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HPB: the Official Journal of the International Hepato Pancreato Biliary Association

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https://www.readbyqxmd.com/read/28108099/risk-stratification-and-prognostic-nomogram-for-post-recurrence-overall-survival-in-patients-with-recurrent-extrahepatic-cholangiocarcinoma
#1
Byoung Hyuck Kim, Kyubo Kim, Eui Kyu Chie, Jeanny Kwon, Jin-Young Jang, Sun Whe Kim, Do-Youn Oh, Yung-Jue Bang
BACKGROUND: This study aimed to investigate post-recurrence overall survival (PROS) in patients with recurrent extrahepatic cholangiocarcinoma (EHC) and to indicate which groups of patients need active salvage treatments. METHODS: We retrospectively reviewed the records of 251 consecutive patients who underwent curative surgery followed by adjuvant chemoradiotherapy for EHC. Among these, 144 patients experienced a recurrence and were included for further analysis...
January 17, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28100404/gallbladder-adenomyomatosis-not-always-benign
#2
LETTER
Lindsay Howe, Gopal C Kowdley, Steven Clark Cunningham
No abstract text is available yet for this article.
January 15, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28089365/gastric-bleeding-risk-following-spleen-preserving-distal-pancreatectomy-with-excision-of-the-splenic-vessels-a%C3%A2-long-term-follow-up
#3
D Louis, A Alassiri, S Kirzin, S Blaye-Felice, M Chalret du Rieu, C H Julio, E Bloom, L Ghouti, B Pradère, G Portier, N Carrère
BACKGROUND: Spleen-preserving distal pancreatectomy with resection of the splenic vessels (VR-SPDP) is an effective procedure. However, hemodynamic changes in splenogastric circulation may lead to the development of gastric varices (GV) with a risk of gastrointestinal (GI) bleeding. This retrospective study aimed to assess the long-term postoperative clinical follow-up of patients and review the late postoperative abdominal computed tomography (CT) or endoscopic examination. METHODS: From 1988 to 2015, 48 consecutive VR-SPDP for benign or low-grade malignant disease were included...
January 12, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28089364/the-impact-of-neoadjuvant-chemotherapy-on-skeletal-muscle-depletion-and-preoperative-sarcopenia-in-patients-with-resectable-colorectal-liver-metastases
#4
Sam Eriksson, Jan H Nilsson, Peter Strandberg Holka, Jakob Eberhard, Inger Keussen, Christian Sturesson
BACKGROUND: Preoperative skeletal muscle depletion or sarcopenia has been suggested to predict worse outcome after resection of colorectal liver metastases. The aim of the present study was to investigate the impact of neoadjuvant chemotherapy on preoperative skeletal muscle mass prior to liver resection. METHODS: Patients operated with liver resection for colorectal liver metastases between 2010 and 2014 were retrospectively reviewed. Muscle mass was evaluated by measuring muscle area on a cross-sectional computed tomography image at the level of the third lumbar vertebra, and normalized for patient height, presenting a skeletal muscle index...
January 11, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28087319/biliary-fistula-after-pancreaticoduodenectomy-data-from-1618-consecutive-pancreaticoduodenectomies
#5
Stefano Andrianello, Giovanni Marchegiani, Giuseppe Malleo, Tommaso Pollini, Deborah Bonamini, Roberto Salvia, Claudio Bassi, Luca Landoni
BACKGROUND: Biliary fistula (BF) occurs in 3-8% of patients following pancreaticoduodenectomy (PD). It usually pursues a benign course, but rarely may represent a life-threatening event. STUDY DESIGN: Data from 1618 PDs were collected prospectively. BF was defined as the presence of bile stained fluid from drains by post-operative day 3 and confirmed by sinogram in the majority of cases. Three classifications were validated. RESULTS: BF occurred in 58 (3...
January 11, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28065427/systematic-review-on-the-treatment-of-isolated-local-recurrence-of-pancreatic-cancer-after-surgery-re-resection-chemoradiotherapy-and-sbrt
#6
REVIEW
Vincent P Groot, Hjalmar C van Santvoort, Steffi J E Rombouts, Jeroen Hagendoorn, Inne H M Borel Rinkes, Marco van Vulpen, Joseph M Herman, Christopher L Wolfgang, Marc G Besselink, I Quintus Molenaar
BACKGROUND: The majority of patients who have undergone a pancreatic resection for pancreatic cancer develop disease recurrence within two years. In around 30% of these patients, isolated local recurrence (ILR) is found. The aim of this study was to systematically review treatment options for this subgroup of patients. METHODS: A systematic search was performed in PubMed, Embase and the Cochrane Library. Studies reporting on the treatment of ILR after initial curative-intent resection of primary pancreatic cancer were included...
January 3, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28043763/prediction-of-the-total-liver-weight-using-anthropological-clinical-parameters-does-complexity-result-in-better-accuracy
#7
Marc-Antoine Allard, Gaëlle Baillié, Carlos Castro-Benitez, Matthieu Faron, Frédérique Blandin, Daniel Cherqui, Denis Castaing, Antonio Sa Cunha, René Adam, Éric Vibert
BACKGROUND: The performance of linear models predicting Total Liver Weight (TLW) remains moderate. The use of more complex models such as Artificial Neural Network (ANN) and Generalized Additive Model (GAM) or including the variable "steatosis" may improve TLW prediction. This study aimed to assess the value of ANN and GAM and the influence of steatosis for predicting TLW. METHODS: Basic clinical and morphological variables of 1560 cadaveric donors for liver transplantation were randomly split into a training (2/3) and validation set (1/3)...
December 30, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28040426/re-gavriilidis-et%C3%A2-al-survival-following-redo-hepatectomy-vs-radiofrequency-ablation-for-recurrent-hepatocellular-carcinoma-a-systematic-review-and-meta-analysis
#8
LETTER
Simon Erridge, Mikael H Sodergren, Long R Jiao
No abstract text is available yet for this article.
December 29, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28038967/pancreatoduodenectomy-with-venous-or-arterial-resection-a-nsqip-propensity-score-analysis
#9
Joal D Beane, Michael G House, Susan C Pitt, Ben Zarzaur, E Molly Kilbane, Bruce L Hall, Taylor S Riall, Henry A Pitt
INTRODUCTION: Vascular resection during pancreatoduodenectomy (PD) is being performed more frequently. Our aim was to analyze the outcomes of PD with and without vascular resection in a large, multicenter cohort. METHODS: Patient data were gathered from 43 institutions as part of the American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP) Pancreatectomy Demonstration Project. Over a 14-month period, 1414 patients underwent PD without (82...
December 27, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28038966/robotic-approach-mitigates-perioperative-morbidity-in-obese-patients-following-pancreaticoduodenectomy
#10
Mark D Girgis, Mazen S Zenati, Jennifer Steve, David L Bartlett, Amer Zureikat, Herbert J Zeh, Melissa E Hogg
INTRODUCTION: The aim was to evaluate the impact of obesity on perioperative outcomes in patients undergoing robotic pancreaticoduodenectomy (RPD) compared to open pancreaticoduodenectomy (OPD). METHODS: A retrospective review of all pancreaticoduodenectomies from 9/2011 to 4/2015 was performed. Obesity was defined as body mass index (BMI) > 30 kg/m(2). RESULTS: Of 474 pancreaticoduodenectomies performed: RPD = 213 (45%) and OPD = 261 (55%)...
December 27, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27993464/impact-of-medical-or-surgical-admission-on-outcomes-of-patients-with-acute-cholecystitis
#11
Francisco Igor B Macedo, Joseph J Eid, Vijay K Mittal, Jeffrey Flynn, Michael J Jacobs, Ralph Pearlman
BACKGROUND: Although acute cholecystitis (AC) is a surgical disease, patients with the condition may be admitted to medical-related services (MS). This may lead to delayed cholecystectomy thereby affecting outcomes and quality of care. METHODS: Between July 2010 and March 2013, 329 patients under 70 years old presented to a community-based tertiary care hospital with AC and underwent same admission cholecystectomy. Outcomes were compared between patients admitted to MS and surgical services (SS)...
December 16, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27986417/does-a-second-resection-provide-a-survival-benefit-in-patients-diagnosed-with-incidental-t1b-t2-gallbladder-cancer-following-cholecystectomy
#12
Henry Watson, Bobby Dasari, Judy Wyatt, Ernest Hidalgo, Raj Prasad, Peter Lodge, Giles Toogood
BACKGROUND: Incidental T1b/T2 gallbladder cancers are often managed with a second resection. However it is unclear whether the additional surgical risk is associated with any survival advantage. The aim of this study was to examine the outcomes of patients who underwent a second resection following a diagnosis of incidental T1b/T2 gallbladder cancer. METHODS: A retrospective analysis of patients undergoing surgical management following a diagnosis of incidental T1b/T2 gallbladder cancer between 1994 and 2014...
December 13, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27956027/measuring-future-liver-remnant-function-prior-to-hepatectomy-may-guide-the-indication-for-portal-vein-occlusion-and-avoid-posthepatectomy-liver-failure-a-prospective-interventional-study
#13
Thiery Chapelle, Bart Op de Beeck, Geert Roeyen, Bart Bracke, Vera Hartman, Kathleen De Greef, Ivan Huyghe, Thijs Van der Zijden, Stuart Morrison, Sven Francque, Dirk Ysebaert
BACKGROUND: Estimation of the future liver remnant function (eFLRF) can avoid post-hepatectomy liver failure (PHLF). In a previous study, a cutoff value of 2.3%/min/m(2) for eFLRF was a better predictor of PHLF than future liver remnant volume (FLRV%). In this prospective interventional study, investigating a management strategy aimed at avoiding PHLF, this cutoff value was the sole criterion assessing eligibility for hepatectomy, with or without portal vein occlusion (PVO). METHODS: In 100 consecutive patients, eFLRF was determined using the formula: eFLRF = FLRV% × total liver function (TLF)...
December 9, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27956026/laparoscopic-left-lateral-sectionectomy-a-population-based-study
#14
Nathalie Goutte, Noelle Bendersky, Louise Barbier, Bruno Falissard, Olivier Farges
BACKGROUND: Laparoscopic left lateral sectionectomy (LLS) has now become standard practice. However, published series are small and retrospective. The aim was to compare at a national level the use and short-term outcome of laparoscopic and open LLS. METHODS: National hospital discharge databases were screened to identify all adult patients who had undergone elective LLS in France between 2007 and 2012. Outcome measurements included blood transfusion, severe morbidity, mortality and length of hospital stay...
December 9, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27939807/whipple-specific-complications-result-in-prolonged-length-of-stay-not-accounted-for-in-acs-nsqip-surgical-risk-calculator
#15
Brian M Cusworth, Bradley A Krasnick, Timothy M Nywening, Cheryl A Woolsey, Ryan C Fields, Maria M Doyle, Jingxia Liu, William G Hawkins
BACKGROUND: The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) Surgical Risk Calculator was developed to help counsel patients regarding estimated postoperative risk for a variety of surgical complications. This retrospective single institutional study examined the calculator's ability to accurately predict complications and length of hospital stay (LOS) in patients who had undergone a Pancreaticoduodenectomy (PD) at our institution. METHODS: 165 patients at Washington University School of Medicine who underwent a PD from 8/2011 to 7/2013 were included...
December 8, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27916436/utility-of-a-multidisciplinary-tumor-board-in-the-management-of-pancreatic-and-upper-gastrointestinal-diseases-an-observational-study
#16
David G Brauer, Matthew S Strand, Dominic E Sanford, Vladimir M Kushnir, Kian-Huat Lim, Daniel K Mullady, Benjamin R Tan, Andrea Wang-Gillam, Ashley E Morton, Marianna B Ruzinova, Parag J Parikh, Vamsi R Narra, Kathryn J Fowler, Majella B Doyle, William C Chapman, Steven S Strasberg, William G Hawkins, Ryan C Fields
BACKGROUND & OBJECTIVES: Multidisciplinary tumor boards (MDTBs) are frequently employed in cancer centers but their value has been debated. We reviewed the decision-making process and resource utilization of our MDTB to assess its utility in the management of pancreatic and upper gastrointestinal tract conditions. METHODS: A prospectively-collected database was reviewed over a 12-month period. The primary outcome was change in management plan as a result of case discussion...
December 1, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27914765/operative-morbidity-and-survival-following-hepatectomy-for-colorectal-liver-metastasis-in-octogenarians-a-contemporary-case-matched-series
#17
Julie N Leal, Eran Sadot, Mithat Gonen, Stuart Lichtman, T Peter Kingham, Peter J Allen, Ronald P DeMatteo, William R Jarnagin, Michael I D'Angelica
BACKGROUND: Clinical outcomes of octogenarians undergoing hepatectomy for colorectal liver metastases (CRLM) are poorly characterized. The current study evaluated operative morbidity, mortality and survival outcomes among a contemporary cohort of octogenarians. METHODS: Patients undergoing their first hepatectomy for CRLM were identified from institutional databases and those ≥80 years old (y) were matched 1:1 to a group of patients <80 y. Data pertaining to surgical morbidity/mortality and survival were compared using standard statistical methods...
November 30, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27914764/enhanced-recovery-pathway-in-patients-undergoing-distal-pancreatectomy-a-case-matched-study
#18
Nicolò Pecorelli, Giovanni Capretti, Gianpaolo Balzano, Renato Castoldi, Marianna Maspero, Luigi Beretta, Marco Braga
BACKGROUND: Enhanced recovery (ER) pathways have improved outcomes across multiple surgical specialties, but reports concerning their application in distal pancreatectomy (DP) are lacking. The aim of this study was to assess compliance with an ER protocol and its impact on short-term outcomes in patients undergoing DP. METHODS: Prospectively collected data were reviewed. One hundred consecutive patients undergoing DP were treated within an ER pathway comprising 18 care elements...
November 30, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27914763/management-of-suspected-common-bile-duct-stone-diagnostic-yield-of-current-guideline
#19
Ufuk B Kuzu, Bülent Ödemiş, Selçuk Dişibeyaz, Erkan Parlak, Erkin Öztaş, Fatih Saygılı, Hakan Yıldız, Mustafa Kaplan, Orhan Coskun, Adem Aksoy, Derya Arı, Nuretdin Suna, Ertuğrul Kayaçetin
BACKGROUND: The American Society for Gastrointestinal Endoscopy (ASGE) has recently published a guideline for suspected CBDS with the intention of reducing unnecessary ERCP and thereby complications. The aim of this study was to assess the diagnostic efficacy of the ASGE guideline. METHODS: Data of patients who underwent ERCP with suspected CBDS were analyzed retrospectively. Patients were classified into high, intermediate and low risk groups based on predictors that have been suggested by the ASGE...
November 30, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27894845/thromboelastography-demonstrates-perioperative-hypercoagulability-in-hepato-pancreato-biliary-patients-and-supports-routine-administration-of-preoperative-and-early-postoperative-venous-thromboembolism-chemoprophylaxis
#20
Anh-Thu Le, Jennifer W Harris, Erin Maynard, Sean P Dineen, Ching-Wei D Tzeng
BACKGROUND: We hypothesized hepato-pancreato-biliary (HPB) surgery patients are more likely to be hypercoagulable than hypocoagulable, and that bleeding risks from VTE chemoprophylaxis are low. This study sought to use thromboelastography (TEG) to compare coagulation profiles with bleeding/thrombotic events in HPB patients receiving standardized perioperative chemoprophylaxis. METHODS: Consecutive patients undergoing HPB resections by three surgeons at one institution (January 2014-December 2015) received preoperative and early postoperative VTE chemoprophylaxis and were evaluated with TEGs...
November 25, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
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