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Clinical & Experimental Ophthalmology

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https://www.readbyqxmd.com/read/28516476/massive-retinal-gliosis-with-episcleral-extension
#1
LETTER
Bridget Copson, Penelope A McKelvie, Jwu Jin Khong
No abstract text is available yet for this article.
May 18, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28516453/dba-2j-mouse-model-for-experimental-glaucoma-pitfalls-and-problems
#2
Anita J Turner, Roshana Vander Wall, Vivek Gupta, Alex Klistorner, Stuart L Graham
PURPOSE: The DBA/2J mouse has been described as a model for congenital experimental glaucoma. It develops anterior segment anomalies with synechiae and pigment dispersion leading to raised intraocular pressure (IOP) and glaucomatous damage. However there are serious practical considerations when using this model in longitudinal studies. METHODS: We followed 118 mice from 12 - 48 weeks of age in a pharmaceutical trial. Here we report on the findings in control animals (n=37)...
May 18, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28512919/influence-of-serum-lipids-on-the-incidence-and-progression-of-diabetic-retinopathy-and-macular-oedema-sankara-nethralaya-diabetic-retinopathy-epidemiology-and-molecular-genetics-study-sn-dreams-ii
#3
Sangeetha Srinivasan, Rajiv Raman, Vaitheeswaran Kulothungan, Gayathri Swaminathan, Tarun Sharma
IMPORTANCE: The importance of lipids on incidence and progression of diabetic retinopathy has not been studied in the Indian population. BACKGROUND: To elucidate the influence of serum lipid control on the incidence and progression of diabetic retinopathy and diabetic macular oedema in subjects with type 2 diabetes. DESIGN: population-based longitudinal observational study in a hospital setting. PARTICIPANTS: 890 subjects were examined at baseline and follow-up METHODS: Diabetic retinopathy was graded per Modified Early Treatment Diabetic Retinopathy Study scales; 45°, 4-field dilated stereoscopic digital photography was performed with an additional 30°, 7-field for those who had retinopathy...
May 17, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28508561/diclofenac-for-pain-associated-with-intravitreal-injections-a-prospective-randomized-placebo-controlled-study
#4
Olga E Makri, Foteini N Tsapardoni, Dionisios D Pagoulatos, Nikolaos Pharmakakis, Constantine D Georgakopoulos
IMPORTANCE: Intravitreal injections (IVI) are often associated with pain. BACKGROUND: To evaluate the analgesic effect of diclofenac in patients undergoing IVI. DESIGN: Single-centre, prospective, randomized, triple-arm, placebo-controlled, interventional study in the University Hospital of Patras. PARTICIPANTS: Seventy-four patients. METHODS: Group 1 (n = 25) received topical diclofenac 45 minutes before IVI, Group 2 (n = 25) received oral diclofenac 4 hours before IVI and topical diclofenac while Group 3 (n = 24) received placebo before IVI...
May 15, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28508415/proptosis-secondary-to-third-nerve-palsy
#5
LETTER
Luke K Chehade, Saul N Rajak, Dinesh Selva
No abstract text is available yet for this article.
May 15, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28494517/exploration-of-peripapillary-vessel-density-in-highly-myopic-eyes-with-peripapillary-intrachoroidal-cavitation-and-its-relationship-with-ocular-parameters-using-optical-coherence-tomography-angiography
#6
Chen Qiuying, He Jiangnan, Hua Yihong, Fan Ying
IMPORTANCE: Identifying changes of peripapillary vessel density in highly myopic eyes with peripapillary intrachoroidal cavitation (PICC) by optical coherence tomography angiography (OCTA). BACKGROUND: To investigate peripapillary vessel density and its relationship with other ocular parameters in highly myopic eyes with PICC. DESIGN: This was a hospital-based, cross-sectional study. PARTICIPANTS: Thirty-five highly myopic eyes with PICC, 46 highly myopic eyes without PICC and 36 normal eyes were included in this study...
May 11, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28488383/pax6-allelic-heterogeneity-in-mexican-congenital-aniridia-patients-expanding-the-mutational-spectrum-with-7-novel-pathogenic-variants
#7
Sofía Pérez-Solórzano, Oscar F Chacón-Camacho, Mirena C Astiazarán, Gerardo Ledesma-Gil, Juan Carlos Zenteno
IMPORTANCE: To describe the clinical characteristics and mutational analysis of Mexican patients with aniridia and PAX6 mutations. BACKGROUND: Aniridia is a panocular hereditary eye disease caused by mutations in the PAX6 transcription factor. Mutation detection rate is highly variable ranging from 30 to 90% in different populations. Very few studies have been published about the PAX6 mutational analysis in aniridia patients from Mexico. In order to establish a more representative PAX6 mutational frequency in the country, a cohort of 22 Mexican unrelated aniridia probands were analyzed in this study...
May 9, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28488341/next-generation-sequencing-targeted-disease-panel-in-rod-cone-retinal-dystrophies-in-m%C3%A4-ori-and-polynesian-reveals-novel-changes-and-a-common-founder-mutation
#8
Andrea L Vincent, Nandoun Abeysekera, Katherine A van Bysterveldt, Verity F Oliver, Jamie M Ellingford, Stephanie Barton, Graeme Cm Black
IMPORTANCE: This study identifies unique genetic variation observed in a cohort of Māori and Polynesian patients with rod-cone retinal dystrophies using a targeted Next Generation Sequencing (NGS) retinal disease gene panel BACKGROUND: With over 250 retinal disease genes identified, genetic diagnosis is still only possible in 60-70% of individuals, and even less within unique ethnic groups. DESIGN: Prospective genetic testing in patients with rod-cone retinal dystrophies identified from the New Zealand Inherited Retinal Disease (IRD) Database, PARTICIPANTS: Sixteen Patients of Māori and Polynesian ancestry...
May 9, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28486785/bilateral-simultaneous-presentation-of-posner-schlossman-syndrome
#9
LETTER
Lauren K Herring, Graham A Lee, Peter Shah
No abstract text is available yet for this article.
May 9, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28486775/anuric-acute-kidney-injury-due-to-low-dose-oral-acetazolamide-with-hypercrystalluria
#10
LETTER
Xiaoxuan Liu, Freda Sii, John Horsburgh, Peter Shah
No abstract text is available yet for this article.
May 9, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28472538/singapore-indian-eye-study-2-methodology-and-impact-of-migration-on-systemic-and-eye-outcomes
#11
Charumathi Sabanayagam, Wanfen Yip, Preeti Gupta, Riswana Bb Mohd Abdul, Ecosse Lamoureux, Neelam Kumari, Gemmy Cm Cheung, Carol Y Cheung, Jie Jin Wang, Ching-Yu Cheng, Tien Yin Wong
IMPORTANCE: Asian Indians are the fastest growing migration groups in the world. Studies evaluating the impact of migration on disease outcomes in this population are rare. BACKGROUND: We describe the methodology of the Singapore Indian Eye Study-2 (SINDI-2) aimed to evaluate the impact of migration status on diabetic retinopathy (DR) and other major age-related eye diseases in Asian Indians living in an urban environment. DESIGN: Population-based cohort study PARTICIPANTS: 2200 adults who participated in baseline SINDI (2007-09, mean age [range] = 57...
May 4, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28467643/yield-of-routine-pre-cataract-surgery-macular-optical-coherence-tomography-in-finding-clinically-undetected-macular-pathology
#12
LETTER
Nicholas J Enright, Andrew Catran, Nayomi Perera, Yen Cheng, Paul Adler
No abstract text is available yet for this article.
May 3, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28464531/meningococcal-w-outbreak-in-victoria-an-atypical-presentation-of-conjunctivitis-in-a-young-adult-in-melbourne-australia
#13
LETTER
Wesley Wh Teoh, Katherine J Walker
No abstract text is available yet for this article.
May 2, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28464476/intravitreal-injection-has-overtaken-cataract-surgery-in-australia
#14
LETTER
Haiying Chen, Wei Wang, Mingguang He
No abstract text is available yet for this article.
May 2, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28436565/self-retaining-weighted-thermoplastic-ampoule-holder-for-aflibercept-and-ranibizumab-vials
#15
LETTER
WengOnn Chan, Melissa Shields, Paul Sia, Robert Casson
No abstract text is available yet for this article.
April 24, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28432717/depressive-symptoms-in-older-adults-awaiting-cataract-surgery-methodological-and-statistical-issues
#16
LETTER
Saeid Safiri, Erfan Ayubi
No abstract text is available yet for this article.
April 21, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28430392/depressive-symptoms-in-older-adults-awaiting-cataract-surgery-methodological-and-statistical-issues-response
#17
LETTER
Anna Palagyi, Lisa Keay, Kris Rogers
No abstract text is available yet for this article.
April 21, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28421664/intermediate-and-long-term-outcome-of-piggyback-drainage-connecting-glaucoma-drainage-device-to-a-device-in-situ-for-improved-intraocular-pressure-control
#18
Edward Dervan, Edward Lee, Antonio Giubilato, Tina Khanam, Panayiotis Maghsoudlou, William H Morgan
IMPORTANCE: This study provides results of a treatment option for patients with failed primary glaucoma drainage device BACKGROUND: To describe and evaluate the long term intraocular pressure (IOP) control and complications of a new technique joining a second glaucoma drainage device (GDD) directly to an existing GDD: termed "piggyback drainage". DESIGN: A retrospective, interventional cohort study PARTICIPANTS: 18 eyes of 17 patients who underwent piggyback drainage between 2004 and 2013 inclusive...
April 19, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28421654/short-term-outcomes-of-small-incision-cataract-surgery-provided-by-a-regional-population-in-the-pacific
#19
Riyaz Bhikoo, Hans Vellara, Salome Lolokabaira, Neil Murray, Biu Sikivou, Charles McGhee
BACKGROUND: This study aims to describe patient demographics, visual and surgical outcomes of a cohort undergoing small incision cataract surgery at a Pacific regional ophthalmic training facility. DESIGN: This is a prospective, longitudinal study conducted at the Pacific Eye Institute, Fiji. PARTICIPANTS: One hundred fifty-six patients underwent small incision cataract surgery. METHODS: Preoperatively, a complete ophthalmic examination, including pachymetry and macular optical coherence tomography performed by two independent investigators...
April 19, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28418609/real-time-measurement-of-needle-forces-and-acute-pressure-changes-during-intravitreal-injections
#20
Logan Christensen, Ashlee Cerda, Jeffrey L Olson
BACKGROUND: The purpose of this study was to use a physiological pressure transducer to measure real-time, continuous pressure changes in an ex-vivo study model of porcine eyes to record the amount of force needed for scleral penetration and to measure acute IOP rise during intravitreal injections. METHODS: A pressure transducer was inserted into the anterior chamber of 30 fresh porcine eyes and intraocular pressure was measured two seconds prior to intravitreal injection until two seconds after...
April 18, 2017: Clinical & Experimental Ophthalmology
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