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Japanese Journal of Infectious Diseases

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https://www.readbyqxmd.com/read/28367888/the-first-isolation-of-zika-virus-from-a-japanese-patient-who-returned-to-japan-from-fiji-in-2016
#1
Masakatsu Taira, Tomoko Ogawa, Haruna Nishijima, Kojiro Yamamoto, Chiemi Hotta, Mamiko Akita, Shigeru Tajima, Masayuki Saijo
Outbreaks of Zika virus (ZIKV) infection in tropical and subtropical regions are cause of worldwide concern and represents a public health emergency. ZIKV was isolated from a 17-year-old patient with fever and maculopapular rash. The patient returned to Japan from the Republic of Fiji in late April 2016. The complete genome sequence of the ZIKV isolate, ZIKV/Hu/S36/Chiba/2016, which might be the first strain to be isolated in Japan, was determined and reported.
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367887/antimicrobial-resistance-of-pseudomonas-aeruginosa-isolated-from-dogs-and-cats-in-primary-veterinary-hospitals-in-japan
#2
Shoichiro Yukawa, Yuzo Tsuyuki, Tomomi Sato, Akira Fukuda, Masaru Usui, Yutaka Tamura
To investigate antimicrobial resistance, 200 Pseudomonas aeruginosa isolates were collected from dogs and cats in primary veterinary hospitals in Japan. Resistance rates against ciprofloxacin, cefotaxime, gentamicin, amikacin, and fosfomycin were 9, 12.5, 4.5, 2.5, and 35.5%, respectively. One strain (0.5%) displayed resistance to ceftazidime. We did not detect any strain resistant to imipenem nor any multidrug-resistant P. aeruginosa as defined by the Law Concerning the Prevention of Infections and Medical Care for Patients with Infections of the Japanese Ministry of Health, Labour, and Welfare...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367886/changes-in-serum-iga-antibody-levels-against-the-glycopeptidolipid-core-antigen-during-antibiotic-treatment-of-mycobacterium-avium-complex-lung-disease
#3
Byung Woo Jhun, Su-Young Kim, Hye Yun Park, Kyeongman Jeon, Sung Jae Shin, Won-Jung Koh
We evaluated serial changes in the levels of serum immunoglobulin A (IgA) antibody to the glycopeptidolipid (GPL) core antigen during antibiotic treatment in 57 patients with M. avium complex (MAC) lung disease, at baseline (T0) and after 3 months (T3) and 6 months (T6) of treatment. The median patient age was 59 years and 37 (65%) were female. Etiologic organisms included M. avium in 32 (56%) patients and M. intracellulare in 25 (44%). Seven (12%) patients had the fibrocavitary form of the disease on computed tomography...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367885/antimicrobial-susceptibility-surveillance-of-neisseria-gonorrhoeae-isolates-in-changsha-china-during-2003-2015
#4
Ting Peng, Hui Lin, Qinglin Liu, Jiajin Yang, Wei Cao, Hui Ding, Lingli Tang
A total of 1294 Neisseria gonorrhoeae isolates obtained in Changsha, China from 2003 to 2015 were examed for susceptibility to penicillin, ciprofloxacin, spectinomycin and ceftriaxone by disc diffusion method and the ceftriaxone MICs of 460 isolates during 2008-2015 were determined by agar dilution method and the ceftriaxone intermediate susceptible isolates were tested for azithromycin susceptibility in addition. The results exhibited that the resistant rate to penicillin and ciprofloxacin were 77.5% and 94...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367884/prevalence-of-diarrheagenic-escherichia-coli-in-foods-and-fecal-specimens-obtained-from-cattle-pigs-chickens-asymptomatic-carriers-and-patients-in-osaka-and-hyogo-japan
#5
Lili Wang, Shaobo Zhang, Dongming Zheng, Sami Fujihara, Akiyo Wakabayashi, Kazuyuki Okahata, Masakazu Suzuki, Atsunori Saeki, Hiromi Nakamura, Yukiko Hara-Kudo, Eriko Kage-Nakadai, Yoshikazu Nishikawa
The source and routes of diarrheagenic Escherichia coli (DEC) remain poorly clarified. To investigate the involvement of domestic animals in the dissemination of DEC, the prevalence of DEC among foods and fecal specimens of cattle, pigs, chickens, healthy carriers, and patients in Osaka and Hyogo, Japan, was investigated using a multiplex real-time PCR assay. The most prevalent virulence genes were astA and eae, with prevalences of 46.8% and 27.4%, respectively. stx1 (26.6%) and stx2 (45.9%) were prevalent in cattle feces, and est (8...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367883/quantiferon-%C3%A2-tb-gold-in-tube-test-for-tuberculosis-prevention-in-hiv-infected-patients
#6
Thana Khawcharoenporn, Benjawan Phetsuksiri, Janisara Rudeeaneksin, Sopa Srisungngam, Anucha Apisarnthanarak
Optimal testing strategy for diagnosing latent tuberculosis infection and guiding isoniazid preventive therapy (IPT) is uncertain among HIV-infected patients. A 4-year prospective study was conducted among Thai HIV-infected patients who underwent simultaneous tuberculin skin test (TST) and QuantiFERON®-TB Gold In-tube Test (QFT-IT) at care entry. Based on baseline test results, patients were categorized into 4 groups: 1) QFT-IT-positive, TST-reactive 2) QFT-IT-positive, TST-non-reactive 3) QFT-IT-negative, TST-reactive, or 4) QFT-IT-negative, TST-non-reactive...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367882/severe-acute-respiratory-infection-sari-surveillance-for-hospitalized-patients-in-northern-vietnam-2011-2014
#7
Hang Khanh Le Nguyen, Son Vu Nguyen, Anh Phuong Nguyen, Phuong Mai Vu Hoang, Thanh Thi Le, Thach Co Nguyen, Huong Thu Hoang, Cuong Duc Vuong, Loan Thi Thanh Tran, Le Quynh Mai
Worldwide Severe Acute Respiratory Infections (SARI) are leading causes of hospitalization, morbidity and mortality in children. The aim of this study was to identify viral pathogens responsible for SARI in northern Vietnam from 2011 to 2014. METHODS: Throat swabs and tracheal aspirates were collected from SARI patients according to WHO Guidelines. Thirteen different viral pathogens (Influenza A(H1N)pdm09; A/H3N2; A/H5; A/H7 and B; Para influenza 1,2,3; RSV; HMPV; Adeno; SARS-CoV and Rhino) were tested by conventional/ real-time RT-PCR...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367881/epidemiological-characteristics-and-clinical-treatment-outcome-of-typhoid-fever-in-ningbo-china-2005-2014-pfge-results-revealing-great-proportion-of-common-transmission-sources
#8
Qifa Song, Yuanbin Yang, Wenping Lin, Bo Yi, Guozhang Xu
We aimed to describe the molecular epidemiological characteristics and clinical treatment outcome of typhoid fever in Ningbo, China, 2005-2014. Eighty-eight Salmonella Typhi isolates were obtained from 307 admitted patients. Three prevalent pulsed-field gel electrophoresis (PFGE) patterns of 54 isolates in 3 outbreaks were identified. Overall, there were 64 (72.7%) isolates from cases in clusters and 24 (27.3%) isolates from sporadic cases. Resistance to nalidixic acid (n=47; 53.4%) and ampicillin (n=40; 45...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367880/predation-efficacy-of-bdellovibrio-bacteriovorus-on-multidrug-resistant-clinical-pathogens-and-their-corresponding-biofilms
#9
Yao Sun, Jianzhong Ye, Yuanbo Hou, Huale Chen, Jianming Cao, Tieli Zhou
The aim of the present study was to evaluate the predation efficacy of Bdellovibrio bacteriovorus on multidrug-resistant (MDR) or extensive drug resistant (XDR) gram-negative pathogens and their corresponding biofilms. In this study, we examined the ability of B. bacteriovorus to prey on MDR and XDR gram-negative clinical bacteria, including Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii. Results showed that B. bacteriovorus was able to prey on all planktonic cultures, among which the most efficient predation was found for drug-resistant E...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367879/phenotypic-and-molecular-characterization-of-enteroaggregative-escherichia-coli-isolated-in-kawasaki-japan
#10
Akiko Kubomura, Takako Misaki, Sachiko Homma, Chiaki Matsuo, Nobuhiko Okabe
Enteroaggregative Escherichia coli (EAEC), an enteric pathogen, causes persistent diarrhea in children, HIV-infected individuals, and travelers in economically developing countries. However, the pathogenesis of EAEC infection is not well understood. The aim of this study is to characterize EAEC in Japan. During 2012-2014, we identified 40 EAEC strains carrying the aggR gene at the Kawasaki City Institute for Public Health, Japan. We characterized these strains using O:H-antigen typing, polymerase chain reaction (for pCVD432, astA, extended-spectrum beta-lactamase, and four aggregative adherence fimbriae genes), HEp-2 cell adherence, clump formation, and antimicrobial susceptibility testing...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367878/dengue-immune-humans-have-higher-levels-of-complement-independent-enhancing-antibody-than-complement-dependent-neutralizing-antibody
#11
Atsushi Yamanaka, Eiji Konishi
Dengue is the most important arboviral disease worldwide. We previously reported that most dengue-immune inhabitants in endemic countries have infection-enhancing antibodies whose in vitro activity does not decrease in the presence of complement: that is, complement-independent enhancing antibodies (CiEAb). Here, we compared levels of CiEAb and complement-dependent neutralizing antibodies (CdNAb) in dengue-immune humans. A typical antibody dose-response pattern obtained in our assay system to measure the neutralizing/enhancing antibody balance showed both neutralizing and enhancing activities depending on serum dilution factor...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367877/minocycline-inhibits-the-candida-albicans-budded-to-hyphal-form-transition-and-biofilm-formation
#12
Sanae Kurakado, Kazuhiko Takatori, Takashi Sugita
Candida albicans frequently causes bloodstream infections; the budded-to-hyphal-form transition (BHT) and biofilm formation are major contributors to virulence. In a survey of antibacterial compounds that inhibit C. albicans BHT, we found that the tetracycline derivative minocycline inhibited BHT and subsequent biofilm formation. Minocycline downregulates expression of the hypha-specific genes HWP1 and ECE1, and the adhesion factor gene ALS3 of C. albicans. In addition, minocycline decreases cell surface hydrophobicity and the extracellular β-glucan level in biofilms...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367876/serotype-replacement-in-adult-pneumococcal-pneumonia-after-the-introduction-of-seven-valent-pneumococcal-conjugate-vaccines-for-children-in-japan-a-systematic-literature-review-and-pooled-data-analysis
#13
Shungo Katoh, Motoi Suzuki, Koya Ariyoshi, Konosuke Morimoto
Streptococcus pneumoniae is a major causative agent of adult pneumonia. Following the introduction of pneumococcal conjugate vaccines (PCV) for children, serotype replacement has been reported in adult invasive pneumococcal diseases, but it has not been well-studied for adult pneumococcal pneumonia cases in Asia. To investigate serotype replacement in adult pneumococcal pneumonia in Japan, we conducted a systematic literature search across five databases using terms including pneumococcus, serotype, and their synonyms and derivatives...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28367875/laboratory-and-molecular-characterization-of-dengue-virus-during-the-2014-outbreak-in-guangfo-region-southern-china
#14
Zhao-Fan Luo, Bo Hu, Feng-Yi Zhang, Xiang-Hua Lin, Xiao-Ying Xie, Kun-Yi Pan, Hong-Yu Li, Rui-Wen Ren, Wen-Zhong Zhao
Non-specific symptoms and low viremia levels make early diagnosis of dengue virus (DENV) infection challenging. This study aimed to 1) identify laboratory markers which can predict a positive laboratory diagnosis, and 2) perform a molecular characterization of DENV from the 2014 Guangdong epidemic. This retrospective study enrolled 1044 patients from the Guangdong epidemic who had clinically suspected dengue. Viral RNA was detected by real-time RT-PCR and viral-specific NS1 antigen was detected using ELISA...
March 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28250265/peripheral-blood-plasmacytosis-in-severe-fever-with-thrombocytopenia-syndrome
#15
Taizo Wada, Yasunori Iwata, Yasutaka Kamikawa, Takashi Wada, Akihiro Yachie
No abstract text is available yet for this article.
February 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28250264/methicillin-susceptible-teicoplanin-resistant-staphylococcus-haemolyticus-from-bloodstream-infection-novel-mutation-in-teicoplanin-resistant-operon-tcarab
#16
Yamuna Devi Bakthavatchalam, Thambu David Sudarsanam, Priyanka Babu, Elakkiya Munuswamy, Dhiviya Prabaa Muthuirulandi Sethuvel, Naveen Kumar Devanga Ragupathi, Balaji Veeraraghavan
Staphylococcus haemolyticus is the frequently isolated coagulase-negative staphylococci (CoNS) from blood culture. Here we port a case of methicillin-susceptible S. haemolyticus resistant to teicoplanin and heteroresistant to vancomycin. The isolate was found to susceptible to cefoxitin and resistant to teicoplanin in E-test. PAP-AUC analysis confirmed the presence of vancomycin heteroresistant subpopulation. NGS analysis of the genome revealed the presence of blaZ, msr(A) codes for cross-resistance of macrolide, lincosamide and streptogramin B and quinolone resistance encoding norA gene...
February 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28250263/lambda-interferons-inhibit-herpes-simplex-virus-type-2-replication-in-human-cervical-epithelial-cells-through-activation-of-jak-stat-pathway
#17
Zhu Li, Xuan Lu, Yufan Zhu, Pengfei Cheng, Shi Liu, Yi Zhang, Jingfeng Tang, Sijun Yang, Li Zhou
Herpes Simplex Virus Type 2 (HSV-2) is associated with a variety of diseases, resulting in world-wide health problems. Our early study showed that lambda-interferons (IFN-λs) induced by activation of the toll-like receptors 3/ retinoic acid-inducible protein I (TLR3/RIG-I) signaling pathways contribute to inhibition of HSV-2 replication in the human cervical epithelial cells. However, anti-HSV-2 mechanisms and specific differences in signaling transduction by different IFN-λs in human cervical epithelial cells are unclear...
February 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28250262/increased-irisin-concentrations-in-patients-with-crimean-congo-hemorragic-fever
#18
Seyit Ali Büyüktuna, Halef Okan Doğan, Deniz Bakır, Serpil Erşan, Derya Koç, Sevtap Bakır
Crimean-Congo Hemorrhagic Fever (CCHF) is a life-threatening viral infection. The pathogenesis of the disease is not well understood. The aim of this study was to determine the change in irisin concentrations in patients with CCHF. The study included a total of 30 patients with CCHF and 30 control subjects. Irisin concentrations were determined using a commercial ELISA kit. Median irisin concentrations were 9.03 (5.81-12.22) µg/mL and 4,.2 (3.39-7.62) µg/mL , respectively. There was no correlation between irisin and disease severity...
February 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28250261/high-prevalence-of-campylobacter-ureolyticus-in-stool-specimens-of-children-with-diarrhea-in-japan
#19
Noritoshi Hatanaka, Akinori Shimizu, Srinuan Somroop, Yiming Li, Masahiro Asakura, Akira Nagita, Sharda Prasad Awasthi, Atsushi Hinenoya, Shinji Yamasaki
Campylobacter ureolyticus has been considered as a potential pathogenic bacterium. In this study, a total 586 stool samples were collected from 0-12 year-old children with diarrhea between November 2013 and April 2015 and examined with microbiological tests in the hospital for diagnosis of common enteric pathogens including C. jejuni and C. coli. Then in our laboratory, these samples were analyzed by 16S rRNA sequence-based Campylobacter genus-specific PCR (C16S PCR) and 283 (48.3%) samples show positive with this PCR assay...
February 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28250260/burden-of-rotavirus-and-enteric-bacterial-pathogens-among-children-under-five-years-old-hospitalized-with-diarrhea-in-suburban-and-rural-areas-in-kenya
#20
Mohammad Shah, Erick Odoyo, Ernest Wandera, Cyrus Kathiiko, Martin Bundi, Gabriel Miringu, Sora Guyo, Satoshi Komoto, James Nyangao, Mohamed Karama, Takao Tsuji, Koki Taniguchi, Kouichi Morita, Yoshio Ichinose
This study aimed to investigate the incidence of rotavirus and enteric bacterial infections among children up to five years old with diarrhea living in suburban and rural areas in Kenya. It was a cross-sectional descriptive study, and a total of 1060 diarrheal fecal specimens were obtained from 722 children at the Kiambu County Hospital (KCH) located in a suburban area and 338 children from the Mbita District Hospital (MDH) located in a rural part of western Kenya, between August 2011 and December 2013. Of the 1060 isolates, group A rotavirus (RVA) was detected in 29...
February 28, 2017: Japanese Journal of Infectious Diseases
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