journal
MENU ▼
Read by QxMD icon Read
search

Paediatric Respiratory Reviews

journal
https://www.readbyqxmd.com/read/28479112/interventions-to-improve-inhaler-technique-and-adherence-to-inhaled-corticosteroids-in-children-with-asthma
#1
Rebecca Normansell, Kayleigh Kew, Elizabeth Stovold, Alexander G Mathioudakis, Emma Dennett
No abstract text is available yet for this article.
April 8, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28433261/dyspnea-in-children-what-is-driving-it-and-how-to-approach-it
#2
REVIEW
Larry C Lands
Dyspnea in children has important physical and psychosocial impact. It is useful to define the quality of the dyspnea and quantify its magnitude in a child-friendly manner. Through careful history taking and physical examination, a targeted investigation can lead to identification of the cause and potential treatment. This article provides a framework for the clinical approach to dyspnea in children, including important information to gather during the history, physical assessment, how to quantify dyspnea, and choice and use of laboratory measurements...
March 31, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28416135/all-the-rage-in-lung-disease-the-receptor-for-advanced-glycation-endproducts-rage-is-a-major-mediator-of-pulmonary-inflammatory-responses
#3
REVIEW
Elizabeth A Oczypok, Timothy N Perkins, Tim D Oury
The receptor for advanced glycation endproducts (RAGE) is a pro-inflammatory pattern recognition receptor (PRR) that has been implicated in the pathogenesis of numerous inflammatory diseases. It was discovered in 1992 on endothelial cells and was named for its ability to bind advanced glycation endproducts and promote vascular inflammation in the vessels of patients with diabetes. Further studies revealed that RAGE is most highly expressed in lung tissue and spurred numerous explorations into RAGE's role in the lung...
March 18, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28408202/airway-clearance-techniques-for-primary-ciliary-dyskinesia-is-the-cystic-fibrosis-literature-portable
#4
REVIEW
Lynne Marie Schofield, Alistair Duff, Cathy Brennan
Primary Ciliary Dyskinesia (PCD) is a rare inherited disease with impaired mucociliary clearance. Airway clearance techniques (ACTs) are commonly recommended for patients with PCD to facilitate mucus clearance, despite a lack of evidence in this group. Current physiotherapy practice in PCD is based on evidence extrapolated from the field of Cystic Fibrosis (CF). This paper focuses on the available evidence and outlines challenges in extrapolating evidence between the conditions for best clinical practice.
March 16, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28416301/telemedicine-is-the-way-forward-for-the-management-of-cystic-fibrosis-the-case-in-favour-the-debate-telemedicine-is-the-future-for-cf-care
#5
REVIEW
Robert Ian Ketchell
Despite rapid changes in Information and Communication Technology, outpatient chronic disease management has changed very little in decades. However, the introduction of Telemedicine defined here as the use of remote patient-centred clinical services including the use of video and audio connections, telemonitoring and mobile applications provides us with an ideal opportunity to revolutionise care. Its appeal in cystic fibrosis (CF) care is clear offering better access to services, the opportunity of earlier intervention and improved monitoring and self management through virtual clinics and the use of real-time applications for adherence monitoring...
March 15, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28420572/nutritional-management-of-cystic-fibrosis-an-update-for-the-21st-century
#6
REVIEW
Sarah Collins
Nutritional management is an essential part of multidisciplinary care for infants, children and adults with cystic fibrosis (CF). In 2016 two updated nutritional consensus guidelines were published [1,2]. This review will explore some of the key points in the nutritional management of people with CF in the 21st Century.
March 14, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28411069/clostridium-difficile-and-cystic-fibrosis-management-strategies-and-the-role-of-faecal-transplantation
#7
REVIEW
Roisin Dunwoody, Alan Steel, Jonathan Landy, Nicholas Simmonds
Clostridium difficile is a bacterial infection that colonises the gut in susceptible hosts. It is associated with exposure to healthcare settings and antibiotic use. It could be assumed that cystic fibrosis (CF) patients are a high-risk group for C.difficile. However, despite high carriage rates, CF patients have low rates of active disease. There are guidelines for the treatment of C.difficile, however little is published specific to treating C.difficile in CF. This article provides an overview of the current management strategies for C...
March 14, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28400242/the-impact-of-co-morbidity-in-childhood-cystic-fibrosis
#8
REVIEW
Julie A Duncan, Sarah M N Brown
A number of risk factors have been identified for deterioration of lung disease in children with Cystic Fibrosis (CF), and current management strategies are based on the prevention and treatment of such elements. Further challenge ensues when a patient has co-morbid disease in addition to CF, particularly when faced with rapidly deteriorating pulmonary status. It is difficult to measure the contribution of other pathologies to this decline and optimisation of both CF care and co-morbidity is paramount. This review explores the challenges faced when treating children with CF and co-morbid conditions, focussing on gastroesophageal reflux disease pre- and post-lung transplantation...
March 14, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28400241/highlights-from-the-30th-north-american-cystic-fibrosis-conference-orlando-2016
#9
REVIEW
Anna Shawcross, Peter J Barry
This is a selection of papers presented at the 30th North American Cystic Fibrosis Conference held in Orlando in October 2016. The papers discussed are thought to be of particular interest to CF caregivers in the UK. We highlight the major themes covered in the conference including novel therapies, recently published and proposed guidelines and insights from registry studies.
March 14, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28366680/telemedicine-is-the-way-forward-for-the-management-of-cystic-fibrosis-the-case-against
#10
REVIEW
Warren Lenney
It is reasonable to suggest that Telemedicine could help in the management of chronic diseases by giving patients more flexibility to remain at home with opportunities to forward electronic data to healthcare professionals, reduce hospital emergency attendances and reduce overall costs. The reality, particularly in cystic fibrosis care, is this has not happened. There is concern that home-generated lung function data is of poor quality and virtually no studies show improved outcomes. The UK has a poor record in developing novel IT programmes and we need many more well designed clinical studies in Telemedicine before wading in with ill-conceived expensive plans just because the idea seems interesting...
March 14, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28372929/cystic-fibrosis-in-the-era-of-precision-medicine
#11
REVIEW
Shruti M Paranjape, Peter J Mogayzel
The treatment of people with cystic fibrosis (CF) has been transformed by the availability of drugs that target the basic chloride defect in the disease. The use of drugs that target specific molecular defects embodies the goals of precision medicine, which incorporate preventive and therapeutic strategies and takes into account differences among individuals. However, the entirety of CF care, from diagnosis to understanding the clinical phenotype and developing a therapeutic strategy, depends on taking into account individual characteristics to achieve optimal outcomes...
March 9, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28341168/lies-damned-lies-and-statistics-clinical-importance-versus-statistical-significance-in-research
#12
REVIEW
Craig Mellis
Correctly performed and interpreted statistics play a crucial role for both those who 'produce' clinical research, and for those who 'consume' this research. Unfortunately, however, there are many misunderstandings and misinterpretations of statistics by both groups. In particular, there is a widespread lack of appreciation for the severe limitations with p values. This is a particular problem with small sample sizes and low event rates - common features of many published clinical trials. These issues have resulted in increasing numbers of false positive clinical trials (false 'discoveries'), and the well-publicised inability to replicate many of the findings...
February 28, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28237418/micrornas-in-lung-development-and-disease
#13
REVIEW
Dustin Ameis, Naghmeh Khoshgoo, Barbara M Iwasiow, Phillip Snarr, Richard Keijzer
MicroRNAs (miRNAs) are small (∼22 nucleotides), non-coding RNA molecules that regulate gene expression post-transcriptionally by inhibiting target mRNAs. Research into the roles of miRNAs in lung development and disease is at the early stages. In this review, we discuss the role of miRNAs in pediatric respiratory disease, including cystic fibrosis, asthma, and bronchopulmonary dysplasia.
March 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28139427/tobacco-vaccine-preventable-diseases-and-malnutrition-more-to-be-done-to-prevent-respiratory-disease
#14
EDITORIAL
Dominic A Fitzgerald
No abstract text is available yet for this article.
March 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28029591/cardiorespiratory-interactions-in-paediatrics-it-s-almost-always-the-circulation-stupid
#15
REVIEW
M L Rigby, M Rosenthal
The interaction of the heart and lungs is probably the most important aspect of life and survival. Fortunately, it is not difficult to understand the fundamentals. The purpose of the lungs and their ventilation is to present oxygen to the circulation via the alveoli and to receive carbon dioxide from the circulation and then expel it. The relations of the heart and lungs and the matching of blood flow to the various organs with ventilation and lung perfusion may be disrupted by a variety of congenital or acquired heart malformations...
March 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/27964951/topical-cystic-fibrosis-transmembrane-conductance-regulator-gene-replacement-for-cystic-fibrosis-related-lung-disease
#16
L A Perry, J C Penny-Dimri, A A Aslam, T W Lee, K W Southern
No abstract text is available yet for this article.
March 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/27843119/potential-nutrients-for-preventing-or-treating-bronchopulmonary-dysplasia
#17
REVIEW
Liya Ma, Ping Zhou, Josef Neu, Hung-Chih Lin
Bronchopulmonary dysplasia (BPD) is a frequent complication occurring in extremely preterm infants. Despite recent advances in newborn medicine, the incidence of BPD does not appear to have changed markedly, and specific treatments and prevention strategies are still lacking. Nutrition plays an important role in normal lung development and maturation. Malnutrition may delay somatic growth and new alveoli development, thus aggravating pulmonary injury involved in the pathogenesis of BPD. However, few nutrients have been investigated for their potential to mitigate the pathogenesis of BPD...
March 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/27839656/respiratory-complications-in-children-with-prader-willi-syndrome
#18
REVIEW
H-L Tan, D S Urquhart
Prader Willi syndrome, resulting from the partial deletion or lack of expression of a region of genes on the paternal chromosome 15, has a number of phenotypic features which predispose affected patients to ventilatory problems. These include generalised hypotonia, abnormal arousal and ventilatory responses to hypoxia and hypercapnia, scoliosis and frequently, obesity. The spectrum of the resulting respiratory complications thus runs from sleep disordered breathing, to aspiration and respiratory functional impairment...
March 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/27818068/relation-between-asthma-and-sleep-disordered-breathing-in-children-is-the-association-causal
#19
REVIEW
Jose A Castro-Rodriguez, Pablo E Brockmann, Carole L Marcus
Over the last few decades, asthma and sleep disordered breathing (SDB) in children have experienced similar increases in prevalence, and have both been shown to have airway inflammation, leading investigators to postulate an association between asthma and SDB. However, whether this relationship is causal or not needs to be proven. In this manuscript, we use the most widely accepted epidemiologic criteria for causality, the Bradford Hill criteria, to test step-by-step whether the relation between asthma and SBD in children is causal or not...
March 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/27793738/interventions-to-prevent-respiratory-diseases-nutrition-and-the-developing-world
#20
REVIEW
Tasneem Karim, Mohammad Muhit, Gulam Khandaker
Malnutrition is a major cause of morbidity and mortality in developing countries and nutrition plays a critical role in both acute and chronic respiratory conditions. Inadequacies in the nutritional requirements of a developing lung in utero and in early life can compromise the respiratory system integrity and result in poor lung function, reduced protection against infections, greater likelihood of acute illnesses in childhood and chronic illness in adulthood. Nutritional interventions harness great potential in reducing respiratory illness related morbidity and mortality in the developing world...
March 2017: Paediatric Respiratory Reviews
journal
journal
34837
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"