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Japanese Journal of Infectious Diseases

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https://www.readbyqxmd.com/read/29709992/characterization-of-virucidal-activities-of-chlorous-acid
#1
Hisataka Goda, Keiko Ikeda, Mitsunori Nishide, Tamiko Nagao, A Hajime Koyama
Virucidal effects of chlorous acid on enveloped and non-enveloped viruses were characterized. The virucidal activity was prominent against the enveloped viruses. However, some viruses among non-enveloped viruses, such as human rhinovirus and feline calicivirus, showed significant sensitivity to the reagent while the other, poliovirus and coxsackievirus, showed weak sensitivity, suggesting the presence of two classes of sensitivity among non-enveloped viruses against the reagent. In addition, characterization of the mode of inactivation by the reagent revealed that this inactivation of virus is strongly dependent on virus species, contaminated proteins and composition of solvent system...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709991/population-size-dependency-of-measles-epidemic-that-was-scalable-from-japanese-prefectures-to-european-countries
#2
Hiroshi Yoshikura
Relation between number of measles patients (y) and population size (x) was expressed by an equation y = axs , where a is a constant and s the slope of the plot; s was 2.04-2.17 for prefectures in Japan, i.e., the number of patients was proportional to square of the prefecture population size. For European countries that joined European Union no later than 2009, the slope was 1.43-1.87. The measles' population dependency found among prefectures in Japan was thus scalable up to European countries. It was surprising because, unlike Japan, population density in EU countries was not uniform and not proportional to the population size...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709990/human-parechovirus-infection-in-children-in-taiwan-a-retrospective-single-hospital-study
#3
Jenn-Tzong Chang, Yao-Shen Chen, Bao-Chen Chen, Tsi-Shu Huang, Tsung-Hsien Chang
To understand human parechovirus (HPeV) infections in Taiwanese children, we analyzed data for 112 children (age ≤ 10 years) with HPeV infection diagnosed from July 2007 to June 2016 in a medical centre in Kaohsiung, southern Taiwan. Infection was with HPeV1 (n=94), HPeV3 (n=3), HPeV4 (n=3), HPeV6 (n=1) and non-typeable HPeV (n=11). We compared the clinical implication for children younger than 3 months (n=56) and 3 months and older (n=31), excluding the 25 children with concomitant infection. Fever was noted in almost half of the children younger than 3 months but was more frequent in older than younger children (83...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709989/congenital-cytomegalovirus-pneumonitis-and-treatment-response-evaluation-using-viral-load-during-ganciclovir-therapy-a-case-report
#4
Minsoo Lee, Keiji Goishi, Yuka Torii, Yoshinori Ito, Hiroya Ono, Tomoko Mori, Naoyuki Kashiwa, Shinichi Hosokawa, Hiroyuki Shichino
Cytomegalovirus (CMV) is the most common cause of congenital infection. Pneumonitis is considered to be a rare manifestation although congenital CMV infection presents with various non-specific findings. Ganciclovir and valganciclovir are beneficial for improving neurodevelopmental sequelae and hearing outcome of congenital CMV infection, but treatment response evaluationis not well reported. We report a female case of congenital CMV infectionpresenting with pneumonitis, meningoencephalitis, and chorioretinitis...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709988/first-molecular-detection-and-phylogenetic-analysis-of-anaplasma-phagocytophilum-from-a-clinical-case-of-canine-granulocytic-anaplasmosis-in-japan
#5
Yuichi Fukui, Seigo Ohkawa, Hisashi Inokuma
Anaplasma phagocytophilum DNA was detected from a dog with canine granulocytic anaplasmosis (CGA) in Japan. Phylogenetic analysis of the DNA using 16s rRNA, gltA, and groEL sequences revealed that the strain was nearly identical to A. phagocytophilum detected from Apodemus agrarius (black-striped field mouse) in China and Korea. This report is the first phylogenetic study on A. phagocytophilum from a CGA case in Japan.
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709987/administrative-laboratory-findings-for-highly-pathogenic-avian-influenza-virus-a-h5n6-in-individuals-engaged-in-a-mass-culling-of-poultry-hokkaido-japan-2016
#6
Masahiro Miyoshi, Rika Komagome, Hiroki Yamaguchi, Setsuko Ishida, Hideki Nagano, Asami Ohnishi, Masayuki Kikuchi, Kazuyo Hamaya, Kohei Shimada, Masataka Fukami, Hajime Shimada, Tsukasa Ohara, Motohiko Okano
No abstract text is available yet for this article.
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709986/emergence-of-new-recombinant-noroviruses-gii-p16-gii-2-and-gii-p16-gii-4-in-aichi-japan-during-the-2016-17-season
#7
Mami Hata, Noriko Nakamura, Shinichi Kobayashi, Ayano Onouchi, Tomochika Saito, Emi Hirose, Hirokazu Adachi, Noriko Saito, Miyabi Ito, Yoshihiro Yasui, Masakado Matsumoto, Hiroko Minagawa
No abstract text is available yet for this article.
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709985/the-use-of-electric-toilet-seats-with-water-spray-is-efficacious-in-maintaining-hand-hygiene-in-experimental-model
#8
Shigeharu Oie, Hiromi Aoshika, Emiko Arita, Akira Kamiya
A simulatory experiment was conducted to examine the hand contamination from wiping the buttocks after using or not using an electric toilet seat with water spray. A model of the buttocks was smeared with diarrheal feces artificially made containing Serratia marcescens, and wiped by the participants wearing plastic gloves with 4 sheets of toilet paper using the water spray of electric seat or not. Subsequently, the presence of S. marcescens on the surfaces of the gloves were quantitated. The mean count ± standard deviation of S...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709984/the-protobothrops-flavoviridis-hemorrhagic-metalloproteinase-hr2-is-inhibited-by-human-alpha-2-macroglobulin
#9
Nobuya Morine, Seiko Matsuda, Yumiko Izumi, Akiko Oshiro, Jun Kudaka
Habu (Protobothrops flavoviridis) venom toxoid vaccination was performed in individuals living in Amami-oshima from 1965 to 2002, the effectiveness of which was investigated in 1991. The results raised the possibility that normal human serum inherently contains an inhibitor of the hemorrhagic metalloproteinase HR2, considered to be one of the major components of habu venom. In this study, we investigated the interaction between the hemorrhagic metalloproteinases HR1 and HR2 from habu venom and human α2-macroglobulin...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709983/low-seroprevalence-of-severe-fever-with-thrombocytopenia-syndrome-virus-antibodies-in-individuals-living-in-an-endemic-area-of-japan
#10
Mutsuyo Gokuden, Shuetsu Fukushi, Masayuki Saijo, Fumiko Nakadouzono, Yuka Iwamoto, Mami Yamamoto, Nodoka Hozumi, Kouichiro Nakayama, Kanji Ishitani, Nobuyuki Nishi, Mitsuhiro Ootsubo
Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne infectious disease with a high rate of mortality. It is caused by the SFTS virus (SFTSV). SFTS is endemic to western Japan, including the Kagoshima prefecture. Here, healthy persons living in Kagoshima prefecture were examined to assess the anti-SFTSV seroprevalence. An initial study was performed using serum samples collected from a total of 646 persons living in Kagoshima. At the same time, a questionnaire was used to collect information (occupation and history of being bitten by tick)...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709982/performance-of-genotypic-tropism-determination-on-hiv-1-crf01_ae-isolates-in-japan
#11
Masakazu Matsuda, Séverine Louvel, Wataru Sugiura, Alexandra Haas, Nico Pfeifer, Yoshiyuki Yokomaku, Yasumasa Iwatani, Rolf Kaiser, Thomas Klimkait
No abstract text is available yet for this article.
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709981/plasmid-mediated-ampc-%C3%AE-lactamase-and-underestimation-of-extended-spectrum-%C3%AE-lactamase-in-cefepime-susceptible-elevated-ceftazidime-mic-enterobacteriaceae-isolates
#12
Fumitaka Nishimura, Yoshitomo Morinaga, Norihiko Akamatsu, Junichi Matsuda, Norihito Kaku, Kazuaki Takeda, Naoki Uno, Kosuke Kosai, Hiroo Hasegawa, Katsunori Yanagihara
Phenotypic detection of extended-spectrum β-lactamase (ESBL) is important for public health and infection control; however, plasmid-mediated AmpC β-lactamases (pAmpCs) can interfere with the ESBL-phenotyping. We focused on Enterobacteriaceae strains which were susceptible to cefepime but had mildly-elevated MIC of ceftazidime, and studied the impact of pAmpC on the ESBL-phenotyping in this population. Genotyping of ESBL and pAmpC were performed on 528 clinical isolates of Escherichia coli, Klebsiella spp...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709980/on-case-fatality-rate-h7n9-influenza-resurgence-in-china-in-2017
#13
Hiroshi Yoshikura
No abstract text is available yet for this article.
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709979/molecular-evidence-of-chandipura-virus-from-sandflies-sergentomyia-spp-in-gujarat-india
#14
Rekha Gangadhar Damle, Vasudha Sankararaman, Vandana Sunil Bhide, Vinayak Kashinath Jadhav, Atul Madhukar Walimbe, Mangesh Damodar Gokhale
The spread and establishment of Chandipura virus (CHPV) infection in India has raised serious epidemiological concerns. Virus interface with the vertebrate hosts, humans and vector competence are the important parameters of disease prevalence. Interestingly, in the present study a highly zoophilic species of sandfly Sergentomyia is emerging as a potential vector of CHPV in Gujarat. It is probably the first report from India that male sandflies have been found to be positive for CHPV by RT-PCR. These finding signifies the vertical transmission of the virus among sandflies and has epidemiological significance...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709978/epidemic-keratoconjunctivitis-cases-resulting-from-adenovirus-type-8-and-54-detected-at-fukuoka-university-hospital-between-2014-and-2015
#15
Tomoko Tsukahara-Kawamura, Tsuguto Fujimoto, Gabriel Gonzalez, Nozomu Hanaoka, Masami Konagaya, Takeshi Arashiro, Yusuke Saeki, Eiichi Uchio
No abstract text is available yet for this article.
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709977/report-of-relapse-typhoid-fever-cases-from-kolkata-india-recrudescence-or-reinfection
#16
Sriparna Samajpati, Surojit Das, Ujjwayini Ray, Shanta Dutta
Three relapse cases out of 107 hospital attending typhoid cases within a period of 2 years (2014-2016) from Apollo Geneagles hospital, Kolkata, India were reported. Of three cases, two were treated with ceftriaxone for 7 days and one was for 14 days in the first episode of typhoid fever. Six Salmonella Typhi (S. Typhi) isolates, obtained from three patients in both the episodes, were subjected to antimicrobial susceptibility test (AST), detection of QRDR mutation and molecular subtyping by PFGE, MLVA, MLST, CRISPR and H58 haplotyping...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709976/tuberculosis-disease-among-healthcare-workers-clinical-microbiological-characteristics-and-treatment-outcomes-at-chiang-mai-university-hospital-thailand
#17
Juthamas Inchai, Chalerm Liwsrisakun, Chaiwat Bumroongkit, Juntima Eauthrongchit, Pattraporn Tajareunmuang, Chaicharn Pothirat
Tuberculosis (TB) among healthcare workers (HCWs) highly impacts morbidity and TB transmission in hospital. A retrospective cohort study of TB among HCWs (HCW-TB) was conducted using a registered database from 2003 to 2016 at Chiang Mai University Hospital to determine clinical and microbiological characteristics and treatment outcomes of HCW-TB. Seventy-six cases of HCWs, 54 nurses (71.1%), 12 physicians (15.8%) and 10 paramedics (13.2%), were diagnosed with TB disease. Female to male ratio of 51:25, mean age of 37...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709975/isolation-of-egg-adapted-influenza-a-h3n2-virus-without-amino-acid-substitutions-in-the-antigenic-sites-of-its-hemagglutinin
#18
Tomoko Kuwahara, Emi Takashita, Seiichiro Fujisaki, Masayuki Shirakura, Kazuya Nakamura, Noriko Kishida, Hitoshi Takahashi, Noriko Suzuki, Yoshihiro Kawaoka, Shinji Watanabe, Takato Odagiri
Antigenic changes in the hemagglutinin protein of recent A(H3N2) viruses are often induced when these viruses adapt to their egg hosts. We have successfully isolated an egg-adapted influenza A(H3N2) virus, A/Saitama/103/2014, without amino acid substitutions in the antigenic sites of its hemagglutinin protein but multiple substitutions in its neuraminidase protein by serial egg passages of a cell-propagated virus. Antigenic analysis of this egg-adapted A/Saitama/103/2014 virus indicated that its antigenicity did not change from the WHO prototype cell-propagated vaccine virus, A/Hong Kong/4801/2014...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709974/respiratory-syncytial-virus-surveillance-system-in-japan-assessment-of-recent-trends-2008-2015
#19
Kazuhiko Kanou, Yuzo Arima, Hitomi Kinoshita, Hiroaki Ito, Hideo Okuno, Naruo Saito, Tomimasa Sunagawa, Hirokazu Kimura, Tamano Matsui, Kazunori Oishi
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract illness in infants and young children. In Japan, surveillance for RSV infection started in 2003 based on approximately 3,000 pediatric sentinel sites. In recent years, RSV notifications have increased, but interpretation of trends has been challenging due to suspected increase in testing and expansion of the insurance coverage for RSV testing to include certain outpatients in late 2011. Therefore, we evaluated RSV surveillance data during 2008-2015, considering the number of sites that reported at least one RSV case during a surveillance year and restricting to sites that had continuous reporting status since 2008...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29709973/short-term-efficacy-and-safety-of-adding-ezetimibe-to-currently-used-lipid-lowering-drugs-in-thai-hiv-infected-patients-receiving-protease-inhibitors
#20
Krisda Boonthos, Chankit Puttilerpong, Thitima Pengsuparp, Weerawat Manosuthi
Long-term complication of protease inhibitors (PIs) includes increased cardiovascular risks in HIV-infected patients due to dyslipidemia. Ezetimibe reduces LDL-C without drug interaction to PIs and statins. Furthermore, addition of ezetimibe on statins is an optional treatment in HIV-infected patients with uncontrolled dyslipidemia. The objective of this study was to determine short-term efficacy and safety of adding ezetimibe to currently used statins. Thirty-two patients received ezetimibe 10 mg daily added to their ongoing lipid-lowering therapy for 18 weeks...
April 27, 2018: Japanese Journal of Infectious Diseases
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