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HPB: the Official Journal of the International Hepato Pancreato Biliary Association

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https://www.readbyqxmd.com/read/28302441/percutaneous-transhepatic-cholangiographic-endobiliary-forceps-biopsy-versus-endoscopic-ultrasound-fine-needle-aspiration-for-proximal-biliary-strictures-a-single-centre-experience
#1
Kayvan Mohkam, Yaseen Malik, Carlos Derosas, John Isaac, Ravi Marudanayagam, Homoyoon Mehrzad, Darius F Mirza, Paolo Muiesan, Keith J Roberts, Robert P Sutcliffe
BACKGROUND: Endoscopic ultrasound fine needle aspiration (EUS-FNA) and percutaneous transhepatic cholangiographic endobiliary forceps biopsy (PTC-EFB) are valid procedures for histological assessment of proximal biliary strictures (PBS), but their performances have never been compared. This study aimed to compare the diagnostic performance of these two techniques. METHOD: The diagnostic performances of EUS-FNA and PTC-EFB were compared in a retrospective cohort of patients assessed for PBS from 2011 to 2015 at a single tertiary centre...
March 13, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28292633/the-outcomes-of-the-pancreaticoduodenectomy-in-patients-aged-80-or-older-a-systematic-review-and-meta-analysis
#2
REVIEW
Sandy Y Kim, Laurence Weinberg, Christopher Christophi, Mehrdad Nikfarjam
BACKGROUND: There is an increasing needed to consider pancreaticoduodenectomy (PD) for the treatment of pancreatic and periampullary malignancy in patients aged 80 and over, given the increasing aging population. METHODS: A systematic literature search was undertaken to identify selected studies that compared the outcomes of patients aged 80 years or over to those younger undergoing PD. RESULTS: In total 18 studies were included for evaluation...
March 11, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28286045/acknowledging-the-flaws-to-advance-with-the-strengths-of-alpps
#3
LETTER
Pim B Olthof, William R Jarnagin, Thomas M van Gulik
No abstract text is available yet for this article.
March 10, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28286044/preoperative-fecal-elastase-1-is-a-useful-prognostic-marker-following-curative-resection-of-pancreatic-cancer
#4
Jin Hong Lim, Joon Seong Park, Dong Sup Yoon
BACKGROUND: The clinical relevance of fibrosis with regard to tumor progression is supported by the correlation between fibrosis and poor outcomes. Fecal elastase-1 (FE-1) level has been used to assess exocrine dysfunction of the pancreas and to predict pancreas fibrosis. The aim of this study was to assess the impact of FE-1 on the survival of pancreatic cancer patients. METHODS: Between January 2006 and December 2014, 136 patients with pancreatic adenocarcinoma underwent R0 resection at Gangnam Severance Hospital, Korea...
March 9, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28279621/high-mortality-after-alpps-for-perihilar-cholangiocarcinoma-case-control-analysis-including-the-first-series-from-the-international-alpps-registry
#5
Pim B Olthof, Robert J S Coelen, Jimme K Wiggers, Bas Groot Koerkamp, Massimo Malago, Roberto Hernandez-Alejandro, Stefan A Topp, Marco Vivarelli, Luca A Aldrighetti, Ricardo Robles Campos, Karl J Oldhafer, William R Jarnagin, Thomas M van Gulik
INTRODUCTION: Resection of perihilar cholangiocarcinoma (PHC) entails high-risk surgery with postoperative mortality reported up to 18%, even in specialized centers. The aim of this study was to compare outcomes of PHC patients who underwent associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) to patients who underwent resection without ALPPS. METHODS: All patients who underwent ALPPS for PHC were identified from the international ALPPS registry and matched controls were selected from a standard resection cohort from two centers based on future remnant liver size...
March 6, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28274661/research-considerations-in-the-evaluation-of-minimally-invasive-pancreatic-resection-mipr
#6
REVIEW
Jeffrey Barkun, William Fisher, Giana Davidson, Go Wakabayashi, Marc Besselink, Henry Pitt, Jane Holt, Steve Strasberg, Charles Vollmer, David Kooby
The IHPBA/AHPBA-sponsored 2016 minimally invasive pancreatic resection (MIPR) conference held on April 20th, 2016 included a session designed to evaluate what would be the most appropriate scientific contribution to help define the increasing role of MIPR internationally. Participants in the conference reviewed the assessment of numerous pertinent scientific designs including randomized controlled trial (RCT), pragmatic international RCT, registry-RCT, non-RCT with propensity matching, and various types of clinical registries including those aiming to create a quality improvement data system or a learning health care system...
March 5, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28268161/minimally-invasive-pancreatic-resections-cost-and-value-perspectives
#7
Kevin C Conlon, Thijs de Rooij, Jony van Hilst, Mohammad Abu Hidal, Julie Fleshman, Mark Talamonti, Tsafrir Vanounou, Richard Garfinkle, Vic Velanovich, David Kooby, Charles M Vollmer
BACKGROUND: The number of minimally invasive pancreatic resections (MIPR) performed for benign or malignant disease, have increased in recent years. However, there is limited information regarding cost/value implications. METHODS: An international conference evaluating MIPR was held during the 12th Bi-Annual International Hepato-Pancreato-Biliary Association (IHPBA) World Congress in Sao Paulo, Brazil, on April 20th, 2016. This manuscript summarizes the presentations that reviewed current topics in cost and value as they pertain to MIPR...
March 4, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28262523/outcome-of-alpps-for-perihilar-cholangiocarcinoma-case-control-analysis-including-the-first-series-from-the-international-alpps-registry
#8
LETTER
Hauke Lang, Eduardo de Santibanes, Pierre Alain Clavien
No abstract text is available yet for this article.
March 2, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28237627/utilization-of-preoperative-endoscopic-ultrasound-for-pancreatic-adenocarcinoma
#9
Ryan K Schmocker, David J Vanness, Caprice C Greenberg, Jeff A Havlena, Noelle K LoConte, Jennifer M Weiss, Heather B Neuman, Glen Leverson, Maureen A Smith, Emily R Winslow
BACKGROUND: Endoscopic ultrasound (EUS) is used for pancreatic adenocarcinoma staging and obtaining a tissue diagnosis. The objective was to determine patterns of preoperative EUS and the impact on downstream treatment. METHODS: The Surveillance, Epidemiology, and End Results (SEER) Medicare-linked database was used to identify patients with pancreatic adenocarcinoma. The staging period was the first staging procedure within 6 months of surgery until surgery. Logistic regression was used to determine factors associated with preoperative EUS...
February 22, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28233673/splenectomy-during-whole-liver-transplantation-a-morbid-procedure-which-does-not-adversely-impact-long-term-survival
#10
Nicolas Golse, Kayvan Mohkam, Agnès Rode, Pierre Pradat, Christian Ducerf, Jean-Yves Mabrut
BACKGROUND: Indications for splenectomy (SP) during whole liver transplantation (LT) remain controversial and SP is often avoided because of common complications. We aimed to evaluate specific complications of these combined procedures. METHODS: Data were retrospectively analysed. Splenectomy was performed in patients with splenorenal shunt and/or splenic artery aneurysms or hypersplenism. Patients undergoing simultaneous transplantation and splenectomy (LTSP group) were matched to a non-splenectomy group (LT group)...
February 20, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28233672/validation-of-fistula-risk-score-calculator-in-diverse-north-american-hpb-practices
#11
Jan Grendar, Zeljka Jutric, Julie N Leal, Chad G Ball, Kimberly Bertens, Elijah Dixon, Chet W Hammill, Zachary Kastenberg, Pippa H Newell, Flavio Rocha, Brendan Visser, Ronald F Wolf, Paul D Hansen
BACKGROUND: Fistula Risk Score (FRS) is a previously developed tool to assess the risk of clinically relevant postoperative pancreatic fistula (CR-POPF) following pancreatoduodenectomy (PD). METHODS: Prospectively collected databases from 4 university affiliated and non-affiliated HPB centers in United States and Canada were used. The influence of individual baseline characteristics, FRS and FRS group on CR-POPF was assessed in univariate and multivariate analyses...
February 20, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28254159/surveillance-strategy-for-small-asymptomatic-non-functional-pancreatic-neuroendocrine-tumors-a-systematic-review-and-meta-analysis
#12
REVIEW
Ville Sallinen, Tessa Y S Le Large, Shamil Galeev, Zahar Kovalenko, Elke Tieftrunk, Raphael Araujo, Güralp O Ceyhan, Sebastien Gaujoux
BACKGROUND: Non-functional pancreatic neuroendocrine tumors (NF-PNET) are rare neoplasms being increasingly diagnosed. Surgical treatment or expectant management are both suggested for small NF-PNETs. The aim of this study was to evaluate the outcome of surveillance strategy for small NF-PNETs. METHODS: A systematic search was performed up to March 2016 in MEDLINE, EMBASE and the Cochrane Library according to the PRISMA guidelines. Data was pooled using the random-effects model...
February 18, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28223043/socio-economic-status-influences-the-likelihood-of-undergoing-surgical-treatment-for-pancreatic-cancer-in-the-netherlands
#13
Maikel J A M Bakens, Valery E P P Lemmens, Ignace H J T de Hingh
Surgical resection offers the only prospect of cure in pancreatic cancer patients. The probability of undergoing surgery is determined by several factors. The influence of socio-economic status (SES) on surgical treatment and survival was investigated in the Netherlands, a country with a widely accessible healthcare system. METHODS: Data on all patients with non-metastasised pancreatic cancer between 2005-2013 were analysed in the Eindhoven Cancer Registry (ECR). SES was categorized as low, intermediate or high...
February 17, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28223042/mixed-hepatocellular-and-cholangiocarcinoma-the-difficulty-of-finding-the-right-answer
#14
LETTER
Mikel Gastaca, Gonzalo Sapisochin
No abstract text is available yet for this article.
February 17, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28223041/is-routine-hepaticojejunostomy-at-the-time-of-unplanned-surgical-bypass-required-in-the-era-of-self-expanding-metal-stents
#15
Roberta Angelico, Shakeeb Khan, Bobby Dasari, Ravi Marudanayagam, Robert P Sutcliffe, Paolo Muiesan, John Isaac, Darius Mirza, Keith J Roberts
BACKGROUND: Hepaticojejunostomy is routinely performed in patients when inoperable disease is found at planned pancreatoduodenectomy; however, in the presence of self-expanding metal stent (SEMS) hepaticojejunostomy may not be required. The aim of this study was to assess biliary complications and outcomes in patients with unresectable disease at time of planned pancreaticoduodenectomy stratified by the management of the biliary tract. MATERIAL AND METHODS: Retrospective analysis of patients undergoing surgery in January 2010-December 2015...
February 17, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28215904/worldwide-survey-on-opinions-and-use-of-minimally-invasive-pancreatic-resection
#16
Jony van Hilst, Thijs de Rooij, Mohammed Abu Hilal, Horacio J Asbun, Jeffrey Barkun, Uggo Boggi, Olivier R Busch, Kevin C P Conlon, Marcel G Dijkgraaf, Ho-Seong Han, Paul D Hansen, Michael L Kendrick, Andre L Montagnini, Chinnusamy Palanivelu, Bård I Røsok, Shailesh V Shrikhande, Go Wakabayashi, Herbert J Zeh, Charles M Vollmer, David A Kooby, Marc G H Besselink
BACKGROUND: The introduction of minimally invasive pancreatic resection (MIPR) into surgical practice has been slow. The worldwide utilization of MIPR and attitude towards future perspectives of MIPR remains unknown. METHODS: An anonymous survey on MIPR was sent to the members of six international associations of Hepato-Pancreato-Biliary (HPB) surgery. RESULTS: The survey was completed by 435 surgeons from 50 countries, with each surgeon performing a median of 22 (IQR 12-40) pancreatic resections annually...
February 16, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28215903/minimally-invasive-distal-pancreatectomy
#17
REVIEW
Bård I Røsok, Thijs de Rooij, Jony van Hilst, Markus K Diener, Peter J Allen, Charles M Vollmer, David A Kooby, Shailesh V Shrikhande
BACKGROUND: The first International conference on Minimally Invasive Pancreas Resection was arranged in conjunction with the annual meeting of the International Hepato-Pancreato-Biliary Association (IHPBA), in Sao Paulo, Brazil on April 19th 2016. The presented evidence and outcomes resulting from the session for minimally invasive distal pancreatectomy (MIDP) is summarized and addressed perioperative outcome, the outcome for cancer and patient selection for the procedure. METHODS: A literature search was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to compare MIDP and open distal pancreatectomy...
February 16, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28215513/combined-hepatectomy-and-hepatic-pedicle-lymphadenectomy-in-colorectal-liver-metastases-is-justified
#18
Russell Hodgson, Harsheet Sethi, Andrew H Ling, Peter Lodge
BACKGROUND: The aim of this study was to describe the outcome of patients with colorectal liver metastases (CRLM) and radiological or clinical evidence of metastatic hepatic lymph node involvement who underwent combined hepatectomy and hepatic pedicle lymphadenectomy. METHODS: Retrospective analysis of a prospectively maintained audit of 2082 patients undergoing liver resection for CRLM between 1994 and 2014. Age, type of resection, CT/MRI/PET detection, location, disease recurrence and survival were analysed...
February 15, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28202218/pancreatic-fistula-risk-for-pancreatoduodenectomy-an-international-survey-of-surgeon-perception
#19
Matthew T McMillan, Giuseppe Malleo, Claudio Bassi, Michael H Sprys, Brett L Ecker, Jeffrey A Drebin, Charles M Vollmer
INTRODUCTION: Clinically relevant postoperative pancreatic fistula (CR-POPF) is a morbid complication following pancreatoduodenectomy (PD). It is unclear how pancreatic surgeons perceive risk for this complication, and the implications thereof. METHODS: A web-based survey was distributed to members of 22 international GI surgical societies. CR-POPF risk factors were categorized as follows: (i) patient factors, (ii) pancreatic gland characteristics, (iii) intraoperative variables, (iv) perioperative mitigation techniques, or (v) institutional features...
February 12, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28190710/neutrophil-to-lymphocyte-ratio-predicts-disease-progression-following-intra-arterial-therapy-of-hepatocellular-carcinoma
#20
Matthew D Taussig, Mary Ellen Irene Koran, Samdeep K Mouli, Asma Ahmad, Sunil Geevarghese, Jennifer C Baker, Andrew J Lipnik, Fil Banovac, Daniel B Brown
BACKGROUND: Prospectively predicting response to intra-arterial therapy for hepatocellular carcinoma (HCC) is challenging. Neutrophil/lymphocyte ratio (NLR) is a serum biomarker that is associated with survival for multiple malignancies. It was hypothesized that increased NLR would be associated with early disease progression after intra-arterial therapy of HCC. METHODS: The outcomes of 86 treatment-naïve patients who had chemoembolization or radioembolization of HCC between July 2013-July 2014 were reviewed...
February 9, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
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