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Current Urology Reports

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https://www.readbyqxmd.com/read/29130146/recent-developments-in-the-search-for-urinary-biomarkers-in-bladder-cancer
#1
REVIEW
Aaron Leiblich
PURPOSE OF REVIEW: This review aims to evaluate research surrounding the utility of urinary biomarkers to detect bladder cancer and predict recurrence. RECENT FINDINGS: Recent research has focussed on the evaluation of genetic markers found in urine to provide diagnostic and prognostic information. Furthermore, the isolation and characterisation of extracellular vesicles (EVs) from the urine patients with bladder cancer provide an exciting new development in biomarker research that is set to expand in the coming years...
November 13, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29116405/systematic-review-of-studies-reporting-positive-surgical-margins-after-bladder-neck-sparing-radical-prostatectomy
#2
REVIEW
Mariangela Bellangino, Clare Verrill, Tom Leslie, Richard W Bell, Freddie C Hamdy, Alastair D Lamb
PURPOSE OF REVIEW: Bladder neck preservation (BNP) during radical prostatectomy (RP) has been proposed as a method to improve early recovery of urinary continence after radical prostatectomy. However, there is concern over a possible increase in the risk of positive surgical margins and prostate cancer recurrence rate. A recent systematic review and meta-analysis reported improved early recovery and overall long-term urinary continence without compromising oncologic control. The aim of our study was to perform a critical review of the literature to assess the impact on bladder neck and base margins after bladder neck sparing radical prostatectomy...
November 7, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29081016/a-review-of-imaging-modalities-used-in-the-diagnosis-and-management-of-scrotal-trauma
#3
REVIEW
Alexis Wang, Ian Stormont, M Minhaj Siddiqui
Genitourinary tract injuries account for 3 to 10% of trauma patients, and scrotal trauma is particularly prevalent in males 10 to 30 years of age. Prompt diagnosis and timely surgical intervention are essential to prevent future complications of infertility, delayed orchiectomy, infection, and testicular atrophy. While clinical examination provides valuable information, it may be inconclusive due to soft tissue swelling and difficult to perform due to testicular pain with palpation. Conversely, testicular rupture does not always present with pain or tenderness...
October 28, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29064054/histoscanning-tm-to-detect-and-characterize-prostate-cancer-a-review-of-existing-literature
#4
REVIEW
James S Wysock, Alex Xu, Clement Orczyk, Samir S Taneja
PURPOSE OF REVIEW: The widely acknowledged limitations of the standard prostate cancer (PCa) diagnostic paradigm have provided an impetus to explore novel imaging modalities to diagnose, localize, and risk stratify PCa. As the body of literature focused on HistoScanning™(HS) grows, there is need for a comprehensive review of the clinical efficacy of this technology. RECENT FINDINGS: Eighteen original, English language articles were found to adequately study the use of HistoScanning™ for prostate cancer diagnosis in the clinical setting...
October 24, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29046983/holmium-laser-enucleation-of-the-prostate-patient-selection-and-outcomes
#5
REVIEW
Joseph M Kuebker, Nicole L Miller
PURPOSE OF REVIEW: Holmium laser enucleation of the prostate (HoLEP) is a proven technique to alleviate bladder outlet obstruction (BOO) from benign prostatic hyperplasia (BPH). Herein, we review factors relevant to selecting patients who will benefit from this procedure and expected outcomes. RECENT FINDINGS: New randomized trials have validated the excellent outcomes achieved by HoLEP in the management of BOO from BPH. Its success has been reproduced in a diverse array of patients including those on anticoagulation, with detrusor underactivity/acontractility, prostate cancer, and in the retreatment setting...
October 19, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29046995/aquablation-of-the-prostate-for-symptomatic-benign-prostatic-hyperplasia-early-results
#6
REVIEW
Omid Yassaie, Joshua A Silverman, Peter J Gilling
Aquablation is a novel technique for the surgical management of bladder outlet obstruction secondary to benign prostatic hyperplasia. Following first-in-man studies, a multicenter trial was conducted with results now out to 1 year. Aquablation resulted in a mean International Prostate Symptom Score improvement of 16 points (p < 0.01) and a mean maximum urinary flow rate increase from 8.7 to 18.3 ml/s (p < 0.01) at 12 months. Due to the precise prostate mapping, aquablation has also demonstrated favorable sexual and urinary outcomes with no new erectile dysfunction, retrograde ejaculation, or urinary incontinence as often experienced with other techniques...
October 18, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29046986/predictability-and-practicality-of-image-based-scoring-systems-for-patient-assessment-and-outcome-stratification-during-percutaneous-nephrolithotomy-a-contemporary-update
#7
REVIEW
Linda My Huynh, Erica Huang, Roshan M Patel, Zhamshid Okhunov
Preoperative nomograms offer systematic and quantitative methods to assess patient- and stone-related characteristics and their impact on successful treatment and potential risk of complication. Discrepancies in the correlation of perioperative variables to patient outcomes have led to the individual development, validation, and application of four independent scoring systems for the percutaneous nephrolithotomy: Guy's stone score, S.T.O.N.E. nephrolithometry, Clinical Research Office of the Endourology Society nomogram, and Seoul National University Renal Stone Complexity...
October 18, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29046985/new-devices-and-technologies-for-the-management-of-overactive-bladder
#8
REVIEW
Juan M Guzman-Negron, Howard B Goldman
PURPOSE OF REVIEW: Overactive bladder (OAB) affects millions of people in the USA and has a significant impact on their quality of life. Despite having a number of safe and effective ways of managing refractory OAB patients, there are many promising new technologies actively being studied and developed for the treatment of this population. This review examines current new devices and technologies under study for the treatment of OAB. RECENT FINDINGS: Modifications to already established therapies such as sacral nerve stimulation (SNS) or tibial nerve stimulation (TNS) are currently being studied for refractory OAB...
October 18, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29046984/spatial-tracking-of-targeted-prostate-biopsy-locations-moving-towards-effective-focal-partial-prostate-gland-ablation-with-improved-treatment-planning
#9
REVIEW
Steven Sidelsky, Shaan Setia, Srinivas Vourganti
The ability to selectively characterize, localize, and predict the specific areas of the prostate gland which harbor the worst biologic behavior is requisite for optimal prostate cancer therapy, especially in the emerging field of partial prostate gland ablation (focal therapy). In this manuscript, we highlight contemporary techniques in target tracking for focal therapy planning. Multiparametric magnetic resonance imaging has emerged as a dominant strategy to localize biopsy sites most likely to contain high-grade lesions...
October 18, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29046982/ureteroscopy-for-stone-disease-in-paediatric-population-is-safe-and-effective-in-medium-volume-and-high-volume-centres-evidence-from-a-systematic-review
#10
REVIEW
Shazna Rob, Patrick Jones, Amelia Pietropaolo, Stephen Griffin, Bhaskar K Somani
PURPOSE OF REVIEW: The incidence of urinary stone disease among the paediatric population is increasing. Whilst there has been a rise in the number of original studies published on ureteroscopy (URS) in children, critical review still remains under-reported. RECENT FINDINGS: A Cochrane style systematic review was performed to identify all original articles on URS (minimum of 25 cases) for stone disease in paediatric patients between Jan. 1996 and Dec. 2016. Based on the number of reported cases, centres were divided into medium (25-49 cases) and high (≥ 50 cases) volume studies...
October 18, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28780635/convective-radiofrequency-water-vapor-thermal-therapy-with-rez%C3%A5-m-system
#11
REVIEW
Sevann Helo, Bradley Holland, Kevin T McVary
PURPOSE: Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) are amongst the most commonly treated conditions by urologists. Minimally invasive therapies for the treatment of BPH/LUTS have garnered increased interest as new technology has emerged, improving durability, efficacy, and safety. This paper reviews the most recent literature regarding water vapor therapy, a convective thermal therapy that ablates prostatic tissue. RECENT FINDINGS: The current literature includes a pilot study of 65 men and a randomized controlled trial (RCT) of 197 men investigating the efficacy and safety profile of water vapor therapy up to 2 years...
October 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28780634/holmium-laser-enucleation-of-the-prostate-in-patients-requiring-anticoagulation
#12
REVIEW
Marcelino Rivera, Amy Krambeck, James Lingeman
PURPOSE OF REVIEW: This is to evaluate and discuss the literature surrounding holmium laser enucleation of the prostate (HoLEP) in patients on anticoagulation. RECENT FINDINGS: The relationship of benign prostatic hyperplasia (BPH) to bothersome lower urinary tract symptoms (LUTS) is well established with a majority of men over the age of 60 having significant symptoms. Patients with severe enough symptoms often require surgery and with cardiovascular disease ranking as the primary cause of death in the USA, a growing number will be taking antiplatelet (AP) or anticoagulation (AC) for primary or secondary prevention of disease...
October 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28776126/management-of-urethral-stricture-and-bladder-neck-contracture-following-primary-and-salvage-treatment-of-prostate-cancer
#13
REVIEW
Brendan Michael Browne, Alex J Vanni
PURPOSE OF REVIEW: This article discusses the incidence, evaluation, and treatment of bladder outlet obstruction from urethral stricture, vesicourethral anastomotic stricture, and bladder neck contracture following primary and salvage treatment of prostate cancer. RECENT FINDINGS: Rates of stenosis after prostate cancer treatment appear similar across all primary treatment modalities including radical prostatectomy, radiation therapy, cryoablation, and high-intensity focused ultrasound in contemporary series...
October 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28766115/is-there-a-role-for-preoperative-5-alpha-reductase-inhibitors-in-reducing-prostate-vascularity-and-blood-loss
#14
REVIEW
Matthew Bruha, Charles Welliver
Benign prostatic hyperplasia (BPH) and the related medical problems are a major burden as health care costs and as a cause of patient morbidity. The introduction of medical therapy largely offered an alternative to surgical therapy, and these medications have been linked with multiple positive BPH-related outcomes. With ubiquitous use, however, a variety of adverse side effects and unsupported claims to these medications have been reported both in scientific literature and popular press. The use of 5 alpha reductase inhibitors (5ARIs) to reduce recurrent bleeding due to BPH is a reasonable option for men with recurrent trips to the physician or hospital...
October 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28965315/surgical-techniques-for-managing-post-prostatectomy-erectile-dysfunction
#15
REVIEW
Fabio Castiglione, David J Ralph, Asif Muneer
PURPOSE OF REVIEW: Due to the increasing numbers of radical prostatectomies (RP) performed for prostate cancer, a substantial number of patients are now suffering from post-operative erectile dysfunction (ED). The aim of this study is to summarize the current literature on surgical techniques for managing post-prostatectomy erectile dysfunction. RECENT FINDINGS: The PubMed database was searched for English-language articles published up to Jan 2017 using the following search terms: "prostatectomy AND erectile dysfunction", "prostatectomy AND penile prostheses", and "prostatectomy AND penile implants"...
September 30, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28942572/learning-curves-for-robotic-surgery-a-review-of-the-recent-literature
#16
REVIEW
Giorgio Mazzon, Ashwin Sridhar, Gerald Busuttil, James Thompson, Senthil Nathan, Tim Briggs, John Kelly, Greg Shaw
Use of robot-assisted surgery is increasing since its advent in the 1990s. Robotic surgical training is the subject of much interest. Robotic technology would seem to facilitate training allowing more rapid attainment of competence. The safety and success of a particular surgical team depends on adequacy of training of its members. A learning curve is a way of describing the changes observed in surgical outcomes with increasing experience of the surgeon and can be used to plan training programs. The majority of published papers regarding learning curves are retrospective with small numbers of surgeons with different levels of experience comparing a variety of different outcomes...
September 23, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28921390/the-state-of-men-s-health-services-in-the-veterans-health-administration
#17
REVIEW
Michael Fenstermaker, Sujay Paknikar, Amarnath Rambhatla, Dana A Ohl, Ted A Skolarus, James M Dupree
PURPOSE OF REVIEW: For many diseases that place a large burden on our health care system, men often have worse health outcomes than women. As the largest single provider of health care to men in the USA, the Veterans Health Administration (VA) has the potential to serve as leader in the delivery of improved men's health care to address these disparities. RECENT FINDINGS: The VA system has made recent strides in improving benefits for aspects of men's health that are traditionally poorly covered, such as treatment for male factor infertility...
September 18, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28900880/characterizing-indeterminate-renal-masses-with-molecular-imaging-the-role-of-99m-tc-mibi-spect-ct
#18
REVIEW
Andrew M Reynolds, Kristin Kelly Porter
PURPOSE OF REVIEW: The majority of enhancing renal masses cannot be characterized through imaging as malignant or benign; however, such characterization could save patients from unnecessary surgery and/or biopsy and associated morbidity. Herein, we review the recent literature on the emerging use of (99m)Tc-MIBI SPECT/CT in preoperative differentiation of enhancing renal masses. RECENT FINDINGS: Recent reports have shown that (99m)Tc-MIBI SPECT/CT imaging can differentiate mitochondrial-rich, benign, or indolent renal masses from renal cell carcinoma...
September 12, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28900856/incidence-and-management-of-de-novo-lower-urinary-tract-symptoms-after-pelvic-organ-prolapse-repair
#19
REVIEW
Henry Tran, Doreen E Chung
PURPOSE OF REVIEW: Pelvic organ prolapse (POP) is a significant problem with many options for surgical correction. Following prolapse surgery, de novo lower urinary tract symptoms (LUTS) are not uncommon. We review the current literature on de novo lower urinary tract symptoms following POP repair and discuss the role of urodynamics in the evaluation of the prolapse patient. RECENT FINDINGS: Patients with occult stress urinary incontinence (SUI) appear to be at higher risk of developing de novo SUI after POP repair...
September 12, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28900827/lifetime-radiation-exposure-in-patients-with-recurrent-nephrolithiasis
#20
REVIEW
Mohamed A Elkoushy, Sero Andonian
Patients presenting with nephrolithiasis often undergo repeated imaging studies before, during, and after management. Considering the significant risk of stone recurrence in primary stone-formers, repeated imaging studies are not uncommon. Cumulative effects of ionizing radiation exposure from various imaging studies could potentially increase the risk for developing cataracts and solid malignancies in urolithiasis patients. Therefore, practitioners planning or performing imaging studies with ionizing radiation are compelled to keep radiation exposure to humans and the environment as low as possible, thus strictly adhering to the ALARA (As Low as Reasonably Achievable) principles...
September 12, 2017: Current Urology Reports
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