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Japanese Journal of Infectious Diseases

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https://www.readbyqxmd.com/read/30381693/development-and-evaluation-of-new-real-time-rt-pcr-assays-for-identifying-the-influenza-a-virus-cluster-iv-h3n2-variant
#1
Shinji Saito, Mina Nakauchi, Ikuyo Takayama, Shiho Nagata, Takato Odagiri, Tsutomu Kageyama
From 2005 to July 6, 2018, a total of 435 swine-origin influenza A H3N2 variant virus (H3N2v) human infections were reported in the USA. The largest H3N2v outbreak in the USA occurred in 2011-2012. This virus obtained the HA gene from human seasonal H3N2 influenza A viruses (seasonal H3N2) via human-to-swine transmission in the mid-1990s and was classified as Cluster IV H3N2v. For early detection of public health threats associated with Cluster IV H3N2v in distinction from seasonal H3N2, we developed highly specific and sensitive one-step real-time RT-PCR assays directly targeting the HA genes of Cluster IV H3N2v and seasonal H3N2...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381692/invasive-fungal-infection-caused-by-geotrichum-clavatum-in-an-acute-leukemia-child-first-documented-case-from-mainland-china
#2
Xingxin Liu, Wei Zhou, Yongmei Jiang, Linghan Kuang
Invasive fungal infections (IFIs) are one of the vital complications for acute leukemia patients undergoing induction chemotherapy. Among them, Geotrichum clavatum fungal infections present extremely rare with atypical clinical symptoms which make it difficult to diagnosis. In this paper, we report a case of infection caused by Geotrichum clavatum in a 10-year old acute leukemia child, which is the first documented case from mainland China. With childhood leukemia as the basic disease, the child suffered from repeated bacterial and fungal infection, and even underwent abdominal surgery during the treatment...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381691/comparison-of-established-pcr-assays-for-accurate-identification-of-campylobacter-jejuni-and-campylobacter-coli
#3
S M Lutful Kabir, Nityananda Chowdhury, Masahiro Asakura, Sachi Shiramaru, Ken Kikuchi, Atsushi Hinenoya, Sucharit Basu Neogi, Shinji Yamasaki
Proper surveillance of Campylobacter jejuni and Campylobacter coli, major pathogens associated with human gastroenteritis, is necessary to tackle the increasing disease burden. To detect these pathogenic species, a variety of PCR assays have been developed. This study examined the sensitivity and specificity of 12 PCR assays targeting 23S rRNA, ceuE, lpxA, hipO, mapA, ask, and cdt genes of C. jejuni and C. coli. The PCR assays had sensitivity of 85.2-100%, and 97-100%, and specificity of 90.5-100%, and 94.3-100% for the tested C...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381690/persistence-of-antibodies-against-diphtheria-tetanus-pertussis-and-poliovirus-types-i-ii-and-iii-following-immunization-with-dtap-combined-with-inactivated-wild-type-polio-vaccine-dtap-wipv
#4
Tetsuo Nakayama, Shigeru Suga, Kenji Okada, Nobuhiko Okabe
A follow-up serological study was conducted involving 47 subjects who received four doses of diphtheria and tetanus toxoids combined with acellular pertussis vaccine (DTaP) together with Salk-type inactivated polio vaccine (DTaP-wIPV) until 6 years of age. All antibody levels declined more rapidly than expected within 3 years after the completion of the primary vaccination with 4th booster dose and titers persisted until 6 years of age. The positive rate of the IgG antibody against pertussis toxin (PT) was 31...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381689/indication-of-minimum-inhibitory-concentration-of-%C3%AE-lactam-antimicrobials-for-the-primary-extraction-of-imp-producing-enterobacteriaceae
#5
Kyoichi Saito, Kiwamu Nakamura, Rie Harada, Ryuichi Nakano, Hisakazu Yano, Keiji Kanemitsu
No abstract text is available yet for this article.
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381688/does-quick-sepsis-related-organ-failure-assessment-qsofa-suggest-the-use-of-initial-empirical-carbapenem-therapy-in-bacteremia-caused-by-extended-spectrum-%C3%AE-lactamase-producing-bacteria-a-multicenter-case-control-study
#6
Satoru Mitsuboshi, Naoki Tsuruma, Kazuya Watanabe, Shigehiro Takahashi, Manami Nakashita, Atsuko Ito, Kenichi Kobayashi, Masami Tsugita
We hypothesized that quick Sequential Organ Failure Assessment (qSOFA) would be associated with 30-day mortality in bacteremia caused by extended-spectrum β-lactamase (ESBL)-producing bacteria and might be a selection criterion for the use of carbapenem as initial empirical therapy. A multicenter retrospective study was conducted in six hospitals. All patients who had bacteremia due to ESBL-producing bacteria were included in the study. Multivariable logistic regression analysis was performed to analyze 30-day mortality as the main outcome...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381687/a-novel-recombinant-norovirus-gii-4-sydney-2012-strain-detected-from-a-food-poisoning-outbreak-in-the-2017-2018-season-japan
#7
Noriko Inasaki, Yumiko Aoyagi, Seiji Morioka, Sumiyo Hasegawa, Tetsuya Yoneda, Yumiko Saga, Masae Itamochi, Masatsugu Obuchi
No abstract text is available yet for this article.
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381686/infectious-keratitis-microbiological-review-of-297-cases
#8
Daniel Tena, Natividad Rodríguez, Laura Toribio, Alejandro González-Praetorius
Infectious keratitis is a serious ocular infection that can lead to loss of vision. The aim of the study was to investigate the microbiological characteristics of this infection at the University Hospital of Guadalajara (Spain). We retrospectively reviewed all cases diagnosed between January 2010 and December 2016. During the 7-year study period, 297 corneal scrapes corresponding to 298 patients were performed. Antibiotic treatment previous to the culture occurred in 59 cases (19.5%). Contact lens wear was the most common risk factor (33...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381685/an-outbreak-of-rhinovirus-species-c-infection-in-a-welfare-facility-in-fukuoka-prefecture-japan
#9
Yuki Ashizuka, Asako Nakamura, Hideaki Yoshitomi, Takayuki Kobayashi, Jumboku Kajiwara, Susumu Katsuki, Makoto Kuroda
No abstract text is available yet for this article.
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381684/the-cost-effective-easy-competitive-elisa-cee-celisa-available-for-monitoring-protective-immunity-against-the-rabies-virus-in-sera-of-humans-and-dogs
#10
Yada Aronthippaitoon, Waraporn Samer, Thitima Atuntee, Hathairat Thananchai, Kriangkrai Thongkorn, Pornsawan Pongsopawijit, Satoshi Inoue, Akira Noguchi, Eun-Sil Park, Akihito Kawai, Wilaiwan Petsophonsakul
The rabies vaccinations coverage has been reported as 70-80% of dogs in annual reports. However, there are still outbreaks of rabies in humans and dogs in Thailand, which indicate the necessity of ensuring seroprevalence in vaccinated dogs and efficacy of human immunization. The cost effective easy competitive ELISA (CEE-cELISA) was developed for monitoring protective immunity against the rabies virus in human and dog sera by using the monoclonal antibody clone 1-46-12, which recognized a conformation epitope of rabies G protein, with an ELISA plate coated with whole viral antigen of commercial vaccine...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381683/effects-of-a-public-subsidization-program-for-mumps-vaccine-on-reducing-the-disease-burden-in-nagoya-city-japan
#11
Takao Ozaki, Yasuhiro Goto, Naoko Nishimura, Takashi Nakano, Hideaki Kumihashi, Munehide Kano, Satoko Ohfuji
Nagoya City initiated a public subsidization program for mumps vaccination using either Torii- or Hoshino-strains in August 2010. To demonstrate the effects of the program, we used publicly available information from Nagoya City to investigate the changes in immunization rate and numbers of patients who developed post-immunization adverse reactions, including post-vaccinal aseptic meningitis, in the 7 years since its initiation. We also investigated the numbers of mumps patients reported during this period by sentinel sites in a national database...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381682/neutralization-potency-of-sera-from-vietnamese-patients-with-japanese-encephalitis-je-against-genotypes-i-and-v-je-viruses
#12
Thi Thu Thuy Nguyen, Shigeru Tajima, Makiko Ikeda, Thu Trang Nguyen, Thi Hien Thu Le, Thi Thu Hang Pham, Do Quyen Pham, Thi Quynh Mai Le, Takahiro Maeki, Satoshi Taniguchi, Fumihiro Kato, Meng Ling Moi, Koichi Morita, Chang-Kweng Lim, Masayuki Saijo, Futoshi Hasebe
Japanese encephalitis virus (JEV) is classified into five genotypes (GI, GII, GIII, GIV, and GV), and the GI and GIII strains have been the most widely distributed in JE endemic areas. In recent years, GV JEV has been detected in China and Korea, suggesting that GV JEV may invade other JE endemic areas, including Vietnam, and that more attention should be paid to JEV strains circulating in these areas. In this study, we investigated the neutralization ability of the sera collected from 22 Vietnamese JE patients who lived in northern Vietnam against GI and GV JEV strains...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381681/species-identification-of-%C3%AE-hemolytic-streptococci-from-diseased-companion-animals-and-their-antimicrobial-resistance-data-in-japan-2017
#13
Yasuto Fukushima, Yuzo Tsuyuki, Mieko Goto, Haruno Yoshida, Takashi Takahashi
This study determined species identification and antimicrobial resistance (AMR) properties in β-hemolytic streptococci isolated from companion animals in Japan. Strains were isolated from clinical specimens of 131 companion animals with symptoms/signs in April-May, 2017. We identified strains by 16S rRNA sequencing and antimicrobial susceptibility was determined using the broth microdilution method. AMR genes (erm(A)-erm(B)-mef(A) and tet(M)-tet(O)-tet(K)-tet(L)-tet(S)) in all isolates were amplified by PCR...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381680/assessment-of-bacteremia-in-a-large-tertiary-care-hospital-in-northern-vietnam-a-single-center-retrospective-surveillance-study
#14
Nozomi Takeshita, Nguyen Quoc Anh, Doan Mai Phuong, Do Van Thanh, Pham Phuong Thuy, Mai Thi Lan Huong, Manami Takahashi, Norio Ohmagari
The clinical analysis of cases of Bacteremia would be valuable. However, thus far, limited data on bacteremia are available in Vietnam. A single-center, retrospective surveillance study was conducted in Bach Mai Hospital, Hanoi, Vietnam from 2009 to 2012. In total, 45,366 blood culture cases were analyzed. The number of blood cultures per 1,000 patient-days was 9.59 sets. The percentage of solitary blood culture sets was 49.6%. The rate of positive blood culture was 13.9%. The major pathogens isolated in adults were coagulase-negative Staphylococcus species (16...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381679/possible-reintroduction-of-taenia-asiatica-into-the-kanto-region-of-japan
#15
Daisuke Taniyama, Izumi Inoue, Megumi Kawano, Chiaki Arakawa, Tomohide Adachi, Yasuyuki Morishima, Hiroshi Yamasaki, Hiromu Sugiyama
No abstract text is available yet for this article.
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381678/detection-of-uncommon-enteric-bacterial-pathogens-from-acute-diarrheal-specimens-using-sybr-green-real-time-pcr
#16
Goutam Chowdhury, Oscar C Stine, Krishnan Rajendran, Asish K Mukhopadhyay, Keinosuke Okamoto, Thandavarayan Ramamurthy
Acute diarrheal disease is a major health problem and second most common cause of death in children under five years of age. Conventional diagnostic methods are laborious, time consuming and occasionally inaccurate. We examined SYBR-Green real-time PCR for the detection of ten uncommon bacterial pathogens using fecal specimens from acute diarrheal patients. In SYBR-Green real-time PCR, the products formed were identified based on melting point temperature (Tm ) curve analysis and was validated with the respective reference strain...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381677/loop-mediated-isothermal-amplification-for-rapid-identification-of-mycobacterium-tuberculosis-in-comparison-with-immunochromatographic-sd-bioline-mpt64-rapid-%C3%A2-in-a-high-burden-setting
#17
Benjawan Phetsuksiri, Janisara Rudeeaneksin, Sopa Srisungngam, Supranee Bunchoo, Wiphat Klayut, Somchai Sangkitporn, Chie Nakajima, Shigeyugi Hamada, Yasuhiko Suzuki
Loop-mediated isothermal amplification (LAMP) was assessed for rapid identification of Mycobacterium tuberculosis complex (MTC) in comparison with an immunochromatographic test (ICT) using SD Bioline Ag MPT64 Rapid® . One hundred and fifty-one MGIT cultures positive for acid-fast bacilli (AFB) were tested for MTC. DNA was extracted from a small portion of culture samples by heat lysis and subjected to LAMP analysis. Of these, 1445 were positive and 5 were negative by both tests. One culture that was ICT negative but that was LAMP positive was confirmed to have a mutation in the mpt64 gene...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30381676/predomination-shift-of-different-p44-expressing-anaplasma-phagocytophilum-in-infected-hl-60-thp-1-nb4-and-rf-6a-cell-lines
#18
Masahiko Shimada, Naoya Takamoto, Hongru Su, Haruka Sasahara, Yuko Shimamura, Shuji Ando, Norio Ohashi
Anaplasma phagocytophilum, an agent of human granulocytic anaplasmosis, is an obligatory intracellular bacterium and dominantly produces the variety of P44 major outer membrane proteins encoded by a p44/msp2 multigene family, that is responsible as major antigens for serodiagnosis. However, A. phagocytophilum antigens prepared from cultures with different cell lines seems to have various reactivities with patients' sera. In this study, we performed RNA-seq to investigate P44 expression of A. phagocytophilum propagated in 4 different cell lines...
October 31, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30270252/a-case-of-hepatitis-a-infection-presumed-to-be-related-to-asari-clams-and-investigation-on-spread-of-viral-contamination-from-asari-clams
#19
Ryusuke Tsukada, Satoko Ono, Hiroki Kobayashi, Yumi Wada, Kanako Nishizawa, Masumi Fujii, Michiko Takeuchi, Kazuo Kuroiwa, Yoshikiyo Kobayashi, Koji Ishii, Haruyuki Nakazawa
In a case of hepatitis A infection that occurred in 2017 in Nagano Prefecture, hepatitis A virus (HAV) was detected in asari clams (reference food) and the patients' fecal samples. Initially, the asari clams were suspected to be the infection source. However, as a patient who had not consumed a asari clam dish also developed the disease, the exact infection route remained unknown. Suspecting a secondary infection originating from the asari clams, we investigated the presence of HAV genomes in water used for washing and soaking the frozen asari clams and detected HAV in the "Soaking Water...
September 28, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/30270251/age-distribution-of-people-dying-of-hiv-aids-that-shifted-towards-older-ages-by-ten-years-in-the-past-twenty-odd-years
#20
Hiroshi Yoshikura
The frequency of the ages of the HIV/AIDS deaths and that of the patients detected before or after the development of AIDS followed normal distribution. The median of HIV/AIDS deaths was 40-44 years in 1995-1998 and 50-54 years in 2014-2016, while the median of detection of the infection as "HIV" or as "AIDS" was constantly 25-29 years; it implied that the survival time of the HIV/AIDS patients became longer by 10 years in the past twenty odd years. The lengthening of the survival time could have been attributable to introduction of HIV/AIDS therapy, such as HAART...
September 28, 2018: Japanese Journal of Infectious Diseases
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