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High Altitude Medicine & Biology

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https://www.readbyqxmd.com/read/30010429/the-use-of-e-learning-in-medical-education-for-mountain-rescuers-concerning-hypothermia
#1
Paweł Podsiadło, Sylweriusz Kosiński, Tomasz Darocha, Kinga Sałapa, Tomasz Sanak, Hermann Brugger
Podsiadło, Paweł, Sylweriusz Kosiński, Tomasz Darocha, Kinga Sałapa, Tomasz Sanak, and Hermann Brugger. The use of e-learning in medical education for mountain rescuers concerning hypothermia. High Alt Med Biol 00:000-000, 2018. OBJECTIVE: Victims of mountain accidents are often exposed to wet and cold environments which may increase the risk of hypothermia. Mountain rescuers should be able to recognize and manage hypothermia. We aimed to assess relevant knowledge in professional and volunteer mountain rescuers, as well as to evaluate the efficacy of an e-learning platform for continuing medical education...
July 16, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29989833/deceleration-capacity-of-heart-rate-after-acute-altitude-exposure
#2
Wolfgang Hamm, Lukas von Stülpnagel, Mathias Klemm, Monika Baylacher, Konstantinos D Rizas, Axel Bauer, Stefan Brunner
Hamm, Wolfgang, Lukas von Stülpnagel, Mathias Klemm, Monika Baylacher, Konstantinos D. Rizas, Axel Bauer, and Stefan Brunner. Deceleration capacity of heart rate after acute altitude exposure. High Alt Med Biol 00:000-000, 2018. BACKGROUND: The autonomic nervous system plays a crucial role in adaptive changes after high-altitude exposure. Deceleration capacity (DC) of heart rate is an advanced marker of heart rate variability (HRV) that predominantly reflects the vagal activity of the cardiac autonomic nervous system...
July 10, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29957066/is-high-altitude-a-risk-factor-in-development-of-herpes-zoster
#3
G K Singh, Mahendra Singh Deora, Rajan Grewal, A Kushwaha, Sukhmeet Minhas
Singh G.K., Mahendra Singh Deora, Rajan Grewal, A. Kushwaha, and Sukhmeet Minhas, Is high altitude a risk factor in development of herpes zoster? High Alt Med Biol. 00:000-000, 2018. BACKGROUND: Old age immune-compromised states are known to increase the risk of herpes zoster (HZ). The aim of this study was to find out whether arrival into high altitude poses a risk for the development of HZ in lowlanders. METHODS: A retrospective study of 173 cases of HZ was carried out between January 1, 2005 and December 31, 2010 in people working at high altitude areas of Leh...
June 29, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29957064/additive-effects-of-intermittent-hypobaric-hypoxia-and-endurance-training-on-bodyweight-food-intake-and-oxygen-consumption-in-rats
#4
Ignacio Cabrera-Aguilera, David Rizo-Roca, Elisa A Marques, Garoa Santocildes, Teresa Pagès, Gines Viscor, António A Ascensão, José Magalhães, Joan Ramon Torrella
Cabrera-Aguilera, Ignacio, David Rizo-Roca, Elisa A. Marques, Garoa Santocildes, Teresa Pagès, Gines Viscor, António A. Ascensão, José Magalhães, and Joan Ramon Torrella. Additive effects of intermittent hypobaric hypoxia and endurance training on bodyweight, food intake, and oxygen consumption in rats. High Alt Med Biol 00:000-000, 2018.-We used an animal model to elucidate the effects of an intermittent hypobaric hypoxia (IHH) and endurance exercise training (EET) protocol on bodyweight (BW), food and water intake, and oxygen consumption...
June 29, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29924643/diabetes-related-knowledge-of-polish-national-mountain-leaders
#5
Katarzyna Nabrdalik, Hanna Kwiendacz, Monika Gubała, Kinga Tyrała, Mariusz Seweryn, Andrzej Tomasik, Tomasz Sawczyn, Michał Kukla, Władysław Grzeszczak, Janusz Gumprecht
Nabrdalik, Katarzyna, Hanna Kwiendacz, Monika Gubała, Kinga Tyrała, Mariusz Seweryn, Andrzej Tomasik, Tomasz Sawczyn, Michał Kukla, Władysław Grzeszczak, and Janusz Gumprecht. Diabetes-related knowledge of Polish national mountain leaders. High Alt Med Biol 00:000-000, 2018.-Mountain trekking is a popular activity for patients with diabetes. In Poland, mountain leaders often accompany organized groups to ensure their safety during treks; we aimed to evaluate their competency in caring for diabetic clients by assessing their diabetes-related knowledge...
June 20, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29924642/increased-cytokines-at-high-altitude-lack-of-effect-of-ibuprofen-on-acute-mountain-sickness-physiological-variables-or-cytokine-levels
#6
Jenny Lundeberg, John R Feiner, Andrew Schober, Jeffrey W Sall, Helge Eilers, Philip E Bickler
Lundeberg, Jenny, John R. Feiner, Andrew Schober, Jeffrey W. Sall, Helge Eilers, and Philip E. Bickler. Increased cytokines at high altitude: lack of effect of ibuprofen on acute mountain sickness, physiological variables or cytokine levels. High Alt Med Biol. 00:000-000, 2018. INTRODUCTION: There is no consensus on the role of inflammation in high-altitude acclimatization. AIMS: To determine the effects of a nonsteroidal anti-inflammatory drug (ibuprofen 400 mg every 8 hours) on blood cytokines, acclimatization, acute mountain sickness (AMS, Lake Louise Score), and noninvasive oxygenation in brain and muscle in healthy volunteers...
June 20, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29889556/urinary-alpha-1-acid-glycoprotein-is-a-sensitive-marker-of-glomerular-protein-leakage-at-altitude
#7
Ben J Talks, Susie B Bradwell, John Delamere, Will Rayner, Alex Clarke, Chris T Lewis, Owen D Thomas, Arthur R Bradwell
Talks, Ben J., Susie B. Bradwell, John Delamere, Will Rayner, Alex Clarke, Chris T. Lewis, Owen D. Thomas, and Arthur R. Bradwell. Urinary alpha-1-acid glycoprotein is a sensitive marker of glomerular protein leakage at altitude. High Alt Med Biol 00:000-000, 2018. Proteinuria is an established feature of ascent to altitude and may be caused by a loss of negative charges on glomerular capillary walls (GCWs). To test this hypothesis, we measured two similar sized but oppositely charged proteins in urine: negatively charged alpha-1-acid glycoprotein (α1-AGP, 41-43 kDa) and positively charged dimeric lambda free light chains (λ-FLCs, 50 kDa)...
June 11, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29847151/pupil-involving-third-cranial-nerve-paresis-at-high-altitude
#8
Preston H Blomquist
Blomquist, Preston H. Pupil-involving third cranial nerve paresis at high altitude. High Alt Med Biol 00:000-000, 2018. Although sixth cranial nerve palsies are a well-recognized entity at high altitude, other cranial nerve palsies due to altitude are much more uncommon. A case of a 55-year-old woman is presented who flew from Dallas, Texas (elevation 176 m) to Breckenridge, Colorado, where she hiked up to 3600 m above sea level. She developed a pupil-involving right third cranial nerve paresis that resolved over the next 3 months...
May 30, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29782186/excessive-erythrocytosis-and-cardiovascular-risk-in-andean-highlanders
#9
Noemí Corante, Cecilia Anza-Ramírez, Rómulo Figueroa-Mujíca, José Luis Macarlupú, Gustavo Vizcardo-Galindo, Grzegorz Bilo, Gianfranco Parati, Jorge L Gamboa, Fabiola León-Velarde, Francisco C Villafuerte
Cardiovascular diseases are the main cause of death worldwide. Life under high-altitude (HA) hypoxic conditions is believed to provide highlanders with a natural protection against cardiovascular and metabolic diseases compared with sea-level inhabitants. However, some HA dwellers become intolerant to chronic hypoxia and develop a progressive incapacitating syndrome known as chronic mountain sickness (CMS), characterized by excessive erythrocytosis (EE; Hb ≥21 g/dL in men, Hb ≥19 g/dL in women). Evidence from HA studies suggests that, in addition to CMS typical signs and symptoms, these highlanders may also suffer from metabolic and cardiovascular disorders...
May 21, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29757001/exhaled-nitric-oxide-changes-during-acclimatization-to-high-altitude-a-descriptive-study
#10
Douglas T Summerfield, Kirsten E Coffman, Bryan J Taylor, Amine N Issa, Bruce D Johnson
Summerfield, Douglas T., Kirsten E. Coffman, Bryan J. Taylor, Amine N. Issa, and Bruce D. Johnson. Exhaled nitric oxide changes during acclimatization to high altitude: a descriptive study. High Alt Med Biol. 00:000-000, 2018. AIMS: This study describes differences in the partial pressures of exhaled nitric oxide (PeNO) between subjects fully acclimatized (ACC) to 5300 m and those who have just arrived to high altitude. METHODS: PeNO was determined in eight subjects newly exposed and nonacclimatized (non-ACC) to high altitude and compared with that in nine subjects who had ACC to high altitude for 1 month...
May 14, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29733223/coping-with-hypoxia-at-high-altitude-how-lung-blood-and-brain-respond-and-cross-talk-5th-international-atacama-leh-symposium-in-san-pedro-de-atacama-march-4-9-2018-chile
#11
Edith M Schneider Gasser, Nuria Fabregas Bregolat, Markus Thiersch
No abstract text is available yet for this article.
May 7, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29939783/the-effect-of-hypoxia-on-cardiovascular-disease-friend-or-foe
#12
Jainy J Savla, Benjamin D Levine, Hesham A Sadek
Savla, Jainy J., Benjamin D. Levine, and Hesham A. Sadek. The effect of hypoxia on cardiovascular disease: Friend or foe? High Alt Med Biol. 19:124-130, 2018.-Over 140 million people reside at altitudes exceeding 2500 m across the world, resulting in exposure to atmospheric (hypobaric) hypoxia. Whether this chronic exposure is beneficial or detrimental to the cardiovascular system, however, is uncertain. On one hand, multiple studies have suggested a protective effect of living at moderate and high altitudes for cardiovascular risk factors and cardiovascular disease (CVD) events...
June 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29741971/impact-of-sleeping-altitude-on-symptoms-of-acute-mountain-sickness-on-mt-fuji
#13
Masahiro Horiuchi, Tadashi Uno, Junko Endo, Yoko Handa, Tatsuya Hasegawa
Horiuchi, Masahiro, Tadashi Uno, Junko Endo, Yoko Handa, and Tatsuya Hasegawa. Impact of sleeping altitude on symptoms of acute mountain sickness on Mt. Fuji. High Alt Med Biol. 19:193-200, 2018. AIMS: We sought to investigate the factors influencing acute mountain sickness (AMS) on Mt. Fuji in Japan, in particular, to assess the effects of sleeping altitude, by means of a questionnaire survey. This study involved 1932 participants who climbed Mt. Fuji, and obtained information regarding sex, age, and whether participants stayed at the mountain lodges...
June 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29717894/amputees-at-high-altitude-the-potentially-sticky-issue-of-thrombophilia
#14
Benjamin S Stacey, Lewis Fall, David Shearer, Martin Steggall, Ian W Williams, Michael H Lewis, Damian Miles Bailey
No abstract text is available yet for this article.
June 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29683363/cardiovascular-autonomic-response-to-orthostatic-stress-under-hypoxia-in-patients-with-spinal-cord-injury
#15
Shu-Chun Huang, Kuo-Cheng Liu, Alice M K Wong, Shih-Chieh Chang, Jong-Shyan Wang
Huang, Shu-Chun, Kuo-Cheng Liu, Alice M.K. Wong, Shih-Chieh Chang, and Jong-Shyan Wang. Cardiovascular autonomic response to orthostatic stress under hypoxia in patients with spinal cord injury. High Alt Med Biol. 19:201-207, 2018. AIMS: Determining whether systemic hypoxia aggravates the severity of autonomic cardiovascular dysfunction in orthostatic stress among patients with spinal cord injuries (SCIs). METHODS: Twenty-four male patients with chronic SCI whose neurological levels were above T6 were recruited...
June 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29630402/prostatic-specific-antigen-levels-in-men-from-two-andean-cities-of-peru
#16
Diana E Alcantara-Zapata, Gustavo F Gonzales, Paulina Pino
No abstract text is available yet for this article.
April 9, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29620950/a-systematic-review-and-meta-analysis-reveals-altered-drug-pharmacokinetics-in-humans-during-acute-exposure-to-terrestrial-high-altitude-clinical-justification-for-dose-adjustment
#17
Damian Miles Bailey, Benjamin S Stacey, Mark Gumbleton
OBJECTIVE: While physiological responses during acute ascent to terrestrial high altitude (HA) have the potential to alter the pharmacokinetics (PKs) that define absorption and disposition of medicinal drugs, there have been no systematic reviews and meta-analyses performed to date. METHODS: We conducted a systematic literature search in June 2017 using NCBI PubMed, EMBASE, Web of Science, and Ovid MEDLINE databases to identify relevant observational studies. Studies were deemed eligible based on the following criteria: (1) participants: healthy, nonacclimatized male or female lowlanders (born and bred at sea level) and (2) environment: exposure to low altitude (LA, ≤600 m), followed by terrestrial high altitude (HA, ≤24 hours to ≥2500 m), the time course specifically selected to avoid interpretive complications associated with erythrocytosis...
April 5, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29608374/exploration-of-acute-phase-proteins-and-inflammatory-cytokines-in-early-stage-diagnosis-of-acute-mountain-sickness
#18
Chi Wang, Hui Jiang, Jinyan Duan, Jingwen Chen, Qi Wang, Xiaoting Liu, Chengbin Wang
Wang, Chi, Hui Jiang, Jinyan Duan, Jingwen Chen, Qi Wang, Xiaoting Liu, and Chengbin Wang. Exploration of acute phase proteins and inflammatory cytokines in early stage diagnosis of acute mountain sickness. High Alt Med Biol. 00: 000-000, 2018. BACKGROUND: Early diagnosis of acute mountain sickness (AMS) is currently based on personal appreciation of the severity of symptoms. A more objective method to diagnose AMS is required. Inflammatory cytokines and acute phase proteins have been reported to be different at high altitude...
April 2, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29608373/cold-susceptibility-of-digit-stumps-resulting-from-amputation-after-freezing-cold-injury-in-elite-alpinists
#19
Jurij Gorjanc, Shawnda A Morrison, Rok Blagus, Igor B Mekjavic
Gorjanc, Jurij, Shawnda A. Morrison, Rok Blagus, and Igor B. Mekjavic. Cold susceptibility of digit stumps resulting from amputation after freezing cold injury in elite alpinists. High Alt Med Biol. 16: 000-000, 2018. AIM: The aim of the study was to assess whether previous freezing cold injury in fingers and/or toes might predispose alpinists to greater risk of further freezing cold injury, primarily due to a greater vasoconstrictor response to cold, resulting in a lower perfusion, reflected in lower skin temperature...
April 2, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29565692/a-case-of-subacute-infantile-mountain-sickness-in-a-kyrgyz-child
#20
Kubatbek Muratali Uulu, Meerim Cholponbaeva, Melis Duishobaev, Aidana Toktosunova, Abdirashit Maripov, Akylbek Sydykov, Akpay Sarybaev
Muratali Uulu, Kubatbek, Meerim Cholponbaeva, Melis Duishobaev, Aidana Toktosunova, Abdirashit Maripov, Akylbek Sydykov, and Akpay Sarybaev. A case of subacute infantile mountain sickness in a Kyrgyz child. High Alt Med Biol. 00: 000-000, 2018.-Subacute infantile mountain sickness (SIMS) is a syndrome of severe pulmonary hypertension and right heart failure that develops in infants born in the lowlands and subsequently brought to live at high altitudes. Earlier postmortem studies have demonstrated significant remodeling of small pulmonary arteries as well as right ventricular hypertrophy and dilatation...
March 22, 2018: High Altitude Medicine & Biology
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