecting the extremities. The objective of this study was to reveal the incidence of frostbite injuries in the Austrian Alps, to search for frostbite risk factors, and thereby optimize prevention and treatment. METHODS: Out-of-hospital data in the National Registry of Alpine Accidents from January 1, 2005, to December 31, 2015, were screened for frostbite injuries...
August 1, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/30067102/characteristics-of-headache-and-relationship-to-acute-mountain-sickness-at-4559-meters
#11
Michael Schneider, Peter Bärtsch
Schneider, Michael, and Peter Bärtsch. Characteristics of headache and relationship to acute mountain sickness at 4559 meters. High Alt Med Biol. 00:000-000, 2018.-The goals of this study were to characterize headache at high altitude in relation to the severity of acute mountain sickness (AMS), to investigate whether a history of migraine or nonmigrainous headache at low altitude is a risk factor for AMS and to estimate its effect size in relation to established major risk factors. We performed a secondary, extended analysis of data obtained from 1320 mountaineers staying overnight at the Capanna Margherita (4559 m)...
August 1, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/30010429/the-use-of-e-learning-in-medical-education-for-mountain-rescuers-concerning-hypothermia
#12
Paweł Podsiadło, Sylweriusz Kosiński, Tomasz Darocha, Kinga Sałapa, Tomasz Sanak, Hermann Brugger
Podsiadło, Paweł, Sylweriusz Kosiński, Tomasz Darocha, Kinga Sałapa, Tomasz Sanak, and Hermann Brugger. The use of e-learning in medical education for mountain rescuers concerning hypothermia. High Alt Med Biol 00:000-000, 2018. OBJECTIVE: Victims of mountain accidents are often exposed to wet and cold environments which may increase the risk of hypothermia. Mountain rescuers should be able to recognize and manage hypothermia. We aimed to assess relevant knowledge in professional and volunteer mountain rescuers, as well as to evaluate the efficacy of an e-learning platform for continuing medical education...
July 16, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29989833/deceleration-capacity-of-heart-rate-after-acute-altitude-exposure
#13
Wolfgang Hamm, Lukas von Stülpnagel, Mathias Klemm, Monika Baylacher, Konstantinos D Rizas, Axel Bauer, Stefan Brunner
Hamm, Wolfgang, Lukas von Stülpnagel, Mathias Klemm, Monika Baylacher, Konstantinos D. Rizas, Axel Bauer, and Stefan Brunner. Deceleration capacity of heart rate after acute altitude exposure. High Alt Med Biol 00:000-000, 2018. BACKGROUND: The autonomic nervous system plays a crucial role in adaptive changes after high-altitude exposure. Deceleration capacity (DC) of heart rate is an advanced marker of heart rate variability (HRV) that predominantly reflects the vagal activity of the cardiac autonomic nervous system...
July 10, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29957066/is-high-altitude-a-risk-factor-in-development-of-herpes-zoster
#14
G K Singh, Mahendra Singh Deora, Rajan Grewal, A Kushwaha, Sukhmeet Minhas
Singh G.K., Mahendra Singh Deora, Rajan Grewal, A. Kushwaha, and Sukhmeet Minhas, Is high altitude a risk factor in development of herpes zoster? High Alt Med Biol. 00:000-000, 2018. BACKGROUND: Old age immune-compromised states are known to increase the risk of herpes zoster (HZ). The aim of this study was to find out whether arrival into high altitude poses a risk for the development of HZ in lowlanders. METHODS: A retrospective study of 173 cases of HZ was carried out between January 1, 2005 and December 31, 2010 in people working at high altitude areas of Leh...
June 29, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29957064/additive-effects-of-intermittent-hypobaric-hypoxia-and-endurance-training-on-bodyweight-food-intake-and-oxygen-consumption-in-rats
#15
Ignacio Cabrera-Aguilera, David Rizo-Roca, Elisa A Marques, Garoa Santocildes, Teresa Pagès, Gines Viscor, António A Ascensão, José Magalhães, Joan Ramon Torrella
Cabrera-Aguilera, Ignacio, David Rizo-Roca, Elisa A. Marques, Garoa Santocildes, Teresa Pagès, Gines Viscor, António A. Ascensão, José Magalhães, and Joan Ramon Torrella. Additive effects of intermittent hypobaric hypoxia and endurance training on bodyweight, food intake, and oxygen consumption in rats. High Alt Med Biol 00:000-000, 2018.-We used an animal model to elucidate the effects of an intermittent hypobaric hypoxia (IHH) and endurance exercise training (EET) protocol on bodyweight (BW), food and water intake, and oxygen consumption...
June 29, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29924643/diabetes-related-knowledge-of-polish-national-mountain-leaders
#16
Katarzyna Nabrdalik, Hanna Kwiendacz, Monika Gubała, Kinga Tyrała, Mariusz Seweryn, Andrzej Tomasik, Tomasz Sawczyn, Michał Kukla, Władysław Grzeszczak, Janusz Gumprecht
Nabrdalik, Katarzyna, Hanna Kwiendacz, Monika Gubała, Kinga Tyrała, Mariusz Seweryn, Andrzej Tomasik, Tomasz Sawczyn, Michał Kukla, Władysław Grzeszczak, and Janusz Gumprecht. Diabetes-related knowledge of Polish national mountain leaders. High Alt Med Biol 00:000-000, 2018.-Mountain trekking is a popular activity for patients with diabetes. In Poland, mountain leaders often accompany organized groups to ensure their safety during treks; we aimed to evaluate their competency in caring for diabetic clients by assessing their diabetes-related knowledge...
June 20, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29924642/increased-cytokines-at-high-altitude-lack-of-effect-of-ibuprofen-on-acute-mountain-sickness-physiological-variables-or-cytokine-levels
#17
Jenny Lundeberg, John R Feiner, Andrew Schober, Jeffrey W Sall, Helge Eilers, Philip E Bickler
Lundeberg, Jenny, John R. Feiner, Andrew Schober, Jeffrey W. Sall, Helge Eilers, and Philip E. Bickler. Increased cytokines at high altitude: lack of effect of ibuprofen on acute mountain sickness, physiological variables or cytokine levels. High Alt Med Biol. 00:000-000, 2018. INTRODUCTION: There is no consensus on the role of inflammation in high-altitude acclimatization. AIMS: To determine the effects of a nonsteroidal anti-inflammatory drug (ibuprofen 400 mg every 8 hours) on blood cytokines, acclimatization, acute mountain sickness (AMS, Lake Louise Score), and noninvasive oxygenation in brain and muscle in healthy volunteers...
June 20, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29889556/urinary-alpha-1-acid-glycoprotein-is-a-sensitive-marker-of-glomerular-protein-leakage-at-altitude
#18
Ben J Talks, Susie B Bradwell, John Delamere, Will Rayner, Alex Clarke, Chris T Lewis, Owen D Thomas, Arthur R Bradwell
Talks, Ben J., Susie B. Bradwell, John Delamere, Will Rayner, Alex Clarke, Chris T. Lewis, Owen D. Thomas, and Arthur R. Bradwell. Urinary alpha-1-acid glycoprotein is a sensitive marker of glomerular protein leakage at altitude. High Alt Med Biol 00:000-000, 2018. Proteinuria is an established feature of ascent to altitude and may be caused by a loss of negative charges on glomerular capillary walls (GCWs). To test this hypothesis, we measured two similar sized but oppositely charged proteins in urine: negatively charged alpha-1-acid glycoprotein (α1-AGP, 41-43 kDa) and positively charged dimeric lambda free light chains (λ-FLCs, 50 kDa)...
June 11, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29939783/the-effect-of-hypoxia-on-cardiovascular-disease-friend-or-foe
#19
Jainy J Savla, Benjamin D Levine, Hesham A Sadek
Savla, Jainy J., Benjamin D. Levine, and Hesham A. Sadek. The effect of hypoxia on cardiovascular disease: Friend or foe? High Alt Med Biol. 19:124-130, 2018.-Over 140 million people reside at altitudes exceeding 2500 m across the world, resulting in exposure to atmospheric (hypobaric) hypoxia. Whether this chronic exposure is beneficial or detrimental to the cardiovascular system, however, is uncertain. On one hand, multiple studies have suggested a protective effect of living at moderate and high altitudes for cardiovascular risk factors and cardiovascular disease (CVD) events...
June 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29741971/impact-of-sleeping-altitude-on-symptoms-of-acute-mountain-sickness-on-mt-fuji
#20
Masahiro Horiuchi, Tadashi Uno, Junko Endo, Yoko Handa, Tatsuya Hasegawa
Horiuchi, Masahiro, Tadashi Uno, Junko Endo, Yoko Handa, and Tatsuya Hasegawa. Impact of sleeping altitude on symptoms of acute mountain sickness on Mt. Fuji. High Alt Med Biol. 19:193-200, 2018. AIMS: We sought to investigate the factors influencing acute mountain sickness (AMS) on Mt. Fuji in Japan, in particular, to assess the effects of sleeping altitude, by means of a questionnaire survey. This study involved 1932 participants who climbed Mt. Fuji, and obtained information regarding sex, age, and whether participants stayed at the mountain lodges...
June 2018: High Altitude Medicine & Biology
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