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Journal of Feline Medicine and Surgery

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https://www.readbyqxmd.com/read/28206810/safety-of-oral-and-intravenous-mycophenolate-mofetil-in-healthy-cats
#1
Jennifer E Slovak, Nicolas F Villarino
Objectives The aim of this study was to evaluate the safety and clinical effects of intravenous (IV) and oral mycophenolate mofetil (MMF) in healthy cats. Methods A total of 24 healthy adult cats weighing >3.5 kg were either administered IV MMF (over a 2 h infusion) or oral MMF. The dosages used were as follows: 5 mg/kg IV once (n = 2), 10 mg/kg q12h IV for 1 day (n = 1), 20 mg/kg q12h IV for 1 day (n = 6) and 10 mg/kg q12h IV for 3 days (n = 5). Blood was collected from each cat at intervals of up to 12 h from the last dose for analysis purposes...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28195504/postponement-of-puberty-in-queens-treated-with-deslorelin
#2
Marta Cecchetto, Paola Salata, Anna Baldan, Chiara Milani, Antonio Mollo, Christelle Fontaine, Hasan Sontas, Donatella Gelli, Giulia De Benedictis, Calogero Stelletta, Stefano Romagnoli
Objectives The purpose of this study was to assess efficacy of deslorelin, a gonadotropin-releasing hormone (GnRH) agonist marketed in Europe for the control of male dog reproduction, for the postponement of puberty in queens. Methods Nine prepubertal queens aged 3-9 months were selected for this study; their general and reproductive health was checked through clinical, haematological, vaginal cytology and hormonal tests. Following treatment with a 4.7 mg deslorelin implant each cat received a monthly clinical examination and blood was collected for hormonal assay every third month...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28186425/influence-of-two-administration-rates-of-propofol-at-induction-of-anaesthesia-on-its-relative-potency-in-cats-a-pilot-study
#3
Sébastien H Bauquier, Wendy Bayldon, Leon N Warne, Jennifer E Carter, Thierry Beths
Objectives This was a randomised, blinded trial to investigate the influence of administration rate on the dose of propofol required for the orotracheal intubation of cats. Methods Twenty-four female domestic cats undergoing ovariohysterectomy were premedicated with oral tramadol (6 mg/kg) or intramuscular tramadol (4 mg/kg), and intramuscular dexmedetomidine (0.007 mg/kg). Oral or intramuscular (IM) tramadol was administered 60 or 30 mins prior to induction of anaesthesia, respectively. Dexmedetomidine was administered 30 mins prior to anaesthetic induction...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28186424/defining-local-nerve-blocks-for-feline-distal-pelvic-limb-surgery-a-cadaveric-study
#4
Masataka Enomoto, B Duncan X Lascelles, Mathew P Gerard
Objectives Anatomical and methodological detail is lacking regarding local anesthetic peripheral nerve block techniques for distal pelvic limb surgery in cats. The aim of this study was to develop, describe and test nerve block methods based on cadaveric dissections and dye injections. Methods Ten pairs of feline pelvic limbs (n = 20) were dissected and the tibial nerve (T n.), common fibular (peroneal) nerve (CF n., and its two branches, the superficial fibular [peroneal] nerve [SpF n.] and the deep fibular [peroneal] nerve [DpF n...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28181856/repeatability-of-quantitative-sensory-testing-in-healthy-cats-in-a-clinical-setting-with-comparison-to-cats-with-osteoarthritis
#5
Elena S Addison, Dylan N Clements
Objectives The aim of this study was to evaluate the repeatability of quantitative sensory tests (QSTs) in a group of healthy untrained cats (n = 14) and to compare the results with those from cats with osteoarthritis (n = 7). Methods Peak vertical force (PVF) and vertical impulse were measured on a pressure plate system. Thermal sensitivity was assessed using a temperature-controlled plate at 7°C and 40°C. Individual paw lifts and overall duration of paw lifts were counted and measured for each limb. Paw withdrawal thresholds were measured using manual and electronic von Frey monofilaments (MVF and EVF, respectively) applied to the metacarpal or metatarsal pads...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28176530/effects-of-castration-on-penile-extracellular-matrix-morphology-in-domestic-cats
#6
Nathalia Cs Borges, Marco A Pereira-Sampaio, Vivian Alves Pereira, Marcelo Abidu-Figueiredo, Maurício Alves Chagas
Objectives This study was undertaken to verify the possible modifications caused by hormonal deprivation in the extracellular matrix in the penises of neutered cats. Methods Twenty-seven penises from domestic shorthair cats were collected: 14 samples from intact cats and 13 from neutered cats. Sections were stained with Weigert's resorcin-fuchsin, hematoxylin and eosin, and picrosirius red. Histomorphometric analysis was performed using light microscopy and image analysis software. The following parameters were analyzed: density of the elastic fibers and collagen fibers in the corpus spongiosum; density of the elastic fibers in the tunica albuginea of the corpus cavernosum and the tunica albuginea of the corpus spongiosum; luminal area of the urethra; area of the corpus spongiosum; area of the corpus cavernosum; and thickness of the urethral epithelium...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28169564/demographics-lifestyle-and-veterinary-care-of-cats-in-australia-and-new-zealand
#7
Laura Johnston, Julia Szczepanski, Phillip McDonagh
Objectives The aim of this survey was to provide up-to-date information on the demographics, lifestyle and veterinary care of cats in Australia and New Zealand. Methods An online survey consisting of 19 questions was created using SurveyMonkey. Cat owners were invited to participate through advertisements in veterinary clinics and social media. Results The average number of cats in a household was two. The majority of cats lived in free-standing houses (78%) in the suburbs (66%). The majority of cats were desexed (94% [49% female neutered; 45% male neutered])...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28164734/cutpoints-for-screening-blood-glucose-concentrations-in-healthy-senior-cats
#8
Mia K Reeve-Johnson, Jacquie S Rand, Dianne Vankan, Stephen T Anderson, Rhett Marshall, John M Morton
Objectives The objectives of this study were to determine the reference interval for screening blood glucose in senior cats, to apply this to a population of obese senior cats, to compare screening and fasting blood glucose, to assess whether screening blood glucose is predicted by breed, body weight, body condition score (BCS), behaviour score, fasting blood glucose and/or recent carbohydrate intake and to assess its robustness to changes in methodology. Methods The study included a total of 120 clinically healthy client-owned cats aged 8 years and older of varying breeds and BCSs...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28156189/feline-glioma-a-retrospective-study-and-review-of-the-literature
#9
Daniel R Rissi, Andrew D Miller
Case series summary This study aimed to evaluate the pathologic and diagnostic features of 13 cases of feline glioma diagnosed at two veterinary diagnostic institutions over 16 years. A retrospective search was conducted using the laboratory information system. Selected cases were reviewed, tumors were classified according to the 2007 World Health Organization Classification of Tumours of the Central Nervous System, and tissue sections were submitted to an immunohistochemistry panel for further characterization...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28152671/determination-of-multidirectional-myocardial-deformations-in-cats-with-hypertrophic-cardiomyopathy-by-using-two-dimensional-speckle-tracking-echocardiography
#10
Ryohei Suzuki, Yohei Mochizuki, Hiroki Yoshimatsu, Takahiro Teshima, Hirotaka Matsumoto, Hidekazu Koyama
Objectives Hypertrophic cardiomyopathy, a primary disorder of the myocardium, is the most common cardiac disease in cats. However, determination of myocardial deformation with two-dimensional speckle-tracking echocardiography in cats with various stages of hypertrophic cardiomyopathy has not yet been reported. This study was designed to measure quantitatively multidirectional myocardial deformations of cats with hypertrophic cardiomyopathy. Methods Thirty-two client-owned cats with hypertrophic cardiomyopathy and 14 healthy cats serving as controls were enrolled and underwent assessment of myocardial deformation (peak systolic strain and strain rate) in the longitudinal, radial and circumferential directions...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28151047/minimum-transmission-time-of-cytauxzoon-felis-by-amblyomma-americanum-to-domestic-cats-in-relation-to-duration-of-infestation-and-investigation-of-ingestion-of-infected-ticks-as-a-potential-route-of-transmission
#11
Jennifer E Thomas, Cameon M Ohmes, Mark E Payton, Joseph A Hostetler, Mason V Reichard
Objectives The objectives of the present study were to determine the duration of infestation by Amblyomma americanum necessary for transmission of Cytauxzoon felis to domestic cats and to determine if ingestion of C felis-infected A americanum by cats is a route of transmission. Methods Forty-nine cats were assigned to one of seven groups, with seven cats per group. Cats were infested with A americanum adults, acquisition fed as nymphs on a cytauxzoonosis survivor cat, for 12 h (group 1), 18 h (group 2), 24 h (group 3), 36 h (group 4), 48 h (group 5) and to repletion (group 7; control)...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28128683/oral-cobalamin-supplementation-in-cats-with-hypocobalaminaemia-a-retrospective-study
#12
Linda Toresson, Joerg M Steiner, Gunilla Olmedal, MajBritt Larsen, Jan S Suchodolski, Thomas Spillmann
Objectives The objective was to evaluate whether oral cobalamin supplementation can restore normocobal-aminaemia in cats with hypocobalaminaemia and clinical signs of gastrointestinal disease. Methods This was a retrospective study based on a computerised database search for client-owned cats treated at Evidensia Specialist Animal Hospital, Helsingborg, Sweden, during the period December 2013 to August 2016. Inclusion criteria were cats with clinical signs of chronic enteropathy, an initial serum cobalamin concentration ⩽250 pmol/l (reference interval 214-738 pmol/l) and oral treatment with cobalamin tablets...
January 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28128682/percutaneous-cholecystocentesis-in-cats-with-suspected-hepatobiliary-disease
#13
Victoria L Byfield, Julie E Callahan Clark, Bradley J Turek, Charles W Bradley, Mark P Rondeau
Objectives The objective was to evaluate the safety and diagnostic utility of percutaneous ultrasound-guided cholecystocentesis (PUC) in cats with suspected hepatobiliary disease. Methods Medical records of 83 cats with suspected hepatobiliary disease that underwent PUC were retrospectively reviewed. Results At the time of PUC, at least one additional procedure was performed in 79/83 cats, including hepatic aspiration and/or biopsy (n = 75) and splenic aspiration (n = 18). Complications were noted in 14/83 cases, including increased abdominal fluid (n = 11), needle-tip occlusion (n = 1), failed first attempt to penetrate the gall bladder wall (n = 1) and pneumoperitoneum (n = 1)...
January 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28121211/heated-intravenous-fluids-alone-fail-to-prevent-hypothermia-in-cats-under-general-anaesthesia
#14
Geraldine Jourdan, Caroline Didier, Erwan Chotard, Sandra Jacques, Patrick Verwaerde
Objectives The objective was to evaluate the clinical efficiacy of a constant rate infusion of heated fluid as the sole means of preventing intraoperative hypothermia in cats. Methods This randomised, prospective, clinical study was conducted at a university teaching veterinary hospital. Female cats (American Society of Anesthesiologists [ASA] grade I) undergoing elective surgery by laparotomy under general anaesthesia (acepromazine 0.05 mg/kg SC; morphine 0.2 mg/kg IV; propofol IV titrated, isoflurane 2% in 100% oxygen) were randomised in two groups...
January 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28112565/subclinical-bacteriuria-in-cats-prevalence-findings-on-contemporaneous-urinalyses-and-clinical-risk-factors
#15
Melanie L Puchot, Audrey K Cook, Caitlin Pohlit
Objectives Subclinical bacteriuria (SB) is bacterial colonization of the urinary tract in the absence of clinical signs. The purposes of this study were to determine the prevalence of SB in cats and to describe results of the contemporaneous urinalysis. Secondarily, patient characteristics associated with SB were compared with those for cats without SB. Methods An electronic search identified all urine cultures performed on cats at a teaching hospital between 2009 and 2015. Results were subcategorized based on the presence or absence of lower urinary tract disease (LUTD) and SB-positive cases identified...
January 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28112564/frequency-clinicopathological-features-and-phylogenetic-analysis-of-feline-morbillivirus-in-cats-in-istanbul-turkey
#16
Huseyin Yilmaz, Bilge K Tekelioglu, Aydin Gurel, Ozge E Bamac, Gulay Y Ozturk, Utku Y Cizmecigil, Eda A Tarakci, Ozge Aydin, Aysun Yilmaz, Eduardo Berriatua, Chris R Helps, Juergen A Richt, Nuri Turan
Objectives The aim of the study was to investigate feline morbillivirus (FmoPV) frequency, phylogeny and associated pathology in cats in Istanbul, Turkey. Methods Samples from sick (n = 96) and dead ( n = 15) cats were analysed using reverse transcription PCR. Blood and urine analyses and histopathology were also performed. Results FmoPV RNA was detected in six cats (5.4%), including three sick (in the urine) and three dead cats (tissues). A significantly greater proportion of FmoPV RNA-positive cats had street access compared with non-infected cats...
January 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28112563/assessment-of-absorption-of-transdermal-ondansetron-in-normal-research-cats
#17
Lara B Zajic, Andrea K Herndon, Liberty G Sieberg, Amber L Caress, Paula K Morgan, Ryan J Hansen, Luke A Wittenburg, Daniel L Gustafson, Jessica M Quimby
Objectives The objective of this study was to assess the absorption of transdermal ondansetron in healthy cats. Methods Five research cats with unremarkable complete blood count, biochemistry and urinalysis were used for both single- and multiple-dose application studies. For single-dose application, 4 mg ondansetron in 0.1 ml Lipoderm gel was applied once to the internal ear pinna. Blood samples were collected via jugular catheter over a 48 h period following administration (0, 15 mins, 30 mins, 1 h, 2 h, 4 h, 8 h, 12 h, 24 h and 48 h)...
January 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28102730/alloimmunisation-in-transfused-patients-serial-cross-matching-in-a-population-of-hospitalised-cats
#18
Layla Hourani, Christiane Weingart, Barbara Kohn
Objectives Cross-matching is currently recommended as part of pre-transfusion testing for repeat transfusions in cats 4 days after having received an initial transfusion. This prospective study determined when and if cats developed positive cross-match (CM) results after having been transfused with AB-compatible blood. Methods Donors were selected according to standard transfusion safety protocols. Twenty-one hospitalised anaemic recipients (blood type A: n = 20; blood type B: n = 1) received 1-4 (median 2) whole-blood transfusions (WBTs) over 1-6 days (median 2) in 33 transfusion instances...
January 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28094661/diagnosis-of-pancreatic-disease-in-feline-platynosomosis
#19
Liza S Köster, Linda Shell, Jennifer Ketzis, Sreekumari Rajeev, Oscar Illanes
Objectives Platynosomum species are cat-specific parasitic trematodes that parasitize the biliary ducts and gall bladder. Due to the common connection to the major duodenal papilla of the pancreas and common bile ducts in addition to the periductal proximity of the pancreas, it is possible that platynosomosis could cause pancreatitis. The objective of this study was to determine whether platynosomosis, a commonly diagnosed parasitic disease in cats on St Kitts, has any association with pancreatic disease. Methods To investigate this possibility, the pancreas of free-roaming cats with naturally acquired platynosomosis were evaluated via ultrasound, serum concentrations of feline pancreatic lipase (fPL), cobalamin, folate and feline trypsin-like immunoreactivity (fTLI) and histopathology...
January 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28245741/isfm-consensus-guidelines-on-the-diagnosis-and-management-of-hypertension-in-cats
#20
Samantha S Taylor, Andrew H Sparkes, Katherine Briscoe, Jenny Carter, Salva Cervantes Sala, Rosanne E Jepson, Brice S Reynolds, Brian A Scansen
Practical relevance: Feline hypertension is a common disease in older cats that is frequently diagnosed in association with other diseases such as chronic kidney disease and hyperthyroidism (so-called secondary hypertension), although some cases of apparent primary hypertension are also reported. The clinical consequences of hypertension can be severe, related to 'target organ damage' (eye, heart and vasculature, brain and kidneys), and early diagnosis followed by appropriate therapeutic management should help reduce the morbidity associated with this condition...
March 2017: Journal of Feline Medicine and Surgery
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