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HPB: the Official Journal of the International Hepato Pancreato Biliary Association

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https://www.readbyqxmd.com/read/29331277/unplanned-reoperation-after-hepatectomy-an-analysis-of-risk-factors-and-outcomes
#1
Heather G Lyu, Gaurav Sharma, Ethan Y Brovman, Julius Ejiofor, Richard D Urman, Jason S Gold, Edward E Whang
BACKGROUND/PURPOSE: Reoperation is being increasingly utilized as a metric for surgical care quality. The aim of this study was to identify the incidence of and risk factors for unplanned reoperation following index hepatectomy. METHODS: Pre, intra- and post-operative information of patients who underwent partial hepatectomy in 435 hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program from 2011 to 2013 were analyzed...
January 11, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29317157/laparoscopic-liver-resection-for-hepatocellular-carcinoma-in-early-and-advanced-cirrhosis
#2
Rachel E Beard, Yisi Wang, Sidrah Khan, J Wallis Marsh, Allan Tsung, David A Geller
BACKGROUND: Laparoscopic liver resection for hepatocellular carcinoma is well described in early cirrhosis. Less is known regarding outcomes with more advanced cirrhosis, and this study aimed to compare these groups. METHODS: A retrospective review of resections at a high-volume hepatobiliary center over a 15-year period was performed. Primary end-points were 30 and 90-day mortality. Secondary end-points included complications and survival. RESULTS: 80 early (Child's A) were compared to 26 advanced (20 Child's B and 6 Child's C) patients...
January 6, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29307511/acinar-cell-density-at-the-pancreatic-resection-margin-is-associated-with-post-pancreatectomy-pancreatitis-and-the-development-of-postoperative-pancreatic-fistula
#3
Christopher B Nahm, Kai M Brown, Philip J Townend, Emily Colvin, Viive M Howell, Anthony J Gill, Saxon Connor, Jaswinder S Samra, Anubhav Mittal
BACKGROUND: There has been recent evidence supporting post-pancreatectomy pancreatitis as a factor in the development of postoperative pancreatic fistula (POPF). The aims of this study were to evaluate: (i) the correlation of the acinar cell density at the pancreatic resection margin with the intra-operative amylase concentration (IOAC) of peri-pancreatic fluid, postoperative pancreatitis, and POPF; and (ii) the association between postoperative pancreatitis on the first postoperative day and POPF...
January 5, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29306581/pringle-maneuver-increases-the-risk-of-anastomotic-leakage-after-colonic-resection-in-rats
#4
Boris Jansen-Winkeln, Evangelos Tagkalos, Axel Heimann, Timo Gaiser, Daniela Hirsch, Ines Gockel, Jens Mittler, Hauke Lang, Stefan Heinrich
BACKGROUND: Many centers use the Pringle's maneuver during liver resections. Since this maneuver might impair healing of bowel anastomoses, we evaluated its influence on the healing of colonic anastomosis in rats. METHODS: Male Wistar rats underwent median laparotomy and sigmoid resection with end-to-end anastomosis under inhalation anesthesia. Thereafter, rats received a 25 minutes Pringle's maneuver (PM, group 1) or were kept under anesthesia for the same period of time (group 2)...
January 3, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29292071/near-infrared-fluorescent-cholangiography-real-time-visualization-of-the-biliary-tree-during-elective-laparoscopic-cholecystectomy
#5
Antonio Pesce, Saverio Latteri, Martina Barchitta, Teresa R Portale, Biagio Di Stefano, Antonella Agodi, Domenico Russello, Stefano Puleo, Gaetano La Greca
BACKGROUND: The purpose was to evaluate the efficacy of near-infrared fluorescent cholangiography (FC) in real-time visualization of the biliary tree during elective laparoscopic cholecystectomy. METHODS: Fifty consecutive elective laparoscopic cholecystectomies were performed with fluorescent cholangiography. FC was performed at three time points: following exposure of Calot's triangle, prior to any dissection; and after partial and complete dissection of Calot's triangle...
December 29, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29287736/prospective-evaluation-of-the-international-study-group-for-liver-surgery-definition-of-post-hepatectomy-liver-failure-after-liver-resection-an-international-multicentre-study
#6
Asma Sultana, Mark Brooke-Smith, Shahid Ullah, Joan Figueras, Myrddin Rees, Jean-Nicolas Vauthey, Claudius Conrad, Thomas J Hugh, O James Garden, Sheung T Fan, Michael Crawford, Masatoshi Makuuchi, Yukihiro Yokoyama, Markus Büchler, Robert Padbury
BACKGROUND: The International Study Group for Liver Surgery (ISGLS) definition of post hepatectomy liver failure (PHLF) was developed to be consistent, widely applicable, and to include severity stratification. This international multicentre collaborative study aimed to prospectively validate the ISGLS definition of PHLF. METHODS: 11 HPB centres from 7 countries developed a standardised reporting form. Prospectively acquired anonymised data on liver resections performed between 01 July 2010 and 30 June 2011 was collected...
December 26, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29249649/systematic-review-on-the-impact-of-pancreatoduodenectomy-on-quality-of-life-in-patients-with-pancreatic-cancer
#7
REVIEW
Sven M van Dijk, Hanne D Heerkens, Dorine S J Tseng, Martijn Intven, I Quintus Molenaar, Hjalmar C van Santvoort
BACKGROUND: Patients undergoing pancreatoduodenectomy for pancreatic cancer have a high risk of major postoperative complications and a low survival rate. Insight in the impact of pancreatoduodenectomy on quality of life (QoL) is therefore of great importance. The aim of this systematic review was to assess QoL after pancreatoduodenectomy for pancreatic cancer. METHODS: A systematic review of the literature was performed according to the PRISMA guidelines. A systematic search of all the English literature available in PubMed and Medline was performed...
December 14, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29248401/health-economic-implications-of-complications-associated-with-pancreaticoduodenectomy-at-a-university-hospital-a%C3%A2-retrospective-cohort-cost-study
#8
Jason Wang, Ronald Ma, Paul Eleftheriou, Leonid Churilov, David Debono, Ray Robbins, Mehrdad Nikfarjam, Chris Christophi, Laurence Weinberg
BACKGROUND: A cost analyses of complications following pancreaticoduodenectomy (PD) was performed in a high volume hepato-biliary-pancreatic service. We hypothesised that costs are increased with both severity and number of complications; we investigated the relationship between complications and specific cost centres. METHODS: 100 patients from 2011 to 2016 were included. Data relating to their perioperative course were collected. Complications were documented by the Clavien-Dindo classification and costs were inflated and converted to 2017 USD...
December 13, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29248400/the-risk-of-incidental-gallbladder-cancer-is-negligible-in-macroscopically-normal-cholecystectomy-specimens
#9
Hanna Koppatz, Arno Nordin, Tom Scheinin, Ville Sallinen
BACKGROUND: Cholecystectomy is usually carried out for benign indications. Most perform routine histopathologic examination to detect incidental gallbladder cancer (GBC). METHODS: Cholecystectomies performed at four hospitals in the Helsinki Metropolitan Area during 2010-2012 were analyzed retrospectively. Patients with preoperative suspicion of neoplasia, active malignancy, or in whom cholecystectomy was performed as a secondary procedure were excluded. RESULTS: A total of 2034 cholecystectomies were included...
December 13, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29242035/outcomes-of-liver-first-strategy-and-classical-strategy-for-synchronous-colorectal-liver-metastases-in-sweden
#10
Valentinus T Valdimarsson, Ingvar Syk, Gert Lindell, Agneta Norén, Bengt Isaksson, Per Sandström, Magnus Rizell, Bjarne Ardnor, Christian Sturesson
BACKGROUND: Patients with synchronous colorectal liver metastases (sCRLM) are increasingly operated with liver resection before resection of the primary cancer. The aim of this study was to compare outcomes in patients following the liver-first strategy and the classical strategy (resection of the bowel first) using prospectively registered data from two nationwide registries. METHODS: Clinical, pathological and survival outcomes were compared between the liver-first strategy and the classical strategy (2008-2015)...
December 11, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29221789/pretherapy-neutrophil-to-lymphocyte-ratio-and-platelet-to-lymphocyte-ratio-do-not-predict-survival-in-resectable-pancreatic-cancer
#11
Akhil Chawla, Tiffany L Huang, Andrew M Ibrahim, Jeffrey M Hardacre, Christopher Siegel, John B Ammori
BACKGROUND: Pretherapy serum neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have both been identified as prognostic in pancreatic ductal adenocarcinoma (PDAC). The aim of this study was to identify the prognostic implication of pretherapy NLR and PLR in patients with resectable PDAC. METHODS: Data were collected retrospectively on patients operated at our institution between 2004 and 2014. A Cox proportional hazards model was used to investigate the relationship between clinical and pathological parameters, NLR and PLR to overall survival (OS)...
December 5, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29208352/multicentre-study-of-the-impact-of-factors-that-may-affect-long-term-survival-following-pancreaticoduodenectomy-for-distal-cholangiocarcinoma
#12
Laëtitia Courtin-Tanguy, Olivier Turrini, Damien Bergeat, Stéphanie Truant, Benjamin Darnis, Jean R Delpero, Jean Y Mabrut, Nicolas Regenet, Laurent Sulpice
BACKGROUND: Although the peri-operative mortality following pancreaticoduodenectomy (PD) for distal cholangiocarcinoma (DCC) has decreased, the post-operative morbidity remains high. The aim of this study was to evaluate the impact of factors that may affect the long term survival for patients with DCC following PD. METHODS: All patients who underwent PD for DCC between January 2000 and December 2015 in 5 tertiary referral centers underwent retrospective medical record review...
December 2, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29198420/circumportal-pancreas-a-hazardous-anomaly-in-pancreatic-surgery
#13
Ryota Kiuchi, Takashi Mizuno, Yukiyasu Okamura, Teiichi Sugiura, Hideyuki Kanemoto, Katsuhiko Uesaka
BACKGROUND: Circumportal pancreas (CP) is an anatomical anomaly in the form of abnormal parenchymal fusion between the uncinate process and the pancreatic body, and it requires an additional parenchymal dissection during pancreaticoduodenectomy (PD). This study aimed to investigate the prevalence of CP in PD and to evaluate the incidence of postoperative pancreatic fistula (POPF) among CP patients. METHODS: Patients who underwent PD from 2002 to 2012 (n = 552) were included...
November 29, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29196022/a-systematic-review-and-meta-analysis-on-the-role-of-palliative-primary-resection-for-pancreatic-neuroendocrine-neoplasm-with-liver-metastases
#14
REVIEW
Stefano Partelli, Roberto Cirocchi, Paola M V Rancoita, Francesca Muffatti, Valentina Andreasi, Stefano Crippa, Domenico Tamburrino, Massimo Falconi
BACKGROUND: Role of palliative pancreatic neuroendocrine neoplasm (PanNEN) resection (pPanNEN-R) is controversial. This study was designed as a meta-analysis of studies which allow a comparison of pPanNEN-R and non-surgical management (PanNEN-nR). METHODS: All published studies until 2017 allowing for the comparison of pPanNEN-R and PanNEN-nR were reviewed. Primary outcome was overall survival (OS). Secondary outcomes measures included postoperative morbidity, reoperation, readmission, length of hospital stay (LOS), and quality of life (QoL)...
November 29, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29196021/advanced-imaging-to-predict-response-to-chemotherapy-in-colorectal-liver-metastases-a-systematic-review
#15
REVIEW
Rianne C J Beckers, Doenja M J Lambregts, Max J Lahaye, Sheng-Xiang Rao, Kelly Kleinen, Cecile Grootscholten, Geerard L Beets, Regina G H Beets-Tan, Monique Maas
BACKGROUND: The assessment of colorectal liver metastases (CRLM) after treatment with chemotherapy is challenging due to morphological and/or functional change without changes in size. The aim of this review was to assess the value of FDG-PET, FDG-PET-CT, CT and MRI in predicting response to chemotherapy in CRLM. METHODS: A systematic review was undertaken based on PRISMA statement. PubMed and Embase were searched up to October 2016 for studies on the accuracy of PET, PET-CT, CT and MRI in predicting RECIST or metabolic response to chemotherapy and/or survival in patients with CRLM...
November 28, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29191691/assessing-the-impact-of-conversion-on-outcomes-of-minimally-invasive-distal-pancreatectomy-and-pancreatoduodenectomy
#16
Joal D Beane, Henry A Pitt, Scott C Dolejs, Melissa E Hogg, Herbert J Zeh, Amer H Zureikat
BACKGROUND: Our aim was to compare outcomes of patients who undergo conversion to open during minimally invasive distal pancreatectomy (MI-DP) and pancreatoduodenectomy (MI-PD) to those completed in minimally invasive fashion, and to compare outcomes of minimally invasive completions and conversions to planned open pancreatectomy. METHODS: Propensity scoring was used to compare outcomes of completed and converted cases from a national cohort, and multivariate regression analysis (MVA) was used to compare minimally invasive completions and conversions to planned open pancreatectomy...
November 27, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29191690/the-extent-of-vascular-resection-is-associated-with-perioperative-outcome-in-patients-undergoing-pancreaticoduodenectomy
#17
Olga Kantor, Mark S Talamonti, Chi-Hsiung Wang, Kevin K Roggin, David J Bentrem, David J Winchester, Richard A Prinz, Marshall S Baker
BACKGROUND: Few studies have examined the relation between extent of vascular resection and morbidity following pancreaticoduodenectomy (PD) with vein resection (PDVR). METHODS: Patients undergoing PD for malignancy were identified using the American College of Surgeons National Surgical Quality Improvement Project from 2006 to 2013. Current procedural terminology codes were used to characterize PDVR. RESULTS: 9235 patients underwent PD, 977 (10...
November 27, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29191689/does-the-surgical-waiting-list-affect-pathological-and-survival-outcome-in-resectable-pancreatic-ductal-adenocarcinoma
#18
Giovanni Marchegiani, Stefano Andrianello, Giampaolo Perri, Erica Secchettin, Laura Maggino, Giuseppe Malleo, Claudio Bassi, Roberto Salvia
BACKGROUND: High-volume centers have to deal with long surgical waiting-lists leading to a potential delay in treatment. This study assessed whether a longer time from diagnosis to surgery worsened pathological and survival outcomes in resectable pancreatic ductal adenocarcinoma (PDAC). METHODS: A retrospective analysis of patients treated for resectable PDAC. Difference in size between preoperative CT-scan and specimen, pathological features, the rate of vascular and R1 resections as well as recurrence and survival were analyzed depending on the waiting time using a 30-day cut-off...
November 27, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29187305/liver-resection-for-colorectal-cancer-metastases-a-comparison-of-outcomes-over-time-in-south-australia
#19
Asma Sultana, Rosie Meng, Cynthia Piantadosi, Mark Brooke-Smith, John Chen, Paul Dolan, Guy Maddern, Timothy Price, Robert Padbury
BACKGROUND: The aim of the current study was to assess outcomes following liver resection in metastatic CRC (mCRC) in South Australia across two study periods (pre-2006 versus post-2006). METHODS: The South Australian (SA) Clinical Registry for mCRC maintains data prospectively on all patients in SA with mCRC diagnosed from 01 February 2006. This data was linked with a prospectively collated database on liver resections for mCRC from 01/01/1992 to 01/02/2006. The primary end point was overall survival...
November 26, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29183703/a-comparison-of-outcomes-between-open-laparoscopic-and-robotic-pancreaticoduodenectomy
#20
Asha M Zimmerman, Dean G Roye, Kevin P Charpentier
BACKGROUND: The advantages and comparison of minimally invasive techniques for pancreaticoduodenectomies have not been fully explored using large national multicenter data. STUDY DESIGN: A retrospective review of NSQIP targeted data from 2014 to 2015 was performed. Demographics and outcomes were compared between open (OPD), laparoscopic (LPD) and robotic pancreaticoduodenectomies (RPD). RESULTS: Of 6827 pancreaticoduodenectomies, 6336 (92...
November 25, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
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