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HPB: the Official Journal of the International Hepato Pancreato Biliary Association

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https://www.readbyqxmd.com/read/29146469/percutaneous-transcystic-balloon-dilation-for-common-bile-duct-stone-removal-in-high-surgical-risk-patients-with-acute-cholecystitis-and-co-existing-choledocholithiasis
#1
Wujie Wang, Changjun Wang, Hongjun Qi, Yongzheng Wang, Yuliang Li
BACKGROUND: Percutaneous procedures to treat common bile duct (CBD) stones typically require access via intrahepatic bile ducts. This study aimed to describe the outcomes of a percutaneous transcystic approach that expelled the CBD stones into the duodenum after percutaneous transcystic balloon dilation of the ampulla (PTCBDA) for high-risk patients who present with acute cholecystitis and CBD stones. METHODS: Patients diagnosed with acute cholecystitis and CBD stones who were deemed too high-risk for surgery or general anesthesia and were treated with PTCBDA and CBD stone removal between March 2010 and November 2015 were included for further analysis...
November 13, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29129486/a-nationwide-analysis-of-re-exploration-after-liver-transplant
#2
Zhobin Moghadamyeghaneh, Mahmoud Alameddine, Joshua S Jue, Giselle Guerra, Gennaro Selvaggi, Seigo Nishida, J Fan, Thiago Beduschi, Rodrigo Vianna
BACKGROUND: A retrospective review to investigate rate and outcomes of re-exploration following liver transplantation in the United States. METHODS: The NIS database was used to examine outcomes of patients who underwent re-exploration following liver transplantation from 2002 to 2012. Multivariate regression analysis was performed to compare outcomes of patients with and without reoperation. RESULTS: We sampled a total of 12,075 patients who underwent liver transplantation...
November 9, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29103839/can-echogenic-appearance-of-neuroendocrine-liver-metastases-on-intraoperative-ultrasonography-predict-tumor-biology-and-prognosis
#3
Epameinondas Dogeas, Charing C N Chong, Matthew J Weiss, Nita Ahuja, Michael A Choti
BACKGROUND: Determining the biologic behavior of neuroendocrine liver metastases (NELM) is important when managing patients with this disease. We sought to define the intraoperative ultrasound (IOUS) characteristics of NELM and correlate with tumor biology and prognosis. METHODS: Prospective data on patients who underwent IOUS and surgical intervention for NELM were collected, with images digitally recorded, blindly reviewed, and scored for echogenicity. Association between sonographic appearance, clinicopathologic factors and long-term outcomes was analyzed...
November 2, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29100711/a-predictive-nomogram-to-identify-factors-influencing-the-success-of-a-concomitant-laparoscopic-cholecystectomy-with-common-bile-duct-exploration-for-choledocholithiasis
#4
Koy Min Chue, Jun Wei Bryan Aw, Sin Hui Melissa Chua, Zhaojin Chen, Shridhar Ganpathi Iyer, Krishnakumar Madhavan, Alfred Wei Chieh Kow
BACKGROUND: Single-staged laparoscopic common bile duct exploration (LCBDE) offers clear benefits in terms of cost and shorter hospitalization stays. However, a failed LCBDE requiring conversion to open surgery is associated with increased morbidity. This study reviewed the factors determining success of LCBDE, and created a predictive nomogram to stratify patients for the procedure. METHODS: A retrospective analysis of 109 patients who underwent LCBDE was performed...
October 31, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29092792/long-term-health-related-quality-of-life-after-pancreatic-resection-for-malignancy-in-patients-with-and-without-severe-postoperative-complications
#5
Hanne D Heerkens, Lisanne van Berkel, Dorine S J Tseng, Evelyn M Monninkhof, Hjalmar C van Santvoort, Jeroen Hagendoorn, Inne H M Borel Rinkes, Irene M Lips, Martijn Intven, I Quintus Molenaar
BACKGROUND: Surgery for pancreatic cancer yields significant morbidity and mortality risks and survival is limited. Therefore, the influence of complications on quality of life (QoL) after pancreatic surgery is important. This study compares QoL in patients with and without severe complications after surgery for pancreatic (pre-)malignancy. METHODS: This prospective cohort study scored complications after pancreatic surgery according to the Clavien-Dindo system and the definitions of the International Study Group of Pancreatic Surgery...
October 29, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29110990/transjugular-intrahepatic-portosystemic-shunt-as-a-bridge-to-non-hepatic-surgery-in-cirrhotic-patients-with-severe-portal-hypertension-a-systematic-review
#6
REVIEW
Eylon Lahat, Chetana Lim, Prashant Bhangui, Liliana Fuentes, Michael Osseis, Toufic Moussallem, Chady Salloum, Daniel Azoulay
BACKGROUND: Portal hypertension (PHTN) increases the risk of non-hepatic surgery in cirrhotic patients. This first systematic review analyzes the place of transjugular intrahepatic portosystemic shunt (TIPS) in preparation for non-hepatic surgery in such patients. METHODS: Medline, EMBASE, and Scopus databases were searched from 1990 to 2017 to identify reports on outcomes of non-hepatic surgery in cirrhotic patients with PHTN prepared by TIPS. Feasibility of TIPS and the planned surgery, and the short- and long-term outcomes of the latter were assessed...
October 27, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29107445/-apple-far-from-the-tree-comparative-effectiveness-of-fiberoptic-single-operator-cholangiopancreatoscopy-fsocp-and-digital-socp-dsocp
#7
Meir Mizrahi, Tawfik Khoury, Yan Wang, Jonah Cohen, Jennifer Sheridan, Ram Chuttani, Tyler M Berzin, Mandeep S Sawhney, Douglas K Pleskow
BACKGROUND: While the fiberoptic single-operator cholangiopancreatoscopy (FSOCP) system has demonstrated efficacy in the diagnosis and management of pancreaticobiliary diseases, the digital SOCP (DSOCP) appears to provide higher resolution digital imaging, however a comparison of these devices has not been established. The aim of this work was to compare the efficacy of FSOCP and DSOCP in biliary stone disease and indeterminate biliary strictures. METHODS: A retrospective analysis of a prospective cohort was performed in patients undergoing FSOCP or DSOCP demographics included indication, diagnostic yield, procedure time, radiation dose, and complications...
October 26, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29046260/assessment-of-liver-regeneration-after-associating-liver-partition-and-portal-vein-ligation-for-staged-hepatectomy-a-comparative-study-with-portal-vein-ligation
#8
Ruo-Fan Sheng, Li Yang, Kai-Pu Jin, He-Qing Wang, Hao Liu, Yuan Ji, Cai-Xia Fu, Meng-Su Zeng
BACKGROUND: To investigate the diagnostic value of diffusion kurtosis imaging (DKI) and diffusion-weighted imaging (DWI) in assessing liver regeneration after associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) compared with portal vein ligation (PVL). METHODS: Thirty rats were divided into the ALPPS, PVL, and control groups. DKI and DWI were performed before and 7 days after surgery. Corrected apparent diffusion (D), kurtosis (K) and apparent diffusion coefficient (ADC) were calculated and compared, radiologic-pathologic correlations were evaluated...
October 15, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29029986/radiofrequency-ablation-for-colorectal-cancer-liver-metastases-initially-greater-than-25%C3%A2-mm-but-downsized-by-neo-adjuvant-chemotherapy-is-associated-with-increased-rate-of-local-tumor-progression
#9
Léonor Benhaim, Mostafa El Hajjam, Robert Malafosse, Jacques Sellier, Catherine Julie, Alain Beauchet, Bernard Nordlinger, Frédérique Peschaud
BACKGROUND: Radiofrequency ablation (RFA) is a valid treatment for liver metastases from colorectal cancer (CRLM) smaller than 25 mm and unsuitable for surgical resection. Tumor size is predictive for local tumor progression (LTP). The aim of this study was to evaluate whether RFA is indicated for lesions >25 mm at presentation but <25 mm after chemotherapy. METHOD: Patients who underwent RFA for CRLM after chemotherapy (January 2004-December 2012) were reviewed...
October 10, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29029985/clinical-and-pathological-outcomes-after-irreversible-electroporation-of-the-pancreas-using-two-parallel-plate-electrodes-a-porcine-model
#10
Steffi J E Rombouts, Willemijn P M van Dijck, Maarten W Nijkamp, Tyche C Derksen, Lodewijk A A Brosens, Frederik J H Hoogwater, Maarten S van Leeuwen, Inne H M Borel Rinkes, Richard van Hillegersberg, Fred H Wittkampf, Izaak Q Molenaar
BACKGROUND: Irreversible electroporation (IRE) by inserting needles around the tumor as treatment for locally advanced pancreatic cancer entails several disadvantages, such as incomplete ablation due to field inhomogeneity, technical difficulties in needle placement and a risk of pancreatic fistula development. This experimental study evaluates outcomes of IRE using paddles in a porcine model. METHODS: Six healthy pigs underwent laparotomy and were treated with 2 separate ablations (in head and tail of the pancreas)...
October 10, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29033025/the-clinical-utility-of-immunoglobulin-g4-in-the-evaluation-of-autoimmune-pancreatitis-and-pancreatic-adenocarcinoma
#11
Linda M Pak, Mark A Schattner, Vinod Balachandran, Michael I D'Angelica, Ronald P DeMatteo, T Peter Kingham, William R Jarnagin, Peter J Allen
BACKGROUND: Elevation in the serum immunoglobulin-G4 (IgG4) level has been used as a diagnostic marker to distinguish autoimmune pancreatitis (AIP) from pancreatic ductal adenocarcinoma (PDAC), but its true utility is ill-defined. This study evaluates the clinical utility of IgG4 in differentiating AIP from PDAC. METHODS: All patients evaluated in the hepatopancreaticobiliary surgery clinics with measured serum IgG4 were included. Patients were divided into normal IgG4 (<135 mg/dL) and elevated IgG4 (≥135 mg/dL) groups...
October 9, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28993044/risk-factors-for-early-readmission-after-total-pancreatectomy-and-islet-auto-transplantation
#12
Rauf Shahbazov, Bashoo Naziruddin, Kunal Yadav, Giovanna Saracino, Gumpei Yoshimatsu, Mazhar A Kanak, Ernest Beecherl, Peter T Kim, Marlon F Levy
BACKGROUND: Little published data exist examining causes of hospital readmission following total pancreatectomy with islet autotransplantation (TPIAT). METHODS: A retrospective analysis was performed of a prospectively collected institutional TPIAT database. Primary outcome was unplanned readmission to the hospital within 30 days from discharge. Reasons and risk factors for readmission as well as islet function were evaluated and compared by univariate and multivariate analysis...
October 6, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28988913/surgical-treatment-strategy-for-hepatocellular-carcinoma-in-patients-with-impaired-liver-function-hepatic-resection-or-radiofrequency-ablation
#13
Takanobu Yamao, Katsunori Imai, Yo-Ichi Yamashita, Takayoshi Kaida, Shigeki Nakagawa, Kosuke Mima, Daisuke Hashimoto, Akira Chikamoto, Takatoshi Ishiko, Hideo Baba
BACKGROUND: To compare the survival impacts of radiofrequency ablation (RFA) as an initial treatment for hepatocellular carcinoma (HCC) in patients with impaired liver functional reserve compared to those of hepatic resection (HR). METHODS: In total, 104 patients with liver damage B as defined by the Liver Cancer Study Group of Japan underwent RFA (n = 33) or HR (n = 71) as an initial treatment for hepatocellular carcinoma. The overall survival (OS) and disease-free survival (DFS) rates were compared, and independent prognostic factors were identified...
October 5, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28988702/prognosis-of-sporadic-resected-small-%C3%A2-2%C3%A2-cm-nonfunctional-pancreatic-neuroendocrine-tumors-a-multi-institutional-study
#14
Ville J Sallinen, Tessa T Y Le Large, Elke Tieftrunk, Shamil Galeev, Zahar Kovalenko, Sven-Petter Haugvik, Anne Antila, Oskar Franklin, Emma Martinez-Moneo, Stuart M Robinson, Francesco Panzuto, Nicolas Regenet, Francesca Muffatti, Stefano Partelli, Dominik Wiese, Philippe Ruszniewski, Bertrand Dousset, Bjørn Edwin, Detlef K Bartsch, Alain Sauvanet, Falconi Massimo, Güralp O Ceyhan, Sebastien Gaujoux
BACKGROUND: Malignant potential of small (≤20 mm) nonfunctional pancreatic neuroendocrine tumors (sNF-PNET) is difficult to predict and management remain controversial. The aim of this study was to assess the prognosis of sporadic nonmetastatic sNF-PNETs. METHODS: Patients were identified from databases of 16 centers. Outcomes and risk factors for recurrence were identified by uni- and multivariate analyses. RESULTS: sNF-PNET was resected in 210 patients, and 66% (n = 138) were asymptomatic...
October 5, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28988703/cost-of-achieving-equivalent-outcomes-in-sicker-patients-after-liver-transplant
#15
Vikrom K Dhar, Koffi Wima, Young Kim, Richard S Hoehn, Andrew D Jung, Audrey E Ertel, Tayyab S Diwan, Flavio Paterno, Shimul A Shah
BACKGROUND: We aimed to characterize variability in cost after straightforward orthotopic liver transplant (OLT). METHODS: Using the University HealthSystem Consortium and Scientific Registry of Transplant Recipients databases, we identified patients who underwent OLT between 2011 and 2014. Patients meeting criteria for straightforward OLT, defined as length of stay < 14 days with discharge to home, were selected (n = 5763) and grouped into tertiles (low, medium, high) according to cost of perioperative stay...
October 4, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28978403/completion-pancreatectomy-in-the-acute-management-of-pancreatic-fistula-after-pancreaticoduodenectomy-a-systematic-review-and-qualitative-synthesis-of-the-literature
#16
REVIEW
Alexsander K Bressan, Michael Wahba, Elijah Dixon, Chad G Ball
BACKGROUND: Pancreatic fistula remains a major complication after pancreaticoduodenectomy (PD). Re-operation is generally considered only after exhaustion of non-surgical options. A variety of pancreas-preserving operations have been proposed, but completion pancreatectomy (CP) stands out in locally complicated cases as a universal approach. This study aims to provide a qualitative synthesis of the peer-reviewed literature regarding emergency CP for post-PD pancreatic fistula. METHODS: A systematic search of PubMed and EMBASE for all studies reporting clinical outcomes for CP in the acute treatment of pancreatic fistula following PD from January 1975 until May 2016...
October 1, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28969960/are-the-current-difficulty-scores-for-laparoscopic-liver-surgery-telling-the-whole-story-an-international-survey-and-recommendations-for-the-future
#17
Mark C Halls, Daniel Cherqui, Mark A Taylor, John N Primrose, Mohammed Abu Hilal
BACKGROUND: Recent studies have suggested that the difficulty of laparoscopic liver resections are related to both patient and tumour factors, however the available difficulty scoring systems only incorporate tumour factors. The aim of this study was to assess the opinion of laparoscopic liver surgeons regarding the factors that affect the perceived difficulty of laparoscopic liver resections. METHOD: Using a Visual Analogue Scale an international survey of laparoscopic liver surgeons was undertaken to assess the perceived difficulty of 26 factors previously demonstrated to affect the difficulty of a laparoscopic liver resection...
September 29, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28969959/impact-of-chemotherapy-associated-liver-injury-on-tumour-regression-grade-and-survival-in-patients-with-colorectal-liver-metastases
#18
Junfang Zhao, Pamir Sawo, Sander S Rensen, Margriet M J Rouflart, Alison Winstanley, Celien P H Vreuls, Joanne Verheij, Kim M C van Mierlo, Toine M Lodewick, Victor van Woerden, Frank H van Tiel, Ronald M van Dam, Cornelis H C Dejong, Steven W M Olde Damink
BACKGROUND: An inverse relation between chemotherapy-associated liver injury (CALI) and tumour response to chemotherapy has been reported. The aim was to validate these findings, and further investigate the impact of CALI on survival in patients who underwent partial hepatectomy for colorectal liver metastases (CRLM). METHODS: Patients who received neoadjuvant chemotherapy and underwent partial hepatectomy for CRLM between 2008 and 2014 were included. Liver and tumour specimens were histologically examined for CALI (steatosis, steatohepatitis, sinusoidal dilatation [SD], nodular regeneration) and tumour regression grade (TRG)...
September 29, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28966032/how-to-choose-and-compare-between-radiofrequency-ablation-and-transarterial-chemoembolization-for-recurrent-hepatocellular-carcinoma
#19
LETTER
Zheng Wang, Li-Yang Sun, Hao Xing, Han Zhang, Tian Yang
No abstract text is available yet for this article.
September 28, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28966031/multicenter-outcomes-of-robotic-reconstruction-during-the-early-learning-curve-for-minimally-invasive-pancreaticoduodenectomy
#20
Ammara A Watkins, Tara S Kent, William E Gooding, Ugo Boggi, Sri Chalikonda, Michael L Kendrick, R Matthew Walsh, Herbert J Zeh, A James Moser
BACKGROUND: Perceived excess morbidity during the early learning curve of minimally-invasive pancreaticoduodenectomy (MIPD) has limited widespread adoption. It was hypothesized that robot-assisted reconstruction (RA) after MIPD allows anastomotic outcomes equivalent to open pancreaticoduodenectomy (PD). METHODS: Intent to treat analysis of centrally audited data accrued during early adoption of RA-MIPD at five centers. RESULTS: CUSUM analysis of operating times at each center identified 92 RA-MIPD during the early learning curve...
September 28, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
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