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High Altitude Medicine & Biology

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https://www.readbyqxmd.com/read/28333563/effect-of-high-altitude-exposure-on-intraocular-pressure-using-goldmann-applanation-tonometry
#1
Gabriel Willmann, Kai Schommer, Maximilian Schultheiss, M Dominik Fischer, Karl-Ulrich Bartz-Schmidt, Florian Gekeler, Andreas Schatz
Willmann, Gabriel, Kai Schommer, Maximilian Schultheiss, M. Dominik Fischer, Karl-Ulrich Bartz-Schmidt, Florian Gekeler, and Andreas Schatz. Effect of high altitude exposure on intraocular pressure using Goldmann applanation tonometry. High Alt Med Biol. 00:000-000, 2017. AIMS: The aim of the study was to quantify changes of intraocular pressure (IOP) during exposure to 4559 m using the state-of-the-art method of Goldmann applanation tonometry for IOP measurement and to detect correlations between IOP and acute mountain sickness (AMS) in a prospective manner...
March 23, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28326844/oxidative-stress-in-acute-hypobaric-hypoxia
#2
Sebastián Irarrázaval, Claudio Allard, Juan Campodónico, Druso Pérez, Pablo Strobel, Luis Vásquez, Inés Urquiaga, Guadalupe Echeverría, Federico Leighton
Irarrázaval, Sebastián, Claudio Allard, Juan Campodónico, Druso Pérez, Pablo Strobel, Luis Vásquez, Inés Urquiaga, Guadalupe Echeverría, and Federico Leighton. Oxidative stress in acute hypobaric hypoxia. High Alt Med Biol. 00:000-000, 2017.-The effects of acute hypobaric hypoxia endured by mountaineers were studied, specifically as evidenced by acute mountain sickness (AMS) and oxidative stress damage. Ten male volunteers were exposed to acute hypobaric hypoxia, and AMS was evaluated through arterial oxygen saturation (SaO2), cardiac rate, and the Lake Louise Score (LLS)...
March 22, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28323448/effects-of-chronic-ghrelin-treatment-on-hypoxia-induced-brain-oxidative-stress-and-inflammation-in-a-rat-normobaric-chronic-hypoxia-model
#3
Hasan Omrani, Mohammad Reza Alipour, Fereshteh Farajdokht, Hadi Ebrahimi, Mehran Mesgari Abbasi, Gisou Mohaddes
AIM: This study aimed to evaluate the probable antioxidant effects of ghrelin in the brain and serum and its effect on tumor necrosis factor-alpha (TNF-α) levels in the brain in a model of chronic systemic hypoxia in rats. METHODS: Systemic hypoxia was induced by a normobaric hypoxic chamber (O2 11%) for ten days. Adult male Wistar rats were divided into control (C), chronic ghrelin (80 μg/kg/10 days) (Ghr), chronic hypoxia (CH), and CH and ghrelin (80 μg/kg/ip/10 days) (CH + Gh) groups...
March 21, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28294639/physiological-changes-to-the-cardiovascular-system-at-high-altitude-and-its-effects-on-cardiovascular-disease
#4
Callum James Riley, Matthew Gavin
Riley, Callum James, and Matthew Gavin. Physiological changes to the cardiovascular system at high altitude and its effects on cardiovascular disease. High Alt Med Biol. 00:000-000, 2017.-The physiological changes to the cardiovascular system in response to the high altitude environment are well understood. More recently, we have begun to understand how these changes may affect and cause detriment to cardiovascular disease. In addition to this, the increasing availability of altitude simulation has dramatically improved our understanding of the physiology of high altitude...
March 15, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28256920/are-permanent-residents-of-high-altitude-fully-adapted-to-their-hypoxic-environment
#5
John B West
West, John B. Are permanent residents of high altitude fully adapted to their hypoxic environment? High Alt Med Biol 00:000-000, 2017. Millions of people live permanently at high altitude and many have been there for generations. It is sometimes claimed that these people have completely adapted to their environment, and certainly some remarkable genetic adaptations have recently been described. However there is now strong evidence that permanent residents are not completely adapted to the high altitude in the sense that they have fully compensated for the environmental hypoxia...
March 3, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28128652/extensive-microhemorrhages-of-the-cerebellar-peduncles-after-high-altitude-cerebral-edema
#6
Jacqueline Pichler Hefti, Philipp Hoigné-Perret, Raimund Kottke
Pichler Hefti, Jacqueline, Philipp Hoigné-Perret, and Raimund Kottke. Extensive microhemorrhages of the cerebellar peduncles after high-altitude cerebral edema. High Alt Med Biol 00:000-000, 2017.-Neuromagnetic resonance imaging (MRI) of subjects who suffered from high-altitude cerebral edema (HACE) typically shows cerebral microhemorrhages (MH) of the corpus callosum, in particular the splenium, and supratentorial white matter. This is a case report of a 43-year-old male, who suffered from unusually prolonged severe ataxia and amnesia after having been rescued during the ascent to Mount Everest at 6400 m...
January 27, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28306414/cross-sectional-comparison-of-sleep-disordered-breathing-in-native-peruvian-highlanders-and-lowlanders
#7
Luu V Pham, Christopher Meinzen, Rafael S Arias, Noah G Schwartz, Adi Rattner, Catherine H Miele, Philip L Smith, Hartmut Schneider, J Jaime Miranda, Robert H Gilman, Vsevolod Y Polotsky, William Checkley, Alan R Schwartz
Pham, Luu V., Christopher Meinzen, Rafael S. Arias, Noah G. Schwartz, Adi Rattner, Catherine H. Miele, Philip L. Smith, Hartmut Schneider, J. Jaime Miranda, Robert H. Gilman, Vsevolod Y. Polotsky, William Checkley, and Alan R. Schwartz. Cross-sectional comparison of sleep-disordered breathing in native Peruvian highlanders and lowlanders. High Alt Med Biol. 18:11-19, 2017. BACKGROUND: Altitude can accentuate sleep disordered breathing (SDB), which has been linked to cardiovascular and metabolic diseases...
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28306413/response-to-pun-re-chronic-intermittent-hypoxia-and-blood-pressure-is-there-risk-for-hypertension-in-healthy-individuals
#8
Denis Vinnikov
No abstract text is available yet for this article.
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28306412/periodic-high-altitude-exposure-and-chronic-intermittent-hypoxia-are-they-the-same
#9
Matiram Pun
No abstract text is available yet for this article.
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28266873/alteration-of-spontaneous-brain-activity-after-hypoxia-reoxygenation-a-resting-state-fmri-study
#10
Jiaxing Zhang, Ji Chen, Cunxiu Fan, Jinqiang Li, Jianzhong Lin, Tianhe Yang, Ming Fan
Zhang, Jiaxing, Ji Chen, Cunxiu Fan, Jinqiang Li, Jianzhong Lin, Tianhe Yang, and Ming Fan. Alteration of spontaneous brain activity after hypoxia-reoxygenation: A resting-state fMRI study. High Alt Med Biol. 18:20-26, 2017.-The present study was designed to investigate the effect of hypoxia-reoxygenation on the spontaneous neuronal activity in brain. Sixteen sea-level (SL) soldiers (20.5 ± 0.7 years), who garrisoned the frontiers in high altitude (HA) (2300-4400 m) for two years and subsequently descended to sea level for one to seven days, were recruited...
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28135110/the-influence-of-17-hours-of-normobaric-hypoxia-on-parallel-adjustments-in-exhaled-nitric-oxide-and-airway-function-in-lowland-healthy-adults
#11
Erik H Van Iterson, Eric M Snyder, Bruce D Johnson
Van Iterson, Erik H., Eric M. Snyder, and Bruce D. Johnson. The influence of 17 hours of normobaric hypoxia on parallel adjustments in exhaled nitric oxide and airway function in lowland healthy adults. High Alt Med Biol. 18:1-10, 2017.-Currently, there is a disparate understanding of the role that normobaric hypoxia plays in affecting nitric oxide (NO) measured in exhaled air (eNO) and airway function in lowland healthy adults. Compared to normobaric normoxia, this study aimed to test the effect of 17 hours of normobaric hypoxia on relationships between eNO and airway function in healthy adults...
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28112542/review-of-mountain-medicine-and-technical-rescue
#12
Ken Zafren
No abstract text is available yet for this article.
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28106468/proceedings-of-bmres-altitude-medicine-conference-november-26th-2016-birmingham-united-kingdom
#13
Lauren E Gault, Christopher T Lewis, Hannah E Lock
No abstract text is available yet for this article.
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28072549/free-flight-physiology-paragliding-and-the-study-of-extreme-altitude
#14
Matt Wilkes, Martin J MacInnis, Matthew J Witt, Michael Vergalla, Mathieu Verschave Keysers, Adrian Thomas, Lucy A Hawkes
No abstract text is available yet for this article.
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28061144/long-term-health-outcomes-in-high-altitude-pulmonary-hypertension
#15
Jeffrey C Robinson, Cheryl Abbott, Christina A Meadows, Robert C Roach, Benjamin Honigman, Todd M Bull
Robinson, Jeffrey C., Cheryl Abbott, Christina A. Meadows, Robert C. Roach, Benjamin Honigman, and Todd M. Bull. Long-term health outcomes in high-altitude pulmonary hypertension. High Alt Med Biol. 18:61-66, 2017. BACKGROUND: High-altitude pulmonary hypertension (HAPH) is one of several known comorbidities that effect populations living at high altitude, but there have been no studies looking at long-term health consequences of HAPH. We aimed to determine whether HAPH during adolescence predisposes to significant pulmonary hypertension (PH) later in life, as well as identify how altitude exposure and HAPH correlate with functional class and medical comorbidities...
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28048949/on-the-significance-of-altered-drug-pharmacokinetics-pharmacodynamics-at-high-altitude
#16
Damian M Bailey
No abstract text is available yet for this article.
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28002687/surviving-without-oxygen-how-low-can-the-human-brain-go
#17
Damian M Bailey, Christopher K Willie, Ryan L Hoiland, Anthony R Bain, David B MacLeod, Maria A Santoro, Daniel K DeMasi, Andrea Andrijanic, Tanja Mijacika, Otto F Barak, Zeljko Dujic, Philip N Ainslie
Bailey, Damian M., Christopher K. Willie, Ryan L. Hoiland, Anthony R. Bain, David B. MacLeod, Maria A. Santoro, Daniel K. DeMasi, Andrea Andrijanic, Tanja Mijacika, Otto F. Barak, Zeljko Dujic, and Philip N. Ainslie. Surviving without oxygen: how low can the human brain go? High Alt Med Biol 18:73-79, 2017.-Hypoxic cerebral vasodilation is a highly conserved physiological response coupling cerebral O2 delivery (CDO2) to metabolic demand with increasingly important roles identified for the red blood cell (sensor) and nitric oxide (effector)...
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/27996304/corneal-thickness-in-highlanders
#18
Sagarika Patyal, Amit Arora, Arun Yadav, Vijay K Sharma
Patyal, Sagarika, Amit Arora, Arun Yadav, and Vijay K. Sharma. Corneal thickness in highlanders. High Alt Med Biol. 18:56-60, 2017. BACKGROUND: Corneal thickness is an important parameter with diagnostic and therapeutic implications. Various studies have highlighted increase in corneal thickness in lowlanders on ascending to high altitude. However, there are no studies in the published literature pertaining to corneal thickness of the highlanders who are inhabitants of such altitudes...
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/27996303/re-increased-cardiometabolic-risk-and-worsening-hypoxemia-at-high-altitude-by-miele-et-al
#19
Offdan D Narvaez-Guerra, Karela Herrera-Enriquez
No abstract text is available yet for this article.
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/27912037/avalanche-accidents-causing-fatalities-are-they-any-different-in-the-summer
#20
Mathieu Pasquier, Olivier Hugli, Alexandre Kottmann, Frank Techel
Pasquier, Mathieu, Olivier Hugli, Alexandre Kottmann, and Frank Techel. Avalanche accidents causing fatalities: are they any different in the summer? High Alt Med Biol. 18:67-72, 2017. AIMS: This retrospective study investigated the epidemiology of summer avalanche accidents that occurred in Switzerland and caused at least one fatality between 1984 and 2014. Summer avalanche accidents were defined as those that occurred between June 1st and October 31st. RESULTS: Summer avalanches caused 21 (4%) of the 482 avalanches with at least one fatality occurring during the study period, and 40 (6%) of the 655 fatalities...
March 2017: High Altitude Medicine & Biology
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