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American Journal of Clinical Dermatology

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https://www.readbyqxmd.com/read/27913962/bathing-and-associated-treatments-in-atopic-dermatitis
#1
REVIEW
Julia K Gittler, Jason F Wang, Seth J Orlow
Atopic dermatitis is one of the most common complaints presenting to dermatologists, and patients typically inquire as to appropriate bathing recommendations. Although many dermatologists, allergists, and primary-care practitioners provide explicit bathing instructions, recommendations regarding frequency of bathing, duration of bathing, and timing related to emollient and medication application relative to bathing vary widely. Conflicting and vague guidelines stem from knowledge related to the disparate effects of water on skin, as well as a dearth of studies, especially randomized controlled trials, evaluating the effects of water and bathing on the skin of patients with atopic dermatitis...
December 3, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27878477/paraneoplastic-pemphigus-and-autoimmune-blistering-diseases-associated-with-neoplasm-characteristics-diagnosis-associated-neoplasms-proposed-pathogenesis-treatment
#2
REVIEW
Saritha Kartan, Vivian Y Shi, Ashley K Clark, Lawrence S Chan
Autoimmune paraneoplastic and neoplasm-associated skin syndromes are characterized by autoimmune-mediated cutaneous lesions in the presence of a neoplasm. The identification of these syndromes provides information about the underlying tumor, systemic symptoms, and debilitating complications. The recognition of these syndromes is particularly helpful in cases of skin lesions presenting as the first sign of the malignancy, and the underlying malignancy can be treated in a timely manner. Autoimmune paraneoplastic and neoplasm-associated bullous skin syndromes are characterized by blister formation due to an autoimmune response to components of the epidermis or basement membrane in the context of a neoplasm...
November 22, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27854065/the-utility-of-text-message-reminders-for-acne-patients-a-pilot-study
#3
Jean-Phillip Okhovat, Francesca Tenconi, Jenny Kim, Christina N Kim
BACKGROUND: Acne vulgaris is one of the three most common cutaneous disorders, affecting approximately 50 million people in the US and many more throughout the world. OBJECTIVE: We designed a pilot program to explore how patients may interact with cell phone technology to supplement medical care beyond patient reminders that would encompass education, interaction, and data capturing. METHODS: Twenty-four patients completed a 3-month study in which participants received daily text message reminders for the first 2 weeks of the study, then once weekly thereafter, to take their oral medication or apply topical therapy either once or twice daily...
November 16, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27826815/is-there-a-role-for-opportunistic-infection-prophylaxis-in-pemphigus-an-expert-survey
#4
Yael A Leshem, Igor Snast, Rivka Friedland, Lihi Atzmony, Assi Levi, Emmilia Hodak, Daniel Mimouni
BACKGROUND: Opportunistic infections (OIs) are a dreaded adverse effect of immunosuppressive therapy, leading to the use of opportunistic infection prophylaxis (OIP) in many immunosuppressed conditions. However, guidelines for OIP in pemphigus are lacking. OBJECTIVE: Our objective was to evaluate the approach of leading pemphigus experts towards OIP. METHODS: We conducted an online survey of OIP trends. RESULTS: The survey was completed by 33 experts...
November 8, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27804089/topical-treatment-of-facial-seborrheic-dermatitis-a-systematic-review
#5
REVIEW
Aditya K Gupta, Sarah G Versteeg
BACKGROUND: Facial seborrheic dermatitis (SD), a chronic inflammatory skin condition, can impact quality of life, and relapses can be frequent. Three broad categories of agents are used to treat SD: antifungal agents, keratolytics, and corticosteroids. Topical therapies are the first line of defense in treating this condition. OBJECTIVE: Our objective was to critically review the published literature on topical treatments for facial SD. METHODS: We searched PubMed, Scopus, Clinicaltrials...
November 2, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27770310/treating-alopecia-areata-current-practices-versus-new-directions
#6
Aditya K Gupta, Jessie Carviel, William Abramovits
Alopecia areata (AA) is non-scarring hair loss resulting from an autoimmune disorder. Severity varies from patchy hair loss that often spontaneously resolves to severe and chronic cases that can progress to total loss of scalp and body hair. Many treatments are available; however, the efficacy of these treatments has not been confirmed, especially in severe cases, and relapse rates are high. First-line treatment often includes corticosteroids such as intralesional or topical steroids for mild cases and systemic steroids or topical immunotherapy with diphenylcyclopropenone or squaric acid dibutylester in severe cases...
October 22, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27734332/cryofibrinogenemia-induced-cutaneous-ulcers-a-review-and-diagnostic-criteria
#7
Ayman Grada, Vincent Falanga
Chronic skin ulcers are frequently encountered in clinical practice and are often due to very heterogeneous etiologies. Cryofibrinogenemia is an unusual cause of non-healing skin ulcers. It is a small-vessel occlusive vascular disorder that results from the precipitation of cryofibrinogens in plasma. The lack of definitive diagnostic criteria means cryofibrinogenemia remains an under-diagnosed entity that causes significant morbidity. One of the most common manifestations of cryofibrinogenemia is skin ulceration...
October 12, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27722955/laser-tattoo-removal-an-update
#8
Lina I Naga, Tina S Alster
Tattoo art has been around for thousands of years in every culture and is currently flourishing in all age groups, social classes, and occupations. Despite the rising popularity of tattoos, demand for their removal has also increased. While various treatments, including surgical excision, dermabrasion, and chemical destruction have historically been applied, over the past 2 decades, lasers have revolutionized the way tattoos are treated and have become the gold standard of treatment. To achieve optimal cosmetic outcome of treatment, lasers emitting high energies and short pulses are required to adequately destroy tattoo ink...
October 8, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27696147/relapsing-polychondritis-a-review-and-guide-for-the-dermatologist
#9
AnneLiese Smylie, Neel Malhotra, Alain Brassard
Relapsing polychondritis, or RP, is a rare connective tissue disease characterized by relapsing-remitting destructive inflammation of the cartilaginous and other proteoglycan-rich structures in the body. Given the relatively low incidence of RP, a concise clinically relevant guide, focusing on the cutaneous manifestations of this serious disease, is lacking. In this review, we provide the dermatologist with an approach to diagnosing RP and a guide to its initial work-up, and management. We close with an overview of the currently available treatment modalities for RP...
October 1, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27650520/managing-scalp-psoriasis-an-evidence-based-review
#10
Ting-Shun Wang, Tsen-Fang Tsai
BACKGROUND: Scalp psoriasis is commonly the initial presentation of psoriasis, and almost 80 % of patients with psoriasis will eventually experience it. OBJECTIVE: Although several systematic reviews and guidelines exist, an up-to-date evidence-based review including more recent progress on the use of biologics and new oral small molecules was timely. METHODS: Of the 475 studies initially retrieved from PubMed and the 845 from Embase (up to May 2016), this review includes 27 clinical trials, four papers reporting pooled analyses of other clinical trials, ten open-label trials, one case series, and two case reports after excluding non-English literature...
September 21, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27826816/acknowledgement-to-referees
#11
(no author information available yet)
No abstract text is available yet for this article.
December 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27815915/body-region-involvement-and-quality-of-life-in-psoriasis-analysis-of-a-randomized-controlled-trial-of-adalimumab
#12
April W Armstrong, Delfina Guadalupe Villanueva Quintero, Cristina M Echeverría, Yihua Gu, Mahinda Karunaratne, Ofelia Reyes Servín
BACKGROUND: Psoriasis severity and treatment responsiveness vary by body region, which differentially impacts quality of life (QoL). OBJECTIVE: The objective of the study was to examine adalimumab efficacy by body region and regional response and QoL relationship. METHODS: Patients (n = 1212) with moderate-to-severe psoriasis were randomized 2:1 to 80 mg at week 0, followed by adalimumab 40 mg or placebo every other week for 16 weeks in the double-blind REVEAL study...
December 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27785707/medical-malpractice-in-dermatology-part-ii-%C3%A2-what-to-do-once-you-have-been-served-with-a-lawsuit
#13
Vidhi V Shah, Marshall B Kapp, Stephen E Wolverton
Facing a malpractice lawsuit can be a daunting and traumatic experience for healthcare practitioners, with most clinicians naïve to the legal landscape. It is crucial for physicians to know and understand the malpractice system and his or her role once challenged with litigation. We present part II of a two-part series addressing the most common medicolegal questions that cause a great deal of anxiety. Part I focused upon risk-management strategies and prevention of malpractice lawsuits, whereas part II provides helpful suggestions and guidance for the physician who has been served with a lawsuit complaint...
December 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27785706/deoxycholic-acid-a-review-in-submental-fat-contouring
#14
Emma D Deeks
Deoxycholic acid is a secondary bile acid involved in dietary fat emulsification/solubilization that causes adipocyte lysis when injected into subcutaneous fat tissue. A 10 mg/mL injectable solution of synthetic deoxycholic acid (Kybella™; Belkyra™) is indicated in various countries, including the USA and several within Europe/the EU, to improve the appearance of moderate to severe convexity or fullness associated with submental fat (SMF) in adults, where it is currently the only approved treatment for fat below the chin...
December 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27734331/medical-malpractice-in-dermatology-part-i-reducing-the-risks-of-a-lawsuit
#15
Vidhi V Shah, Marshall B Kapp, Stephen E Wolverton
Malpractice risk is a common source of concern for the practicing physician. Dermatologists experience fewer lawsuits than most other specialists in medicine, but the risk is not negligible. All physicians should familiarize themselves with areas of potential risk and avoid medico-legal pitfalls. We present Part I of a two-part series addressing medico-legal questions common to most practitioners that cause a great deal of anxiety. Part I will focus upon risk management and prevention of future malpractice lawsuits, and Part II deals with suggestions and guidance once a lawsuit occurs...
December 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27696143/erratum-to-shiitake-mushroom-dermatitis-a-review
#16
Matthew Paul Stephany, Stella Chung, Marc Zachary Handler, Nancy Stefanie Handler, Glenn A Handler, Robert A Schwartz
No abstract text is available yet for this article.
December 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27665299/primary-and-secondary-chemoprevention-of-malignant-melanoma
#17
REVIEW
Jessica Mounessa, Talayesa Buntinx-Krieg, Rosie Qin, Cory A Dunnick, Robert P Dellavalle
The incidence of malignant melanoma (MM) continues to rise in the United States. While sun protection and full body skin examinations remain the mainstay of preventative care, chemoprevention of the deadly disease has become an increasingly popular field of study. In this focused review, we discuss current findings and analyze the risks and benefits of various agents investigated for the primary and secondary chemoprevention of MM. Such agents include topical retinoids, vitamins, and supplements, Polypodium leucotomas extracts, non-steroidal anti-inflammatory agents (NSAIDs), statins, sunscreens, and field therapy with topical imiquimod for primary and secondary chemoprevention...
December 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27637620/drug-induced-tactile-hallucinations-beyond-recreational-drugs
#18
REVIEW
Mio Nakamura, John Koo
In monosymptomatic hypochondriacal psychosis (MHP), such as delusional infestation (DI), the patient has a fixed, false, encapsulated belief associated with tactile hallucinations (TH), most commonly formication, which is defined as cutaneous sensations of crawling, stinging, biting, etc., without evidence of infestation. Drug-induced TH should be considered in patients with suspected MHP. Although recreational drugs such as cocaine, amphetamines, and narcotics are well known to induce TH, many busy practicing dermatologists may not be familiar with other types of medications that can induce TH...
December 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27591889/exercise-induced-vasculitis-a-review-with-illustrated-cases
#19
REVIEW
Olivier Espitia, Brigitte Dréno, Elisabeth Cassagnau, Quentin Didier, Thibaut Quillard, Christelle Nicol, Yann Le Bouch, Bernard Planchon, Marc-Antoine Pistorius
Although exercise-induced vasculitis (EIV) is usually misdiagnosed, it is not uncommon. Occurring mostly after prolonged exercise, especially in hot weather, EIV is an isolated cutaneous vasculitis with stereotypical presentation. This article reviews the clinical characteristics, treatments, and outcomes of EIV based on the published literature. We report 99 patients who developed EIV after walking, dancing, swimming, or hiking especially during hot weather, including the records of 16 patients with EIV treated at our hospital from 2007 to 2015...
December 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27517368/itch-in-the-general-internal-medicine-setting-a-cross-sectional-study-of-prevalence-and-quality-of-life-effects
#20
Jonathan I Silverberg, Keiki Hinami, William E Trick, David Cella
BACKGROUND: Itch is a well-established symptom in cutaneous disease. However, little is known about the burden of itch outside the dermatology setting. PURPOSE: To determine the prevalence and impact of itch on quality of life (QOL) in the general internal medicine setting. METHODS: We performed a cross-sectional study of 2076 adults from an outpatient general internal medicine clinic, using an audio computer-assisted self-administered interview...
December 2016: American Journal of Clinical Dermatology
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