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HPB: the Official Journal of the International Hepato Pancreato Biliary Association

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https://www.readbyqxmd.com/read/30030081/modification-and-establishment-of-ct-criteria-in-preoperative-assessment-of-portal-venous-invasion-by-hilar-cholangiocarcinoma
#1
Qun Zhou, Yue Guan, Liang Mao, Yong Zhu, Jun Chen, Jiong Shi, Min Tang, Yudong Qiu, Bin Zhu, Jian He
BACKGROUND: To compare the diagnostic performance of CT criteria and to establish a new model in evaluating portal venous invasion by hilar cholangiocarcinoma. METHODS: CT images of 67 patients with hilar cholangiocarcinoma were retrospectively reviewed. Modified Loyer's, Lu's and Li's standard introduced from pancreatic cancer were used to evaluate portal venous invasion with the reference of intraoperative findings and/or postoperative pathological diagnosis. A new model was constructed with modified Lu's standard and contact length between portal vein and tumor...
July 17, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/30017784/recurrent-pyogenic-cholangitis-an-independent-poor-prognostic-indicator-for-resectable-intrahepatic-cholangiocarcinoma-a-propensity-score-matched-analysis
#2
Ka W Ma, Tan T Cheung, Wong H She, Kenneth S H Chok, Albert C Yan Chan, Jeff W Chiu Dai, Chung M Lo
BACKGROUND: Recurrent pyogenic cholangitis (RPC) is a known risk factor for intrahepatic cholangiocarcinoma (ICC), whether it represents a poor prognostic factor remains controversial. The aim of this study was to investigate the post-hepatectomy oncological outcomes of patients with ICC and coexisting RPC. METHOD: A retrospective analysis with propensity score matching (PSM) was performed for comparison between ICC patient with and without RPC. RESULTS: There were 143 patients with ICC with a median follow-up of 21 months...
July 13, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/30017783/alpha-fetoprotein-response-following-transarterial-chemoembolization-indicates-improved-survival-for-intermediate-stage-hepatocellular-carcinoma
#3
Guanghua Liu, Qiang Ouyang, Fang Xia, Guoping Fan, Juming Yu, Caiyuan Zhang, Dengbin Wang
BACKGROUND: To investigate the clinical value of the alpha-fetoprotein (AFP) response following transcatheter arterial chemoembolization (TACE) in intermediate-stage hepatocellular carcinoma (HCC). METHODS: Data on patients with Barcelona Clinic Liver Cancer B staging system were analyzed. An AFP response was defined as a decrease in AFP of more than 20% after a TACE session. The association between AFP response and treatment outcome regarding imaging response and overall survival (OS) was explored...
July 13, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/30007534/parenchyma-sparing-liver-resection-for-hepatocellular-carcinoma-in-left-lateral-section-is-associated-with-better-liver-volume-recovery
#4
Kosuke Kobayashi, Yoshikuni Kawaguchi, Junichi Arita, Nobuhisa Akamatsu, Junichi Kaneko, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo
BACKGROUND: Left lateral sectionectomy (LLS) is frequently performed for surgical treatment of hepatocellular carcinoma (HCC) located in the left lateral section. However, no reports have described liver resection for such HCCs using a parenchyma-sparing strategy involving anatomic resection (AR) of segment II (S2 AR) or segment III (S3 AR). METHODS: From 1994 to 2014, patients who underwent LLS and S2 AR or S3 AR for HCC were included in the analysis. Short- and long-term outcomes and pre- and postoperative LV were assessed...
July 11, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/30005994/clinical-update-on-management-of-pancreatic-trauma
#5
REVIEW
Kjetil Søreide, Thomas G Weiser, Rowan W Parks
BACKGROUND: Pancreatic injury is rare and optimal diagnosis and management is still debated. The aim of this study was to review the existing data and consensus on management of pancreatic trauma. METHODS: Systematic literature review until May 2018. RESULTS: Pancreas injury is reported in 0.2-0.3% of all trauma patients. Severity is scored by the organ injury scale (OIS), with new scores including physiology needing validation. Diagnosis is difficult, clinical signs subtle, and imaging by ultrasound (US) and computed tomography (CT) non-specific with <60% sensitivity for pancreatic duct injury...
July 11, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/30005993/minimally-invasive-management-of-the-entire-treatment-sequence-in-patients-with-stage-iv-colorectal-cancer-a-propensity-score-weighting-analysis
#6
Claire Goumard, Y Nancy You, Masayuki Okuno, Onur Kutlu, Hsiang-Chun Chen, Eve Simoneau, Eduardo A Vega, Yun-Shin Chun, C David Tzeng, Cathy Eng, Jean-Nicolas Vauthey, Claudius Conrad
BACKGROUND: In patients with stage IV colorectal cancer (CRC), minimally invasive surgery (MIS) may offer optimal oncologic outcome with low morbidity. However, the relative benefit of MIS compared to open surgery in patients requiring multistage resections has not been evaluated. METHODS: Patients who underwent totally minimally invasive (TMI) or totally open (TO) resections of CRC primary and liver metastases (CLM) in 2009-2016 were analyzed. Inverse probability of weighted adjustment by propensity score was performed before analyzing risk factors for complications and survival...
July 10, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/30005992/preoperative-risk-analysis-index-for-frailty-predicts-short-term-outcomes-after-hepatopancreatobiliary-surgery
#7
Dirk J van der Windt, Patrick Bou-Samra, Esmaeel R Dadashzadeh, Xilin Chen, Patrick R Varley, Allan Tsung
BACKGROUND: The Risk Analysis Index (RAI) for frailty is a rapid survey for comorbidities and performance status, which predicts mortality after general surgery. We aimed to validate the RAI in predicting outcomes after hepatopancreatobiliary surgery. METHODS: Associations of RAI, determined in 162 patients prior to undergoing hepatopancreatobiliary surgery, with prospectively collected 30-day post-operative outcomes were analyzed with multivariate logistic and linear regression...
July 10, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29958811/long-term-outcomes-of-patients-with-intraductal-growth-sub-type-of-intrahepatic-cholangiocarcinoma
#8
Fabio Bagante, Matthew Weiss, Sorin Alexandrescu, Hugo P Marques, Luca Aldrighetti, Shishir K Maithel, Carlo Pulitano, Todd W Bauer, Feng Shen, George A Poultsides, Olivier Soubrane, Guillaume Martel, Bas G Koerkamp, Alfredo Guglielmi, Endo Itaru, Timothy M Pawlik
BACKGROUND: Intraductal-growth (IG) type of intrahepatic cholangiocarcinoma (ICC) may be associated with a favorable prognosis compared with mass-forming (MF) and periductal-infiltrating (PI) ICC. METHODS: The clinico-pathological characteristics and long-term outcomes of 1206 patients undergoing liver resection for ICC were compared based on the ICC morphological classification. RESULTS: Compared with MF patients, IG patients had a higher incidence of poor/un-differentiated tumor, lympho-vascular, and perineural invasion (poor/un-differentiated: MF, 18% vs...
June 26, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29958810/explant-portal-vein-for-reconstructing-middle-hepatic-vein-in-right-lobe-living-donor-liver-transplantation-outcome-analysis
#9
Deeplaxmi Purushottam Borle, Viniyendra Pamecha, Kishore Gurumoorthy Subramanya Bharathy, Shridhar Vasantrao Sasturkar, Piyush Kumar Sinha, Yashwant Patidar, Binit Sureka, Shalini Thapar Laroia
BACKGROUND: The aim of the study was to study the four week patency rates of the reconstructed neo middle hepatic vein specifically using the explant portal vein (PV) in right hemiliver live donor liver transplantation (LDLT). We hypothesized that short term patency of the neo-MHV should result in good graft and patient outcomes. METHODS: Pre, intra and post operative variables were prospectively collected for 88 consecutive patients undergoing right hemiliver LDLT from January 2014 to October 2015...
June 26, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29945845/clinical-impact-of-the-updated-international-postoperative-pancreatic-fistula-definition-in-distal-pancreatectomy
#10
Jony van Hilst, Matteo de Pastena, Thijs de Rooij, Adnan Alseidi, Olivier R Busch, Susan van Dieren, Casper H van Eijck, Francesco Giovinazzo, Bas Groot Koerkamp, Giovanni Marchegiani, G Ryne Marshall, Mohammed Abu Hilal, Claudio Bassi, Marc G Besselink
BACKGROUND: Postoperative pancreatic fistula (POPF) remains the most common complication after distal pancreatectomy. The International Study Group on Pancreatic Surgery definition of POPF is used worldwide. Recently, an update of the definition was published. The aim of this study was to determine the clinical impact of the update. METHODS: An international retrospective validation study, including patients who underwent DP (2005 -2016) in 5 centers was performed...
June 23, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29941288/surgical-technique-and-results-of-intrapancreatic-bile-duct-resection-for-hilar-malignancy-with-video
#11
Takehiro Noji, Keisuke Okamura, Kimitaka Tanaka, Yoshitsugu Nakanishi, Toshimichi Asano, Toru Nakamura, Takahiro Tsuchikawa, Satoshi Hirano
BACKGROUND: Hilar malignancy can occasionally be associated with high grade dysplasia (HGD) adjacent to invasive malignancy. For patients with HGD extending into the intrapancreatic bile duct, the authors adopted intrapancreatic bile duct resection (IP-BDR). The aims of this study were to compare the incidence of clinically relevant postoperative pancreatic fistula (CR-POPF), distal R0 resection and local recurrence within the distal bile duct remnant for patients undergoing extrahepatic bile duct resection without pancreaticoduodenectomy (with or without IP-BDR)...
June 23, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29941289/management-of-postoperative-pancreatic-fistula-after-pancreatoduodenectomy-high-mortality-after-completion-pancreatectomy-reply-to-bressan-et-al-completion-pancreatectomy-in-the-acute-management-of-pancreatic-fistula-after-pancreaticoduodenectomy
#12
LETTER
F Jasmijn Smits, I Quintus Molenaar, Marc G Besselink, Olivier R Busch, Casper H van Eijck, Hjalmar C van Santvoort
No abstract text is available yet for this article.
June 22, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29937419/waitlist-mortality-and-post-transplant-survival-in-patients-with-cholestatic-liver-disease-impact-of-changes-in-allocation-policy
#13
Katharina Staufer, Danijel Kivaranovic, Susanne Rasoul-Rockenschaub, Thomas Soliman, Michael Trauner, Gabriela Berlakovich
BACKGROUND: This study investigated the impact of Model of end-stage liver disease (MELD)-score introduction (MELDi) on waitlist mortality and post-liver transplant (LT) survival in primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). METHODS: LT candidates with PSC or PBC listed between January 1983 and March 2016 were included and followed until December 2016. After MELDi in 2004, PBC patients were listed according to labMELD, PSC patients according to the highest MELD during active cholangitis (chMELD)...
June 21, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29929786/definition-of-an-extended-minimum-level-of-lymphadenectomy-in-non-pancreatic-periampullary-cancer-resections
#14
Bing Liu, Max Heckler, Ulrike Heger, Susanne Roth, Ulla Klaiber, Markus W Büchler, Oliver Strobel, Christoph W Michalski, Thilo Hackert
BACKGROUND: The number of lymph nodes to be resected in surgery for non-pancreatic periampullary cancer remains unclear. METHODS: The Surveillance, Epidemiology, and End Results (SEER) database was used to gather information from a large retrospective cohort. To define a novel, reasonable cut-off associated with survival, we stratified patients into subgroups depending on the number of resected lymph nodes. RESULTS: 1481 nodal-negative patients resected for periampullary cancer (excluding pancreatic ductal adenocarcinoma) were included...
June 19, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29929784/a-preoperative-nomogram-predicts-prognosis-of-up-front-resectable-patients-with-pancreatic-head-cancer-and-suspected-venous-invasion
#15
Yi-Nan Shen, Xue-Li Bai, Gang Jin, Qi Zhang, Jun-Hua Lu, Ren-Yi Qin, Ri-Sheng Yu, Yao Pan, Ying Chen, Pei-Wei Sun, Cheng-Xiang Guo, Xiang Li, Tao Ma, Guo-Gang Li, Shun-Liang Gao, Jian-Ying Lou, Ri-Sheng Que, Wan Y Lau, Ting-Bo Liang
BACKGROUND: Pancreatic head adenocarcinoma is commonly diagnosed at an advanced stage when adjacent vascular invasion is present. This study aimed to establish a preoperative prognostic nomogram for patients who underwent attempted curative resectional surgery for pancreatic head cancer with suspected peripancreatic venous invasion. METHODS: Data on all consecutive patients were retrospectively collected from 2012 to 2016 at four academic institutions. The demographic and radiological parameters were analyzed using univariate and multivariate Cox regression analyses...
June 19, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29929785/a-comparison-of-microwave-thermosphere-versus-radiofrequency-thermal-ablation-in-the-treatment-of-colorectal-liver-metastases
#16
Hideo Takahashi, Bora Kahramangil, Emin Kose, Eren Berber
BACKGROUND: Microwave thermosphere ablation (MTA) is a new generation technology. The aim of this study was to compare the efficacy of MTA and radiofrequency ablation (RFA) in achieving local tumor control in patients with colorectal liver metastasis (CRLM). METHODS: This was a retrospective study of a prospective ablation database. Fifty-four patients with 155 CRLM lesions underwent RFA and 51 patients with 121 lesions underwent MTA. Patients were managed by a multidisciplinary team...
June 18, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29895441/ninety-day-mortality-following-pancreatoduodenectomy-in-england-has-the-optimum-centre-volume-been-identified
#17
Z Liu, I S Peneva, F Evison, S Sahdra, D F Mirza, R M Charnley, R Savage, P A Moss, K J Roberts
BACKGROUND: Mortality following pancreatoduodenectomy is related to centre volume although the optimal volume is not defined. METHODS: Patients undergoing PD between 2001 and 2016 were identified from UK national databases. The effects of patient variables, centre volume and time period upon 90 day mortality were studied. RESULTS: 90 day mortality (970/14,935, 6.5%) was related to advanced age, comorbidity, diagnosis, ethnicity, deprivation, centre volume and time period...
June 9, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29891423/high-rate-of-positive-lymph-nodes-in-t1a-gallbladder-cancer-does-not-translate-to-decreased-survival-a-population-based-propensity-score-adjusted-analysis
#18
Nastassja Köhn, Johannes Maubach, Rene Warschkow, Catherine Tsai, Daniel P Nussbaum, Daniel Candinas, Beat Gloor, Bruno M Schmied, Dan G Blazer, Mathias Worni
BACKGROUND: Current consensus guidelines suggest that gallbladder cancer (GBC) patients with resected T1a disease can be observed while patients with T1b or greater lesions should undergo lymphadenectomy (LNE). The primary aim of this study was to critically explore the impact of LNE in early-stage GBC on overall survival (OS) on a population-based level. METHOD: The 2004-2014 National Cancer Database was reviewed to identify non-metastatic GBC patients with T1a, T1b, or T2 disease and grouped whether a dedicated LNE was performed...
June 8, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29887263/intra-arterial-therapies-for-unresectable-and-chemorefractory-colorectal-cancer-liver-metastases-a-systematic-review-and-meta-analysis
#19
REVIEW
Jordan Levy, Jesse Zuckerman, Richard Garfinkle, Sergio A Acuna, Jacynthe Touchette, Tsafrir Vanounou, Jean-Sebastien Pelletier
BACKGROUND: A large proportion of patients with colorectal cancer liver metastases (CRCLM) not amenable to curative liver resection will progress on systemic therapy. Intra-arterial therapies (IAT) including conventional transarterial chemoembolization (cTACE), drug eluting beads (DEB-TACE) and yttrium-90 radioembolization (Y-90) are indicated to prolong survival and palliate symptoms. The purpose of this systematic review and meta-analysis is to compare the survival benefit and radiologic response of three intra-arterial therapies in patients with chemorefractory and unresectable CRCLM...
June 7, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29887262/resection-of-gallbladder-remnants-after-subtotal-cholecystectomy-presentation-and-management
#20
Seth J Concors, Matthew L Kirkland, Alan L Schuricht, Daniel T Dempsey, Jon B Morris, Charles M Vollmer, Jeffery A Drebin, Major K Lee
BACKGROUND: Subtotal cholecystectomy (SC) involves removal of a portion of the gallbladder typically due to hazardous inflammation. While this technique reliably prevents common bile duct (CBD) injury, future procedures can be required if the gallbladder remnant becomes symptomatic. The morbidity associated with resection of gallbladder remnants in patients that previously underwent SC is reviewed. METHODS: Records for patients having undergone redo cholecystectomy for symptomatic gallbladder remnants in a tertiary care system from 2013 to 2017 were retrospectively reviewed...
June 7, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
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